成花素激活复合物
技术领域
[0001]本发明涉及成花素通过14-3-3蛋白与bZIP转录因子结合而形成的成花素激活复合物的晶体、和由该晶体得到的成花素激活复合物的立体结构信息以及成花素激活复合物的功能的利用。
[0002]本申请要求通过参考而援引于此的日本申请特愿2010-061562号的优先权。
背景技术
[0003]对于稳定的粮食生产或者有效利用了植物生物量等的循环型经济社会系统的构建的实现来说，认为各种环境下的植物的开花的调节是有效的。为了构建调节植物开花的技术，需要弄清楚植物环境响应的信息传达的分子基础。
[0004]作为诱导植物开花的因素，成花素的存在在70年前就被提倡，近年来，已经明确了其实体为高等植物中普遍存在的FT基因的产物。成花素是在达到最适于花芽形成的日长时在叶子中合成，并向茎顶端移动从而使成花开始的分子。在水稻中，Hd3a被认为相当于成花素而促进抽穗，从而提出了将水稻Hd3a基因用于植物的开花调节中（专利文献I、非专利文献I)。
[0005]有报告称水稻Hd3a与水稻14_3_3蛋白GF14c相互作用，由此抑制性地控制成花(非专利文献2)。在非专利文献2中，使用酵母双杂交法对与Hd3a相互作用的蛋白质进行了筛选，发现水稻的14-3-3蛋白GF14c与Hd3a相互作用。GF14c主要定位于细胞质中，这暗示Hd3a与GF14c的复合物主要存在于细胞质中。由当过量表达GF14c时成花延迟的情况等可以认为，GF14c是抑制成花的因素。
[0006]在鼠耳芥中，认为作为成花素的实体的FT蛋白质在细胞核内与bZIP转录因子FD等相互作用，从而有助于花分生组织确定基因（flower meristem identity gene)的表达(非专利文献3、4)。有报告将bZIP转录因子使用于成花控制中（专利文献2)。
[0007]虽然关于成花素的研究报告有很多，但是，开花诱导中的成花素的作用机制仍不明确。
[0008]【在先技术文献】
[0009]【专利文献】
[0010]专利文献I :日本公开公报、特开2002-153283号
[0011]专利文献2 :日本公开公报、特开2003-274972号
[0012]【非专利文献】
[0013]非专利文献I :Tamaki S et al. Science (2007) vol. 316 (5827) pp. 1033-6
[0014]非专利文献2 :Purwestri YA et al. Plant and Cell Physiology 2009 50(3)：429-438
[0015]非专利文献3 ：ffigge et al. Science (2005) vol. 309 (5737) pp. 1056-9
[0016]非专利文献4 ：Abe et al. Science (2005) vol. 309 (5737) pp. 1052-6发明内容
[0017]本发明的课题在于，提供成花素通过14-3-3蛋白与bZIP转录因子结合而形成的成花素激活复合物的晶体，并且，利用该晶体而将上述蛋白质间的相互作用机制明确，并对该相互作用进行控制，由此来调节植物的成花。
[0018]为了解决上述课题，本发明者们进行了潜心研究，结果在成花素通过14-3-3蛋白与bZIP转录因子结合而形成的成花素激活复合物的晶化上获得成功，并且发现利用由该成花素激活复合物的晶体得到的立体结构信息来控制相互作用机制，能够调节植物的成花，从而完成了本发明。
[0019]即，本发明由以下内容构成。
[0020]I. 一种植物的成花的调节方法，其包括：在由成花素、14-3-3蛋白以及bZIP转录因子的复合物构成的成花素激活复合物中，对成花素与14-3-3蛋白的结合部位和/或14-3-3蛋白与bZIP转录因子的结合部位施加影响，由此来促进和/或抑制成花素激活复合 物的形成，
[0021]成花素与14-3-3蛋白的结合部位是选自由相当于序列编号I中的D62、M63、R64、P96、T98、F103及R132的成花素的部位和相当于序列编号2中的F200、D201、1204、E212、Y215、R226及D227的14_3_3蛋白的部位构成的群中的I个以上的部位，
[0022]14-3-3蛋白与bZIP转录因子的结合部位是选自由相当于序列编号2中的K51、R58、F121、R131、L224及D227的14-3-3蛋白的部位和相当于序列编号3中的R189〜F195的bZIP转录因子的部位构成的群中的I个以上的部位。
[0023]2.上述I中所述的植物的成花的调节方法，其中，
[0024]促进和/或抑制成花素激活复合物的形成是指制备含有以下的（A)〜（C)中的任一种以上的蛋白质的转化体，
[0025](A)成花素与14-3-3蛋白的I个以上的结合部位发生了变异的成花素，
[0026](B)成花素与14-3-3蛋白的I个以上的结合部位和/或14_3_3蛋白与bZIP转录因子的I个以上的结合部位发生了变异的14-3-3蛋白，
[0027](C) 14-3-3蛋白与bZIP转录因子的I个以上的结合部位发生了变异的bZIP转录因子。
[0028]3. 一种转化体，其是含有以下的（A)〜（C)中的任一种以上的蛋白质的转化体：
[0029](A)成花素与14-3-3蛋白的I个以上的结合部位发生了变异的成花素，
[0030](B)成花素与14-3-3蛋白的I个以上的结合部位和/或14_3_3蛋白与bZIP转录因子的I个以上的结合部位发生了变异的14-3-3蛋白，
[0031](C) 14-3-3蛋白与bZIP转录因子的I个以上的结合部位发生了变异的bZIP转录因子；
[0032]其中，成花素与14-3-3蛋白的结合部位是选自由相当于序列编号I中的D62、M63、R64、P96、T98、F103及R132的成花素的部位和相当于序列编号2中的F200、D201、I204、E212、Y215、R226及D227的14_3_3蛋白的部位构成的群中的I个以上的部位，
[0033]14-3-3蛋白与bZIP转录因子的结合部位是选自由相当于序列编号2中的K51、R58、F121、R131、L224及D227的14-3-3蛋白的部位和相当于序列编号3中的R189〜F195的bZIP转录因子的部位构成的群中的I个以上的部位。[0034]4. 一种多核苷酸，其编码以下的⑷〜（C)中的任一种以上的蛋白质：
[0035](A)成花素与14-3-3蛋白的I个以上的结合部位发生了变异的成花素，
[0036](B)成花素与14-3-3蛋白的I个以上的结合部位和/或14_3_3蛋白与bZIP转录因子的I个以上的结合部位发生了变异的14-3-3蛋白，
[0037](C) 14-3-3蛋白与bZIP转录因子的I个以上的结合部位发生了变异的bZIP转录因子；
[0038]在此，成花素与14-3-3蛋白的结合部位是选自由相当于序列编号I中的D62、M63、R64、P96、T98、F103及R132的成花素的部位和相当于序列编号2中的F200、D201、1204、E212、Y215、R226及D227的14_3_3蛋白的部位构成的群中的I个以上的部位，
[0039]14-3-3蛋白与bZIP转录因子的结合部位是选自由相当于序列编号2中的K51、 R58、F121、R131、L224及D227的14_3_3蛋白的部位和相当于序列编号3中的R189〜F195的bZIP转录因子的部位构成的群中的I个以上的部位。
[0040]5. 一种重组载体，其含有上述4中所述的任一种以上的多核苷酸。
[0041]6. 一种控制植物的成花的物质的筛选方法，其包括以下的任一工序：
[0042](I)使候选物质与成花素或14-3-3蛋白中的任一种接触，然后使候选物质与14-3-3蛋白或成花素接触的工序；或者
[0043](2)使候选物质与结合有或未结合有成花素的14-3-3蛋白或者bZIP转录因子中的任一种接触，然后使候选物质与bZIP转录因子或者结合有或未结合有成花素的14-3-3蛋白接触的工序。
[0044]7.上述6中所述的调节植物的成花的物质的筛选方法，其还包括以下的工序：
[0045]选择成花素与14-3-3蛋白的结合部位和/或14-3-3蛋白与bZIP转录因子的结合部位上的结合在候选物质的存在下被促进和/或阻碍的物质的工序，
[0046]其中，成花素与14-3-3蛋白的结合部位是选自由相当于序列编号I中的D62、M63、R64、P96、T98、F103及R132的成花素的部位和相当于序列编号2中的F200、D201、1204、E212、Y215、R226及D227的14_3_3蛋白的部位构成的群中的I个以上的部位，
[0047]14-3-3蛋白与bZIP转录因子的结合部位是选自由相当于序列编号2中的K51、R58、F121、R131、L224及D227的14-3-3蛋白的部位和相当于序列编号3中的R189〜F195的bZIP转录因子的部位构成的群中的I个以上的部位。
[0048]8.上述6或7中所述的调节植物的成花的物质的筛选方法，其中，
[0049]成花素是至少含有序列编号I中所示的氨基酸序列中的第62〜132位的氨基酸序列，并且含有以第I〜6位中的I个氨基酸开始且以第165〜177位中的I个氨基酸结束的氨基酸序列的成花素多肽片段，
[0050]14-3-3蛋白是至少含有序列编号2中所示的氨基酸序列中的第51〜227位的氨基酸序列，并且含有以第I〜5位中的I个氨基酸开始且以第230〜256位中的I个氨基酸结束的氨基酸序列的14-3-3蛋白的多肽片段，
[0051]bZIP转录因子是至少含有序列编号3中所示的氨基酸序列中的第189〜195位的氨基酸序列，并且含有以第182〜188位中的I个氨基酸开始且以第195位氨基酸结束的氨基酸序列的bZIP转录因子多肽片段。
[0052]9. 一种多肽片段，其是选自以下的多肽片段：[0053](i)至少含有序列编号I中所示的氨基酸序列中的第62〜132位的氨基酸序列，并且含有以第I〜6位中的I个氨基酸开始且以第165〜177位中的I个氨基酸结束的氨基酸序列的新型成花素多肽片段；
[0054](ii)至少含有序列编号2中所示的氨基酸序列中的第51〜227位的氨基酸序列，并且含有以第I〜5位中的I个氨基酸开始且以第230〜256位中的I个氨基酸结束的氨基酸序列的新型14-3-3蛋白多肽片段；
[0055](iii)至少含有序列编号3中所示的OsFDl的第189〜195位的氨基酸序列，并且以第182〜188位中的I个氨基酸开始且以第195位的氨基酸结束的新型bZIP转录因子多肽片段。
[0056]10. 一种多核苷酸，其编码上述9的（i)〜（iii)中所述的多肽片段。
[0057]11. 一种成花素激活复合物，其是成花素多肽片段通过14-3-3蛋白多肽片段与bZIP转录因子多肽片段结合而形成的成花素激活复合物，
[0058]其中，成花素多肽片段、14-3-3蛋白多肽片段以及bZIP转录因子多肽片段分别为上述9的⑴〜（iii)中所述的多肽片段。
[0059]12. 一种成花素激活复合物的晶体，其是成花素通过14-3-3蛋白与bZIP转录因子结合而形成的。
[0060]13.上述12中所述的成花素激活复合物的晶体，其中，晶体的空间群为P1、P6522或者P4,晶格常数为 a=74 A 〜158 A、b=64 A〜158 A、c=96 A~500 A、α =66° 〜90°、β = 85° 〜90°、γ = 75° 〜120°。
[0061]14. 一种上述12或13中所述的成花素激活复合物的晶体的制备方法，其包括：
[0062]使用作为沉淀剂而至少含有容量百分比为5〜35的聚乙二醇的沉淀剂溶液,并通过蒸汽扩散法而将含有成花素与14-3-3蛋白的复合物的溶液晶化的工序；
[0063]回收得到的晶体的工序；以及
[0064]使用沉淀剂溶液对得到的晶体进行培养，从而得到成花素激活复合物的晶体的工序，其中，上述沉淀剂溶液作为沉淀剂而至少含有容量百分比为5〜35的聚乙二醇且含有bZIP转录因子。
[0065]15. 一种调节植物的成花的物质的筛选方法，其是使用计算机而设计和/或选择具有调节成花素激活复合物的活性的功能的候选物质，由此来筛选调节植物的成花的物质的方法，
[0066]其中，上述筛选方法包括：
[0067](a)将从上述12或13中所述的成花素激活复合物的晶体中得到的立体结构信息存储在存储手段中的工序，
[0068](b)根据立体结构信息并利用导出手段而导出三维立体结构模型的工序，
[0069](C)在导出的三维立体结构模型中，利用计算手段计算出原子间距离的工序，
[0070](d)根据计算出的原子间距离并利用计算手段而计算出候选物质的立体结构信息，从而设计和/或选择候选物质的工序，其中，上述候选物质能够增强和/或阻碍成花素与14-3-3蛋白的结合和/或14-3-3蛋白与bZIP转录因子的结合。
[0071]16. 一种转化体，其是成花素与14-3-3蛋白的结合和/或14-3-3蛋白与bZIP转录因子的结合被促进和/或抑制的转化体，其中，上述转化体中以能够表达的方式导入了上述10中所述的I种以上的多核苷酸。
[0072]17.上述12或13中所述的成花素激活复合物的晶体，其中，
[0073]成花素是至少含有序列编号I中所示的氨基酸序列中的第62〜132位的氨基酸序列，并且含有以第I〜6位中的I个氨基酸开始且以第165〜177位中的I个氨基酸结束的氨基酸序列的多肽片段，
[0074]14-3-3蛋白是至少含有序列编号2中所示的氨基酸序列中的第51〜227位的氨基酸序列，并且含有以第I〜5位中的I个氨基酸开始且以第230〜256位中的I个氨基酸结束的氨基酸序列的多肽片段，
[0075]bZIP转录因子是至少含有序列编号3中所示的氨基酸序列中的第189〜195位的氨基酸序列，并且含有以第182〜188位中的I个氨基酸开始且以第195位的氨基酸结束的氨基酸序列的多肽片段。 [0076]18.上述12、13以及17任一项所述的成花素激活复合物的晶体，其中，
[0077]成花素是含有序列编号I中所示的氨基酸序列中的第6〜170位的氨基酸序列的多肽，14-3-3蛋白是含有序列编号2中所示的氨基酸序列中的第I〜235位的氨基酸序列的多肽，bZIP转录因子是含有序列编号3中所示的氨基酸序列中的第187〜195位的氨基酸序列的多肽。
[0078]19.上述12、13、17以及18任一项所述的成花素激活复合物的晶体，其是选自以下的成花素激活复合物的晶体：
[0079](I)晶体的空间群为Pl，晶格常数为a=74 A~79 A、b=94 A〜99 A、c=96A~10lA、a = 66。〜70。、β = 85。〜90。、γ = 75。〜79。的晶体；
[0080](2)晶体的空间群为P6522，晶格常数为a=125 A〜135 A、b=125 A〜135 A、c=340A〜344A、α = 90°、β = 90°、Y =120。的晶体；
[0081]⑶晶体的空间群为Ρ4，晶格常数为a=153 Α-158 A、b=153 A〜158Α、c=495 A~498 A、α = 90°、β = 90°、γ = 90° 的晶体。
[0082]20.上述12、13、17〜19任一项所述的成花素激活复合物的晶体，其是选自以下的成花素激活复合物的晶体：
[0083](I)晶体的空间群为 P1，晶格常数为 a=76.7 A、b=96.6 A、c=99.5 A、α =68. 2°、β = 87. 9°、γ = 77. 9° 的晶体；
[0084](2)晶体的空间群为 Ρ1，晶格常数为 a=76.8 A、b=97.3 A、c=99.8 A、α =68. 1°、β = 87. 8°、γ = 77. 9° 的晶体；
[0085](3)晶体的空间群为 Ρ1，晶格常数为 a=76.2 A、b=96.1 A、c=99..1 A、α =68. 2°、β = 88. 6°、γ = 77. 8° 的晶体；
[0086](4)晶体的空间群为 Ρ6522,晶格常数为 a=129.0 A、b=129.0 A、c=342.0 A、α=90°、β = 90°、γ = 120。的晶体；
[0087](5)晶体的空间群为 Ρ4,晶格常数为 a=l55.9 A、b=l55.9 A、c=496.4 A、α =90。、β = 90。、γ = 90。的晶体。
[0088]21.上述14中所述的成花素激活复合物的晶体的制备方法，其中，含有成花素与14-3-3蛋白的复合物的溶液的浓度为5mg/mL〜40mg/mL，将成花素与14_3_3蛋白的复合物晶化的工序中的沉淀剂溶液含有O. 05M〜O. IM HEPES (pH为6. 5〜8. 5)、0. OlM〜O. 4M硫酸铵、以及分子量为2000〜4000且容量百分比为15〜30的聚乙二醇，得到成花素激活复合物的晶体的工序中的沉淀剂溶液含有容量百分比为15〜30的乙二醇、ImM〜5mMbZIP转录因子、O. 05M〜O. IM HEPES (pH为6. 5〜8. 5)、O. 2M〜IM硫酸铵、以及分子量为2000〜4000且容量百分比为15〜30的聚乙二醇。
[0089]22.上述15中所述的调节植物的成花的物质的筛选方法，其中，上述立体结构信息为表I或表2中记载的信息。
[0090]23.上述15或22中所述的调节植物的成花的物质的筛选方法，其中，
[0091]成花素与14-3-3蛋白的结合部位是选自由序列编号I中的D62、M63、R64、P96、T98、F103 及 R132 和序列编号 2 中的 F200、D201、I204、E212、Y215、R226 及 D227 构成的群中的I个以上的部位，
[0092]14-3-3蛋白与bZIP转录因子的结合部位是选自由序列编号2中的K51、R58、F121、R131、L224及D227和序列编号3中的R189〜F195构成的群中的I个以上的部位。
[0093]24.上述15、22、23任一项所述的调节植物的成花的物质的筛选方法，其中，还包括获得上述被设计或选择的候选物质的工序、和为了研究上述候选物质的成花素激活复合物活性调节功能而使上述候选物质与成花素、14-3-3蛋白和/或bZIP转录因子接触的工序。
[0094]25.上述15、22〜24任一项所述的调节植物的成花的物质的筛选方法，其中，还包括：利用上述14或21中所述的成花素激活复合物的晶体的制备方法来制备成花素激活复合物的晶体的工序、和通过对该结晶进行X射线晶体结构分析而得到成花素激活复合物的立体结构信息的工序。
[0095](发明効果）
[0096]本发明的晶体能够带来对于弄清楚植物的成花调节机制很重要的成花素激活复合物的立体结构信息，并且，该晶体能够作为用于对成花调节机制进一步研究的材料而使用。另外，根据从本发明的晶体得到的立体结构信息，能够人为地调节植物的成花。在本发明中，明确了成花素激活复合物中的各蛋白质的结合部位，并且，能够将结合部位的信息作为成花调节的新型标的而使用，从而能够有效地进行成花调节。根据本发明中得到的立体结构信息，能够得到可广泛利用于农业生产物的收量增加或育种的効率化等的转基因植物。附图说明
[0097]图I是表示Hd3a、GF14c以及OsFDl这三者的成花素激活复合物的立体结构的图。
[0098]图2是表示关于Hd3a与OsFDl、Hd3a与GF14c、GF14c与OsFDl这三个组合的体外GST pull-down实验的结果的图。（实施例1(1))
[0099]图3是表示使用了 NMR的、Hd3a与GF14c的相互作用分析的结果的图。（实施例1(2))
[0100]图4是表示Hd3a与GF14c的相互作用的详细情况的图。图4b表示Hd3a R64周边的放大图。（实施例3)
[0101]图5是表示使用了变异型Hd3a的、与GF14c的体外GST pull-down实验的结果(图5a)和使用了变异型GF14c的、与Hd3a的体外GST pull-down实验的结果（图5b)的图。(实施例6)
[0102]图6是表示Hd3a、GF14c以及OsFDl的成花素激活复合物与C_box DNA的凝胶迁移实验的结果的图。（实施例7)
[0103]图7是表示使用酵母双杂交法确认0sGF14的各同种型与Hd3a的相互作用的结果的图。（实施例8)
[0104]图8是表示使用酵母双杂交法确认Hd3a、OsGF14b以及OsFDl各组的相互作用的结果的图。（实施例9)
[0105]图9是表示使用免疫沉淀法确认Hd3a、OsGF14b以及OsFDl的各组在水稻茎顶端的相互作用的结果的图。（实施例10)
[0106]图10是表示Hd3a、0sGF14b以及OsFDl的细胞内定位的确认结果的图。（实施例11)
[0107]图11是表示Hd3a、0sGF14b以及OsFDl的细胞内定位的确认结果的图。（实施例11)
[0108]图12是表示Hd3a、0sGF14b以及OsFDl的细胞内定位的确认结果的图。（实施例11)
[0109]图13是表示Hd3a、OsGF14b以及OsFDl的瞬时表达对0sMADS15基因的转录的影响的确认结果的图。（实施例12)
[0110]图14是表示Hd3a变异对植物的成花的影响的确认结果的图。（实施例13_1)
[0111]图15是表示通过本发明得到的成花素激活复合物的作用机制的图。
[0112]图16是表示Hd3a变异对植物的成花的影响的确认结果的图。（实施例13_2)
具体实施方式
[0113]植物一般具有营养生长期和生殖生长期，并且在生长相从营养生长向生殖生长转换时形成花芽。将该从营养生长向生殖生长的转换现象称为“成花”。例如单子叶植物的水稻或麦类中的成花为抽穗，所谓的抽穗是指穗下方的节距（穗颈）急速伸长从而从旗叶的叶鞘露出的现象。在水稻中将芒露出时称为抽穗，而在麦类中穗出到根部为止时称为抽穗。
[0114]在本发明中，植物是指具有成花素的高等植物，优选为在I天的日照时间为一定时间以下的情况下形成花芽的短日照植物，更优选为单子叶短日照植物，进而更优选为禾本科植物，最优选为水稻。
[0115](成花素激活复合物）
[0116]本发明是由成花素、14-3-3蛋白以及bZIP转录因子的复合物构成的成花素激活复合物，并且涉及由成花素通过14-3-3蛋白与bZIP转录因子结合而形成的成花素激活复合物。
[0117]在本发明中，成花素没有特别限定，可以例举出水稻的Hd3a、RFTI (GenbankAccession No. AB062676)、拟南芥的 FT (Genbank Accession No. AB027504)、TSF (GenbankAccession No. AB027506)、西红柿的 SFT (Genbank Accession No. AY186735)、小麦的VRN3 (Genbank Accession No. L0C100037541)等，优选为水稻 Hd3a。水稻 Hd3a 中含有序列编号 I 所不的氛基酸序列(0s06g0157700) (Genbank Accession No. BAB61028 :源自 Oryzasativa Japonica group cultivar Nipponbare)所表示的蛋白质、或者由在序列编号I的氨基酸序列中缺失、取代、附加和/或插入了 I个〜数个氨基酸残基后的氨基酸序列构成且作为成花素发挥功能的蛋白质。本发明中的水稻Hd3a优选为至少含有序列编号I中的第62〜132位氨基酸序列，并且以第I〜6位中的I个氨基酸开始且以第165〜177位中的I个氨基酸结束的成花素多肽片段，更优选为由序列编号I中的第6〜170位氨基酸序列构成的多肽片段。另外，特别优选该多肽片段具有序列编号I中的C43L/C109S/C166S的变巳
[0118]在本发明中，14-3-3蛋白没有特别限定，优选为水稻GF14。水稻GF14中具有 0sGF14a (0s08g0480800)、0sGF14b (0s04g0462500)、0sGF14c (0s08g0430500)、0sGF14d(0sllg0546900)、 0sGF14e(0s02g0580300)、 0sGF14f(0s03g0710800)、0sGF14g(0s01g0209200)、0sGF14h (0sllg0609600)这八个同种型（isoform)，在本发明中，优选为6?1仙、6?14(：、6?146、6?14乜更优选6?14(3或6?1413。需要说明的是，在本说明书中，以Os开始的编号只要没有特别说明，便是水稻注释计划数据库（Rice annotation project database,RAP-DB)中被特定的基因座的编号。可以根据这些编号来特定各GF14等的蛋白质的氨基酸序列和碱基序列。
[0119]水稻GF14c中含有序列编号2所示的氨基酸序列（0s08g0430500) (Genbank Accession No. AAB07457. I :源自 Oryza sativa Japonica group cultivar Nipponbare)所表示的蛋白质、或者由在序列编号2的氨基酸序列中缺失、取代、附加和/或插入了 I个〜数个氨基酸残基后的氨基酸序列构成，并且具有作为14-3-3蛋白与成花素结合的功能的蛋白质。本发明中的14-3-3蛋白优选为至少含有序列编号2中的第51〜227位的氨基酸序列，并且以第I〜5位中的I个氨基酸开始且以第230〜256位中的I个氨基酸结束的多肽片段，更优选为由序列编号2中的第I〜235位的氨基酸序列构成的多肽片段。
[0120]另外，水稻GF14b含有序列编号4所示的氨基酸序列（0s04g0462500) (GenbankAccession No. AK071822 :源自 Oryza sativa Japonica group cultivar Nipponbare)所表示的蛋白质、或者由在序列编号4的氨基酸序列中缺失、取代、附加和/或插入了 I个〜数个的氨基酸残基后的氨基酸序列构成，并具有作为14-3-3蛋白与成花素结合的功能的蛋白质。水稻GF14b的氨基酸序列与GF14c的氨基酸序列相比较有六个残基发生偏离。序列编号2中的第51〜227位的氨基酸序列相当于序列编号4中的第57〜233位的氨基酸序列，序列编号2中的以第I〜5位中的I个氨基酸开始并以第230〜256位中的I个氨基酸结束的氨基酸序列，相当于序列编号4中的以第7〜11位中的I个氨基酸开始并以第236〜262位中的I个氨基酸结束的氨基酸序列。
[0121]在本发明中，bZIP转录因子没有特别限定，可以例举出水稻OsFDl或者拟南芥的FD (Genbank Accession No. AB105823)，优选水稻OsFDl。水稻OsFDl含有序列编号3所示的氨基酸序列（0s09g0540800 :源自 Oryza Sativa Japonica group cultiva r Nipponbare)(TIGR水稻基因组注释数据库中被特定的Rice genome annotation locus No. L0C_0s09g36910. I)所表示的蛋白质、或者由在序列编号3的氨基酸序列中缺失、取代、附加和/或插入了 I个〜数个氨基酸残基后的氨基酸序列构成且作为bZIP转录因子发挥功能的蛋白质。本发明中的bZIP转录因子优选为至少含有序列编号3中的第189〜195位的氨基酸序列，且以第182〜188位中的I个氨基酸开始并以第195位的氨基酸结束的多肽片段，更优选为由序列编号3中的第187〜195位的氨基酸序列构成的多肽片段。另外，优选在该多肽片段中第192位的丝氨酸被磷酸化。该丝氨酸的磷酸化被认为是14-3-3蛋白与bZIP转录因子相结合所必需的。
[0122]上述成花素、14-3-3蛋白以及bZIP转录因子结合而形成成花素激活复合物。对于成花素和14-3-3蛋白的结合而言，认为序列编号I中的第62〜132位的氨基酸序列的区域或者具有序列编号I以外的氨基酸序列的成花素的与上述区域相当的区域，和/或序列编号2中的第200〜227位的氨基酸序列的区域或者具有序列编号2以外的氨基酸序列的14-3-3蛋白的与上述区域相当的区域很重要。另外，对于14-3-3蛋白和bZIP转录因子的结合而言，序列编号2中的第51〜227位的氨基酸序列的区域或者具有序列编号2以外的氨基酸序列的14-3-3蛋白的与上述区域相当的区域，和/或序列编号3中的第189〜195位的氨基酸序列的区域或者具有序列编号3以外的氨基酸序列的bZIP转录因子的与上述区域相当的区域很重要，这在本发明中是显而易见的。
[0123]进而，在这些区域中，对于成花素和14-3-3蛋白的结合而言，认为序列编号I中的 D62、M63、R64、P96、T98、F103、R132的氨基酸或者具有序列编号I以外的氨基酸序列的成花素的与上述氨基酸相当的氨基酸，和/或序列编号2中的F200、D201、1204、E212、Y215、R226、D227的氨基酸或者具有序列编号2以外的氨基酸序列的14_3_3蛋白的与上述氨基酸相当的氨基酸很重要。另外，对于14-3-3蛋白和bZIP转录因子的结合而言，序列编号2中的K51、R58、F121、R131、L224、D227的氨基酸或者具有序列编号2以外的氨基酸序列的14-3-3蛋白的与上述氨基酸相当的氨基酸很重要，这在本发明中是显而易见的。
[0124]在本发明中，所谓的“相当于序列编号X中的特定的氨基酸（例如D62等）的蛋白质的部位”，是以除了序列编号X中的特定的氨基酸（例如D62)的部位以外，还包括在具有序列编号X以外的氨基酸序列且具有与序列编号X的蛋白质等价的功能的蛋白质中的、相当于上述特定的氨基酸（例如D62)的部位的含义进行使用。例如，所谓的“相当于序列编号2中的F200、D201、I204、E212、Y215及R226的14-3-3蛋白的部位”，是指除了序列编号2中的F200、D201、I204、E212、Y215及R226的部位以外，还包括具有序列编号2以外的氨基酸序列的14-3-3蛋白的与上述氨基酸相当的氨基酸、例如水稻GF14b的F206、D207、I210、E218、Y221 及 R232(相当于水稻 GF14c 的 F200、D201、1204、E212、Y215 及 R226)。
[0125]对成花素激活复合物在成花中的作用机制进行说明（参照图15)。14-3-3蛋白作为从叶子输送到茎顶端的成花素的衔接物（adaptor)而发挥作用。一般认为当成花素进入茎顶端的细胞内时，成花素首先在细胞质内与14-3-3蛋白结合。在此阶段，OsFDl在茎顶端细胞中被表达，该成花素和14-3-3蛋白的复合物从细胞质进入核内，并与bZIP转录因子结合从而形成成花素激活复合物，并且，该成花素激活复合物停留在核内。当这一系列的工序开始时，成花素激活复合物在核内积累。之后，成花素激活复合物将引起成花诱导的成花相关基因（例如0sMADS15基因）的转录激活。在上述作用机制中，成花素在茎顶端细胞的细胞质内被14-3-3蛋白捕获，并且，通过bZIP转录因子而使成花素和14-3-3蛋白的复合物被高效地输送至核内，以便将成花诱导所需的基因的转录激活。另外，本发明中的基于成花素激活复合物的成花相关基因的转录激活，被认为是通过成花素激活复合物向C-box DNA的结合而进行的。所谓的“C-box DNA”由GACGTC(序列编号10)的碱基序列所表示，并且存在于成花相关基因的启动子区中。推测成花素激活复合物是在成花相关基因的C-box上形成稳定的复合物，从而将成花相关基因的转录激活。
[0126]在本发明中，成花素、14-3-3蛋白、bZIP转录因子、它们的变异型蛋白质、成花素与14-3-3蛋白的复合物、14-3-3蛋白与bZIP转录因子的复合物、以及作为这三者的复合物的成花素激活复合物，既可以是从细胞、组织等分离提纯后的状态，也可以是将编码蛋白质的基因导入酵母或大肠杆菌等的宿主细胞而将该蛋白质在细胞内表达的状态。另外，本发明还涉及编码这些蛋白质的多核苷酸。也可以根据宿主细胞的表达系统而对这些蛋白质附加不影响蛋白质的功能程度的肽片段。例如在使用大肠杆菌的表达系统的情况下，源自大肠杆菌表达质粒的肽片段（GPGHM)被附加在蛋白质的N末端。
[0127]成花素和14-3-3蛋白的复合物或者14-3-3蛋白和bZIP转录因子的复合物可以通过使两种蛋白质以分离提纯后的状态接触、或者在生物体内接触来制备。同样地，作为三者的复合物的成花素激活复合物，也可以通过使三种蛋白质或者上述两者的复合物中的任一种与剩余的蛋白质以分离提纯后的状态接触、或者在细胞等的生物体内接触来制备。 [0128](成花素激活复合物或者成花素的晶体的制备方法）
[0129]首先，制备蛋白质溶液。使蛋白质存在于由缓冲液、盐、还原剂等制成的溶液中。缓冲液、盐、还原剂只要是对蛋白质的立体结构没有影响的物质，便可以是任何物质，例如，缓冲液可以例举出ImM〜500mM的Na-HEPES、磷酸钠、磷酸钾、Tris-HCl等，盐可以例举出ImM〜IM的氯化钠、氯化锂、氯化镁等,还原剂可以例举出O. ImM〜IOmM的β -巯基乙醇、二硫苏糖醇（DTT)等。另外，蛋白质溶液中还可以含有二甲亚砜（DMSO)或者乙二醇。含蛋白质的溶液的pH为4〜11,优选pH为6〜9。该蛋白质溶液或成花素溶液既可以直接使用于晶化中，也可以根据需要进一步添加防腐剂或者稳定剂、表面活性剂等之后使用于晶化中。
[0130]作为将蛋白质（多肽）晶化的方法，可以使用蒸汽扩散法、分批法（batchmethod)、透析法等通常的蛋白质晶化方法。另外，在蛋白质的晶化中，蛋白质的浓度、盐浓度、pH、沉淀剂的种类、温度等的物理和化学因素的确定很重要。
[0131]所谓的“蒸汽扩散法”，是将含有沉淀剂的蛋白质溶液的液滴放置于装有含更高浓度的沉淀剂的缓冲液（外液）的容器中并密封后静置的方法。根据液滴的放置方式，有悬滴法（hanging drop method)和坐滴法（sitting drop method),本发明中可以采用任一种方法。悬滴法是将蛋白质溶液的小液滴配置于盖玻片上，并且，使盖玻片在储液器内倒置并将储液器密封的方法。另一方面，坐滴法是在储液器内部设置适宜的液滴座，将蛋白质溶液的小液滴配置在液滴座上，并利用盖玻片等将储液器密封的方法。在任一方法中，均在储液器中的溶液（储液器溶液）中含有沉淀剂。也可以在蛋白质的小液滴中适当地含有少量的沉淀剂。
[0132]蒸汽扩散法中使用的储液器溶液（也称为“沉淀剂溶液”）是由缓冲液、沉淀剂、盐等制成的溶液。缓冲液、沉淀剂、盐只要是能够有効地制备晶体的物质，便可以是任何物质，例如，缓冲液可以从PH4〜10、5mM〜200mM的Na_HEPES、磷酸钠、磷酸钾、Tris_HCl、乙酸钠、柠檬酸、卡可基酸（cacodylic acid)等中进行选择，沉淀剂可以从分子量为550〜20000且容量百分比为5〜35的聚乙二醇（PEG)、0. 2M〜2M的硫酸铵、容量百分比为5〜35的MPD(甲基戊二醇）、0. 2M〜2M的酒石酸铵或容量百分比为5〜35的异丙醇、或者这些物质的组合中进行选择，盐可以从0. 2M〜4M的氯化钠、氯化锂、氯化镁等中进行选择。储液器溶液的成分并不限于上述情况。
[0133]本发明的成花素激活复合物的晶体可以如下那样进行制备。将成花素和14-3-3蛋白加以混合，并透析至含有IOmM〜50mM NaCl的ImM〜50mM Tris-HCl缓冲液（pH为6. 5〜8. 5)中，由此来调制复合物试样。将蛋白质溶液（蛋白质浓度为5mg/mL〜40mg/mL)和沉淀剂溶液（O. 05M〜O. IM HEPES (pH为6. 5〜8. 5)、O. OlM〜O. 4M硫酸铵、容量百分比为15〜30的PEG (分子量为2000〜4000))进行混合，并使用坐滴法在4°C〜20°C的条件下进行成花素和14-3-3蛋白的复合物的晶化。在约I〜3周后得到成花素和14-3-3蛋白的复合物的单晶体。将得到的单晶体进行回收，并在含有容量百分比为15〜30的乙二醇、ImM〜5mM的bZIP转录因子的沉淀剂溶液（O. 05M〜O. IM HEPES (pH为6. 5〜8. 5)、O. OlM〜O. 4M(优选为O. 15M〜O. 25M)硫酸铵、容量百分比为15〜30 (优选为23〜27)的PEG (分子量为2000〜4000))中培养10〜20分钟，由此能够得到适于X射线晶体结构分析的成花素激活复合物的晶体。
[0134]本发明的成花素激活复合物的晶体优选可以如下那样进行制备。将成花素和14-3-3蛋白以摩尔比I : I〜2 (更优选为I : I. 5)进行混合，并透析至含有20mM NaCl的IOmM Tris-HCl缓冲液（pH为7. 5)中，由此来调制复合物试样。将I μ I蛋白质溶液（蛋白质浓度为10mg/mL)和I μ I沉淀剂溶液(O. IM HEPES (pH为7. 5)、0· 2M硫酸铵、容量百分比为25的PEG 3350)进行混合，并使用坐滴法在4°C的条件下进行成花素和14_3_3蛋白的复合物的晶化。在约I〜3周后得到成花素和14-3-3蛋白的复合物的单晶体。将得到的单晶体进行回收，并在含有25%乙二醇、2mM bZIP转录因子的沉淀剂溶液（(O. IM HEPES(pH为7. 5)、0. 2M硫酸铵、容量百分比为25的PEG 3350)中培养10〜20分钟（更优选为15分钟），由此能够得到成花素激活复合物的晶体。
[0135]本发明中的成花素的晶体可以如下那样进行制备。将提纯后的成花素透析至含有IOmM〜50mM NaCl的ImM〜50mM Tris缓冲液（pH为5. 5〜7. 5)中，并浓缩至浓度成为5mg/mL〜40mg/mL。将得到的蛋白质溶液和沉淀剂溶液（O. OlM〜O. 5M(优选为O. 05M〜O. 15M)卡可基酸(pH为5. 5〜7. 5)、0· OlM〜O. 5M(优选为O. 15M〜O. 25M)酒石酸铵、容量百分比为10〜50 (优选为25〜35)的PEG (分子量为5000〜12000))进行混合，并使用坐滴法在4V〜20°C的条件下进行，由此能够在约O. 5天〜3天（优选为约I天）后得到适于X射线晶体结构分析的成花素激活复合物的晶体。
[0136]本发明中的成花素的晶体优选可以如下那样进行制备。将提纯后的成花素透析至含有20mM NaCl的IOmM Tris缓冲液（pH为7. 5)中，并浓缩至浓度成为5mg/ml。将得到的I μ I蛋白质溶液和I μ I沉淀剂溶液（O. IM卡可基酸（pH为6. 5)、0. 2M酒石酸铵、容量百分比为30的PEG 8000)进行混合，并使用坐滴法在4°C的条件下进行，由此能够在约O. 5天〜3天（优选为约I天）后得到适于X射线晶体结构分析的成花素激活复合物的晶体。
[0137]在本发明中，优选得到具有如下那样的品质的晶体，S卩，在供于X射线晶体结构分析时仅赋予至少IOA以下的分辨率、优选为4.0A以下的分辨率、更优选为3.4A以下的分辨率、进而更优选为2.8 A以下的分辨率、尤其优选为2.4 A以下的分辨率的品质(((Introduction to Protein Structure 蛋白质的结构入门》Carl Brandon&JohnTooze,胜部幸辉等翻译，教育社，1992年，276-277页）。
[0138](成花素激活复合物或成花素的晶体）[0139]本发明的成花素激活复合物或成花素的晶体实质上不含杂质，并且即使再次溶解时也具有活性。作为杂质，可以举出GST、成花素或成花素激活复合物的分解产物、大肠杆菌固有的蛋白质等。
[0140]本发明的成花素激活复合 物的晶体的空间群为P1、P6522或者P4，晶格常数为a=74A 〜158 A、b=64 A 〜158 A、c=96 A 〜500A、α =66。〜90。、β =85。〜90。、Y =75。〜120°。根据本发明得到的晶体的分辨率为约I.OA〜约3.5 Α，是足以实施X射线晶体结构分析的品质和大小。
[0141]本发明的成花素激活复合物的晶体优选为从以下选择的晶体：
[0142](I)晶体的空间群为Ρ1，晶格常数为a=74A〜79Α、b=94A〜99A、c=96A~10lA、α = 66° 〜70°、β = 85° 〜90°、Y = 75° 〜79° 的晶体；
[0143](2)晶体的空间群为Ρ6522,晶格常数为a=125 A〜135 A、b=125 A~135 A、c=340 A-344 A > α = 90°、β =90°、Y =120。的晶体；
[0144]⑶晶体的空间群为Ρ4，晶格常数为a=153 A〜158 A、b=153 Α~158Α、c=495 Α~498 A、ct =90°、β = 90°、γ =90° 的晶体。
[0145]本发明的成花素激活复合物的晶体更优选为从以下选择的晶体：
[0146]〔成花素激活复合物I〕晶体的空间群为Ρ1，晶格常数为a=76.7A、b=96.6A、c 二 99.5 A、α = 68.2°、β = 87.9°、γ = 77.9° 且分辨率为 2.4 A 的晶体；
[0147]〔成花素激活复合物2〕晶体的空间群为P1，晶格常数为a=76.8A、b=97.3 A、c=99.8A, α = 68. 1° , β = 87.8° , y = 77.9° 且分辨率为 2.2 A 的晶体；
[0148]〔成花素激活复合物3〕晶体的空间群为Pl，晶格常数为a=76.2A、b=96.1 A、c=99.1 A, α = 68.2°、β = 88. 6°、γ = 77.8° 且分辨率为 2.8 A 的晶体；
[0149]〔成花素激活复合物4〕晶体的空间群为P6522，晶格常数为a=129.0A、b=129.0A、c=342.0A、α = 90°、β = 90°、Y = 120。且分辨率为 2.85 A的晶体；
[0150]〔成花素激活复合物5〕晶体的空间群为P4,晶格常数为a=l55.9A、b=l55.9A、c=496.4A、α = 90°、β = 90°、Y = 90。且分辨率为 2.96A的晶体。
[0151]本发明的成花素的晶体的空间群为P63，晶格常数为a=65 A〜67A、b=65 A〜67A、c=58A〜61A、α = 90°、β = 90°、Y = 120°。根据本发明得到的晶体的分辨率为约1.θΑ〜约3.5·Α(优选为1.0 A〜1.5 A )，是足以实施X射线晶体结构分析的品质和大小。
[0152]本发明的成花素的晶体优选为从以下选择的晶体：
[0153]〔成花素I〕晶体的空间群为Ρ63,晶格常数为a=65.9A、b=65.9 A、c二59.8 A、α=90°、β = 90°、γ = 120°且分辨率为1.3 A的晶体；
[0154]〔成花素2〕晶体的空间群为P6522,晶格常数为3=66.(^4=66.(^4=60.21α =90°、β = 90°、Y = 120°且分辨率为1.4 A的晶体；
[0155]上述成花素的晶体的分辨率优良，并且，对上述晶体进行X射线结构分析而得到的立体结构信息适合使用于基于计算机的对接仿真（docking simulation)等。
[0156](X射线晶体结构分析）
[0157]作为明确蛋白质（多肽）的立体结构的方法而最普遍进行的是X射线晶体结构分析。其是将蛋白质晶化，对其晶体照射单色化后的X射线，从而根据得到的X射线的衍射像来明确蛋白质中的立体结构信息。立体结构信息中包括电子密度图和原子坐标，原子坐标可以通过该技术领域公知的方法进行分析而得到（D.E. McRee, Practical ProteinCrystallography, Academic Press, San Diego (1993))。
[0158]X射线晶体结构分析包括：对晶体照射X射线而得到衍射数据的工序、通过得到的衍射数据的分析而得到蛋白质（多肽）的电子密度的工序、以及通过得到的电子密度的分析而得到蛋白质（多肽）的原子坐标的工序。
[0159]X射线晶体结构分析是使用实验室的X射线衍射仪或大型放射光设施（ESRF，APS，SPring-8, PF, ALS, CHESS, SRS, LLNL, SSRL, Brookhaven 等），通过振动照相法等并利用成像板或CCD照相机等的二维检测器而进行衍射数据的收集，并根据该数据得到电子密度，由此能够弄清楚原子坐标。
[0160]由于蛋白质的晶体因X射线照射而受到损伤从而衍射能力变差的情况较多，因此，优选利用低温测定来进行高分辨率的X射线衍射。所谓的“低温测定”，是将晶体急剧冷 却冻结至-173°C左右并在该状态下收集衍射数据的方法。一般而言，在蛋白质晶体的冻结中，出于防止因为冻结而导致晶体损坏的目的，想出了利用含有甘油等保护剂（防冻剂）的溶液进行处理等的方法。冻结晶体可以通过将浸泡在例如添加了保护剂的保存液中的晶体直接浸溃于液态氮中而使之瞬间冻结来制备。
[0161]通过利用数据处理软件对根据X射线衍射实验收集的衍射图像进行处理，能够算出由各个衍射斑点的指数和积分得到的衍射强度。通过使用这些衍射斑点的衍射强度和相位信息进行傅里叶逆变换而导出三维空间的电子密度。在衍射实验中，由于在原理上是无法测量电子密度的计算所需的各衍射斑点的相位信息，因此，为了得到电子密度，而利用分子置换法、重原子同晶置换法、多波长反常散射法（MAD法）或它们的改进方法来推定作为失去的信息的相位。
[0162]由这样得到的电子密度绘出电子密度图，根据该电子密度图并使用在图形工作站上运行的软件来构建三维模型。在构建了该模型之后，利用最小二乘法等进行结构的精密化，由此得到最终的蛋白质的原子坐标（立体结构坐标）。
[0163](成花素激活复合物或成花素的立体结构信息）
[0164]原子坐标是指将上述蛋白质的原子的位置以三维坐标的形式进行表示的数学坐标。原子坐标实质上是指根据构成化学结构的分子（原子）间的各距离而确定的空间配置。在将空间配置在计算机上作为信息进行处理时，将相对的配置作为某一坐标系中的特定坐标而数字信息化（称为“坐标化”）。这是在进行计算机处理时为了方便所必需的处理，原子坐标的本质如之前所示为根据各分子（原子）间相互的距离而确定的配置，应当理解为并非计算机处理时暂时被特定的坐标值。另外，在本说明书中，所谓的“原子坐标”是指关于构成物质（蛋白质、氨基酸等）的各个原子的坐标。
[0165]在本说明书中，将成花素激活复合物I的原子坐标表示于表I中，将成花素I的原子坐标表示于表2中。表I和2的数据依据蛋白质数据银行（PDB)的格式（http://www. wwpdb. org/documentation/format23/v2. 3. html)进行记载。另外，在本发明中，对于与本发明的多肽具有40%以上的同源性的蛋白质，也可以使用由上述电子密度或原子坐标所表示的立体结构信息，而以衍生物的形式得到在计算机上通过同源建模（hom*ologymodeling)等得到的原子坐标。[0166](调节植物的成花的物质的筛选方法)
[0167]通过选择在由成花素、14-3-3蛋白以及bZIP转录因子构成的成花素激活复合物中能够对各蛋白质的结合产生影响的物质（包括化合物）、具有能够竞争性地与结合部位结合的结构的物质（包括化合物），能够从大量物质中得到能够调节成花的物质。
[0168]作为本发明的筛选方法的一个形态，可以举出使用计算机设计和/或选择具有调节成花素激活复合物的活性的功能的候选物质，由此筛选出调节植物的成花的物质的方法(以下，也简称为“使用计算机的筛选方法”）。该筛选方法包括以下的工序：
[0169](a)将从本发明的成花素激活复合物或成花素的晶体中得到的立体结构信息存储在存储手段中的工序，
[0170](b)根据立体结构信息并利用导出手段而将三维立体结构模型导出的工序， [0171](C)在导出的三维立体结构模型中，利用计算手段计算出原子间距离的工序，
[0172](d)根据计算出的原子间距离，并利用计算手段而计算出能够增强和/或阻碍成花素与14-3-3蛋白的结合、和/或14-3-3蛋白与bZIP转录因子的结合的候选物质的立体结构信息，由此设计和/或选择候选物质的工序。
[0173]作为上述成花素激活复合物等的立体结构信息，可以使用各蛋白质的结合部位的原子坐标，可以利用各蛋白质的原子坐标的整体、包含结合部位在内的其派生物、以及它们的一部分。另外，在本发明中，也可以利用将结合部位的原子坐标在计算机上适宜地进行了改变后的信息，以便适于筛选。
[0174]在工序（a)和工序（b)中，通过将成花素激活复合物或成花素的立体结构信息中的原子坐标输入到表达分子的原子坐标的计算机程序运行的计算机或该计算机的存储介质中，能够详细地表达出各种蛋白质的三维化学相互作用的方式。表达分子的原子坐标的计算机程序在市场上大量有售，这些程序一般具备：分子的原子坐标的输入手段；根据立体结构信息并通过导出手段而将三维立体结构模型导出，并且将该坐标视觉性地表达在计算机图像中的手段；测量或计算被表达在计算机图像中的分子内的各原子间的距离或结合角等的手段；进行该坐标的追加修正的手段等。进而，还可以使用具备根据分子的坐标来计算分子的结构能的手段、考虑到水分子等的溶剂分子后计算自由能的手段的程序。由Accelrys公司市售的计算机程序InsightII或QUANTA适合用于本发明的筛选方法,但是，能够使用于本发明中的程序并不限于上述程序。
[0175]候选物质可以是公知或新型物质中的任一种，其结构、来源、物理性能等也没有特别限制，可以为天然化合物、合成化合物、高分子化合物、低分子化合物、肽、核酸类似物的任意一种。候选物质的立体结构的坐标化只要使用公知的程序即可，例如，作为将低分子化合物的立体结构坐标化的程序，可利用CORINA(http://www2. chemie. uni-erlangen.de/software/corina/index, html)、Concord(http ://www. tripos, com/sciTech/inSilicoDisc/chemlnfo/concord, html)、或者 Converter 等。
[0176]在工序（c)和（d)中，包括以下阶段：使候选物质的原子坐标与具有成花素、14-3-3蛋白、bZIP转录因子（或者，它们之中二者的复合物或成花素激活复合物）的结合部位的原子坐标在同一坐标系上重合，从而对两者的一致状态进行评价的阶段、或者根据成花素激活复合物等的原子坐标计算出原子间距离，并根据原子间距离来设计候选物质的阶段。这些阶段能够使用上述那样的市售软件包和能够运行该软件的计算机系统进行实施。
[0177]该计算机系统适宜地包括例如：保存化合物等物质的结构式的存储手段、将化合物等物质的立体结构坐标化的手段、保存化合物等物质的原子坐标的存储手段；保存工序(a)中所使用的各蛋白质的原子坐标的存储手段、保存评价结果的存储手段；显示各存储手段中的内容的手段；键盘等的输入手段、显示器等的显示手段、以及中央处理器等的运作目标软件所需的各种手段。
[0178]作为分析用软件，只要是能够在计算机上进行使候选物质与蛋白质对接(docking)的操作的软件,便可以使用任何软件,例如也可以使用DOCK、FlexX(Tripos公司)>LigandFit (Accelrys 公司)、Ludi (Accelrys 公司)等。此外，还可使用 InsightII 等的分子显示软件以对话的方式进行。此时，作为使用这些程序评价一致状态时的指标，可以任意选择使用复合物整体的自由能计算值、经验打分函数、形状的互补性的评价等。通过该指标，能够客观地评价结合的良好与否。
[0179]使用了成花素和成花素激活复合物等各种蛋白质的原子坐标的成花调节物质的设计或选择，能够在计算机上迅速地进行筛选。另外，对于通过利用计算机的筛选而选择的候选物质群而言，优选进行实验性评价。·
[0180]在上述使用计算机筛选调节植物的成花的物质的方法中，为了实验性评价上述候选物质的调节成花素激活复合物的作用的功能，候选物质优选合成或获得。候选物质只要使用公知的方法合成、或通过提纯等从生物体获得即可。
[0181]进而，通过将得到的候选物质供给于使用成花素等各种蛋白质的生物化学方法或生物学方法等而进行实验性评价，从而能够选择具有更有效地调节成花素激活复合物的作用的功能的物质，进一步能够选择调节成花的物质。
[0182]作为本发明的筛选方法的其他形态，可以举出通过生物化学方法或生物学方法来选择具有调节成花素激活复合物的作用的功能的物质（即，具有能够调节成花的功能的物质）的方法本身（以下，也仅称为“基于生物化学方法等的筛选方法”）。候选物质是否显示成花素激活复合物作用的调节功能，只要调查在向能够确认成花素激活复合物作用的调节功能的系统中添加和未添加该候选物质时，成花素激活复合物的作用是否具有差别、例如形成的成花素激活复合物的量是否有差别即可。所谓的“能够确认调节成花素激活复合物的作用的功能的系统”，例如是基于使成花素、14-3-3蛋白和/或bZIP转录因子接触的工序的系统，进一步可具体举出以下的工序：
[0183](I)使候选物质与成花素或14-3-3蛋白中的任一种接触，之后使候选物质与14-3-3蛋白或成花素接触的工序；或者
[0184](2)使候选物质与结合有或未结合有成花素的14-3-3蛋白或者bZIP转录因子中的任一种接触，之后使候选物质与bZIP转录因子或者结合有或未结合有成花素的14-3-3蛋白接触的工序。
[0185]所谓的“调节成花素激活复合物的作用的功能”，优选为增大和/或抑制成花素激活复合物的形成的功能。一般认为通过增大和/或抑制成花素激活复合物的形成，能够调节植物的成花，即能够加快和/或延迟成花。
[0186]上述使成花素、14-3-3蛋白和/或bZIP转录因子接触的工序能够通过在候选物质的存在下或不存在下进行酵母双杂交法、双分子荧光互补法等确认相互作用而进行，从而能够评价成花素激活复合物作用的调节功能。或者，成花素激活复合物作用的调节功能的评价能够通过下述那样而进行，即，将成花素或bZIP转录因子固定在平板上，并添加经荧光标记后的14-3-3蛋白和候选物质，从而测量平板的荧光强度。此外，在成花素激活复合物作用的调节功能的评价中，还可使用等温滴定量热仪（ITC)、表面等离子共振（SPR)等。
[0187]在具有成花素激活复合物作用的调节功能的物质（进而为调节成花的物质）的选择方法中，优选以成花素与14-3-3蛋白的结合部位、和/或14-3-3蛋白与bZIP转录因子的结合部位上的结合作为指标。所谓的“将这些结合部位上的结合作为指标”，是指对成花素激活复合物中的结合部位的结合状态进行确认。与候选物质的不存在下的情况相比，在候选物质的存在下的情况中，当结合被阻碍时能够将该候选物质作为具有抑制成花素激活复合物的形成的功能的物质来选择，当结合被促进时能够将该候选物质作为具有增大成花素激活复合物的形成的功能的物质来选择。
[0188]复合物中的结合部位上的结合状态的确认，能够通过NMR (核磁共振）法、荧光标记法等进行。
[0189]在NMR法中，例如在候选物质的存在下使稳定同位素标记后的成花素与未标记的14-3-3蛋白和bZIP转录因子结合的情况下，与候选物质不存在下的情况相比较，当成花素的NMR波谱在结合部位发生特异性变化时，能够确认候选物质对结合部位上的结合产生了影响。在成花素的NMR信号的全部残基的归属（例如成花素为Hd3a时，鉴别各NMR峰值源自Hd3a的哪个氨基酸）被确认的情况下，能够特定出结合了候选物质的氨基酸。
[0190]在荧光标记法中，只要使用例如使结合部位附近的氨基酸变异为半胱氨酸残基，并使其与半胱氨酸特异性作用的荧光试剂反应从而导入了荧光标记的物质即可。由于一般认为当结合状态发生变化时导入的荧光的强度也会发生变化，因此，能够根据候选物质的有无来确认该结合部位的结合状态。
[0191]NMR法可以通过将成花素、14-3-3蛋白以及bZIP转录因子溶解在溶液中并测量NMR波谱而进行。作为溶解成花素等的溶液，只要是能够测量NMR波谱的溶液，便可以是任何溶液，可使用含有DTT (二硫苏糖醇）、KC1 (氯化钾）,NaCl (氯化钠）、重水的缓冲液等。作为NMR测量法，优选使用同核多维NMR测量或者异核多维NMR测量等。例如，可以利用被称为1H-15NHSQC的NMR测量法进行。该测量是本领域普通技术人员已知的技术。1H-15NHSQC是蛋白质的肽键中的氢原子和氮原子的相关波谱，即1H-15N相关波谱，能够从源于主链的1H-15N信号得到各个残基的信息。通过该NMR测量方法，能够分析蛋白质等的目标高分子物质的立体结构，从而能够分析蛋白质的相互作用。
[0192]在本发明的筛选方法中，也可以将使用计算机的筛选方法和基于生物化学方法等的筛选方法加以组合进行使用。
[0193]进而，候选物质的调节植物的成花的功能、即加快和/或延迟成花的功能的评价，能够通过将候选物质施与植物体（例如从根部吸收候选物质、导入编码候选物质的基因等而制备转化体）来进行调查。
[0194](调节植物的成花的方法）
[0195]本发明还涉及调节植物的成花的方法。所谓的“调节成花”，是指加快和/或延迟成花。更详细而言，本发明涉及通过对下述I)和/或2)所示的任一个或多个结合部位施加影响、即调节该结合部位上的结合，而促进（增大）和/或抑制成花素激活复合物的形成，由此调节植物的成花的方法。
[0196]I)成花素与14-3-3蛋白的结合部位是相当于序列编号I中的D62、M63、R64、P96、T98、F103及R132的成花素的部位和相当于序列编号2中的F200、D201、I2 04、E212、Y215、R226及D227的14-3-3蛋白的部位。
[0197]2)14-3-3蛋白与bZIP转录因子的结合部位是相当于序列编号2中的K51、R58、F121、R131、L224及D227的14-3-3蛋白的部位和相当于序列编号3中的R189〜F195的bZIP转录因子的部位。
[0198]促进（增大）和/或抑制成花素激活复合物的形成的情况，例如可以例举出使成花素与14-3-3蛋白的结合部位和/或14-3-3蛋白与bZIP转录因子的结合部位发生变异的情况、或者将能够促进和/或抑制成花素与14-3-3蛋白的结合和/或14-3-3蛋白与bZIP转录因子的结合的物质施与植物体的情况等。 [0199]作为能够促进成花素与14-3-3蛋白的结合和/或14-3-3蛋白与bZIP转录因子的结合的物质，可以举出编码成花素、14-3-3蛋白或bZIP转录因子的基因本身。作为编码成花素、14-3-3蛋白或bZIP转录因子的基因，例如可以例举出编码水稻Hd3a(序列编号11)、水稻GF14b (序列编号14)、水稻GF14c (序列编号12)、水稻FDl (序列编号13)的基因。编码成花素、14-3-3蛋白或bZIP转录因子的基因也可以是对相当于序列编号I中的D62等的部位、相当于序列编号2中的F200等的部位、相当于序列编号R189〜F195的部位中的I个以上的结合部位发生了变异的蛋白质（变异型蛋白质）进行编码的基因。编码变异型蛋白质的基因可以通过使用本领域普通技术人员周知的定点突变法等的基因工程方法导入变异而制备。例如，可以通过组合PCR反应（聚合酶链式反应）、限制酶反应、连接反应等来制备编码变异型蛋白质的基因，具体而言，可以使用QuikChangeTM定点突变试剂盒(site-directed mutagenesis kit) (STRATAGENE公司)等的试剂盒。通过使上述基因在植物体内、优选为所期望的植物组织的细胞内、更优选为细胞器内（过量地）表达，能够促进成花素与14-3-3蛋白的结合和/或14-3-3蛋白与bZIP转录因子的结合，从而能够促进(加快）成花。
[0200]使基因（过量地）表达的方法没有特别限定，但是，一般采用通过基因工程方法将分离后的基因以能够表达的状态导入到植物细胞内等的公知方法。公知方法可以例举出将含有所希望的基因的重组载体（recombinant vector)导入到宿主中的方法。具体而言，可以举出原生质体共培养法或者叶盘法等利用土壤杆菌属细菌的感染的方法，聚乙二醇法，电穿孔法，显微注射法，基因枪法，脂质体法，使用适宜的载体系统的导入法等，只要根据宿主细胞的种类而选择最适的方法即可。另外，作为上述载体，可以举出质粒、噬菌体、粘粒等，但是，上述载体并没有特别限定，只要根据宿主细胞的种类适宜地选择即可。另外，作为宿主细胞，可以使用广泛种类的植物，也可以是原生质体、细胞、愈伤组织、器官叶、种子、胚芽、花粉、卵细胞、接合子等能够增殖的植物材料，花、果实、叶、根、插枝等植物体的一部分坐寸ο
[0201]“促进成花”是指缩短营养生长时间而加快花的形成，一般认为通过促进成花能够使农作物和园艺作物的收获时期改变（一般是提前），从而能够谋求育种的効率化或农作物和园艺作物的收量增加。另外，由于可以推测花或种子的形成能力正常，因此，能够迅速地生产植物的种子。[0202]另外，作为能够抑制成花素与14-3-3蛋白的结合和/或14-3-3蛋白与bZIP转录因子的结合的物质，可以举出例如具有结合能的成花素、14-3-3蛋白、bZIP转录因子的多肽片段、或者成花素等的工程蛋白质（engineered protein)且阻碍正常蛋白质的功能的工程蛋白质。通过将表达上述蛋白质的基因导入到植物体中，能够阻碍成花素激活复合物的形成，从而能够调节成花。此处所谓的“工程”，是指使上述蛋白质所具有的特征性氨基酸序列区域的任意区域完全缺失的情况、和相对于上述序列区域的特定部位而缺失、取代和/或插入I个〜数个氨基酸残基的情况。工程蛋白质中包括变异型蛋白质。
[0203]改变编码各蛋白质的基因的方法只要通过现有公知的方法进行即可，并没有特别限定。即，只要通过如上所述那样利用PCR法向碱基序列导入变异、或者使用公知的定点突变法（Kunkel et al. :Proc. Natl. Acad. Sci. USA, vol. 82. p488_(1985))、市售的试剂盒(例如Quikchange定点突变试剂盒：STRATAGENE公司）等进行即可。
[0204]工程蛋白质（包括多肽)相对于从野生型基因中得到的蛋白质起显性作用，抑制目标基因的转录从而阻碍目标基因的表达。因此，当使用改造型基因时，能够阻碍野生型基因所具有的本来的功能而使其功能缺损，从而能够生产将成花抑制了的转化体。因此，能够 减少生产将成花抑制了的转化体所需的工夫。
[0205]工程蛋白质的导入方法能够通过表达上述基因的方法而进行。
[0206]另外，使植物体的内在性蛋白的结合部位变异或者将蛋白质剔除（knockout)，可以通过利用公知的反义法、基因打靶法、基因破坏型标记法等的方法等进行（Kem pin etal. Nature389 :802-803. 1997)。
[0207]反义法是下述那样的方法，S卩，构建含有适当的启动子和配置于其下游的反向的目标基因（反义DNA)的载体，并将该载体导入到植物中，由此来抑制目标基因的表达的方法。基因打靶法是通过同源重组而在目标基因的一部分中插入其他的DNA从而将目标基因剔除的方法。基于基因破坏型标记法的本发明的方法，是将T-DNA或转座子（transposon)任意地插入基因组中，并利用PCR筛选目标基因破坏株的方法。
[0208]“抑制成花”是指延长营养生长期从而延迟花的形成，一般认为通过这样，与野生型的植物体相比植物体变大（Developmentl35，767-774 (2008) doi :10. 1242/dev. 008631、Fig3E)。即，通过抑制成花，能够提供每个个体的生物量增产了的植物体。所谓的“生物量增产”，是指与野生型相比每个个体的总重量变大，也包括植物体的一部分组织特异性地变大，而其他的组织与野生型同等的情况。植物生物量由于是使用太阳能而将大气中的二氧化碳固定而生成，因此，能够作为所谓的碳中和能量进行掌握。增加植物的生物量具有保护地球环境、防止地球变暖、降低温室效应气体排出的效果。另外，对于除了有关花芽形成的器官（花或种子）以外的其他部分被作为粮食等使用的植物而言，通过抑制成花，能够使植物体变大，从而能够谋求增加每个个体的农作物和园艺作物的收量。
[0209](转化体)
[0210]本发明还涉及导入了所希望的基因的转化体、或者所希望的基因被破坏了的转化体。本发明的转化体包括在上述调节植物的成花的方法中得到的物质。所谓的“转化体”不仅包括植物个体还包括细胞、组织、器官、原生质体。另外，成为转化对象的生物也没有特别限定，可以举出各种微生物（包括大肠杆菌等）或植物。另外，在选择启动子或载体时，也可以将动物、昆虫作为转化的对象。另外，此处所说的转化体中还包括导入了本发明所涉及的基因的植物、或者与其具有相同性质的该植物的后代或它们的组织。上述转化体可以使用在上述调节植物的成花的方法的项目中说明的方法进行制备（生产）。
[0211]实施例
[0212]以下，为了加深对本发明的理解，根据实施例和实验例具体地进行说明，当然，这些实施例和实验例并非对本发明的范围进行限定。另外，在以下的实施例中使用的Hd3a、GF14、FDl全部为源自水稻的蛋白质。在表示各蛋白质时，存在记载为“Os”的情况和不记载为“Os”的情况，但是，在以下的实施例中所使用的蛋白质均源自水稻。
[0213]首先，实施例中所使用的质粒的制备方法如下所示。
[0214]通过RT-PCR 将 Hd3a(0s06g0157700)、0sGF14 (0sGF14a :0s08g0480800、OsGF14b ：0s04g0462500、0sGF14c :0s08g0430500、0sGF14d :0sllg0546900、0sGF14e :0s02g0580300、0sGF14f ：0s03g0710800, 0sGF14g ：OsO Ig0209200, 0sGF14h ：Os 11g0609600)、OsFDl (0s09g0540800)的全长cDNA进行克隆（cloning)。利用通常方法将编码区域PCR扩 增，并导入至pENTR/D-T0P0克隆载体（Invitrogen),由此得到了入门克隆（entry clone)。
[0215]向0sGF14、OsFDl、Hd3a的氨基酸的取代或缺失的导入，利用KOD FX DNApolymerase (Τ0Υ0Β0)并通过PCR而进行。将PCR扩增片段导入pENTR/D-TOPO克隆载体，从而得到了入门克隆。
[0216]将源自玉米的泛素启动子（ubiquitin promoter)、NOS终止区（Miki and Shimamoto，Plant Cell Physiol. 45，490 (2004) ·)、以及 T7 标签区或 HA 标签区与 attR 重组区(Nakagawa et al. 2007) 一起插入至pGreen II载体（Hellens et al. Plant Mol. Biol. 42,819(2000).)中，由此制备了 pGII pUbq GW-T7 和 pGII pUbq HA-Gff0
[0217]根据文献记载制备了 pUbq:Hd3a-mCherry表达载体（非专利文献2)、pHd3a:Hd3a_GFP 以及 prolC:Hd3a_GFP 双兀载体（Tamaki et al. , Science316,1033(2007))。按照 Tamaki et al.，Science316，1033 (2007) 2007 且使用变异型 Hd3a cDNA而制备了 pro IC: Hd3a (R64G) -GFP 双元载体和 pro IC: Hd3a (R64G/R132A) -GFP 双元载体。为了制备其他的载体，通过基于Gateway BP clonase II (Invitrogen)的Gateway重组法,将pENTR D-T0P0载体中的变异型Hd3a基因、变异型0sGF14基因、变异型OsFDl基因转化成各种载体。
[0218]这些载体在酵母双杂交实验（yeast two-hybrid assay)(实施例8、9)中有时被包含在 pBTM116_GW和 pVP16_GW 中，另外，在瞬时表达实验（transient expression assay)(实施例 11、12)中有时被包含在 pGII pUbq GW-T7、pGII pUbq HA-GW、p35S_GFP_GW、p35S-mCerulean-GW、p35S_Vn_GW、p35S-Vc_GW、p35S_GW_Vn、p35S-Gff-Vc 以及 pUbq-GW 中，在转基因植物（实施例10、13-1、13-2)的制备中有时被包含在P2K-GW双元载体和pANDARNAi 载体（Miki and Shimamoto 2004)中。通过 PCR 而使 SV40NLS 与 GF14b 以及 GF14e 融八
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[0219](实施例I)三种蛋白质的相互作用的确认
[0220](I)通过体外GST pull-down实验对三种蛋白质的相互作用进行了确认。
[0221]对插入了编码序列编号I所示的全长Hd3a(l〜179残基）的cDNA、编码序列编号2所示的全长GF14c (I〜256残基)的cDNA的质粒进行限制酶处理，使限制酶处理后的片段与编码GST的多核苷酸融合并导入到载体中。将该载体导入到大肠杆菌中，在大肠杆菌内表达了 GST融合GF14c蛋白质或者GST融合Hd3a蛋白质。在对大肠杆菌进行了培养之后，对大肠杆菌进行离心并回收，从溶解溶液中将GST融合GF14c蛋白质或者GST融合Hd3a蛋白质分离提纯。
[0222]将分离提纯后的GST融合GF14c蛋白质或者GST融合Hd3a蛋白质各IOnmol与10 μ I的谷胱甘肽-琼脂糖凝胶（Glutathione Sepharose) 4B树脂（GE Healthcare)进行培养，从而使各多肽与树脂结合。之后，用含有50mM KClUmM DTT的磷酸缓冲液（pH为6. 8)对树脂进行清洗，将未与树脂结合的游离的GST融合蛋白质除去。作为阴性对照（negativecontrol)而使用了使分离提纯后的GST蛋白质与树脂结合后的物质。向结合了 GST_GF14c蛋白质、GST-Hd3a蛋白质或者GST蛋白质的3种树脂中加入Inmol的分离提纯后的各蛋白质（OsFD I为序列编号3的第147〜195位的区域且被导入了 S192E的变异的蛋白质，Hd3a为全长且未融合任何GST)，并在室温下培养了 15分钟。之后，用含有50mM KClUmM DTT的磷酸缓冲液（pH为6. 8)对树脂进行清洗，将未与树脂结合的游离的GST-GFHc多肽除去。利用含有50mM谷胱甘肽、50mM KClUmM DTT的磷酸缓冲液（pH为6. 8)对结合后的各蛋白质进行洗脱，并通过SDS聚丙烯酰胺电泳进行了确认。
[0223]结果如图2所示。由于在Hd3a与OsFDl (FDl)之间未发现相互作用，而在Hd3a与GF14c之间和GF14c与OsFDl之间发现了相互作用，因此，认为Hd3a与OsFDl通过GF14c结八
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[0224](2)关于Hd3a与GF14c的相互作用，使用NMR进行了确认。利用含有IOOmMKCl、ImM DTT、7%重水的50mM磷酸缓冲液（pH为6. 8)将15N稳定同位素标记后的Hd3a蛋白质调制成最终浓度为O. 2mM。之后，对于仅调制好的Hd3a蛋白质溶液、和在Hd3a蛋白质溶液中以摩尔比I : O. 5加入了未进行稳定同位素标记的GF14c蛋白质的混合溶液的各溶液，对15N-HSQC NMR波谱进行了测量，并对波谱进行了比较。NMR测量在温度30°C下进行，并且使用f*cker公司制AV500NMR装置进行。
[0225]结果如图3所示。由于因GF14c的结合而Hd3a的NMR波谱发生变化，因此，可以确认Hd3a与GF14c发生结合。另外，由于局部地观察到NMR信号的移动（图3中的放大图，Hd3a R64、M63等），因此，确认到部位特异性的结合。
[0226](实施例2)成花素激活复合物的晶体的制备
[0227]对插入了编码序列编号I所示全长Hd3a (I〜179残基）中的6〜170残基的cDNA、编码序列编号2所示全长GF14c (I〜256残基）中的I〜235残基的cDNA的质粒进行限制酶处理，使限制酶处理后的片段与编码GST的多核苷酸融合并导入到载体中，并且将该载体导入到大肠杆囷中。在大肠杆囷中表达GST融合后的Hd3a蛋白质、GST融合后的GF14c蛋白质。在对大肠杆菌进行了培养之后，对大肠杆菌进行离心并回收，并从溶解溶液中提纯蛋白质。之后，利用SDS-聚丙烯酰胺电泳法（SDS-PAGE)进行了分析，结果得知蛋白质的纯度为95%以上。对于编码序列编号3中所示的全长OsFDl (I〜195残基）中的187〜195残基的多肽，通过进行化学合成而进行了调制。
[0228]将得到的Hd3a、GF14c以摩尔比I : 1.5进行混合，并将其透析至含有20mMNaCl的IOmM Tris-HCl缓冲液（pH为7. 5)中，由此制备了复合物试样。复合物的晶化是将I μ I蛋白质溶液（蛋白质浓度为10mg/mL)和I μ I沉淀剂溶液(O. IM HEPES (pH为7. 5)、0· 2M硫酸铵、25% PEG 3350)加以混合，并使用坐滴法在4°C下进行。在约2周后得到O. ImmXO. Imm的单晶体。将得到的Hd3a-GF14c复合物晶体进行回收，并利用含有25%乙二醇、2mM OsFDl多肽的上述沉淀剂溶液培养15分钟，由此制备了 Hd3a、GF14c以及OsFDl的成花素激活复合物的晶体。
[0229]得到的晶体为以下5种。
[0230]〔成花素激活复合物I〕晶体的空间群为P1，晶格常数为a=76.7A、b=96.6A、c=99.5A, α = 68.2°、β = 87. 9°、Y = 77.9°，分辨率为 2.4 A的晶体；
[0231]〔成花素激活复合物2〕晶体的空间群为P1，晶格常数为a=76.8A，b=97.3 A、c=99.8A, α = 68. 1°、β = 87.8° , γ = 77.9°，分辨率为 2.2A的晶体；
[0232]〔成花素激活复合物3〕晶体的空间群为P1，晶格常数为a=76.2A、b=96.1 A、c-99.1 Α, α = 68.2°、β = 88.6°、Y = 77. 8°，分辨率为 2.8 A 的晶体；
[0233]〔成花素激活复合物4〕晶体的空间群为P6522,晶格常数为a=129.0A、b=129.·0A、c=342.0A、α = 90°、β = 90°、Y = 120。，分辨率为 2.85 A 的晶体；
[0234]〔成花素激活复合物5〕晶体的空间群为P4,晶格常数为a=l55.9A、b=l55.9A、c=496.4A、α = 90°、β = 90°、Y = 90。，分辨率为 2.96 A的晶体。
[0235](实施例3)关于成花素激活复合物的晶体的X射线结构分析
[0236]对于得到的晶体，在放射光科学研究设施Photon Factor的BL5A光束线中使用CCD检测器对其X射线衍射像进行了测量。根据得到的衍射像而得到了成花素激活复合物的原子坐标。
[0237]收集X射线衍射数据，并进行了各个衍射斑点的指数标定（indexing)和衍射强度的计算。利用分子置换法从得到的衍射强度和搜索模型（search model)确定了相位角。使用这些衍射斑点的衍射强度和相位角，并通过傅里叶逆变换而导出了电子密度图。根据得到的电子密度图而构建了原子坐标。
[0238]具体而言，使用HKL2000对得到数据进行处理，并通过SCALEPACK进行了缩放。作为搜索模型，利用分子置换法而确定了成花素的晶体结构。使用CNS和REFMAC以2.4 A对得到的模型进行了精密化。在各精密化之后，使用COOT并根据作为电子密度图的2Fo-Fcmap对得到的模型进行了补正。
[0239]将由上述成花素激活复合物I的晶体得到的原子坐标表示在表I中。另外，将根据原子坐标构建的立体结构模型示于图I和图4中。可知GF14c特异性地识别OsFDl的被磷酸化后的S192(pS192)。
[0240](表I)成花素激活复合物的原子坐标
[0241]ATOMIN ALAA2 31.1421.296 -20.9841.00 51.41NATOM2CA ALAA 2 32.2681.774-21.8091.00 52.40C
ATOM3CB ALAA 2 33.5132.058 -20.9371.00 52.30C
ATOM4C ALAA2 32.5930.828 -22.9751.00 52.86C
ATOM5O ALAA2 33.229-0.202 -22.7721.00 53.40O
ATOM6N ARGA 3 32.0841.185-24.1691.00 53.41N
ATOM7CA ARGA 3 32.440 0.674 -25.5581.00 53.27C
ATOM8CB ARGA 3 33.537-0.414-25.6471.00 53.41C
ATOM9CG ARGA 3 34.919 0.203 -25.8661.00 54.57C
ATOM10CD ARGA 3 34.8061.706-25.5821.00 55.37C
ATOM11NE ARGA 3 35.9002.301 -24.8181.00 55.34N
ATOM12CZ ARGA 3 35.7303.286 -23.9371.00 55.19C
ATOM13NHl ARGA3 34.5113.759 -23.6911.00 56.49N
ATOM14NH2ARGA3 36.7693.802 -23.2971.00 53.48N
ATOM15C ARGA3 31.3000.588-26.6191.00 53.10C
ATOM16O ARGA3 31.3371.366 -27.5651.00 53.15O
ATOM17N ALAA4 30.324-0.339 -26.5241.00 52.96N
ATOM18CA ALAA 4 30.299-1.577 -25.6651.00 52.78C
ATOM19CB ALAA4 31.747-2.092 -25.3331.00 53.18C
ATOM20C ALAA4 29.374-1.880 -24.4291.00 52.15C
ATOM21O ALAA4 29.576-2.972 -23.8611.00 52.35O
ATOM22N GLUA5 28.389-1.057 -23.9921.00 50.91N
ATOM23CA GLUA 5 27.7980.159 -24.6171.0049.94C
ATOM24CB GLUA 5 26.390-0.151 -25.1491.00 50.00C
ATOM25CG GLUA 5 25.7231.029-25.8471.00 50.89C
ATOM26CD GLUA 5 26.0691.106 -27.3221.0051.65C
ATOM27OEl GLUA5 26.8871.977 -27.7041.0051.42O
ATOM28OE2GLUA5 25.5300.274-28.0891.00 50.98O
ATOM29C GLUA5 27.6331.316-23.6161.0048.74C
ATOM30O GLUA5 27.2611.100-22.4461.0049.06O
ATOM31N ASNA6 27.8442.541 -24.0971.0046.60N
ATOM32CA ASNA 6 27.7503.746 -23.2741.00 44.70C
ATOM33CB ASNA6 28.6164.837 -23.8891.0045.55C
ATOM34CG ASNA 6 30.0494.466 -23.8771.00 45.64C
ATOM35ODl ASNA6 30.4013.481 -23.2741.00 46.78O
ATOM36ND2ASNA6 30.8885.234 -24.5441.0049.27N
ATOM37C ASNA6 26.3514.279 -22.9411.0042.93C
ATOM38O ASNA6 26.1704.970-21.9321.00 42.13O
ATOM39N VALA7 25.3843.957 -23.8011.0041.06N
ATOM40CA YALA7 23.9774.191 -23.5491.00 38.54C
ATOM41CB VALA7 23.0893.803 -24.8101.00 39.03C
ATOM42CGl VALA7 21.6163.714-24.4581.00 35.44C
ATOM43CG2VALA7 23.2974.811 -25.9481.00 37.57C
[0242]ATOM44C VALA7 23.5573.384 -22.3261.00 37.95CATOM45O VALA7 22.7843.858-21.4871.00 37.36O
ATOM46N TYRA8 24.0572.156 -22.2441.00 37.25N
ATOM47CA TYRA8 23.6711.234-21.178 1.00 37.26C
ATOM48CB TYRA8 24.172-0.198 -21.4751.00 37.87C
ATOM49CG TYRA8 23.687-1.173 -20.4311.00 39.00C
ATOM50CDl TYRA8 24.479-1.480-19.3041.00 39.44C
ATOM51CEl TYRA8 24.011-2.338-18.3031.0039.53C
ATOM52CZ TYRA8 22.747-2.885-18.4161.00 39.69C
ATOM53OH TYRA8 22.270-3.732-17.434 1.00 39.52O
ATOM54CE2 TYRA8 21.943-2.595-19.5311.0040.46C
ATOM55CD2TYRA8 22.414-1.744 -20.5301.00 37.47C
ATOM56C TYRA8 24.2191.756-19.8341.00 36.60C
ATOM57O TYRA8 23.4931.838-18.8371.00 36.56O
ATOM58N META9 25.4982.123-19.8351.00 35.58N
ATOM59CA META9 26.1492.696-18.657 1.00 35.28C
ATOM60CB META9 27.6562.799-18.867 1.00 35.75C
ATOM61CG META9 28.3101.415-18.894 1.00 37.42C
ATOM62SD META9 27.8040.449-17.4351.0040.70S
ATOM63CE META9 28.8291.257-16.1811.00 38.72C
ATOM64C META9 25.5394.018-18.2531.00 34.23C
ATOM65O META9 25.3944.300-17.0661.00 34.05O
ATOM66N ALAA10 25.1234.795-19.2511.00 33.43N
ATOM67CA ALAA10 24.3486.007-19.023 1.00 32.18C
ATOM68CB ALAA10 24.1286.764 -20.3191.0031.28C
ATOM69C ALAA10 23.0205.721-18.3191.0031.48C
ATOM70O ALAA10 22.6746.406-17.3801.0031.40O
ATOM71N LYSA11 22.2854.716-18.7651.00 30.72N
ATOM72CA LYSA11 21.0394.362-18.1121.00 30.94C
ATOM73CB LYSA11 20.2573.345-18.9481.0031.29C
ATOM74CG LYSA11 19.3523.969-19.9971.00 32.38C
ATOM75CD LYSA11 19.4153.150-21.2601.00 37.15C
ATOM76CE LYSA11 18.0302.818-21.7901.0038.03C
ATOM77NZ LYSA11 18.1081.757 -22.8591.0040.35N
ATOM78C LYSA11 21.2353.845-16.6781.00 30.04C
ATOM79O LYSA11 20.4424.182-15.7831.0028.77O
ATOM80N LEUA12 22.2923.049-16.4901.0029.31N
ATOM81CA LEUA12 22.6732.490-15.1841.00 29.37C
ATOM82CB LEUA12 23.9751.667-15.2621.0029.16C
ATOM83CG LEUA12 24.2400.361 -14.4651.0028.96C
ATOM84CDl LEU A12 25.7370.233-14.1391.0027.79C
ATOM85CD2LEUA12 23.4370.206-13.1961.0027.82C
ATOM86C LEUA12 22.9183.650-14.2561.00 28.79C
ATOM87O LEUA12 22.4003.646-13.1681.00 28.52O
[0243]ATOM88N ALAA1323.6994.633 -14.7231.00 29.20NATOM89CA ALAA1324.1125.813-13.9361.0028.98C
ATOM90CB ALAA1325.1776.594-14.6941.0028.06C
ATOM91C ALAA1322.9136.707-13.6031.0029.17C
ATOM92O ALAA1322.8187.290-12.5151.00 29.82O
ATOM93N GLUA1421.9766.792-14.5381.0028.60N
ATOM94CA GLUA 1420.7057.464-14.2811.0028.31C
ATOM95CB GLUA1419.8077.409-15.5231.0027.41C ATOM96CG GLUA 1418.5278.220-15.3351.0026.34C
ATOM97CD GLUA 1417.6408.210-16.5871.00 27.63C
ATOM98OEl GLUA1417.6747.209-17.3341.00 26.33O
ATOM99OE2GLUA1416.9609.231 -16.8341.0025.29O
ATOM100C GLUA1419.9226.888-13.0911.00 28.14C
ATOM101O GLUA1419.2987.603 -12.2971.0028.64O
ATOM102N GLNA1519.9195.581 -12.9871.0028.97N
ATOM103CA GLNA 1519.1804.951-11.9161.0029.37C
ATOM104CB GLNA 1518.8883.521 -12.2701.00 30.40C
ATOM105CG GLNA 1517.6913.381-13.1911.00 33.15C
ATOM106CD GLNA 1517.3631.959-13.3171.00 39.98C
ATOM107OEl GLNA1516.7681.369-12.4071.00 43.52O
ATOM108NE2GLNA1517.8271.341 -14.4051.00 43.02N
ATOM109C GLNA1519.8835.051 -10.5851.00 28.96C
ATOMHOO GLNA1519.2245.155 -9.5551.0029.05O
ATOM111N ALAA1621.2145.064-10.6261.0028.35N
ΑΓΟΜ112CA ALAA1622.0535.274 -9.4551.00 28.31C
ATOM113CB ALAA1623.4834.797 -9.7631.00 27.43C
ATOM114C ALAA1622.0426.752 -9.0721.00 28.31C
ATOM115O ALAA1622.6307.143 -8.0671.0029.06O
ATOM116N GLUA1721.3967.579 -9.9061.0027.98N
ATOM117CA GLUA1721.3719.012 -9.7161.0027.51C
ATOM118CB GLUA1720.4819.394 -8.5301.0027.15C
ATOM119CG GLUA1719.0838.755 -8.5911.0029.51C
ATOM120CD GLUA 1718.1549.239 -7.477 1.0031.66C
ATOM121OEl GLUA1718.6099.968 -6.5491.00 35.44O
ATOM122OE2GLUA1716.9588.875 -7.5441.0037.86O
ATOM123C GLUA1722.7939.542 -9.5491.00 26.63C
ATOM124O GLUA1723.08110.355 -8.6611.0025.95O
ATOM125N ARGA1823.6859.050-10.4111.00 25.69N
ATOM126CA ARGA 1825.0519.549-10.4671.0024.20C
ATOM127CB ARGA 1826.0468.388 -10.3701.0024.16C
ATOM128CG ARGA 1826.2017.717 -8.956 1.00 23.12C
ATOM129CD ARGA 1827.3746.698 -8.976 1.00 24.79C
ATOM130NE ARGA1828.0506.725 -7.694 1.00 30.66N
ATOM131CZ ARGA1829.3157.080 -7.4551.00 30.81C
[0244]ATOM132NHl ARGA18 29.7287.082 -6.202 1.00 30.96NΑΓΟΜ133NH2ARGA18 30.1697.381 -8.412 1.00 27.92N
ATOM134C ARGA18 25.17710.306-11.7811.00 23.24C
ATOM135O ARGA18 25.6499.774-12.7631.00 22.77O
ATOM136N TYRA19 24.73011.561-11.7891.00 23.88N
ATOM137CA TYRA19 24.47612.285-13.047 1.0023.92C
ATOM138CB TYRA19 23.43213.381 -12.8591.00 22.80C
ATOM139CG TYRA19 22.09912.793 -12.469 1.0022.81C
ATOM140CDl TYRA19 21.32112.033 -13.3821.00 23.79C
ATOM141CEl TYRA19 20.09711.475-12.9771.0020.54C
ATOM142CZ TYRA19 19.68911.689-11.6731.00 20.82C
ATOM143OH TYRA19 18.546 11.213-11.182 1.0023.47O
ATOM144CE2TYRA19 20.43012.422-10.7971.0021.90C
ATOM145CD2TYRA19 21.62612.961-11.1951.0022.69C
ATOM146C TYRA19 25.65212.767-13.8541.0025.21C
ATOM147O TYRA19 25.53912.891 -15.0701.00 24.56O
ATOM148N GLUA20 26.75613.102-13.1801.00 26.24N
ATOM149CA GLUA20 27.94613.546-13.874 1.00 28.42C
ATOM150CB GLUA20 28.92014.334-12.9481.00 28.86C
ATOM151CG GLUA20 29.02413.861 -11.5591.00 32.87C
ATOM152CD GLUA20 27.88414.329-10.656 1.00 36.93C
ATOM153OEl GLUA20 27.75315.551 -10.4761.00 38.18O
ATOM154OE2GLUA20 27.14013.460-10.1051.00 39.32O
ATOM155C GLUA20 28.63512.398-14.6151.00 28.85C
ATOM156O GLUA20 29.28512.618-15.6481.0029.50O
ATOM157N GLUA21 28.45711.182-14.1011.00 28.80N
ATOM158CA GLUA21 28.898 9.992-14.7581.0028.82C
ATOM159CB GLUA21 28.953 8.807-13.7841.00 28.64C
ATOM160CG GLUA21 30.107 8.911 -12.7501.00 29.59C
ATOM161CD GLUA21 30.100 7.807-11.7031.0029.30C
ATOM162OEl GLUA21 31.0807.732-10.9101.0024.26O
ATOM163OE2GLUA21 29.1306.996-11.6941.0028.47O
ATOM164C GLUA21 27.9469.710-15.9111.0029.54C
ATOM165O GLUA21 28.3729.190-16.9261.00 30.15O
ATOM166N META22 26.66510.028-15.7541.00 30.02N
ATOM167CA META22 25.685 9.864-16.8511.00 30.51C
ATOM168CB META22 24.26010.095-16.3451.00 30.31C
ATOM169CG META22 23.151 9.651-17.2931.0028.65C
ATOM170SD META22 21.63610.483-16.8051.0028.69S
ATOM171CE META22 20.5189.886-18.0961.00 27.45C
ATOM172C META22 26.01410.840-18.0031.0031.74C
ATOM173O META22 25.94110.459-19.1571.0031.73O
ATOM174N VALA23 26.39912.078-17.6721.00 32.77N
ATOM175CA VALA23 26.92013.045-18.6591.00 34.35C
[0245]ATOM 176CB VALA23 27.33114.407-17.9881.00 34.05CATOM 177CGl VALA23 28.24715.224-18.8931.00 33.74C
ATOM 178CG2VALA23 26.13615.226-17.6101.0031.25C
ATOM 179C VALA23 28.14812.490-19.4341.00 36.17C
ATOM180O VALA23 28.25912.673 -20.6641.00 36.03O
ATOM181N GLUA24 29.06411.845-18.7001.00 37.14N
ATOM182CA GLUA 24 30.31411.325-19.267 1.00 38.46C
ATOM183CB GLUA24 31.22110.755-18.1851.0038.31C
ATOM184CG GLUA 24 32.03011.807-17.4731.0040.46C
ATOM185CD GLUA 24 32.66311.261-16.229 1.0042.78C
ATOM186OEl GLUA24 32.54210.040-15.9971.00 44.23O
ATOM187OE2GLUA24 33.25512.054-15.4661.00 45.77O
ATOM188C GLUA24 30.08410.263 -20.3141.00 38.30C
ATOM189O GLUA24 30.66210.312-21.3931.00 38.21O
ATOM190N TYRA25 29.2539.294-19.9831.00 39.41N
ATOM191CA TYRA25 28.9358.243 -20.9271.0040.26C
ATOM192CB TYRA25 28.0667.175 -20.2731.00 40.98C
ATOM193CG TYRA25 28.8266.354-19.2581.0041.75C
ATOM194CDl TYRA25 29.8865.527-19.6481.00 43.31C
ATOM195CEl TYRA25 30.5974.753-18.6991.0045.47C
ATOM196CZ TYRA25 30.2264.808 -17.3521.0044.52C
ATOM197OH TYRA25 30.9044.057-16.4071.0044.37O
ATOM198CE2TYRA25 29.1715.626-16.9541.0044.28C
ATOM199CD2TYRA25 28.4786.387-17.9121.00 42.63C
ATOM200C TYRA25 28.2778.819-22.1701.00 40.77C
ATOM201O TYRA25 28.7878.643 -23.2781.00 41.00O
ATOM202N META26 27.1739.542-21.9691.0040.99N
ATOM203CA META26 26.37810.111 -23.0511.0040.66C
ATOM204CB META26 25.21410.915-22.4811.0040.03C
ATOM205CG META26 24.00110.087-22.1211.0038.31C
ATOM206SD META26 23.7038.720-23.2651.00 38.47S
ATOM207CE META26 23.3529.554-24.8171.00 37.55C
ATOM208C META26 27.19910.987 -23.9761.0041.33C
ATOM209O META26 26.89011.118-25.1531.0041.27O
ATOM210N GLUA27 28.23911.594-23.4281.0042.51N
ATOM211CA GLUA27 29.12812.460-24.1751.0044.03C
ATOM212CB GLUA27 30.03213.181 -23.2061.0044.67C
ATOM213CG GLUA27 30.59614.441 -23.7251.0046.54C
ATOM214CD GLUA27 30.50615.513-22.6831.00 52.21C
ATOM215OEl GLUA27 29.82616.540 -22.9341.00 53.16O
ATOM216OE2GLUA27 31.09215.313-21.5951.00 54.39O
ATOM217C GLUA27 30.01111.686 -25.1431.00 44.94C
ATOM218O GLUA27 30.35512.194-26.2171.0045.01O
ATOM219N LYSA28 30.39610.474 -24.7441.0045.46N[0246]ATOM 234 〇 VALA 29 27.914 9.697-29.689 1.0{M8.74 O ATOM 235 Z ALAA 30 270085 11.112-27.938 1.0049.45 Z ATOM 236 CA ALAA 30 27.739 12.296-28.767 100 50.67 O ATOM 237 CB ALAA 30 27312 13.497-27.929 1.00 50.46 C ATOM 23000 >M.» 30 28.996 12.584-29.6M 100 51.85 C ATOM 239 O ALAA 30 28.878K0027-30.822 1.00 51.61 O ATOM 240 N LYSA 31 30.184 12.535-28.999 1.00 5305 Z ATOM 241 CA LYSA 31 3L450 12.615-29.746 1.00 54.38 O ATOM 242 era LYSA 31 32.663 12.8s .28.832 1.00 53.90 n ATOM 243 CG LYSA 31 32.466 13.894-27.739 1.00 53.39 O ATOM 244 CD LYSA 31 33.430 15052-27.856 1.00 54.25 O ATOM 245 CR LYSA 31 33.605 15.731-26.501 1.00 54.26 n ATOM 246 ZN LYSA 31 34.469 16.949126.557 1.00 55.33¾ ATOM 247 C LYSA 31 31.651 11.305-3P501 LOO 55.91 n ATOM 248 O LYSA 31 32.257 10.371-29.978 too^aO ATOM 249 ^ ALAA 32 31.119 11.238.31.721 1.00 57.41 Z ATOM 250 〇A ALAA 32 31.300 1009OO—32.623 1.00 58.77 C ATOM 251 πω ALAA 32 32.75OC5020 33工仁 1.00 58.96 O ATOM 252 O >l>a 32 30.877 8.754-32.046 1.00 59.88 O ATOM 253 O ALAA 32 31.732 7.958-31.627 1.00 60.29 O ATOM 254 N VALA 33 Wsg 327.31.983 1.00 60.79 Z ATOM 255 CA VALA 33 28.969 7.162-31.964 1.00 6137 O ATOM 256 S VALA 33 29.249 6.278-30.671 1.00 61.32 n ATOM 257 CGl VALA 33 29.638 4.846-31.088 1.00 61.59 O ATOM 258 002 VAL A 33 Ws 亡 1.00 61.62 O ATOM 259 O VALA 33 27.467 7.163-32.356 1.00 61.53 n ATOM 260 O VALA 33 27.016 8.075-33067 100 61.52 O ATOM 261 N ASPA 34 26.722 6.171 -31.843 一oo2g7¾ ATOM 262 0> ASPA 3办 25.481 5.621-32.456 1.00 61.57 Π ATOM 263 CB ASPA 34 24.575 4.991-31.394 1.00 61.59 C
〔02 s
31ATOM264CG ASPA 3423.5304.026 -31.9881.00 62.07C
ATOM265ODl ASPA 3422.8074.376 -32.9621.0060.00O
ATOM266OD2ASPA 3423.4222.904-31.4421.0062.52O
ATOM267C ASPA 3424.6586.498 -33.4181.0061.55C
ATOM268O ASPA 3424.2387.619-33.0731.0061.02O
ATOM269N ALAA 3524.4175.902 -34.6011.0061.53N
ATOM270CA ALAA 3523.7436.475 -35.8101.00 60.98C
ATOM271CB ALAA 3522.2786.951-35.5171.00 60.93C
ATOM272C ALAA 3524.5357.521 -36.6241.00 60.42C
ATOM273O ALAA 3524.1497.839 -37.7551.0060.77O
ATOM274N GLUA 3625.6428.023 -36.0591.00 59.44N
ATOM275CA GLUA 3626.3869.199-36.5751.00 5·7.64C
ATOM276CB GLUA 3627.0498.914-37.9501.00 58.12C
ATOM277CG GLUA 3628.1317.785 -37.9641.00 59.12C
ATOM278CD GLUA 3629.4468.151 -37.2251.0061.44C
ATOM279OEl GLUA 3629.7319.360 -37.0401.00 62.03O
ATOM280OE2GLUA 3630.2017.224 -36.8351.0061.40O
ATOM281C GLUA 3625.51710.485 -36.5741.00 57.20C
ATOM282O GLUA 3625.60911.313-37.4961.00 57.40O
ATOM283N GLUA 3724.71410.615-35.5031.00 55.67N
ATOM284CA GLUA 3723.66711.642-35.2091.00 54.74C
ATOM285CB GLUA 3722.83512.092-36.4401.00 54.84C
ATOM286CG GLUA 3721.60913.018-36.1501.00 55.03C
ATOM287CD GLUA 3720.94113.673 -37.4151.00 54.66C
ATOM288OEl GLUA 3720.04514.538-37.2601.00 54.60O
ATOM289OE2GLUA 3721.28513.349 -38.5611.00 52.44O
ATOM290C GLUA 3722.77810.893 -34.2111.00 53.03C
ATOM291O GLUA 3722.2699.819-34.5141.00 52.57O
ATOM292N LEUA 3822.62411.442-33.0071.0051.75N
ATOM293CA LEUA 3821.89710.775 -31.9091.0049.64C
ATOM294CB LEUA 3821.88911.659-30.6611.0048.68C
ATOM295CG LEUA 3823.21512.203 -30.1531.0046.66C
ATOM296CDl LEUA 3823.00313.033 -28.8891.0044.02C
ATOM297CD2LEUA 3824.20011.053 -29.9061.0045.72C
ATOM298C LEUA 3820.45910.429 -32.2661.0049.03C
ATOM299O LEUA 3819.79711.199 -32.9541.0049.25O
ATOM300N THRA 3919.9799.285 -31.7871.0048.01N
ATOM301CA THRA 3918.5588.941 -31.8971.00 47.72C
ATOM302CB THRA 3918.3217.412-31.7281.0047.77C
ATOM303OGl THRA 3918.2797.055 -30.3391.0049.74O
ATOM304CG2THRA 3919.4296.609 -32.4261.0047.70C
ATOM305C THRA 3917.7309.784 -30.8901.0046.99C
ATOM306O THRA 3918.29410.564 -30.1171.0046.46O
ATOM307N VALA 4016.4059.650 -30.9221.0045.78N
[0248]ATOM 308CA VALA 4015.545 10.347 -29.9741.0045.05CATOM 309CB VALA 4014.050 9.978 -30.1941.0045.37C
ATOM 310CGl VALA 4013.211 10.217-28.9251.0044.78C
ATOM 311CG2 VALA 4013.475 10.739 -3 1.4001.00 46.76C
ATOM 312C VALA 4015.934 9.983 -28.5411.0044.37C
ATOM313O VALA 4015.945 10.844 -27.6691.0044.38O
ATOM314N GLUA 4116.245 8.701 -28.3261.0043.51N
ATOM315CA GLUA 4116.471 8.125 -27.0161.0042.45C
ATOM316CB GLUA 4116.549 6.601 -27.1081.00 42.74C
ATOM317CG GLUA 4115.819 5.890-25.9631.00 44.25C
ATOM318CD GLUA 4116.554 4.670-25.4141.0046.85C
ATOM319OEl GLUA 4116.092 4.146-24.3741.00 48.10O
ATOM320OE2GLUA 4117.582 4.243 -25.9951.00 46.85O
ATOM321C GLUA 4117.757 8.640-26.4091.0041.18C
ATOM322O GLUA 4117.815 8.917-25.2311.0040.81O
ATOM323N GLUA 4218.777 8.758-27.2451.0040.58N
ATOM324CA GLUA 4220.101 9.192 -26.8401.0040.30C
ATOM325CB GLUA 4221.147 8.711-27.8691.00 39.93C
ATOM326CG GLUA 4221.170 7.185 -28.0431.0041.19C
ATOM327CD GLUA 4221.903 6.712-29.3071.0041.83C
ATOM328OEl GLUA 4222.154 7.526 -30.2281.0042.42O
ATOM329OE2GLUA 4222.235 5.508 -29.3601.00 44.31O
ATOM330C GLUA 4220.174 10.707-26.6551.0038.94C
ATOM331O GLUA 4220.853 11.195 -25.7571.00 39.38O
ATOM332N ARGA 4319.504 11.433-27.5471.00 37.84N
ATOM333CA ARGA 4319.360 12.898 -27.5001.00 36.31C
ATOM334CB ARGA 4318.592 13.353 -28.7741.00 36.17C
ATOM335CG ARGA 4317.812 14.692-28.7651.0036.14C
ATOM336CD ARGA 4316.285 14.462 -28.7021.00 37.17C
ATOM337NE ARGA 4315.636 14.743 -29.9691.00 38.59N
ATOM338CZ ARGA 4314.326 14.660-30.2011.00 39.53C
ATOM339NHl ARGA 4313.458 14.298 -29.2551.0038.75N
ATOM340NH2ARGA 4313.877 14.960-31.4041.0042.59N
ATOM341C ARGA 4318.690 13.339-26.1681.00 35.25C
ATOM342O ARGA 4319.160 14.277 -25.4951.00 34.29O
ATOM343N ASNA 4417.620 12.638 -25.8051.00 33.98N
ATOM344CA ASNA 4416.929 12.821 -24.5221.00 34.18C
ATOM345CB ASNA 4415.597 12.058 -24.4611.00 33.84C
ATOM346CG ASNA 4414.595 12.478 -25.5501.0036.36C
ATOM347ODl ASNA 4414.786 13.457-26.2801.00 36.37O
ATOM348ND2ASNA 4413.500 11.723 -25.6441.00 38.59N
ATOM349C ASNA 4417.755 12.416-23.2941.00 33.21C
ATOM350O ASNA 4417.659 13.073 -22.2811.00 34.01O
ATOM351N LEUA 4518.531 11.337-23.3681.00 32.70N[0249]ATOM352CA LEUA 45 19.38910.934 -22.2341.0031.96C
ATOM353CB LEUA 4519.9429.496 -22.3871.00 32.56C
ATOM354CG LEUA 4519.0688.220 -22.2231.0031.94C
ATOM355CDl LEUA 4518.8327.908 -20.7711.0028.49C
ATOM356CD2LEUA 4519.7377.042 -22.8861.00 30.96C
ATOM357C LEUA 4520.53611.926 -22.0071.00 31.51C
ATOM358O LEUA 4520.97612.117-20.8721.0031.71O
ATOM359N LEUA 4621.00912.578 -23.0661.00 30.36N
ATOM360CA LEUA 46 22.10813.550 -22.8931.0029.84C
ATOM361CB LEUA 4622.85213.821 -24.2021.0029.01C
ATOM362CG LEUA 4623.86114.969-24.1701.00 30.98C
ATOM363CDl LEUA 4625.26814.568 -23.7121.00 30.06C
ATOM364CD2LEUA 4623.90515.611-25.5411.00 32.70C
ATOM365C LEUA 4621.57814.839 -22.2571.0029.20C
ATOM366O LEUA 4622.21215.399-21.3331.0028.76O
ATOM367N SERA 4720.42415.307 -22.7531.0028.03N
ATOM368CA SERA 4719.73016.450 -22.1391.00 27.01C
ATOM369CB SERA 4718.43716.825 -22.8641.0026.74C
ATOM370OG SERA 4717.97918.044-22.3151.0026.28O
ATOM371C SERA 4719.43116.220-20.6441.00 26.03C
ATOM372O SERA 4719.73817.067-19.8211.00 26.81O
ATOM373N VALA 4818.83715.083 -20.3111.0025.21N
ATOM374CA VALA 4818.54014.749-18.9111.00 24.32C
ATOM375CB VALA 4817.76613.440-18.7821.00 25.52C
ATOM376CGl VALA 4817.66013.026-17.2961.00 24.25C
ATOM377CG2VALA 4816.34813.563 -19.4241.0024.49C
ATOM378C VALA 4819.80914.660-18.0361.00 24.00C
ATOM379O VALA 4819.75514.992-16.8731.00 23.22O
ATOM380N ALAA 4920.91014.188-18.6011.00 23.19N
ATOM381CA ALAA 4922.14514.036-17.8701.0024.08C
ATOM382CB ALAA 4923.21413.414-18.7321.0023.44C
ATOM383C ALAA 4922.53315.401 -17.4341.00 24.13C
AlOM384O ALAA 4922.56715.660-16.2391.0024.39O
ATOM385N TYRA 5022.74616.287-18.4131.0025.06N
ATOM386CA TYRA 5023.15317.684-18.1861.0025.83C
ATOM387CB TYRA 5023.46118.396-19.5161.0026.94C
ATOM388CG TYRA 5024.89418.215-19.9681.0028.23C
ATOM389CDl TYRA 5025.94518.923-19.3541.00 29.40C
ATOM390CEl TYRA 5027.27018.745-19.7821.0028.53C
ATOM391CZ TYRA 5027.53017.872-20.8201.00 29.16C
ATOM392OH TYRA 50 28.83017.671 -21.2461.0031.59O ATOM393CE2TYRA 5026.49717.167-21.4451.00 26.43C
ATOM394CD2TYRA 5025.20617.333 -20.9951.0026.81C
ATOM395C TYRA 5022.17418.519-17.3951.00 25.71C
[0250]ATOM396O TYRA 50 22.60019.366-16.612 1.0025.06 OATOM397N LYSA 51 20.87118.298-17.622 1.0025.89N
ATOM398CA LYSA 51 19.802 18.963-16.877 1.00 26.78 C
ATOM399CB LYSA 51 18.43218.541 -17.398 1.00 27.63 C
ATOM400CG LYSA 51 17.331 19.499-17.049 1.00 32.69 C
ATOM401CD LYSA 51 15.954 18.804-17.076 1.00 39.31 C
ATOM402CE LYSA 51 14.83519.786-17.455 1.00 39.24C
ATOM403NZ LYSA 51 14.19220.563 -16.328 1.0043.60N
ATOM404C LYSA 51 19.86618.609-15.413 1.0026.25C
ATOM405O LYSA 51 19.55219.430-14.565 1.0027.41O
ATOM406N ASNA 52 20.25817.389-15.089 1.0026.07N
ATOM407CA ASNA 52 20.317 17.030-13.677 1.00 26.95 C
ATOM408CB ASNA 52 20.147 15.552-13.505 1.0026.29 C
ATOM409CG ASNA 52 18.717 15.136-13.577 1.0026.71 C
ATOM410ODl ASNA 52 18.22914.781 -14.636 1.00 28.41O
ATOM411ND2ASNA 52 18.02615.173-12.441 1.0025.98N
ATOM412C ASNA 52 21.59417.493 -12.970 1.00 27.53C
ATOM413O ASNA 52 21.56417.834-11.809 1.0029.47O
ATOM414N VALA 53 22.70517.502-13.694 1.0028.30N
ATOM415CA VALA 53 24.000 17.968-13.188 1.0028.91 C
ATOM416CB VALA 53 25.09017.613-14.219 1.0029.87C
ATOM417CGl VALA 53 26.49917.740-13.644 1.0028.44C
ATOM418CG2VALA 53 24.82516.196-14.678 1.0029.82C
ATOM419C VALA 53 23.95719.456-12.880 1.00 28.39C
ATOM420O VALA 53 24.23119.848-11.749 1.0029.93O
ATOM421N ILEA 54 23.59520.268-13.881 1.0026.69N
ATOM422CA ILEA 54 23.33521.703-13.734 1.0025.17C
ATOM423CB ILEA 54 23.04922.387-15.157 1.0025.33C
ATOM424CGl ILEA 54 23.46923.859-15.197 1.0025.49C
ATOM425CDl ILEA 54 25.00224.087 -14.984 1.00 22.53C
ATOM426CG2ILEA 54 21.55322.220-15.618 1.00 24.89C
ATOM427C ILEA 54 22.21922.078-12.732 1.00 24.89C
ATOM428O ILEA 54 22.36423.045-11.987 1.00 23.03O
ATOM429N GLYA 55 21.08921.367-12.750 1.00 24.17N
ATOM430CA GLYA 55 19.98821.668-11.815 1.0024.18 C
ATOM431C GLYA 55 20.39221.642-10.319 1.0024.09C
ATOM432O GLYA 55 19.85922.386 -9.489 1.00 24.43 O
ATOM433N ALAA 56 21.30720.765 -9.970 1.00 22.94 N
ATOM434CA ALAA 56 21.737 20.658 -8.615 1.0023.12 C
ATOM435CB ALAA 56 22.572 19.373 -8.411 1.00 22.78 C
ATOM436C ALAA 56 22.53621.932 -8.264 1.0023.18 C
ATOM437O ALAA 56 22.31322.527 -7.224 1.00 22.51 O
ATOM438N ARGA 57 23.34422.412 -9.191 1.00 23.41 N
ATOM439CA ARGA 57 24.157 23.618 -8.949 1.0024.55 C
[0251]ATOM440CB ARGA 57 25.324 23.714 -9.952 1.00 24.98CATOM441CG ARGA 57 26.568 22.884 -9.583 1.0025.30C
ATOM442CD ARGA 57 26.344 21.438 -9.849 1.00 24.89C
ATOM443NE ARGA 57 27.403 20.548 -9.371 1.00 26.25N
ATOM444CZ ARGA 57 27.349 19.231 -9.480 1.0029.96C
ATOM445NHl ARGA 57 28.350 18.489 -9.002 1.0028.96N
ATOM446NH2ARGA 57 26.264 18.641 -10.055 1.0031.37N
ATOM447C ARGA 57 23.307 24.876 -8.980 1.0024.41C
ATOM448O ARGA 57 23.566 25.806 -8.225 1.0023.64O
ATOM449N ARGA 58 22.295 24.894 -9.852 1.0023.57N
ATOM450CA ARGA 58 21.314 25.974 -9.907 1.0024.20C
ATOM451CB ARGA 58 20.326 25.805-11.092 1.00 24.04C
ATOM452CG ARGA 58 20.929 25.898 -12.524 1.0022.71C
ATOM453CD ARGA 58 19.917 26.594 -13.462 1.0025.20C
ATOM454NE ARGA 58 18.936 25.631 -13.924 1.00 28.50N
ATOM455CZ ARGA 58 17.709 25.925 -14.332 1.0029.65C
ATOM456NHl ARGA 58 17.251 27.169-14.360 1.00 28.87N
ATOM457NH2ARGA 58 16.944 24.945 -14.732 1.00 32.45N
ATOM458C ARGA 58 20.572 26.118 -8.561 1.0025.13C
ATOM459O ARGA 58 20.401 27.235 -8.073 1.00 27.04O
ATOM460N ALAA 59 20.175 24.990 -7.954 1.0025.05N
ATOM461CA ALAA 59 19.510 24.960 -6.658 1.00 24.81C
ATOM462CB ALAA 59 18.993 23.555 -6.369 1.0024.26C
ATOM463C ALAA 59 20.455 25.413 -5.539 1.00 25.09C
ATOM464O ALAA 59 20.083 26.207 -4.701 1.00 25.99O
ATOM465N SERA 60 21.662 24.895 -5.511 1.0025.20N
ATOM466CA SERA 60 22.626 25.319 -4.506 1.00 26.82C
ATOM467CB SERA 60 23.885 24.476 -4.579 1.0027.11C
ATOM468OG SERA 60 23.530 23.095 -4.540 1.00 24.94O
ATOM469C SERA 60 22.934 26.800 -4.620 1.0027.37C
ATOM470O SERA 60 22.864 27.501 -3.629 1.0029.01O
ATOM471N TRPA 61 23.207 27.283 -5.832 1.0027.88N
ATOM472CA TRPA 61 23.442 28.695 -6.091 1.0027.76C
ATOM473CB TRPA 61 23.730 28.939 -7.577 1.0028.59C
ATOM474CG TRPA 61 24.160 30.366 -7.883 1.00 28.91C
ATOM475CDl TRPA 61 25.448 30.835 -7.962 1.00 30.30C
ATOM476NEl TRPA 61 25.440 32.188 -8.240 1.0029.53N
ATOM477CE2TRPA 61 24.142 32.624 -8.309 1.0028.39C
ATOM478CD2TRPA 61 23.304 31.503 -8.095 1.0029.60C
ATOM479CE3TRPA 61 21.907 31.681 -8.138 1.0029.62C
ATOM480CZ3 TRPA 61 21.404 32.958 -8.381 1.0029.39C
ATOM481CH2TRPA 61 22.281 34.054 -8.607 1.00 30.44C
ATOM482CZ2TRPA 61 23.639 33.899 -8.563 1.0028.70C
ATOM483C TRPA 61 22.361 29.660 -5.574 1.0028.31C[0252]ATOM484O TRPA 61 22.701 30.662 -4.916 1.00 26.71O
ATOM485N ARGA 62 21.088 29.373 -5.894 1.00 28.54 N
ATOM486CA ARGA 62 19.925 30.124 -5.383 1.00 30.21 C
ATOM487CB ARGA 62 18.586 29.539 -5.884 1.00 29.86 C
ATOM488CG ARGA 62 18.349 29.651 -7.388 1.00 31.44 C
ATOM489CD ARGA 62 16.901 29.263 -7.746 1.00 32.27 C
ATOM490NE ARGA 62 16.742 27.815 -7.910 1.00 36.49 N
ATOM491CZ ARGA 62 16.783 27.175 -9.080 1.00 39.06 C
ATOM492NHl ARGA 62 16.630 25.852 -9.112 1.00 38.95 N
ATOM493NH2ARGA 62 16.973 27.854-10.218 1.0040.65N
ATOM494C ARGA 62 19.823 30.173 -3·.879 1.0030.43 C
ATOM495O ARGA 62 19.363 31.158 -3.346 1.0031.28 O
ATOM496N ILEA 63 20.161 29.075 -3.204 1.0031.52N
ATOM497CA ILEA 63 20.131 29.017 -1.759 1.00 32.53C
ATOM498CB ILEA 63 20.245 27.563 -1.261 1.00 32.14C
ATOM499CGl ILEA 63 18.852 26.957 -1.135 1.00 35.26C
ATOM500CDl ILEA 63 18.746 25.467 -1.598 1.00 37.56C
ATOM501CG2ILEA 63 20.936 27.486 0.081 1.00 32.79C
ATOM502C ILEA 63 21.231 29.938 -1.175 1.00 32.80C
ATOM503O ILEA 63 20.945 30.780 -0.342 1.00 32.60O
ATOM504N VALA 64 22.458 29.782 -1.653 1.00 33.55N
ATOM505CA VALA 64 23.613 30.552 -1.183 1.00 34.99 C
ATOM506CB VALA 64 24.931 29.946 -1.769 1.00 34.33 C
ATOM507CGl VALA 64 26.194 30.773 -1.417 1.00 33.35C
ATOM508CG2VALA 64 25.083 28.478 -1.308 1.00 34.45C
ATOM509C VAT.A 64 23.449 32.045 -1.508 1.00 36.91C
ATOM510O VALA 64 23.739 32.912 -0.676 1.00 37.99O
ATOM511N SERA 65 22.977 32.335 -2.720 1.00 37.95N
ATOM512CA SERA 65 22.719 33.693 -3.153 1.0038.60 C
ATOM513CB SERA 65 22.136 33.674 -4.552 1.00 38.02 C
ATOM514OG SERA 65 22.563 34.817 -5.247 1.0040.44 O
ATOM515C SERA 65 21.754 34.411 -2.225 1.00 39.20C
ATOM516O SERA 65 21.990 35.557 -1.823 1.00 39.43O
ATOM517N SERA 66 20.658 33.736 -1.902 1.00 39.78N
ATOM518CA SERA 66 19.651 34.278 -1.018 1.0040.56 C
ATOM519CB SERA 66 18.442 33.374 -0.995 1.0040.06 C
ATOM520OG SERA 66 17.637 33.748 0.108 1.00 43.13 O
ATOM521C SERA 66 20.145 34.508 0.418 1.0040.56C
ATOM522O SERA 66 19.760 35.476 1.052 1.0040.06O
ATOM523N ILEA 67 20.955 33.588 0.928 1.00 41.61N
ATOM524CA ILEA 67 21.656 33.784 2.189 1.0042.72C
ATOM525CB ILEA 67 22.503 32.533 2.605 1.00 42.91C
ATOM526CGl ILEA 67 21.637 31.264 2.636 1.0043.10C
ATOM527CDl ILEA 67 20.686 31.172 3.805 1.0046.49C
[0253]ATOM528CG2ILEA6723.189 32.7533.9551.0042.35CATOM529 C ILEA6722.549 35.0122.0411.0043.24C
ATOM530 O ILEA6722.526 35.9092.8871.0043.36O
ATOM531N GLUA6823.298 35.0800.9481.00 44.13N
ATOM532CA GLUA 6824.202 36.206 0.7471.00 45.71C
ATOM533CB GLUA6824.909 36.130-0.6031.0045.73C
ATOM534CG GLUA 6826.130 37.054-0.6541.0045.70C
ATOM535CD GLUA 6826.905 36.900-1.9161.0045.76C·
ATOM536OEl GLUA6827.251 35.739-2.2341.0043.89O
ATOM537OE2GLUA6827.159 37.933-2.5881.0046.83O
ATOM538C GLUA6823.563 37.5870.9361.0046.19C
ATOM539O GLUA6824.134 38.4321.6201.0046.58O
ATOM540N GLNA6922.393 37.8010.3361.0047.23N
ATOM541CA GLNA6921.687 39.095 0.3911.0048.23C
ATOM542CB GLNA6920.465 39.134-0.5551.0048.55C
ATOM543CG GLNA6920.639 38.516-1.9361.0051.26C
ATOM544CD GLNA6921.879 39.015-2.6861.00 56.39C
ATOM545OEl GLNA6922.361 38.350-3.6211.0057.11O
ATOM546NE2GLNA6922.407 40.178-2.2771.00 56.24N
ATOM547C GLNA6921.223 39.4221.8061.0047.95C
ATOM548O GLNA6921.434 40.5282.2831.0047.91O
ATOM549N LYSA7020.566 38.4532.4391.00 48.28N
ATOM550CA LYSA7020.156 38.4953.8371.0048.75C
ATOM551CB LYSA7019.756 37.0854.2591.00 48.73C
ATOM552CG LYSA7018.605 36.9845.2341.0050.18C
ATOM553CD LYSA7018.540 35.5905.8761.00 53.83C
ATOM554CE LYSA7018.679 34.4404.8551.00 56.98C
ATOM555NZ LYSA7017.421 34.1204.0821.00 57.40N
ATOM556C LYSA7021.283 39.0164.7541.00 49.29C
ATOM5.57O LYSA7021.088 39.9695.5071.0049.43O
ATOM558N GLUA7122.458 38.3964.6751.0049.94N
ATOM559CA GLUA7123.610 38.800 5.4921.0051.20C
ATOM560CB GLUA7124.688 37.708 5.4981.0051.16C
ATOM561CG GLUA7124.844 36.967 6.8441.00 54.12C
ATOM562CD GLUA7123.544 36.406 7.4341.00 56.63C
ATOM563OEl GLUA7123.593 35.9628.5941.00 57.98O
ATOM564OE2GLUA7122.487 36.3866.7611.00 58.07O
ATOM565C GLUA7124.200 40.1595.1161.00 51.22C
ATOM566O GLUA7124.656 40.9005.9961.0050.96O
ATOM567N GLUA7224.181 40.4773.8191.0051.67N
ATOM568CA GLUA7224.535 41.814 3.3171.00 52.18C
ATOM569CB GLUA7224.599 41.831 1.7921.00 52.03C
ATOM570CG GLUA7225.965 41.556 1.1971.00 50.33C
ATOM571CD GLUA7225.940 41.577-0.3051.0047.85C
[0254]ATOM572OEl GLUA 7224.82741.605-0.8731.0047.52OATOM573OE2GLUA 7227.03141.559-0.9231.00 47.12O
ATOM574C GLUA 7223.54242.8853.7461.0052.67C
ATOM575O GLUA 7223.79944.0603.5521.00 53.12O
ATOM576N GLYA 7322.39942.4744.2871.00 53.08N
ATOM577CA GLYA 7321.37143.4074.7341.00 53.79C
ATOM578C GLYA 7321.41743.6136.2371.00 54.31C
ATOM579O GLYA 7320.84744.5726.7601.00 54.66O·ATOM580N ARGA 7422.08842.7026.9341.00 54.25N
ATOM581CA ARGA 7422.280 42.8288.3691.00 54.51C
ATOM582CB ARGA 7422.09441.4699.0321.00 54.52C
ATOM583CG ARGA 7420.680 40.9638.8971.00 56.24C
ATOM584CD ARGA 7420.567 39.5069.2671.00 58.96C
ATOM585NE ARGA 7419.21939.0019.0281.00 60.96N
ATOM586CZ ARGA 7418.85437.7339.2041.0062.86C
ATOM587NHl ARGA 7419.73836.8279.6171.00 62.48N
ATOM588NH2ARGA 7417.59937.3668.9591.0064.12N
ATOM589C ARGA 7423.63543.4538.7311.00 54.15C
ATOM590O ARGA 7423.90743.7419.9021.00 54.39O
ATOM591N GLYA 7524.47043.6737.7201.00 53.79N
ATOM592CA GLYA 7525.81244.2047.9201.00 52.82C
ATOM593C GLYA 7526.84143.1828.3851.00 52.44C
ATOM594O GLYA 7527.91443.5608.8981.00 52.47O
ATOM595N ASNA 7626.53441.8958.2031.0051.25N
ATOM596CA ASNA 7627.43340.8168.6401.0049.98C
ATOM597CB ASNA 7626.64639.5278.8841.00 50.09C
ATOM598CG ASNA 7625.50339.7149.8631.00 50.50C
ATOM599ODl ASNA 7625.37240.76910.4761.0051.85O
ATOM600ND2ASNA 7624.67438.68110.0241.00 50.25N
ATOM601C ASNA 7628.58440.5757.6691.0048.78C
ATOM602O ASNA 7628.58139.6186.9191.00 48.63O
ATOM603N GLUA 7729.58841.4397.7021.0047.72N
ATOM604CA GLUA 7730.63041.4436.6611.0046.85C
ATOM605CB GLUA 7731.42142.7806.6771.0047.24C
ATOM606CG GLUA 7731.07643.7955.5171.0047.78C
ATOM607CD GLUA 7729.64143.6854.9661.00 50.88C
ATOM608OEl GLUA 7729.46343.1243.8611.00 51.12O
ATOM609OE2GLUA 7728.68344.1545.6281.00 52.81O
ATOM610C GLUA 7731.54940.2076.6581.00 45.97C
ATOM611O GLUA 7732.01039.7575.5891.0045.43O
ATOM612N GLUA 7831.79539.6737.8541.00 44.56N
ATOM613CA GLUA 7832.53538.4258.0681.0043.59C
ATOM614CB GLUA 7832.67038.1499.5851.00 44.53C
ATOM615CG GLUA 7831.72738.98610.5431.00 47.94C
[0255]ATOM 616CD GLUA 78 30.230 38.577 10.515 1.0050.60 CATOM 617OEl GLUA 78 29.619 38.5589.440 1.00 50.79O
ATOM 618OE2GLUA 78 29.644 38.29911.584 1.00 53.75O
ATOM 619C GLUA 78 31.901 37.2047.355 1.00 42.06C
ATOM 620O GLUA 78 32.604 36.4286.685 1.0041.33O
ATOM 621N HISA 79 30.588 37.0417.526 1.0039.62N
ATOM622CA HISA 79 29.820 35.9926.860 1.00 38.65C
ATOM623CB HISA 79 28.395 35.9297.409 1.00 38.35C
ATOM624CG HISA 79 28.324 35.3308.776 1.00 38.61C
ATOM625NDl HISA 79 27.308 35.6119.664 1.0040.14N
ATOM626CEl HISA 79 27.526 34.958 10.794 1.00 39.85C
ATOM 627NE2HISA 79 28.658 34.28210.678 1.0038.96N
ATOM 628CD2HISA 79 29.183 34.5079.430 1.0039.04C
ATOM629C HISA 79 29.801 36.1935.367 1.00 38.14C
ATOM630O HISA 79 30.186 35.2994.638 1.0038.83O
ATOM631N VALA 80 29.395 37.3844.922 1.00 37.55N
ATOM632CA VALA 80 29.389 37.7533.508 1.00 36.69C
ATOM633CB VALA 80 29.121 39.2703.327 1.00 37.21C
ATOM634CGl VALA 80 29.349 39.7071.876 1.0036.34C
ATOM635CG2VALA 80 27.718 39.6063.793 1.00 36.33C
ATOM636C VALA 80 30.643 37.3182.741 1.00 36.54C
ATOM637O VALA 80 30.529 36.7291.661 1.0036.63O
ATOM638N THRA 81 31.832 37.6003.271 1.0035.02N
ATOM639CA THRA 81 33.040 37.1932.571 1.00 35.45C
ATOM640CB THRA 81 34.338 37.8883.098 1.00 35.74C
ATOM641OGl THRA 81 35.390 36.9203.212 1.00 37.93O
ATOM642CG2THRA 81 34.108 38.5454.434 1.00 34.35C
ATOM643C THRA 81 33.191 35.6702.409 1.00 35.94C
ATOM644O THRA 81 33.532 35.1781.315 1.00 36.29O
ATOM645N LEUA 82 32.905 34.9203.480 1.00 35.89N
ATOM646CA LEUA 82 32.815 33.4563.398 1.00 34.90C
ATOM647CB LEUA 82 32.471 32.8534.765 1.00 34.62C
ATOM648CG LEUA 82 33.513 32.3805.801 1.00 33.52C
ATOM649CDl LEUA 82 33.365 33.1277.126 1.0031.11C
ATOM650CD2LEUA 82 34.968 32.3065.282 1.0030.15C
ATOM651C LEUA 82 31.745 33.0072.376 1.0035.17C
ATOM652O LEUA 82 32.038 32.2101.491 1.00 34.94O
ATOM653N ILEA 83 30.517 33.5062.525 1.00 34.70N
ATOM654CA ILEA 83 29.442 33.1991.602 1.00 34.98C
ATOM655CB ILEA 83 28.139 33.9311.973 1.0034.86C
ATOM656CGl ILEA 83 27.697 33.5683.386 1.00 34.20C
ATOM657CDl ILEA 83 26.841 34.6334.050 1.00 32.92C
ATOM658CG2ILEA 83 26.993 33.5081.020 1.00 34.47C
ATOM659C ILEA 83 29.777 33.4350.106 1.00 35.49C
[0256]ATOM660O ILEA 8329.448 32.587-0.7441.0036.28OATOM 661N LYSA 8430.398 34.570-0.2141.00 35.28N
ATOM 662CA LYSA 8430.765 34.940-1.5971.00 35.63C
ATOM 663CB LYSA 8431.392 36.334-1.6531.00 36.13C
ATOM 664CG LYSA 8430.446 37.486-1.6711.0036.32C
ATOM 665CD LYSA 8431.182 38.734-2.1601.00 38.88C
ATOM666CE LYSA 8430.221 39.880-2.4471.00 39.43C
ATOM667NZ LYSA 8429.144 39.940-1.4321.0040.61N
ATOM668C LYSA 8431.774 33.984-2.2141.00 35.79C
ATOM669O LYSA 8431.681 33.629-3.3911.00 35.96O
ATOM670N GLUA 8532.741 33.577-1.4051.00 35.51N
ATOM671CA GLUA 85 33.774 32.672-1.8511.0035.66C
ATOM672CB GLUA 8534.857 32.525-0.7701.0035.16C
ATOM673CG GLUA 8536.073 31.731-1.2671.0037.48C
ATOM674CD GLUA 8537.039 31.271-0.1651.0038.00C
ATOM675OEl GLUA 8536.889 31.6931.0101.0042.51O
ATOM676OE2GLUA 8537.952 30.473-0.4861.00 38.75O
ATOM677C GLUA 8533.172 31.314-2.1901.00 34.88C
ATOM678O GLUA 8533.615 30.651-3.1261.00 35.52O
ATOM679N TYRA 8632.189 30.903-1.3911.00 33.93N
ATOM680CA TYRA 8631.469 29.645-1.5581.00 32.84C
ATOM681CB TYRA 8630.597 29.391-0.3111.00 32.39C
ATOM682CG TYRA 8630.046 27.975-0.2321.00 32.14C
ATOM683CDl TYRA 8630.902 26.889-0.0671.00 30.29C
ATOM684CEl TYRA 8630.406 25.591-0.0051.00 31.46C
ATOM685CZ TYRA 8629.026 25.374-0.1071.0031.03C
ATOM686OH TYRA 8628.545 24.101-0.0401.0030.33O
ATOM687CE2 TYRA 8628.157 26.428-0.2561.00 29.62C
ATOM688CD2TYRA 8628.670 27.731-0.3131.00 30.70C
ATOM689C TYRA 8630.620 29.683-2.8601.0032.19C
ATOM690O TYRA 8630.721 28.812-3.6971.0031.88O
ATOM691N ARGA 8729.842 30.741-3.0401.0031.85N
ATOM692CA ARGA 87 29.170 30.997-4.3021.0032.68C
ATOM693CB ARGA 8728.414 32.335-4.2271.0032.88C
ATOM694CG ARGA 87 27.662 32.701-5.4901.00 34.71C
ATOM695CD ARGA 87 26.773 33.872-5.2411.0037.74C
ATOM696NE ARGA 8727.515 35.080-4.8891.0039.96N
ATOM697CZ ARGA 8727.795 36.066-5.7391.0042.53C
ATOM698NHl ARGA 8727.401 35.988-7.0111.00 42.21N
ATOM699NH2ARGA 8728.457 37.138-5.3141.0041.79N
ATOM700C ARGA 8730.127 30.980-5.5041.0032.79C
ATOM701O ARGA 8729.812 30.415-6.5651.0033.08O
ATOM702N GLYA 8831.297 31.587-5.3431.00 32.71N
ATOM703CA GLYA 8832.300 31.583-6.3951.00 32.61C
[0257]ATOM704C GLYA 8832.659 30.202 -6.8641.00 32.86CATOM705O GLYA 8832.816 29.952 -8.0711.0033.18O
ATOM706N LYSA 8932.804 29.307 -5.8901.00 32.85N
ATOM707CA LYSA 8933.039 27.883 -6.1221.0032.31C
ATOM708CB LYSA 8933.286 27.230 -4.7791.00 31.96C
ATOM709CG LYSA 8933.799 25.833 -4.8311.0034.24C
ATOM710CD LYSA 8933.758 25.226 -3.4201.00 35.32C
ATOM711CE LYSA 8934.808 24.148 -3.2301.00 33.95C
ATOM712NZ LYSA 8934.799 23.761 -1.8081.0032.66N
ATOM713C LYSA 8931.857 27.198 -6.8451.0031.95C
ATOM714O LYSA 8932.080 26.357 -7.7231.00 32.57O
ATOM715N ILRA 9030.614 27.527 -6.4641.00 30.85N
ATOM716CA ILEA 9029.420 26.969 -7.1671.0029.67C
ATOM717CB ILEA 9028.093 27.213 -6.4031.0029.59C
ATOM718CGl ILEA 9028.118 26.480 -5.0531.0027.79C
ATOM719CDl ILEA 9026.983 26.877 -4.1051.0027.44C
ATOM720CG2ILEA 9026.874 26.697 -7.1971.0027.48C
ATOM721C ILEA 9029.344 27.504 -8.6021.00 30.24C
ATOM722O ILEA 9029.099 26.737 -9.5061.0031.09O
ATOM723N GLUA 9129.580 28.805 -8.7961.00 30.77N
ATOM724CA GLUA 91 29.619 29.450-10.1271.00 30.70C
ATOM725CB GLUA 9129.763 30.964 -9.9961.0031.06C
ATOM726CG GLUA 91 28.561 31.664 -9.3811.0029.69C
ATOM727CD GLUA 9128.765 33.151 -9.2591.00 29.43C
ATOM728OEl GLUA 9129.726 33.689 -9.8431.00 34.98O
ATOM729OE2GLUA 9127.951 33.822 -8.6171.00 27.73O
ATOM730C GLUA 9130.738 28.915-11.0171.0031.40C
ATOM731O GLUA 9130.567 28.741 -12.2421.00 30.37O
ATOM732N ALAA 9231.881 28.618-10.3991.0031.63N
ATOM733CA ALAA 92 32.953 27.925-11.1111.00 31.64C
ATOM734CB ALAA 9234.194 27.695-10.1941.0031.85C
ATOM735C ALAA 9232.420 26.614-11.6921.0031.79C
ATOM736O ALAA 9232.744 26.239-12.8171.0032.98O
ATOM737N GLUA 9331.573 25.936-10.9411.00 30.63N
ATOM738CA GLUA 93 31.067 24.657-11.3691.00 30.67C
ATOM739CB GLUA 9330.467 23.875-10.1941.00 30.59C
ATOM740CG GLUA 93 31.440 22.940 -9.5361.00 32.40C
ATOM741CD GLUA 93 30.798 22.198 -8.3931.0037.60C
ATOM742OEl GLUA 9331.525 21.740 -7.4811.00 39.18O
ATOM743OE2GLUA 9329.551 22.074 -8.4041.00 37.67O
ATOM744C GLUA 9330.029 24.803 -12.4631.0029.12C
ATOM745O GLUA 9330.045 24.048-13.4071.0028.16O
ATOM746N LEUA 9429.152 25.776-12.2871.0028.54N
ATOM747CA LEUA 94 28.128 26.177-13.2561.00 29.37C
[0258]ATOM748CB LEUA 94 27.411 27.418-12.725 1.0028.55CATOM749CG LEUA 94 26.090 27.491 -11.935 1.00 29.94 C
ATOM750CDl LEUA 94 26.239 28.451 -10.703 1.00 29.49C
ATOM751CD2LEUA 94 25.613 26.178-11.502 1.00 26.53C
ATOM752C LEUA 94 28.752 26.498-14.622 1.00 29.05C
ATOM753O LEUA 94 28.275 26.013-15.656 1.00 27.18O
ATOM754N SERA 95 29.802 27.326-14.600 1.0028.80N
ATOM755CA SERA 95 30.513 27.770-15.793 1.0029.91C·ATOM756CB SERA 95 31.593 28.819-15.456 1.00 30.00C
ATOM757OG SERA 95 31.075 29.972-14.816 1.00 30.31O
ATOM758C SERA 95 31.175 26.606-16.511 1.00 30.79C
ATOM759O SERA 95 31.282 26.618-17.728 1.00 32.51O
ATOM760N LYSA 96 31.635 25.610-15.763 1.0031.10N
ATOM761CA LYSA 96 32.261 24.440-16.345 1.0031.38C
ATOM762CB LYSA 96 33.133 23.723-15.312 1.00 32.09C
ATOM763CG LYSA 96 34.639 24.104-15.365 1.00 36.48C
ATOM764CD LYSA 96 34.900 25.643-15.399 1.0038.14C
ATOM765CE LYSA 96 35.058 26.245-14.015 1.00 38.67C
ATOM766NZ LYSA 96 34.849 27.712-14.076 1.00 39.45N
ATOM767C LYSA 96 31.245 23.459-16.912 1.0031.01C
ATOM768O LYSA 96 31.518 22.825-17.919 1.00 30.46O
ATOM769N ILEA 97 30.103 23.300-16.245 1.00 30.35N
ATOM770CA ILEA 97 29.051 22.383-16.727 1.00 30.28C
ATOM771CB ILEA 97 27.939 22.128-15.655 1.0029.81C
ATOM772CGl ILEA 97 28.561 21.636-14.341 1.0029.24C
ATOM773CDl ILEA 97 27.798 22.031 -13.107 1.0028.59C
ATOM774CG2ILEA 97 26.857 21.121 -16.152 1.0029.49C
ATOM775C ILEA 97 28.498 22.924-18.063 1.00 30.09C
ATOM776O ILEA 97 28.515 22.214-19.057 1.0031.71O
ATOM777N CYSA 98 28.058 24.178-18.075 1.00 29.43N
ATOM778CA CYSA 98 27.586 24.872-19.284 1.0029.48C
ATOM779CB CYSA 98 27.253 26.340-18.984 1.0027.53C
ATOM780SG CYSA 98 25.853 26.765 -17.881 1.0025.39S
ATOM781C CYSA 98 28.594 24.787 -20.452 1.00 30.46C
ATOM782O CYSA 98 28.240 24.401-21.558 1.0031.62O
ATOM783N ASPA 99 29.857 25.126 -20.188 1.0031.36N
ATOM784CA ASPA 99 30.922 25.085 -21.186 1.00 32.17C
ATOM785CB ASPA 99 32.271 25.549-20.560 1.00 33.03C
ATOM786CG ASPA 99 33.447 25.406-21.523 1.00 35.55C
ATOM787ODl ASPA 99 33.787 26.402-22.181 1.0043.23O
ATOM788OD2ASPA 99 34.025 24.309-21.652 1.00 37.25O
ATOM789C ASPA 99 31.077 23.712-21.815 1.0031.89C
ATOM790O ASPA 99 31.269 23.595 -23.027 1.0032.70O
ATOM791N GLYA100 31.025 22.673 -20.983 1.0031.59N
[0259]ATOM792CA GLYA100 31.018 21.294-21.464 1.0031.05CATOM793C GLYA10029.98921.056-22.5821.00 30.47C
ATOM794O GLYA10030.34620.611 -23.6651.00 30.74O
ATOM795N ILEA 10128.71821.361 -22.3161.00 30.07N
ATOM796CA ILEA 10127.60621.052 -23.2561.0028.15C
ATOM797CB ILEA 10126.23820.900-22.5121.0027.85C
ATOM798CGl ILEA 10125.05020.599 -23.4711.0026.33C
ATOM799CDl ILEA 10125.25019.370 -24.3211.00 20.64C·
ATOM800CG2 ILEA 10125.92322.107-21.6691.00 26.52C
ATOM801C ILEA 10127.58022.096 -24.3801.0028.52C
ATOM802O ILEA 10127.34821.758-25.5341.00 27.98O
ATOM803N LEU A10227.86023.356 -24.0461.0029.39N
ATOM804CA LEUA102 27.955 24.410-25.0741.0029.94C
ATOM805CB LEU A102 28.17525.798 -24.4501.0028.61C
ATOM806CG LEU A102 27.062 26.863 -24.3481.0028.20C
ATOM807CDl LEU A10225.61526.371 -24.6411.0022.08C
ATOM808CD2 LEU A10227.15027.587 -23.0381.0023.16C
ATOM809C LEUA10229.04524.079 -26.1141.00 30.92C
ATOM810O LEUA10228.88924.422 -27.2831.0029.96O
ATOM811N LYSA10330.14023.406 -25.7031.00 32.42N
ATOM812CA LYS A10331.17823.005 -26.6871.00 33.53C
ATOM813CB LYSA10332.52322.711 -26.0311.00 34.14C
ATOM814CG LYS A10333.29223.986 -25.7491.00 36.26C
ATOM815CD LYS A10334.69023.736-25.1891.0041.22C
ATOM816CE LYS A10335.60924.895 -25.5571.00 42.52C
ATOM817NZ LYSA10335.07026.241 -25.1541.00 43.02N
ATOM818C LYSA10330.75521.863 -27.5811.00 33.62C
ATOM819O LYSA10331.10321.825 -28.7571.00 34.68O
ATOM820N LEU A10429.99020.940 -27.0191.00 32.79N
ATOM821CA LEU A104 29.500 19.788-27.7411.00 32.39C
ATOM822CB LEU A10429.06618.735-26.7161.00 32.42C
ATOM823CG LEU A104 28.759 17.320 -27.1611.0031.16C
ATOM824CDl LEUA10429.97716.631 -27.7691.0029.66C
ATOM825CD2 LEUA10428.21516.560 -25.9801.00 29.94C
ATOM826C LEUA10428.35420.120-28.7191.0031.97C
ATOM827O LEUA10428.25119.535-29.8021.00 31.22O
ATOM828N LEUA10527.49821.044-28.3021.00 31.40N
ATOM829CA LEUA105 26.47521.625 -29.1551.00 30.97C
ATOM830CB LEUA10525.60022.621 -28.3641.00 30.60C
ATOM831CG LEUA105 24.616 22.046 -27.3291.00 29.50C
ATOM832CDl LEUA10523.32021.507-27.9721.00 27.29C
ATOM833CD2 LEUA10524.30523.058-26.1921.0028.38C
ATOM834C LEUA10527.10422.279-30.4011.00 32.03C
ATOM835O LEUA10526.66922.031-31.5311.00 30.28O
[0260]ATOM836N ASPA106 28.12023.112-30.1661.00 32.69NATOM837CA ASPA106 28.83223.840-31.2261.00 34.53C
ATOM838CB ASPA106 29.73924.930 -30.6321.00 34.82C
ATOM839CG ASPA106 28.97226.138 -30.1971.00 39.24C
ATOM840ODl ASPA106 27.78926.286 -30.6141.0041.30O
ATOM841OD2ASPA106 29.55026.946 -29.4221.0044.10O
ATOM842C ASPA106 29.66922.990 -32.1821.00 34.19C
ATOM843O ASPA106 29.79223.339-33.3541.00 34.33O
ATOM844N SERA 107 30.25521.901 -31.6811.00 34.32N
ATOM845CA SERA 107 31.13521.068 -32.4961.0034.06C
ATOM846CB SERA 107 32.33820.612-31.6811.0033.79C
ATOM847OG SERA 107 31.959 19.734 -30.6351.00 36.73O
ATOM848C SERA 107 30.45719.875 -33.1651.00 33.10C
ATOM849O SERA 107 30.83019.484 -34.2601.00 32.78O
ATOM850N HISA108 29.46419.301 -32.5101.00 32.75N
ATOM851CA HISA108 28.85018.074-32.9911.00 31.83C
ATOM852CB HISA108 29.08216.922 -31.9881.0031.81C·
ATOM853CG HISA108 30.48816.402-31.9841.00 33.66C
ATOM854NDl HISA108 31.53017.079-31.3811.00 33.18N
ATOM855CEl HISA108 32.65416.409 -31.5741.0031.49C
ATOM856NE2HISA108 32.38015.322-32.2671.00 33.24N
ATOM857CD2HISA108 31.03315.294-32.5431.00 32.74C
ATOM858C HlSA 108 27.37418.247 -33.1871.0032.02C
ATOM859O HIS A108 26.83017.940 -34.2741.00 30.92O
ATOM860N LEU A109 26.71418.697 -32.1121.0031.75N
ATOM861CA LEUA109 25.262 18.559-32.0151.0031.65C
ATOM862CB LEUA109 24.80218.656 -30.5481.00 30.95C
ATOM863CG LEU A109 25.414 17.574 -29.6311.0030.12C
ATOM864CDl LEUA109 24.86117.642-28.2371.00 25.70C
ATOM865CD2LEUA109 25.28716.133-30.2151.0026.65C
ATOM866C LEUA109 24.45319.461 -32.9531.00 31.93C
ATOM867O LEUA109 23.60818.963 -33.7681.00 32.07O
ATOM868N VALA HO 24.67020.767 -32.8391.0031.47N
ATOM869CA VALA HO 23.97321.712-33.7291.00 32.21C
ATOM870CB VALA110 24.09623.200 -33.2911.00 32.24C
ATOM871CGl VALA110 23.43524.130 -34.3111.0031.63C
ATOM872CG2VALA110 23.49723.422 -31.8891.0029.82C
ATOM873C VALAHO 24.42721.491 -35.1891.0032.97C
ATOM874O VALA110 23.58221.282 -36.0451.0033.49O
ATOM875N PROA 111 25.75821.504-35.4581.00 33.65N
ATOM876CA PROA 111 26.22721.303 -36.8251.00 34.21C
ATOM877CB PROA 111 27.75421.307-36.6651.00 34.18C
ATOM878CG PROA 111 27.95322.236-35.4791.00 33.71C
ATOM879CD PROA 111 26.90021.797-34.5531.00^14C
[0261]ATOM880C PROA 11125.76320.028 -37.4881.00 34.75CATOM881O PROA 11125.60820.035 -38.7031.00 35.69O
ATOM882N SERA 11225.53818.968 -36.7021.00 34.66N
ATOM883CA SERA 11225.14517.644-37.1881.00 33.96C
ATOM884CB SERA 11225.53316.577 -36.1461.00 34.66C
ATOM885OG SERA 11224.46716.210-35.2511.0034.24O
ATOM886C SERA 11223.66717.464-37.5431.00 33.87C
ATOM887O SERA 11223.30616.482 -38.1761.00 34.25O
ATOM888N SERA 11322.81918.386-37.0851.00 33.30N
ATOM889CA SERA 11321.38718.260 -37.1781.00 32.48C
ATOM890CB SERA 11320.72619.236-36.2131.0031.77C
ATOM891OG SERA 11320.87218.739-34.9121.0031.71O
ATOM892C SERA 11320.87418.478 -38.5981.00 32.08C
ATOM893O SERA 11321.09119.524-39.1821.0031.69O
ATOM894N THRA11420.19817.479 -39.1501.0031.93N
ATOM895CA THRA11419.70917.600-40.5381.0031.87 C
ATOM896CB THR A11419.90716.294-41.3801.0031.88C
ATOM897OGl THRA11419.33215.169 -40.7011.00 32.60O
ATOM898CG2THRA11421.39016.009 -41.6601.00 32.46C
ATOM899C THRA11418.25218.031-40.5561.0031.50C
ATOM900O THRA11417.82018.752 -41.4441.00 30.80O
ATOM901N ALAA11517.52217.596 -39.5341.0031.86N
ATOM902CA ALAA11516.07817.721 -39.4741.00 32.13C
ATOM903CB ALAA11515.46816.413 -38.9641.00 32.63C
ATOM904C ALAA11515.66718.868 -38.5821.00 32.38C
ATOM905O ALAA11516.45619.320 -37.7131.00 32.37O
ATOM906N ALAA11614.43019.332 -38.7881.0031.56N
ATOM907CA ALAA11613.88620.460 -38.0261.0031.20C
ATOM908CB ALAA11612.60920.953 -38.6241.00 30.42C
ATOM909C ALAA11613.73320.252 -36.5081.0031.19C
ATOM910O ALAA11614.16221.107 -35.7451.0031.63O
ATOM911N GLUA11713.13519.144-36.0661.0031.39N
ATOM912CA GLUA11712.891 18.933-34.6121.00 32.95C
ATOM913CB GLUA11712.17217.596 -34.3291.00 32.05C
ATOM914CG GLUA11711.02917.226 -35.3021.00 36.80C
ATOM915CD GLUA11710.487 15.801 -35.1211.00 37.21C
ATOM916OEl GLUA11711.25014.948 -34.5941.0043.55O
ATOM917OE2 GLUA1179.31315.533 -35.5271.00 39.31O
ATOM918C GLUA11714.23718.919-33.8691.0031.81C
ATOM919O GLU A11714.32519.174-32.6701.0031.64O
ATOM920N SERA 11815.25618.569-34.6311.00 30.99N
ATOM921CA SERA 11816.53518.183 -34.1501.00 31.60C
ATOM922CB SERA 11817.05117.123 -35.1381.00 32.05C
ATOM923OG SERA 11818.45017.031-35.1901.00 34.83O
[0262]ATOM924C SERA 11817.393 19.460 -34.0251.00 30.81CATOM925O SERA 11818.060 19.697 -33.0221.00 32.09O
ATOM926N LYSA11917.284 20.314-35.0301.0030.00N
ATOM927CA LYSA11917.815 21.653-35.0501.0029.55C
ATOM928CB LYSA11917.471 22.219-36.4301.00 30.50C
ATOM929CG LYSA11918.442 23.164-37.0581.00 28.35C
ATOM930CD LYS A11919.697 22.499-37.5551.0027.00C
ATOM931CE LYSA11920.850 23.527-37.3511.00 28.10C·
ATOM932NZ LYSA11922.155 23.076 -37.9701.0029.11N
ATOM933C LYSA11917.206 22.554-33.9581.0028.67C
ATOM934O LYSA11917.918 23.290 -33.2811.0028.92O
ATOM935N VALA12015.883 22.520 -33.8201.00 27.24N
ATOM936CA VALA12015.180 23.258 -32.7401.0025.87C
ATOM937CB VALA12013.630 23.148 -32.8881.0024.73C
ATOM938CGl VALA12012.874 23.963 -31.8391.00 23.99C
ATOM939CG2VALA12013.248 23.605 -34.2211.00 24.72C
ATOM940C VALA12015.597 22.820 -31.3351.0025.18C
ATOM941O VALA12015.706 23.657 -30.4401.00 24.66O
ATOM942N PHEA12115.787 21.509 -31.1551.00 25.47N
ATOM943CA PHEA12116.134 20.901 -29.8661.0025.33C
ATOM944CB PHEA12116.167 19.371 -30.0221.00 25.73C
ATOM945CG PHEA12116.223 18.598-28.7061.0026.22C
ATOM946CDl PHEA12117.464 18.270 -28.1161.00 25.22C
ATOM947CEl PHEA12117.517 17.552 -26.9061.0026.34C
ATOM948CZ PHEA ] 2116.320 17.137 -26.2881.0024.95C
ATOM949CE2 PHEA12115.084 17.462-26.8631.0026.50C
ATOM950CD2 PHEA12115.038 18.181 -28.0721.0025.26C
ATOM951C PHEA12117.487 21.406 -29.3641.0025.73C
ATOM952O PHEA12117.650 21.773 -28.1861.0026.09O
ATOM953N TYRA12218.453 21.422 -30.2691.00 25.59N
ATOM954CA TYRA12219.837 21.693 -29.9081.0025.58C
ATOM955CB TYRA12220.818 20.996 -30.8481.0024.91C
ATOM956CG TYRA12220.813 19.506-30.6351.0025.93C
ATOM957CDl TYRA12221.152 18.940 -29.3881.00 24.16C
ATOM958CEl TYRA12221.126 17.564-29.1981.00 24.70C
ATOM959CZ TYRA12220.783 16.736-30.2781.0026.70C
ATOM960OH TYRA12220.764 15.342 -30.1831.00 25.90O
ATOM961CE2 TYRA12220.459 17.293 -31.4991.00 25.96C
ATOM962CD2 TYRA12220.449 18.653 -31.6691.00 26.15C
ATOM963C TYRA12220.131 23.137-29.8221.00 25.17C
ATOM964O TYRA12220.921 23.513-28.9911.00 26.92O
ATOM965N LEUA12319.485 23.951 -30.6561.00 25.00N
ATOM966CA LEUA12319.512 25.424-30.4931.0023.31C
ATOM967CB LEUA12318.978 26.141 -31.7381.0024.38C
[0263]ATOM968CG LEUA123 19.73125.937 -33.058 1.0026.24CATOM969 CDl LEU A123 18.85826.301 -34.305 1.0024.04C
ATOM970 CD2 LEUA123 21.05126.713 -32.997 1.0024.75C
ATOM971C LEUA123 18.73125.856 -29.263 1.00 22.63C
ATOM972O LEUA123 19.18526.745 -28.513 1.0020.48O
ATOM973N LYS A124 17.56425.246 -29.019 1.0021.22N
ATOM974 CA LYS A124 16.91325.482-27.711 1.0021.95C ATOM975CB LYSA124 15.60724.717-27.555 1.0021.75C
ATOM976CG LYS A124 14.98624.799 -26.166 1.0021.76C
ATOM977CD LYS Λ124 13.92623.689 -26.053 1.0023.29C
ATOM978CE LYS A124 13.72623.243 -24.587 1.0023.70C
ATOM979NZ LYS A124 14.91522.550-24.019 1.0023.39N
ATOM980C LYS A124 17.84925.097 -26.550 1.00 22.49C
ATOM981O LYS A124 17.92325.784-25.551 1.0022.62O
ATOM982N META 125 18.53523.973 -26.703 1.0023.76N
ATOM983CA META 125 19.42923.469 -25.688 1.0025.46C
ATOM984CB META 125 19.93122.094-26.109 1.0025.30C
ATOM985CG META 125 19.60320.997 -25.139 1.0026.28C
ATOM986SD META 125 20.56819.504-25.400 1.00 29.28S
ATOM987CE META 125 21.83719.667 -24.137 1.0028.84C
ATOM988C META 125 20.59624.453 -25.497 1.0024.34C
ATOM989O META 125 21.02224.676 -24.383 1.00 25.73O
ATOM990N LYSA126 21.07025.070 -26.580 1.00 24.81N
ATOM991CA LYS A126 22.17526.083 -26.518 1.0024.86C
ATOM992CB LYSA126 22.73926.294 -27.926 1.00 25.73C
ATOM993CG LYS A126 23.73227.422-28.124 1.0024.47C
ATOM994CD LYS A126 24.24027.344 -29.540 1.00 27.15C
ATOM995CE LYSA126 24.63528.681 -30.082 1.0029.64C
ATOM996NZ LYSA126 26.08428.981 -29.882 1.00 35.87N
ATOM997C LYSA126 21.72127.396 -25.881 1.0024.00C
ATOM998O LYS A126 22.42727.985 -25.042 1.00 23.21O
ATOM999N GLYA127 20.53227.849-26.273 1.0022.42N
ATOM1000CA GLYA127 19.77728.859-25.525 1.0022.11C
ATOM1001C GLYA127 19.62128.617 -24.021 1.0021.93C
ATOM1002O GLYA127 19.83829.533 -23.230 1.00 24.30O
ATOM1003N ASPA128 19.28327.397 -23.608 1.0020.97N
ATOM1004CA ASPA128 19.14527.020-22.163 1.0019.25C
ATOM1005CB ASPA128 18.71625.562-22.027 1.00 17.53C
ATOM1006CG ASPA128 17.30225.285 -22.595 1.0017.82C
ATOM1007ODl ASPA128 16.49726.227 -22.710 1.0021.16O
ATOM1008OD2 ASPA128 16.94824.118-22.897 1.0020.45O
ATOM1009C ASPA128 20.45927.277-21.362 1.0019.98C
ATOM1010O ASPA128 20.44327.918-20.347 1.0018.95O
ATOM1011N TYRA129 21.57826.796 -21.874 1.00 20.67N
[0264]ATOM1012CA TYRA129 22.838 26.819-21.169 1.00 21.44CATOM1013CB TYRA129 23.756 25.654-21.681 1.0020.98C
ATOM1014CG TYRA129 23.209 24.379-21.142 1.0019.20C
ATOM1015CDl TYRA129 22.237 23.637 -21.861 1.00 19.66C
ATOM1016CEl TYRA129 21.648 22.519-21.293 1.0012.32C
ATOM1017CZ TYRA129 21.993 22.144 -20.021 1.0019.68C
ATOM1018OH TYRA129 21.436 21.025-19.480 1.0021.02O
ATOM1019CE2 TYRA129 22.943 22.842-19.290 1.00 14.53C ATOM1020CD2TYRA129 23.498 23.984-19.837 1.0017.83C
ATOM1021C TYRA129 23.477 28.204-21.132 1.00 23.26C
ATOM1022O TYRA129 24.150 28.571 -20.175 1.00 24.52O
ATOM1023N HISA130 23.264 28.995 -22.178 1.0024.23N
ATOM1024CA HISA130 23.538 30.422 -22.084 1.00 24.89C
ATOM1025CB HISA130 23.414 31.094-23.438 1.00 25.01C
ATOM1026CG HISA130 24.578 30.832 -24.329 1.00 26.33C
ATOM1027NDl HISA130 25.866 31.213-23.992 1.0028.44N
ATOM1028CEl HISA130 26.689 30.852 -24.961 1.00 27.52C
ATOM1029NE2 HISA130 25.981 30.277 -25.919 1.00 29.76N
ATOM1030CD2 HISA130 24.660 30.237 -25.541 1.0026.95C
ATOM1031C HISA130 22.651 31.129 -21.093 1.00 25.27C
ATOM1032O HISA130 23.101 32.036 -20.350 1.0026.08O
ATOM1033N ARGA131 21.385 30.751 -21.080 1.00 24.46N
ATOM1034CA ARGA131 20.459 31.311 -20.103 1.00 23.83C
ATOM1035CB ARGA131 19.003 30.882 -20.403 1.00 22.95C
ATOM1036CG ARGA131 18.075 31.098-19.261 1.00 20.50C
ATOM1037CD ARGA131 16.595 30.984-19.675 1.00 23.27C
ATOM1038NE ARGA131 16.201 29.646 -20.155 1.0015.96N
ATOM1039CZ ARGA131 15.832 28.613-19.391 1.0019.68C
ATOM1040NHl ARGA131 15.816 28.750-18.053 1.0016.20N
ATOM1041NH2ARGA131 15.429 27.433 -19.988 1.0017.95N
ATOM1042C ARGA131 20.830 30.944-18.661 1.0023.69C
ATOM1043O ARGA131 20.608 31.766-17.779 1.0024.36O
ATOM1044N TYRA132 21.341 29.721 -18.416 1.00 23.48N
ATOM1045CA TYRA132 21.843 29.371 -17.072 1.00 24.16C
ATOM1046CB TYRA132 22.052 27.854-16.843 1.00 22.77C
ATOM1047CG TYRA132 20.898 26.960-17.263 1.00 20.31C
ATOM1048CDl TYRA132 21.122 25.707-17.802 1.0017.23C
ATOM1049CEl TYRA132 20.028 24.885-18.243 1.0021.19C
ATOM1050CZ TYRA132 18.732 25.331-18.129 1.0017.26C
ATOM1051OH TYRA132 17.640 24.556-18.524 1.00 23.94O
ATOM1052CE2 TYRA132 18.498 26.567-17.604 1.0017.45C
ATOM1053CD2 TYRA132 19.583 27.387-17.165 1.00 20.41C
ATOM1054C TYRA132 23.112 30.161 -16.736 1.0024.68C
ATOM1055O TYRA132 23.403 30.391 -15.570 1.00 26.18O
[0265]ATOM1056N LEUA133 23.86430.598 -17.742 1.0025.85NATOM1057CA LEUA133 25.06331.424-17.472 1.0027.37 C
ATOM1058CB LEUA133 26.02631.483-18.676 1.0026.85 C
ATOM1059CG LEUA133 26.907 30.274-19.004 1.0025.07 C
ATOM1060CDl LEUA133 27.68430.463 -20.295 1.00 20.35C
ATOM1061CD2 LEUA133 27.88329.988-17.886 1.0027.13C
ATOM1062C LEUA133 24.61432.817-17.103 1.00 28.86C
ATOM1063O LEUA133 25.09633.397-16.136 1.0031.26O·
ATOM1064N ALAA134 23.65833.340-17.867 1.00 30.42N
ATOM1065CA ALAA134 23.00534.618-17.604 1.0030.55 C
ATOM1066CB ALAA134 21.95234.915-18.682 1.00 30.48 C
ATOM1067C ALAA134 22.39134.730-16.189 1.0031.05C
ATOM1068O ALAA134 22.39435.816-15.601 1.00 32.37O
ATOM1069N GLUA135 21.86533.629-15.657 1.00 30.39N
ATOM1070CA GLUA135 21.290 33.602-14.305 1.0029.95 C
ATOM1071CB GLUA135 20.74232.214-13.974 1.0029.41 C
ATOM1072CG GLUA135 19.407 31.874-14.617 1.0029.97 C
ATOM1073CD GLUA135 18.958 30.454-14.297 1.00 28.83 C
ATOM1074OEl GLU A135 17.82530.082-14.646 1.00 30.96O
ATOM1075OE2 GLUA135 19.72529.695 -13.695 1.00 26.29O
ATOM1076C GLUA135 22.25633.994-13.180 1.0030.17C
ATOM1077O GLUA135 21.81934.489-12.159 1.0029.60O
ATOM1078N PHEA136 23.55633.772-13.357 1.0031.36N
ATOM1079CA PHEA136 24.50634.009-12.261 1.00 32.22 C
ATOM1080CB PHEA136 25.04632.675-11.683 1.0031.08C
ATOM1081CG PHEA136 26.10332.022-12.524 1.0029.48C
ATOM1082CDl PHE A136 25.77131.010-13.400 1.0024.38C
ATOM1083CEl PHEA136 26.74430.420-14.199 1.00 25.40C
ATOM1084CZ PHEA136 28.07330.851 -14.118 1.0026.13C
ATOM1085CE2 PHEA136 28.41131.868-13.250 1.0024.90C
ATOM1086CD2 PHEA136 27.44332.438-12.446 1.0025.43C
ATOM1087C PHEA136 25.60135.004-12.605 1.00 34.39C
ATOM1088O PHEA136 26.27935.517-11.712 1.00 35.70O
ATOM1089N LYSA137 25.78835.292-13.894 1.00 37.08N
ATOM1090CA LYSA137 26.70036.368 -14.293 1.00 38.80C
ATOM1091CB LYSA137 27.13936.261 -15.753 1.00 38.69C
ATOM1092CG LYSA137 27.58434.910-16.200 1.0039.17C
ATOM1093CD LYSA137 28.99134.598-15.704 1.00 39.62C
ATOM1094CE LYSA137 29.63733.582 -16.622 1.00 38.86C
ATOM1095NZ LYSA137 30.72132.802-15.946 1.0041.02N
ATOM1096C LYSA137 26.03637.719-14.032 1.0040.49C
ATOM1097O LYS A137 24.81237.800-13.807 1.0040.47O
ATOM1098N THRA138 26.85038.774-14.060 1.0042.59N
ATOM1099CA THRA138 26.47140.065 -13.473 1.0045.10 C [0266]ATOM1100CB THRA13827.442 40.499-12.2951.0045.19C
ATOM1101OGl THRA13828.825 40.332-12.6831.0044.96O
ATOM1102CG2 THRA13827.164 39.684-11.0461.0046.50C
ATOM1103C THRA13826.408 41.233-14.4501.0046.46C
ATOM1104O THRA13825.439 42.029-14.4371.0046.82O
ATOM1105N GLYA13927.456 41.364-15.2621.00 47.50N
ATOM1106CA GLYA13927.743 42.669-15.8531.0048.82C
ATOM1107C GLYA13927.799 42.634-17.3511.00 49.55C
ATOM1108O GLYA13926.770 42.677-18.0161.00 49.40O
ATOM1109N ALAA14029.019 42.554-17.8651.00 50.43N
ATOM1110CA ALAA14029.255 42.520-19.2941.00 50.89C
ATOM1111CB ALAA14030.595 43.122-19.6241.00 50.90C
ATOM1112C ALAA14029.171 41.087-19.7971.0051.28C
ATOM1113O ALAA14028.829 40.848 -20.9591.0051.40O
ATOM1114N GLUA14129.477 40.113-18.9401.0051.10N
ATOM1115CA GLUA14129.286 38.746-19.4171.00 50.54C
ATOM1116CB GLUA14130.454 37.813-19.0801.0050.77C
ATOM1117CG GLUA14130.711 37.534-17.6421.00 52.90C
ATOM1118CD GLUA14131.719 36.404-17.4901.00 55.58C
ATOM1119OEl GLUA14132.448 36.372-16.4671.00 57.03O
ATOM1120OE2GLUA14131.780 35.551 -18.4051.0055.68O
ATOM1121C GLUA14127.873 38.165 -19.2081.0048.91C
ATOM1122O GLUA14127.562 37.130-19.7781.0049.21O
ATOM1123N ARGA14227.030 38.865-18.4441.0047.52N
ATOM1124CA ARGA142 25.592 38.572-18.355 1.0046.44C
ATOM1125CB ARGA14224.967 39.195-17.1011.0046.20C
ATOM1126CG ARGA142 23.568 38.646-16.784 1.0046.91C
ATOM1127CD ARGA142 22.830 39.409-15.686 1.00 47.17C
ATOM1128NE ARGA14221.762 40.241 -16.2221.0048.66N
ATOM1129CZ ARGA14220.470 39.921 -16.2201.0046.13C
ATOM1130NHl ARGA14219.583 40.759-16.7471.00 41.61N
ATOM1131NH2ARGA14220.070 38.782-15.6761.00 46.31N
ATOM1132C ARGA14224.844 39.081 -19.5881.00 45.88C
ATOM1133O ARGA14223.950 38.396 -20.1211.0044.89O
ATOM1134N LYS A14325.201 40.303 -20.0071.0045.45N
ATOM1135CA LYSA14324.679 40.921 -21.2291.0044.80C
ATOM1136CB LYSA14325.113 42.399-21.3521.0045.17C
ATOM1137CG LYS A14326.404 42.685-22.1471.00 45.39C
ATOM1138CD LYSA14326.488 44.172-22.5921.0046.64C
ATOM1139CE LYSA14327.950 44.658 -22.8341.0048.61C
ATOM1140NZ LYSA14328.686 45.119-21.5781.00 51.19N
ATOM1141C LYS A14325.106 40.097 -22.4381.0043.52C
ATOM1142O LYS A14324.357 39.956 -23.3911.0043.37O
ATOM1143N GLUA14426.295 39.517-22.3461.0041.97N
[0267]ATOM1144CAGLU A14426.83738.601 -23.3351.00 40.71CATOM1145CBGLUA14428.28238.334 -22.9571.0040.77C
ATOM1146CGGLUA14429.22138.128 -24.1081.0044.44C
ATOM1147CDGLUA14430.420 37.250 -23.7331.0049.02C
ATOM1148OEl GLUA14430.97637.401 -22.6071.0049.81O
ATOM1149OE2 GLUA14430.80236.405 -24.5781.00 50.95O
ATOM1150CGLUA14426.05637.274 -23.4031.00 39.24C
ATOM1151OGLUA14425.75036.766-24.4911.00 39.86O
ATOM1152NALAA14525.71736.717-22.2421.00 36.93N
ATOM1153CAALAA14525.00035.445 -22.2061.00 34.84C
ATOM1154CBALAA14525.04234.839-20.8171.00 34.24C
ATOM1155CALAA14523.56135.596 -22.7061.00 33.90C
ATOM1156OALAA14523.02834.706 -23.3871.00 32.28O
ATOM1157NALAA14622.94836.736 -22.3731.00 33.53N·
ATOM1158CAALAA14621.56937.019-22.7701.00 33.18C
ATOM1159CBALAA14620.99438.154-21.9491.00 32.99C
ATOM1160CALAA14621.42637.279 -24.2751.0033.14C
ATOM1161OALAA14620.37236.964 -24.8531.00 33.35O
ATOM1162NGLUA14722.47837.801 -24.9131.00 33.64N
ATOM1163CAGLUA14722.48637.959 -26.3791.00 34.41C
ATOM1164CBGLUA14723.64438.811-26.9171.00 35.52C
ATOM1165CGGLU A14724.21739.829 -25.9741.00 40.26C
ATOM1166CDGLUA14723.49941.168 -25.9961.00 46.16C
ATOM1167OElGLUA14722.62941.392 -25.1051.0047.43O
ATOM1168OE2 GLUA14723.82841.999 -26.8861.0048.60O
ATOM1169CGLUA14722.56736.615 -27.0421.00 33.47C
ATOM1170OGLUA14721.81636.366-27.9761.00 34.05O
ATOM1171NSERA 14823.46235.748 -26.5561.00 32.63N
ATOM1172CASERA 14823.60334.407 -27.1041.0031.68C
ATOM1173CBSERA 14824.80233.681 -26.5301.00 33.00C
ATOM1174OGSERA 14826.03934.335 -26.8301.00 33.36O
ATOM1175CSERA 14822.32433.568 -26.9611.0031.32C
ATOM1176OSERA 14821.97032.821 -27.8901.0030.60O
ATOM1177NTHRA14921.63633.714-25.8281.00 30.13N
ATOM1178CATHRA14920.35333.047 -25.5711.0029.43C
ATOM1179CBTtIRA 14919.81133.364-24.1531.0029.15C
ATOM1180OGl THRA14920.82533.108 -23.1881.00 28.43O
ATOM1181CG2 THRA14918.58732.527 -23.8361.0027.44C
ATOM1182CTHRA14919.27833.453 -26.5781.0029.30C
ATOM1183OTHRA14918.60932.596-27.1541.0029.28O
ATOM1184NMETA 15019.12634.769-26.7541.00 29.22N
ATOM1185CAMETA 15018.23135.382-27.7391.00 28.51C
ATOM1186CBMETA 15018.44636.908 -27.7281.0029.95C
ATOM1187CGMETA 15017.45637.758 -28.5911.00 28.36C[0268]ATOM1188SD ΜΕΤΑ 15015.78837.570-28.014 1.00 30.64S
ATOM1189CE ΜΕΤΑ 15015.63738.979 -26.904 1.00 28.51C
ATOM1190C ΜΕΤΑ 15018.46834.830-29.150 1.0027.75C
ATOM1191O ΜΕΤΑ 15017.54434.333 -29.816 1.00 26.30O
ATOM1192N VALA15119.72034.908 -29.580 1.0027.02N
ATOM1193CA VALA15120.15834.392 -30.894 1.0026.27C
ATOM1194CB VALA15121.66334.744-31.122 1.0026.40C
ATOM1195CGl VALA15122.26133.974 -32.284 1.0027.39C
ATOM1196CG2 YALA15121.81236.269 -31.350 1.00 25.04C
ATOM1197C VALA15119.83532.908 -31.090 1.0026.04C
ATOM1198O VALA15119.20932.521 -32.106 1.0026.57O
ATOM1199N ALAA15220.21332.082 -30.107 1.0024.42N
ATOM1200CA ALAA15219.91830.655 -30.139 1.0023.65C
ATOM1201CB ALAA15220.61529.955 -28.957 1.00 22.71C
ATOM1202C ALAA15218.40530.335-30.179 1.00 22.56C
ATOM1203O ALAA15217.94029.549-31.010 1.0021.87O
ATOM1204N TYR A15317.66730.955 -29.252 1.0022.13N
ATOM1205CA TYRA15316.20230.839-29.140 1.0021.75C
ATOM1206CB TYRA15315.68531.543-27.875 1.00 19.60C
ATOM1207CG TYRA15315.82230.748 -26.590 1.0018.98C
ATOM1208CDl TYRA15316.10629.398 -26.606 1.0018.76C
ATOM1209CEl TYRA15316.22028.693 -25.408 1.0019.73C
ATOM1210CZ TYRA15316.04729.345 -24.214 1.0014.36C
ATOM1211OH TYRA15316.08428.631 -23.057 1.0017.23O
ATOM1212CE2 TYRA15315.69430.628 -24.176 1.0011.49C
ATOM1213CD2 TYRA15315.63031.352 -25.347 1.0017.99C
ATOM1214C TYRA15315.38231.333 -30.343 1.0022.00C
ATOM1215O TYRA15314.37830.705 -30.720 1.0020.97O
ATOM1216N LYS A15415.78732.490 -30.853 1.00 22.94N
ATOM1217CA LYS A15415.28133.101 -32.074 1.0025.14C
ATOM1218CB LYS A15415.97534.455 -32.286 1.0025.94C
ATOM1219CG LYSA15415.29635.454 -33.213 1.00 30.45C
ATOM1220CD LYSA15415.43836.904 -32.701 1.00 37.91C
ATOM1221CE LYS A15416.67537.687 -33.228 1.00 41.15C
ATOM1222NZ LYSA15417.84337.870 -32.269 1.0040.29N
ATOM1223C LYS A15415.43532.169-33.285 1.00 24.75C
ATOM1224O LYS A15414.45231.888 -33.974 1.0025.70O
ATOM1225N ALAA15516.63331.657 -33.526 1.00 23.75N
ATOM1226CA ALAA15516.83030.699 -34.602 1.00 23.81C
ATOM1227CB ALAA15518.29830.289 -34.703 1.0024.39C
ATOM1228C ALAA15515.95129.456 -34.448 1.00 23.69C
ATOM1229O ALAA15515.31629.041 -35.411 1.00 23.19O
ATOM1230N ALAA15615.95328.867 -33.237 1.0023.32N
ATOM1231CA ALAA15615.13027.728 -32.892 1.0023.09C
[0269]ATOM1232CB ALAA156 15.370 27.327 -31.427 1.0022.54 CATOM1233C ALAA156 13.624 28.021 -33.171 1.0023.35C
ATOM1234O ALAA156 12.950 27.236-33.819 1.00 25.10O
ATOM1235N GLN A157 13.134 29.162 -32.702 1.00 23.61N
ATOM1236CA GLNA157 11.808 29.656 -32.963 1.0023.58 C
ATOM1237CB GLNA157 11.613 30.993 -32.280 1.0023.98 C
ATOM1238CG GLNA157 10.164 31.445 -32.165 1.0021.91 C
ATOM1239CD GLNA157 10.000 32.858-31.645 1.0023.03 C·
ATOM1240OEl GLNA157 10.506 33.807-32.235 1.0024.08O
ATOM1241NE2GLNA157 9.261 33.011 -30.539 1.00 20.31N
ATOM1242C GLNA157 11.494 29.833 -34.431 1.0024.63C
ATOM1243O GLNA157 10.378 29.499-34.880 1.00 24.69O
ATOM1244N ASPA158 12.429 30.396 -35.189 1.0024.91N
ATOM1245CA ASPA158 12.133 30.630-36.617 1.00 25.51C
ATOM1246CB ASPA158 13.225 31.358-37.393 1.0025.65C
ATOM1247CG ASPA158 13.462 32.752 -36.925 1.00 29.09C
ATOM1248ODl ASPA158 12.528 33.456 -36.442 1.0029.16O
ATOM1249OD2ASPA158 14.630 33.147-37.098 1.0031.24O
ATOM1250C ASPA158 11.952 29.311 -37.271 1.0024.43C
ATOM1251O ASPA158 10.991 29.156-37.963 1.0026.95O
ATOM1252N ILE A159 12.893 28.389 -37.057 1.0024.22N
ATOM1253CA ILEA 159 12.839 27.006 -37.549 1.0024.17C
ATOM1254CB ILEA 159 14.170 26.229 -37.331 1.0024.68C
ATOM1255CGl ILEA 159 15.334 26.895 -38.054 1.00 23.27C
ATOM1256CDl ILEA 159 16.690 26.446 -37.522 1.0018.91C
ATOM1257CG2 ILEA 159 14.090 24.810-37.816 1.00 22.61C
ATOM1258C ILEA 159 11.599 26.184 -37.105 1.0024.56C
ATOM1259O ILEA 159 10.975 25.472 -37.947 1.0025.00O
ATOM1260N ALAA160 11.234 26.261 -35.832 1.0022.85N
ATOM1261CA ALAA160 10.016 25.591 -35.365 1.00 22.81C
ATOM1262CB ALAA160 9.927 25.615-33.856 1.0021.28C
ATOM1263C ALAA160 8.716 26.114-35.987 1.0024.30C
ATOM1264O ALAA160 7.751 25.346-36.164 1.0024.11O
ATOM1265N LEUA161 8.656 27.421 -36.262 1.0025.51N
ATOM1266CA LEUA161 7.485 27.970-36.861 1.0026.61C
ATOM1267CB LEUA161 7.395 29.472 -36.679 1.00 27.12C
ATOM1268CG LEUA161 6.011 29.557-36.010 1.00 30.36C
ATOM1269CDl LEUA161 5.911 30.608 -34.820 1.00 32.02C
ATOM1270CD2 LEUA161 4.802 29.646 -37.020 1.0026.82C
ATOM1271C LEUA161 7.393 27.588 -38.302 1.0027.20C
ATOM1272O LEUA161 6.298 27.389 -38.792 1.0028.60O
ATOM1273N ALA A162 8.537 27.493 -38.983 1.0027.31N
ATOM1274CA ALAA162 8.586 27.026 -40.387 1.00 25.97C
ATOM1275CB ALAA162 9.956 27.194 -40.965 1.00 24.25C
[0270]ATOM1276C ALAA1628.188 25.582 -40.5051.0026.54CATOM1277O ALAA1627.370 25.234 -41.3651.0026.57O
ATOM1278N ASPA1638.771 24.727 -39.6621.00 26.50N
ATOM1279CA ASPA163 8.687 23.294 -39.8951.0026.96C
ATOM1280CB ASPA16310.080 22.717-40.1941.0027.77C
ATOM1281CG ASPA16310.532 22.965 -41.6591.00 29.59C
ATOM1282ODl ASPA1639.821 23.653 -42.4541.0031.63O
ATOM1283OD2ASPA16311.615 22.468 -42.0041.0031.55O
ATOM1284C ASPA1637.920 22.390-38.9291.00 26.94C
ATOM1285O ASPA1637.569 21.269-39.3091.00 24.67O
ATOM1286N LEUA1647.648 22.855 -37.7031.0027.13N
ATOM1287CA LEUA164 7.025 21.968 -36.7021.0026.88C
ATOM1288CB LEUA164 7.795 21.921 -35.3661.0027.30C
ATOM1289CG LEUA164 9.262 21.506 -35.3521.0025.71C
ATOM1290CDl LEUA1649.769 21.699 -33.9501.00 21.33C
ATOM1291CD2 LEUA1649.470 20.053 -35.8691.0021.26C
ATOM1292C LEUA1645.641 22.438 -36.4321.00 27.12C
ATOM1293O LEUA1645.351 23.611 -36.5951.00 26.71O
ATOM1294N ALAA1654.785 21.498 -36.0381.0028.10N
ATOM1295CA ALAA165 3.386 21.765 -35.7941.00 28.21C
ATOM1296CB ALAA165 2.573 20.435 -35.7221.0028.95C
ATOM1297C ALAA1653.346 22.514-34.4941.00 28.17C
ATOM1298O ALAA1654.262 22.347 -33.6641.00 29.04O
ATOM1299N PROA 1662.342 23.397-34.3301.0027.92N
ATOM1300CA PRO A166 2.240 24.203 -33.1101.00 27.64C
ATOM1301CB PROA 166 1.029 25.096 -33.3431.00 27.79C
ATOM1302CG PROA 166 0.263 24.418 -34.4701.0028.88C
ATOM1303CD PRO A166 1.280 23.697 -35.3001.0028.11C
ATOM1304C PRO A1662.115 23.402 -31.8161.00 27.46C
ATOM1305O PRO A1662.550 23.886-30.7471.0027.07O
ATOM1306N THRA1671.547 22.195 -31.9361.00 25.81N
ATOM1307CA THRA167 1.362 21.248 -30.8551.0025.93C
ATOM1308CB THRA167 0.291 20.200 -31.2551.00 26.64C
ATOM1309OGl THRA1670.681 19.594 -32.4981.00 27.75O
ATOM1310CG2 THRA167-1.095 20.827-31.4151.00 24.49C
ATOM1311C THRA1672.641 20.453 -30.5441.0025.60C
ATOM1312O THRA1672.704 19.729 -29.5401.0026.74O
ATOM1313N HISA1683.642 20.524 -31.4231.0024.51N
ATOM1314CA HISA1684.842 19.707 -31.2931.00 23.17C
ATOM1315CB HISA1685.838 19.994-32.4451.0023.16C
ATOM1316CG HISA1686.834 18.907-32.6151.00 23.18C
ATOM1317NDl HISA1687.703 18.544 -31.6091.00 28.69N
ATOM1318CEl HIS A1688.411 17.500 -31.9941.00 28.36C
ATOM1319NE2HISA1688.017 17.161 -33.2071.0027.72N
[0271]ATOM1320CD2HISA1687.021 18.015-33.613 1.0026.96CATOM1321C HIS A1685.498 20.043 -29.952 1.00 22.64C
ATOM1322O HIS A1685.619 21.222 -29.664 1.0022.16O
ATOM1323N PROA 1695.840 19.019-29.113 1.0022.39N
ATOM1324CA PRO A1696.445 19.205 -27.794 1.0022.40C
ATOM1325CB PROA 1696.618 17.782 -27.282 1.00 22.52C
ATOM1326CG PROA 1695.545 17.020 -27.991 1.00 22.45C·
ATOM1327CD PROA 1695.582 17.592 -29.359 1.0021.41C
ATOM1328C PRO A1697.776 19.907 -27.793 1.0023.08C
ATOM1329O PRO A1698.127 20.515-26.798 1.0024.52O
ATOM1330N ILE A1708.508 19.843 -28.899 1.0023.12N
ATOM1331CA ILE A1709.816 20.503 -28.988 1.0021.09C
ATOM1332CB ILE A17010.669 19.774 -30.037 1.0020.53C
ATOM1333CGl ILE A17011.328 18.548 -29.391 1.0016.40C
ATOM1334CDl ILEA 17012.051 17.653 -30.404 1.00 19.31C
ATOM1335CG2ILEA17011.669 20.674-30.706 1.0020.79C
ATOM1336C ILEA 1709.580 22.006-29.220 1.0021.75C
ATOM1337O ILEA 17010.222 22.888 -28.571 1.0021.51O
ATOM1338N ARGA1718.550 22.285 -30.037 1.0020.58N
ATOM1339CA ARGA1718.172 23.628 -30.401 1.0019.97C
ATOM1340CB ARGA1717.323 23.629-31.684 1.0019.95C
ATOM1341CG ARGA1716.669 24.956 -31.943 1.0019.32C
ATOM1342CD ARGA1716.125 25.164-33.349 1.0018.50C
ATOM1343NE ARGA1715.232 26.323 -33.334 1.0018.85N
ATOM1344CZ ARGA1714.341 26.626-34.280 1.00 19.52C
ATOM1345NHl ARGA1714.236 25.871 -35.348 1.0015.21N
ATOM1346NH2ARGA1713.554 27.691 -34.161 1.0021.03N
ATOM1347C ARGA1717.477 24.284 -29.209 1.0019.83C
ATOM1348O ARGA1717.647 25.497 -28.981 1.0020.35O
ATOM1349N LEU A1726.754 23.493 -28.409 1.0018.56N
ATOM1350CA LEUA1726.200 24.023 -27.147 1.0017.79C
ATOM1351CB LEU A1725.114 23.112-26.617 1.0017.60C
ATOM1352CG LEUA1723.818 23.040 -27.436 1.0018.32C
ATOM1353CDl LEUA1722.904 21.913-26.928 1.0017.11C
ATOM1354CD2 LEUA1723.086 24.374 -27.416 1.0014.15C
ATOM1355C LEU A1727.244 24.293 -25.997 1.0018.39C
ATOM1356O LEU A1727.051 25.203 -25.206 1.00 18.69O
ATOM1357N GLYA1738.294 23.488 -25.897 1.0018.94N
ATOM1358CA GLYA1739.306 23.637 -24.823 1.0020.80C
ATOM1359C GLYA17310.253 24.752 -25.147 1.00 20.91C
ATOM1360O GLYA17310.815 25.399 -24.246 1.0024.17O
ATOM1361N LEU A17410.464 24.961 -26.444 1.0021.30N
ATOM1362CA LEUA17411.103 26.180 -26.953 1.0020.45C
ATOM1363CB LEUA17411.306 26.146 -28.492 1.0019.79C[0272]
ATOM1408CA VALA18011.09732.119-19.0831.0025.15C
ATOM1409CB VALA18011.53530.694-18.6341.00 25.47C
ATOM1410CGl VALA18012.53130.795-17.4771.00 25.51C
ATOM1411CG2VALA18010.33929.851 -18.2111.00 24.40C
ATOM1412C VALA18012.28533.069-19.149LOO 25.23C
ATOM1413O VALA18012.44533.901 -18.2801.00 25.72O
ATOM1414N PHEA18113.08232.947 -20.2021.0026.15N
ATOM1415CA PHEA18114.11133.944-20.5961.0026.66C·ATOM1416CB PHEA18114.77633.514-21.9211.00 26.55C
ATOM1417CG PHEA18115.67234.539-22.5161.00 29.23C
ATOM1418CDl PHEA18116.85934.912-21.8641.0027.66C
ATOM1419CEl PHEA18117.69035.859 -22.4191.0027.76C
ATOM1420CZ PHEA18117.35536.452 -23.6201.0028.56C
ATOM1421CE2 PHEA18116.17436.091 -24.2821.0030.03C
ATOM1422CD2 PHEA18115.34735.142-23.7351.0028.21C
ATOM1423C PHEA18113.64035.422 -20.5971.0027.11C
ATOM1424O PPffiA 18114.28436.313-19.9591.0024.60O
ATOM1425N TYR A18212.50035.692-21.2311.0027.22N
ATOM1426CA TYR A18211.88137.041 -21.1011.0028.89C
ATOM1427CB TYRA18210.64137.260 -21.9911.00 28.18C
ATOM1428CG TYRA18211.03137.606 -23.3831.0029.73C
ATOM1429CDl TYRA18211.42638.899-23.7091.00 29.95C
ATOM1430CEl TYRA18211.82339.220 -25.0011.0031.08C
ATOM1431CZ TYRA18211.86038.238-25.9691.00 28.96C
ATOM1432OH TYRA18212.25638.545 -27.2401.00 27.96O
ATOM1433CE2TYRA18211.48836.937 -25.6671.00 32.08C
ATOM1434CD2 TYRA18211.07836.623 -24.3771.00 31.15C
ATOM1435C TYR A18211.55837.409-19.6701.0029.02C
ATOM1436O TYRA18211.86338.503-19.2241.00 28.97O
ATOM1437N TYR A18310.94936.497-18.9451.00 30.39N
ATOM1438CA TYRA18310.56736.794-17.5601.0031.83C
ATOM1439CB TYRA1839.60135.734-17.0411.00 32.25C
ATOM1440CG TYRA1838.92436.126-15.7451.0033.94C
ATOM1441CDl TYRA1837.82737.007-15.7451.00 32.57C
ATOM1442CEl TYRA1837.19637.381 -14.5441.00 33.17C
ATOM1443CZ TYRA1837.66036.869-13.3211.00 34.98C
ATOM1444OH TYRA1837.02337.228-12.1421.00 37.01O
ATOM1445CE2TYRA1838.75535.996-13.2831.0036.60C
ATOM1446CD2TYRA1839.38335.622 -14.5091.00 35.92C
ATOM1447C TYRA18311.78036.960-16.5961.00 32.42C
ATOM1448O TYRA18311.89637.998 -15.9211.0031.91O
ATOM1449N GLU A18412.67135.956-16.5621.00 32.43N
ATOM1450CA GLUA18413.71435.881 -15.5471.00 32.56 C
ATOM1451CB GLU A18414.03834.423 -15.1681.00 33.15C
[0274]ATOM1452CG GLU A184 12.808 33.509-15.207 1.00 37.16CATOM1453CD GLU A184 12.828 32.342 -14.220 1.00 39.10C
ATOM1454OEl GLUA18412.084 32.459-13.225 1.0041.15O
ATOM1455OE2GLUA18413.535 31.316-14.440 1.00 37.86O
ATOM1456C GLU A18414.984 36.632-15.892 1.0032.39C
ATOM1457O GLU A18415.611 37.208-15.006 1.00 32.10O
ATOM1458N ILEA 18515.368 36.643-17.165 1.0031.83N ATOM1459CA ILE A18516.634 37.259-17.548 1.0031.60C
ATOM1460CB ILEA 18517.441 36.408-18.598 1.0031.43C
ATOM1461CGl ILE A18517.887 35.059-17.987 1.00 30.71C
ATOM1462CDl ILEA 18518.626 35.155-16.574 1.00 24.53C
ATOM1463CG2 ILEA 18518.639 37.182-19.154 1.00 30.46C
ATOM1464C ILEA 18516.440 38.703 -17.990 1.00 32.26C
ATOM1465O ILE A18517.200 39.614-17.581 1.0031.24O
ATOM1466N LEUA18615.403 38.914-18.787 1.0031.64N
ATOM1467CA LEUA18615.146 40.215 -19.344 1.00 32.08C
ATOM1468CB LEUA18614.689 40.082 -20.787 1.0031.05C
ATOM1469CG LEUA18615.737 40.133 -21.898 1.0031.55C
ATOM1470CDl LEUA18617.179 39.735-21.502 1.00 31.21C
ATOM1471CD2 LEUA18615.242 39.349 -23.111 1.00 27.46C
ATOM1472C LEU A18614.146 41.032-18.542 1.00 32.95C
ATOM1473O LEUA18613.876 42.179-18.897 1.00 33.61O
ATOM1474N ASN A18713.593 40.447-17.482 1.00 33.34N
ATOM1475CA ASNA18712.579 41.106-16.672 1.00 34.32C
ATOM1476CB ASNA18713.229 42.161 -15.750 1.00 34.84C
ATOM1477CG ASNA18714.383 41.592-14.922 1.0037.19C
ATOM1478ODl ASNA18715.528 42.032-15.050 1.0038.54O
ATOM1479ND2ASNA18714.089 40.590-14.100 1.0039.52N
ATOM1480C ASN A18711.435 41.736-17.494 1.00 33.60C
ATOM1481O ASNA18711.069 42.895 -17.274 1.00 34.14O
ATOM1482N SERA 18810.874 40.965-18.426 1.00 33.40N
ATOM1483CA SERA 1889.859 41.443-19.359 1.0031.75C
ATOM1484CB SERA 18810.414 41.480-20.776 1.00 31.65C
ATOM1485OG SERA 18811.487 42.374 -20.909 1.0032.60O
ATOM1486C SERA 1888.629 40.538-19.328 1.0031.63C
ATOM1487O SERA 1888.365 39.823 -20.307 1.00 30.68O
ATOM1488N PROA 1897.871 40.586-18.212 1.0031.62N
ATOM1489CA PROA 1896.638 39.858 -17.892 1.00 30.97C
ATOM1490CB PROA 1896.059 40.651 -16.713 1.0031.28C
ATOM1491CG PROA 1896.971 41.914-16.582 1.00 32.27C
ATOM1492CD PROA 1898.271 41.438-17.072 1.0031.74C
ATOM1493C PROA 1895.607 39.828-18.989 1.0031.23C
ATOM1494O PRO A1895.010 38.773 -19.242 1.0031.10O
ATOM1495N ASP A1905.399 40.998-19.585 1.0031.28N[0275]ATOM1496 CA ASPA1904.503 41.224-20.6811.0031.86C
ATOM1497 CB ASPA1904.403 42.714-20.9581.00 32.34C
ATOM1498CG ASPA1903.252 43.340-20.2471.00 34.58C
ATOM1499 ODl ASPA1902.713 42.717-19.2941.00 36.00O
ATOM1500 OD2 ASPA1902.883 44.464 -20.6401.0040.15O
ATOM1501C ASPA1904.911 40.515-21.9371.00 30.84C
ATOM1502O ASPA1904.089 39.892 -22.5731.00 30.14O
ATOM1503N ARGA1916.185 40.649-22.2921.0031.25N·ATOM1504CA ARGA1916.749 39.952 -23.455 1.00 30.95C
ATOM1505CB ARGA1918.150 40.494 -23.791 1.0030.81C
ATOM1506CG ARGA1918.193 41.959-24.270 1.0031.94C
ATOM1507CD ARGA1919.667 42.447-24.381 1.0034.47C
ATOM1508NE ARGA1919.886 43.897 -24.211 1.00 42.77N
ATOM1509CZ ARGA19110.981 44.428 -23.638 1.00 47.98C
ATOM1510NHl ARGA19111.956 43.641 -23.1661.0048.82N
ATOM1511NH2 ARGA19111.113 45.748 -23.5301.0048.75N
ATOM1512C ARGA1916.762 38.437-23.2121.0029.06C
ATOM1513O ARGA1916.403 37.620-24.1111.0027.84O
ATOM1514N ALAA1927.149 38.073 -21.9871.00 27.54N
ATOM1515CA ALAA1927.054 36.691 -21.5141.0027.19C
ATOM1516CB ALAA1927.523 36.601 -20.0791.00 26.47C
ATOM1517C ALAA1925.618 36.116-21.6611.0027.12C
ATOM1518O ALAA1925.425 35.038-22.1951.0027.78O
ATOM1519N CYSA1934.627 36.867 -21.2021.00 27.00N
ATOM1520CA CYS A1933.273 36.414-21.1551.00 27.74C
ATOM1521CB CYS A1932.412 37.402 -20.3731.00 27.45C
ATOM1522SG CYS A1932.437 37.062-18.6121.0029.11S
ATOM1523C CYSA1932.709 36.198 -22.5401.0027.31C
ATOM1524O CYSA1932.204 35.153 -22.8021.00 27.93O
ATOM1525N ASNA1942.794 37.166 -23.4411.00 28.86N
ATOM1526CA ASNA1942.209 36.912 -24.7861.00 29.43C
ATOM1527CB ASN A1941.761 38.184 -25.4911.0031.48C
ATOM1528CG ASNA1942.669 39.346 -25.2161.0036.18C
ATOM1529ODl ASNA1943.787 39.404-25.7221.0041.72O
ATOM1530ND2 ASNA1942.189 40.293 -24.4221.00 38.86N
ATOM1531C ASN A1942.987 35.967 -25.6981.0028.22C
ATOM1532O ASNA1942.401 35.336 -26.5601.00 28.55O
ATOM1533N LEUA1954.292 35.828 -25.4791.00 26.56N
ATOM1534CA LEUA1955.061 34.780-26.1671.0026.40C
ATOM1535CB LEUA1956.570 34.911-25.8951.00 26.09C
ATOM1536CG LEUA1957.561 34.279-26.8701.0027.19C
ATOM1537CDl LEU A1958.982 34.667 -26.4451.00 25.25C
ATOM1538CD2 LEUA1957.411 32.811 -26.9041.00 23.89C
ATOM1539C LEUA1954.541 33.391 -25.7781.0025.87C
[0276]ATOM 1598 CA ALAA203 -1.329 24.702-29.959 1.00 25.94 O ATOM 1599 CB ALAA203 -0.469 24.230-280017 roosw O ATOM 1600 C ALAA203 -2.8M 24.347-29.703 1.00 27.85 n ATOM 1601 O ALAA203 -3.271 23.262 _30.0M 100 27.58 O ATOM 】602 N ILEA204 -3.557 25.226-29023 100 29.39^ ATOM 1603 CA ILEA204 -4.977 24.981 -28.722 100 30.67 n ATOM 1604 CB ILEA204 -5.568 26.119 丨27.826 1.00 30.56 n ATOM 1605 CG11LEA204 -5.165 25.989-26.353 100 27.25 C ATOM 1606 CD1ILWA204 -5.712 24.785-25.6U lbo 28.41 n ATOM 1607 CG2ILEA204 -7.075 26.182-27.942 1.00 30.81 n ATOM 1608 C ILEA204 -5.807 24.818-30.026 100 32.27 C ATOM 1609 O ILEA204 -6.728 21976-30.119 1.00 33.52 O ATOM 1610¾SERA205 -5.444 25.613-31034 100 33.09^ ATOM 1611 CA SERA205 -6.092 25.598,32.323 1.00 33.63 C ATOM 1612 Ca SERA205 -5.643 260007-33.185 1.00 33.68 O ATOM 1613 OG SERA205 -4.43OC2σ\560-33.9S100 33.76 O· ATOM 16U n SERA205 ^ 24.285-33.083 1.0034.36 C ATOM 1615 O SERA205 .6.679 24027-34.023 1.00 35.72 〇 ATOM 1616 ^ GLUA206 -4.938 23.458-32.710 1.00 34.11 M ATOM 1617OA GLUA206 -4.749 22.143-33.358 1.00 32.86 C ATOM 16SO» GLUA206 —3.436 22.105—34139 一00 32.61 C ATOM 1619 no GLCA206 -3.353 23.144-35.270 1.00 33.96 O ATOM 1620 CD GLUA206 -2.122 22.959-36.165 M0033 400O ATOM 1621 OE1GLUA2G6 -1.461 21.907-36019 100 32.25 O ATOM 1622 OE2GLU>206 -10021 23.864-37.007 1.00 33.52 O ATOM 1623 C GLUA206 _4.83 办 20.927-32.416 1.00 32.46 O ATOM 1624 O GLU A 206 -4.734 19.787-32.877 1.00 32.31 O ATOM 1625¾LEUA207 -5034 21.150-31.120 1.00 31.42 Z ATOM 1626 CA LEUA207 -4.930 20.058-30.148 1.00 32.15 n ATOM 1627 CB UEUA207 丨5.123 20.572-28.735 1.00 30.86 O
〔027s
62ATOM1628CG LEUA207 -4.636 19.736-27.5561.00 32.38C
ATOM1629CD1LEUA207 -5.100 20.433 -26.2961.0031.59C
ATOM1630CD2LEUA207 -3.087 19.536 -27.5301.00 28.80C
ATOM1631C LEU A 207 -5.893 18.897 -30.4321.00 32.88C ATOM1632O LEU A 207 -5.573 17.754 -30.1621.00 33.47O
ATOM1633N ASPA 208 -7.051 19.196 -31.0001.00 34.52N
ATOM1634CA ASPA208 -8.069 18.169-31.2781.00 35.87C
ATOM1635CB ASPA208 -9.485 18.745 -31.1321.00 36.49C
ATOM1636CG ASP A 208 -9.755 19.908 -32.0601.00 39.58C
ATOM1637ODl ASP A 208-10.961 20.182 -32.2831.0043.14O
ATOM1638OD2 ASPA 208 -8.790 20.564 -32.5431.0042.21O
ATOM1639C ASPA 208 -7.939 17.403-32.5951.00 35.44C
ATOM1640O ASP A 208 -8.780 16.545 -32.8961.00 36.31O
ATOM1641N THRA 209 -6.897 17.694-33.3671.00 35.00N
ATOM1642CA THRA 209 -6.564 16.914-34.5631.00 34.35C
ATOM1643CB THRA 209 -5.891 17.786 -35.6541.00 34.72C
ATOM1644OGl THRA 209 -4.635 18.316-35.1661.00 36.35O
ATOM1645CG2 THRA 209 -6.795 18.894-36.1041.00 32.66C
ATOM1646C THR A 209 -5.611 15.766-34.2331.00 34.41C
ATOM1647O THR A 209 -5.336 14.908 -35.0721.00 34.66O
ATOM1648N LEU A 210 -5.106 15.743 -33.0011.00 33.72N
ATOM1649CA LEUA210 -4.028 14.850 -32.6371.00 32.81C
ATOM1650CB LEUA210 -3.179 15.431 -31.4811.0031.90C
ATOM1651CG LEUA210 -2.348 16.693 -31.6521.0029.93C
ATOM1652CDl LEUA210 -1.515 16.934 -30.3901.0022.84C
ATOM1653CD2LEUA210 -1.472 16.571 -32.8981.0031.42C
ATOM1654C LEUA210 -4.614 13.568 -32.1631.00 33.14C
ATOM1655O LEU A 210 -5.659 13.579-31.5181.00 33.57O
ATOM1656N GLYA211 -3.907 12.474-32.4441.00 33.56N
ATOM1657CA GLYA 211 -4.169 11.180 -31.8381.00 34.12C
ATOM1658C GLYA211 -3.818 11.239-30.3701.0034.95C
ATOM1659O GLYA 211 -3.267 12.229-29.9081.00 34.50O
ATOM1660N GLUA212 -4.107 10.155 -29.6571.00 35.55N
ATOM1661CA GLUA212 -4.127 10.129-28.204 1.00 36.87C
ATOM1662CB GLUA212 -4.895 8.879 -27.7441.00 37.32C
ATOM1663CG GLUA212 -4.981 8.685 -26.2501.00 39.21C
ATOM1664CD GLUA212 -5.729 9.799 -25.5641.0041.73C
ATOM1665OE1GLUA212 -5.390 10.079-24.3921.0041.78O
ATOM1666OE2GLUA212 -6.643 10.393 -26.2001.0043.35O
ATOM1667C GLU A 212 -2.772 10.253 -27.4701.00 37.03C
ATOM1668O GLUA212 -2.667 11.079-26.5461.00 37.77O
ATOM1669N GLUA 213 -1.791 9.405 -27.8201.00 37.44N
ATOM1670CA GLUA213 -0.371 9.527 -27.3611.00 38.79C
ATOM1671CB GLUA213 0.577 8.556 -28.1031.00 38.15C
[0279]ATOM1672CG GLU A 2130.751 7.150 -27.504 1.0041.67CATOM1673CD GLUA 2131.912 6.292-28.140 1.0042.15C
ATOM1674OEl GLUA2132.733 6.808 -28.9441.0047.68O
ATOM1675OE2GUJA2132.017 5.080 -27.8071.0045.35O
ATOM1676C GLUA2130.133 10.935 -27.649 1.00 37.59C
ATOM1677O GLU A 2130.754 11.577-26.795 1.00 38.54O
ATOM1678N SERA214-0.117 11.390-28.8761.00 36.25N ATOM1679CA SERA2140.307 12.708 -29.316 1.00 35.29C
ATOM1680CB SERA 214-0.017 12.895 -30.7921.00 34.89C
ATOM1681OG SERA 2140.657 14.024-31.300 1.00 34.91O
ATOM1682C SERA214-0.316 13.818-28.4601.00 34.63C
ATOM1683O SERA2140.384 14.708 -27.9431.00 34.88O
ATOM1684N TYRA215-1.621 13.751-28.2881.0033.15N
ATOM1685CA TYRA215-2.304 14.686 -27.396 1.00 33.54C
ATOM1686CB TYRA215-3.797 14.410-27.335 1.00 33.03C
ATOM1687CG TYRA215-4.479 14.873 -26.072 1.00 32.93C
ATOM1688CDl TYRA215-4.950 16.182 -25.9371.00 32.88C
ATOM1689CE1TYRA215-5.598 16.589-24.7571.00 32.81C
ATOM1690CZ TYRA215-5.767 15.673 -23.7161.0032.66C
ATOM1691OH TYRA215-6.399 16.029-22.551 1.00 32.82O
ATOM1692CE2TYRA215-5.304 14.384 -23.8411.00 32.31C
ATOM1693CD2TYRA215-4.677 13.990 -25.0151.00 32.45C
ATOM1694C TYRA215-1.721 14.752-25.9941.00 33.57C
ATOM1695O TYRA 215-1.611 15.841 -25.4481.00 34.44O
ATOM1696N LYS A 216-1.354 13.601 -25.4351.00 33.86N
ATOM1697CA LYSA216-0.849 13.508 -24.0761.0034.55C
ATOM1698CB LYSA216-0.807 12.044-23.6011.00 35.31C
ATOM1699CG LYSA216-2.185 11.345 -23.4561.0037.45C
ATOM1700CD LYS A 216-2.280 10.700 -22.0631.0042.83C
ATOM1701CE LYSA216-2.181 9.152-22.0461.0045.58C
ATOM1702NZ LYSA216-1.012 8.553 -22.7561.0047.17N
ATOM1703C LYSA2160.554 14.122 -23.9721.00 34.40C
ATOM1704O LYS A 2160.900 14.701 -22.9491.00 33.22O
ATOM1705N ASPA2171.338 13.943 -25.0501.00 34.61N
ATOM1706CA ASPA2172.677 14.502-25.2321.00 33.69C
ATOM1707CB ASPA2173.324 13.941 -26.5031.0034.10C
ATOM1708CG ASPA2173.949 12.559 -26.3031.0035.25C
ATOM1709ODl ASPA2174.140 12.106 -25.1451.00 35.03O
ATOM1710OD2ASPA2174.274 11.923 -27.3321.00 38.96O
ATOM1711C ASPA2172.634 16.012 -25.3261.00 33.25C
ATOM1712O ASPA2173.465 16.700 -24.7201.00 33.93O
ATOM1713N SERA2181.681 16.539-26.0941.0031.51N
ATOM1714CA SERA2181.549 17.991 -26.2401.0029.88C
ATOM1715CB SERA2180.574 18.342-27.3691.00 30.17C
[0280]ATOM1716OG SERA 218 0.970 17.750 -28.598 1.00 29.27OATOM1717C SERA218 1.043 18.542-24.919 1.0029.01C
ATOM1718O SERA218 1.633 19.445-24.344 1.00 28.42O
ATOM1719N THRA219-0.024 17.947-24.410 1.00 28.64N
ATOM1720CA THRA219 -0.692 18.429 -23.205 1.0028.67C
ATOM1721CB THRA 219-1.782 17.452-22.801 1.00 28.90C
ATOM1722OG1THRA219-2.855 17.543 -23.773 1.00 30.72O·ATOM1723CG2THRA219-2.312 17.752-21.400 1.0030.16C
ATOM1724C THRA 219 0.301 18.721 -22.075 1.0028.38C
ATOM1725O THRA219 0.100 19.613 -21.286 1.00 28.38O
ATOM1726N LEUA 220 1.393 17.993 -22.047 1.0028.36N
ATOM1727CA LEU A 220 2.309 18.044-20.918 1.0028.16C
ATOM1728CB LEU A 220 3.238 16.814-20.951 1.00 28.04C
ATOM1729CG LEUA220 4.208 16.447-19.811 1.00 30.68C
ATOM1730CDl LEU A 220 4.980 17.640-19.223 1.00 32.34C
ATOM1731CD2LEUA220 3.517 15.701 -18.698 1.00 32.19C
ATOM1732C LEU A 2203.105 19.350 -20.867 1.00 26.77C
ATOM1733O LEU A 220 3.351 19.896-19.794 1.0027.32O
ATOM1734N ILEA2213.510 19.858-22.017 1.0024.97N
ATOM1735CA ILE A 2214.233 21.130-22.039 1.0024.36C
ATOM1736CB ILE A 2215.160 21.211 -23.256 1.00 24.27C
ATOM1737CGl ILE A2216.128 20.022 -23.215 1.00 24.08C
ATOM1738CD1ILEA2216.776 19.843 -24.491 1.00 25.26C
ATOM1739CG2ILEA2215.905 22.512-23.265 1.0024.49C
ATOM1740C ILE Λ 2213.277 22.313-22.017 1.00 24.69C
ATOM1741O ILE A 2213.609 23.420 -21.531 1.00 22.70O
ATOM1742N MET A 222 2.076 22.055 -22.546 1.00 23.34N
ATOM1743CA MET A 222 1.000 22.990 -22.545 1.00 23.44 C
ATOM1744CB MET A 222-0.173 22.406 -23.387 1.00 23.11C
ATOM1745CG MET A 222 -0.034 22.701 -24.869 1.0018.37C
ATOM1746SD MET A 222-1.369 21.915-25.806 1.00 26.08S
ATOM1747CE MET A 222-2.416 23.361 -25.799 1.0016.08C
ATOM1748C MET A 222 0.548 23.340-21.129 1.0023.44C
ATOM1749O ΜΕΤΛ222 0.256 24.481 -20.852 1.0024.63O
ATOM1750N GLNA 223 0.453 22.370-20.229 1.0024.75N
ATOM1751CA GLN A 223 0.112 22.692-18.842 1.00 25.30C
ATOM1752CB GLN A 223-0.390 21.444-18.105 1.00 26.17C
ATOM1753CG GLN A 223 0.491 20.241 -18.133 1.00 30.20C
ATOM1754CD GLN A 223-0.250 18.968-17.777 1.00 33.47C
ATOM1755OEl GLNA 223-1.480 18.945-17.712 1.0036.16O
ATOM1756NE2GLNA223 0.492 17.896-17.586 1.0034.16N
ATOM1757C GLN A 223 1.253 23.418-18.071 1.0024.94C
ATOM1758O GLNA 223 1.040 24.061 -17.066 1.0025.49O
ATOM1759N LEU A2242.463 23.364-18.582 1.0025.35N
[0281]ATOM1760CA LEU A 2243.56424.166-17.9981.00 24.70CATOM1761CB LEU A 2244.92923.563-18.3621.0023.65C
ATOM1762CG LEU A 2245.22422.129-17.9581.0025.24C
ATOM1763CDl LEU A2246.52721.653-18.5691.0028.63C
ATOM1764CD2LEUA2245.21821.956-16.4501.0024.72C
ATOM1765C LEU A 2243.45925.595-18.4761.00 24.39C
ATOM1766O LEU A 2243.69126.509-17.6971.0025.41O
ATOM1767N LEU A2253.11225.788 -19.7581.00 24.08N
ATOM1768CA LEU A2252.80727.123 -20.3181.00 23.73C
ATOM1769CB LEU A 2252.48727.039-21.8351.0023.66C
ATOM1770CG LEU A 2253.40127.528 -23.0011.0024.47C
ATOM1771CDl LEUA2253.53826.477 -24.1501.0021.09C
ATOM1772CD2 LEU A 2254.81328.043 -22.5961.0019.33C
ATOM1773C LEU A 2251.68727.829-19.5261.00 23.44C
ATOM1774O LEU A 2251.88828.957-18.9751.00 23.52O
ATOM1775N ARG A 2260.52527.163-19.4711.0022.55N
ATOM1776CA ARG A 226-0.62127.511 -18.6081.00 21.61C
ATOM1777CB ARG A 226-1.67326.371 -18.7081.00 22.25C
ATOM1778CG ARG A 226-2.97226.670-17.936 1.0021.77C
ATOM1779CD ARG A 226-3.64125.413-17.4311.00 21.63C
ATOM1780NE ARG A 226-2.83324.637-16.5001.0015.92N
ATOM1781CZ ARG A 226-2.89523.321 -16.4011.0020.96C
ATOM1782NHl ARG A 226-3.75622.612-17.1681.0019.21N
ATOM1783NH2ARGA226-2.12222.719-15.5281.0017.61N
ATOM1784C ARG A 226-0.37327.849-17.1061.0021.76C
ATOM1785O ARG A 226-1.01728.756-16.5971.0021.74O
ATOM1786N ASP A 2270.50727.124-16.4021.00 21.37N
ATOM1787CA ASPA 2270.78127.385 -14.9861.0022.50C
ATOM1788CB ASP A 2271.39426.169-14.2771.0022.48C
ATOM1789CG ASPA 2270.45124.927-14.2511.0026.65C
ATOM1790ODl ASPA227-0.68924.975 -14.7591.00 26.53O
ATOM1791OD2 ASPA 2270.87423.861 -13.7391.00 32.11O
ATOM1792C ASPA2271.68028.628-14.8241.00 22.93C
ATOM1793O ASPA2271.40629.498-14.0241.00 24.16O
ATOM1794N ASN A 2282.73028.734-15.6201.0023.45N
ATOM1795CA ASN A2283.40630.011 -15.8201.0024.00C
ATOM1796CB ASN A 2284.43329.872-16.9411.0023.87C
ATOM1797CG ASN A 2285.65329.098-16.4911.00 24.29C
ATOM1798ODl ASNA2285.72728.699-15.3391.0027.20O
ATOM1799ND2ASNA2286.61228.873 -17.3951.00 24.43N
ATOM1800C ASN A 2282.49731.203-16.0951.0024.10C
ATOM1801O ASN A 2282.51232.189-15.3471.0025.17O
ATOM1802N LEU A 2291.69331.112-17.1511.0024.24N
ATOM1803CA LEU A 2290.74432.168-17.4971.00 23.01C
[0282]ATOM1804CB LEU A 229-0.022 31.791 -18.7781.0023.14CΑ1ΌΜ1805CG LEU A229 0.775 31.867-20.0691.0022.56C
ATOM1806CDl LEU A229-0.064 31.269 -21.2471.0022.20C
ATOM1807CD2LEUA229 1.149 33.325 -20.2991.0021.22C
ATOM1808C LEU A 229-0.230 32.516-16.3921.00 22.06C
ATOM1809O LEU A 229-0.688 33.629-16.2851.0023.10O
ATOM1810N THRA 230-0.583 31.546-15.5871.00 22.44N
ATOM1811CA THRA 230-1.456 31.755-14.4451.0023.16C·ATOM1812CB THRA 230-2.054 30.399-13.9761.0023.62C
ATOM1813OGl THRA230-2.928 29.891 -14.9941.00 26.53O
ATOM1814CG2THRA230-2.852 30.552-12.7221.0024.80C
ATOM1815C THRA 230-0.681 32.438-13.3091.0022.80C
ATOM1816O THRA 230-1.205 33.305 -12.6691.0022.49O
ATOM1817N LEUA231 0.572 32.077-13.0931.00 23.76N
ATOM1818CA LEU A 231 1.366 32.678 -12.0011.0024.01C
ATOM1819CB LEU A 231 2.601 31.804-11.6721.0024.57C
ATOM1820CG LEU A 231 3.859 32.316-10.9151.0024.66C
ATOM1821CD1LEUA231 3.548 32.634 -9.4791.00 27.74C
ATOM1822CD2LEUA231 5.005 31.328-11.0061.00 23.01C
ATOM1823C LEUAZU 1.699 34.136-12.3061.0024.47C
ATOM1824O LEU A 231 1.311 35.031 -11.5741.00 25.47O
ATOM1825N TRPA 2322.350 34.387-13.4261.00 24.85N
ATOM1826CA TRPA 232 2.659 35.739-13.9021.00 24.80C
ATOM1827CB TRPA 232 3.282 35.612-15.2991.00 24.64C
ATOM1828CG TRPA 232 4.583 34.766-15.3341.00 24.26C
ATOM1829CDITRPA2325.437 34.525 -14.2881.00 22.67C
ATOM1830NEl TRPA 2326.504 33.765 -14.7051.0021.06N
ATOM1831CE2 TRPA 2326.386 33.529-16.0481.00 22.85C
ATOM1832CD2TRPA2325.180 34.146-16.4831.0024.70C
ATOM1833CE3TRPA2324.818 34.054-17.8491.00 23.81C
ATOM1834CZ3TRPA2325.644 33.335-18.7141.00 22.23C
ATOM1835CH2TRPA2326.860 32.749-18.2541.00 23.79C
ATOM1836CZ2 TRPA 2327.235 32.823 -16.9241.00 22.77C
ATOM1837C TRPA 2321.494 36.729-13.9911.0026.07C
ATOM1838O TRP A2321.686 37.963 -14.0341.00 25.93O
ATOM1839N TIIRA233 0.280 36.183 -14.0801.0026.37N
ATOM1840CA THRA 233-0.895 36.940 -14.3451.0026.03C
ATOM1841CB THRA 233-1.502 36.284 -15.6141.0026.67C
ATOM1842OGl THRA 233-1.652 37.231 -16.6911.00 25.34O
ATOM1843CG2THRA233-2.713 35.555-15.3261.0022.87C
ATOM1844C THRA 233-1.798 36.884-13.0501.0028.19C
ATOM1845O THRA233-2.998 37.221 -13.0701.00 26.97O
ATOM1846N SERA 234-1.192 36.459-11.9291.00 29.34N
ATOM1847CA SERA 234-1.897 36.153-10.6671.0031.26C
[0283]ATOM 1848CB SER A 234-1.18035.044 -9.856 1.0030.84CATOM 1849OG SERA 2340.02035.515 -9.254 1.0031.45O
ATOM 1850C SERA234-2.17237.388 -9.791 1.00 32.77C
ATOM 1851O SERA234-1.65838.493 -10.07/! 1.00 34.09O
ATOM 1852N ASPA 235-2.99337.220 -8.748 1.00 33.19N
ATOM 1853CA ASPA 235-3.21138.306 -7.800 1.00 34.49C
ATOM 1854CB ASPA 235-4.49238.078 -6.983 1.00 34.90C
ATOM1855CG ASPA 235-4.73539.174 -5.912 1.00 35.38C
ATOM1856ODl ASPA 235-4.94440.365 -6.246 1.00 33.44O
ATOM 1857OD2 ASPA 235-4.76438.809 -4.727 1.00 37.50O
ATOM 1858C ASPA 235-1.97938.520 -6.873 1.00 34.41C
ATOM1859O ASPA235-1.54239.639 -6.633 1.00 34.77O
ATOM1860OXTASPA 235-1.36637.601 -6.323 1.00 34.96OTER
ATOM1861N ALAB 1873.61730.766 -6.734 1.00 58.57N
ATOM1862CA ALAB 1873.842 29.292 -6.701 1.00 58.43C
ATOM1863CB ALAB 1873.54328.653 -8.072 1.00 57.93C
ATOM1864C ALAB 1875.28129.051 -6.287 1.00 58.33C
ATOM1865O ALAB 1875.56728.591 -5.163 1.00 58.23O
ATOM1866N ALAB 1886.17729.424 -7.196 1.00 58.29N
ATOM1867CA ALAB 1887.622 29.148 -7.119 1.00 58.31C
ATOM1868CB ALAB 1888.02128.257 -5.878 1.00 58.39C
ATOM1869C ALAB 1887.91128.435 -8.409 1.00 57.55C
ATOM1870O ALAB 1888.94628.639 -9.035 1.00 57.86O
ATOM1871N ARGB 1896.94827.621 -8.827 1.00 56.68N
ATOM1872CA ARGB 189 7.090 26.936-10.089 1.00 55.16C
ATOM1873CB ARGB1896.513 25.496 -10.069 1.00 55.96C
ATOM1874CG ARGB 189 5.029 25.215-10.319 1.00 56.20C
ATOM1875CD ARGB 189 5.013 23.729-10.760 1.00 59.82C
ATOM1876NE ARGB 189 3.758 22.964-10.727 1.0062.19N
ATOM1877CZ ARG B 1892.55523.376-11.143 1.00 62.92C
ATOM1878NHl ARG B 1892.36424.592-11.645 1.00 61.82N
ATOM1879NH2ARGB 1891.52322.543-11.043 1.00 63.64N
ATOM1880C ARGB 1896.73227.830-11.281 1.00 53.59C
ATOM1881O ARGB 1895.76227.589-12.030 1.00 53.93O
ATOM1882N VALB 1907.52728.898-11.412 1.0051.30N
ATOM1883CA VALB 1907.85729.398 -12.739 1.0049.18C
ATOM1884CB YALB 1908.50530.821 -12.767 1.0049.49C
ATOM1885CGl VALB 1909.03331.239-11.395 1.0050.36C
ATOM1886CG2VALB 1909.57330.929-13.894 1.0048.91C
ATOM1887C VALB 1908.77128.294-13.279 1.0047.14C
ATOM1888O VALB 1909.88728.086-12.808 1.0047.02O
ATOM1889N LEUB 1918.23627.533-14.221 1.00 44.50N ATOM1890CA LEUB 1918.82626.280-14.575 1.0041.21C
[0284]ATOM1891CB LEUB 1917.876 25.110-14.198 1.0041.42 CATOM1892CG LEUB 1916.598 24.659-14.914 1.00 40.73 C
ATOM1893CDl LEUB 1915.257 25.065 -14.232 1.00 38.71C
ATOM1894CD2 LEU B 1916.643 25.077-16.378 1.00 39.15C
ATOM1895C LEUB 1919.338 26.258-16.015 1.00 39.31C
ATOM1896O LEUB 1918.914 27.041 -16.849 1.00 38.64O
ATOM1897N SEPB 19210.284 25.353 -16.249 1.00 37.93N
ATOM1898CA SEPB 19211.007 25.123 -17.505 1.00 35.98 C
ATOM1899CB SEPB 19212.429 24.762-17.153 1.00 34.31C
ATOM1900OG SEPB 19213.240 25.873 -17.281 1.00 33.74 O
ATOM1901P SEPB 19214.615 25.617-16.524 1.00 23.53P
ATOM1902OlP SEPB 19214.121 25.320-15.082 1.00 33.09O
ATOM190302PSEPB 19215.271 27.010-16.129 1.00 27.42O
ATOM190403P SEPB19215.226 24.205-16.203 1.0026.84O
ATOM1905C SEPB 19210.539 23.883-18.207 1.00 35.09C
ATOM1906O SEPB 1929.856 23.062-17.629 1.00 34.32O
ATOM1907N ALAB 19311.025 23.696-19.425 1.00 35.14N
ATOM1908CA ALAB 19310.783 22.452-20.125 1.00 35.92 C
ATOM1909CB ALAB 19311.122 22.557 -21.612 1.00 35.38 C
ATOM1910C ALAB 19311.596 21.350-19.453 1.00 35.79C
ATOM1911O ALAB 19312.706 21.590-18.971 1.00 35.68O
ATOM1912N PROB 19411.035 20.129-19.434 1.00 35.61N
ATOM1913CA PRO B 19411.892 18.999-19.123 1.00 35.77 C
ATOM1914CB PROB19410.897 17.854-18.958 1.00 35.67 C
ATOM1915CG PROB 1949.648 18.280-19.756 1.00 35.83 C
ATOM1916CD PROB 1949.653 19.752-19.810 1.00 35.53 C
ATOM1917C PROB 19412.717 18.935 -20.435 1.00 35.55C
ATOM1918O PROB 19412.460 19.731 -21.325 1.00 37.29O
ATOM1919N PHEB 19513.699 18.093 -20.632 1.00 34.52N
ATOM1920CA PHEB 19514.445 18.264-21.917 1.00 32.86 C
ATOM1921CB PHEB 19513.675 17.605 -23.084 1.0032.39 C
ATOM1922CG PHEB 19512.627 18.485 -23.721 1.00 31.99 C
ATOM1923CDl PHEB 19512.978 19.430 -24.697 1.00 29.58C
ATOM1924CEl PHE B 19511.992 20.219-25.328 1.0031.94C
ATOM1925CZ PHEB19510.637 20.044 -24.988 1.0029.92 C
ATOM1926CE2PHEB 19510.279 19.114-24.014 1.0031.11C
ATOM1927CD2PHEB 19511.264 18.315-23.403 1.0031.68C
ATOM1928C PHEB 19514.907 19.683 -22.373 1.00 32.65C
ATOM1929O PHEB 19515.853 19.693 -23.163 1.00 33.15O
ATOM1930OXTPHEB 19514.415 20.825 -22.127 1.00 30.98 OTER
ATOM1931N METC I40.504 29.895 9.195 1.00 35.84 N
ATOM1932CA METC I 39.040 29.750 9.525 1.00 35.81 C
ATOM1933CB METC I 38.316 28.824 8.537 1.00 35.26 C
[0285]ATOM1934CG METCI37.510 29.5327.4701.00 35.46CATOM1935SD METCI36.533 28.3586.4711.00 35.98S
ATOM1936CE METCI34.916 28.6117.1891.00 33.95C
ATOM1937C METCI38.800 29.24410.9331.00 34.93C
ATOM1938O METCI39.332 28.21811.3401.00 34.23O
ATOM1939N SERC237.987 29.98711.6591.0035.76N
ATOM1940CA SERC237.667 29.68613.0441.00 37.16C
ATOM1941CB SERC237.218 30.96513.7421.00 36.68C·ATOM1942OG SERC235.879 31.29113.4041.00 38.43O
ATOM1943C SERC236.569 28.61613.1541.0038.06C
ATOM1944O SERC235.782 28.40412.1991.00 38.93O
ATOM1945N ARGC336.519 27.96114.3191.00 38.55N
ATOM1946CA ARGC335.518 26.93414.637 1.00 39.39C
ATOM1947CB ARGC335.803 26.31016.0301.00 39.93C
ATOM1948CG ARGC334.617 25.78716.848 1.0041.14C
ATOM1949CD ARGC334.937 24.46817.550 1.0042.02C
ATOM1950NE ARGC333.987 24.13918.6211.00 42.54N
ATOM1951CZ ARGC334.067 23.06219.4161.00 41.89C
ATOM1952NIilARGC335.031 22.16319.2721.0042.06N
ATOM1953NH2ARGC333.168 22.88120.3721.00 40.86N
ATOM1954C ARGC334.080 27.44314.4391.00 39.32C
ATOM1955O ARGC333.233 26.70513.9041.00 39.77O
ATOM1956N GLUC433.817 28.70414.8001.00 39.02N
ATOM1957CA GLUC432.504 29.32914.5021.00 38.88C
ATOM1958CB GLUC432.204 30.61015.3271.00 40.02C
ATOM1959CG GLUC433.403 31.19116.1591.00 44.44C
ATOM1960CD GLUC433.568 32.73216.0551.0048.30C
ATOM1961OEl GLUC434.444 33.20315.2701.00 50.41O
ATOM1962OE2GLUC432.821 33.45916.7531.0049.11O
ATOM1963C GLUC432.234 29.54512.9971.0037.85C
ATOM1964O GLUC431.077 29.42912.5661.0036.94O
ATOM1965N GLUC533.280 29.82512.2111.00 36.36N
ATOM1966CA GLUC533.124 30.01110.7561.00 35.71C
ATOM1967CB GLUC534.319 30.75710.1511.00 35.83C
ATOM1968CG GLUC534.448 32.23710.6061.00 35.97C
ATOM1969CD GLUC535.674 32.96410.0471.00 35.62C
ATOM1970OEl GLU C536.794 32.44010.1611.0031.93O
ATOM1971OE2GLUC535.510 34.0829.5031.00 37.36O
ATOM1972C GLUC532.865 28.68210.0241.0035.67C
ATOM1973O GLUC531.988 28.6149.1411.00 35.91O
ATOM1974N ASNC633.609 27.63910.4131.0035.02N
ATOM1975CA ASNC633.452 26.2659.9101.0034.60C
ATOM1976CB ASNC634.471 25.32710.5361.00 34.44C
ATOM1977CG ASNC635.835 25.4469.9271.0034.28C
[0286]ATOM1978ODl ASN C6 36.00825.2508.7281.0029.95OATOM1979ND2ASNC6 36.83825.75510.7641.0035.23N
ATOM1980C ASNC6 32.07225.69110.1871.0035.05C
ATOM1981O ASNC6 31.44325.0699.3071.0034.29O
ATOM1982N VALC7 31.61525.89011.4191.00 34.72N
ATOM1983CA VALC7 30.28125.45711.8061.00 34.49C
ATOM1984CB VALC7 30.05125.61413.3231.00 34.80C
ATOM1985CGl VALC7 28.54425.67713.6611.00 32.67C·ATOM1986CG2VALC7 30.75824.47114.0811.00 33.29C
ATOM1987C VALC7 29.22026.21411.0041.00 34.82C
ATOM1988O VALC7 28.25325.60810.4941.00 33.97O
ATOM1989N TYRC8 29.41627.52910.9051.0033.88N
ATOM1990CA TYRC8 28.55628.38310.1051.00 33.76 C
ATOM1991CB TYRC8 29.02629.84410.1831.00 33.61C
ATOM1992CG TYRC8 28.17430.752 9.3541.00 33.12C
ATOM1993CDl TYRC8 28.49931.0128.0211.00 32.49C
ATOM1994CEl TYRC8 27.68431.8337.2271.00 33.73C
ATOM1995CZ TYRC8 26.54132.4087.7971.00 32.83C
ATOM1996Oil TYRC8 25.75233.223 7.0481.00 33.70O
ATOM1997CE2TYRC8 26.19932.1689.1271.00 32.93C
ATOM1998CD2TYRC8 27.02031.3419.8991.0031.93C
ATOM1999C TYRC8 28.46927.8868.6371.00 33.16C
ATOM2000O TYRC8 27.37527.7208.0831.00 34.05O
ATOM2001N METC9 29.61927.6308.0321.00 32.13N
ATOM2002CA METC 9 29.68927.144 6.6661.0031.47C
ATOM2003CB METC9 31.12127.226 6.1531.00 32.29C
ATOM2004CG METC 9 31.65128.653 5.9291.00 33.72C
ATOM2005SD METC9 30.73329.5614.6721.00 38.98S
ATOM2006CE METC9 31.50128.8743.2171.00 34.80C
ATOM2007C METC9 29.18225.7206.4621.0031.35C
ATOM2008O METC9 28.77425.3685.3351.0031.78O
ATOM2009N ALAC10 29.24524.8877.5101.00 29.61N
ATOM2010CA ALAC10 28.71923.537 7.4421.0029.12C
ATOM2011CB ALAC10 29.13322.698 8.6701.0028.28C
ATOM2012C ALAC10 27.20023.6077.3141.00 28.85C
ATOM2013O ALAC10 26.60422.7516.6711.0028.09O
ATOM2014N LYSC11 26.60524.6257.9471.0028.82N
ATOM2015CA LYSC11 25.18824.9197.8781.0030.52C
ATOM2016CB LYSC11 24.78525.9118.9601.00 30.77C
ATOM2017CG LYSC11 24.63625.28210.3621.00 32.51C
ATOM2018CD LYSC11 24.22726.35011.3711.00 35.18C
ATOM2019CE LYSC11 24.46225.91212.8031.00 36.64C
ATOM2020NZ LYSC11 25.06827.05413.5701.00 38.19N
ATOM2021C LYSC11 24.76725.4576.5211.00 30.72C
[0287]ATOM2022O LYSC1123.65425.1986.0701.00 30.40OATOM2023N LEUC1225.66726.2055.8911.0031.40N
ATOM2024CA LEUC1225.47426.7374.5481.00 31.58C
ATOM2025CB LEUC1226.59527.7324.2061.00 31.98C
ATOM2026CG LEUC1226.28329.0743.5131.00 32.55C
ATOM2027CDl LEU C1227.47829.5062.6391.0029.38C
ATOM2028CD2LEUC1224.96329.0422.7221.00 30.76C
ATOM2029C LEUC1225.51425.5803.5541.0031.43C
ATOM2030O LEUC1224.61325.4202.7391.0031.19O
ATOM2031N ALAC1326.57324.7833.6291.00 30.70N
ATOM2032CA ALAC1326.71123.5802.8101.00 30.42C
ATOM2033CB ALAC1328.05522.9063.0901.0029.97C
ATOM2034C ALAC1325.54722.5982.9841.00 30.60C
ATOM2035O ALAC1325.17421.8902.0401.00 31.51O
ATOM2036N GLUC1424.97222.5424.1781.0029.86N
ATOM2037CA GLUC1423.83021.6614.4161.00 29.78C
ATOM2038CB GLUC1423.51521.5435.9081.0029.60C
ATOM2039CG GLUC1422.43620.5036.2281.0030.86 C
ATOM2040CD GLUC1421.91120.6047.6461.00 30.71C
ATOM2041OEl GLUC1422.05521.6818.2391.0031.76O
ATOM2042OE2GLUC1421.33219.6228.1581.0031.76O
ATOM2043C GLUC1422.61122.1693.6821.00 28.68C
ATOM2044O GLUC1421.90421.4223.0501.0028.25O
ATOM2045N GLNC1522.36323.4573.8251.00 28.19N
ATOM2046CA GLNC1521.33324.1123.0911.0028.39C
ATOM2047CB GLNC1521.19425.5363.5781.0028.28C
ATOM2048CG GLNC1520.48025.5214.8781.00 32.51C
ATOM2049CD GLNC1519.86826.8195.1771.0040.06C
ATOM2050OEl GLN C1518.65226.9845.0301.00 43.41O
ATOM2051NE2 GLN C1520.69627.7905.5801.00 41.48N
ATOM2052C GLNC1521.47423.9971.5631.0027.36C
ATOM2053O GLNC1520.49023.7150.8891.00 26.29O
ATOM2054N ALAC1622.69024.2221.0581.0025.89N
ATOM2055CA ALAC1623.06424.012-0.3551.00 25.54C
ATOM2056CB ALAC1624.48224.511-0.6141.00 23.64C
ATOM2057C ALAC1622.96322.559-0.8091.00 25.47C
ATOM2058O ALAC1623.02222.281-2.0271.00 26.07O
ATOM2059N GLUC1722.88321.6390.1641.0024.68N
ATOM2060CA GLUC1722.82620.212-0.0791.0025.27C
ATOM2061CB GLUC1721.58719.825-0.9321.00 24.96C
ATOM2062CG GLUC1720.25420.178-0.2791.0022.70C
ATOM2063CD GLUC1719.09619.343-0.8591.0028.39C
ATOM2064OEl GLU C1719.01319.190-2.0971.0031.46O
ATOM2065OE2GLUC1718.27318.809-0.0811.00 33.36O
[0288]ATOM2066C GLUC 17 24.11919.705-0.6991.00 25.65CATOM2067O GLUC 17 24.11918.832-1.5661.0025.05O
ATOM2068N ARGC 18 25.23420.238-0.1921.0026.36N
ATOM2069CA ARGC 18 26.54919.887 -0.6661.00 26.11C
ATOM2070CB ARGC 18 27.27121.144-1.1021.00 27.14C
ATOM2071CG ARGC 18 26.77421.734-2.3981.00 26.43C
ATOM2072CD ARGC 18 27.74722.827-2.7671.00 28.62 C
ATOM2073NE ARGC 18 27.81322.778-4.1891.00 36.47N
ATOM2074CZ ARGC 18 28.90922.726-4.9181.00 39.89C
ATOM2075NHl ARG C 18 28.75022.648-6.2241.00 44.72N
ATOM2076NH2ARGC 18 30.12422.818-4.3861.00 38.78N
ATOM2077C ARGC 18 27.28419.2590.4811.0026.53C
ATOM2078O ARGC 18 28.04619.9411.2281.00 26.70O
ATOM2079N TYRC 19 27.04517.9640.6501.0025.71N
ATOM2080CA TYRC 19 27.35817.3181.9241.0026.19C
ATOM2081CB TYRC 19 26.43316.1382.1771.0025.46C
ATOM2082CG TYRC 19 24.98716.5092.2571.00 25.72C
ATOM2083CDl TYRC 19 24.48317.1723.3921.0026.82C
ATOM2084CEl TYRC 19 23.12117.5223.4921.0026.87C
ATOM2085CZ TYRC 19 22.25317.1962.4301.00 25.57C
ATOM2086OH TYRC 19 20.93317.5422.5571.00 26.00O
ATOM2087CE2TYRC 19 22.72716.5601.2981.0024.82C
ATOM2088CD2TYRC 19 24.10816.1961.2151.0025.14C
ATOM2089C TYRC 19 28.79416.8782.0621.00 26.21C
ATOM2090O TYRC 19 29.26216.7343.1851.00 26.07O
ATOM2091N GLUC 20 29.46816.6330.9351.0026.16N
ATOM2092CA GLUC 20 30.92616.4130.9201.00 26.63C
ATOM2093CB GLUC 20 31.43216.158-0.4981.00 26.69C
ATOM2094CG GLUC 20 31.06814.807-1.0801.0028.77C
ATOM2095CD GLUC 20 29.69714.770-1.7971.00 32.68C
ATOM2096OEl GLUC 20 28.86515.706-1.6861.00 34.39O
ATOM2097OE2GLUC 20 29.45413.766-2.4831.00 33.19O
ATOM2098C GLUC 20 31.69617.5981.5101.0025.98C
ATOM2099O GLUC 20 32.65917.4272.2361.0026.77O
ATOM2100N GLUC 21 31.26318.7921.1741.0026.02N
ATOM2101CA GLUC 21 31.82820.0011.7191.00 26.69C
ATOM2102CB GLUC 21 31.42821.1900.8521.0026.25C
ATOM2103CG GLUC 21 32.06621.089-0.5181.00 27.03C
ATOM2104CD GLUC 21 31.55722.125-1.4991.0025.91C
ATOM2105OEl GLUC 21 32.11022.177-2.6101.0029.30O
ATOM2106OE2GLUC 21 30.61322.877-1.1781.0025.88O
ATOM2107C GLUC 21 31.40520.2013.1811.00 27.28C
ATOM2108O GLUC 21 32.19520.7404.0081.0026.42O
ATOM2109N METC 22 30.18519.7673.4981.0026.26N
[0289]ATOM2110CA METC 22 29.70519.849 4.862 1.00 27.66CATOM2111CB METC 22 28.24119.4744.9471.00 26.89C
ATOM2112CG METC 22 27.64819.559 6.337 1.0026.98C
ATOM2113SD METC 22 25.97718.8736.2931.0029.55S
ATOM2114CE METC 22 25.42919.2657.9641.0021.87C
ATOM2115C METC 22 30.54318.9855.8071.00 27.74C
ATOM2116O METC 22 30.92519.4406.8991.00 27.78O
ATOM2117N VALC 23 30.82117.7525.3631.00 28.69N·ATOM2118CA VALC 23 31.75116.8086.0101.00 29.08C
ATOM2119CB VALC 23 31.89515.5355.1561.0028.91C
ATOM2120CGl VALC 23 33.10514.6905.5461.00 28.09C
ATOM2121CG2YALC 23 30.59714.6925.1841.0028.34C
ATOM2122C VALC 23 33.13417.4726.2901.00 30.59C
ATOM2123O VALC 23 33.66517.3647.4211.00 30.41O
ATOM2124N GLUC 24 33.68018.1385.2591.0031.32N
ATOM2125CA GLUC 24 34.97918.830 5.2991.00 32.30C
ATOM2126CB GLUC 24 35.30019.4913.9421.00 32.20C
ATOM2127CG GLUC 24 35.62918.5322.8021.0031.91C
ATOM2128CD GLUC 24 36.15419.231 1.5211.0032.46C
ATOM2129OEl GLUC 24 35.62620.2881.0931.00 34.24O
ATOM2130OE2GLUC 24 37.13118.7270.9381.00 33.70O
ATOM2131C GLUC 24 35.00219.8826.3971.00 32.71C
ATOM2132O GLUC 24 35.91719.8847.2201.00 34.27O
ATOM2133N TYRC 25 33.99120.7536.4061.00 33.16N
ATOM2134CA TYRC 25 33.82721.8047.4141.00 33.91C
ATOM2135CB TYRC 25 32.57622.6607.1521.00 34.27C
ATOM2136CG TYRC 25 32.68423.6065.9661.00 35.14C
ATOM2137CDl TYRC 25 33.72324.5395.8861.00 35.15C
ATOM2138CEl TYRC 25 33.83725.3974.7961.00 36.11C
ATOM2139CZ TYRC 25 32.89825.3573.7631.00 37.12C
ATOM2140OH TYRC 25 33.03326.2262.6951.00 35.75O
ATOM2141CE2TYRC 25 31.82824.4403.8091.00 37.40C
ATOM2142CD2TYRC 25 31.73123.5734.9191.00 37.09C
ATOM2143C TYRC 25 33.76921.2638.8231.00 34.44C
ATOM2144O TYRC 25 34.50721.7249.7041.00 33.81O
ATOM2145N METC 26 32.87820.2929.0291.00 35.27N
ATOM2146CA METC 26 32.70219.62510.336 1.0036.13C
ATOM2147CB METC 26 31.44718.75710.345 1.00 34.94C
ATOM2148CG METC 26 30.18019.55310.407 1.00 34.91C
ATOM2149SD METC 26 30.20520.93211.5961.00 35.60S
ATOM2150CE METC 26 30.37820.00313.1451.00 34.54C
ATOM2151C METC 26 33.90518.80210.8341.00 36.86C
ATOM2152O METC 26 34.09618.66312.0311.00 36.07O
ATOM2153N GLUC 27 34.66718.2199.9121.00 38.95N
[0290]ATOM2154CA GLUC 27 35.848 17.44310.2611.00 40.40 CATOM2155CB GLUC 27 36.349 16.6669.0351.0040.60 C
ATOM2156CG GLUC 27 37.292 15.5049.3701.0043.24 C
ATOM2157CD GLUC 27 36.889 14.1838.7341.0045.72 C
ATOM2158OEl GLUC 2735.92313.5239.2261.0043.66O
ATOM2159OE2GLUC 2737.57113.7897.7571.0048.30O
ATOM2160C GLUC 2736.93718.35610.8611.0041.35C
ATOM2161O GLUC 2737.64617.96111.8001.00 40.60O
ATOM2162N LYSC 2837.03219.57510.3201.0042.86N
ATOM2163CA LYSC 2837.90820.65310.8521.0044.36C
ATOM2164CB LYSC 2837.86521.8879.9431.0043.95C
ATOM2165CG LYSC 2839.06822.0429.0641.0045.87C
ATOM2166CD LYSC 2838.67722.5217.6761.0048.65C
ATOM2167CE LYSC 2838.12823.9307.6821.00 49.43C
ATOM2168NZ LYSC 2837.24024.1786.5021.00 51.67N
ATOM2169C LYSC 2837.46821.07612.2401.00 45.08C
ATOM2170O LYSC 2838.29721.33113.1151.00 45.05O
ATOM2171N VALC 2936.15321.18012.4231.0046.10N
ATOM2172CA VALC 2935.57721.38813.7401.00 47.08 C
ATOM2173CB VALC 2934.05221.55413.6931.00 46.94C
ATOM2174CGl VALC 2933.48221.66015.1031.0046.66C
ATOM2175CG2VALC 2933.68722.77012.8891.0045.32C
ATOM2176C VALC 2935.96220.22614.6451.00 48.58C
ATOM2177O VALC 2936.40420.44915.7651.00 49.16O
ATOM2178N ALAC 3035.84518.99514.1511.0049.89N
ATOM2179CA ALAC 30 36.023 17.81614.9941.0051.33 C
ATOM2180CB ALAC 3035.449 16.58214.3351.0051.69 C
ATOM2181C ALAC 3037.46617.58415.3991.00 52.86C
ATOM2182O ALAC 3037.72617.07216.4861.00 53.22O
ATOM2183N LYSC 3138.40017.97714.5331.00 54.67N
ATOM2184CA LYSC 3139.82617.91714.8371.00 56.04C
ATOM2185CB LYSC 3140.63117.90813.5411.00 55.88C
ATOM2186CG LYSC 3140.77516.51012.8971.00 55.10C
ATOM2187CD LYSC 3141.79216.52811.7401.00 55.91C
ATOM2188CE LYSC 3141.79915.23910.9301.0056.15C
ATOM2189NZ LYSC 3140.54715.04610.1191.00 56.84N
ATOM2190C LYSC 3140.28219.04215.7871.00 57.73C
ATOM2191O LYSC 3141.47319.20416.0511.00 57.67O
ATOM2192N THRC 3239.30119.77016.3251.00 59.96N
ATOM2193CA THRC 32 39.48020.96217.1711.0061.90 C
ATOM2194CB TIIRC 3238.58622.11916.6501.00 61.84C
ATOM2195OGl THRC 3239.32122.88915.6861.0061.65O
ATOM2196CG2THRC 3238.08823.02517.7741.0061.92C
ATOM2197C THRC 3239.19320.63318.6491.00 63.43C
[0291]ATOM2198O THRC3239.46121.43319.5681.00 64.14OATOM2199N VALC3338.62619.44718.8591.00 64.75N
ATOM2200CA VALC3338.74518.73020.1231.00 65.58C
ATOM2201CB VALC3338.14917.26819.9981.00 65.65C
ATOM2202CGl VAL C3338.51916.41321.2081.00 65.70C
ATOM2203CG2VALC3336.61817.28019.7521.00 64.54C
ATOM2204C VALC3340.25518.68220.4511.00 66.16C
ATOM2205O VALC3340.98717.81319.9441.00 66.52O
ATOM2206N ASPC3440.73719.65321.2271.00 66.70N
ATOM2207CA ASPC3442.04519.51121.8491.00 67.06C
ATOM2208CB ASPC3442.60420.85922.3361.00 67.52C
ATOM2209CG ASPC3444.14020.82622.5901.00 68.45C
ATOM2210ODl ASP C3444.84819.91222.0871.00 69.16O
ATOM2211OD2ASPC3444.63821.73723.2981.00 67.97O
ATOM2212C ASPC3441.78218.53022.9981.00 67.02C
ATOM2213O ASPC3441.95117.31222.8311.00 67.55O
ATOM2214N VALC3541.32719.04824.1391.00 66.29N
ATOM2215CA VALC3540.80418.19325.2091.00 65.38C
ATOM2216CB VALC3541.39018.56526.6241.00 65.56C
ATOM2217CGl VALC3541.59317.30327.4841.00 65.31C
ATOM2218CG2VALC3542.72919.34126.5011.00 65.68C
ATOM2219C VALC3539.24618.23725.1641.00 64.39C
ATOM2220O YALC3538.57817.22725.4181.00 64.06O
ATOM2221N , ALAC3638.70419.41024.7991.00 62.95N
ATOM2222CA ALAC3637.25019.69724.6981.00 61.35C
ATOM2223CB ALAC3637.02321.20024.3411.00 61.57C
ATOM2224C ALAC3636.41818.78623.7471.00 60.01C
ATOM2225O ALAC3636.94917.88923.0611.00 60.04O
ATOM2226N GLUC3735.10819.03423.7191.00 57.30N
ATOM2227CA GLUC37 34.16118.16223.021 1.00 54.93C
ATOM2228CB GLUC3733.44417.25924.0241.00 54.91C
ATOM2229CG GLUC3734.40516.46124.885 1.00 55.33C
ATOM2230CD GLUC37 33.75515.87526.1181.00 56.41C
ATOM2231OEl GLU C3732.95814.91325.9721.00 57.69O
ATOM2232OE2GLUC3734.05516.37327.2301.00 54.99O
ATOM2233C GLUC3733.14618.96022.2151.00 52.66C
ATOM2234O GLUC3732.70920.04922.6281.0051.94O
ATOM2235N LEUC3832.79218.41121.0551.00 50.32N
ATOM2236CA LEUC3831.77819.00820.1971.00 47.57C
ATOM2237CB LEUC3831.46918.09419.0121.0047.25C
ATOM2238CG LEUC3832.60017.82918.0161.00 45.73C
ATOM2239CDl LEU C3832.04517.14916.7561.0043.36C
ATOM2240CD2LEUC3833.34319.11717.6591.0042.80C
ATOM2241C LEUC3830.52019.27021.0081.0046.30C
[0292]ATOM2242O LEUC3830.14818.45221.8531.00 46.09OATOM2243N THRC3929.87820.41420.7911.00 44.41N
ATOM2244CA THRC3928.59620.63821.4251.0043.20C
ATOM2245CB THRC3928.11022.09521.2931.00 43.53C ATOM2246OGl THRC3927.56322.29719.9851.0043.86O
ATOM2247CG2THRC3929.24723.11421.5881.00 42.39C
ATOM2248C THRC3927.57019.64920.8271.00 42.34C
ATOM2249O THRC3927.90518.83919.9601.00 42.27O
ATOM2250N VALC4026.33119.68721.2941.0041.53N
ATOM2251CA VALC4025.31918.80320.7231.00 40.70C
ATOM2252CB VALC4024.02518.77721.5851.00 40.74C
ATOM2253CGl VAL C4022.87718.08320.8571.0040.68C
ATOM2254CG2VALC4024.29418.09122.9491.0040.04C
ATOM2255C VALC4025.08719.20619.2401.00 40.46C
ATOM2256O VALC4025.14318.36018.3521.00 40.26O
ATOM2257N GLUC4124.88220.50018.9921.00 39.27N
ATOM2258CA GLUC4124.72221.02717.6461.00 38.93C
ATOM2259CB GLUC4124.75022.55017.6831.00 39.18C
ATOM2260CG GLUC4124.38923.23616.3381.0040.43C
ATOM2261CD GLUC4124.83624.69616.3031.00 39.86C
ATOM2262OEl GLUC4123.98225.57216.0851.0040.00O
ATOM2263OE2GLUC4126.04024.95916.5141.0042.03O
ATOM2264C GLU C4125.78920.53816.6721.00 38.20C
ATOM2265O GLUC4125.47919.96915.6101.00 37.70O
ATOM2266N GLUC4227.04320.77817.0401.00 36.77N
ATOM2267CA GLUC4228.17720.45316.2191.00 36.31C
ATOM2268CB GLUC4229.45220.89716.9211.00 36.29C
ATOM2269CG GLUC4229.44922.34417.2581.00 37.68C
ATOM2270CD GLUC4230.74722.75417.8911.00 38.90C
ATOM2271OEl GLUC4231.31421.94618.6541.00 35.64O
ATOM2272OE2GLUC4231.19923.87417.6011.0041.07O
ATOM2273C GLUC4228.27718.97715.9881.00 35.81C
ATOM2274O GLUC4228.56618.52714.8741.00 36.16O
ATOM2275N ARGC4328.08018.22417.0701.00 35.37N
ATOM2276CA ARGC4328.13116.77217.0241.00 34.95C
ATOM2277CB ARGC4328.00816.20018.4391.00 35.24C
ATOM2278CG ARGC4327.83214.67318.5071.00 36.22C
ATOM2279CD ARGC4326.42914.32218.8761.0037.13C
ATOM2280NE ARGC4326.24514.23620.3141.00 35.78N
ATOM2281CZ ARGC4325.06114.28320.9201.00 33.24C
ATOM2282NHl ARG C4323.93514.42620.2231.00 30.48N
ATOM2283NH2ARGC4325.02014.17522.2351.0029.54N
ATOM2284C ARGC4327.03416.21516.0991.00 33.63C
ATOM2285O ARGC4327.27015.27915.3731.00 33.63O
[0293]ATOM2286N ASNC4425.85216.80716.1391.00 33.33NATOM2287CA ASNC 44 24.735 16.42115.2511.00 33.40C
ATOM2288CB ASNC 44 23.44917.06515.7531.00 33.56C
ATOM2289CG ASNC 44 22.885 16.38316.998 1.0033.83C
ATOM2290ODl ASN C4423.32115.29417.3691.00 32.23O
ATOM2291ND2ASNC4421.88717.02417.6351.00 32.20N
ATOM2292C ASNC4424.92816.80213.7651.00 32.83C
ATOM2293O ASNC4424.32516.20512.8581.00 32.86O·ATOM2294N LEUC4525.75117.81813.5321.0031.75N
ATOM2295CA LEUC4525.97418.35512.1961.00 30.80C
ATOM2296CB LEUC4526.54519.76512.3021.00 30.74C
ATOM2297CG LEUC4525.75821.02311.9601.0031.82C
ATOM2298CDl LEU C4524.23720.89012.1301.00 32.53C
ATOM2299CD2LEUC4526.35822.21412.7501.0029.96C
ATOM2300C LEUC4526.94817.47211.4611.0029.74C
ATOM2301O LEUC4526.90217.33210.2321.0029.29O
ATOM2302N LEU C4627.86016.91412.2431.0028.56N
ATOM2303CA LEUC4628.84015.96011.7881.00 27.64C
ATOM2304CB LEUC4629.88215.73112.8681.00 27.22C
ATOM2305CG LEUC4630.81414.56612.5501.00 27.57C
ATOM2306CDl LEU C4631.64914.84711.2941.00 30.31C
ATOM2307CD2LEUC4631.69214.22713.7271.00 31.01C
ATOM2308C LEUC4628.17314.61511.4631.0027.23C
ATOM2309O LEUC4628.60813.91310.5481.00 26.52O
ATOM2310N SERC4727.17014.24112.2481.0026.79N
ATOM2311CA SERC4726.47512.99711.9991.0027.26C
ATOM2312CB SERC4725.53012.65013.1501.0027.76C
ATOM2313OG SERC4724.90211.39512.9311.00 28.49O
ATOM2314C SERC4725.73913.15910.6751.0026.56C
ATOM2315O SERC4726.03412.4609.7471.00 27.97〇
ATOM2316N VALC4824.86414.15610.5871.00 26.42N
ATOM2317CA VALC4824.06314.4789.3931.0025.21C
ATOM2318CB VALC4823.26615.8129.6101.0025.21C
ATOM2319CGl VALC4822.64716.3538.3181.0027.20C
ATOM2320CG2VALC4822.19415.63110.6611.0023.76C
ATOM2321C VALC4824.87714.5628.1041.0024.91C
ATOM2322O VALC4824.41714.1187.0521.0023.63O
ATOM2323N ALAC4926.06715.1698.1811.0023.96N
ATOM2324CA ALAC4926.95115.3597.0371.0023.43C
ATOM2325CB ALAC4928.21916.1597.4671.00 24.62C
ATOM2326C ALAC4927.35014.0466.4081.0024.12C
ATOM2327O ALAC4927.17213.8415.2021.00 23.47O
ATOM2328N TYRC5027.90713.1637.2531.0024.35N
ATOM2329CA TYRC5028.36911.8426.8751.00 24.08C
[0294]ATOM2330CB TYRC 50 29.141 11.1888.008 1.0024.58CATOM2331CG TYRC 50 30.613 11.3917.873 1.0026.25C
ATOM2332CDl TYRC 50 31.32410.7656.857 1.0024.82C
ATOM2333CEl TYRC 50 32.67910.9686.712 1.0027.71C
ATOM2334CZ TYRC 50 33.349 11.8237.603 1.0026.98C
ATOM2335OH TYRC 50 34.684 12.017 7.474 1.00 29.03O
ATOM2336CE2TYRC 50 32.68112.4628.617 1.00 26.93C
ATOM2337CD2TYRC 50 31.28912.2378.750 1.0026.28C
ATOM2338C TYRC 50 27.24510.8996.467 1.00 23.49C
ATOM2339O TYRC 50 27.47010.0325.633 1.0022.17O·
ATOM2340N LYSC 51 26.08911.0697.091 1.00 23.17N
ATOM2341CA LYSC 51 24.93410.2146.861 1.0025.02C
ATOM2342CB LYSC 51 23.82410.5427.866 1.0025.28C
ATOM2343CG LYSC 51 22.569 9.7047.655 1.00 27.81C
ATOM2344CD LYSC 51 21.753 9.5758.937 1.00 33.74C
ATOM2345CE LYSC 51 21.352 8.1019.216 1.00 36.39C
ATOM2346NZ LYSC 51 20.030 7.6898.550 1.0037.17N
ATOM2347C LYSC 51 24.40110.4465.493 1.00 24.16C
ATOM2348O LYSC 51 23.8369.5504.879 1.00 25.71O
ATOM2349N ASNC 52 24.52311.6915.054 1.0023.97N
ATOM2350CA ASNC 52 24.066 12.0943.754 1.0023.69C
ATOM2351CB ASNC 52 23.738 13.5723.753 1.0023.15C
ATOM2352CG ASNC 52 22.366 13.8304.277 1.0023.14C
ATOM2353ODl ASN C 52 22.16313.9095.465 1.00 23.65O
ATOM2354ND2ASNC 52 21.38713.9183.379 1.00 26.74N
ATOM2355C ASNC 52 25.06611.7222.680 1.0023.76C
ATOM2356O ASNC 52 24.70511.2031.637 1.0021.65O
ATOM2357N VALC 53 26.33911.9672.956 1.00 23.72N
ATOM2358CA VALC 53 27.41211.4992.070 1.0023.77C
ATOM2359CB VALC 53 28.80412.0172.578 1.0023.82C
ATOM2360CGl VAL C 53 29.93711.4511.791 1.0024.05C
ATOM2361CG2VALC 53 28.84013.4812.455 1.0021.64C
ATOM2362C VALC 53 27.3959.9801.898 1.00 24.37C
ATOM2363O VALC 53 27.445 9.4910.753 1.0025.72O
ATOM2364N ILEC 54 27.3199.2213.004 1.0023.02N
ATOM2365CA ILEC 54 27.2937.7442.906 1.00 22.26C
ATOM2366CB ILEC 54 27.5827.0424.267 1.00 22.06C
ATOM2367CGl ILE C 54 28.2065.6584.091 1.0023.25C
ATOM2368CDl ILE C 54 29.4175.5843.242 1.0025.66C
ATOM2369CG2ILEC 54 26.3056.8485.152 1.0022.47C
ATOM2370C ILEC 54 25.9537.2162.279 1.00 22.57C
ATOM2371O ILEC 54 25.9726.2691.489 1.0020.94O
ATOM2372N GLYC 55 24.852 7.8522.681 1.0022.20N
ATOM2373CA GLYC 55 23.499 7.4792.345 1.0024.76C
[0295]ATOM2374CGLYC 55 23.3137.4820.8571.00 25.40CATOM2375OGLYC 55 22.8546.5100.3271.0026.80O
ATOM2376NALAC 56 23.6658.5880.2011.00 26.25N
ATOM2377CA ALAC 56 23.7488.653-1.2511.00 27.18C
ATOM2378CBALAC 56 24.4699.931-1.6851.00 27.53C
ATOM2379CALAC 56 24.4067.431-1.8761.00 26.90C
ATOM2380OALAC 56 23.8416.821-2.7841.00 27.46O
ATOM2381NARGC 57 25.6017.075-1.4101.00 27.29N·
ATOM2382CAARGC 57 26.320 5.889 -1.956 1.0027.13C
ATOM2383CBARGC 57 27.8145.890-1.6081.0026.98C
ATOM2384CGARGC 57 28.6616.773-2.508 1.0028.70C
ATOM2385CDARGC 57 28.4578.217 -2.127 1.00 29.74C
ATOM2386NEARGC 57 29.3319.156-2.8081.0028.85N
ATOM2387CZARGC 57 29.24410.468-2.6471.00 28.56C
ATOM2388NHl ARG C 57 30.06511.262-3.3041.00 27.09N
ATOM2389NH2ARGC 57 28.32710.974-1.8341.0028.48N
ATOM2390CARGC 57 25.7174.512-1.6081.00 26.65C
ATOM2391OARGC 57 25.9413.553-2.3491.0026.08O
ATOM2392NARGC 58 25.0114.398-0.4751.0025.71N
ATOM2393CAARGC 58 24.2993.156-0.1771.00 25.35C
ATOM2394CBARGC 58 23.8963.0781.308 1.0024.85C
ATOM2395CGARGC 58 25.1013.1912.305 1.00 22.80C
ATOM2396CDARGC 58 24.7862.5213.637 1.00 22.21C
ATOM2397NEARGC 58 23.8373.3474.3381.0021.99N
ATOM2398CZARGC 58 22.9262.9735.2401.00 19.53C
ATOM2399NHl ARG C 58 22.7631.7325.7011.00 17.53N
ATOM2400NH2ARGC 58 22.1713.9295.7111.0021.80N
ATOM2401CARGC 58 23.0762.934-1.1191.0025.78C
ATOM2402OARGC 58 22.7821.783-1.5041.0025.72O
ATOM2403NALAC 59 22.3874.015-1.4891.0025.39N
ATOM2404CAALAC 59 21.1793.863-2.2961.00 26.62C
ATOM2405CBALAC 59 20.2835.090-2.2171.00 26.36C
ATOM2406CALAC 59 21.5893.553-3.7001.0027.46C
ATOM2407OALAC 59 20.9782.716-4.3321.00 28.68O
ATOM2408NSERC 60 22.6824.177-4.1521.0028.92N
ATOM2409CASERC 60 23.3123.905-5.4701.00 28.38C
ATOM2410CBSERC 60 24.4534.898-5.7731.0028.04C
ATOM2411OGSERC 60 23.9526.195-6.1091.00 27.38O
ATOM2412CSERC 60 23.8412.497-5.5011.0029.03C
ATOM2413OSERC 60 23.5971.751-6.4331.0028.91O
ATOM2414NTRPC 61 24.5842.119-4.4651.0029.73N
ATOM2415CATRPC 61 25.0260.748-4.3751.0030.08C
ATOM2416CBTRPC 61 25.8610.523-3.1281.0029.96C
ATOM2417CGTRPC 61 26.512-0.799-3.0901.0029.15C
[0296]ATOM2418CDl TRPC 61 27.746 -1.115 -3.567 1.0028.87CATOM2419NEl TRPC 61 28.018 -2.448 -3.340 1.0029.37N
ATOM2420CE2TRPC 61 26.939 -3.017 -2.707 1.0031.46C
ATOM2421CD2TRPC 61 25.964 -2.011 -2.548 1.00 30.34C
ATOM2422CE3TRPC 61 24.751 -2.341 -1.937 1.00 30.35C
ATOM2423CZ3TRPC 61 24.542 -3.655 -1.519 1.00 30.16C
ATOM2424CIE2TRPC 61 25.513 -4.629 -1.697 1.0029.72C
ATOM2425CZ2TRPC 61 26.722 -4.341 -2.285 1.00 32.43C
ATOM2426C TRPC 61 23.844 -0.243 -4.439 1.0030.32C
ATOM2427O TRPC 61 23.950 -1.265 -5.075 1.00 30.37O
ATOM2428N ARGC 62 22.734 0.056 -3.781 1.00 31.07N
ATOM2429CA ARGC 62 21.627 -0.895 -3.723 1.0032.37 C
ATOM2430CB ARGC 62 20.598 -0.500 -2.677 1.00 32.37C
ATOM2431CG ARGC 62 20.886 -1.043 -1.333 1.00 34.28 C
ATOM2432CD ARGC 62 19.701 -0.820 -0.464 1.00 37.25 C
ATOM2433NE ARGC 62 19.563 0.577 -0.115 1.0041.15N
ATOM2434CZ ARGC 62 20.313 1.209 0.788 1.00 43.55 C
ATOM2435NHl ARGC 62 20.094 2.498 1.028 1.0044.70N
ATOM2436NH2ARGC 62 21.275 0.564 1.441 1.0042.15N
ATOM2437C ARGC 62 20.899 -1.122 -5.037 1.00 32.98C
ATOM2438O ARGC 62 20.561 -2.247 -5.336 1.00 33.75O
ATOM2439N ILEC 63 20.618 -0.081 -5.812 1.00 33.54N
ATOM2440CA ILEC 63 19.967 -0.328 -7.114 1.00 34.27C
ATOM2441CB ILEC 63 19.203 0.908 -7.693 1.00 34.66C
ATOM2442CGl ILE C 63 20.162 1.956 -8.253 1.00 35.57C
ATOM2443CDl ILE C 63 20.696 2.875 -7.230 1.00 34.40C
ATOM2444CG2ILEC 63 18.209 1.490 -6.665 1.00 36.73C
ATOM2445C ILEC 63 20.946 -0.925 -8.147 1.00 33.91C
ATOM2446O ILEC 63 20.553 -1.719 -8.990 1.00 34.21O
ATOM2447N VALC 64 22.219 -0.550 -8.059 1.00 34.05N
ATOM2448CA VALC 64 23.245 -1.104 -8.942 1.00 34.57C
ATOM2449CB VALC 64 24.599 -0.306 -8.855 1.00 33.83C
ATOM2450CGl VALC 64 25.734 -1.045 -9.519 1.00 32.20C
ATOM2451CG2VALC 64 24.428 1.053 -9.493 1.0031.65C
ATOM2452C VALC 64 23.388 -2.596 -8.663 1.00 36.03C
ATOM2453O VALC 64 23.352 -3.417 -9.588 1.00 36.20O
ATOM 2454N SERC 65 23.502 -2.930 -7.376 1.00 37.12N
ATOM 2455CA SERC 65 23.570 -4.307 -6.926 1.00 38.72C
ATOM 2456CB SERC 65 23.572 -4.358 -5.411 1.00 38.46C
ATOM 2457OG SERC 65 24.334 -5.450 -5.002 1.00 40.16O
ATOM 2458C SERC 65 22.390 -5.141 -7.457 1.00 39.64C
ATOM 2459O SERC 65 22.593 -6.209 -8.026 1.00 40.30O
ATOM 2460N SERC 66 21.172 -4.642 -7.294 1.0040.79N
ATOM 2461CA SERC 66 19.995 -5.402 -7.667 1.0042.51C
[0297]ATOM2462CB SERC 66 18.783 -4.869 -6.910 1.0042.40CATOM2463OG SERC 66 18.088 -3.922 -7.682 1.00 42.54O
ATOM2464C SERC 66 19.722 -5.424 -9.180 1.0044.02C
ATOM2465O SERC 66 18.809 -6.121 -9.646 1.0044.94O
ATOM2466N ILEC 67 20.475 -4.634 -9.943 1.00 45.57N
ATOM2467CA ILEC 67 20.410 -4.680-11.405 1.00 46.59C
ATOM2468CB ILEC 67 20.632 -3.272-12.080 1.00 46.48C
ATOM2469CGl ILE C 67 19.591 -2.237-11.626 1.00 46.88C·ATOM2470CDl ILE C 67 18.215 -2.788-11.263 1.00 49.69C
ATOM2471CG2ILEC 67 20.657 -3.354-13.616 1.0045.71C
ATOM2472C ILEC 67 21.474 -5.673-11.843 1.0047.65C
ATOM2473O ILEC 67 21.307 -6.384-12.837 1.00 48.02O
ATOM2474N GLUC 68 22.555 -5.736-11.069 1.0049.06N
ATOM2475CA GLUC 68 23.630 -6.694-11.282 1.00 50.47C
ATOM2476CB GLUC 68 24.769 -6.445 -10.291 1.00 50.48C
ATOM2477CG GLUC 68 26.018 -7.243 -10.561 1.0049.18C
ATOM2478CD GLUC 68 27.223 -6.644 -9.906 1.0049.73C
ATOM2479OEl GLU C 68 27.180 -5.470 -9.488 1.00 50.52O
ATOM2480OE2GLUC 68 28.236 -7.346 -9.811 1.0051.15O
ATOM2481C GLU C 68 23.121 -8.126-11.166 1.00 51.91C
ATOM2482O GLUC 68 23.576 -9.001 -11.906 1.00 52.19O
ATOM2483N GLNC 69 22.167 -8.332-10.252 1.00 53.79N
ATOM2484CA GLNC 69 21.456 -9.605 -10.055 1.00 55.33C
ATOM2485CB GLNC 69 20.922 -9.699 -8.620 1.00 55.06C
ATOM2486CG GLNC 69 19.584 -8.994 -8.351 1.00 55.61C
ΑΓΟΜ2487CD GLNC 69 19.192 -9.021 -6.872 1.00 56.30C
ATOM2488OEl GLN C 69 19.786 -9.760 -6.074 1.00 58.73O
ATOM2489NE2GLNC 69 18.194 -8.217 -6.501 1.00 55.92N
ATOM2490C GLNC 69 20.329 -9.863-11.073 1.00 56.44C
ATOM2491O GLNC 69 20.045-11.014-11.419 1.00 56.82O
ATOM2492N LYSC 70 19.682 -8.806-11.551 1.00 57.76N
ATOM2493CA LYSC 70 18.732 -8.954-12.651 1.0059.15C
ATOM2494CB LYSC 70 18.080 -7.612-12.983 1.00 59.14C
ATOM2495CG LYSC 70 16.680 -7.740-13.571 1.00 60.78C
ATOM2496CD LYSC 70 15.616 -7.957 -12.492 1.00 62.84C
ATOM2497CE LYSC 70 15.181 -6.624-11.860 1.00 64.34C
ATOM2498NZ LYSC 70 14.092 -6.762-10.842 1.00 63.56N
ATOM2499C LYSC 70 19.453 -9.530-13.885 1.00 59.76C
ATOM2500O LYSC 70 19.002-10.511 -14.484 1.0060.09O
ATOM2501N GLUC 71 20.597 -8.937-14.222 1.00 60.30N
ATOM2502CA GLUC 71 21.383 -9.319-15.395 1.00 60.83C
ATOM2503CB GLUC 71 22.386 -8.212-15.734 1.0060.67C
ATOM2504CG GLUC 71 21.720 -6.945 -16.208 1.00 60.18C
ATOM2505CD GLUC 71 20.821 -7.195-17.398 1.00 59.54C
[0298]ATOM2506OEl GLUC 71 19.593 -7.294-17.216 1.00 58.63OATOM2507OE2GLUC 71 21.355 -7.323-18.511 1.00 58.31O
ATOM2508C GLUC 71 22.092-10.671 -15.290 1.00 61.43C
ATOM2509O GLUC 71 22.383-11.297-16.314 1.0061.54O
ATOM2510N GLUC 72 22.382-Π.109-14.063 1.00 62.21N
ATOM2511CA GLUC 72 22.896-12.458-13.819 1.0062.87C
ATOM2512CB GLUC 72 23.326-12.630-12.363 1.0062.94C
ATOM2513CG GLUC 72 24.836-12.692-12.185 1.00 63.40C·ATOM2514CD GLUC 72 25.377-14.111 -12.242 1.00 63.71C
ATOM2515OEl GLUC 72 26.050-14.475-13.243 1.00 62.68O
ATOM2516OE2GLUC 72 25.131 -14.862-11.273 1.00 63.91O
ATOM2517C GLUC 72 21.901 -13.551 -14.227 1.00 63.29C
ATOM2518O GLUC 72 22.227-14.395-15.061 1.00 63.37O
ATOM2519N GLYC 73 20.696-13.524-13.652 1.00 63.68N
ATOM2520CA GLYC 73 19.627-14.463-14.017 1.00 63.90C
ATOM2521C GLYC 73 19.020-14.092-15.361 1.00 64.09C
ATOM2522O GLYC 73 17.812-13.854-15.470 1.00 64.20O
ATOM2523N ARGC 74 19.883-14.052-16.374 1.00 63.92N
ATOM2524CA ARGC 74 19.592-13.553-17.719 1.00 63.87C
ATOM2525CB ARGC 74 19.360-12.038-17.706 1.00 63.78C
ATOM2526CG ARGC 74 17.910-11.601 -17.616 1.0063.51C
ATOM2527CD ARGC 74 17.723-10.186-18.146 1.00 63.76C
ATOM2528NE ARGC 74 16.789 -9.429-17.315 1.00 66.14N
ATOM2529CZ ARGC 74 16.219 -8.273 -17.660 1.00 67.89C
ATOM2530NHl ARG C 74 16.472 -7.716-18.844 1.00 68.73N
ATOM2531NH2ARGC 74 15.382 -7.669-16.817 1.00 67.45N
ATOM2532C ARGC 74 20.789-13.870-18.620 1.00 63.83C
ATOM2533O ARGC 74 20.729-13.706-19.842 1.00 63.93O
ATOM2534N GLYC 75 21.877-14.315-17.994 1.00 63.86N
ATOM2535CA GLYC 75 23.098-14.745-18.682 1.00 63.90C
ATOM2536C GLYC 75 23.816-13.663-19.468 1.00 63.95C
ATOM2537O GLYC 75 24.430-13.945 -20.509 1.00 64.22O
ATOM2538N ASNC 76 23.752-12.425-18.980 1.00 63.41N
ATOM2539CA ASNC 76 24.357-11.309-19.700 1.00 62.96C
ATOM2540CB ASNC 76 23.477-10.061 -19.603 1.00 62.93C
ATOM2541CG ASNC 76 22.215-10.163 -20.458 1.0062.77C
ATOM2542ODl ASNC 76 22.012 -9.369 -21.373 1.00 63.52O
ATOM2543ND2ASNC 76 21.374-11.141-20.167 1.0061.52N
ATOM2544C ASNC 76 25.786-11.041 -19.240 1.00 62.63C
ATOM2545O ASNC 76 26.029-10.168-18.410 1.00 62.57O
ATOM2546N GLUC 77 26.719-11.819-19.786 1.00 62.22N
ATOM2547CA GLUC 77 28.132-11.730-19.428 1.00 61.92C
ATOM2548CB GLUC 77 29.031 -12.524 -20.404 1.00 62.10C
ATOM2549CG GLUC 77 28.955 -14.054 -20.307 1.00 64.21C
[0299]ATOM2550CD GLUC 77 28.236-14.705-21.500 1.00 67.32CATOM2551OEl GLU C 77 28.400-14.216-22.647 1.00 67.87O
ATOM2552OE2GLUC 77 27.519-15.719-21.290 1.00 67.70O
ATOM2553C GLUC 77 28.570-10.275-19.407 1.00 60.89C
ATOM2554O GLUC 77 29.077 -9.794-18.392 1.0061.05O
ATOM2555N GLUC 78 28.346 -9.579 -20.523 1.00 59.68N
ATOM2556CA GLUC 78 28.860 -8.215-20.711 1.00 58.34 C
ATOM2557CB GLUC 78 28.805 -7.771 -22.180 1.00 58.21C
ATOM2558CG GLUC 78 29.525 -8.686 -23.148 1.00 59.26 C
ATOM2559CD GLUC 78 28.591 -9.648 -23.882 1.00 60.87 C
ATOM2560OEl GLU C 78 28.774 -9.809 -25.108 1.00 62.39O
ATOM2561OE2 GLU C 78 27.678-10.235-23.255 1.00 60.93O
ATOM2562C GLUC 78 28.158 -7.193-19.821 1.00 57.04C
ATOM2563O GLUC 78 28.809 -6.291 -19.306 1.00 56.91O
ATOM2564N HISC 79 26.838 -7.327-19.654 1.00 55.52N
ATOM2565CA HISC 79 26.102 -6.441 -18.756 1.00 53.78C
ATOM2566CB HISC 79 24.591 -6.701 -18.789 1.00 53.55C
ATOM2567CG HISC 79 23.897 -6.097-19.980 1.00 53.14C
ATOM2568NDl HIS C 79 22.615 -6.440 -20.353 1.00 54.71N
ATOM2569CEl HIS C 79 22.265 -5.760 -21.431 1.00 52.95C
ATOM2570NE2 HIS C 79 23.280 -4.988-21.777 1.00 53.45N
ATOM2571CD2 HIS C 79 24.311 -5.177 -20.887 1.00 52.77C
ATOM2572C HISC 79 26.688 -6.562-17.356 1.00 52.90C
ATOM2573O HIS C 79 27.262 -5.595-16.862 1.00 52.55O
ATOM2574N VALC 80 26.585 -7.761 -16.764 1.00 52.08N
ATOM2575CA VALC 80 27.205 -8.114-15.465 1.00 50.73C
ATOM2576CB VALC 80 27.177 -9.666-15.188 1.00 50.95C
ATOM2577CGl VALC 80 28.051 -10.036-13.967 1.00 50.63C
ATOM2578CG2VALC 80 25.751 -10.174-14.994 1.0049.50C
ATOM2579C VALC 80 28.646 -7.588-15.315 1.00 50.19C
ATOM2580O VALC 80 28.989 -7.043 -14.272 1.0049.76O
ATOM2581N THRC 81 29.456 -7.744-16.369 1.00 49.17N
ATOM2582CA THRC 81 30.863 -7.328-16.391 1.0048.37C
ATOM2583CB THRC 81 31.545 -7.699-17.747 1.0048.48C
ATOM2584OGl THR C 81 31.400 -9.103-17.994 1.00 48.91O
ATOM2585CG2THRC 81 33.041 -7.324-17.755 1.0048.87C
ATOM2586C THRC 81 31.021 -5.829-16.152 1.0047.70C
ATOM2587O THRC 81 31.849 -5.408-15.328 1.0048.05O
ΑΓΟΜ2588N LEUC 82 30.230 -5.047-16.897 1.0046.44N
ATOM2589CA LEUC 82 30.168 -3.584-16.807 1.0044.57C
ATOM2590CB LEUC 82 29.419 -3.032-18.027 1.0044.74C
ΑΊΌΜ2591CG LEUC 82 30.175 -3.023 -19.362 1.00 42.82C
ATOM2592CDl LEU C 82 29.237 -2.741 -20.532 1.0041.59C
ATOM2593CD2LEUC 82 31.336 -2.023 -19.309 1.0041.90C
[0300]ATOM2594C LEUC 82 29.501 -3.088 -15.524 1.0043.70CATOM2595O LEUC 82 29.930 -2.096 -14.932 1.00 43.55O
ATOM2596N ILEC 83 28.463 -3.779-15.084 1.0042.77N
ATOM2597CA ILEC 83 27.801 -3.417-13.825 1.0042.49C
ATOM2598CB ILEC 83 26.435 -4.145-13.612 1.0041.94C
ATOM2599CGl ILE C 83 25.521 -3.981 -14.832 1.0041.97C
ATOM2600CDl ILE C 83 24.334 -4.906-14.814 1.00 41.81C
ATOM2601CG2ILEC 83 25.716 -3.588-12.384 1.0041.94C
ATOM2602C ILEC 83 28.720 -3.645 -12.605 1.00 42.40C
ATOM2603O ILEC 83 28.639 -2.905-11.629 1.0042.17O
ATOM2604N LYSC 84 29.590 -4.653 -12.680 1.0042.23N
ATOM2605CA LYSC 84 30.383 -5.070-11.531 1.0043.08C
ATOM2606CB LYSC 84 30.897 -6.496-11.725 1.0043.65C
ATOM2607CG LYSC 84 31.721 -7.109-10.587 1.0044.72C
ATOM2608CD LYSC 84 31.725 -8.645 -10.709 1.0045.77C
ATOM2609CE LYSC 84 30.404 -9.263-10.150 1.00 50.93C
ATOM2610NZ LYSC 84 29.821-10.423-10.938 1.00 53.08N
ATOM2611C LYSC 84 31.518 -4.098-11.328 1.00 42.18C
ATOM2612O LYSC 84 31.865 -3.787-10.188 1.0043.17O
ATOM2613N GLUC 85 32.079 -3.602 -12.430 1.0041.10N
ATOM2614CA GLUC 85 33.041 -2.501 -12.372 1.00 40.36 C
ATOM2615CB GLUC 85 33.680 -2.262-13.743 1.0041.03 C
ATOM2616CG GLUC 85 34.663 -3.346-14.159 1.00 45.25 C
ATOM2617CD GLUC 85 35.759 -3.581 -13.105 1.00 50.09 C
ATOM2618OEl GLU C 85 36.510 -2.605 -12.771 1.00 53.10O
ATOM2619OE2GLUC 85 35.860 -4.740-12.610 1.00 49.39O
ATOM2620C GLUC 85 32.416 -1.203-11.856 1.00 38.79C
ATOM2621O GLUC 85 33.049 -0.464-11.084 1.00 38.22O
ATOM2622N TYRC 86 31.182 -0.918-12.294 1.00 37.00N
ATOM2623CA TYRC 86 30.439 0.246-11.794 1.00 35.36 C
ATOM2624CB TYRC 86 29.098 0.435 -12.539 1.00 34.74 C
ATOM2625CG TYRC 86 28.516 1.836-12.431 1.00 32.56 C
ATOM2626CDl TYRC 86 29.182 2.937-12.980 1.00 32.32C
ATOM2627CEl TYRC 86 28.651 4.214 -12.874 1.00 32.62C
ATOM2628CZ TYRC 86 27.437 4.396-12.201 1.0031.36 C
ATOM2629OH TYRC 86 26.903 5.648-12.059 1.00 29.90 O
ATOM2630CE2TYRC 86 26.774 3.322-11.643 1.00 30.05C
ATOM2631CD2TYRC 86 27.319 2.052-11.763 1.00 30.63C
ATOM2632C TYRC 86 30.261 0.111 -10.272 1.00 34.76C
ATOM2633O TYRC 86 30.761 0.944 -9.513 1.00 34.05 O
ATOM2634N ARGC 87 29.624 -0.990 -9.868 1.00 34.76 N
ATOM2635CA ARGC 87 29.489 -1.411 -8.467 1.00 34.69 C
ATOM2636CB ARGC 87 28.930 -2.819 -8.335 1.00 33.89 C
ATOM2637CG ARGC 87 28.626 -3.136 -6.839 1.00 35.31 C
[0301]ATOM2638CD ARGC 87 27.763 -4.363 -6.547 1.00 34.77CATOM2639NE ARGC 87 28.291-5.631 -7.063 1.0037.27N
ATOM2640CZ ARGC 87 29.493-6.150 -6.795 1.0039.90C
ATOM2641NHl ARGC 87 30.377-5.497 -6.0351.0041.03N
ATOM2642NH2ARGC 87 29.839-7.330 -7.3151.0037.58N
ATOM2643C ARGC 87 30.762-1.330 -7.6471.00 34.59C
ATOM2644O ARGC 87 30.716-0.863 -6.5051.00 34.82O ATOM2645N GLYC 88 31.872-1.812 -8.2051.00 34.90N
ATOM2646CA GLYC 88 33.212-1.657 -7.5741.00 35.39C
ATOM2647C GLYC 88 33.631-0.227 -7.3061.00 35.33C
ATOM2648O GLYC 88 34.3220.052 -6.3371.00 37.09O
ATOM2649N LYSC 89 33.2080.696 -8.1611.00 35.43N
ATOM2650CA LYSC 89 33.631 2.094 -8.0531.00 34.76C
ATOM2651CB LYSC 89 33.5832.771 -9.4411.00 35.05C
ATOM2652CG LYSC 89 33.135 4.237 -9.4991.00 37.29C
ATOM2653CD LYSC 89 33.953 5.021 -10.5561.00 40.54C
ATOM2654CE LYSC 89 33.4374.848 -12.0061.0042.15C
ATOM2655NZ LYSC 89 34.355 5.561 -12.9821.0041.30N
ATOM2656C LYSC 89 32.8542.850 -6.9531.00 33.87C
ATOM2657O LYSC 89 33.4023.734 -6.2831.00 33.34O
ATOM2658N ILEC 90 31.5852.473 -6.7711.00 33.21N
ATOM2659CA ILEC 90 30.7592.929 -5.6501.0031.05C
ATOM2660CB ILEC 90 29.2712.551 -5.8061.0031.24C
ATOM2661CGl ILE C 90 28.7702.980 -7.2021.0029.33C
ATOM2662CDl ILE C 90 27.3792.500 -7.6171.00 30.88C
ATOM2663CG2 TLE C 90 28.4543.199 -4.6601.0028.95C
ATOM2664C ILEC 90 31.3272.366 -4.3541.0031.25C
ATOM2665O ILEC 90 31.5683.148 -3.4161.00 31.51O
ATOM2666N GLUC 91 31.583 1.051 -4.3241.0030.50N
ATOM2667CA GLUC 91 32.227 0.382 -3.174 1.0031.38C
ATOM2668CB GLUC 91 32.389-1.114 -3.4371.0031.22C
ATOM2669CG GLUC 91 31.057-1.880 -3.661 1.00 32.20C
ATOM2670CD GLUC 91 31.236-3.384 -3.721 1.00 32.18C
ATOM2671OEl GLUC 91 32.372-3.833 -3.6381.00 34.88O
ATOM2672OE2GLUC 91 30.245-4.135 -3.8571.00 36.87O
ATOM2673C GLUC 91 33.592 1.042 -2.7611.0031.69C
ATOM2674O GLUC 91 33.962 1.069 -1.5771.0031.67O
ATOM2675N ALAC 92 34.312 1.631 -3.7181.0031.37N
ATOM2676CA ALAC 92 35.535 2.356 -3.329 1.00 30.84C
ATOM2677CB ALAC 92 36.428 2.641 -4.542 1.0031.22C
ATOM2678C ALAC 92 35.2003.621 -2.5901.00 30.07C
ATOM2679O ALAC 92 35.9063.990 -1.6431.0031.00O
ATOM2680N GLUC 93 34.130 4.298 -3.0131.00 29.42N
ATOM2681CA GLUC 93 33.682 5.518 -2.334 1.0029.08C
[0302]ATOM2682CB GLUC 93 32.628 6.288-3.117 1.00 29.09CATOM2683CG GLUC 93 32.944 6.558-4.570 1.0029.13C
ATOM2684CD GLUC 93 32.018 7.601-5.103 1.0026.09C
ATOM2685OEl GLUC 93 32.2708.186-6.170 1.0026.60O ATOM2686OE2GLUC 93 31.0397.886-4.402 1.0027.34O
ATOM2687C GLUC 93 33.1515.212-0.944 1.0029.23C
ATOM2688O GLUC 93 33.5615.8690.041 1.0028.12O
ATOM2689N LEUC 94 32.2244.238-0.897 1.00 28.87N
ATOM2690CA LEUC 94 31.709 3.653 0.340 1.00 28.71C
ATOM2691CB LEUC 94 30.8992.399 0.050 1.0027.03C
ATOM2692CG LEUC 94 29.5112.462-0.590 1.0027.39C
ATOM2693CDl LEUC 94 28.9741.076-0.873 1.00 21.28C
ATOM2694CD2LEUC 94 28.5243.2170.315 1.0026.27C
ATOM2695C LEUC 94 32.8143.3271.362 1.00 28.55C
ATOM2696O LEUC 94 32.6853.6862.509 1.00 30.17O
ATOM2697N SERC 95 33.8692.6380.952 1.00 29.82N
ATOM2698CA SERC 95 35.0402.333 1.813 1.0031.10C
ATOM2699CB SERC 95 36.0871.5171.047 1.0031.37C
ATOM2700OG SERC 95 35.5690.291 0.541 1.00 32.61O
ATOM2701C SERC 95 35.7403.5812.341 1.0031.88C
ATOM2702O SERC 95 36.0783.6603.519 1.00 33.27O
ATOM2703N LYSC 96 35.9714.5381.447 1.00 32.56N
ATOM2704CA LYSC 96 36.6975.7561.730 1.00 33.24C
ATOM2705CB LYSC 96 37.1466.3740.405 1.00 32.38C
ATOM2706CG LYSC 96 37.3717.8500.443 1.00 34.41C
ATOM2707CD LYSC 96 37.9218.418-0.873 1.00 36.21C
ATOM2708CE LYSC 96 38.3429.886-0.636 1.00 38.65C
ATOM2709NZ LYSC 96 38.18610.749-1.854 1.0042.29N
ATOM2710C LYSC 96 35.9086.7502.623 1.00 33.65C
ATOM2711O LYSC 96 36.4997.4693.481 1.00 32.92O
ATOM2712N ILEC 97 34.5806.7742.453 1.00 33.11N
ATOM2713CA ILEC 97 33.7437.5903.317 1.00 32.94C
ATOM2714CB ILEC 97 32.2877.7942.770 1.00 33.27C
ATOM2715CGl ILEC 97 32.2858.5351.416 1.00 32.65C
ATOM2716CDl ILE C 97 31.0088.2850.570 1.0031.76C
ATOM2717CG2ILEC 97 31.3968.5443.792 1.00 32.67C
ATOM2718C ILEC 97 33.7786.9954.744 1.00 33.41C
ATOM2719O ILEC 97 33.9477.7425.712 1.00 32.79O
ATOM2720N CYSC 98 33.6575.6594.852 1.0033.50N
ATOM2721CA CYSC 98 33.6544.986 6.160 1.00 32.82C
ATOM2722CB CYSC 98 33.2843.515 6.034 1.00 32.21C
ATOM2723SG CYSC 98 31.5673.180 5.481 1.0030.60S
ATOM2724C CYSC 98 35.0055.1076.866 1.00 33.28C
ATOM2725O CYSC 98 35.0455.2448.073 1.00 32.33O
[0303]ATOM2726N ASPC 9936.0965.039 6.1061.00 33.48NATOM2727CA ASPC 99 37.4265.168 6.684 1.00 34.61C
ATOM2728CB ASPC 99 38.4944.805 5.632 1.00 34.96C
ATOM2729CG ASPC 99 39.7764.256 6.256 1.00 39.85C
ATOM2730ODl ASP C 9939.9912.997 6.2241.0042.43O
ATOM2731OD2ASPC 9940.5715.084 6.7841.0040.56O
ATOM2732C ASPC 9937.6156.575 7.2671.00 33.79C
ATOM2733O ASPC 9938.1646.743 8.3511.00 34.15O·ATOM2734N GLYC 10037.1207.587 6.5611.00 33.53N
ATOM2735CA GLYC 100 37.2648.957 7.000 1.00 32.73C
ATOM2736C GLYC10036.6739.177 8.3751.00 33.44C
ATOM2737O GLYC 10037.3499.748 9.2691.00 34.05O
ATOM2738N ILEC 10135.4158.743 8.5521.00 32.16N
ATOM2739CA ILEC 10134.7148.913 9.8341.0031.69C
ATOM2740CB ILE C 10133.1708.870 9.7191.00 30.51C
ATOM2741CGl ILE C 10132.5169.033 11.0711.00 30.56C
ATOM2742CDl ILEC 10132.18210.467 11.4461.0030.71C
ATOM2743CG2ILEC 10132.6497.565 9.0581.0031.97C
ATOM2744C 止 EC 10 丨35.2327.996 10.9461.0031.79C
ATOM2745O ILEC 10135.3478.422 12.0751.0031.81O
ATOM2746N LEUC 10235.5796.761 10.6211.00 32.02N
ATOM2747CA LEUC10236.0335.813 11.643 1.00 32.62C
ATOM2748CB LEUC 10236.0944.397 11.067 1.00 32.56C
ATOM2749CG LEUC10235.0303.284 11.312 1.0031.85C
ATOM2750CDl LEU C10233.8273.656 12.1491.00 30.92C
ATOM2751CD2LEUC10234.6142.657 9.9931.0031.99C
ATOM2752C LEU C10237.3856.244 12.2411.00 33.31C
ATOM2753O LEU C10237.5816.148 13.4511.00 33.99O
ATOM2754N LYS C10338.2986.732 11.3971.00 33.21N
ATOM2755CA LYS C 10339.5677.332 11.8801.00 33.12C
ATOM2756CB LYSC 10340.4767.741 10.725].00 32.09C
ATOM2757CG LYS C 10341.4806.678 10.4941.00 32.94C
ATOM2758CD LYS C 10341.7616.375 9.0371.00 32.72C
ATOM2759CE LYS C10342.4655.032 8.9671.00 30.55C
ATOM2760NZ LYSC 10343.1404.907 7.7081.0031.00N
ATOM2761C LYSC 10339.3098.482 12.8301.00 32.56C
ATOM2762O LYS C10339.7318.442 13.9761.00 33.19O
ATOM2763N LEU C10438.5799.474 12.3641.00 32.25N
ATOM2764CA LEU C10438.12810.563 13.205 1.00 33.12C
ATOM2765CB LEUC 10437.12311.414 12.418 1.00 32.57C
ATOM2766CG LEUC10436.54612.617 13.148 1.00 33.88C
ATOM2767CDl LEU C10437.66913.653 13.6031.00 33.13C
ATOM2768CD2LEUC10435.53713.267 12.2531.00 33.98C
ATOM2769C LEU C10437.54210.141 14.5761.00 33.70C
[0304]ATOM2770O LEUC 104 37.92410.674 15.627 1.00 33.72OATOM2771N LEUC 105 36.5899.212 14.550 1.0033.86N
ATOM2772CA LEU C105 36.0278.576 15.761 1.00 34.31C
ATOM2773CB LEU C105 35.0137.485 15.339 1.00 32.74C
ATOM2774CG LEU C105 33.5087.597 15.529 1.0031.78C
ATOM2775CDl LEU C105 32.9598.977 15.894 1.0028.19C
ATOM2776CD2LEUC105 32.7797.024 14.335 1.00 30.84C
ATOM2777C LEUC 105 37.0947.958 16.691 1.00 34.80C
ATOM2778O LEUC 105 37.0498.144 17.897 1.0035.39O
ATOM2779N ASPC 106 38.0367.215 16.117 1.00 36.30N
ATOM2780CA ASPC 106 39.0336.470 16.892 1.00 37.92C
ATOM2781CR ASPC 106 39.6775.359 16.044 1.00 37.96C
ATOM2782CG ASPC 106 38.7424.132 15.819 1.0040.44C
ATOM2783ODl ASP C106 37.7483.930 16.577 1.00 39.57O
ATOM2784OD2ASPC106 39.0383.344 14.877 1.00 42.25O
ATOM2785C ASPC106 40.1207.396 17.450 1.00 38.77C
ATOM2786O ASPC 106 40.7157.115 18.490 1.00 38.74O
ATOM2787N SERC 107 40.3578.510 16.766 1.00 39.46N
ATOM2788CA SERC 107 41.4399.416 17.133 1.0040.62C
ATOM2789CB SERC 107 42.1349.953 15.873 1.0041.06C
ATOM2790OG SERC 107 41.21010.672 15.054 1.00 43.71O
ATOM2791C SERC 107 40.96210.555 18.031 1.0040.54C
ATOM2792O SERC 107 41.61810.881 19.026 1.0041.23O
ATOM2793N HIS C 108 39.81711.147 17.696 1.00 40.09N
ATOM2794CA HIS C 108 39.31112.296 18.431 1.00 39.38C
ATOM2795CB HIS C 108 39.13913.494 17.492 1.00 39.82C
ATOM2796CG HIS C 108 40.42914.029 16.947 1.00 38.56C
ATOM2797NDl HIS C108 41.25113.293 16.120 1.00 37.80N
ATOM2798CEl HIS C 108 42.30414.018 15.795 1.00 35.37C
ATOM2799NE2 HIS C 108 42.19315.193 16.385 1.00 35.98N
ATOM2800CD2HISC 108 41.02815.228 17.105 1.00 36.15C
ATOM2801C HIS C 108 38.01712.064 19.183 1.00 39.55C
ATOM2802O HlSC 108 37.96712.249 20.399 1.0039.15O
ATOM2803N LEUC109 36.96511.664 18.461 1.00 39.66N
ATOM2804CA LEUC 109 35.60411.683 19.010 1.00 39.58C
ATOM2805CB LEUC 109 34.55711.447 17.919 1.00 39.27C
ATOM2806CG LEUC 109 33.98212.637 17.122 1.00 39.77C
ATOM2807CDl LEUC109 33.80612.236 15.680 1.00 37.93C
ATOM2808CD2LEUC109 34.83113.911 17.207 1.00 39.97C
ATOM2809C LEUC 109 35.39810.696 20.145 1.0040.17C
ATOM2810O LEUC109 34.75411.022 21.131 1.00 40.67O
ATOM2811N VALC110 35.9339.492 20.018 1.0040.77N
ATOM2812CA VALC HO 35.7148.503 21.071 1.00 42.44C
ATOM2813CB VALC HO 35.8197.042 20.554 1.0042.06C
[0305]ATOM2814CGl VALC HO 35.7876.062 21.7061.00 42.21CATOM2815CG2 VALC 110 34.6686.759 19.6021.00 40.83C
ATOM2816C VALC110 36.5028.796 22.3751.0043.14C
ATOM2817O YALC 110 35.8698.897 23.4241.00 43.71O
ATOM2818N PRO C 111 37.8539.008 22.2981.00 43.94N
ATOM2819CA PROC 111 38.6749.324 23.4851.0043.89C
ATOM2820CB PROC 111 40.0809.460 22.9071.0043.74C
ATOM2821CG PROC 111 40.0448.622 21.6641.0044.47C
ATOM2822CD PROC 111 38.7048.942 21.0941.0043.79C
ATOM2823C PROC 111 38.29510.622 24.1841.00 44.26C
ATOM2824O PROC 111 38.46910.748 25.3931.00 44.73O
ATOM2825N SERC 112 37.79011.588 23.4411.00 44.42N
ATOM2826CA SERC 112 37.47212.863 24.0401.0044.20C
ATOM2827CB SERC 112 37.51913.964 23.0021.0044.52C
ATOM2828OG SERC 112 36.26814.088 22.3551.00 46.34O
ATOM2829C SERC112 36.11112.869 24.7151.0044.17C
ATOM2830O SERC112 35.77213.856 25.3861.0044.10O
ATOM2831N SERC113 35.33211.791 24.5251.00 43.49N
ATOM2832CA SERC 113 33.95211.707 25.0481.0042.87C
ATOM2833CB SERC 113 33.19010.509 24.4631.00 42.85C
ATOM2834OG SERC 113 33.22910.503 23.0611.00 41.85O
ATOM2835C SERC 113 33.96311.577 26.5551.0042.79C
ATOM2836O SERC113 34.60410.682 27.1081.00 42.67O
ATOM2837N THRC 114 33.22312.465 27.2011.00 42.96N
ATOM2838CA THRC 114 33.16512.541 28.6461.00 43.22C
ATOM2839CB THRC 114 33.60613.964 29.1141.0043.06C
ATOM2840OGl THRC 114 34.64213.852 30.0941.00 43.89O
ATOM2841CG2THRC 114 32.44514.827 29.6121.00 42.83C
ATOM2842C THRC 114 31.77712.092 29.1561.00 42.98C
ATOM2843O THRC 114 31.67011.078 29.8441.0043.23O
ATOM2844N ALAC 115 30.72012.811 28.7871.0042.83N
ATOM2845CA ALAC 115 29.37712.395 29.1531.0043.06C
ATOM2846CB ALAC 115 28.33413.381 28.6261.0043.24C
ATOM2847C ALAC 115 29.10110.962 28.6561.00 42.86C
ATOM2848O ALAC 115 29.75810.470 27.7341.0043.02O·ATOM2849N ALAC116 28.16810.282 29.3171.0042.52N
ATOM2850CA ALAC 116 27.7608.948 28.9111.0041.77C
ATOM2851CB ALAC 116 26.8798.300 29.9871.0041.60C
ATOM2852C ALAC 116 27.0129.046 27.5921.0040.93C
ATOM2853O ALAC 116 27.2178.233 26.7031.0041.08O
ATOM2854N GLUC 117 26.14010.043 27.4691.0040.70N
ATOM2855CA GLUC 117 25.32110.180 26.2481.0040.22C
ATOM2856CB GLUC117 24.18811.216 26.4181.00 39.78C
ATOM2857CG GLUC 117 24.45712.625 25.9411.0040.55C
[0306]ATOM 2872 Oo LYSC 119 31.642 8089 26.830 lbo 36.25 O ATOM 2873 CD LYSn119 31.7600SOJS 100 36.13 O ATOM 2874 CE LYSC 119 32.264 8.281 29.291 1.0041.12 O ATOM 2875 NZ LYSC 119 33.540 8.992 28.963 1.00 43.85 M ATOM 2876 n LYS2 19 29.319 6.976 23.792 10031.66 O ATOM 2877 O LYS C119 wvokl^ [020065 100 30.80 〇 ATOM 2878 N VALC 120 28.050 6.873 24.188 1.0030.26 N ATOM 2879 CA VAL012027.0M23,460 1.00 28.41 C ATOM 2880 ClB VALO120 25.668 6.021 24.183 100 27.98 n ATOM 2881 CGl VALC 120 24.573 5.229 23.363 100 26.94 n ATOM 2882 CG2VALC 120 250008 5_425 25.5S1.00 27.24 Π ATOM 2883 C VAL C120 26.907 6.550 22028 1.00 27.78 n ATOM 2884 O VALC 120 27028 5.771 21.103 10027.72 〇 ATOM 2885 Z ΡΗΕΠ121 26.695 7.8500to一00¾ 10028.41¾ ATOM 2886nA ΡΗΕΠ121 26.5s 8.450 20.517 100 28.74 O ATOM 2887 S PHEC 121 26.223 9.966 20.563 1.00 28.31 C· ATOM 28800OQ ^ 25.903 10.584 19.201 1.8 2935 O ATOM 2889 CD1PHE0121 26.901 10.75払一00(025(—*0029.95 η ATOM 2890 CEl PHEC121 26.607 11.331 16.979 1.0028.87 η ATOM 2891 CL PIE0121 25.299 11.752 16.690 100 30.32 C ATOM 2892 CE2PHEC121 24.297 11.592 17.639 1.00 30.22 C ATOM 2893 CD2PHEn121 24.603 11006 18.895 1.00 3209 n ATOM 2894 η ΡΗΕΠ121 27.631 8.075 19.553 10028.58 O ATOM 2895 O PHEC 121 27.342 7.597 18.444 100 28.81 O ATOM 2896 N TYRC 122 280098 8.240 19.981 10027.54 Ni ATOM 2897 CA TYRC122 30.034 7.968 19.102 1.0026.56 C ATOM 28900ηωHYRC 122 31.29500759 19.505 1.0027.62 O ATOM 2899 no -pYRC122 31.105 10.253 19.460 1.0027.12 n ATOM 2900 CDl TYRC 122 30.907 10.926 18.241 1.00 27.40 C ATOM 2901 CEl TYRC 122 30.694 12.325 18.219 100 27.27 Ot0307u
91ATOM2902CZ TYRC12230.71013.042 19.4241.00 27.94C
ATOM2903OH TYRC 12230.51114.409 19.415 1.0028.77O
ATOM2904CE2TYRC12230.89012.38620.6321.0023.70C
ATOM2905CD2TYRC 12231.10911.00520.6371.00 25.60C
ATOM2906C TYRC 12230.3686.48318.9351.0026.26C ATOM2907O TYRC 12230.8456.06017.8651.00 25.73O
ATOM2908N LEU C12330.1415.68719.9771.0024.96N
ATOM2909CA LEUC 12330.3884.26219.8441.0024.99C
ATOM2910CB LEUC 12330.5933.54221.1921.00 24.88C
ATOM2911CG LEU C 12331.8853.85521.9871.0026.30C
ATOM2912CDl LEU C 12331.6423.47123.4351.0026.09C
ATOM2913CD2LEUC12333.0713.05721.4001.0023.02C
ATOM2914C LEUC 12329.2623.61619.0271.0024.53C
ATOM2915O LEUC12329.5382.67718.3371.0024.97O
ATOM2916N LYS C 12428.0354.12519.0841.0024.52N
ATOM2917CA LYSC 12426.9793.68018.1011.00 25.77C
ATOM2918CB LYS C12425.6094.22518.5001.0024.34C
ATOM2919CG LYS C12424.4674.01117.4471.0025.66C
ATOM2920CD LYS C 12423.4305.12017.6271.0022.74C
ATOM2921CE LYS C 12422.7375.44916.2941.0025.88C
ATOM2922NZ LYS C12423.6796.09615.3591.0022.55N
ATOM2923C LYS C 12427.3614.16316.6941.0026.57C
ATOM2924O LYSC 12427.1333.46915.7201.00 27.43O
ATOM2925N METC 12528.0065.33416.6021.00 27.46N
ATOM2926CA METC 12528.363 5.912 15.3021.00 28.43C
ATOM2927CB METC 12528.814 7.361 15.4681.0028.69C
ATOM2928CG METC 12528.975 8.078 14.1881.00 29.43C
ATOM2929SD METC 12529.198 9.82214.3781.00 32.36S
ATOM2930CE METC 12529.09210.278 12.6211.00 28.80C
ATOM2931C METC12529.4185.04214.6181.0028.16C
ATOM2932O METC 12529.3094.71213.4111.0027.92O
ATOM2933N LYS C 12630.3844.59715.4311.0027.49N
ATOM2934CA LYS C 12631.3433.54015.0791.0025.95C
ATOM2935CB LYSC 12632.2203.27716.2871.0026.09C
ATOM2936CG LYS C 12633.3102.28316.0201.0027.32C
ATOM2937CD LYS C 12634.5262.54916.9241.0028.00C
ATOM2938CE LYS C12635.6591.60016.5611.0026.63C
ATOM2939NZ LYS C12636.3862.15415.3511.0027.91N
ATOM2940C LYS C 12630.7152.21614.6331.00 25.81C
ATOM2941O LYS C 12631.0651.66413.5851.00 25.36O
ATOM2942N GLYC 12729.8471.66915.4751.0024.51N
ATOM2943CA GLYC12729.0430.52815.0771.00 24.10C
ATOM2944C GLYC 12728.4480.72413.6891.0021.42C
ATOM2945O GLYC12728.660-0.07612.8681.0020.54O
[0308]ATOM2946N ASPC128 27.735 1.825 13.472 1.0022.69NATOM2947CA ASPC 128 27.111 2.204 12.181 1.0022.93C
ATOM2948CB ASPC 128 26.481 3.593 12.236 1.0022.23C
ATOM2949CG ASPC 128 25.264 3.673 13.176 1.00 25.40C
ATOM2950ODl ASPC128 24.612 2.636 13.496 1.0024.21O
ATOM2951OD2ASPC 128 24.955 4.812 13.625 1.0027.49O
ATOM2952C ASPC 128 28.038 2.095 10.995 1.0023.69C
ATOM2953O ASPC128 27.664 1.493 10.008 1.0024.72O·ATOM2954N TYR C129 29.278 2.613 11.072 1.0024.34N
ATOM2955CA TYRC 129 30.097 2.618 9.855 1.00 23.26C
ATOM2956CB TYRC 129 31.008 3.870 9.724 1.00 22.30C
ATOM2957CG TYRC 129 30.161 5.086 9.432 1.00 21.55C
ATOM2958CDl TYRC 129 29.484 5.751 10.468 1.0022.48C
ATOM2959CEl TYR C 129 28.664 6.833 10.210 1.0020.10C
ATOM2960CZ TYRC 129 28.503 7.265 8.889 1.0017.89C
ATOM2961OH TYRC 129 27.707 8.339 8.625 1.0019.10O
ATOM2962CE2TYRC 129 29.175 6.680 7.866 1.0016.37C
ATOM2963CDZTYR C129 29.976 5.543 8.123 1.0018.94C
ATOM2964C TYRC 129 30.779 1.305 9.540 1.0023.97C
ATOM2965O TYRC 129 31.016 1.018 8.353 1.0025.45O
ATOM2966N HIS C 130 31.040 0.483 10.563 1.0022.82N
ATOM2967CA HIS C 130 31.575 -0.840 10.324 1.00 22.18C
ATOM2968CB HIS C130 32.122 -1.508 11.613 1.00 22.34C
ATOM2969CG HISC 130 33.423 -0.920 12.132 1.0022.80C
ATOM2970NDl HIS C 130 34.644 -1.117 11.515 1.0023.05N
ATOM2971CEl HIS C 130 35.593 -0.488 12.192 1.00 24.36C
ATOM2972NE2HISC 130 35.037 0.099 13.235 1.0025.02N
ATOM2973CD2HISC 130 33.683 -0.169 13.226 1.00 23.33C
ATOM2974C HISC 130 30.432 -1.683 9.689 1.00 22.10C
ATOM2975O HIS C 130 30.691 -2.610 8.966 1.00 22.84O
ATOM2976N ARGC131 29.188 -1.376 10.014 1.0022.77N
ATOM2977CA ARGC 131 27.992 -2.054 9.452 1.0023.66C
ATOM2978CB ARGC 131 26.757 -1.674 10.278 1.0024.16C
ATOM2979CG ARGC 131 25.416 -2.240 9.760 1.0021.83C
ATOM2980CD ARGC 131 24.288 -2.164 10.821 1.00 22.19C
ATOM2981NE ARGC 131 23.990 -0.798 11.312 1.00 20.93N
ATOM2982CZ ARGC 131 23.168 0.087 10.757 1.0020.94C
ATOM2983NHl ARGC 131 22.449 -0.204 9.655 1.0024.63N
ATOM2984NII2ARGC 131 23.043 1.271 11.322 1.0016.62N
ATOM2985C ARGC131 27.783 -1.628 8.011 1.0024.70C
ATOM2986O ARGC131 27.274 -2.410 7.205 1.0027.78O
ATOM2987N TYRC 132 28.163 -0.395 7.663 1.0024.82N
ATOM2988CA TYRC 132 28.036 0.039 6.278 1.00 24.48C
ATOM2989CB TYRC 132 28.090 1.565 6.148 1.00 23.38C
[0309]ATOM2990CG TYRC 132 27.0152.2416.951 1.0021.72 CATOM2991CDl TYRC13227.2703.4367.593 1.0018.57C
ATOM2992CEl TYR C 13226.3014.0498.3601.00 22.31C
ATOM2993CZ TYRC13225.0373.4948.491 1.0021.19 C
ATOM2994OH TYRC 132 24.107 4.1649.257 1.0019.88 O
ATOM2995CE2TYRC 13224.7342.3007.8641.0021.27C
ATOM2996CD2TYRC 13225.7321.6617.1011.00 21.63C
ATOM2997C TYRC 13229.026-0.6755.3891.00 25.78C
ATOM2998O TYRC 13228.694-1.0604.2511.0026.53O
ATOM2999N LEUC 13330.235-0.8735.9071.00 27.20N
ATOM3000CA LEUC 13331.224-1.7835.304 1.00 27.97 C
ATOM3001CB LEU C13332.474-1.8136.153 1.0027.74C
ATOM3002CG LEUC 13333.240-0.4986.255 1.00 27.95 C
ATOM3003CDl LEUC 13334.413-0.6537.2311.00 28.36C
ATOM3004CD2LEUC 13333.708-0.0614.8431.00 29.23C
ATOM3005C LEUC 13330.696-3.2065.1791.0029.11C
ATOM3006O LEU C13330.756-3.8174.0911.00 29.11O
ATOM3007N ALAC 13430.180-3.7326.2921.00 29.72N
ATOM3008CA ALAC 134 29.572-5.0666.329 1.0030.19C
ATOM3009CB ALAC13429.114-5.4077.754 1.00 30.80C
ATOM3010C ALAC 13428.432-5.2615.3281.0030.25C
ATOM3011O ALAC 13428.117-6.3884.9311.0031.54O
ATOM3012N GLUC 13527.815-4.1804.8911.00 30.67N
ATOM3013CA GLU C135 26.813-4.3043.826 1.00 30.35 C
ATOM3014CB GLU C13526.055-3.0113.684 1.0029.34C
ATOM3015CG GLU C135 25.267-2.7184.904 1.00 28.93 C
ATOM3016CD GLUC 135 24.555-1.4364.756 1.0025.41 C
ATOM3017OEl GLUC 13523.549-1.1755.4501.0026.25O
ATOM3018OE2GLUC 13525.004-0.6883.9001.0024.34O
ATOM3019C GLUC 13527.396-4.7162.4831.00 30.46C
ATOM3020O GLUC 13526.705-5.3471.6701.00 29.83O
ATOM3021N PHEC 13628.660-4.3752.2401.00 30.95N
ATOM3022CA PHEC13629.267-4.6390.9031.0031.96C
ATOM3023CB PHEC 13629.417-3.3540.0411.00 30.88C
ATOM3024CG PHEC 13630.494-2.4000.5091.0029.94C
ATOM3025CDl PHEC 13630.233-1.4621.4781.0027.00C
ATOM3026CEl PHE C13631.209-0.6021.9041.0026.34C
ATOM3027CZ PHEC 13632.460-0.6481.3261.0026.41C
ATOM3028CE2 PIIE C13632.732-1.5380.3591.0026.33C
ATOM3029CD2PHEC 13631.749-2.417-0.0631.0028.95C
ATOM3030C PHEC 13630.537-5.4800.8941.00 33.20C
ATOM3031O PHEC 13630.754-6.246-0.0611.00 33.46O
ATOM3032N LYS C13731.384-5.3331.9291.00 34.24N
ATOM3033CA LYSC 13732.568-6.1882.0531.0035.53C
[0310]ATOM3034CB LYS C137 33.387 -5.8443.307 1.00 34.61CATOM3035CG LYS C 137 33.897 -4.4193.353 1.00 30.24C
ATOM3036CD LYSC 137 34.764 -4.0472.168 1.00 29.05C
ATOM3037CE LYS C137 35.667 -2.8452.488 1.00 28.30C
ATOM3038NZ LYSC 137 36.530 -2.4291.325 1.0028.34N
ATOM3039C LYSC 137 32.122 -7.6732.017 1.00 37.30C
ATOM3040O LYS C137 30.943 -7.9792.310 1.0037.83O
ATOM3041N THRC 138 33.020 -8.5761.582 1.00 39.80N
ATOM3042CA THRC 138 32.638-10.0151.392 1.0041.71C
ATOM3043CB THRC 138 32.521 -10.438-0.093 1.0041.58C
ATOM3044OGl THRC138 33.801 -10.346-0.727 1.0041.08O
ATOM3045CG2THRC 138 31.521 -9.559-0.819 1.0042.30C
ATOM3046C THRC138 33.437-11.1092.141 1.00 43.09C
ATOM3047O THRC 138 32.898-12.2172.406 1.0043.70O
ATOM3048N GLYC139 34.685-10.8342.496 1.0043.30N
ATOM3049CA GLYC 139 35.500-11.9622.943 1.0045.00C
ATOM3050C GLYC 139 36.095-11.8264.312 1.00 45.38C
ATOM3051O GLYC139 35.396-11.9395.311 1.00 45.82O
ATOM3052N ALAC140 37.404-11.5924.341 1.0046.26N
ATOM3053CA ALAC 140 38.117-11.3395.585 1.0046.73C
ATOM3054CB ALAC140 39.632-11.3195.344 1.0046.80C
ATOM3055C ALAC140 37.642-10.0196.186 1.0046.83C
ATOM3056O ALAC 140 37.563 -9.8817.409 1.0046.88O
ATOM3057N GLU C 141 37.302 -9.0525.329 1.00 47.08N
ATOM3058CA GLUC 141 36.917 -7.7205.829 1.00 46.62C
ATOM3059CB GLUC 141 37.415 -6.6184.910 1.0046.84C
ATOM3060CG GLUC 141 37.254 -6.9463.462 1.0048.91C
ATOM3061CD GLUC 141 38.288 -6.2682.601 1.00 50.60C
ATOM3062OEl GLUC 141 38.740 -6.9061.638 1.00 53.05O
ATOM3063OE2GLUC 141 38.649 -5.1082.872 1.00 51.64O
ATOM3064C GLU C141 35.436 -7.5496.196 1.00 45.79C
ATOM3065O GLU C141 35.105 -6.6746.982 1.0045.64O
ATOM3066N ARG C142 34.563 -8.3875.647 1.00 45.51N
ATOM3067CA ARGC 142 33.174 -8.4826.114 1.00 45.95C
ATOM3068CB ARGC 142 32.349 -9.3965.169 1.0046.34C
ATOM3069CG ARGC 142 31.020 -9.9505.703 1.00 47.50C
ATOM3070CD ARG C142 29.743 -9.3015.143 1.00 50.73C
ATOM3071NE ARGC 142 28.505 -9.9415.659 1.00 52.42N
ATOM3072CZ ARG C 142 27.245 -9.4865.504 1.00 55.56C
ATOM3073NHl ARG C 142 26.234-10.1746.027 1.00 54.51N
ATOM3074NH2ARGC142 26.961 -8.3564.836 1.00 55.47N
ATOM3075C ARGC142 33.219 -8.9947.561 1.0045.78C
ATOM3076O ARG C142 32.655 -8.3748.479 1.00 45.22O
ATOM3077N LYS C 143 33.940-10.1087.726 1.0046.00N
[0311]ATOM3078CA LYS C143 34.297-10.736 8.998 1.0046.07CATOM3079CB LYS C 143 35.390-11.800 8.748 1.0047.02C
ATOM3080CG LYS C143 35.507-12.989 9.749 1.0048.77C
ATOM3081CD LYS C 143 36.433 -12.707 10.958 1.0051.48C
ATOM3082CE LYS C 143 36.541 -13.933 11.939 1.0051.22C
ATOM3083NZ LYS C 143 37.852-14.714 11.884 1.00 51.26N
ATOM3084C LYS C 143 34.760 -9.737 10.055 1.0045.52C
ATOM3085O LYS C 143 34.237 -9.744 11.172 1.0045.91O·ATOM3086N GLUC144 35.729 -8.886 9.713 1.00 44.37N
ATOM3087CA GLUC 144 36.303 -7.965 10.692 1.0043.62C
ATOM3088CB GLU C144 37.634 -7.417 10.223 1.0044.17C
ATOM3089CG GLUC 144 38.611 -8.405 9.665 1.00 45.92C
ATOM3090CD GLU C 144 39.645 -7.681 8.819 1.00 50.60C
ATOM3091OEl GLUC144 39.811 -8.016 7.598 1.0048.96O
ATOM3092OE2 GLUC144 40.262 -6.738 9.395 1.00 52.10O
ATOM3093C GLUC144 35.405 -6.768 10.924 1.00 42.63C
ATOM3094O GLU C144 35.458 -6.138 11.992 1.0042.41O
ATOM3095N ALAC 145 34.611 -6.428 9.909 1.0040.63N
ATOM3096CA ALAC 145 33.668 -5.320 10.026 1.00 38.98C
ATOM3097CB ALAC145 33.272 -4.803 8.628 1.00 38.71C
ATOM3098C ALAC 145 32.441 -5.732 10.857 1.00 37.76C
ATOM3099O ALAC145 31.950 -4.970 11.660 1.0037.21O
ATOM3100N ALAC146 31.964 -6.953 10.679 1.00 37.52N
ATOM3101CA ALAC 146 30.891 -7.480 11.520 1.00 37.50C
ATOM3102CB ALAC 146 30.454 -8.821 11.015 1.00 37.00C
ATOM3103C ALAC 146 31.318 -7.576 12.998 1.00 38.10C
ATOM3104O ALAC146 30.540 -7.251 13.906 1.00 37.99O
ATOM3105N GLUC 147 32.550 -8.030 13.221 1.00 38.13N
ATOM3106CA GLU C 147 33.113 -8.168 14.564 1.00 39.42C
ATOM3107CB GLUC 147 34.431 -8.980 14.550 1.00 39.08C
ATOM3108CG GLUC 147 34.218-10.522 14.598 1.0042.01C
ATOM3109CD GLUC 147 35.519-11.358 14.563 1.0042.30C
ATOM3110OEl GLUC 147 36.367-11.131 13.668 1.00 45.45O
ATOM3111OE2 GLU C147 35.684 -12.272 15.420 1.00 47.21O
ATOM3112C GLU C147 33.306 -6.819 15.245 1.00 38.22C
ATOM3113O GLU C147 32.994 -6.665 16.436 1.00 39.30O
ATOM3114N SERC 148 33.780 -5.831 14.494 1.00 37.03N
ATOM3115CA SERC148 33.944 -4.488 15.045 1.00 35.28C
ATOM3116CB SERC 148 34.738 -3.636 14.093 1.00 35.70C
ATOM3117OG SERC148 35.849 -4.366 13.632 1.00 36.51O
ATOM3118C SERC 148 32.626 -3.806 15.378 1.0034.22C
ATOM3119O SERC 148 32.572 -2.980 16.297 1.00 33.75O
ATOM3120N THRC 149 31.574 -4.149 14.625 1.00 33.10N
ATOM3121CA THRC 149 30.234 -3.585 14.807 1.00 31.31C
[0312]ATOM3122CB THRC149 29.242-3.98613.6881.0031.05CΑΓΟΜ3123OGl THRC 149 29.750-3.61612.4101.0029.00O
ATOM3124CG2 THRC 149 27.920-3.28413.8871.0030.18C
ATOM3125C THRC 149 29.664-4.10716.0951.0031.27C
ATOM3126O THRC 149 29.072-3.35016.8461.0031.83O
ATOM3127N METC 150 29.848-5.40316.3371.0031.44N
ATOM3128CA METC150 29.510-6.032 17.6171.00 31.81C
ATOM3129CB METC150 29.804-7.539 17.5621.0031.65C·ATOM3130CG METC150 29.109-8.398 18.6371.00 32.55C
ATOM3131SD METC 150 27.309-8.34118.6471.00 34.20S
ATOM3132CE METC 150 26.999-9.60917.4021.0031.36C
ATOM3133C METC 150 30.245-5.35918.7721.0031.20C
ATOM3134O METC 150 29.605-4.83319.6821.0031.62O
ATOM3135N VALC 151 31.573-5.31918.7151.00 30.86N
ATOM3136CA VALC151 32.375-4.69819.8141.0031.09C
ATOM3137CB VALC151 33.898-4.67819.4751.00 30.65C
ATOM3138CGl VALC 151 34.731-3.99120.5711.0031.39C
ATOM3139CG2VALC 151 34.396-6.10019.2491.00 30.68C
ATOM3140C VALC 151 31.838-3.31020.2191.00 30.63C
ATOM3141O VALC 151 31.573-3.04921.4021.00 30.81O
ATOM3142N ALAC 152 31.608-2.46519.2061.00 30.61N
ATOM3143CA ALAC152 31.204-1.06919.3651.00 29.50C
ATOM3144CB ALAC 152 31.400-0.33118.0401.00 30.16C
ATOM3145C ALAC 152 29.773-0.94419.8291.00 29.54C
ATOM3146O ALAC 152 29.498-0.16220.7411.00 28.10O
ATOM3147N TYRC 153 28.854-1.70719.1911.00 29.47N
ATOM3148CA TYRC 153 27.461-1.75619.6161.0029.49C
ATOM3149CB TYRC153 26.584-2.60518.6521.0029.92C
ATOM3150CG TYRC153 26.128-1.85717.3851.0029.49C
ATOM3151CDl TYR C 153 26.191-0.45317.3071.00 28.37C
ATOM3152CEl TYRC 153 25.7880.25016.1581.0026.65C
ATOM3153CZ TYRC153 25.288-0.45815.0751.0028.68C
ATOM3154OH TYRC153 24.9040.228 13.9471.00 28.93O
ATOM3155CE2TYRC 153 25.197-1.84615.1231.00 29.13C
ATOM3156CD2TYRC 153 25.612-2.54716.2801.00 30.63C
ATOM3157C TYRC 153 27.318-2.20721.0661.00 30.36C
ATOM3158O TYRC 153 26.686-1.50721.8801.0031.10O
ATOM3159N LYSC 154 27.930-3.35521.3841.0031.47N
ATOM3160CA LYSC 154 28.065-3.87622.7571.00 32.29C
ATOM3161CB LYSC 154 28.967-5.12322.7781.00 32.64C
ATOM3162CG LYS C 154 28.257-6.44423.0761.0037.11C
ATOM3163CD LYS C 154 28.893-7.62422.2941.0042.12C
ATOM3164CE LYSC 154 30.426-7.81522.5621.00 45.01C
ATOM3165NZ LYSC 154 31.146-8.62621.4701.00 42.49N
[0313]ATOM3166C LYSC 154 28.622 -2.828 23.721 1.0031.81CATOM3167O LYS C 154 27.978 -2.529 24.734 1.0031.85O
ATOM3168N ALAC 155 29.792 -2.263 23.418 1.0031.07N
ATOM3169CA ALAC 155 30.411 -1.295 24.345 1.0031.04C
ATOM3170CB ALAC 155 31.744 -0.784 23.821 1.0031.46C
ATOM3171C ALAC 155 29.472 -0.139 24.572 1.0031.15C
ATOM3172O ALAC 155 29.188 0.237 25.720 1.0031.15O
ATOM3173N ALAC156 28.940 0.409 23.477 1.0031.29N
ATOM3174CA ALAC 156 27.899 1.438 23.595 1.00 30.68C
ATOM3175CB ALAC 156 27.507 1.951 22.238 1.0030.83C
ATOM3176C ALAC 156 26.668 0.962 24.383 1.00 30.96C
ATOM3177O ALAC156 26.043 1.749 25.096 1.00 29.99O
ATOM3178N GLNC 157 26.301 -0.317 24.244 1.00 32.01N
ATOM3179CA GLNC 157 25.122 -0.829 24.942 1.00 33.29C
ATOM3180CB GLNC 157 24.740 -2.224 24.461 1.00 32.90C
ATOM3181CG GLNC 157 23.392 -2.696 24.995 1.00 33.21C
ATOM3182CD GLNC 157 23.054 -4.130 24.595 1.00 33.73C
ATOM3183OEl GLNC 157 23.810 -5.067 24.879 1.0034.10O
ATOM3184NE2GLNC157 21.915 -4.303 23.920 1.00 36.39N
ATOM3185C GLNC157 25.341 -0.862 26.446 1.00 33.88C
ATOM3186O GLNC 157 24.457 -0.514 27.226 1.0033.18O
ATOM3187N ASPC 158 26.520 -1.306 26.851 1.00 35.57N
ATOM3188CA ASPC 158 26.849 -1.345 28.283 1.00 36.84C
ATOM3189CB ASPC158 28.266 -1.857 28.482 1.0037.12C
ATOM3190CG ASPC158 28.384 -3.313 28.128 1.00 38.93C
ATOM3191ODl ASPC 158 29.515 -3.821 27.941 1.00 43.18O
ATOM3192OD2ASPC 158 27.319 -3.949 28.022 1.00 42.00O
ATOM3193C ASPC158 26.607 -0.011 28.984 1.00 37.00C
ATOM3194O ASPC 158 25.939 0.031 30.018 1.00 37.58O
ATOM3195N ILEC 159 27.099 1.071 28.377 1.00 37.06N
ATOM3196CA ILEC 159 26.943 2.427 28.906 1.0036.64C
ATOM3197CB ILE C 159 27.870 3.428 28.145 1.00 36.65C
ATOM3198CGl ILEC 159 29.337 2.978 28.268 1.00 36.56C
ATOM3199CDl ILEC 159 30.283 3.505 27.196 1.00 35.87C
ATOM3200CG2ILEC 159 27.661 4.863 28.632 1.00 34.70C
ATOM3201C ILEC 159 25.490 2.903 28.872 1.00 37.20C
ATOM3202O ILEC 159 25.010 3.514 29.835 1.00 36.93O
ATOM3203N ALAC160 24.807 2.644 27.755 1.00 37.46N
ATOM3204CA ALAC160 23.422 3.097 27.567 1.00 37.76C
ATOM3205CB ALAC 160 22.881 2.693 26.173 1.00 37.28C
ATOM3206C ALAC 160 22.530 2.551 28.667 1.0037.86C
ATOM3207O ALAC160 21.810 3.310 29.295 1.00 38.98O
ATOM3208N LEU C161 22.587 1.239 28.894 1.0038.31N
ATOM3209CA LEU C 161 21.816 0.581 29.963 1.00 38.42C
[0314]ATOM3210CB LEUC 16122.006-0.944 29.8971.00 38.18CATOM3211CG LEUC16121.030Λ 111 29.0281.00 38.30C
ATOM3212CDl LEU C16120.611-1.091 27.7501.00 38.48C
ATOM3213CD2 LEU C16121.639-3.129 28.6831.00 38.42C
ATOM3214C LEU C16122.1321.127 31.3621.00 38.55C ATOM3215O LEU C16121.2201.485 32.1251.00 38.43O
ATOM3216N ALAC16223.4241.228 31.6821.00 39.21N
ATOM3217CA ALAC16223.844 1.721 32.9971.0039.54C
ATOM3218CB ALAC 16225.358 1.560 33.1911.00 39.10C
ATOM3219C ALAC 16223.3963.163 33.2161.00 39.73C
ATOM3220O ALAC16222.8453.491 34.2561.0040.39O
ATOM3221N ASPC 16323.5594.008 32.2061.00 40.07N
ATOM3222CA ASPC 16323.5915.453 32.4391.00 39.91C
ATOM3223CB ASPC 16324.9626.002 32.0061.0040.44C
ATOM3224CG ASPC 16326.1105.437 32.8531.00 43.11C
ATOM3225ODl ASPC 16325.8945.263 34.0821.00 45.21O
ATOM3226OD2ASPC16327.2195.166 32.3051.00 45.03O
ATOM3227C ASPC 16322.4546.278 31.8371.00 39.51C
ATOM3228O ASPC 16322.2017.385 32.3041.0040.06O
ATOM3229N LEUC 16421.7695.759 30.8171.0038.40N
ATOM3230CA LEU C16420.770 6.559 30.1091.00 37.59C
ATOM3231CB LEUC 16421.053 6.666 28.5901.00 37.34C
ATOM3232CG LEUC16422.362 7.187 27.9501.00 36.93C
ATOM3233CDl LEU C16422.1327.497 26.4521.00 35.61C
ATOM3234CD2LEUC16422.9338.418 28.6201.00 33.26C
ATOM3235C LEUC 16419.3856.006 30.3401.00 37.13C
ATOM3236O LEU C16419.1974.792 30.4091.00 36.71O
ATOM3237N ALA C16518.4316.916 30.4641.0036.52N
ATOM3238CA ALAC16517.027 6.584 30.5981.00 36.78C
ATOM3239CB ALAC16516.228 7.895 30.6901.00 36.73C
ATOM3240C ALAC16516.5775.740 29.3851.00 36.37C
ATOM3241O ALAC16517.0495.993 28.2871.00 35.46O
ATOM3242N PRO C16615.6864.724 29.5861.00 36.78N
ATOM3243CA PRO C16615.227 3.836 28.4841.00 36.63C
ATOM3244CB PROC 16614.202 2.906 29.1601.00 36.88C
ATOM3245CG PROC16613.807 3.602 30.3861.00 37.30C
ATOM3246CD PROC16615.050 4.336 30.8571.00 37.05C
ATOM3247C PROC16614.5594.583 27.3671.0036.01C
ATOM3248O PRO C16614.4014.055 26.2681.00 36.86O
ATOM3249N THRC 16714.1785.815 27.6691.00 35.84N
ATOM3250CA THRC16713.417 6.677 26.7861.00 34.84C
ATOM3251CB THRC16712.513 7.598 27.6021.00 35.73C
ATOM3252OGl THR C 16713.293 8.214 28.6431.0035.83O
ATOM3253CG2THRC16711.3186.801 28.2091.00 35.92C
[0315]CN 102947445 A书明说96/376 页ATOM3254CTHRC 16714.3307.57325.9741.00 34.50CATOM3255OTHRC 16713.8568.28525.0801.00 34.05OATOM3256NHIS C 16815.6317.54126.2941.00 33.15NATOM3257CAHISC 16816.6048.44725.6921.00 32.16CATOM3258CBHIS C16817.9278.44926.4811.00 31.84CATOM3259CGHISC 16818.8479.58226.1241.00 35.23CATOM3260NDl HIS C 16819.4939.66924.9071.00 35.79NATOM3261CEl HIS C 16820.24410.76024.8801.00 36.07CATOM3262NE2HISC 16820.09811.39426.0301.00 36.52NATOM32.63CD2HISC 16819.25010.66826.8371.00 37.22CATOM3264CHIS C16816.8388.11124.2181.00 30.42C ATOM3265OHISC 16817.2396.98523.9001.00 30.38OATOM3266NPROC 16916.5929.09523.3181.0029.42NATOM3267CAPRO C 16916.7228.93421.8801.0028.92CATOM3268CBPROC 16916.73110.38421.3771.0029.12CATOM3269CGPRO C 16915.86211.08022.3231.0028.99CATOM3270CDPROC 16916.12510.45723.6581.00 29.22CATOM3271CPROC 16918.0018.22821.4601.0028.80CATOM3272OPRO C 16917.9627.37020.5791.0028.62OATOM3273NILEC 17019.1258.59222.0771.00 27.72NATOM3274CAILE C 17020.4128.00021.7391.0027.31CATOM3275CBILEC 17021.6028.86022.3171.0027.49CATOM3276CGl ILEC 17021.57610.29521.7481.00 27.07CATOM3277CDl ILE C 17022.71711.21622.2561.0026.37CATOM3278CG2ILEC 17022.9398.13722.1271.00 27.76CATOM3279CILEC 17020.5186.55322.2281.00 27.24CATOM3280OILEC 17021.1795.72221.5951.00 28.21OATOM3281NARGC 17119.9096.25023.3731.00 26.79NATOM3282CAARGC 17119.8174.85723.8201.00 26.58CATOM3283CBARG C 17119.3074.76625.2721.00 26.77CATOM3284CGARGC 17118.9233.33025.6951.00 24.53CATOM3285CDARGC 17118.6813.21327.1581.00 23.68CATOM3286NEARGC 17118.2241.87627.5091.00 27.13NATOM3287CZARG C 17118.0061.43528.7611.00 29.80CATOM3288NHl ARG C 17118.2642.20629.8141.00 27.03NATOM3289NH2ARGC17117.5540.20328.9681.00 25.35NATOM3290CARGC 17118.8524.08122.9021.0026.60CATOM3291OARG C 17119.1312.95922.5181.00 25.43OATOM3292NLEU C 17217.7104.69222.5971.0027.31NATOM3293CALEUC 17216.7194.10221.6541.00 28.45CATOM3294CBLEU C 17215.4854.98121.5721.00 28.14CATOM3295CGLEUC 17214.5034.92022.7431.00 29.19CATOM3296CDl LEU C 17213.2405.72922.4101.0026.15CATOM3297CD2LEUC17214.1563.45823.0451.0028.38C[0316]100ATOM3298CLEUC 17217.2773.90720.2571.00 28.78CATOM3299OLEU C 17216.9652.92519.6221.00 30.20OATOM3300NGLYC 17318.1304.83819.8071.00 29.69NATOM3301CAGLYC 17318.7454.80718.4671.00 29.00CATOM3302CGLYC 17319.8123.73418.3431.0028.71CATOM3303OGLYC 17319.9703.13117.3011.00 29.51OATOM3304NLEUC 17420.5223.47019.4351.0027.88NATOM3305CALEU C 17421.4472.37319.4681.0026.83CATOM3306CBLEU C 17422.2922.43220.7541.0026.85CATOM3307CGLEU C 17423.1371.19121.0411.0025.06CATOM3308CDl LEUC 17424.1821.00419.9931.0022.61CATOM3309CD2LEUC 17423.7831.35022.4371.0028.37CATOM3310CLEUC 17420.7721.01819.3841.0026.46CATOM3311OLEUC 17421.3220.09518.8311.00 27.64OATOM3312NALAC 17519.6070.88919.9921.0025.63NATOM3313CAALAC 17518.921-0.38720.0981.0025.53CATOM3314CBALAC 17517.828-0.28421.2221.0024.05CATOM3315CALAC 17518.319-0.73618.7211.00 24.65CATOM3316OALAC 17518.455-1.85018.2231.00 26.65OATOM3317NLEUC 17617.6730.24518.1141.00 24.27NATOM3318CALEUC 17617.3070.22816.6951.0023.43CATOM3319CBLEUC 17616.7681.60116.2871.0022.59CATOM3320CGLEUC 17616.2091.82414.8771.0022.70CATOM3321CDl LEUC 17615.0360.86514.5031.0023.00CATOM3322CD2 LEUC 17615.7953.25714.7311.00 20.49CATOM3323CLEUC 17618.452-0.17515.7781.00 24.50CATOM3324OLEUC 17618.301-1.07014.9601.0025.08OATOM3325NASNC 17719.6170.48215.8941.00 25.55NATOM3326CAASNC 17720.6850.18014.9581.0024.75CATOM3327CBASN C 17721.6621.34814.9021.00 26.59CATOM3328CGASN C 17721.1382.45114.0261.0026.74CATOM3329ODl ASN C 17719.9592.43313.6511.0028.01OATOM3330ND2ASNC 17722.0003.39613.6651.0026.35NATOM3331CASNC 17721.320-1.16015.2241.00 24.11CATOM3332OASNC 17721.679-1.92414.3021.0025.19OATOM3333NPHEC 17821.370-1.49516.4981.0022.98NATOM3334CAPHEC 17821.873-2.79016.9131.0023.06CATOM3335CBPHEC 17821.973-2.81118.4271.00 22.32CATOM3336CGPHHC 17822.982-3.78618.9771.0024.13CATOM3337CDl PHEC 17823.459-4.84018.2331.00 23.51CATOM3338CEl PHE C 17824.402-5.72018.7801.0024.35CATOM3339CZPHEC 17824.811-5.57420.0961.00 22.95CATOM3340CE2 PHE C 17824.327-4.55220.8421.00 22.56CATOM3341CD2PHEC 17823.418-3.65920.2971.00 24.37C[0317]ATOM3342CPHEC 17820.947-3.92916.4311.00 22.37CATOM3343OPHEC 17821.420-4.96915.9881.00 21.90OATOM3344NSERC 17919.640-3.75116.5521.0022.95NATOM3345CASERC 17918.742-4.85116.1501.0024.78CATOM3346CBSERC 17917.295-4.65716.6351.00 23.53CATOM3347OGSERC 17916.726-3.45916.1741.0025.16OATOM3348CSERC 17918.864-5.06914.6641.00 25.33CATOM3349OSERC 17919.000-6.18314.2521.00 27.55OATOM3350NVALC 18018.920-3.98313.8861.00 27.05NATOM3351CAVALC 18019.062-4.00212.4141.0026.95CATOM3352CBVALC 18018.855-2.54611.8131.00 27.26CATOM3353CGl VALC 18019.280-2.421]0.3391.00 26.67CATOM3354CG2VALC 18017.413-2.10011.9901.00 26.01CATOM3355CVALC 18020.353-4.70711.9501.00 27.82CATOM3356OVALC 18020.327-5.45910.9731.0028.33OATOM3357NPHEC 18121.466-4.46912.6571.00 29.05NATOM3358CAPHEC 18122.702-5.24412.4961.0029.33CATOM3359CBPHEC 18123.798-4.75113.4651.00 29.52CATOM3360CGPHEC 18124.979-5.68213.5771.00 29.20CATOM3361CDl PHEC 18125.817-5.90512.4871.00 29.53CATOM3362CEl PHEC 18126.920-6.75812.5821.00 28.17CATOM3363CZPIffiC 18127.177-7.40313.7771.00 29.76CATOM3364CE2PHEC 18126.360-7.16614.8911.0029.58CATOM3365CD2PHEC 18125.268-6.31914.7821.00 29.55CATOM3366CPHEC 18122.481-6.75112.6541.0029.45CATOM3367OPHEC 18123.005-7.53011.8601.00 29.15OATOM3368NTYRC 18221.713-7.14813.6701.00 30.67NATOM3369CATYRC 18221.270-8.56213.8471.00 31.34CATOM3370CBTYR C 18220.521-8.80215.1861.0031.18CATOM3371CGTYRC 18221.408-8.96216.4341.00 31.63CATOM3372CDl TYR C 18222.350-9.99616.5341.00 31.23CATOM3373CEl TYRC 18223.155-10.14217.6581.00 30.27CATOM3374CZTYRC 18223.003-9.26618.7171.00 31.45CATOM3375OHTYRC 18223.761-9.39319.8501.0031.29OATOM3376CE2TYRC 18222.070-8.24618.6511.00 33.26CΑΓΟΜ3377CD2TYRC 18221.275-8.10017.5051.00 29.12CATOM3378CTYRC 18220.406-9.08112.6931.00 31.50CATOM3379OTYRC 18220.688 -10.13712.1531.00 31.08OATOM3380NTYRC 18319.366-8.35312.3201.00 32.35NATOM3381CATYRC 18318.481-8.82011.2221.00 34.45CATOM3382CBTYRC 18317.296-7.90211.0211.00 34.99CATOM3383CGTYRC 18316.163-8.62410.3681.00 37.05CATOM3384CDl TYRC 18315.390-9.49011.1131.00 37.59CATOM3385CEl TYRC 18314.340-10.17110.5661.00 39.27C[0318]CN 102947445 A书明说99/376 页ATOM3386CZTYRC 18314.032-10.0169.2381.00 38.88CATOM3387OHTYRC 18312.955-10.7418.7831.00 38.87OATOM3388CE2TYRC 18314.788-9.1488.4261.00 39.43CATOM3389CD2TYRC18315.862-8.4509.0121.00 37.27CATOM3390CTYRC 18319.151-9.0109.8651.00 34.63CATOM3391OTYRC 18319.114-■10.0819.3031.00 34.95OATOM3392NGLUC 18419.792-7.9599.3741.00 35.53NATOM3393CAGLUC 18420.246-7.8847.9971.00 35.65CATOM3394CBGLUC 18420.244-6.4137.5501.00 36.80CATOM3395CGGLUC 18419.000-5.6477.9751.0040.92CATOM3396CDGLUC 18417.944-5.5816.8891.00 46.06C·ATOM3397OEl GLUC 18417.945-6.4355.9591.0046.09OATOM3398OE2GLUC18417.116-4.6466.9751.0048.79OATOM3399CGLU C 18421.645-8.4117.8361.00 34.53CATOM3400OGLU C 18421.932-9.1196.8721.0033.99OATOM3401NILEC 18522.524-8.0258.7611.00 32.90NATOM3402CAILEC 18523.916-8.4378.6811.00 32.07CATOM3403CBILEC 18524.901-7.4629.4431.00 31.85CATOM3404CGl ILE C 18524.887-6.0318.8671.00 31.29CATOM3405CDl ILE C 18525.016-5.9377.3091.00 31.73CATOM3406CG2ILEC 18526.322-8.0139.3881.00 30.29CATOM3407CILEC 18524.148-9.8569.1981.00 32.08CATOM3408OILEC 18524.851 -10.6508.5841.00 32.33OATOM3409NLEUC 18623.608 -10.15710.3641.00 31.99NATOM3410CALEUC 18623.878-11.41811.0151.00 32.36CATOM3411CBLEUC 18624.023.-11.20012.5221.00 32.10CATOM3412CGLEUC 18625.454-11.05213.0751.0033.66CATOM3413CDl LEU C 18626.391 -10.38812.1181.00 30.23CATOM3414CD2LEUC18625.459 -10.36914.4421.00 31.96CATOM3415CLEUC 18622.777 -12.41610.7281.00 32.98CATOM3416OLEU C 18622.895 -13.58911.0871.00 33.56OATOM3417NASN C 18721.711 -11.95710.0821.00 33.40NATOM3418CAASNC 18720.585-12.8329.6961.0033.86CATOM3419CBASN C 18721.027-13.8548.6241.00 33.41CATOM3420CGASNC 18721.550-13.2007.3231.00 33.22CATOM3421ODl ASN C 18720.880 ■•12.3716.7031.00 29.18OATOM3422ND2ASNC18722.745 ■■13.6096.9051.00 32.87NATOM3423CASNC 18719.993 -13.56810.9101.00 34.71CATOM3424OASN C 18719.858-14.79210.8751.00 35.38OATOM3425NSERC 18819.663-12.81611.9691.00 35.12NATOM3426CASERC 18819.145-13.32313.2531.00 34.86CATOM3427CBSERC 18820.136--13.03514.3991.00 34.94CATOM3428OGSERC 18821.398-13.65814.2271.00 35.00OATOM3429CSERC 18817.855-12.57513.5961.00 35.08C[0319]103[0320]ATOM3430OSERC 18817.881 -11.67414.4361.00 35.34OΑΓΟΜ3431NPROC 18916.724-■12.93312.9591.00 35.44NATOM3432CAPRO C 18915.443-12.29913.2431.00 35.25CATOM3433CBPROC 18914.445-13.17912.4751.00 35.39CATOM3434CGPRO C 18915.200-13.70611.3621.00 36.14CATOM3435CDPROC 18916.573-13.98211.9311.00 35.61CATOM3436CPROC 18915.061 -12.27914.7231.00 34.68CATOM3437OPROC 18914.558-■11.28015.1961.00 34.86O ATOM3439CAASPC 19015.009-13.57416.8391.00 34.92CATOM3440CBASPC 19015.334-15.02317.2741.00 34.95CATOM3441CGASPC 19014.194-16.00016.9881.00 36.40CATOM3442ODl ASPC 19014.461 -17.13616.5211.00 35.84OATOM3443OD2ASPC19Q13.033-15.64117.2631.00 39.59OATOM3444CASPC 19015.808-12.61817.7171.00 34.01CATOM3445OASPC 19015.250-11.97218.5841.00 32.74OATOM3446NARGC 19117.120--12.57617.5281.0033.95NATOM3447CAARGC 19117.950-11.67918.3241.00 34.68CATOM3448CBARGC 19119.435-11.87918.0301.00 34.33CATOM3449CGARGC 19120.066-13.09418.7311.00 36.45CATOM3450CDARGC 19121.571-13.19718.4151.00 37.40CATOM3451NEARGC 19122.240-14.39018.9591.0044.84NATOM3452CZARGC 19123.574-14.56019.0171.0048.87CATOM3453NHl ARG C 19124.422-13.61618.5711.0047.74NATOM3454NH2ARGC 19124.079-15.68319.5391.00 49.27NATOM3455CARGC 19117.524-10.23918.0851.00 34.15CATOM3456OARGC 19117.447-9.46419.0441.00 34.74OATOM3457NALAC 19217.192-9.90716.8211.00 33.01NATOM3458CAALAC 19216.804-8.55316.4291.00 31.38CATOM3459CBALAC 19216.803-8.40814.9031.00 31.68CATOM3460CALAC 19215.474-8.11416.9971.00 30.93CATOM3461OALAC 19215.358-7.00717.5061.0029.53OATOM3462NCYS C 19314.446-8.96516.8571.0030.99NATOM3463CACYS C 19313.154-8.76317.5121.00 30.58CATOM3464CBCYS C 19312.196-9.88417.1191.00 30.91CATOM3465SGCYS C 19311.673-9.68715.4571.00 33.34SATOM3466CCYSC 19313.209-8.71819.0321.0029.93CATOM3467OCYS C 19312.478-7.97019.6331.0030.27OATOM3468NASNC 19414.011-9.57019.6491.00 30.16NATOM3469CAASNC 19414.117-9.58421.0971.00 31.73CATOM3470CBASN C 19414.914-10.80721.6091.00 32.20CATOM3471CGASNC 19414.166-12.17421.4201.00 36.09CATOM3472ODl ASN C 19414.825 -•13.24821.3611.00 39.44OATOM3473ND2ASNC19412.811-12.14521.3421.00 35.01N104CN 102947445 A书明说101/376 页ATOM3474CASNC 19414.733-8.26021.5751.00 31.29CATOM3475OASNC 19414.158-7.57222.4271.00 31.79OATOM3476NLEUC 19515.864-7.88220.9771.00 30.83NATOM3477CALEUC 19516.555-6.62121.3141.00 29.31CATOM3478CBLEUC 19517.844-6.47720.5031.00 29.62CATOM3479CGLEUC 19518.932-5.50821,0221.00 26.16CATOM3480CDl LEU C 19520.216-5.80920.3471.0024.55CATOM3481CD2LEUC19518.566-4.09120.7681.00 23.50CATOM3482CLEUC 19515.701-5.39621.0791.00 29.33CATOM3483OLEUC 19515.584-4.56221.9491.00 28.81O ATOM3484NALAC 19615.084-5.30719.8951.00 29.20NATOM3485CAALAC 19614.204-4.19319.5661.00 28.17CATOM3486CBALAC 19613.768-4.26618.1051.00 27.39CATOM3487CALAC 19612.993-4.13920.4761.00 28.33CATOM3488OALAC 19612.529-3.05520.8491.0028.16OATOM3489NLYS C 19712.459-5.30620.8231.0029.08NATOM3490CALYSC 19711.252-5.31521.6351.00 29.24CATOM3491CBLYSC 19710.430-6.59721.5091.0028.98CATOM3492CGLYS C 1978.983-6.23121.8021.0031.37CATOM3493CDLYSC 1978.140-7.36122.2741.0034.49CATOM3494CELYS C 1976.786-6.79322.7141.0033.24CATOM3495NZLYSC 1976.499-7.42724.0271.0034.52NATOM3496CLYSC 19711.500-4.99723.0861.00 28.33CATOM3497OLYS C 19710.715-4.28623.7111.00 28.76OATOM3498NGLNC 19812.561-5.54623.6491.00 28.78NATOM3499CAGLNC 19812.932-5.15425.0141.0029.24CATOM3500CBGLN C 19814.079-5.99325.5311.00 29.36CATOM3501CGGLNC 19813.590-7.40225.7961.00 31.43CATOM3502CDGLNC 19814.616-8.29526.4321.00 35.41CATOM3503OEl GLNC 19814.785-9.43725.9901.00 39.59OATOM3504NE2GLNC19815.296-7.80627.4871.00 34.19NATOM3505CGLNC 19813.180-3.66925.1901.0029.25CATOM3506OGLNC 19812.751-3.08726.1991.0029.57OATOM3507NALAC 19913.839-3.05424.2051.0029.30NATOM3508CAALAC 19914.101-1.60524.2231.00 30.14CATOM3509CBALAC 19915.051-1.21023.0821.00 30.42CATOM3510CALAC 19912.811-0.81724.1361.00 29.82CATOM3511OALAC 19912.5800.11024.8971.00 30.13OATOM3512NPHE C 20011.960-1.22723.2051.00 30.32NATOM3513CAPHE C 20010.643-0.65823.0671.00 30.16CATOM3514CBPHE C 2009.875-1.36621.9191.0029.97CATOM3515CGPHE C 2008.572-0.70621.5881.0029.32CATOM3516CDl PHE C 2008.5320.38120.7131.0029.43CATOM3517CEl PHE C 2007.3441.02220.4211.0028.21C[0321]105ATOM3518CZPHE C 2006.1600.56920.9991.00 30.24CATOM3519CE2 PHE C 2006.182-0.52921.8731.0028.12CATOM3520CD2 PHE C 2007.395-1.15122.1581.0029.80CATOM3521CPHE C 2009.860-0.73024.3921.00 29.50CATOM3522OPHE C 2009.2660.25624.8051.00 29.46OATOM3523NASP C 2019.866-1.90225.0321.0029.94NATOM3524CAASP C 2019.082-2.17126.2421.00 30.13CATOM3525CBASP C 2019.063-3.68826.5521.0029.77CATOM3526CGASP C 2018.102-4.49025.6131.00 31.37CATOM3527ODl ASP C 2017.298-3.84924.9251.00 32.64OATOM3528QD2ASPC2018.136-5.75925.5621.0029.40OATOM3529CASP C2019.603-1.32127.4211.00 30.84CATOM3530OASP C 2018.818-0.66128.1091.00 30.14OATOM3531NGLU C 20210.925-1.28927.6291.00 31.48NATOM3532CAGLU C 20211.491-0.44628.7131.0032.63CATOM3533CBGLU C 20213.010-0.59128.8291.00 33.30CATOM3534CGGLU C 20213.530-2.03329.0131.0035.65CATOM3535CDGLU C 20214.947-2.20828.4611.00 39.56CATOM3536OEl GLU C 20215.616-3.16628.9001.00 43.41OATOM3537OE2GLUC20215.400-1.39827.6081.00 38.24OATOM3538CGLU C 20211.1331.02628.5551.00 32.95CATOM3539OGLU C 20210.8531.68429.5511.00 32.80OATOM3540NALAC 20311.1141.54127.3111.00 33.40NATOM3541CAALAC 20310.7162.93227.0601.00 33.68CATOM3542CBALA C 20311.2203.40725.7021.00 33.79CATOM3543CALAC 2039.1983.17427.1881.00 34.19CATOM3544OALA C 2038.7534.25827.5801.00 34.21OATOM3545NILE C 2048.3972.18326.8331.00 34.98NATOM3546CAILE C 2046.9632.29827.0301.0035.93CATOM3547CBILE C 2046.2091.12826.3551.00 35.24CATOM3548CGl ILE C 2046.1931.34824.8401.00 33.37CATOM3549CDl ILE C 2045.4142.52124.3861.00 31.93CATOM3550CG2ILEC2044.8070.93326.9551.00 35.28CATOM3551CILE C 2046.6562.41528.5301.00 37.46CATOM3552OILE C 2045.8013.20128.9461.00 37.44OATOM3553NSER C 2057.3711.67229.3541.00 39.37NATOM3554CASER C 2057.1471.82230.7901.0041.50CATOM3555CBSER C 2057.9490.80931.6041.00 40.73CATOM3556OGSER C 2059.3141.16631.6391.00 44.08OATOM3557CSER C 2057.3643.25831.2841.0042.41CATOM3558OSER C 2056.6893.69132.2301.0043.13OATOM3559NGLU C 2068.2464.01830.6251.00 43.33NATOM3560CAGLU C 2068.5995.35331.1261.0044.18CATOM3561CBGLU C 20610.0945.44931.4101.0044.00C[0322]CN 102947445 A书明说103/376 页ATOM3562CGGLU C 20610.5454.58532.5621.0045.46CATOM3563CDGLU C 20611.9694.92133.0341.00 48.74CATOM3564OEl GLU C 20612.4856.01032.6731.0049.44OATOM3565OE2GLUC2Q612.5824.088O ·-» ^ l J-,. /1.0049.48OATOM3566CGLU C 2068.1366.55330.2991.0045.03CATOM3567OGLU C 2068.4007.69830.6881.0045.77OATOM3568NLEU C 2077.3976.30829.2161.00 45.21NATOM3569CALEU C 2077.0907.33928.2401.0045.65CATOM3570CBLEU C 2076.6346.66626.9311.00 45.72CATOM3571CGLEU C 2076.2927.49225.6791.0045.87C·ATOM3572CDl LEU C 2077.5048.30525.1811.00 44.57CATOM3573CD2LEUC2075.6606.62124.5671.0044.80CATOM3574CLEU C 2076.1138.45428.6871.00 46.70CATOM3575OLEU C 2076.1559.57228.1631.00 46.64OATOM3576NASP C 2085.2488.16529.6491.00 48.01NATOM3577CAASP C 2084.2089.12330.0561.00 49.81CATOM3578CBASP C 2083.0078.40230.6931.00 50.07CATOM3579CGASP C 2083.4337.41131.7741.00 53.03CATOM3580ODI ASP C 2084.2666.51931.4721.00 55.12OATOM3581OD2ASPC2Q82.9517.52732.9301.00 55.65OATOM3582CASP C 2084.73810.21230.9931.00 50.03CATOM3583OASP C 2084.09611.25231.1511.00 50.47OATOM3584NTHR C 2095.9149.95931.5791.00 50.42NATOM3585CATHR C 2096.61510.84232.5311.00 50.13CATOM3586CBTHR C 2097.62810.02433.4071.00 50.21CATOM3587OGl THR C 2098.7509.61832.6031.0049.13OATOM3588CG2THRC2096.9728.79334.0541.0049.28CΑΓΟΜ3589CTHR C 2097.42211.98631.8871.00 50.18CATOM3590OTHR C 2098.05012.78332.5811.0049.85OATOM3591NLEU C 2107.41212.06930.5671.00 50.91NATOM3592CALEU C 2108.29813.00629.8611.00 51.69CATOM3593CBLEU C 2108.89812.32028.6381.00 51.09CATOM3594CGLEU C 2109.99411.30828.9821.0051.14CATOM3595CDl LEU C 21010.40710.66027.6951.00 50.77CATOM3596CD2LEUC21011.22211.95329.7161.00 50.36CATOM3597CLEU C 2107.82214.45929.5211.00 52.13CATOM3598OLEU C 2108.59815.42529.7121.00 51.75OATOM3599NGLY C 2116.58914.62329.0211.00 52.20NATOM3600CAGLYC 2116.13515.94928.4941.00 53.09CATOM3601CGLYC 2117.13016.48127.4671.00 53.34CATOM3602OGLY C 2118.31616.37727.7101.00 53.40OATOM3603NGLU C 2126.68217.05226.3431.00 53.99NATOM3604CAGLU C 2127.58617.19325.1501.00 55.30CATOM3605CBGLU C 2126.84017.45123.8221.00 54.90C[0323]107ATOM3606CGGLU C 2125.61016.56723.5961.00 55.61CATOM3607CDGLU C 2124.42116.97424.4991.00 56.28CATOM3608OEl GLU C 2124.30118.19824.7291.00 55.28OATOM3609OE2GLUC2123.63216.09524.9751.00 53.34OATOM3610CGLU C 2128.83318.10225.3131.00 56.23CATOM3611OGLU C 2129.20318.87624.4191.00 56.21OATOM3612NGLU C 2139.44217.99426.4991.00 57.49NATOM3613CAGLU C 21310.85718.29026.7571.00 57.90CATOM3614CBGLU C 21311.01618.79528.1921.00 58.14CATOM3615CGGLU C 21310.48220.21028.4071.00 60.41CATOM3616CDGLU C 2138.95920.27228.4391.00 64.36CATOM3617OHl GLU C 2138.39920.38129.5671.00 64.56OATOM3618OE2GLUC2138.33120.20327.3451.00 64.26OATOM3619CGLU C 21311.64516.97326.5281.00 57.86CATOM3620OGLU C 21312.76616.76627.0411.00 58.35OATOM3621NSERC 21411.01816.10325.7321.00 56.61NATOM3622CASERC 21411.41914.73625.4211.00 55.57CATOM3623CBSER C 21412.21214.04526.5371.00 55.39CATOM3624OGSER C 21412.96712.95425.9901.00 55.81OATOM3625CSER C 21410.06314.09425.2461.00 54.60CATOM3626OSER C 2149.08914.54425.8361.00 55.35OATOM3627NTYRC 2159.97213.07624.4221.00 52.89NATOM3628CATYR C 2158.67812.45924.1191.00 51.76CATOM3629CBTYR C 2157.44013.11524.7951.00 51.06CATOM3630CGTYRC 2156.18412.59924.1221.00 50.31CATOM3631CDl TYRC 2155.76611.28024.3161.0048.67CATOM3632CEl TYR C 2154.68310.77223.6501.00 48.23CATOM3633CZTYR C 2154.00611.56422.7641.0048.43CATOM3634OHTYRC 2152.92511.04022.1181.0051.17OATOM3635CE2 TYRC 2154.39212.86122.5341.0048.10CATOM3636CD2TYR.C2155.49113.37123.2081.00 49.07CATOM3637CTYRC 2158.49712.51622.6261.00 51.33CATOM3638OTYRC 2158.19811.50821.9981.00 51.00OATOM3639NLYS C 2168.65413.72322.0821.00 50.89NATOM3640CALYS C 2168.68213.92820.6451.00 50.52CATOM3641CBLYS C 2168.45215.41120.2771.00 50.60CATOM3642CGLYS C 2166.96315.74120.0291.00 52.23CATOM3643CDLYS C 2166.17814.43119.7991.00 53.05CATOM3644CELYS C 2164.97414.51718.8751.00 53.61CATOM3645NZLYS C 2164.46913.10518.7171.00 53.43NATOM3646CLYS C 2169.93313.30319.9941.0049.89CATOM3647OLYS C 2169.78812.50919.0591.0048.63OATOM3648NASP C 21711.13913.63820.5011.00 49.62NATOM3649CAASPC 21712.34212.89920.0901.0049.56C[0324]ATOM3694CAGLN C 2237.8504.28916.0141.00 33.70CATOM3695CBGLN C 2236.8165.32515.5671.00 34.41CATOM3696CGGLN C 2237.2906.67115.1431.00 36.89CΑΓΟΜ3697CDGLN C 2236.2367.73815.3961.00 39.59CATOM3698OEl GLN C 2235.2877.52616.1661.0041.69OATOM3699NE2GLNC2236.4058.89814.7681.00 39.49NATOM3700CGLN C 2238.5973.58514.8801.00 32.37CATOM3701OGLN C 2238.0142.79414.1221.0032.07OATOM3702NLEU C 2249.9033.84114.8181.00 30.48NATOM3703CALEU C 22410.8023.13713.9091.00 29.87CATOM3704CBLEU C 22412.1283.91313.6691.0029.42CATOM3705CGLEU C 22412.1655.35113.1141.0028.51CATOM3706CDl LEU C 22413.5866.02013.1221.0023.96CATOM3707CD2LEUC22411.5685.39011.7561.00 26.80CATOM3708CLEU C 22411.0891.74514.4451.00 28.74CATOM3709OLEU C 22411.1720.81213.6751.00 28.67OATOM3710NLEU C 22511.2671.61015.7651.0028.93NATOM3711CALEU C 22511.4040.27616.4171.0028.00CATOM3712CBLEU C 22511.6810.41717.9091.0027.22CATOM3713CGLEU C 22513.0210.94918.4721.0026.14CATOM3714CDl LEU C 22512.7951.37719.9051.00 24.11CATOM3715CD2LEUC22514.118-0.14118.3391.00 24.23CATOM3716CLEU C 22510.120-0.56416.2491.00 28.21CATOM3717OLEU C 22510.175-1.75716.0241.0027.91OATOM3718NARG C 2268.9840.09616.4051.00 28.89NATOM3719CAARG C 2267.659-0.49416.2931.00 30.45CATOM3720CBARG C 2266.6140.53216.7451.0029.82CATOM3721CGARG C 2265.1900.02416.5731.00 30.51CATOM3722CDARG C 2264.2351.15116.4061.0031.15CATOM3723NEARG C 2264.5291.96615.2331.00 31.37NATOM3724CZARG C 2263.9823.15215.0261.00 30.90CATOM3725NHl ARG C 2263.1053.59615.8961.00 32.40NATOM3726NH2ARGC2264.3023.88513.9711.00 31.85NATOM3727CARG C 2267.311-1.02414.8881.00 30.92CATOM3728OARG C 2266.863-2.16514.7521.00 30.48OATOM3729NASP C 2277.515-0.17913.8731.00 32.58NATOM3730CAASP C 2277.308-0.54012.4471.00 33.65CATOM3731CBASP C 2277.4360.66611.4981.00 34.00CATOM3732CGASP C 2276.5141.80511.8561.00 36.21CATOM3733ODl ASP C 2275.6411.63612.7351.00 36.98OATOM3734OD2ASPC2276.6932.89811.2671.00 40.85OATOM3735CASP C 2278.290 ·-1.58211.9741.00 33.80CATOM3736OASP C 2277.931-2.39411.1251.00 33.79OATOM3737NASN C 2289.528-1.55812.4931.00 33.97N[0326]ATOM3738CAASN C 22810.484-2.64512.1861.00 34.57CATOM3739CBASN C 22811.900-2.36412.6951.00 34.61CATOM3740CGASN C 22812.729-1.50011.7401.00 35.15CATOM3741ODl ASN C 22812.331-1.21610.6131.00 34.91OATOM3742ND2ASNC22813.891-1.07012.2141.00 33.52NATOM3743CASN C 22810.033-3.93912.8271.00 35.02CATOM3744OASN C 22810.098-4.99612.1971.00 35.35OATOM3745NLEU C 2299.615-3.85914.0961.00 34.99NATOM3746CALEU C 2299.141-5.03914.8281.00 35.39CATOM3747CBLEU C 2298.788-4.68416.2831.00 35.14CATOM3748CGLEU C 2299.919-4.75317.306L00 35.86CATOM3749CDl LEU C 2299.580-3.98818.5651.00 35.30CATOM3750CD2LEUC22910.245-6.20317.6231.0037.38CATOM3751CLEU C 2297.919-5.66314.1351.00 35.55CATOM3752OLEU C 2297.807-6.87014.0681.00 35.38OATOM3753NTHR C 2307.007-4.80913.6701.00 35.97NATOM3754CATHR C 2305.822-5.20112.9211.00 36.64CATOM3755CBTHR C 2304.908-3.98212.6681.00 36.58CATOM3756OGl THR C 2304.532-3.40213.9181.0038.36OATOM3757CG2THRC2303.635-4.35111.9001.00 37.21CATOM3758CTHR C 2306.202-5.85511.5901.00 37.08CATOM3759OTHR C 2305.638-6.88911.2211.00 37.25OATOM3760NLEU C 2317.169-5.26810.8821.00 37.76NATOM3761CALEU C 2317.614-5.8069.5971.00 37.80CATOM3762CBLEU C 2318.559-4.8178.8941.00 38.09CATOM3763CGLEU C 2319.420-5.2437.6821.00 38.57CATOM3764CDl LEU C 2318.704-5.0126.3621.00 38.06CATOM3765CD2 LEU C 23110.772-4.4907.7121.00 37.64CATOM3766CLEU C 2318.231-7.1959.7871.00 38.05CATOM3767OLEU C 2317.854-8.1679.1021.00 38.14OATOM3768NTRP C 2329.129-7.29110.7651.00 38.32NATOM3769CATRP C 2329.838-8.52511.0951.00 38.08CATOM3770CBTRP C 23210.917-8.26612.1781.00 37.18CATOM3771CGTRP C 23212.060-7.34411.7151.00 36.29CATOM3772CDl TRP C 23212.403-7.06410.4191.00 35.04CATOM3773NEl TRP C 23213.463-6.19010.3801.00 34.62NATOM3774CE2TRPC23213.858-5.90111.6631.00 35.01CATOM3775CD2TRPC23213.012-6.62512.5391.00 35.14CATOM3776CE3 TRP C 23213.204-6.49113.9231.0034.51CATOM3777CZ3 TRP C 23214.250-5.65514.3911.00 35.49CATOM3778CH2TRPC23215.091-4.97313.4871.00 34.97CATOM3779CZ2TRPC23214.911-5.08012.1251.00 33.95CATOM3780CTRP C 2328.854-9,62511.5111.00 39.08CATOM3781OTRP C 2329.109-10.79811.2881.00 38.51O[0327]ATOM3782NTHR C 2337.712-9.21712.0671.00 40.58NATOM3783CATHR C 2336.700-10.11312.6271.0042.37CATOM3784CBTHR C 2336.288-9.57814.0141.00 42.40CATOM3785OGl THR C 2337.177-10.10915.0061.0042.90OATOM3786CG2THRC2334.837-9.94814.3741.00 44.27CATOM3787CTHR C 2335.451 --10.30611.7361.0043.20CATOM3788OTHR C 2334.455 ■-10.91012.1561.00 43.13OATOM3789NSER C 2345.515-9.79310.5071.00 44.52NATOM3790CASER C 2344.359-9.7319.6071.0045.30CATOM3791CBSER C 2344.598-8.6658.5271.00 44.91CATOM3792OGSER C 2345.756-8.9727.7661.0044.93OATOM3793CSER C 2344.023-11.0858.9681.00 46.27CATOM3794OSER C 2344.881 -11.9738.8831.00 45.88OATOM3795NASP C 2352.769 -11.2328.5301.00 47.36NATOM3796CAASP C 2352.310--12.4327.8141.0048.75CATOM3797CBASP C 2350.863 ■•12.2237.3241.0048.58CATOM3798CGASP C2350.346 ■-13.3536.4161.0049.25CATOM3799ODl ASPC 2350.032 -13.0515.2391.00 50.19OATOM3800OD2ASPC2350.220 -14.5186.8671.00 49.40OATOM3801CASPC2353.272-：12.7056.6481.00 49.95CATOM3802OASP C2354.122-13.6096.7071.00 50.33OATOM3803OXTASP C 2353.247-11.9965.6271.00 51.10OTERATOM3804NLEUD 1874.580-0.3322.0391.00 70.37NATOM3805CALEUD 1873.9740.5263.1101.00 70.27CATOM3806CBLEUD 1872.883-0.2463.8851.00 70.60CATOM3807CGLEUD 1871.395-0.1623.4781.00 71.36CATOM3808CDl LEUD 1870.7671.2103.7981.00 71.72CATOM3809CD2LEUD1871.129-0.5612.0111.00 72.57CATOM3810CLEUD 1874.9371.2654.0891.00 69.78CATOM3811OLEUD 1874.5372.3074.6251.00 69.92OATOM3812NGLND 1886.1670.7864.3541.00 68.87NATOM3813CAGLND 1886.781-0.4593.8541.00 67.85CATOM3814CBGLND 1887.896-0.1892.8291.00 68.03CATOM3815CGGLND 1887.4920.6621.6261.00 68.87CATOM3816CDGLN D 1888.6941.2250.8781.00 69.08CATOM3817OEl GLND 1888.7612.4330.6041.00 69.75OATOM3818NE2GLND 1889.6560.3530.5501.00 69.26NATOM3819CGLND 1887.277-1.3485.0231.00 66.43CATOM3820OGLND 1886.469-2.1475.5041.00 66.51OATOM3821NARGD 1898.523-1.2415.5411.00 64.53NATOM3822CAARGD 1899.569-0.1995.3371.00 62.26CATOM3823CBARGD 1898.9431.1815.4861.00 62.63CATOM3824CGARGD 1899.7182.3904.9901.00 63.40C[0328]ATOM3825CDARGD 189丨 9.0353.6265.5821.0064.28CATOM3826NEARGD 1898.6533.3496.9771.0064.90NATOM3827CZARG D 1897.4253.048 7.4011.0064.39CATOM3828NHl ARGD 1896.3963.0166.5621.00 63.66NATOM3829NH2ARGD 1897.2272.7908.6831.00 65.09NATOM3830CARGD 18910.679-0.3936.4191.00 60.31CATOM3831OARGD 18910.439-0.1477.6171.00 60.58OATOM3832NVALD 19011.877-0.8336.0301.00 57.14NATOM3833CAVALD 19012.878-1.2597.0341.00 54.38CATOM3834CBVALD 19013.460-2.6586.6981.00 54.53CATOM3835CGl VAL D 19013.857-2.7535.2071.00 54.97CATOM3836CG2VALD 19014.603-3.0427.6721.00 54.49CATOM3837CVALD 19013.987-0.2447.4161.00 52.13CATOM3838OVALD 19014.972-0.0776.6961.00 51.97OATOM3839NLEUD 19113.8250.3948.5771.00 48.88NATOM3840CALEU D 19114.5341.6498.8861.0046.00CATOM3841CRTJEUD 19113.5522.7689.3101.00 46.38CATOM3842CGLEUD 19112.5453.3368.2911.0046.76CATOM3843CDl LEUD 19113.1073.3676.8711.00 46.29CATOM3844CD2LEUD 19111.2822.5108.3441.0047.90CATOM3845CLEUD 19115.6071.5369.9411.00 43.16CATOM3846OLEUD 19115.5660.64510.7701.00 42.57OATOM3847NSEPD 19216.5602.4659.9021.00 40.37NATOM3848CASEPD 19217.5422.62510.9761.00 36.60CATOM3849CBSEPD 19218.9542.36110.4501.00 37.39CATOM3850OGSEPD 19219.2023.1259.2801.00 34.02OATOM3851PSEPD 19220.7123.1108.7441.0031.52PATOM3852OlP SEPD 19220.8354.2167.5751.00 30.51OATOM385302PSEPD 19221.0361.6338.2721.00 32.32OATOM385403P SEPD 19221.7453.6239.8891.0027.64OATOM3855CSEPD 19217.4124.03611.5691.00 36.61CATOM3856OSEPD 19216.5514.80111.1521.00 35.91OATOM3857NALAD 19318.2424.37712.5501.00 35.51NATOM3858CAALAD 19318.1335.67313.2181.00 35.75CATOM3859CBALAD 19319.1395.78514.3851.0035.22CATOM3860CALAD 19318.3026.84512.2571.00 36.23CATOM3861OALAD 19319.1166.76111.3281.00 35.98OATOM3862NPROD 19417.5477.94912.4961.00 36.52NATOM3863CAPROD 19417.5509.13711.6271.00 37.25CATOM3864CBPROD 19416.2399.83911.9911.0037.11CATOM3865CGPROD 19415.9499.42913.4011.00 36.07CATOM3866CDPRO D 19416.6508.11913.6621.00 36.09CATOM3867CPROD 19418.72910.08911.9161.00 38.39CATOM3868OPROD 19418.84511.14111.2881.00 38.21O[0329]CN 102947445 A书明说110/376 页ATOM3869NPHED 195 19.5879.72112.8611.00 39.13NATOM3870CAPHED 195 20.754ί 10.55213.167 1.0040.38CATOM3871CBPHED 195 20.68111.15914.578 1.00 39.60CATOM3872CGPHED 195 20.612I 10.14715.708 1.0038.21CATOM3873CDl PHED 195 19.3749.69616.1841.00 37.35CATOM3874CEl PHE D 195 19.2908.81217.2641.00 37.85CATOM3875CZPHED195 20.4728.37717.9031.00 37.49CATOM3876CE2PHED 195 21.7218.84217.4381.00 36.36CATOM3877CD2 PHED 195 21.7759.73016.3551.00 35.78CATOM3878CPIffiD 195 22.0819.83412.9241.0041.26CATOM3879OPHED195 22.4638.83113.5661.0042.02O·ATOM3880OXTPHED195 22.78910.28212.022：1.0042.23OTERATOM3881NALAE6 -32.46218.199-11.2241.00 48.84NATOM3882CAALAE6 -33.22418.404-9.9561.0048.82CATOM3883CBALAE6 -33.72417.037-9.3931.0048.80CATOM3884CALAE6-32.33119.157-8.9481.00 48.51CATOM3885OALAE6-31.11118.980-8.9901.00 48.90OATOM3886NASPE7 -32.92619.955-8.0431.0047.73NΑΓΟΜ3887CAASPE7-32.16720.954-7.2461.0046.53CATOM3888CBASPE7 -32.02522.301-8.0521.0046.41CATOM3889CGASPE7 -30.65822.432-8.8291.00 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-20.44835.0811.3881.0026.47CATOM4160CD2LEUE43-18.49535.251-0.2011.00 29.49CATOM4161CLEUE43 -22.08637.959-1.3561.0028.82CATOM4162OLEUE43 -22.10638.206-2.5711.00 28.75OATOM4163NGLUE44 -21.98438.919-0.4291.00 29.32NATOM4164CAGLUE44 -21.96140.345-0.7881.0029.40CATOM4165CBGLUE44 -22.71141.2070.2381.0029.48CATOM4166CGGLUE44 -22.66942.722-0.1021.0029.08CATOM4167CDGLUE44 -23.90043.5050.3331.0028.87CATOM4168OEl GLU E44 -24.63043.0581.2421.00 33.97OATOM4169OE2GLUE44-24.13744.584-0.2331.00 27.42OATOM4170CGLUE44 -20.59240.984-1.0881.00 29.20CATOM4171OGLUE44-19.63240.818-0.3461.00 30.05OATOM4172NLEUE45 -20.56641.779-2.1501.00 28.72NATOM4173CALEUE45 -19.37642.431-2.6451.0029.53CATOM4174CBLEUE45-18.81541.728-3.8891.0029.60CATOM4175CGLEUE45 -17.65440.720-3.8971.00 29.53C[0336]ATOM4176CDl LEUE45-17.37440.055■2.5701.00 32.02CATOM4177CD2 LEUE45-17.95539.667-4.9251.0031.89CATOM4178CLEUE45-19.76143.856-2.9881.0029.80CATOM4179〇LEUE45 -20.82944.131-3.5701.00 29.51OATOM4180NLYSE46-18.89744.771-2.5781.00 29.12NATOM4181CALYSE46-19.07646.156-2.8521.00 29.13CATOM4182CBLYSE46-18.01046.935-2.0711.0029.67CATOM4183CGLYS E46-18.19546.911-0.5491.0029.88CATOM4184CDLYSE46-17.12647.7730.1251.00 31.75CATOM4185CELYSE46-17.17647.6761.6641.00 32.51CATOM4186NZLYSE46-16.45446.4292.1201.0036.57NATOM：4187CLYSE46-18.86346.326-4.3521.00 28.08CATOM4188OLYSE46-17.99345.657-4.8971.00 28.40OATOM4189NPROE47-19.62547.228-5.0211.0027.47NATOM4190CAPROE47-19.24047.662-6.3601.00 27.92CATOM4191CRPROE47 -20.03548.946-6.5541.00 27.14CATOM4192CGPROE47 -21.23348.785-5.6541.00 27.13CATOM4193CDPROE47-20.87047.878-4.561L00 27.02CATOM4194CPROE47-17.72647.961-6.4891.00 29.39CATOM4195OPROE47-17.09847.525-7.4561.0029.94OATOM4196NSERE48-17.15648.716-5.5471.00 30.37NATOM4197CASERE48-15.69849.069-5.542L00 31.15CATOM4198CBSERE48-15.35549.812-4.2551.00 30.60CATOM4199OGSERE48-15.43148.931-3.1501.00 33.27OATOM4200CSERE48-14.72847.875-5.7101.00 31.47CATOM4201OSERE48-13.68248.004-6.3371.00 32.96OATOM4202NMETE49-15.07846.726-5.1381.0031.44NATOM4203CAMETE49-14.32345.492-5.3101.00 32.99CATOM4204CBMETE49-14.71144.484-4.2091.00 33.53CATOM4205CGMETE49-14.64344.989-2.7311.00 36.41CATOM4206SDMETE49-15.64544.049-1.4871.00 40.73SATOM4207CEMETE49-14.86344.742-0.0131.0039.88CATOM4208CMETE49-14.48644.818-6.6931.00 30.86CATOM4209OMETE49-13.66743.991-7.0601.0031.13OATOM4210NVALE50-15.54045.151-7.4431.00 29.46NATOM4211CAVALE50-15.93344.380-8.6661.0027.32CΑ1ΌΜ4212CBVALE50-17.35243.691-8.5171.0026.65CATOM4213CGl VALE50-17.37542.717-7.3741.00 25.44CATOM4214CG2VALE50-18.47744.725-8.3471.00 25.78CATOM4215CVALE50-15.85745.166-9.9921.0026.42CATOM4216OVALE50-16.44044.782-11.0151.00 26.75OATOM4217NTHRE51-15.13346.269-9.9661.0025.17NATOM4218CATIIRE51 -15.04147.193--11,0701.00 24.90CATOM4219CBTHRE51-14.24948.431 -■10.6191.0025.49C[0337]121ATOM4220OGl THRE51-12.94947.990 -10.2521.0026.23OATOM4221CG2THRE51-14.91749.100 -9.4051.00 24.75CATOM4222CTHRE51-14.31446.608-12.2931.0025.17CATOM4223OTHRE51-14.56946.984-13.4221.0025.08OATOM4224NHISE52-13.36345.722-12.0531.00 25.92NATOM4225CAHISE52.-12.72844.967-13.1161.00 25.89CATOM4226CBHISE52-•11.21145.092-13.0411.0025.99CATOM4227CGHISE52-■10.75446.490-13.2791.0029.70CATOM4228NDl HIS E52-10.69747.428-12.2681.00 32.36NATOM4229CEl HIS E52-：10.32448.588-12.7721.00 32.79CATOM4230NE2HISE52-：10.16748.443-14.0741.00 32.04NATOM4231CD2 fflS E52-10.43747.141 -14.4201.00 29.76CATOM4232CHISE52-：13.12143.509-13.0441.00 24.91CATOM4233OHISE52-13.52643.009-11.9801.00 24.17OATOM4234NGLNE53-12.95042.842-14.1781.0023.06NATOM4235CAGLNE53-13.20541.423-14.3031.00 23.05CATOM4236CBGLNE53-12.93740.962-15.7511.00 22.53CATOM4237CGGLNE53-11.51440.785 -16.0761.00 21.31CATOM4238CDGLNE53-11.28840.364-17.4741.00 20.66CATOM4239OEl GLNE53.-10.75339.293-17.7101.00 22.30OATOM4240NE2GLNE53.-11.67341.212-18.4381.00 24.49NATOM4241CGLNE53.-12.50440.551 -13.2511.00 22.35CATOM4242OGLNE53.-11.33840.795 -12.8921.0024.48OATOM4243NPROE54-■13.21139.539-12.7371.00 21.26NATOM4244CAPROE54-12.55538.649-11.8041.0020.03CATOM4245CBPROE54-13.73237.963-11.1291.0020.78CATOM4246CGPROE54-14.81337.893-12.2111.00 19.34CATOM4247CDPROE54-14.60739.124-13.0361.0021.34CATOM4248CPROE54-11.69337.620-12.5551.00 19.90CATOM4249OPROE54-■11.72837.553 -13.7861.00 19.41OATOM4250NARGE55.-10.91936.836-11.8161.0019.89NATOM4251CAARGE55-10.26735.678-12.3741.0021.29CATOM4252CBARGE55-8.98935.348-11.6261.00 21.55CATOM4253CGARGE55-7.887'36.308-11.9741.00 21.87CATOM4254CDARGE55-6.73436.132-11.0301.00 23.80CATOM4255NEARGE55-5.68637.119-11.3101.00 23.93NATOM4256CZARGE55-5.58038.312-10.7091.00 26.74CATOM4257NHl ARG E55-4.55139.127-11.0441.0020.78NATOM4258NI-I2ARGE55-6.46238.675 -9.7421.00 22.17NATOM4259CARGE55-•11.28034.579-12.2461.00 21.32CATOM4260OARGE55.-11.93634.519-11.2411.00 22.69OATOM4261NVALE56-11.43733.756-13.2831.00 21.27NATOM4262CAVALE56-12.49632.737-13.3331.0020.71CATOM4263CBVALE56-13.69433.154-14.2701.0019.85C[0338][0339]ATOM4264CGl VALE56-■14.66732.040-14.4801.0021.31CATOM4265CG2 VALE56-■14.41034.339-13.7381.00 20.01CATOM4266CVALE56-■11.84831.438-13.8161.0020.95CATOM4267OVALE56--11.57831.263-14.9991.00 19.49OATOM4268NGLUE57-11.57930.540-12.8721.0021.32NATOM4269CAGLUE57-11.03829.256-13.2151.0022.51CATOM4270CBGLUE57-10.25428.710-12.0451.0021.99CATOM4271CGGLUE57-9.19929.737-11.5281.00 22.21CATOM4272CDGLUE57-8.36629.173-10.3961.00 28.82CATOM4273OEl GLUE57-8.73928.098 -9.8851.0029.39OATOM4274OE2GLUE57-7.32629.791 -10.0131.00 32.26OATOM4275CGLUE57'-12.17628.330-13.6631.0023.93CATOM4276OGLUE57-13.25728.340-13.0801.00 22.14OATOM4277NVALE58-■11.92627.579-14.7381.0025.53NATOM4278CAVALE58-12.92026.611-15.2411.0027.58CATOM4279CBVALE58-13.41026.928-16.7051.00 27.14CATOM4280CGl VAL E58-13.46128.411 -16.9591.00 26.59CATOM4281CG2VALE58-12.58126.274-17.7561.00 28.03CATOM4282CVALE58-12.26925.244-15.1081.00 28.97CATOM4283OVALE58-11.07525.108-15.3851.00 29.83OATOM4284NGLYE59-13.02024.249-14.6461.00 29.79NATOM4285CAGLYE59-12.45122.933 -14.3961.00 30.35CATOM4286CGLYE59-12.39922.143-15.6761.00 31.66CATOM4287OGLYE59-12.16622.698-16.7571.00 31.99OATOM4288NGLYE60-12.65520.844-15.5651.00 33.06NATOM4289CAGLYE60-12.50419.938-16.7041.00 34.10CATOM4290CGLYE60-11.16119.236-16.6251.00 34.83CATOM4291OGLYE60-10.28419.627-15.8371.00 34.76OATOM4292NASNE61-10.99518.184-17.4171.00 35.13NATOM4293CAASNE61-9.68617.538-17.5051.0036.33CATOM4294CBASNE61-9.74016.085 -16.9921.00 37.49CATOM4295CGASNE61-9.59515.986-15.4731.0040.37CATOM4296ODl ASN E61-8.62316.499-14.8891.00 43.03OATOM4297ND2ASNE61 --10.55915.310-14.8261.00 44.11NATOM4298CASNE61-9.08017.618-18.9031.00 35.17CATOM4299OASNE61-8.00117.141-19.1321.00 35.06OATOM4300NASPE62-9.75118.310-19.8071.00 34.48NATOM4301CAASPE62-9.41618.249 -21.2041.00 33.35CATOM4302CBASPE62-■10.45617.340-21.8841.00 34.01CATOM4303CGASPE62--10.08416.957 -23.3021.00 33.47CATOM4304ODl ASP E62-10.69316.003 -23.8241.00 34.30OATOM4305OD2ASPE62-9.21617.607 -23.9111.00 31.61OATOM4306CASPE62-9.39119.649 -21.8281.00 32.83CATOM4307OASPE62-10.43320.286 -21.9781.00 33.02O
ATOM4352OHTYRE67-14.92420.997-19.4801.00 26.75OATOM4353CE2TYRE67 -16.45522.875-19.4901.00 25.23CATOM4354CD2TYRE67-16.72824.187-19.8171.0024.27CATOM4355CTYRE67-16.84427.970-22.6321.00 24.11CATOM4356OTYRE67-15.99228.806-22.9931.0024.98OATOM4357NTHRE68-18.11928.292-22.3981.0023.63NATOM4358CATHRE68-18.60329.679丨-22.5301.0023.46CATOM4359CBTHRE68 -19.69429.830-23.6301.00 23.59CATOM4360OGl THRE68-19.06829.640-24.8941.00 25.84OATOM4361CG2THRE68 -20.29931.211-23.6711.00 23.40CATOM4362CTHRE68 -19.05330.225 -21.2011.00 22.53CATOM4363OTHRE68 -19.72729.559-20.4611.0020.89OATOM4364NLEUE69-18.60231.440-20.8951.00 23.14NATOM4365CALEUE69-18.95732.083-19.6391.0022.85CATOM4366CBLEUE69-17.67932.470-18.8661.00 21.96CATOM4367CGLEUE69-17.88933.268-17.5791.00 20.90CATOM4368CDl LEUE69-18.39132.377 ■-16.4701.0016.86CATOM4369CD2LEUE69-16.55733.964-17.2041.0021.06CATOM4370CLEUE69-19.84533.316-■19.8921.0023.33CATOM4371OLEUE69-19.51534.170--20.7191.00 23.09OATOM4372NVALE70 -20.96933.361 -19.1751.00 23.51NATOM4373CAVALE70 -21.94634.450-19.2211.00 23.75CATOM4374CBVALE70 -23.38533.870-19.4871.00 24.90CATOM4375CGl VALE70 -24.43034.972 -■19.5871.00 25.04CATOM4376CG2VALE70 -23.38633.033 -20.7501.00 24.71CATOM4377CVALE70 -21.97635.128-17.8531.0022.99CATOM4378OVALE70 -21.95934.452 -16.8281.00 24.27OATOM4379NMETE71 -22.03436.450-17.8321.0021.12NATOM4380CAMETE71 -22.28937.141-16.5941.00 20.18CATOM4381CBMETE71 -21.02637.945-16.1701.0018.01CATOM4382CGMETE71 -21.25638.708-14.9481.0019.05CATOM4383SDMETE71 -19.74739.671-14.5901.0019.39SATOM4384CEMETE71 -20.39040.552-13.2121.00 15.76CATOM4385CMETE71 -23.43838.100.-16.7761.0019.03CATOM4386OMETE71 -23.38838.971-17.6151.00 19.67OATOM4387NVALE72 -24.42538.044 -15.9091.0018.77NATOM4388CAVALE72-25.61438.821-16.1751.0018.68CATOM4389CBVALE72 -26.75437.902-16.8161.00 18.59CATOM4390CGl VALE72 -26.46237.576-18.2431.0018.70CATOM4391CG2VALE72-26.91536.631 -16.0281.0015.72CATOM4392CVALE72 -26.19239.362 -14.9261.0018.79CATOM4393OVALE72 -26.09138.711-13.8871.0019.38OATOM4394NASPE73 -26.86040.505 -15.0451.0019.10NATOM4395CAASPE73 -27.67641.069.-13.9491.0022.22C[0341][0342]ATOM4396CBASPE73 -27.415ATOM4397CGASPE73 -27.970ATOM4398ODl ASPE73 -28.920ATOM4399OD2ASPE73 -27.438ATOM4400CASPE73 -29.196ATOM4401OASPE73 -29.747ATOM4402NPROE74 -29.845ATOM4403CAPROE74 -31.298ATOM4404CBPROE74-31.531ATOM4405CGPROE74 -30.442ATOM4406CDPROE74 -29.246ATOM4407CPROE74-32.183ATOM4408OPROE74 -33.420ATOM4409NASPE75 -31.528ATOM4410CAASPE75 -32.180ATOM4411CBASPE75 -31.598ATOM4412CGASPE75 -31.811ATOM4413ODl ASP E75 -32.942ATOM4414OD2ASPE75 -30.835ATOM4415CASPE75 -31.906ATOM4416OASPE75 -31.886ATOM4417NALAE76-31.590ATOM4418CAALAE76 -31.383ATOM4419CBALAE76-30.491ATOM4420CALAE76-32.731ATOM4421OALAE76 -33.584ATOM4422NPROE77 -32.966ATOM4423CAPROE77 -32.138ATOM4424CBPROE77 -32.549ATOM4425CGPROE77 -33.967ATOM4426CDPROE77 -34.208ATOM4427CPROE77 -32.379ATOM4428OPROE77 -31.605ATOM4429NSERE78 -33.422ATOM4430CASERE78 -33.709ATOM4431CBSERE78 -34.728ATOM4432OGSERE78 -35.181ATOM4433CSERE78 -34.322ATOM4434OSERE78 -35.171ATOM4435NPROE79 -33.955ATOM4436CAPROE79 -34.637ATOM4437CBPROE79-33.993ATOM4438CGPROE79 -33.542ATOM4439CDPROE79 -32.92942.583-13.757 43.099-12.444 42.441 -11.926 44.125-11.887 40.864-14.215 41.544-15.082 39.925-13.50039.687-13.717 38.319-13.066 38.312-11.889 38.966-12.533 40.781 -13.076 40.777-13.264 41.708-12.357 42.696-11.504 42.670-10.08141.395-9.369 40.947 -9.292 40.850 -8.832 44.109-12.001 45.035-11.193 44.267-13.280 45.567-13.869 45.433-15.065 46.153-14.269 45.410-14.832 47.460-13.959 48.421 -13.186 49.782-13.768 49.556-14.371 48.089-14.479 48.383-11.666 48.952-10.88447.690-11.241 47.522 -9.820 48.586 -9.38748.395-8.074 46.135 -9.673 45.753 -10.523 45.392 -8.589 44.154 -8.279 43.744 -6.95945.036-6.387 45.662 -7.5661.0020.671.0026.021.0027.471.0026.28 1.0021.661.0024.081.0022.021.0022.761.0021.921.0022.061.0020.691.0024.60 1.0023.621.0024.481.0025.11 1.0025.791.0024.661.0028.661.0024.861.0025.181.0027.041.0024.361.0023.791.0023.991.0024.931.0024.201.0024.941.0025.091.0025.161.0025.881.0024.32 1.0025.58 1.0025.841.0025.441.0024.591.0024.401.0021.561.0025.95 1.0025.771.0026.271.0026.611.0025.92 1.0026.811.0026.25OOCONCCCCCONCCCOOCONCCCONCCONOCONCCCCATOM4440CPROE79 -36.15344.332-8.0831.00 27.74CATOM4441OPROE79 -36.88543.371-8.2271.0028.13OATOM4442NSERE80 -36,60845.542-7.7241.00 29.37NATOM4443CASERE80 -38.03945.820-7.5181.00 29.93CATOM4444CBSERE80 -38.23647.019-6.6311.0028.43CATOM4445OGSERE80-37.63446.775-5.3861.00 29.18OATOM4446CSERE80-38.74846.058-8.8331.00 30.46CATOM4447OSERE80 -39.96645.979-8.8901.00 32.39OATOM4448NASPE81 -37.98046.371-9.8741.00 30.20NATOM4449CAASPE81 -38.52146.533-11.2191.00 29.11CATOM4450CBASPE81 -39.00247.960 ■-11.4331.00 29.28CATOM4451CGASPE81 -39.86148.074-12.6621.0030.75CATOM4452ODl ASPE81 -40.57547.080 -12.9321.00 32.40OATOM4453OD2ASPE81-39.79849.109-13.3641.0031.14OATOM4454CASPE81 -37.49246.215-12.2931.0028.83CATOM4455OASPE81 -36.95447.153-12.9041.0028.53OATOM4456NPROE82 -37.21044.901 --12.5251.0028.79NATOM4457CAPROE82 -36.16044.382-13.4541.00 28.80CATOM4458CBPROE82 -36.10442.880-13.1501.0028.01CATOM4459CGPROE82 -37.04742.636-11.9941.00 28.34CATOM4460CDPROE82 -37.92943.803-11.8381.00 28.10CATOM4461CPROE82 -36.38944.498 -14.9521.00 29.03CATOM4462OPROE82 -35.93443.623-■15.6681.00 29.49OATOM4463NASNE83 -37.02245.555-15.4411.0029.73NATOM4464CAASNE83 -37.41945.629-16.8661.00 30.34CATOM4465CBASNE83 -38.18446.937-17.1401.00 30.49CATOM4466CGASNE83 -37.32648.143-16.9761.00 30.33CATOM4467ODl ASNE83 -36.93248.784 --17.9631.00 30.34OATOM4468ND2ASNE83 -36.97948.448 ■■15.7291.0026.90NATOM4469CASNE83-36.31745.422-17.9331.00 30.46CATOM4470OASNE83 -36.59045.408-■19.1451.00 30.14OATOM4471NLEUE84 -35.07145.259-■17.4791.00 30.33NATOM4472CALEUE84 -33.93445.173-18.3981.00 29.45CATOM4473CBLEUE84 -32.86946.265-18.1381.0029.43CATOM4474CGLEUE84-33.15647.757-18.2991.00 29.53CATOM4475CDl LEUE84 -31.88948.587-17.9121.00 26.93CATOM4476CD2 LEUE84 -33.57948.083 -19.7261.00 28.61CATOM4477CLEUE84 -33.30543.810-18.2801.00 28.24CATOM4478OLEUE84 -32.30543.558-18.9321.00 28.49OATOM4479NARGE85 -33.89542.954 ■-17.4441.00 26,99NATOM4480CAARGE85 -33.47541.577-17.2531.0026.52CATOM4481CBARGE85 -34.53840.866-16.4371.00 26.39CATOM4482CGARGE85 -34.19839.448-16.0831.00 26.53CATOM4483CDARGE85 -35.30538.806■15.3391.0029.27C[0343]ATOM4484NEARGE85 -35.239丨 39.123 -13.9241.00 30.51NATOM4485CZARGE85 -36.12838.733 -13.0211.00 29.10CATOM4486NHl ARGE85 -37.18138.001 -13.3881.0028.15NATOM4487NH2ARGE85 -35.94639.069-11.7491.00 26.87NATOM4488CARGE85 -33.29940.861 -18.6011.0027.50CATOM4489OARGE85 -34.14941.017-19.4751.00 27.76OATOM4490NGLUE86 -32.19840.132-18.8221.00 28.48NATOM4491CAGLUE86 -30.98240.164-17.9901.00 28.63CATOM4492CBGLUE86 -30.26138.809-17.9881.00 28.68CATOM4493CGGLUE86 -31.01237.6] 8-17.4421.00 28.64CATOM4494CDGLUE86 -30.93136.402-18.4041.00 29.57CATOM4495OEl GLUE86 -30.13236.418-19.3511.0029.90OATOM4496OE2GLUE86-31.65935.416-18.2231.0025.47OATOM4497CGLUE86 -30.02641.188-18.5911.0028.79CATOM4498OGLUE86 -29.89741.279-19.8301.00 29.43OATOM4499NTYRE87 -29.30441.916-17.7351.0027.79NATOM4500CATYRE87 -28.23942.774-18.2361.00 26.27CATOM4501CBTYRE87 -28.04343.978-17.3231.0026.08CATOM4502CGTYRE87 -27.27445.039-18.0391.0025.21CATOM4503CDl TYRE87 -27.90045.835-19.0131.00 26.13CATOM4504CEl TYRE87-27.19946.797-19.7121.00 27.02CATOM4505CZTYRE87 -25.83646.959-19.4401.0025.19CATOM4506OHTYRE87 -25.12847.878 -20.1401.00 25.62OATOM4507CE2TYRE87 -25.19546.154-18.5261.00 23.23CATOM4508CD2TYRE87-25.91245.208-17.8151.0023.80CATOM4509CTYRE87 -26.90542.036-18.3541.00 26.07CATOM4510OTYRE87 -26.31041.647-17.3391.0026.32OATOM4511NLEUE88-26.41341.899-19.5811.00 25.57NATOM4512CALEUE88-25.12841.271 -19.8761.0023.49CATOM4513CBLEUE88 -25.06640.984 -21.3841.00 22.88CATOM4514CGLEUE88-23.90040.127 -21.8921.0022.52CATOM4515CDl LEUE88 -23.74238.869 -21.0211.00 21.99CATOM4516CD2LEUE88 -24.03739.782 -23.3541.00 22.58CATOM4517CLEUE88 -23.88442.106-19.4591.0023.26CATOM4518OLEUE88 -23.55243.102-20.1061.00 22.35OATOM4519NHISE89 -23.18341.659-18.4211.0022.84NATOM4520CAHISE89-21.91442.286-18.0091.00 22.34CATOM4521CBHISE89 -21.71942.223 -16.5001.00 22.05CATOM4522CGHISE89 -22.61443.171-15.7911.0020.54CATOM4523NDl HIS E89 -22.36644.520-15.7661.00 21.24NATOM4524CEl HIS E ：89-23.369 ‘45.145-15.1781.0021.54CATOM4525NE2HISE ；89-24.281 .44.251 -14.8571.00 18.78NATOM4526CD2 HIS E89-23.84343.008-15.2521.0022.81CATOM4527CHISE89 -20.697 ‘41.797-18.7391.0022.40C[0344]ATOM4528OHISE89-■19.79642.564-18.988L00 22.04OATOM4529NTRPE90-20.68840.542-19.1571.0022.52NATOM4530CATRPE90-19.44639.966-19.6701.0022.30CATOM4531CBTRPE90-18.58239.575-18.4861.0021.76CATOM4532CGTRPH90-17.16239.282-18.7701.0023.99CATOM4533CDl TRPE90-16.42239.667 -19.8701.0024.21CATOM4534NEl TRPE90.-15.12439.224-19.7361.00 21.35NATOM4535CE2TRPE90-•14.99638.573-18.5321.00 24.26CATOM4536CD2TRPE90-16.24938.619-17.8831.0023.85CATOM4537CE3TRPE90-16.38938.006-16.6251.0022.82CATOM4538CZ3TRPE90-•15.27937.371 -16.0551.0023.62CATOM4539CH2TRPE90.-14.03537.356-16.7131.0023.68CATOM4540CZ2TRPE90-13.86837.955-17.9471.0026.05CATOM4541CTRPE90-■19.73738.728 -20.4431.0021.14CATOM4542OTRPE90 -20.55537.976 -20.0061.0020.22OATOM4543NLEUE91-19.02238.488-21.5461.0021.18NATOM4544CALEUE91-19.23337.243 -22.3081.0020.86CATOM4545CBLEUE91-20.32537.435 -23.3561.0020.35CATOM4546CGLEUE91-20.62336.279 -24.3051.0019.96CATOM4547CDl LElJ E91-21.41435.215-23.5841.00 21.14CATOM4548CD2 LEUE91-21.42736.852 -25.4271.00 22.91CATOM4549CLEUE91 ■-17.97936.691 -22.9471.00 20.30CATOM4550OLEUE91-17.40137.331-23.7621.00 22.21OATOM4551NVALE92--17.53735.513-22.5431.00 21.02NATOM4552CAVALE92-16.32934.930-23.1131.00 21.28CATOM4553CBVALE92-14.95035.278 -22.2781.0021.69CATOM4554CGl VALE92--13.94334.142-22.2331.0018.77CATOM4555CG2VALE92-■15.22535.828 -20.9271.0018.31CATOM4556CVALE92-■16.54133.493 -23.5041.0021.84CATOM4557OVALE92-■17.28132.772-22.8451.00 23.17OATOM4558NTHRE93-15.93933.105 -24.6231.00 22.60NATOM4559CATHRE93-16.15331.756 -25.2141.0023.70CATOM4560CDTHRE93-17.05331.838-26.4831.0022.88CATOM4561OGl THRE93-16.43232.679 -27.4621.00 23.84OATOM4562CG2THRE93-18.32932.518-26.1121.00 24.54CATOM4563CTHRE93-■14.82131.077-25.4811.00 23.30CATOM4564OTHRE93.-13.80731.704-25.2701.00 23.53OATOM4565NASPE94-14.80629.790 -25.8671.0023.11NATOM4566CAASPE94-13.55929.168 -26.3281.0022.73CATOM4567CBASPE94.-13.02629.894-27.5871.00 21.44CATOM4568CGASPE94-13.97029.777 -28.8101.0024.95CATOM4569ODl ASPE94-14.82928.842 -28.8801.0020.28OATOM4570OD2ASPE94-13.81830.638-29.7181.0027.15OATOM4571CASPE94-12.49729.196 -25.1991.0022.71C[0345]ATOM4572OASPE94-11.30729.360-25.4321.00 23.82OATOM4573NILEE95-12.95929.036-23.9751.00 22.90NATOM4574CAILEE95-12.10728.906 -22.8071.00 22.12CATOM4575CBILEE95.-12.85229.278 -21.5171.0021.28CATOM4576CGl ILE E95-13.48530.666-21.6361.00 20.69CATOM4577CDl ILEE95-14.55831.000-20.5281.00 21.39CATOM4578CG2ILEE95-11.96729.070 -20.3341.0021.17CATOM4579CILEE95-11.77527.435 -22.7531.0022.77CATOM4580OILEE95-12.68226.599 -22.5761.0023.12OATOM4581NPROE96-10.47827.104-22.9341.0022.53NATOM4582CAPROE961-10.09125.710-22.8511.0021.83CATOM4583CBPROE96-8.62225.718-23.3131.00 21.25CATOM4584CGPROE96-8.39327.040 -23.9951.0018.60CATOM4585CDPROE96-9.330I 27.979 -23.2581.00 21.78CATOM4586CPROE96-10.22125.186-21.4301.0022.73CATOM4587OPROE96-9.89725.917-20.4241.0022.83OATOM4588NGLYE97.-10.65223.930-21.3561.0021.10NATOM4589CAGLYE97-10.78623.195 -20.1141.00 22.74CATOM4590CGLYE97-9.47523.200-19.3621.00 23.55CATOM4591OGLYE97-8.39723.104-19.9941.00 23.70OATOM4592NTHRE98-9.56523.330-18.0351.0023.31NATOM4593CATHRE98-8.39223.406-17.1121.00 23.24CATOM4594CBTHRE98-7.20922.415-17.4601.0023.51CATOM4595OGl THRE98-6.60022.792-18.6911.0023.34OATOM4596CG2THRE98-7.62720.966-17.5041.0026.57CATOM4597CTHRE98-7.78924.796-16.9361.00 22.84CATOM4598OTHRE98-6.90425.021 -16.0651.00 23.22OATOM4599NTHRE99-8.25425.730-17.7541.00 23.40NATOM4600CATHRE99-7.69927.092-17.7881.00 22.74CATOM4601CBTHRE99-7.22827.487-19.2391.0022.08CATOM4602OGl THRE99-8.32527.838 -20.0711.0024.70OATOM4603CG2THRE99-6.48326.370-19.8971.0020.21CATOM4604CTHRE99-8.54828.166-17.0111.0022.54CATOM4605OTHRE99-8.98927.908-15.8761.0023.29OATOM4606NALAE 100-8.73629.346-17.5971.00 21.90NATOM4607CAALAE 100-9.48330.454-17.0071.0021.56CATOM4608CBALAE 100-8.52731.390-16.1431.00 22.23CATOM4609CALAE 100-：10.08931.278-18.1181.0021.23CATOM4610OALAE 100-9.75531.106-19.2751.0022.44OATOM4611NALAE 101 -：10.94932.219-17.7711.0021.24NATOM4612CAALAE 101 ■-11.62033.017-18.7731.00 22.01CATOM4613CBALAE 101 -■12.76433.773-18.1551.00 21.96CATOM4614CALAE 10110.67933.943 -19.5441.0021.87CATOM4615OALAE 101 -10.96434.291 -20.7141.0022.03O[0346]ATOM4616NSERE 102-9.57034.338-18.8921.0022.23NATOM4617CASERE 102-8.50435.130-19.4921.00 21.05CATOM4618CBSERE 102-7.41635.462-18.4161.00 20.96CΑΓΟΜ4619OGSERE 102-6.71634.266-18.0121.00 19.49OATOM4620CSERE 102-7.82934.403 -20.6851.0021.12CATOM4621OSERE 102-7.23234.998 -21.5241.0020.40OATOM4622NPHEE 103-7.91433.086 -20.7041.0023.94NATOM4623CAPHEE 103-7.52832.237-21.8461.00 24.74CATOM4624CBPHEE 103-7.31530.802-21.3601.00 24.09CATOM4625CGPHEE 103-6.03330.605 -20.6121.00 22.41CATOM4626CDl PHEE 103-5.91031.025-19.2951.0023.57CATOM4627CEl PHEE 103-4.72630.834-18.5741.0017.73CATOM4628CZPHEE 103-3.63530.234-19.1981.0019.71CATOM4629CE2PHEE103-3.71729.820 -20.5071.00 24.48CATOM4630CD2PHEE 103-4.94429.984 -21.2251.0023.42CATOM4631CPHEE 103-8.52132.190 -22.9791.00 25.55CATOM4632OPHEE 103-8.19231.653 -24.0701.0027.31OATOM4633NGLYE 104-9.73032.705 -22.7571.0025.99NATOM4634CAGLYE 104-10.82032.527 -23.7381.0025.29CATOM4635CGLY El 04-10.91933.632 -24.7731.00 26.06CATOM4636OGLYE 104-9.99734.432 -24.9361.0024.04OATOM4637NGLNE 105.-12.01033.645 -25.5491.00 27.29NATOM4638CAGLNE 105-12.22434.777 -26.4721.0028.79CATOM4639CBGLNE 105-12.50934.323 -27.9041.0029.78CATOM4640CGGLNE 105-11.58835.020 -28.9501.00 35.55CATOM4641CDGLNE 105-10.33434.200 -29.2671.00 39.60CATOM4642OEl GLNE 105-9.70433.603 -28.3651.0043.90OATOM4643NE2 GLNE 105-9.97934.142-30.5531.0038.71NATOM4644CGLNE 105-13.31135.722 -25.9561.00 28.27CATOM4645OGLNE 105 ■-14.47735.363 -25.8921.00 26.86OATOM4646NGLUE 106 ■■12.90036.920 -25.5461.00 28.56NATOM4647CAGLUE 106-13.81837.920 -25.0431.0029.48CATOM4648CBGLUE 106-13.05939.128 -24.4981.00 29.57CATOM4649CGGLUE 106-13.96540.218-23.9851.00 30.21CATOM4650CDGLUE 106-13.22341.533 -23.8051.00 33.86CATOM4651OEIGLUEIO6-12.59541.692-22.7271.00 33.27OATOM4652OE2 GLUE 106-13.27542.400 -24.7341.00 34.52OATOM4653CGLUE 106-14.78638.379-26.1241.0029.33CATOM4654OGLUE 106-■14.36039.015-27.0821.00 30.12OATOM4655NVALE 107-16.07738.080-25.9571.00 28.08NATOM4656CAVALE 107-■17.11838.488 -26.9131.00 26.97CATOM4657CBVALE 107-■18.18237.349 -27.0731.00 27.17CATOM4658CGl VALE 107-19.48037.887-27.6771.00 27.73CATOM4659CG2VALE107-17.62436.209-27.8871.00 27.10C[0347]
ATOM4704CAPROE 113-21.58746.743-11.8711.00 28.00CATOM4705CBPROE 113-21.89445.414-11.1491.0028.55CATOM4706CGPROE 113-20.79044.475-11.4761.00 28.61CATOM4707CDPROE 113-19.73245.176-12.2421.00 26.56CATOM4708CPROE 113-21.46347.865 -10.8481.0028.70CATOM4709OPROE 113-20.41747.987 -10.1621.00 28.42OATOM4710NARGE 114-22.47548.715--10.6891.0028.78NATOM4711CAARGE 114-23.65948.882-11.4761.0029.06CATOM4712CBARGE 114-24.16547.596-12.2141.0029.08CATOM4713CGARGE 114-25.16147.871-13.2891.0026.73CATOM4714CDARGE 114-25.93846.585-13.7841.00 31.30CATOM4715NEARGE 114-27.22046.898-14.4641.0037.09NATOM4716CZARGE 114-27.38547.757-15.4961.00 37.27CATOM4717NHl ARG E 114-26.36848.441 -■15.9891.00 37.33NATOM4718NH2ARGE 114-28.59247.951 ■■16.0411.00 40.51NATOM4719CARGE 114-24.72049.375 -10.5031.00 27.86CATOM4720OARGE 114-25.36850.390-10.7811.0027.85OATOM4721NPROE 115-24.89548.663-9.3601.00 27.04NATOM4722CAPROE 115-26.25648.609-8.8391.0026.27CATOM4723CBPROE 115-26.21347.391-7.9411.0026.21CATOM4724CGPROE 115-24.81247.521-7.3341.0025.63CATOM4725CDPROE 115-23.96547.906-8.4971.0026.53CATOM4726CPROE 115-26.66249.847-8.0491.00 26.53CATOM4727OPRO E 115-25.81350.472-7.3261.00 25.60OATOM4728NTHRE 116-27.93750.194-8.2551.00 24.81NATOM4729CATHRTE 116-28.72851.167-7.5061.00 24.84CATOM4730CBTHRE 116-28.88952.545-8.2381.0025.49CATOM4731OGl THRE 116-29.57752.383-9.4991.0027.32OATOM4732CG2THRE 116-27.55153.251-8.4601.0024.88CATOM4733CTHRE 116-30.13550.557-7.3461.00 24.78CATOM4734OTHHE 116-30.47149.543-8.0181.00 23.86OATOM4735NMETE 117-30.94651.165-6.4581.00 24.26NATOM4736CAMETE 117-32.36750.801-6.2671.0023.98CATOM4737CBMETE 117-33.13150.951-7.5811.0024.10CATOM4738CGMETE 117-33.11552.390-8.1021.0023.32CATOM4739SDMETE 117-34.01352.706-9.5921.0026.09SATOM4740CEMETE 117-32.96552.187--10.9651.0023.19CATOM4741CMETE 117-32.56849.389-5.7341.00 23.34CATOM4742OMETE 117-33.48548.671-6.1601.00 22.16OATOM4743NGLYE 118-31.68949.005-4.8131.0021.53NATOM4744CAGLYE 118-31.72947.696-4.1611.00 20.22CATOM4745CGLYE 118-30.56546.807-4.5371.0019.96CATOM4746OGLYE 118-29.82847.114-5.4721.00 20.63OATOM4747NILEE 119-30.459 45.685 ■-3.8291.0020.57N[0349]ATOM4748CAILEE 119-29.45244.656-4.0051.00 20.88CATOM4749CBILEE 119-29.45543.665-2.8131.00 20.79CATOM4750CGl ILEE 119-29.30544.394-1.4651.0020.53CATOM4751CDl ILEE 119-29.54143.539-0.2621.0020.55CATOM4752CG2ILE E 119-28.25142.722-2.9291.0019.64CATOM4753CILEE 119-29.66043.918-5.3391.0022.28CATOM4754OILEE 119-30.77643.486-5.6331.0022.05OATOM4755NHIS E 120 -28.59543.825-6.1531.0022.28NATOM4756CAHIS E 120-28.65443.106-7.4251.0021.40CATOM4757CBHIS E 120-28.03443.879-8.6021.0021.13CATOM4758CGHISE 120 -28.68245.195-8.9091.0018.51CATOM4759NDl HIS E 120 -28.63545.760 -10.1641.00 20.47NATOM4760CEl HIS E 120-29.23146.934-10.1421.00 17.75CATOM4761NE2HISE120 -29.66147.155-8.9151.00 15.91NATOM4762CD2 HIS E 120 -29.32046.087-8.1231.0016.23CATOM4763CHIS E 120 -27.83441.879-7.2701.0021.80CATOM4764OHIS E 120 -26.79341.882-6.5591.0021.37OATOM4765NARGE 121-28.26840.839-7.9741.00 20.88NATOM4766CAARGE 121 -27.46039.644-8.1541.0022.18CATOM4767CBARGE 121 -28.29538.372-8.0901.00 22.14CATOM4768CGARG E 121-29.17838.219'-6.8571.0021.36CATOM4769CDARGE 121 -30.31737.153-7.2041.0023.23CATOM4770NEARGE 121 -31.35837.759-8.0201.0024.48NATOM4771CZARG E 121 -32.33937.115-8.6691.00 23.99CATOM4772NHl ARGE 121-32.44935.804-8.6431.00 22.31NATOM4773NH2ARGE 121-33.20437.806-9.3801.0021.77NATOM4774CARGE 121-26.64839.656-9.4411.0022.73CATOM4775OARGE 121 -27.21239.790-10.5361.0022.59OATOM4776NLEU E 122-25.31939.491-9.2961.00 23.17NATOM4777CALEUE 122 -24.42439.201-10.4431.0022.68CATOM4778CBLEUE 122 -23.14340.038-10.3951.0023.15CATOM4779CGLEU E 122-23.29141.565-10.5021.0023.13CATOM4780CDl LEUE 122 -23.94542.021 -11.8181.0019.58CATOM4781CD2 LEU E 122-23.96542.280-9.2851.00 23.81CATOM4782CLEUE 122-24.13937.701 -10.6041.0021.74CATOM4783OLEU E 122 -23.52937.059-9.7591.00 20.62OATOM4784NVALE 123 -24.66137.152-11.7061.00 21.83NATOM4785CAVALE 123 -24.72935.702-11.9441.0020.33CATOM4786CBVALE 123 -26.16435.217-12.5451.0020.73CATOM4787CGl VAL E 123 -26.22233.718-12.6181.0017.01CATOM4788CG2VALE 123 -27.33135.674 -11.6891.00 20.22CATOM4789CVALE 123 -23.63035.338-12.9351.0019.74CATOM4790OVALE 123 -23.36936.073 -13.8661.00 20.19OATOM4791NPHEE 124 -22.96334.219-12.7051.0020.47N[0350]
[0353]ATOM4880CBTHRE 134-18.46532.078 -35.3701.00 48.47ATOM4881OGl THRE 134-17.26231.664-36.0271.0048.15ATOM4882CG2 THR E 134-18.52333.591 -35.3771.0047.80ATOM4883CTHRE 134-19.71431.984 -33.1171.0048.35ATOM4884OTHRE 134-20.87331.667 -33.4381.0046.97ATOM4885NVALE 135-19.43132.726 -32.0471.00 48.39ATOM4886CAVAL E 135-20.46133.458 -31.3161.0048.63ATOM4887CBVALE 135-20.42033.183 -29.7811.0048.37ATOM4888CGl VALE 135-21.41734.062 -29.0211.00 47.14ATOM4889CG2VALE 135-20.70731.712-29.5031.00 48.36ATOM4890CVALE 135-20.39434.962-31.6541.00 49.23ΑΓΟΜ4891OVALE 135-19.35135.627-31.4891.0049.20ATOM4892NTYRE 136-21.51335.474-32.1611.0049.56ATOM4893CATYRE 136-21.66736.905 -32.3971.00 50.30ATOM4894CBTYRE 136-22.66137.174-33.5471.00 51.67ATOM4895CGTYRE 136-22.38436.345 -34.7971.00 53.32ATOM4896CDl TYRE 136-23.07135.147 -35.0251.00 54.89ATOM4897CEl TYRE 136-22.80934.369 -36.1601.00 54.80ATOM4898CZTYRE 136-21.84734.795 -37.0731.00 54.79ATOM4899OHTYR R 136-21.60734.026 -38.1991.00 55.41ATOM4900CE2 TYRE 136-21.14835.980 -36.8671.00 54.26ATOM4901CD2 TYR E 136-21.41636.744 -35.7351.00 54.28ATOM4902CTYRE 136-22.07637.617-31.0941.00 49.47ATOM4903OTYRE 136-22.80237.063 -30.2561.00 49.41ATOM4904NALAE 137 -21.56038.825 -30.9091.0048.38ATOM4905CAALAE 137-21.87739.599 -29.7331.0047.22ATOM4906CBALAE 137-20.90940.738 -29.5801.0047.00ATOM4907CALAE 137 -23.28540.113-29.9061.00 46.63ATOM4908OALAE 137-23.60440.649 -30.9681.0047.13ATOM4909NPRO E 138-24.16239.903 -28.8941.00 45.86ATOM4910CAPRO E 138-25.42040.653 -28.8701.0044.56ATOM4911CBPROE 138-25.83840.545 -27.4111.00 43.93ATOM4912CGPROE 138-25.43539.177 -27.0611.0044.39ATOM4913CDPROE 138-24.08738.979 -27.7451.0045.70ATOM4914CPRO E 138-25.24142.126 -29.2901.00 43.95ATOM4915OPROE 138-24.16842.733 -29.0641.0043.05ATOM4916NGLYE 139-26.27642.679 -29.9191.00 42.83ATOM4917CAGLYE 139-26.23844.076 -30.3761.0042.11ATOM4918CGLYE 139-26.35845.097-29.2521.00 40.96ATOM4919OGLYE 139-26.15046.303 -29.4671.00 41.39ATOM4920NTRPE 140 -26.67344.599 -28.0601.00 39.17ATOM4921CATRPE 140 -26.99645.409 -26.8911.00 38.13ATOM4922CBTRPE 140 -28.40446.054 -27.0091.00 39.23ATOM4923CGTRPE 140 -29.56545.096 -27.3771.0040.35COCCONCCCCCONCCOCONCCCONCCCCCONCCONC137ATOM4924CDl TRPE 140-30.34844.361 -26.5101.0042.17CATOM4925NEl TRPE 140 -31.27743.619-27.2211.0041.48NATOM4926CE2 TRPE 140 -31.13343.893 -28.5571.00 41.43CATOM4927CD2TRPE 140 -30.07244.817-28.6991.0040.92CATOM4928CE3 TRPE 140 -29.72045.256 -29.9901.00 41.21CATOM4929CZ3 TRPE 140 -30.42444.771 -31.0861.00 42.20CATOM4930CH2TRPE140 -31.49143.856 -30.9181.0042.05CATOM4931CZ2TRPE 140 -31.85943.409 -29.6631.0043.60CATOM4932CTRPE 140-26.91944.498 -25.6781.00 35.85CATOM4933OTRPE 140 -26.91143.288 -25.823t.00 35.27OATOM4934NARGE 141 -26.88345.076-24.4821.00 33.21NATOM4935CAARGE 141 -26.70644.281 -23.2601.00 30.83CATOM4936CBARG E 141 -25.62044.908 -22.3781.00 29.17CATOM4937CGARGE 141 -24.27745.063 -23.0641.00 27.20CATOM4938CDARGE 141 -23.34045.866 -22.1511.00 24.78CATOM4939NEARGE 141 -21.95745.897 -22.6201.00 23.90NATOM4940CZARGE 141 -20.98945.058 -22.2541.00 24.75CATOM4941NH1ARGE 141-19.76945.218-22.7551.0026.31NATOM4942NH2ARGE 141 -21.21744.080-21.3771.0024.08NATOM4943CARGE 141 -28.00644.079 -22.4541.00 30.13CATOM4944OARGE 141-28.13743.101 -21.7281.00 30.28OATOM4945NGLNE 142 -28.93345.028 -22.5531.00 29.94NATOM4946CAGLN E 142 -30.22444.950-21.8631.00 30.38CATOM4947CBGLNE 142 -31.02346.250 -21.9741.00 31.27CATOM4948CGGLNE 142-30.24947.502 -22.3631.00 34.89CATOM4949CDGLNE 142 -30.00147.565 -23.8461.00 38.29CATOM4950OEl GLNE 142-29.02547.001 -24.3451.0041.33OATOM4951NE2 GLN E 142-30.87448.243 -24.5621.00 39.72NATOM4952CGLNE 142-31.04043.867 -22.5461.00 29.37CATOM4953OGLNE 142-30.85743.611 -23.7271.0028.63OATOM4954NASNE 143 -31.86943.201 -21.7661.0028.77NATOM4955CAASNE 143 -32.88242.290 -22.2841.0029.32CATOM4956CBASNE 143 -33.94343.101 -23.0721.0029.38CATOM4957CGASNE 143 -34.48144.267 -22.2211.0028.29CATOM4958ODl ASNE 143 -34.92644.051 -21.1031.00 26.35OATOM4959ND2ASNE143 -34.35745.482 -22.7031.00 28.72NATOM4960CASNE 143 -32.31041.032-22.9631.00 29.36CATOM4961OASNE 143 -32.95840.408 -23.8281.00 29.37OATOM4962NPHE E 144-31.11340.650 -22.4801.00 28.64NATOM4963CAPHEE 144-30.41939.381 -22.7771.0027.63CATOM4964CBPHE E 144-28.98039.424 -22.1861.00 26.44CATOM4965CGPHEE 144-28.11238.250 -22.5581.0024.53CATOM4966CDl PHE E 144-27.48138.182 -23.7961.00 25.41CATOM4967CEl PHH E 144 -26.65237.075 -24.1191.00 23.63C[0354]ATOM4968CZPHE E 144-26.48036.038 -23.2021.00 23.32CATOM4969CE2 PtIE E 144-27.12136.103 -21.9951.0022.89CATOM4970CD2PHEE 144-27.92237.206-21.6751.0022.41CATOM4971CPHEE 144-31.16338.247 -22.1241.0027.45CATOM4972OPHEE 144-31.73838.403 -21.0531.0028.43OATOM4973NASN E 145 -31.14837.096 -22.7641.0028.39NATOM4974CAASNE 145-31.79535.888 -22.2191.0028.33CATOM4975CBASNE 145 -33.11935.572 -22.9701.0027.72CATOM4976CGASNE 145 -33.89034.429-22.3171.0023.30CATOM4977ODl ASN E 145 -33.51433.298 -22.4351.0025.28OATOM4978ND2ASNE 145 -34.89634.750 -21.5361.0023.24NATOM4979CASNE 145 -30.82434.717-22.3451.00 29.00CATOM4980OASNE 145 -30.50834.280 -23.4581.0030.93OATOM4981NTHRE 146 -30.38234.185 -21.2161.0029.58NATOM4982CATHRE 146 -29.34933.139-21.1931.00 29.62CATOM4983CBTHRE 146 -28.79432.945-19.7621.0028.93CATOM4984OGl THRE 146-28.05434.105-19.3901.0030.05OATOM4985CG2THRE 146 -27.85831.780-19.6861.00 30.16CATOM4986CTHRE 146 -29.84131.810-21.8021.00 30.18CATOM4987OTHRE 146 -29.09031.108 -22.4971.0028.70OATOM4988NLYS E 147 -31.10231.486 -21.5201.00 30.69NATOM4989CALYSE 147 -31.75630.308 -22.0941.00 31.21CATOM4990CBLYSE 147 -33.20130.128-21.5711.00 30.76CATOM4991CGLYS E 147 -33.34629.542-20.1391.00 32.42CATOM4992CDLYS E 147 -34.82729.046-19.9271.00 31.96CATOM4993CELYS E 147 -35.38329.195-18.4681.00 31.92CATOM4994NZLYSE 147 -36.13630.472-18.0591.00 31.81NATOM.4995CLYS E 147 -31.76930.400 -23.6101.00 30.02CATOM4996OLYS E 147 -31.39929.465 -24.2521.0029.69OATOM4997NASPE 148 -32.21731.525 -24.1591.00 30.78NATOM4998CAASPE 148 -32.32431.715-25.6031.00 30.92CATOM4999CBASPE 148 -32.85833.111 -25.9601.00 30.35CATOM5000CGASPE 148 -34.32733.325 -25.6101.00 31.75CATOM5001ODl ASP E 148 -35.01032.438 -25.0391.00 35.85OATOM5002OD2ASPE148 -34.80034.436 -25.8951.00 29.59OATOM5003CASPE 148 -30.95831.619-26.2271.00 31.56CATOM5004OASPE 148 -30.81031.088-27.3331.00 33.29OATOM5005NPHEE 149-29.96532.180-25.5391.0031.13NATOM5006CAPHEE 149 -28.61332.224-26.0311.00 31.08CATOM5007CBPHEE 149 -27.83033.181 -25.1301.00 30.86CATOM5008CGPIIEE 149 -26.38433.256 -25.4421.00 31.05CATOM5009CDl PHE E 149-25.90634.206 -26.3421.0029.88CATOM5010CEl PHEE 149 -24.54834.298 -26.6161.0031.18CATOM5011CZPHEE 149 -23.64533.438 -25.9891.00 32.00C[0355]ATOM5100NVALE 162 -22.68330.479 -10.3301.0024.81NATOM5101CAVALE 162 -22.55731.037-8.9901.0023.58CATOM5102CBVALE 162-21.05130.882-8.4421.00 24.07CATOM5103CGl VALE 162-20.12131.946-9.0481.00 22.69CATOM5104CG2 VALE] 62-20.95130.868-6.9001.00 21.64CATOM5105CVALE 162-22.99032.499-9.1131.0023.07CATOM5106OVALE 162-22.79533.122-10.1601.0021.70OATOM5107NTYR E 163 -23.56933.051-8.0521.00 22.88NATOM5108CATYRE 163 -23.85834.494-8.0161.00 22.63CATOM5109CBTYRE 163 -25.35334.719-8.1781.00 21.91CATOM5110CGTYRE 163 -26.12634.431-6.9251.00 23.26CATOM5111CDl TYRE 163 -26.63335.475-6.1651.00 22.45CATOM5112CEl TYRE 163 -27.33435.238-5.0311.0018.41CATOM5113CZTYRE 163 -27.51033.972-4.6091.00 19.51CATOM5114OHTYRE 163 -28.23533.802-3.4521.0022.62OATOM5115CE2TYRE163 -27.02332.899-5.3251.00 19.30CATOM5116CD2TYRE163 -26.34533.132-6.4891.00 20.53CATOM5117CTYRE 163 -23.28935.218-6.7581.0022.02CATOM5118OTYRE 163 -23.07834.582-5.7021.00 22.48OATOM5119NPHEE 164-23.01736.520-6.8861.0020.74NATOM5120CAPHEE 164-22.85137.386-5.6901.00 19.54CATOM5121CBPHE E 164-21.40637.954-5.5041.00 18.27CATOM5122CGPHEE 164-20.99338.969-6.5261.00 15.93CATOM5123CDl PHEE 164-20.26438.576-7.6541.0013.10CATOM5124CEl PHEE 164-19.89539.503-8.5961.0010.51CATOM5125CZPHEE 164-20.18840.873-8.4331.00 14.39CATOM5126CE2 PHE E 164-20.89241.303-7.2731.00 9.47CATOM5127CD2PHEE 164-21.27940.329-6.3441.0015.33CATOM5128CPHEE 164-23.87438.479-5.6871.0019.26CATOM5129OPHEE 164-24.40738.826-6.7351.0018.92OATOM5130NASN E 165 -24.15939.001-4.4881.0019.02NATOM5131CAASNE 165 -24.98940.191-4.2751.00 18.63CATOM5132CBASNE 165 -25.84539.992-3.0181.00 17.67CATOM5133CGASNE 165 -26.94638.933-3.2191.0017.36CATOM5134ODl ASN E 165 -27.14638.051-2.3921.0018.92OATOM5135ND2ASNE165 -27.62239.012-4.3361.0012.57NATOM5136CASNE 165 -24.20641.494-4.1721.0021.69CATOM5137OASNE 165 -23.15841.566-3.4571.0020.76OATOM5138NSERE 166 -24.71742.535-4.8421.0023.59NATOM5139CASERE 166 -24.09543.874-4.7381.00 25.59CATOM5140CBSERE 166 -23.15644.112-5.9261.00 25.27CATOM5141OGSERE 166 -22.17945.100-5.6261.00 22.18OATOM5142CSERE 166-25.14544.998-4.6301.0026.74CATOM5143OSERE 166 -26.23744.879-5.1521.0027.38O[0358]vATOM5144NGLNE 167 -24.82346.067-3.9121.0027.98NATOM5145CAGLNE 167 -25.70347.214-3.8021.00 29.03CATOM5146CBGLNE 167 -26.65047.100-2.5981.0028.36CATOM5147CGGLNE 167-25.98246.980-1.2301.00 30.57CATOM5148CDGLN E 167 -26.98346.788-0.1001.00 29.45CATOM5149OEl GLNE 167-27.96847.498-0.0091.00 32.08〇ATOM5150NE2GLNE 167 -26.74545.8060.7381.00 32.88NATOM5151CGLNE 167 -24.89048.520-3.7701.0029.70CATOM5152〇GLNE 167 -23.70548.493-3.5071.0029.56OATOM5153NARGE 168 -25.53949.640-4.0891.00 30.48NATOM5154CAARGE 168 -24.94350.959-4.0311.00 32.33CATOM5155CBARGE 168 -26.08351.971-4.1011.00 31.55CATOM5156CGARGE 168 -25.74253.421-4.2141.00 32.46CATOM5157CDARG E 168 -27.02054.340-4.2321.00 33.32CATOM5158NEARGE 168 -27.95954.114-3.1221.00 34.06NATOM5159CZARGE 168 -27.75254.530-1.8741.00 34.83CATOM5160NHl ARG E 168 -26.62255.187-1.5541.00 34.71NATOM5161NH2ARGE 168 -28.65054.268-0.9331.00 30.85NATOM5162CARG E 168 -24.20151.079-2.6911.00 33.81CATOM5163OARG E 168 -24.74450.712-1.6501.00 33.62OATOM5164NGLUE 169 -22.97551.597-2.7201.00 36.35NATOM5165CAGLUE 169-22.17451.826-1.4781.00 39.21CATOM5166CBGLU E 169 -20.70151.960-1.8251.00 39.33CATOM5167CGGLUE 169-20.23950.824-2.7011.0041.98CATOM5168CDGLUE 169-18.73650.781-2.9221.0045.43CATOM5169OEl GLUE 169-17.93551.318-2.1081.00 45.27OATOM5170OE2 GLUE 169-18.37550.181-3.9441.0046.67OATOM5171CGLUE 169-22.60453.072-0.7451.00 40.36CATOM5172OGLUE 169 -22.52354.150-1.3011.00 40.77OATOM5173NALAE 170 -23.05652.9180.5051.00 43.17NATOM5174CAALAE 170 -23.73953.9981.2461.00 44.84CATOM5175CBALAE 170 -24.86453.4262.1341.0044.99CATOM5176CALAE 170-22.79754.8752.0781.00 46.12CATOM5177OALAE 170 -23.27455.7772.7851.0046.89OATOM5178OXTALAE 170 -21.55854.7242.0541.00 46.97OTERATOM5179NGLYF 2-29.7244.80925.4131.00 63.75NATOM5180CAGLYF 2-29.0234.72224.0921.00 63.70CATOM5181CGLYF 2 -27.6245.32624.1501.00 63.79CATOM5182OGLYF 2-27.4796.56324.1771.00 63.85OATOM5183NPROF 3 -26.5794.46224.1981.00 63,30NATOM5184CAPROF 3-25.1504.87324.2031.00 62.76CATOM5185CBPROF 3 -24.4313.63924.7981.00 62.92CATOM5186CGPROF 3 -25.5502.68325.2811.00 62.81C[0359]143ATOM5187CDPROF3 -26.7143.00624.3881.00 63.39CATOM5188CPROF3 -24.3635.43122.9571.00 61.90CATOM5189OPROF3 -23.4386.18923.2161.00 61.62OATOM5190NGLYF4 -24.7015.18821.6731.00 61.30NATOM5191CAGLYF4 -26.0394.84121.1621.00 60.57CATOM5192CGLYF4-26.2183.94319.9341.00 60.64CATOM5193OGLYF4 -27.2693.29919.8241.00 60.82OATOM5194NHISF5 -25.2493.93719.0021.00 59.99NATOM5195CAHISF5 -25.0772.88917.9191.00 59.77CATOM5196CBHISF5 -25.4821.45818.3651.00 59.41CATOM5197CGHISF5 -24.3260.51318.5361.00 58.21CATOM5198NDl HIS F5 -23.3070.72519.4401.00 56.39NATOM5199CEl HIS F5 -22.442-0.26719.3671.00 54.62CATOM5200NE2 HIS F5 -22.873-1.12618.4651.00 54.03NATOM5201CD2 HIS F5 -24.048-0.66517.9331.00 55.73CATOM5202CHISF5 -25.5233.21616.4491.00 59.58CATOM5203OHISF5-24.7103.74415.6781.00 59.85OATOM5204NARGF6 -26.7252.83316.0001.00 58.61NATOM5205CAARGF6 -27.6041.86716.6211.00 57.77CATOM5206CBARGF6 -28.6272.57017.5191.00 58.10CATOM5207CGARGF6 -29.8421.71917.9311.00 60.49CATOM5208CDARGF6 -29.5030.55718.8821.00 62.43CATOM5209NEARGF6 -29.6050.97420.2821.0064.52NATOM5210CZARGF6 -29.3770.18321.3271.00 64.71CATOM5211NHl ARG F6 -29.020-1.08621.1351.00 64.67NATOM5212NH2ARGF6-29.5170.66622.5641.00 63.17NATOM5213CARGF6-28.3161.11515.5051.00 56.67CATOM5214OARGF6 -28.5051.65514.4201.00 56.94OATOM5215NASPF7 -28.608-0.15715.7631.00 55.18NATOM5216CAASPF7-29.804-0.85515.2621.00 53.84CATOM5217CBASPF7 -30.9550.11415.0001.00 54.28CATOM5218CGASPF7-32.271-0.41015.5191.00 55.23CATOM5219ODl ASPF7 -32.9530.32516.2571.00 56.48OATOM5220OD2ASPF7 -32.620-1.56415.2001.00 57.39OATOM5221CASPF7 -29.624-1.81514.0931.00 52.41CATOM5222OASPF7 -29.790-3.03714.2311.00 52.26OATOM5223NARGF8 -29.333-1.25312.9341.00 50.53NATOM5224CAARGF8 -28.925-2.05911.8091.0048.55CATOM5225CBARGF8 -29.470-1.47310.5121.00 49.09CATOM5226CGARGF8 -28.930-0.10510.1731.00 50.55CATOM5227CDARGF8 -29.8610.5979.2421.00 54.33CATOM5228NEARGF8 -29.6982.0379.3501.00 57.72NATOM5229CZARGF8 -30.6042.9288.9611.00 59.33CATOM5230NHl ARG F8 -30.3454.2299.1151.00 59.07N[0360]144ATOM5231NH2ARGF8-31.7612.5198.4311.00 59.38NATOM5232CARGF8 -27.400-2.10911.8041.00 46.68CATOM5233OARGF8 -26.790-2.48510.8061.0045.93OATOM5234NASPF9 -26.799-1.69812.9241.00 44.75NATOM5235CAASPF9 -25.378-1.89713.1681.0042.92CATOM5236CBASPF9 -24.968-1.27214.5041.0042.91CATOM5237CGASPF9 -23.470-1.01414.6021.00 42.53CATOM5238ODl ASPF9 -23.0920.17014.6501.00 43.38OATOM5239OD2ASPF9 -22.666-1.97014.6161.00 39.13OATOM5240CASPF9-25.171-3.40713.1841.0041.81CATOM5241OASPF9 -25.955-4.12913.7971.00 41.57OATOM5242NPROF10-24.153-3.89712.4541.0040.99NATOM5243CAPROF10-23.848-5.33312.3911.0040.22CATOM5244CBPROF10-22.553-5.38111.5741.0040.13CATOM5245CGPROF10-22.563-4.13810.7691.00 40.95CATOM5246CDPROF10-23.225-3.10211.6251.00 41.08CATOM5247CPROF10-23.656-6.00513.7741.00 39.56CATOM5248OPROF10-23.968-7.19013.9231.00 39.57OATOM5249NLEUF11 -23.156-5.26114.7641.00 38.51NATOM5250CALEUF11-23.017-5.78316.1111.00 37.76CATOM5251CBLEUF11 -22.205-4.83917.0061.00 37.33CATOM5252CGLEUF11 -20.716-4.61416.7081.00 36.56CATOM5253CDl LEUF11 -20.135-3.57817.6501.00 33.95CATOM5254CD2 LEUF11-19.940-5.92716.7661.00 36.44CATOM5255CLEUF11 -24.378-6.01816.7321.00 37.67CATOM5256OLEUF11-24.575-7.02517.4091.00 37.86OATOM5257NVALF12-25.306-5.07916.5281.00 37.67NATOM5258CAVALF12-26.675-5.21417.0401.00 37.48CATOM5259CBVALF12-27.480-3.87517.0231.00 37.75CATOM5260CGlVALF12 -26.737-2.78117.8201.00 36.68CATOM5261CG2VALF12 -28.890-4.07717.5821.00 36.18CATOM5262CVALF12-27.411-6.35116.3211.00 37.59CATOM5263OVALF12 -28.085-7.14816.9631.00 37.80OATOM5264NVALF13-27.213-6.46215.0121.00 37.90NATOM5265CAVALF13 -27.824-7.52414.2211.00 38.08CATOM5266CBVALF13 -27.669-7.26912.6901.00 38.41CATOM5267CGl VALF13 -28.363-8.35611.8781.00 38.10CATOM5268CG2VALF13 -28.257-5.93612.3141.00 37.57CATOM5269CVALF13 -27.249-8.88514.5851.00 38.89CATOM5270OVALF13 -27.962-9.89414.5401.00 39.09OATOM5271NGLYF14 -25.959-8.91114.9391.00 38.86NAlOM5272CAGLYF14 -25.276-10.15015.3001.00 38.10CATOM5273CGLYF14-25.511 -10.46616.7571.00 38.24CATOM5274OGLYF14 -25.082 -11.51217.2491.00 38.44O[0361]
ATOM5319NLEUF21 -22.463-6.90024.9791.00 33.38NATOM5320CALEUF21 -22.210-5.45625.1221.00 32.94CATOM5321CBLEUF21 -21.277-4.97023.9881.00 32.51CATOM5322CGLEUF21 -19.944-5.68923.8111.00 32.51CATOM5323CDl LEUF21-19.346-5.37622.4631.00 32.77CATOM5324CD2 LEU F21 -18.973-5.30624.9791.00 33.26CATOM5325CLEUF21 -23.489-4.62525.1021.00 33.17CATOM5326OLEUF21 -24.520-5.04824.5131.00 31.76OATOM5327NASPF22 -23.396-3.44525.7261.00 33.46NATOM5328CAASPF22 -24.334-2.32725.4801.00 34.36CATOM5329CBASPF22 -24.485-1.41826.7041.00 34.12CATOM5330CGASPF22 -24.978-2.15427.9351.00 34.00CATOM5331ODl ASP F22 -25.860-3.00627.7991.00 31.87OATOM5332OD2ASPF22 -24.490-1.86829.0461.00 34.03OATOM5333CASPF22 -23.794-1.49324.3381.0035.14CATOM5334OASPF22 -22.579-1.45024.1221.00 35.43OATOM5335NALAF23 -24.691-0.83723.5971.00 35.91NATOM5336CAALAF23 -24.2980.10822.5511.00 35.88CATOM5337CBALAF23 -25.5050.84422.0011.00 35.34CATOM5338CALAF23 -23.2271.09023.0541.00 36.51CATOM5339OALAF23 -23.1331.39324.2561.00 37.41OATOM5340NPHEF24 -22.3891.54122.1301.00 36.18NATOM5341CAPHEF24 -21.2642.39622.4341.00 36.26CATOM5342CBPHEF24-20.0711.55522.9721.00 36.37CATOM5343CGPHEF24-19.3930.71421.9201.00 35.11CATOM5344CDl PI-IEF24-19.828-0.57021.6531.00 34.52CATOM5345CElPHEF24-19.217-1.33020.6831.00 34.82CATOM5346CZPIIEF24-18.157-0.79919.9601.00 35.77CATOM5347CE2 PHE F24-17.7110.48020.2211.00 33.91CATOM5348CD2PHEF24-18.3221.22121.1961.00 34.72CATOM5349CPHEF24 -20.9353.08921.1121.00 36.63CATOM5350OPI-IEF24 -21.3932.67120.0451.00 35.77OΑΓΟΜ5351NVALF25 -20.1534.15021.1761.00 37.45NATOM5352CAVALF25-19.6784.78219.9501.00 38.11CATOM5353CBVALF25-19.7206.33120.0651.00 38.70CATOM5354CGlVALF25 -19.0076.77821.3281.00 39.79CATOM5355CG2VALF25-19.1107.00518.8251.00 39.10CATOM5356CVALF25-18.2634.26419.6371.00 37.81CATOM5357OVALF25 -17.3444.34520.4881.00 36.99OATOM5358NARGF26-18.1083.70418.4381.00 36.94NATOM5359CAARGF26-16.7953.28717.9461.00 37.22CATOM5360CBARGF26-16.8872.63616.5651.00 36.52CATOM5361CGARGF26-17.6031.30416.5061.00 36.82CATOM5362CDARGF26-17.7300.89915.0651.00 35.12C[0363]
ATOM5407NVALF32-8.482-6.95413.0541.00 28.43NATOM5408CAVALF32-8.202-8.33013.3651.00 27.67CATOM5409CBVALF32-9.352-8.99814.2001.00 27.65CATOM5410CGl VALF32-8.965-10.40314.6201.00 27.22CATOM5411CG2VALF32-9.676-8.17315.4231.00 26.06CATOM5412CVALF32-7.935-9.10512.0881.0028.83CATOM5413OVALF32-8.828-9.25511.2141.00 29.34OATOM5414NTHRF33-6.714-9.62812.0031.0028.66NATOM5415CATHRF33-6.260-10.40310.8531.0028.67CATOM5416CBTHRF33-5.387-9.5539.9441.0028.87CATOM5417OGl THRF33-5.987-8.2489.8141.0026.81OATOM5418CG2THRF33-5.212-10.1958.5861.00 28.73CATOM5419CTHRF33-5.576--11.73111.2581.0028.85CATOM5420OTHRF33-4.572 ■-11.75412.0111.0027.53OATOM5421NTYRF34-6.200.-12.80910.7671.00 28.38NATOM5422CATYRF34-5.722-14.19310.7971.0029.48CATOM5423CBTYRF34-6.929-15.15210.9321.0029.30CATOM5424CGTYRF34-7.510-15.23912.3191.0028.64CATOM5425CDl TYRF34-6.891 ■-15.99913.2911.00 30.47CATOM5426CEl TYRF34-7.399 -16.08014.5901.0031.51CATOM5427CZTYRF34-8.542-15.39214.9351.00 30.51CATOM5428OHTYRF34-9.036-15.51116.2221.00 27.71OATOM5429CE2TYRF34-9.192-14.61413.9701.00 31.35CATOM5430CD2TYRF34-8.662 -■14.53912.6651.00 29.09CATOM5431CTYRF34-5.005 -14.5179.4901.00 30.11CATOM5432OTYRF34-5.660 --14.8048.4971.00 29.48OATOM5433NGLYF35-3.676 -14.4789.4921.00 30.65NATOM5434CAGLYF35-2.894-14.5858.2581.00 32.03CATOM5435CGLYF35-3.034-13.3287.4141.00 33.72CATOM5436OGLYF35-2.588 -12.2427.8101.00 33.55OATOM5437NSERF36-3.668 -13.4526.2441.0035.02NATOM5438CASERF36-4.033.-12.2375.4801.00 37.13CATOM5439CDSERF36-3.259--12.1304.1661.00 37.16CATOM5440OGSERF36-3.632-13.1723.2861.00 39.94OATOM5441CSERF36-5.547 -12.1005.2431.00 37.84CATOM5442OSERF36-5.968 -11.4364.3021.00 38.25OATOM5443NLYSF37-6.343 -12.7266.1081.00 38.02NATOM5444CALYSF37-7.789-12.5136.1471.00 38.40CATOM5445CBLYSF37-8.542 -■13.8446.2861.00 38.67CATOM5446CGLYSF37-8.180-14.8565.2031.00 39.89CATOM5447CDLYSF37-8.648 ■•16.2765.5111.00 40.11CATOM5448CELYSF37-9.717-16.7224.5291.0043.16CATOM5449NZLYSF37-11.087-：16.2784.9331.00 45.46NATOM5450CLYSF37-8.151 -：11.5797.2921.00 37.70C[0365]ATOM5451O LYSF37 -7.941 -11.8938.465 1.00 36.92O
ATOM5452N THRF38 -8.688-10.4206.930 1.00 37.45N
ATOM5453CA THRF38 -9.131 -9.440 7.899 1.00 37.77 C
ATOM5454CB THRF38 -8.962 -8.015 7.336 1.00 38.11 C
ATOM5455OGl THRF38 -7.581 -7.8086.991 1.0040.01 O
ATOM5456CG2THRF38 -9.408 -6.9568.357 1.00 37.77 C
ATOM5457C THRF38-10.588 -9.7308.297 1.00 36.86C·
ATOM5458O THRF38-11.439 -9.9167.424 1.0037.72O
ATOM5459N VALF39-10.851 -9.7989.605 1.00 35.11N
ATOM5460CA VALF39-12.198-10.02610.144 1.00 33.90C
ATOM5461CB VALF39-12.190-10.45811.642 1.00 33.50C
ATOM5462CGl VALF39-13.584-10.51412.188 1.00 33.48C
ATOM5463CG2VALF39-11.522-11.81411.805 1.00 33.09C
ATOM5464C VALF39-13.168 -8.8499.930 1.00 33.72C
ATOM5465O VALF39-12.902 -7.70210.323 1.0032.58O
ATOM5466N SERF40 -14.291 -9.1609.281 1.00 32.60N
ATOM5467CA SERF40-15.418 -8.2529.220 1.00 33.23C
ATOM5468CB SERF40-15.802 -7.9577.782 1.0032.62C
ATOM5469OG SERF40-15.979 -9.1867.094 1.0033.84 O
ATOM5470C SERF40-16.570 -8.9239.956 1.00 33.22C
ATOM5471O SERF40-16.643-10.16210.018 1.00 33.81O
ATOM5472N ASNF41 -17.449 -8.10810.536 1.00 32.98N
ATOM5473CA ASNF41 -18.556 -8.60811.333 1.00 32.86 C
ATOM5474CB ASNF41 -19.502 -7.46811.712 1.0032.71 C
ATOM5475CG ASNF41 -18.954 -6.59012.813 1.00 33.82 C
ATOM5476ODl ASNF41 -18.974 -5.36412.701 1.0035.38O
ATOM5477ND2ASNF41 -18.515 -7.20113.909 1.00 33.16N
ATOM5478C ASNF41-19.314 -9.71810.611 1.00 33.10C
ATOM5479O ASN F41 -19.889 -9.4929.546 1.00 32.23O
ATOM5480N GLYF42-19.276-10.91711.185 1.00 33.28N
ATOM5481CA GLYF42 -20.071 -12.02310.698 1.00 34.40C
ATOM5482C GLYF42-19.338-12.9159.732 1.00 35.61C
ATOM5483O GLYF42-19.855-13.9679.383 1.00 37.07O
ATOM5484N LEUF43-18.149-12.4969.290 1.00 35.70N
ATOM5485CA LEUF43-17.319-13.2928.387 1.00 36.28C
ATOM5486CB LEUF43 -15.941 -12.6398.126 1.00 36.76C
ATOM5487CG LEUF43-14.859-13.4667.403 1.00 35.95C
ATOM5488CDl LEUF43-15.250-13.7275.941 1.00 36.28C
ATOM5489CD2LEUF43-13.509-12.8277.470 1.00 35.51C
ATOM5490C LEUF43-17.118-14.6439.019 1.0037.12C
ATOM5491O LEUF43-16.835-14.74510.218 1.00 37.52O
ATOM5492N GLUF44-17.257-15.6808.217 1.00 37.60N
ATOM5493CA GLUF44-17.106-17.0288.725 1.00 38.03C
ATOM5494CB GLUF44-18.161 -17.9558.130 1.00 38.60C
[0366]ATOM 5509¾LYSF 办6-13.027-20.945 亡宏 100 34.512: ATOM 5510 CA LYSF 私6-12.8 M-22.3 Π 9.624 1.00 35.55 O ATOM 5511 οω LYS F"仁6-12.108-23.097 8.522 1.0035.73 O ATOM 5512 no LYSF 私6-13.010-24.033 7.757 100 38.71 η ATOM 5513 CD LYSF 各6-12.506-24.251 6.329 1.0042.12 O ATOM 55M CE LYSF 46-13.481-23.636 5.323 1004307 O ATOM 5515 LYSF 払6-12.950-23.743 3.943 1.0044.38 M ATOM 5516 O LYSF 私6-I L976-22.350 lo.sl 1.00 35.60 η ATOM 5517 O LYSF 仁6-11.093-21.502 11072 100 36.44 O ATOM 5518¾PROF 47-12.260-23.313 11.808 1.0035.55 Z ATOM 5519 0> ρδρ ^ ,= 447-23.476 13009 1.0035.31 n ATOM 5520 Ow PROF 仁7-11.922-24.816 13.576 100 35.02 C ATOM 5521 CG PROF 47-13.369-24.887 13.140 1.00 35.42 O ATOM 5522 CD PROF 47-13.367-24.293 11.753 100 3506 n ATOM 5523 O PROF β -9.955-23.512 12.683 100 35,49 C ATOM 5524 O PROF 47 -9.179-22.935 Su 一oodoo一 O ATOM 5525^会-9.577—24.129 11.562 1.00 35.33¾ ATOM 5526 CA SERF 48 -8.178-24.219 loo35
ATOM 5583CD ARGF 55 0.496 -9.925 12.179 1.00 33.98 C
ATOM 5584NE ARGF 55 0.333-11.16611.430 1.0040.22N
ATOM 5585CZ ARGF 55 1.225-12.14111.319 1.00 38.11C
ATOM 5586NHl ARGF 55 2.438 -12.07911.877 1.00 38.97N
ATOM5587NH2ARGF 55 0.882-13.18210.615 1.00 39.41N
ATOM5588C ARGF 55 -3.877 -9.08914.656 1.0029.46C
ATOM5589O ARGF 55 -4.909 -9.13113.982 1.00 28.67O
ATOM5590N VALF 56 -3.717 -8.27015.693 1.00 29.01N
ATOM5591CA VALF 56 -4.727 -7.28116.092 1.00 29.31C
ATOM5592CB VALF 56 -5.443 -7.63717.417 1.0028.74C ATOM5593CGl VALF 56 -6.482 -6.57717.737 1.00 26.59C
ATOM5594CG2VALF 56 -6.074 -9.02717.345 1.00 27.74C
ATOM5595C VALF 56 -4.114 -5.88616.220 1.00 30.76C
ATOM5596O VALF 56 -3.396 -5.59117.189 1.00 31.61O
ATOM5597N GLUF 57 -4.429 -5.03315.254 1.00 32.35N
ATOM5598CA GLUF 57 -3.965 -3.64015.217 1.00 34.45C
ATOM5599CB GLUF 57 -4.033 -3.12413.806 1.0035.11C
ATOM5600CG GLUF 57 -2.760 -2.63013.308 1.0038.53C
ATOM5601CD GLUF 57 -2.093 -3.67912.473 1.0044.72C
ATOM5602OEl GLUF 57 -2.088 -3.52311.214 1.0043.89O
ATOM5603OE2GLUF 57 -1.586 -4.66313.087 1.00 49.33O
ATOM5604C GLUF 57 -4.849 -2.74016.048 1.00 34.86C
ATOM5605O GLUF 57 -6.094 -2.82415.985 1.00 33.74O
ATOM5606N VALF 58 -4.190 -1.87316.811 1.00 35.60N
ATOM5607CA VALF 58 -4.864 -0.96417.726 1.00 37.23C
ATOM5608CB VALF 58 -4.478 -1.26519.215 1.00 37.08C
ATOM5609CGl VALF 58 -5.001 -2.64719.603 1.00 37.34C
ATOM5610CG2VALF 58 -5.064 -0.24820.154 1.00 35.39C
ATOM5611C VALF 58 -4.603 0.49617.296 1.00 38.35C
ATOM5612O VALF 58 -3.468 0.86516.931 1.00 38.22O
ATOM5613N GLYF 59 -5.664 1.30517.319 1.00 38.99N
ATOM5614CA GLYF 59 -5.587 2.67316.821 1.00 40.35C
ATOM5615C GLYF 59 -5.191 3.61717.931 1.0041.42C
ATOM5616O GLYF 59 -4.320 3.29118.744 1.00 41.61O
ATOM5617N GLYF 60 -5.833 4.78017.959 1.00 42.41N
ATOM5618CA GLYF 60 -5.641 5.74419.040 1.0044.38C
ATOM5619C GLYF 60 -4.521 6.74618.818 1.00 45.28C
ATOM5620O GLYF 60 -3.715 6.60917.881 1.0045.52O
ATOM5621N ASNF 61 -4.476 7.75419.688 1.00 45.90N
ATOM5622CA ASNF 61 -3.555 8.89819.519 1.00 46.90C
ATOM5623CB ASNF 61 -3.793 10.00120.567 1.0047.31C
ATOM5624CG ASNF 61 -5.214 10.53620.571 1.00 50.87C
ATOM5625ODl ASN F 61 -5.543 11.41221.386 1.00 54.17O
ATOM5626ND2ASNF 61 -6.074 10.00819.683 1.00 53.73N
[0369]ATOM5627C ASNF61 -2.0948.493 19.573 1.0045.64CATOM5628O ASNF61 -1.3928.585 18.572 1.0045.52O
ATOM5629N ASPF62 -1.6748.029 20.751 1.0044.94N
ATOM5630CA ASPF62 -0.2707.810 21.078 1.00 44.20C
ATOM5631CB ASPF62 0.3209.068 21.746 1.00 44.51C
ATOM5632CG ASPF62 -0.3829.421 23.050 1.00 45.57C
ATOM5633ODI ASP F62 0.3009.669 24.085 1.0042.69O
ATOM5634OD2ASPF62 -1.6309.424 23.024 1.0046.73O
ATOM5635C ASPF62 -0.0666.591 21.975 1.0043.29C
ATOM5636O ASPF62 -1.0226.063 22.562 1.00 43.49O
ATOM5637N METF63 1.2006.179 22.067 1.00 41.87N
ATOM5638CA METF 63 1.675 5.034 22.837 1.00 40.93C
ATOM5639CB METF 63 3.151 4.776 22.509 1.0041.07C
ATOM5640CG METF 63 3.404 4.305 21.089 1.0041.66C
ATOM5641SD METF63 5.1254.447 20.506 1.0042.51S
ATOM5642CE METF63 4.7214.304 18.772 1.00 42.24C
ATOM5643C METF63 1.5195.133 24.359 1.00 39.75C
ATOM5644O METF63 1.7844.165 25.073 1.00 39.67O
ATOM5645N ARGF64 1.1036.288 24.860 1.00 38.97N
ATOM5646CA ARGF 64 0.905 6.458 26.303 1.00 38.39C
ATOM5647CB ARGF64 1.337 7.840 26.796 1.00 38.60C
ATOM5648CG ARGF 64 2.726 8.261 26.365 1.00 37.41C
ATOM5649CD ARGF 64 2.880 9.718 26.612 1.00 35.80C
ATOM5650NE ARGF64 2.02010.520 25.758 1.00 34.29N
ATOM5651CZ ARGF64 2.17011.833 25.586 1.00 36.44C
ATOM5652NHl ARGF64 3.18512.490 26.188 1.00 33.60N
ATOM5653NH2ARGF64 1.32812.487 24.797 1.00 32.58N
ATOM5654C ARGF64 -0.5356.220 26.675 1.00 38.04C
ATOM5655O ARGF64 -0.8866.278 27.851 1.00 37.93O
ATOM5656N THRF65 -1.3705.955 25.668 1.00 38.38N
ATOM5657CA THRF65 -2.7245.446 25.919 1.00 37.70C
ATOM5658CB THRF65 -3.7676.093 24.958 1.00 38.22C
ATOM5659OGl THRF65 -3.6917.527 25.064 1.00 39.17O
ATOM5660CG2THRF65 -5.1985.635 25.286 1.00 37.26C
ATOM5661C THRF65 -2.6743.910 25.819 1.00 36.75C
ATOM5662O THRF65 -2.2333.369 24.788 1.00 37.78O
ATOM5663N PHEF66 -3.0623.217 26.897 1.0035.29N
ATOM5664CA PHEF66 -3.1881.744 26.873 1.00 34.31C
ATOM5665CB PHH F66 -2.6441.110 28.145 1.00 35.03C
ATOM5666CG PHEF66 -1.1501.170 28.256 1.00 38.00C
ATOM5667CDl PHEF66 -0.5361.127 29.496 1.0039.82C
ATOM5668CEl PHEF66 0.8371.190 29.591 1.00 40.00C
ATOM5669CZ PHEF66 1.6061.317 28.453 1.00 39.88C
ATOM5670CE2PHEF66 1.0181.375 27.222 1.00 38.80C
[0370]ATOM5671CD2PHEF 66 -0.352 1.298 27.121 1.00 39.84CATOM5672C PHEF 66 -4.602 1.212 26.598 1.00 32.48C
ATOM5673O PHEF 66 -5.595 1.812 26.989 1.0031.79O
ATOM5674N TYRF 67 -4.655 0.068 25.911 1.0031.23N
ATOM5675CA TYRF 67 -5.902 -0.611 25.554 1.00 30.66C
ATOM5676CB TYRF 67 -6.095 -0.612 24.031 1.00 30.93C
ATOM5677CG TYRF 67 -6.183 0.783 23.489 1.00 33.18C
ATOM5678CDl TYRF 67 -5.022 1.569 23.350 1.0031.75C
ATOM5679CEl TYRF 67 -5.081 2.855 22.900 1.00 33.71C
ATOM5680CZ TYRF 67 -6.302 3.409 22.571 1.00 33.36C
ATOM5681OH TYRF 67 -6.334 4.703 22.120 1.00 33.08O
ATOM5682CE2TYRF 67 -7.483 2.665 22.698 1.00 34.70C
ATOM5683CD2TYRF 67 -7.413 1.348 23.165 1.00 33.89C
ATOM5684C TYRF 67 -5.901 -2.054 26.049 1.00 30.13C
ATOM5685O TYRF 67 -4.835 -2.679 26.156 1.00 29.93O
ATOM5686N THRF 68 -7.112 -2.540 26.343 1.0029.28N
ATOM5687CA THRF 68 -7.424 -3.903 26.712 1.0028.64C
ATOM5688CB THRF 68 -8.203 -3.920 28.049 1.00 29.00C
ATOM5689OGl TIIRF 68 -7.286 -3.715 29.126 1.00 28.69O
ATOM5690CG2THRF 68 -8.971 -5.255 28.262 1.00 28.47C
ATOM5691C THRF 68 -8.257 -4.595 25.617 1.0027.83C
ATOM5692O THRF 68 -9.280 -4.101 25.192 1.00 27.91O
ATOM5693N LEUF 69 -7.794 -5.762 25.189 1.00 27.17N
ATOM5694CA LEUF 69 -8.493 -6.596 24.235 1.0025.85C
ATOM5695CB LEUF 69 -7.528 -7.001 23.123 1.00 25.39C
ATOM5696CG LEUF 69 -8.160 -7.682 21.912 1.00 23.42C
ATOM5697CDl LEUF 69 -8.830 -6.628 21.068 1.0019.11C
ATOM5698CD2LEUF 69 -7.079 -8.387 21.128 1.0020.62C
ATOM5699C LEUF 69 -9.025 -7.846 24.923 1.0025.54C
ATOM5700O LEUF 69 -8.298 -8.516 25.619 1.0025.59O
ATOM5701N VALF 70-10.300 -8.127 24.715 1.0025.58N
ATOM5702CA VALF 70 -10.999 -9.310 25.225 1.0025.74C
ATOM5703CB VALF 70 -12.209 -8.891 26.153 1.0025.76C
ATOM5704CGl VALF 70-12.881 -10.059 26.773 1.00 24.28C
ATOM5705CG2VALF 70-11.762 -7.929 27.249 1.00 25.73C
ATOM5706C VALF 70-11.553-10.069 24.007 1.0026.07C
ATOM5707O VALF 70-12.039 -9.465 23.086 1.00 26.02O
ATOM5708N METF 71 -11.431 -11.388 24.009 1.00 26.97N
ATOM5709CA METF 71-11.982-12.241 22.983 1.0027.41C
ATOM5710CB METF 71 -10.862-12.845 22.135 1.0027.49C
ATOM5711CG METF 71-11.332-13.888 21.159 1.0024.82C
ATOM5712SD METF 71 -10.000-14.902 20.475 1.0025.52S
ATOM5713CE METF 71 -10.973-15.785 19.231 1.00 22.37C
ATOM5714C METF 71 -12.764-13.348 23.687 1.00 28.14C
[0371]ATOM 5715O METF71-12.214-14.08924.4941.0027.91OATOM 5716N VALF72-14.057-13.40223.4141.00 27.92N·ATOM 5717CA VALF72-14.940-14.29824.1441.0028.69C
ATOM5718CB VALF72-15.847-13.54225.1801.0027.54C
ATOM 5719CGl VAL F72-15.054-13.13126.3691.0027.91C
ATOM5720CG2VALF72-16.453-12.32124.5561.00 27.52C
ATOM5721C VALF72-15.798-15.05823.1481.0029.24C
ATOM5722O VALF72-16.005-14.60022.0391.00 27.62O
ATOM5723N ASPF73-16.229-16.24423.5481.0031.05N
ATOM5724CA ASPF73-17.226-16.99622.7981.00 32.79C
ATOM5725CB ASPF73-16.749-18.41522.5051.00 32.57C
ATOM5726CG ASPF73-17.776-19.22521.7391.00 32.67C
ATOM5727ODl ASPF73-18.859-18.67821.4531.00 32.28O
ATOM5728OD2ASPF73 -17.495 -20.40221.3981.00 32.23O
ATOM5729C ASPF73-18.509-16.99323.6551.00 34.39C
ATOM5730O ASPF73-18.535-17.59924.7441.00 34.91O
ATOM5731N PROF74-19.549-16.23923.2011.00 35.23N
ATOM5732CA PROF74-20.834-16.16323.9081.0035.81C
ATOM5733CB PROF74 -21.449-14.87223.3581.00 35.97C
ATOM5734CG PROF74-20.856-14.714 21.9911.00 35.22C
ATOM5735CD PROF74-19.533-15.39921.9811.00 34.27C
ATOM5736C PRO F74 -21.755-17.37123.6171.00 36.92C
ATOM5737O PROF74 -22.814-17.51224.2451.00 37.50O
ATOM5738N ASPF75 -21.345-18.22722.6771.00 37.17N
ATOM5739CA ASPF75 -22.116-19.39722.3021.00 37.13C
ATOM5740CB ASPF75 -22.383 -19.38920.7771.00 36.48C
ATOM5741CG ASPF75 -23.034-18.07320.2941.00 36.83C
ATOM5742ODl ASPF75 -23.900-17.51821.0111.00 36.88O
ATOM5743OD2ASPF75 -22.674-17.56819.2021.00 36.70O
ATOM5744C ASPF75-21.480 -20.70922.7901.0037.25C
ATOM5745O ASPF75 -21.652 -21.75822.1751.0038.11O
ATOM5746N ALAF76 -20.783 -20.65823.9191.00 37.46N
ATOM5747CA ALAF76 -20.179-21.85124.5151.00 37.82C
ATOM5748CB ALAF76-18.841 -21.50625.1691.00 38.08C
ATOM5749C ALAF76 -21.099-22.55425.5361.00 38.06C
ATOM5750O ALAF76 -21.717-21.89326.3641.00 37.20O
AiOM5751N PROF77-21.200-23.90525.4651.00 38.54N
ATOM5752CA PROF77-20.664 -24.79924.4151.00 38.58C
ATOM5753CB PROF77 -20.644-26.16625.1011.00 38.75C
ATOM5754CG PROF77-21.741 -26.09926.1191.00 37.92C
ATOM5755CD PROF77 -21.873-24.65826.5441.00 38.21C
ATOM5756C PROF77 -21.539-24.87323.1591.00 39.37C
ATOM5757O PROF77 -21.210-25.59522.2151.00 39.42O
ATOM5758N SERF78 -22.632 -24.11623.1381.0040.02N
[0372]ATOM5759CA SERF78 -23.622 -24.23022.0661.0040.35CATOM5760 CB SERF78 -24.567 -25.40122.3521.00 40.55C
ATOM5761OG SERF78 -25.491 -25.56821.2991.00 39.58O
ATOM5762C SERF78 -24.426-22.93921.9141.00 40.82C
ATOM5763O SERF78 -24.826 -22.34322.9111.00 40.51O
ATOM5764N PROF79 -24.667 -22.49120.6651.0041.34N
ATOM5765CA PROF79-25.541 -21.336 20.5411.0041.89C ATOM5766CB PROF79 -25.487 -21.015 19.0501.0042.19C
ATOM5767CG PROF79 -25.129-22.319 18.3911.00 41.87C
ATOM5768CD PROF79 -24.197-22.975 19.3551.00 41.36C
ATOM5769C PROF79 -26.969 -21.67421.0011.00 42.59C
ATOM5770O PROF79-27.703 -20.78721.4661.00 42.89O
ATOM5771N SERF80 -27.344 -22.94820.9031.0042.94N
ATOM5772CA SERF80-28.651 -23.41621.3981.00 43.64C
ATOM5773CB SERF80-29.1]2-24.66220.6241.0043.65C
ATOM5774OG SERF80 -28.034 -25.22019.8791.00 45.08O
ATOM5775C SERF80 -28.672-23.64022.9211.0043.63C
ATOM5776O SERF80-29.729 -23.57023.5481.0043.46O
ATOM5777N ASPF81-27.495 -23.85723.5111.0043.50N
ATOM5778CA ASPF81 -27.363 -23.99324.9601.00 43.41C
ATOM5779CB ASPF81-27.461 -25.45825.3691.0043.67C
ATOM5780CG ASPF81 -27.453 -25.63126.8691.00 46.10C
ATOM5781ODI ASP F81 -27.981 -24.73527.5651.00 48.18O
ATOM5782OD2ASPF81-26.913-26.64827.3551.0048.34O
ATOM5783C ASPF81 -26.049 -23.36125.4911.0042.87C
ATOM5784O ASPF81 -25.075 -24.06825.8191.0042.85O
ATOM5785N PROF82 -26.019-22.02225.5811.00 41.48N
ATOM5786CA PROF82-24.765 -21.35625.8381.0040.48C
ATOM5787CB PROF82 -24.969 -20.00025.1671.00 39.94C
ATOM5788CG PROF82 -26.440 -19.72025.3691.0041.12C
ATOM5789CD PROF82-27.135-21.06825.4421.00 41.95C
ATOM5790C PROF82-24.495 -21.22927.3421.00 39.68C
ATOM5791O PROF82 -24.326 -20.12227.8501.00 39.16O
ATOM5792N ASNF83 -24.456 -22.36428.0361.00 38.86N
ATOM5793CA ASNF83 -24.401 -22.368 29.4971.00 38.69C
ATOM5794CB ASNF83-24.834 -23.74830.0601.00 39.01C
ATOM5795CG ASNF83 -23.852 -24.871 29.7451.0040.71C
ATOM5796ODl ASN F83 -22.751-24.93930.3091.0043.67O
ATOM5797ND2ASNF83 -24.263 -25.78628.8721.00 42.04N
ATOM5798C ASNF83 -23.069 -21.84630.0931.00 38.14C
ATOM5799O ASNF83 -22.957 -21.55631.3011.00 37.87O
ATOM5800N LEUF84-22.100 -21.66529.2041.00 36.95N
ATOM5801CA LEUF84 -20.764-21.28529.5521.00 36.43C
ATOM5802CB LEUF84-19.780 -22.18728.8131.00 36.47C
[0373]ATOM 5861 CG TRPF 90 -6.149-13.621 23.166 1.0021.28 C ATOM 5862 CDl TRPF 90 -4.980-13.79私 23.848 1.0021.66 C ATOM 5863 NEl TRPF 90 -3.939-13.215 23.158 1.0021.90 M ATOM 586私 CE2TRPF 90 -4.435-12.636 22013 100 22.37 n ATOM 5865 CD2TRPF 90 -5.823-12.877 21.985 10021.90 O ATOM 5866 CE3TRPF 90 -6.581 -12.416 20.879 10021.18 O ATOM 5867 CZ3TRPF 90 -5_941 -11.726 19.871 1.00 23.15 C ATOM 5868 CH2TRPF 90 -4.541 -11.451 19.941 1.0023.40 O ATOM 5869 CZ2TRPF 90 -3.776-11.908 21.004 1.00 24.19 O ATOM 5870 C TRPF 90 -8.158-13.136 25.756 100 21.89 n ATOM 5871 OHJ^PP -9.264-12.660 25.720 1.00 20.45 O ATOM 5872¾LEUF 91 -7.153-12.6s 26.455 一0022.96 N ATOM 5873 CA LEUF 91 -7.251-11.319 27072 £02319 n ATOM 5874 S LEUF 91 -70082-11.463 28.479 1.0024.32 O ATOM 5875 Oo LEUF 91 -8.011 -10.283 29.462 1.0024.17 O ATOM 5876 CDl LEU F 91 -8·687 -9.160 28.840 1.0025.45 C ATOM 5877 CD2LEUF 91 -8.799-10.674 30.692 100 25.30 O ATOM 58700O 尸msS—50062-10.6800^.0 100 24.45 C ATOM 5879 OrWUF 91 27.646 1.0022.51 O ATOM 5880 N VALF 92 -5.761 -9.486 26.570 100 26.26 N ATOM 5881 CA VALF 92 -4.518 -8.728 26.423 1.00 27.66 n Α1ΌΜ 5882 πω VALF 92 -3.967 -8.712 24.954 1.0027.10 C ATOM 5883 CGl VALF S -2.572 -8.160 24.936 1.0028.34 O ATOM 5884 CG2VALF 92 -3.959-10087 24.358 1.00 26.57 C ATOM 5885 C VALF 92 -4.797 -7.303 26.935 100 28.47 O ATOM 5886 O VALF 92 -5.795 -6.686 26.552 1.0028.68 O ATOM 5887 N THRF 93 -3.935 -6.842 27.843 100 29.24¾ ATOM 5888 CA THRF 93 -40 04 ,5.518 28.475 100 29.87 n ATOM 5889 οωHJ丨^ isU1200wps一 100 29.81 O ATOM 5890 OGl THRF 93 -2.917 ,6.236 30.523 100 30.11 〇
S37S
159ATOM5891CG2THRF 93 -5.303 -6.481 30.460 1.00 30.90C
ATOM5892C THRF 93 -2.712 -4.771 28.190 1.00 29.77C
ATOM5893O THRF 93 -1.778 -5.341 27.657 1.00 29.35O
ATOM5894N ASPF 94 -2.679 -3.494 28.565 1.00 30.32N
ATOM5895CA ASPF 94 -1.518 -2.611 28.379 1.00 30.81C
ATOM5896CB ASPF 94 -0.401 -2.953 29.369 1.00 30.45C
ATOM5897CG ASPF 94 -0.729 -2.525 30.780 1.0031.98C
ATOM5898ODl ASPF 94 -1.778 -1.906 30.985 1.00 33.26O
ATOM5899OD2ASPF 94 0.072 -2.804 31.697 1.00 34.82O
ATOM5900C ASPF 94 -0.982 -2.561 26.955 1.00 30.43C
ATOM5901O ASPF 94 0.239 -2.531 26.740 1.00 30.45O
ATOM5902N ILEF 95 -1.897 -2.567 25.992 1.00 30.02N
ATOM5903CA ILEF 95 -1.517 -2.500 24.603 1.0029.16C
ATOM5904CB ILEF 95 -2.607 -3.069 23.621 1.0029.16C
ΑΓΟΜ5905CGl ILEF 95 -2.999 -4.511 23.956 1.00 27.34C
ATOM5906CDl ILEF 95 -4.210 -5.036 23.173 1.00 27.16C
ATOM5907CG2ILEF 95 -2.083 -2.966 22.178 1.00 27.80C
ATOM5908C ILEF 95 -1.340 -1.029 24.306 1.00 29.95C
ATOM5909O ILEF 95 -2.304 -0.257 24.401 1.0029.12O
ATOM5910N PROF 96 -0.113 -0.619 23.949 1.00 30.73N
ATOM5911CA PROF 96 0.030 0.811 23.663 1.00 30.67C
ATOM5912CB PROF 96 1.554 1.011 23.578 1.00 30.47C
ATOM5913CG PROF 96 2.149 -0.251 24.145 1.0030.49C
ATOM5914CD PROF 96 1.173 -1.335 23.836 1.00 30.19C
ATOM5915C PROF 96 -0.658 1.240 22.365 1.00 30.88C
ATOM5916O PROF 96 -0.604 0.524 21.357 1.00 30.51O
ATOM5917N GLYF 97 -1.313 2.399 22.417 1.0031.54N
ATOM5918CA GLYF 97 -1.920 3.004 21.238 1.00 32.12C
ATOM5919C GLYF 97 -0.961 3.098 20.059 1.0031.90C
ATOM5920O GLYF 97 0.222 3.398 20.253 1.00 30.70O
ATOM5921N THRF 98 -1.509 2.868 18.850 1.0031.66N
ATOM5922CA THRF 98 -0.791 2.787 17.539 1.00 31.84C
ATOM5923CB THRF 98 0.085 4.026 17.159 1.00 32.77C
ATOM5924OGl THRF 98 1.327 3.993 17.893 1.00 33.65O
ATOM5925CG2THRF 98 -0.683 5.375 17.350 1.00 30.86C
ATOM5926C THRF 98 0.024 1.522 17.290 1.0031.79C
ATOM5927O THRF 98 0.698 1.398 16.258 1.00 32.41O
ATOM5928N THRF 99 -0.043 0.572 18.212 1.0031.18N
ATOM5929CA THRF 99 0.679 -0.661 18.049 1.00 30.07C
ATOM5930CB THRF 99 1.644 -0.961 19.253 1.00 30.42C
ATOM5931OGl THRF 99 0.898 -1.358 20.420 1.00 29.57O
ATOM5932CG2THRF 99 2.580 0.252 19.575 1.00 28.92C
ATOM5933C THRF 99 -0.317 -1.800 17.800 1.00 29.85C
ATOM5934O THRF 99 -1.139 -1.732 16.885 1.00 30.29O
[0376]ATOM5979CD GLUF 106 -0.502 -14.94425.9951.00 38.79 C
ATOM5980OEl GLU F 106 -0.418-14.64924.7821.00 39.50O
ATOM5981OE2GLUF 106 0.020-15.97026.5011.0040.01O ATOM5982C GLUF 106 -1.604-11.97229.1581.0031.05C
ATOM5983O GLUF 106 -0.837-12.50029.9431.0031.56O
ATOM5984N VALF 107 -2.865-11.67829.4581.00 30.36N
ATOM5985CA VALF 107 -3.488-11.98930.7421.0028.43C
ATOM5986CB VALF 107 -4.504-10.88431.1251.0028.50C
ATOM5987CGl VAL F 107 -5.561 -11.43032.0261.0029.49C
ATOM5988CG2VALF 107 -3.790 -9.68931.8201.00 30.15C
ΑΓΟΜ5989C VALF107 -4.142-13.38230.7521.00 27.21C
ATOM5990O VALF 107 -3.944-14.13531.6851.00 25.00O
ATOM5991N METF 108 -4.981 -13.67029.7421.0025.94N
ATOM5992CA METF 108 -5.430-15.00929.450 1.0024.74 C
ATOM5993CB METF 108 -6.968-15.05329.3261.00 24.57 C
ATOM5994CG METF 108 -7.534-16.46329.1531.0025.01 C
ATOM5995SD METF 108 -7.322-17.58130.5711.0029.21 S
ATOM5996CE METF 108 -8.560-16.95031.7041.00 24.20 C
ATOM5997C METF 108 -4.772-15.46628.1401.0024.64C
ATOM5998O METF 108 -4.934 -14.82227.0731.0024.88O
ATOM5999N SERF 109 -4.044-16.57428.1821.00 24.83N
ATOM6000CA SERF 109 -3.395 -17.02326.9531.0025.74C
ATOM6001CB SERF 109 -2.365-18.10727.2131.00 25.49C
ATOM6002OG SERF 109 -2.930-19.34527.6021.0027.22O
ATOM6003C SERF 109 -4.441 -17.44925.8981.00 26.47C
ATOM6004O SERF 109 -5.543 -17.89126.2551.00 25.79O
ATOM6005N TYRF HO -4.108 -17.24324.6201.00 25.92N
ATOM6006CA TYRF 110 -4.975 -17.60923.4911.0025.16C
ATOM6007CB TYRF HO -4.370-17.11222.1661.0025.23C
ATOM6008CG TYRF 110 -5.286-17.28320.9571.0024.81C
ATOM6009CDl TYRF110 -5.235-18.42320.1651.0023.91C
ATOM6010CEl TYRF HO -6.082-18.54919.0781.00 25.85C
ATOM6011CZ TYRF 110 -6.951 -17.51518.7761.00 23.55C
ATOM6012Oil TYRF HO -7.792-17.59717.7341.00 24.52 O
ATOM6013CE2 TYRF110 -6.997-16.39219.5311.0022.01C
ATOM6014CD2TYRF 110 -6.185-16.29320.6151.0025.42C
ATOM6015C TYRF110 -5.245-19.10123.3891.00 25.50C
ATOM6016O TYRF HO -4.325 -19.91723.2421.00 24.43O
ATOM6017N GLUF 111 -6.534-19.44623.4341.0026.16N
ATOM6018CA GLUF 111 -7.001 -20.81223.1291.0025.09C
ATOM6019CB GLUF 111 -7.899-21.32824.2591.0024.78C
ATOM6020CO GLUF 111 -8.079-22.81224.3021.0022.72C
ATOM6021CD GLUF 111 -8.997-23.25225.4291.0025.80C
ATOM6022OEl GLUF 111 -8.468 -23.63826.4881.00 24.44O[0378]ATOM6023OE2 GLUF 111 -10.253 -23.260 25.2571.0029.25O
ATOM6024C GLUF 111 -7.756-20.876 21.8001.0025.21C
ATOM6025O GLUF 111 -8.635 -20.085 21.555 1.0025.04O
ATOM6026N SERF 112 -7.386 -21.834 20.9581.00 25.79N
ATOM6027CA SERF 112 -7.955 -22.039 19.635 1.0027.24C
ATOM6028CB SERF 112 -7.237-23.215 18.934 1.0027.08C
ATOM6029OG SERF 112 -5.818-23.116 19.043 1.0028.72O ATOM6030C SERF 112 -9.478 -22.328 19.6871.00 27.94C
ATOM6031O SERF 112 -9.898 -23.312 20.2861.00 26.83O
ATOM6032N PRO F 113-10.294 -21.455 19.0641.00 29.50N
ATOM6033CA PRO F 113-11.731 -21.800 18.8781.0031.22C
ATOM6034CB PRO F 113-12.191 -20.776 17.8241.00 30.05C
ATOM6035CG PRO F 113-11.311 -19.521 18.1491.00 29.17C
ATOM6036CD PROF 113 -9.957-20.128 18.481 1.0029.49C
ATOM6037C PRO F 113-11.898 -23.251 18.3911.00 32.64C
ATOM6038O PRO F 113-11.256 -23.624 17.4111.00 32.85O
ATOM6039N ARGF 114-12.687-24.070 19.1051.00 35.07N
ATOM6040CA ARGF 114-13.111-25.413 18.6041.00 37.65C
ATOM6041CB ARGF114-12.351 -26.580 19.2621.00 37.84C
ATOM6042CG ARGF 114-10.792-26.479 19.310 1.00 39.73C
ATOM6043CD ARGF 114-10.082 -27.118 18.096 1.0042.97C
ATOM6044NE ARGF 114-10.279-28.567 18.0921.0045.74N
ATOM6045CZ ARGF 114 -9.467 -29.458 18.668 1.0047.62 C
ATOM6046NHl ARG F 114 -8.339 -29.090 19.285 1.0048.92N
ATOM6047NH2ARGF 114 -9.787-30.739 18.628 1.0048.66N
ATOM6048C ARGF 114-14.646-25.609 18.7641.00 39.46C
ATOM6049O ARGF 114-15.101 -26.340 19.6601.00 39.45O
ATOM6050N PRO F 115-15.444-24.940 17.9001.00 40.53N
ATOM6051CA PRO F 115-16.907 -24.999 17.9081.00 41.65C
ATOM6052CB PROF 115-17.288-23.874 16.9621.00 40.86C
ATOM6053CG PROF 115-16.154-23.813 16.0081.0040.43C
ATOM6054CD PRO F 115-14.953 -24.032 16.8451.00 40.41C
ATOM6055C PROF 115-17.456-26.305 17.3551.0043.09C
ATOM6056O PRO F 115-16.723 -27.042 16.7011.00 43.07O
ATOM6057N THRF 116-18.731 -26.583 17.6261.0045.33N
ATOM6058CA THRF 116-19.491 -27.609 16.8621.00 47.86C
ATOM6059CB THRF 116-20.407 -28.466 17.7881.00 48.32C
ATOM6060OGl THRF116 -20.052 -28.248 19.1651.00 49.13O
ATOM6061CG2 THR F 116 -20.197 -29.960 17.4901.0048.44C
ATOM6062C THRF 116-20.089 -26.987 15.5251.00 48.62C
ATOM6063O THRF 116-19.589 -25.938 15.1281.0048.43O
ATOM6064N METF 117-21.137-27.488 14.8341.0050.12N
ATOM6065CA METF 117-22.461-27.959 15.312 1.0051.27C
ATOM6066CB METF 117-22.509 -29.433 15.6841.00 51.58C
[0379]ATOM6067CG MET F 117 -22.294 -30.266 14.484 1.0051.87CATOM6068SD METF 117-21.565 -31.827 14.964 1.00 54.77S
ATOM6069CE METF 117-21.492-32.626 13.316 1.00 54.08C
ATOM6070C METF 117-23.177-26.960 16.251 1.00 50.24C
ATOM6071O METF 117-23.308 -27.109 17.497 1.00 50.77O
ATOM6072N GLYF 118-23.654 -25.943 15.543 1.00 48.86N
ATOM6073CA GLYF118-23.928 -24.636 16.056 1.0047.26C
ATOM6074C GLYF 118-22.755-23.801 15.598 1.00 46.06C
ATOM6075O GLYF 118-21.614-24.100 15.945 1.00 45.99O
ATOM6076N ILEF 119-23.035-22.799 14.770 1.00 44.92N
ATOM6077CA ILEF 119-22.093 -21.714 14.475 1.00 43.41C
ATOM6078CB ILE F 119 -22.645 -20.795 13.364 1.00 42.95C
ATOM6079CGl ILEF 119-22.617-21.483 12.010 1.0044.68C
ATOM6080CDl ILEF 119-23.996-21.822 11.459 1.0045.15C
ATOM6081CG2ILEF 119-21.884-19.496 13.305 1.00 43.80C
ATOM6082C ILEF 119-21.889-20.868 15.747 1.0041.96C
ATOM6083O ILEF 119-22.876-20.406 16.339 1.00 42.32O
ATOM6084N HIS F120 -20.629 -20.676 16.167 1.00 39.68N
ATOM6085CA HIS F 120-20.313-19.832 17.325 1.00 37.19C
ATOM6086CB HIS F 120-19.225 -20.456 18.212 1.00 37.42C
ATOM6087CG HIS F 120-19.597-21.781 18.808 1.00 36.72C
ATOM6088NDl HIS F 120 -19.052 -22.240 19.991 1.00 34.31N
ATOM6089CEl HIS F 120-19.549 -23.435 20.260 1.00 36.45C
ATOM6090NE2 HIS F120 -20.401 -23.764 19.299 1.00 35.07N
ATOM6091CD2 HIS F 120 -20.443 -22.749 18.378 1.00 34.29C
ATOM6092C HlSF 120-19.786-18.509 16.821 1.00 35.77C
ATOM6093O HISF 120-19.061-18.485 15.824 1.00 35.44O
ATOM6094N ARGF 121 -20.160-17.422 17.495 1.00 33.59N
ATOM6095CA ARGF121 -19.561 -16.122 17.248 1.00 32.62C
ATOM6096CB ARGF121 -20.520-14.996 17.671 1.00 33.00C
ATOM6097CG ARGF 121 -21.863-14.940 16.944 1.00 30.84C
ATOM6098CD ARGF 121 -22.818-13.999 17.657 1.00 31.32C
ATOM6099NE ARG F 121-23.407-14.639 18.830 1.00 32.25N
ATOM6100CZ ARGF 121-24.049-13.993 19.803 1.00 33.38C
ATOM6101NHl ARGF 121 -24.178 -12.677 19.757 1.00 33.13N
ATOM6102NH2 ARGF 121 -24.558 -14.666 20.838 1.00 34.55N
ATOM6103C ARGF 121 -18.293-16.046 18.101 1.00 32.34C
ATOM6104O ARGF 121 -18.288-16.537 19.227 1.00 32.73O
ATOM6105N LEUF 122-17.226-15.442 17.591 1.0031.98N
ATOM6106CA LEUF122-16.020-15.187 18.423 1.0031.14C
ATOM6107CB LEUF 122-14.782-15.932 17.916 1.00 30.82C
ATOM6108CG LEU F122-14.609-17.440 18.122 1.0029.67C
ATOM6109CDl LEU F 122-14.578 -17.867 19.598 1.0028.49C
ATOM6110CD2LEUF 122-15.682-18.212 17.354 1.0031.85C
[0380]L[ΐ8εο]
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O617-1E 00'I Lei'Ll 0£ΓΠ-江I ίί!3Ί OΖ119WOIVATOM6155C PHEF 127-10.248-0.125 25.788 1.0033.43C
ATOM6156O PHEF127-9.171-0.608 25.506 1.00 33.23O
ATOM6157N GLNF 128-10.3841.130 26.172 1.00 36.14N
ATOM6158CA GLNF 128-9.2041.908 26.505 1.00 38.86C
ATOM6159CB GLNF 128-9.0993.200 25.675 1.00 39.08C
ATOM6160CG GLNF 128-9.8264.437 26.152 1.00 40.54C
ATOM6161CD GLNF 128-9.1415.722 25.658 1.00 40.85C
ATOM6162OEl GLNF128-9.2776.105 24.477 1.0040.98O
ATOM6163NE2 GLNF128-8.3826.376 26.558 1.00 39.20N
ATOM6164C GLNF 128-9.1472.133 28.000 1.00 39.70C
ATOM6165O GLNF128-10.1352.494 28.625 1.00 39.97O
ATOM6166N GLNF 129-7.9871.857 28.578 1.0041.79N
ATOM6167CA GLNF 129-7.8221.933 30.021 1.00 42.80C
ATOM6168CB GLN F 129-6.5861.129 30.451 1.00 42.68C
ATOM6169CG GLNF 129-6.662-0.346 30.081 1.0040.47C
ATOM6170CD GLNF 129-5.325-1.052 29.967 1.00 37.72C
ATOM6171OEl GLNF129-5.215-2.054 29.257 1.00 36.71O
ATOM6172NE2 GLNF129-4.314-0.556 30.669 1.00 35.01N
ATOM6173C GLNF129-7.6673.384 30.391 1.0044.60C
ATOM6174O GLNF 129-7.2594.187 29.570 1.0044.44O
ATOM6175N LEUF130-7.9903.735 31.625 1.00 47.50N
ATOM6176CA LEUF 130-7.6705.079 32.101 1.00 50.33C
ATOM6177CB LEUF130-8.4015.394 33.412 1.00 50.53C
ATOM6178CG LEUF 130-9.8975.794 33.384 1.0051.61C
ATOM6179CDl LEUF 130-10.6895.470 32.065 1.00 53.31C
ATOM6180CD2 LEU F130-10.5985.173 34.598 1.00 53.16C
ATOM6181C LEUF 130-6.1385.254 32.216 1.00 51.95C
ATOM6182O LEUF130-5.6286.382 32.169 1.00 52.36O
ATOM6183N GLYF131-5.4274.125 32.336 1.0053.80N
ATOM6184CA GLYF 131-3.9594.055 32.297 1.00 55.35C
ATOM6185C GLYF 131-3.4422.716 32.801 1.00 56.70C
ATOM6186O GLYF 131-4.2341.832 33.134 1.00 56.76O
ATOM6187N ARGF132-2.1112.573 32.852 1.00 57.98N
ATOM6188CA ARGF 132-1.4291.429 33.492 1.00 58.92C
ATOM6189CB ARGF 1320.0221.780 33.817 1.0059.11C
ATOM6190CG ARGF 1320.9911.333 32.791 1.00 60.24C
ATOM6191CD ARGF 1322.4261.275 33.325 1.00 63.55C
ATOM6192NE ARGF 1323.1830.292 32.552 1.00 64.86N
ATOM6193CZ ARGF 1323.7400.530 31.366 1.00 65.22C ATOM6194NHl ARG F1323.6591.746 30.835 1.00 65.91N
ATOM6195NH2ARGF1324.394-0.439 30.719 1.00 63.10N
ATOM6196C ARGF132-2.0980.971 34.780 1.00 59.31C
ATOM6197O ARGF132-2.0761.673 35.788 1.00 59.66O
ATOM6198N GLNF 133-2.670-0.224 34.740 1.00 59.64N
[0382]ATOM 6199CA GLNF 133 -3.426 -0.761 35.861 1.00 59.76 CATOM 6200CB GLNF133 -4.897 -0.387 35.719 1.00 59.67 C
ATOM 6201CG GLNF 133 -5.461 -0.627 34.317 1.00 59.90 C
ATOM 6202CD GLNF 133 -6.954 -0.805 34.326 1.00 60.46 C
ATOM6203OEl GLNF 133 -7.507 -1.415 35.245 1.00 60.96 O
ATOM 6204NE2 GLNF 133 -7.624 -0.281 33.305 1.00 59.84N
ATOM6205C GLNF 133 -3.272 -2.284 35.937 1.00 59.82C ATOM6206O GLNF 133 -3.233 -2.973 34.903 1.00 60.24 O
ATOM6207N THRF 134 -3.176 -2.800 37.159 1.00 59.32N
ATOM6208CA THRF 134 -3.035 -4.232 37.358 1.00 58.98 C
ATOM6209CB THRF134 -2.513 -4.566 38.777 1.00 59.05 C
ATOM6210OGl THRF 134 -1.417 -3.693 39.103 1.00 59.25O
ATOM6211CG2THRF 134 -2.046 -6.014 38.859 1.00 58.43C
ATOM6212C THRF134 -4.382 -4.897 37.063 1.00 58.56C
ATOM6213O THRF 134 -5.382 -4.642 37.729 1.00 58.47O
ATOM6214N VALF 135 -4.391 -5.719 36.024 1.00 58.38N
ATOM6215CA VALF 135 -5.578 -6.450 35.583 1.00 57.70 C
ATOM6216CB VALF 135 -5.842 -6.198 34.091 1.00 57.76C
ATOM6217CGl VALF 135 -7.094 -6.938 33.624 1.00 57.99C
ATOM6218CG2VALF 135 -5.930 -4.690 33.794 1.00 57.44C
ATOM6219C VALF 135 -5.285 -7.924 35.802 1.00 57.42C
ATOM6220O VALF 135 -4.287 -8.434 35.302 1.00 58.03O
ATOM6221N TYRF 136 -6.117 -8.606 36.576 1.00 56.88N
ATOM6222CA TYRF 136 -5.904-10.024 36.822 1.00 56.34C
ATOM6223CB TYRF 136 -6.150-10.381 38.287 1.00 57.22C
ATOM6224CG TYRF 136 -5.098 -9.812 39.204 1.00 58.77 C
ATOM6225CDlTYR F 136 -5.443 -8.930 40.238 1.00 60.37C
ATOM6226CEl TYRF 136 -4.463 -8.386 41.087 1.00 59.83C
ATOM6227CZ TYRF 136 -3.126 -8.724 40.895 1.00 60.04C
ATOM6228OH TYRF 136 -2.150 -8.197 41.720 1.00 59.45 O
ATOM6229CE2TYRF 136 -2.759 -9.598 39.867 1.00 60.26C
ATOM6230CD2TYRF 136 -3.744-10.133 39.027 1.00 59.45C
ATOM6231C TYRF 136 -6.743 -10.884 35.877 1.00 55.66C
ATOM6232O TYRF 136 -7.662-10.388 35.224 1.00 55.49O
ATOM6233N ALAF 137 -6.381 -12.161 35.772 1.00 54.46N
ATOM6234CA ALAF 137 -7.088 -13.096 34.916 1.00 52.90C
ATOM6235CB ALAF 137 -6.123-14.132 34.339 1.00 53.03C
ATOM6236C ALAF 137 -8.162-13.782 35.740 1.00 51.71C
ATOM6237O ALAF 137 -7.912-14.140 36.903 1.0051.57O
ATOM6238N PROF 138 -9.364-13.974 35.150 1.00 50.31N
ATOM6239CA PROF 138-10.301 -14.829 35.863 1.0048.91C
ATOM6240CB PRO F 138-11.472-14.963 34.887 1.00 48.68C
ATOM6241CG PRO F 138-11.359-13.814 33.993 1.00 49.49C
ATOM6242CD PROF 138 -9.918-13.482 33.872 1.00 50.09C
[0383]ATOM6243C PROF 138 -9.611 -16.165 36.081 1.0047.90 CATOM6244O PRO F138 -8.707-16.517 35.315 1.0048.52 O
ATOM6245N GLYF 139 -9.992-16.895 37.122 1.0046.73 N
ATOM6246CA GLYF 139 -9.345-18.174 37.418 1.00 44.60 C
ATOM6247C GLYF 139 -9.836-19.314 36.540 1.00 43.64 C
ATOM6248O GLYF 139 -9.350 -20.467 36.662 1.00 43.60 O
ATOM6249N TRPF140-10.819-19.005 35.685 1.0041.62N
ATOM6250CA TRPF 140-11.381 -19.952 34.714 1.00 40.19C ATOM6251CB TRPF 140-12.553 -20.743 35.304 1.00 40.67C
ATOM6252CG TRPF 140-13.473-19.865 36.023 1.0040.65C
ATOM6253CDl TRPF140 -14.477 -19.134 35.490 1.00 41.85C
ATOM6254NEl TRPF 140-15.080-18.381 36.465 1.00 43.61N
ATOM6255CE2 TRPF 140-14.446-18.606 37.662 1.0042.94C
ATOM6256CD2 TRPF140 -13.419 -19.535 37.419 1.00 42.05C
ATOM6257CE3 TRPF 140-12.607-19.954 38.491 1.0042.43C
ATOM6258CZ3 TRPF 140-12.853 -19.438 39.764 1.0042.58C
ATOM6259CH2 TRPF140-13.897-18.511 39.978 1.0042.82C
ATOM6260CZ2TRPF 140-14.700-18.080 38.940 1.00 43.54C
ATOM6261C TRPF 140-11.849-19.189 33.489 1.00 39.28C
ATOM6262O TRPF 140-12.075-17.979 33.536 1.00 39.41O
ATOM6263N ARGF 141-12.020-19.913 32.394 1.00 37.72N
ATOM6264CA ARGF 141 -12.421 -19.308 31.129 1.0035.64 C
ATOM6265CB ARGF141 -11.849 -20.121 29.992 1.00 35.76 C
ATOM6266CG ARGF 141 -10.376-19.931 29.911 1.00 33.45 C
ATOM6267CD ARGF 141 -9.734 -20.815 28.919 1.00 32.87 C
ATOM6268NE ARGF 141 -9.046-19.938 28.014 1.00 37.46 N
ATOM6269CZ ARG F 141 -7.802 -20.043 27.608 1.00 32.84 C
ATOM6270NHl ARGF 141 -7.041 -21.037 27.976 1.00 37.52 N
ATOM6271NH2ARGF141 -7.362-19.152 26.773 1.0032.60 N
ATOM6272C ARGF 141 -13.918-19.154 30.961 1.00 34.68C
ATOM6273O ARG F 141 -14.375-18.124 30.470 1.00 34.54O
ATOM6274N GLNF 142-14.666-20.162 31.393 1.00 33.45N
ATOM6275CA GLNF 142-16.137 -20.174 31.324 1.00 33.02 C
ATOM6276CB GLNF 142-16.670-21.571 31.657 1.00 33.49 C
ATOM6277CG GLNF 142-16.680 -21.883 33.134 1.00 34.07 C
ATOM6278CD GLNF 142-15.422 -22.582 33.636 1.00 38.13 C
ATOM6279OEl GLNF 142 -14.291 -22.315 33.189 1.00 40.14O
ATOM6280NE2 GLN F 142 -15.612 -23.467 34.600 1.00 36.44N
ATOM6281C GLNF 142-16.821 -19.138 32.227 1.00 32.60C
ATOM6282O GLNF 142-16.241 -18.680 33.230 1.0031.72O
ATOM6283N ASNF143-18.041 -18.752 31.837 1.0031.79N
ATOM6284CA ASNF143-18.892-17.825 32.617 1.00 32.38 C
ATOM6285CB ASNF 143-19.480-18.531 33.865 1.0032.13 C
ATOM6286CG ASNF 143 -20.409-19.685 33.471 1.00 33.60 C
[0384]ATOM6287ODl ASN F 143 -21.397-19.47732.7471.00 35.01OATOM6288ND2 ASN F 143 -20.066 -20.89833.8801.0031.86N
ATOM6289C ASNF143-18.246-16.47132.9331.00 32.38C
ATOM6290O ASNF143-18.498-15.87433.9811.00 32.28O
ATOM6291N PHEF144-17.411 -16.01631.9891.00 32.16N
ATOM6292CA PHEF 144-16.841 -14.68031.9701.0031.01C
ATOM6293CB PHEF 144-15.699-14.62130.9321.00 29.94C
ATOM6294CG PHEF 144-14.946-13.32630.9111.00 26.86C
ATOM6295CDl PHEF 144-15.115-12.42329.8711.0024.09C
ATOM6296CEl PHEF 144-14.394-11.20529.8481.0022.51C
ATOM6297CZ PHEF144-13.491 -10.91830.8651.00 23.77C
ATOM6298CE2 PHE F 144-13.314-11.81231.9161.0021.52C
ATOM6299CD2 PHEF 144-14.029-13.00831.9401.0027.58C
ATOM6300C PHEF 144-17.932-13.67031.6321.0031.28C
ATOM6301O PHEF 144-18.861-13.96130.8641.00 31.51O
ATOM6302N ASNF145-17.821 -12.49132.2261.0031.49N
ΑΓΟΜ6303CA ASNF 145-18.682-11.37631.8811.00 32.01C
ATOM6304CB ASN F 145-19.583-11.04033.0621.0031.88C
ATOM6305CG ASNF 145 -20.749-10.24932.6491.0031.50C
ATOM6306ODl ASNF 145 -20.688 -9.03132.6511.00 30.49O
ATOM6307ND2 ASNF 145 -21.834 -10.93332.2361.00 28.85N
ATOM6308C ASNF 145-17.890-10.13431.4611.0031.81C
ATOM6309O ASN F 145-17.229 -9.52432.2831.00 32.21O
ATOM6310N THRF 146-17.944 -9.77130.1821.00 32.02N
ATOM6311CA THRF 146-17.200 -8.606 29.704 1.00 32.49C
ATOM6312CB THRF 146-17.213 -8.510 28.158 1.00 32.60C
ATOM6313OGl TI IRF 146-16.632 -9.69927.6131.0031.57O
ATOM6314CG2 THRF 146-16.401 -7.32227.6751.0031.68C
ATOM6315C THRF146-17.639 -7.30430.3741.00 33.35C
ATOM6316O THRF 146-16.783 -6.49030.7931.00 33.18O
ATOM6317N LYS F 147-18.953 -7.11830.5191.00 33.83N
ATOM6318CA LYSF147-19.496 -5.94231.2341.00 35.63C
ATOM6319CB LYSF 147 -21.024 -5.84331.1141.0036.00C
ATOM6320CG LYSF147 -21.722 -7.19731.0121.00 38.49C
ATOM6321CD LYS F147 -23.264 -7.07731.0471.00 37.69C
ATOM6322CE LYS F147 -23.881 -8.45231.0211.00 37.85C
ATOM6323NZ LYSF 147 -23.577 -9.08329.7241.00 35.31N
ATOM6324C LYSF 147-19.033 -5.78032.6901.00 35.55C
ATOM6325O LYS F147-18.568 -4.70533.0591.00 36.25O
ATOM6326N ASPF 148-19.135 -6.83933.4991.0036.06N
ATOM6327CA ASPF 148-18.576 -6.86134.8551.00 36.37C
ATOM6328CB ASPF 148-18.840 -8.21235.5001.00 36.85C
ATOM6329CG ASPF148 -20.303 -8.46335.7551.00 38.15C
ATOM6330ODl ASP F148 -21.074 -7.48135.8211.00 39.47O
[0385]ATOM6375CE2 TYRF 153-10.228-7.108 36.3781.0031.08C
ATOM6376CD2 TYR F153-10,630-6.031 35.6111.00 32.50C
ATOM6377C TYRF 153-11.341-1.186 35.3191.00 39.45C
ATOM6378O TYRF 153-10.325-0.681 34.8461.0040.09O
ATOM6379N ASN F 154-12.493-0.521 35.4691.0040.52N
ATOM6380CA ASNF 154-12.6850.871 35.0211.0041.48 C
ATOM6381CB ASNF154-11.9821.858 35.9781.0042.49C
ATOM6382CG ASNF 154-12.4191.681 37.4301.00 45.86 C
ATOM6383ODl ASNF 154-13.5501.257 37.7131.0049.54O
ATOM6384ND2ASN F 154-11.5242.011 38.3581.00 45.43N
ATOM6385C ASNF 154-12.2561.106 33.5601.0040.43C
ATOM6386O ASNF 154-11.3881.932 33.2661.00 39.44O
ATOM6387N LEUF 155-12.8850.360 32.6571.00 40.12N
ATOM6388CA LEUF155-12.4910.365 31.2481.00 39.31 C
ATOM6389CB LEUF155-12.353-1.066 30.7091.00 39.17C
ATOM6390CG LEUF155-11.316-2.014 31.3101.00 37.01C
ATOM6391CDl LEU F 155 -9.890-1.446 31.2561.00 35.34C
ATOM6392CD2 LEU F 155-11.421-3.278 30.5491.00 34.92C
ATOM6393C LEUF 155-13.5261.121 30.4581.00 39.20C
ATOM6394O LEUF 155-13.3881.334 29.2481.00 38.66O
ATOM6395N GLYF 156-14.5651.527 31.1811.00 38.74N
ATOM6396CA GLYF 156-15.6892.237 30.6121.00 38.47C
ATOM6397C GLYF 156-16.4711.337 29.6861.00 37.94C
ATOM6398O GLYF 156-16.7550.183 30.0101.00 37.92O
ATOM6399N SERF 157-16.8321.903 28.5371.00 37.45N
ATOM6400CA SERF 157-17.4691.176 27.4551.00 36.78C
ATOM6401CB SERF 157-18.5262.062 26.7931.00 36.58C
ATOM6402OG SERF 157-19.0183.004 27.6981.00 37.82O
ATOM6403C SERF 157-16.3760.848 26.4241.00 35.81C
ATOM6404O SERF 157-15.2371.401 26.4911.0035.73O
ATOM6405N PRO F 158-16.711-0.022 25.4611.00 34.14N
ATOM6406CA PROF 158-15.742-0.320 24.4251.0033.79C
ATOM6407CB PROF 158-16.396-1.480 23.6311.00 33.76C
ATOM6408CG PRO F158-17.609-1.884 24.3941.00 33.15C
ATOM6409CD PRO F 158-17.989-0.738 25.2591.00 34.18C
ATOM6410C PROF 158-15.4920.893 23.5101.00 33.50C
ATOM6411O PROF 158-16.2751.863 23.4741.00 34.10O
ATOM6412N VALF 159-14.3890.834 22.7821.00 32.57N
ATOM6413CA VALF159-14.0741.850 21.8151.00 31.59C
ATOM6414CB VALF 159-12.7202.514 22.1141.00 30.62C
ATOM6415CGl VALF 159-12.7393.181 23.4671.00 29.10C
ATOM6416CG2VALF 159-11.6351.499 22.0781.00 31.32C
ATOM6417C VALF159-14.1011.208 20.4331.0031.29C
ATOM6418O VALF 159-14.1231.892 19.4161.0031.64O
[0387]ATOM6419N ALAF160-14.100 -0.12020.418 1.0031.50NATOM6420CA ALAF 160-14.155 -0.905 19.208 1.00 30.65C
ΑΓΟΜ6421CB ALAF 160-12.787 -0.965 18.532 1.00 30.27C
ATOM6422C ALAF160-14.618 -2.31119.551 1.0031.32C
ATOM6423O ALAF 160-14.433 -2.78620.689 1.0030.64O
ATOM6424N ALAF 161 -15.209 -2.97318.546 1.00 30.77N
ATOM6425CA ALAF161 -15.602 -4.378 18.647 1.00 30.82C
ATOM6426CB ALAF161 -16.793 -4.534 19.601 1.00 29.58C
ATOM6427C ALAF 161 -15.864 -4.97517.230 1.00 30.48C
ATOM6428O ALAF 161 -16.209 -4.24316.314 1.0029.83O
ATOM6429N VALF 162-15.611 -6.28217.074 1.00 31.51N
ATOM6430CA VALF 162-15.774 -7.077 15.825 1.0031.03C
ATOM6431CB VALF 162-14.591 -6.825 14.778 1.0031.49C
ATOM6432CGl VALF 162-13.273 -7.49215.192 1.00 30.07C
ATOM6433CG2 VALF 162-14.971 -7.22513.379 1.0030.18C
ATOM6434C VALF 162-15.894 -8.58416.178 1.0031.89C
ATOM6435O VALF 162-15.340 -9.04217.184 1.0031.52O
ATOM6436N TYRF 163-16.625 -9.34515.361 1.0031.35N
ATOM6437CA TYRF163-16.731-10.77615.562 1.00 31.24C
ATOM6438CB TYRF163-17.992-11.08916.367 1.0031.73C
ATOM6439CG TYRF 163-19.256-11.06915.535 1.00 32.04C
ATOM6440CDl TYR F 163-19.796-12.24915.053 1.00 32.74C
ATOM6441CEl TYRF 163 -20.949-12.25414.284 1.00 34.24C
ATOM6442CZ TYRF 163 -21.576-11.07113.977 1.00 32.85C
ATOM6443OH TYRF 163-22.720-11.12813.213 1.00 34.67O
ATOM6444CR2TYRF 163-21.062 -9.87214.435 1.0033.15C
ΑΙΌΜ6445CD2 TYRF 163-19.895 -9.87515.216 1.00 30.88C
ATOM6446C TYRF 163-16.761 -11.56914.247 1.00 31.01C
ATOM6447O TYRF 163-17.273-11.10313.227 1.00 31.18O
ATOM6448N PHEF 164-16.251 -12.79214.283 1.00 30.76N
ATOM6449CA PIIEF 164-16.427-13.69713.154 1.0029.71C
ATOM6450CB PHEF 164-15.067-14.10312.535 1.00 30.14C
ATOM6451CG PHEF 164-14.188-14.94513.442 1.00 30.03C
ATOM6452CDl PHEF 164-13.300-14.35214.304 1.00 29.06C
ATOM6453CEl PHEF164 -12.505 -15.11915.130 1.0031.38C
ATOM6454CZ PHEF 164-12.585-16.47515.094 1.00 29.80C
ATOM6455CE2 PHE F 164 -13.471 -17.08514.245 1.0031.28C
ATOM6456CD2 PHEF 164-14.260-16.33213.418 1.0031.27C
ATOM6457C PHEF 164-17.302-14.89713.544 1.0029.54C
ATOM6458O PHEF 164-17.473-15.17414.716 1.00 28.35O
ATOM6459N ASNF 165-17.896-15.57912.568 1.0029.55N
ATOM6460CA ASNF 165-18.610-16.81312.863 1.00 30.24C
ATOM6461CB ASNF165-19.928-16.92412.066 1.00 30.48C
ATOM6462CG ASNF165 -20.997-15.92712.517 1.00 32.09C[0388]ATOM6463ODl ASNF 165-21.503-15.15811.703 1.00 34.61O
ATOM6464ND2ASNF 165 -21.348 -15.93813.798 1.0031.22N
ATOM6465C ASNF 165-17.707-18.02812.620 1.00 30.25C
ATOM6466O ASNF 165-16.840-18.01211.745 1.00 29.87O
ATOM6467N SERF 166-17.880-19.07713.411 1.00 30.83N ATOM6468CA SERF 166-17.134-20.30213.124 1.0031.99C
ATOM6469CB SERF 166-15.794-20.34713.876 1.00 31.79C
ATOM6470OG SERF 166-14.971 -21.38613.350 1.00 29.94O
ATOM6471C SERF 166-17.909 -21.56513.444 1.00 32.88C
ATOM6472O SERF 166-18.683-21.59714.393 1.00 32.78O
ATOM6473N GLNF 167-17.654-22.62412.692 1.00 34.16N
ATOM6474CA GLNF 167-18.237-23.91113.072 1.00 36.86 C
ATOM6475CB GLNF 167-19.660 -24.08712.478 1.00 36.45 C
ATOM6476CG GLNF 167-19.705 -24.32510.986 1.00 36.86 C
ATOM6477CD GLNF 167-21.127-24.44210.500 1.00 37.63 C
ATOM6478OEl GLNF167-21.960-25.07811.154 1.00 37.51O
ATOM6479NE2 GLN F 167 -21.429 -23.7969.378 1.00 36.46N
ATOM6480C GLNF 167-17.341 -25.08112.721 1.00 37.53C
ATOM6481O GLNF 167-16.380-24.93411.983 1.00 37.31O
ATOM6482N ARG F 168-17.686 -26.24713.250 1.00 39.60N
ATOM6483CA ARGF 168-16.888-27.45713.084 1.00 41.42 C
ATOM6484CB ARGF 168-17.611 -28.60213.754 1.0040.83 C
ATOM6485CG ARGF168-16.780 -29.78814.051 1.00 39.88 C
ATOM6486CD ARGF 168-17.714-30.94613.925 1.00 42.86 C
ATOM6487NE ARGF 168-17.138-32.19214.389 1.00 42.54 N
ATOM6488CZ ARGF168-17.479 -32.78415.528 1.0041.94 C
ATOM6489NHl ARGF 168 -18.395 -32.22916.314 1.00 39.43N
ATOM6490NH2ARGF 168-16.899-33.93115.873 1.0041.14N
ATOM6491C ARGF 168-16.668 -27.78811.634 1.00 43.47C
ATOM6492O ARG F 168-17.582 -27.64310.816 1.00 44.05O
ATOM6493N GLUF 169-15.464-28.23811.299 1.00 46.32N
ATOM6494CA GLUF 169-15.193 -28.6269.919 1.0049.15 C
ATOM6495CB GLUF 169-13.823-28.1339.432 1.0049.12C
ATOM6496CG GLU F 169-13.912-27.6587.962 1.0051.47 C
ATOM6497CD GLUF 169-12.590 -27.6097.247 1.00 53.56 C
ATOM6498OEl GLUF 169-12.531 -28.1376.121 1.00 53.93O
ATOM6499OE2 GLUF 169-11.612-27.0427.799 1.0055.65O
ATOM6500C GLUF 169-15.386 -30.1209.635 1.00 50.79C
ATOM6501O GLUF 169-14.729 -30.97510.250 1.0051.41O
ATOM6502N ALAF 170-16.324-30.3988.718 1.00 52.68N
ATOM6503CA ALAF 170-16.597 -31.7258.111 1.00 53.65C
ATOM6504CB ALAF 170-16.913-31.5506.591 1.0054.21C
ATOM6505C ALAF 170-15.551 -32.8548.312 1.00 54.40C
ATOM6506O ALAF 170-15.932 -33.9748.699 1.00 54.52O
[0389]ATOM6550O GLUG510.899-20.126 -26.4371.00 55.96O
ATOM6551N ASNG611.695 -22.077 -27.2581.00 54.29N
ATOM6552CA ASNG610.783 -22.928 -26.4851.00 52.67C
ATOM6553CB ASNG611.031-24.401 -26.8081.00 52.85C
ATOM6554CG ASNG610.459 -24.802-28.1641.00 54.58C
ATOM6555ODl ASNG69.391 -24.338 -28.5591.00 55.64O
ATOM6556ND2ASNG611.168 -25.675 -28.8811.00 57.12N
ATOM6557C ASNG610.771 -22.668 -24.9591.0051.01C ATOM6558O ASNG69.708 -22.685 -24.3291.0049.92O
ATOM6559N VALG711.948 -22.392-24.3901.0049.67N
ATOM6560CA VALG712.085 -22.058-22.9681.0048.01C
ATOM6561CB VALG713.586-22.063-22.5151.00 48.54C
ATOM6562CGl VALG713.794-21.381 -21.1281.0047.90C
ATOM6563CG2VALG714.126 -23.486-22.4851.0048.70C
ATOM6564C VALG711.438-20.714-22.6821.00 46.97C
ATOM6565O VALG710.713-20.550-21.6881.0046.93O
ATOM6566N TYRG811.702-19.756 -23.5671.0045.84N
ATOM6567CA TYRG811.242-18.380-23.4021.00 44.40C
ATOM6568CB TYRG811.853-17.477 -24.4841.00 44.25C
ATOM6569CG TYRG811.452-16.030-24.3261.00 43.54C
ATOM6570CDl TYRG810.370-15.491 -25.0521.0042.25C
ATOM6571CE ITYR G89.983-14.158-24.8891.00 42.20C
ATOM6572CZ TYRG810.688-13.359 -23.9931.00 43.78C
ATOM6573OH TYRG810.336-12.038-23.7811.00 45.13O
ATOM6574CE2TYRG811.761 -13.882 -23.2701.00 43.36C
ATOM6575CD2 TYR G812.133-15.204 -23.4371.0042.09C
ATOM6576C TYRG89.716-18.340 -23.4761.00 43.81C
ATOM6577O TYRG89.057-17.623 -22.7211.00 42.85O
ATOM6578N METG99.176-19.126-24.4031.0043.17N
ATOM6579CA METG97.752-19.237-24.5771.00 42.90C
ATOM6580CB METG97.456-19.909-25.9051.00 43.70C
ATOM6581CG METG97.738-18.996-27.1021.0045.99C
ATOM6582SD METG96.806-17.433 -27.0601.00 51.44S
ATOM6583CE METG95.136-18.043 -27.3131.00 50.14C
ATOM6584C METG97.077-19.946 -23.4071.0042.22C
ATOM6585O METG95.950-19.629 -23.0581.0042.03O
ATOM6586N ALAG107.780 -20.883 -22.7741.0041.98N
ATOM6587CA ALAG107.263 -21.534-21.5561.0041.18C
ATOM6588CB ALAG108.121 -22.732-21.1531.00 40.64C
ATOM6589C ALAG107.154 -20.534-20.4041.0040.46C
ATOM6590O ALAG106.218-20.596-19.6141.0040.42O
ATOM6591N LYSG118.100-19.607 -20.3261.00 39.87N
ATOM6592CA LYSG118.087-18.588-19.2881.00 39.61C
ATOM6593CB LYSG119.423-17.849-19.2681.00 40.48C
[0391]ATOM 6608 2 ALAG 13 4.058-18.341-21.076 1.00 35.80¾ ATOM 6609 CA ALAG 13 2.836-19.078-2P742 1.00 35.75 O ATOM 6610 CB ALAG 13 20094,20.448-2.370 1.00 35.30 n ATOM 6611 C ALAG 13 2.642-19.176-19226 1.00 35.34 O ATOM 6612 O ALAG 13 1.528-19026-18.718 1.00 35.44 O ATOM 66132:GLUG M 3.737-19.375-18.4900l—*8isz. ATOM 66MOA GLUG M 3.694-19.3100-17.028 一0034 73 O ATOM 6615 Oro GLUG U 5.075-19.551 ,16.441 1.00 34.27 O ATOM 6616 CG GLUG 14 5.058-19.668-14.948 100 34.81 C ATOM 6617 CD GLUG 14 6.425-19.892-14.373 1.00 3537 C ATOM 6618oeslug M 7.427-19.433-14.980 10035.34 O ATOS 6619 OE2GLUG 14 6.486—2P559-13.317 100 36.70 O ATOM 6620 C GLUG 14 3.150-17.999-16.493 100 34.57 O ATOM 6621 O GLUG 14 2.429-17.952-15.492 1.00 34.65 O ATOM 6622 N GLNG 15 3.522-16.929-17.170 100 35.10¾ ATOM 6623 CA GLNG 15 3.126-15.586-16.795 1.00 35.64n ATOM 6624 CB GLNG 15 3.986-14.587-17.553 100 36.15 O ATOM 6625 CG GLNG 15 4.464-13.451 -16.677 1.0040.61 Π ATOM 6626 CD GLZG 15 5.653-13.846-15.879 1.0044.49 C ATOM 6627 OEl GLNG 15 6.705-14·155-16.439 1.00 48.55 O ATOM 6628 NE2GLNG 15 5.509-13.846-14.556 1.00 45000 ^ ATOM 6629 C GLNG 15 L653-15357-17J07 1.00 34.36 O ATOM 6630 O GLNG 15 0.893-14.815-16.281 1.00 34.41 O ATOM 6631¾ALAG 16 1.276-15.780-18.312 100 33.05 M ATOM 6632 CA ALAG 16 -0099-15.766-18.799 1.0032J5 n ATOM 6633 CB ALAG 16 -0.121 -16.069-20.316 1.0031.20 C ATOM 6634 O ALAG 16 -1015-16.732-18.037 1.00 31.24 O ATOM 6635 O ALAG 16 -2.232-16.601 -18.100 1.0031.58 O ATOM 6636 Z GLUG 17 -0.411-17.689-5¾ 100 3P68¾ ATOM 6637 门 A GLUG 17 —一.096-18.757-16.5M 1.0029.28 nt0392uATOM6638CB GLUG17-1.929-18.187-15.4431.0029.72C
ATOM6639CG GLUG17-1.136-17.167-14.6201.0033.96C
ATOM6640CD GLUG17-1.712-16.970-13.2701.00 39.20C
ATOM6641OEl GLU G17-2.946-16.785-13.1581.00 41.23O
ATOM6642OE2 GLU G17-0.919-17.022-12.3181.00 43.06O
ATOM6643C GLUG17-1.877-19.675-17.5121.00 28.68C
ATOM6644O GLUG17-3.014-20.068-17.2491.00 27.92O
ATOM6645N ARGG18-1.204-20.029-18.5931.00 28.46N
ATOM6646CA ARGG18-1.717-20.906-19.643 1.00 29.00C
ATOM6647CB ARGG18-1.598-20.197 -21.0041.0028.75C
ATOM6648CG ARGG18-2.489-18.952 -21.166 1.00 30.50C
ATOM6649CD ARGG18-2.661 -18.595 -22.624 1.00 32.21C
ATOM6650NE ARGG18-4.070-18.398 -22.8441.00 35.40N
ATOM6651CZ ARGG18-4.791 -18.932 -23.8181.0032.58C
ATOM6652NHl ARG G18-6.070-18.658-23.8511.00 34.27N
ATOM6653NH2ARGG18-4.256-19.665 -24.7681.00 29.94N
ATOM6654C ARGG18-0.804 -22.107-19.6091.00 28.54C
ATOM6655O ARGG180.127 -22.206 -20.3921.0029.10O
ATOM6656N TYRG19-1.052 -22.990-18.6521.00 28.43N
ATOM6657CA TYRG19-0.131 -24.043-18.2991.0027.43C
ATOM6658CB TYRG19-0.440-24.553-16.8951.0027.40C
ATOM6659CG TYR G19-0.231 -23.476-15.8811.0026.30C
ATOM6660CDlTYR G191.002-22.847-15.7601.00 26.26C
ATOM6661CEl TYRG191.180 -21.815-14.8521.0025.58C
ATOM6662CZ TYRG190.112-21.423-14.0791.0026.82C
ATOM6663OH TYRG19 0.254-20.423-13.170 1.00 28.07O
ATOM6664CE2TYRG19-1.124-22.018-14.2111.00 25.62C
ATOM6665CD2TYRG19-1.286 -23.027-15.1041.00 24.44C
ATOM6666C TYRG19-0.035-25.176-19.2551.00 28.26C
ATOM6667O TYRG191.030-25.768-19.3701.00 28.50O
ATOM6668N GLUG20-1.160 -25.512-19.9081.00 28.69N
ATOM6669CA GLUG20-1.186 -26.545 -20.9091.0029.32C
ATOM6670CB GLUG20-2.615-26.710-21.4761.0029.79C
ATOM6671CG GLUG20-3.613-27.189 -20.427 1.00 32.06C
ATOM6672CD GLUG20-4.386 -26.078-19.685 1.00 36.71C
ATOM6673OEl GLU G20-5.536-26.387-19.3161.00 38.39O
ATOM6674OE2GLUG20-3.879 -24.929-19.4521.00 40.24O
ATOM6675C GLUG20-0.165 -26.239-22.0021.00 29.49C
ATOM6676O GLUG200.575-27.137-22.4511.0029.60O
ATOM6677N GLUG21-0.137-24.974-22.4101.00 29.95N
ATOM6678CA GLUG21 0.844-24.441-23.338 1.0031.54C
ATOM6679CB GLUG21 0.420 -23.040 -23.810 1.0031.22C
ATOM6680CG GLUG21-0.779-23.051 -24.790 1.00 32.02C
ATOM6681CD GLUG21-1.423 -21.671 -24.998 1.0031.78C[0393]ATOM6682OEl GLU G 21-2.307 -21.569 -25.8791.00 29.55O
ATOM6683OE2GLUG 21-1.040 -20.689 -24.3131.00 30.26O
ATOM6684C GLUG 212.256 -24.361 -22.7321.0032.51C
ATOM6685O GLUG 213.247-24.421 -23.4591.00 32.08O
ATOM6686N METG 222.349 -24.173 -21.4211.00 33.41N
ATOM6687CA METG 22 3.649 -24.181-20.7431.00 34.76C
ATOM6688CB METG 223.519-23.735-19.2831.00 34.18C ATOM6689CG METG 22 4.827-23.293-18.6651.00 32.56C
ATOM6690SD METG 224.654 -23.240-16.8881.00 32.61S
ATOM6691CE METG 226.355 -22.887-16.4111.0029.47C
ATOM6692C METG 224.224 -25.591 -20.7941.00 36.89C
ATOM6693O METG 225.438 -25.762 -20.9071.0037.00O
ATOM6694,N VALG 233.343 -26.596 -20.7151.00 38.61N
ATOM6695CA VALG 233.772-27.985 -20.8371.0040.38C
ATOM6696CB VALG 232.607 -28.997 -20.5861.0040.16C
ATOM6697CGl VALG 232.906 -30.355 -21.1941.0040.52C
ATOM6698CG2VALG 232.316-29.141 -19.1231.0040.10C
ATOM6699C VALG 234.359 -28.166 -22.2391.00 41.40C
ATOM6700O VALG 235.560 -28.415-22.3861.00 42.28O
ATOM6701N GLIJ G 243.513-27.992-23.2531.0042.34N
ATOM6702CA GLUG 243.868 -28.193 -24.6541.00 43.46C
ATOM6703CB GLUG 242.820 -27.573 -25.5781.0043.01C
ATOM6704CG GLUG 24 1.464 -28.230 -25.4801.00 44.20C
ATOM6705CD GLUG 240.385 -27.500 -26.2761.00 45.61C
ATOM6706OEl GLU G 240.542 -26.289 -26.5351.00 50.96O
ATOM6707OE2 GLU G 24-0.626 -28.136-26.6491.00 48.36O
ATOM6708C GLUG 245.247 -27.673 -25.0121.00 43.77C
ATOM6709O GLUG 245.979-28.336-25.7531.0043.90O
ATOM6710N TYR G 255.599 -26.502 -24.4771.0044.34N
ATOM6711CA TYRG 256.860 -25.842 -24.8051.0044.94C
ATOM6712CB TYRG 256.861 -24.354 -24.4351.0045.48C
ATOM6713CG TYRG 256.066 -23.446 -25.3531.0046.21C
ATOM6714CDl TYRG 256.263 -23.455 -26.7411.00 47.68C
ATOM6715CEl TYRG 255.521 -22.604 -27.5931.0048.25C
ATOM6716CZ TYRG 254.595 -21.722 -27.0331.0048.69C
ATOM6717OH TYRG 25 3.855 -20.875 -27.8301.00 48.00O
ATOM6718CE2TYRG 254.400 -21.689 -25.6501.00 48.90C
ATOM6719CD2TYRG 255.140 -22.541 -24.8241.0047.91C
ATOM6720C TYRG 257.989-26.517-24.0781.00 45.51C
ATOM6721O TYRG 259.050 -26.777 -24.6581.00 45.15O
ATOM6722N METG 267.751 -26.781 -22.7931.0045.55N
ATOM6723CA METG 26 8.715-27.454-21.9601.00 45.31C
ATOM6724CB METG 26 8.251-27.504-20.5061.00 44.69C
ATOM6725CG METG 26 8.633-26.298-19.7391.00 42.29C
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ATOM6946C GLYG55 -4.735 -28.898 -9.964 1.0027.92C
ATOM6947O GLYG55 -5.563-28.939 -9.041 1.00 28.54O
ATOM6948N ALAG56 -5.042-28.400-11.155 1.00 27.34N
ATOM6949CA ALAG56 -6.325 -27.842-11.405 1.0027.12C
ATOM6950CB ALAG56 -6.272-26.939-12.641 1.0027.36C
ATOM6951C ALAG56 -7.362 -28.971 -11.535 1.00 26.95C
ATOM6952O ALAG56 -8.464-28.851 -10.998 1.0027.30O
ATOM6953N ARGG57 -6.984 -30.082-12.167 1.0026.49N
ATOM6954CA ARGG 57 -7.852 -31.296-12.263 1.00 26.44C
ATOM6955CB ARGG 57 -7.373 -32.257-13.383 1.0026.64C
ATOM6956CG ARGG 57 -7.719-31.859-14.862 1.00 25.85C
ATOM6957CD ARGG 57 -6.923 -30.648-15.327 1.0027.59C
ATOM6958NE ARGG57 -7.301-30.084-16.638 1.0024.31N
ATOM6959CZ ARGG57 -6.672-29.051 -17.193 1.00 29.31C
ATOM6960NH1ARGG57 -7.088 -28.583-18.363 1.0028.09N
ATOM6961NH2ARGG57 -5.605 -28.470-16.584 1.0023.05N
ATOM6962C ARGG57 -7.968 -32.045 -10.921 1.0026.07C
ATOM6963O ARGG57 -9.011 -32.657-10.635 1.0025.90O
ATOM6964N ARGG58 -6.909-31.979-10.104 1.0024.47N
ATOM6965CA ARGG 58 -6.888-32.656 -8.819 1.00 24.58C
ATOM6966CB ARGG58 -5.443 -32.725 -8.158 1.0024.70C
ATOM6967CG ARGG 58 -4.374-33.842 -8.647 1.00 22.11C
ATOM6968CD ARGG 58 -3.399 -34.319 -7.441 1.00 23.19C
ATOM6969NE ARGG58 -2.518-33.232 -7.139 1.0021.94N
ATOM6970CZ ARGG58 -1.693 -33.064 -6.100 1.0016.07C
ATOM6971NH1ARGG58 -1.535 -33.891 -5.038 1.00 11.81N
ATOM6972NH2ARGG58 -1.044-31.966 -6.164 1.0014.39N
ATOM6973C ARGG58 -7.882 -31.897 -7.919 1.0024.81C
ATOM6974O ARGG58 -8.624 -32.512 -7.179 1.00 24.68O
ATOM6975N ALAG59 -7.883 -30.562 -7.988 1.0025.61N
ATOM6976CA ALAG59 -8.782-29.727 -7.196 1.0026.14C
ATOM6977CB ALAG59 -8.284-28.279 -7.163 1.0025.05C
ATOM6978C ALAG59-10.245 -29.768 -7.693 1.00 26.79C
ATOM6979O ALAG59-11.172 -29.684 -6.902 1.00 27.73O
ATOM6980N SERG60-10.439-29.833 -8.993 1.00 27.23N
ATOM6981CA SERG60-11.765 -30.054 -9.558 1.0028.28C
ATOM6982CB SERG60-11.697 -29.959-11.065 1.0027.99C
ATOM6983OG SERG60-11.336-28.649-11.432 1.00 28.57O
ATOM6984C SERG60-12.321 -31.413 -9.165 1.00 29.36C
ATOM6985O SERG60-13.483 -31.516 -8.804 1.00 30.53O
ATOM6986N TRPG61 -11.478 -32.444 -9.208 1.00 30.31N
ATOM6987CA TRPG61-11.875 -33.787 -8.864 1.00 30.10C
ATOM6988CB TRPG61 -10.752 -34.783 -9.185 1.0029.95C
ATOM6989CG TRPG61-11.159-36.232 -8.921 1.0029.90CATOM6990CDl TRPG 61 -11.771 -37.074 -9.797 1.00 28.60C
ATOM6991NElTRP G 61 -12.010-38.282 -9.208 1.00 28.35N
ATOM6992CE2TRPG 61 -11.586 -38.244 -7.907 1.00 27.81C
ATOM6993CD2TRPG 61 -11.019-36.967 -7.692 1.00 29.43C
ATOM6994CE3TRPG 61 -10.483 -36.665 -6.426 1.00 30.01C
ATOM6995CZ3TRPG 61 -10.526 -37.646 -5.434 1.00 29.59C
ATOM6996CH2TRPG 61 -11.075 -38.934 -5.699 1.00 30.55C ATOM6997CZ2TRPG 61 -11.604 -39.242 -6.922 1.00 26.95C
ATOM6998C TRPG 61 -12.332 -33.905 -7.404 1.0031.27C
ATOM6999O TRPG 61 -13.354-34.548 -7.135 1.00 30.75O
ATOM7000N ARGG 62-11.587 -33.284 -6.469 1.0031.99N
ATOM7001CA ARGG 62-11.915-33.351 -5.044 1.00 33.17 C
ATOM7002CB ARGG 62-10.934 -32.560 -4.194 1.00 33.37 C
ATOM7003CG ARGG 62 -9.797 -33.356 -3.673 1.00 37.26 C
ATOM7004CD ARGG 62 -8.614-33.025 -4.462 1.0041.07 C
ATOM7005NE ARGG 62 -7.440 -32.956 -3.623 1.00 46.42 N
ATOM7006CZ ARGG 62 -6.338 -32.280 -3.927 1.00 49.12 C
ATOM7007NHl ARG G 62 -5.312-32.301 -3.081 1.00 52.12 N
ATOM7008NH2ARGG 62 -6.261 -31.578 -5.052 1.00 49.12 N
ATOM7009C ARGG 62-13.258-32.775 -4.744 1.00 33.82C
ATOM7010O ARGG 62-14.042-33.395 -4.028 1.00 33.70O
ATOM7011N ILEG 63-13.485 -31.551 -5.238 1.0035.02N
ATOM7012CA ILEG 63-14.776 -30.868 -5.119 1.00 36.30C
ATOM7013CB ILEG 63-14.740 -29.483 -5.794 1.00 36.49C
ATOM7014CGl ILE G 63-13.692 -28.603 -5.111 1.00 39.36C
ATOM7015CDl ILE G 63-13.290 -27.346 -5.894 1.00 43.64C
ATOM7016CG2ILEG 63-16.072-28.783 -5.647 1.00 37.97C
ATOM7017C ILEG 63-15.924 -31.729 -5.686 1.00 36.40C
ATOM7018O ILEG 63-16.956 -31.891 -5.047 1.00 36.29O
ATOM7019N VALG 64-15.724 -32.291 -6.869 1.00 37.16N
ATOM7020CA VALG 64-16.772-33.056 -7.557 1.00 38.08 C
ATOM7021CB VALG 64-16.371 -33.324 -9.032 1.00 37.76C
ATOM7022CGl VALG 64-17.318-34.320 -9.725 1.00 38.57C
ATOM7023CG2VALG 64-16.337 -32.003 -9.802 1.00 37.05C
ATOM7024C VALG 64-17.083 -34.326 -6.766 1.00 39.37C
ATOM7025O VALG 64-18.224 -34.791 -6.747 1.00 39.12O
ATOM7026N SERG 65-16.070 -34.855 -6.069 1.0040.59N
ATOM7027CA SERG 65-16.266 -36.027 -5.221 1.0042.01C
ATOM7028CB SERG 65-14.973 -36.798 -5.050 1.0041.99C
ATOM7029OG SERG 65-14.564-37.244 -6.319 1.0044.36 O
ATOM7030C SERG 65 -16.888 -35.766 -3.865 1.00 42.90C
ATOM7031O SERG 65 -17.478 -36.664 -3.284 1.0043.41O
ATOM7032N SERG 66-16.737 -34.553 -3.348 1.0044.00N
ATOM7033CA SERG 66-17.404-34.180 -2.114 1.00 44.99C
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ο Ζ6.9 寸 Os i·^' Sopigs Oo ssz, WOHV U(Nrs 寸 Os S.I- εΙ6·(Νε-66Γ9ι-99 opdWs S3 17SZ, WOlV
X 9ζεΑοοΐ < g 寸寸 ZSST ZoATOM7078OEl GLU G71 -27.650 -33.723 -4.5951.00 57.65O
ATOM7079OE2GLUG71 -26.334 -33.464 -2.8461.00 56.76O
ATOM7080C GLUG71 -25.994-38.133 -2.8571.00 57.46C
ATOM7081O GLUG71 -27.152 -38.529 -2.9111.00 57.48O
ATOM7082N GLUG72 -24.957 -38.949 -2.6571.00 58.36N
ATOM7083CA GLUG72 -25.121-40.381 -2.3411.00 59.54C
ATOM7084CB GLUG72 -23.799-41.153 -2.4481.00 59.24C
ATOM7085CG GLUG72 -23.347-41.420 -3.8701.00 59.87C
ATOM7086CD GLUG72 -21.982-42.094 -3.9681.00 60.67C
ATOM7087OEl GLUG72 -21.072-41.830 -3.1331.00 62.83O
ATOM7088OE2GLUG72 -21.811 -42.884 -4.9171.00 62.00O
ATOM7089C GLUG72 -25.698 -40.575 -0.9531.00 59.91C
ATOM7090O GLUG72-26.436-41.533 -0.7181.00 60.70O
ATOM7091N GLYG73 -25.342 -39.669 -0.0411.00 60.13N
ATOM7092CA GLYG73 -25.862 -39.669 1.3231.00 60.28C
ATOM7093C GLYG73 -27.246 -39.041 1.4421.00 60.34C
ATOM7094O GLYG73 -28.007 -39.392 2.3391.00 60.35O
ATOM7095N ARGG74 -27.564-38.102 0.5501.00 60.11N
ATOM7096CA ARGG74 -28.878 -37.462 0.528 1.00 59.89C
ATOM7097CB ARGG74 -28.787 -36.020 -0.0151.00 60.15C
ATOM7098CG ARGG74 -28.048 -35.023 0.911 1.00 61.87C
ATOM7099CD ARGG74-28.644-33.594 0.878 1.00 64.41C
ATOM7100NE ARGG74 -27.729 -32.576 1.4291.00 67.39N
ATOM7101CZ ARGG74-27.660 -32.193 2.7141.00 68.92C
ATOM7102NHl ARG G74 -28.459 -32.732 3.6361.00 69.23N
ATOM7103NH2ARGG74-26.781-31.260 3.0861.00 67.83N
ATOM7104C ARGG74 -29.903 -38.296 -0.2641.00 59.26C
ATOM7105O ARGG74 -31.044-37.870 -0.4601.00 59.42O
ATOM7106N GLYG75 -29.489 -39.484 -0.7021.00 58.50N
ATOM7107CA GLYG75 -30.313-40.362 -1.5381.00 57.60C
ATOM7108C GLYG75 -30.581 -39.923 -2.9721.00 56.92C
ATOM7109O GLYG75 -31.399 -40.530 -3.6551.00 56.81O
ATOM7110N ASNG76 -29.895 -38.884 -3.4451.00 56.66N
ATOM7111CA ASNG76 -30.227 -38.250 -4.7441.00 56.22C
ATOM7112CB ASNG76 -29.863 -36.760 -4.7311.00 56.42C
ATOM7113CG ASNG76 -30.688 -35.954 -3.7211.00 56.62C
ATOM7114ODl ASN G76 -30.545 -34.732 -3.6301.00 56.50O
ATOM7115ND2ASNG76 -31.551-36.633 -2.9651.00 57.69N
ATOM7116C ASNG76 -29.637 -38.949 -5.9731.00 55.61C
ATOM7117O ASNG76-28.621 -38.521 -6.5071.00 55.42O
ATOM7118N GLUG77 -30.312-40.009 -6.4201.00 55.00N
ATOM7119CA GLUG77 -29.800-40.925 -7.4361.00 54.50C
ATOM7120CB GLUG77 -30.818-42.048 -7.6981.00 54.71C
ATOM7121CG GLUG77-30.188 -43.399 -8.0951.00 55.60C
[0403]ATOM7122CD GLUG 77 -31.142-44.339 -8.864 1.00 55.52 CATOM7123OEl GLU G 77 -32.381-44.181 -8.7481.00 55.80O
ATOM7124OE2GLUG 77 -30.639 -45.245 -9.5721.00 55.40O
ATOM7125C GLUG 77 -29.460 -40.228 -8.7471.00 53.75C
ATOM7126O GLUG 77 -28.349 -40.389 -9.2841.00 53.40O
ATOM7127N GLUG 78 -30.426-39.465 -9.2581.00 52.71N
ATOM7128CA GLUG 78 -30.294-38.792-10.5501.00 52.13C
ATOM7129CB GLUG 78 -31.640 -38.208-10.9971.00 52.63C ATOM7130CG GLUG 78 -32.408 -37.466 -9.899 1.00 55.38 C
ATOM7131CD GLUG 78 -33.147 -36.237-10.4301.00 59.99C
ATOM7132OEl GLU G 78 -32.960-35.132 -9.8501.00 61.03O
ATOM7133OE2GLUG 78 -33.893 -36.370-11.4401.00 61.29O
ATOM7134C GLUG 78 -29.163 -37.731-10.5751.00 50.45C
ATOM7135O GLUG 78 -28.535-37.510-11.6061.00 50.15O
ATOM7136N HISG 79 -28.915-37.093 -9.4381.00 48.74N
ATOM7137CA HISG 79-27.767-36.190 -9.2741.00 47.31C
ATOM7138CB HISG 79 -27.846 -35.466 -7.9251.00 47.34C
ATOM7139CG HISG 79 -28.803 -34.316 -7.9251.00 48.01C
ATOM7140NDl HIS G 79 -29.052 -33.554 -6.8031.0048.68N
ATOM7141CEl HIS G 79-29.930-32.613 -7.1051.0048.18C
ATOM7142NE2 HIS G 79 -30.269 -32.748 -8.3761.0047.27N
ATOM7143CD2 HIS G 79 -29.582 -33.807 -8.9101.00 46.74C
ATOM7144C HISG 79 -26.473 -36.962 -9.3671.0046.02C
ATOM7145O HISG 79 -25.646 -36.709-10.2371.00 45.97O
ATOM7146N VALG 80-26.331 -37.926 -8.4611.0045.11N
ATOM7147CA VALG 80-25.236-38.891 -8.449 1.00 44.00C
ATOM7148CB VALG 80 -25.543 -40.062 -7.4801.0044.06C
ATOM7149CGl VALG 80-24.474-41.149 -7.5851.0044.82C
ATOM7150CG2VALG 80-25.629 -39.551 -6.0581.0043.72C
ATOM7151C VALG 80 -24.846 -39.402 -9.8511.0043.28C
ATOM7152O VALG 80-23.653 -39.454-10.1791.0042.94O
ATOM7153N THRG 81 -25.843-39.757-10.6681.0041.66N
ATOM7154CA IHRG 81-25.588-40.268-12.0091.00 40.73C
ATOM7155CB THRG 81-26.892-40.708-12.6841.0041.05C
ATOM7156OGl THRG 81 -27.477-41 _746-11.9001.00 41.91O
ATOM7157CG2THRG 81 -26.646-41.216-14.1221.0040.38C
ATOM7158C THRG 81 -24.883 -39.239-12.8811.00 39.97C
ATOM7159O THRG 81 -23.961 -39.569-13.6231.00 39.29O
ATOM7160N LEUG 82 -25.333 -37.993 -12.7751.0039.83N
ATOM7161CA LEUG 82 -24.783 -36.895-13.5521.00 39.30C
ATOM7162CB LEUG 82-25.762 -35.717-13.5541.00 39.49C
ATOM7163CG LEUG 82 -27.125 -35.924-14.2551.00 37.99C
ATOM7164CDl LEU G 82 -28.143 -34.913-13.7621.0034.81C
ATOM7165CD2LEUG 82 -27.006 -35.857-15.7591.0035.56C
[0404]ATOM7166 C LEUG 82 -23.402 -36.486-13.012 1.00 39.21CATOM7167 O LEUG 82 -22.473 -36.280-13.791 1.0038.33O
ATOM7168N ILEG 83 -23.276 -36.419-11.688 1.00 39.28N
ATOM7169 CA ILEG 83 -22.001 -36.132-11.041 1.00 40.03C
ATOM7170 CB ILEG 83 -22.146-35.988 -9.499 1.0040.00C
ATOM7171CGl ILEG 83 -23.159 -34.912 -9.183 1.00 39.65C
ATOM7172CDl ILEG 83 -23.666 -34.941 -7.790 1.0043.10C
ATOM7173CG2ILEG 83 -20.813 -35.559 -8.861 1.0040.08C·ATOM7174C ILEG 83-20.928 -37.164-11.400 1.0040.46C
ATOM7175O ILEG 83-19.760 -36.808-11.646 1.00 41.03O
ATOM7176N ARGG 84 -21.331 -38.427-11.453 1.0040.26N
ATOM7177CA ARGG 84 -20.412-39.523-11.716 1.0040.64C
ATOM7178CB ARGG 84 -21.117-40.875-11.477 1.00 41.70C
ATOM7179CG ARGG 84-20.296 -42.140-11.783 1.0044.53C
ATOM71BOCD ARGG 84-20.810-43.302-10.963 1.00 50.83C
ATOM7181NE ARGG 84 -20.955 -42.880 -9.562 1.00 56.50 N
ATOM7182CZ ARGG 84 -21.565-43.568 -8.595 1.00 57.41 C
ATOM7183NHl ARG G 84 -22.123 -44.753 -8.836 1.00 57.53N
ATOM7184NH2ARGG 84 -21.621 -43.048 -7.375 1.00 58.12N
ATOM7185C ARGG 84-19.866 -39.435-13.131 1.0040.10C
ATOM7186O ARGG 84-18.665 -39.610-13.348 1.00 39.15O
ATOM7187N GLUG 85 -20.745 -39.161 -14.100 1.00 39.39N
ATOM7188CA GLUG 85-20.282 -39.012-15.484 1.00 39.47C
ATOM7189CB GLUG 85 -21.447 -39.037-16.500 1.00 39.82C
ATOM7190CG GLUG 85-22.515-40.197-16.276 1.0043.71C
ATOM7191CD GLUG 85-21.953 -41.632-15.984 1.00 48.10C
ATOM7192OEl GLU G 85 -21.002-42.096-16.674 1.0049.43O
ATOM7193OE2GLUG 85 -22.495 -42.309-15.062 1.00 48.62O
ATOM7194C GLUG 85 -19.361 -37.793 -15.678 1.00 37.93C
ATOM7195O GLUG 85-18.524-37.783-16.565 1.0038.14O
ATOM7196N TYRG 86-19.538-36.782-14.836 1.00 36.53N
ATOM7197CA TYRG 86-18.703 -35.573-14.827 1.00 35.53C
ATOM7198CB TYRG 86-19.448 -34.443-14.081 1.00 34.72C
ATOM7199CG TYRG 86-18.844-33.079-14.296 1.00 34.12C
ATOM7200CDl TYRG 86-18.915-32.449-15.547 1.00 32.12C
ATOM7201CEl TYR G 86-18.344 -31.193-15.762 1.00 32.11C
ATOM7202CZ TYRG 86-17.683 -30.562-14.710 1.00 33.38C
ATOM7203OH TYRG 86-17.122-29.333-14.897 1.0031.84O
ATOM7204CE2TYRG 86-17.604-31.157-13.460 1.00 33.84C
ATOM7205CD2TYRG 86-18.184-32.414-13.251 1.00 33.53C
ATOM7206C TYRG 86-17.300 -35.866-14.233 1.00 34.63C
ATOM7207O TYRG 86-16.261-35.589-14.855 1.00 33.75O
ATOM7208N ARGG 87-17.291-36.484-13.055 1.00 34.48N
ATOM7209CA ARGG 87-16.060 -36.967-12.460 1.00 34.91C
[0405]UD L[90170]
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M83'8£00'1 890'6- Sl8'6£-0^'9l-Z.8 OO^V 3Ni\ZLJAIOIV
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D私_1/£00_1 £St7OI-£ir8£-l7erSI-Z,8 OOW 93WZLIAIOIVATOM 7268 CD2LEUG 94 -6.444-35051 -12.743 100 23005 C ATOM 7269 C LEUG 94 -5.285-37.904-15.631 100 29.67 n ATOM 7270 O LEUG 94 -4.070-37.801 -15.599 1.00 28.80 〇 ATOM 7271 ^ SERG 95 -5.907-38.982-16.118 1.00 30.872: ATOM 7272 CA SERG 95 -5.197-40.139-16.652 1.00 31.58 n ATOM 7273 S SERG 95 -6.179-41.249-17064 100 31.88 n ATOM 7274 OG SERG 95 -7.103-41.547-16.039 ioo 32.77 O ATOM 7275 C SERG 95 ,4 334.39 756-17.844 1003Z10 O ATOM 7276 O SERG 95 -3.262—40.291-18021 1.00 33.57 O ATOM 7277 ^ LYSG 9·6 -4.803-38.825-18.653 1.00 33.07 ^ ATOM 727如 CA LYSG 96 -4060-38.333-19.807 1.00 33002 C ATOM 7279 CB LYSG 96 -5.026-37.609-20.754 1.00 33.97 n ATOM 7280 OQ LYSG 96 -4.365-36.860-21.887 1.00 38.25 n ATOM 7281 CD LYSG 96 -5.225-35.662-22.336 100 44.35 C ATOM 7282 OM iQ 96 -4.362-34.456-22.7¾ roo n ATOM 7283 NZ LYSG 96 -3.388-33.993-21.651 1.0047.44¾ ATOM 728私 O LYSG 96 -20079-37.421-19.442 1.00 33·67 C ATOM 7285 O LYSG 96 -1.839-37.464-20.084 1.00 33.71 〇 ATOM 7286¾ILEG 97 -3059-36.564-18.444 100 33.57¾ ATOM 7287 CA ILmG 97 -1.986-35.681-17.990 1.00 33.42 C ATOM 7288 οω ILEG 97 -2.493-34.596-16.980 1.00 33.76O ATOM 72snspWG 97 -3.588-33.717-17.618 C ATOM 7290 CDl ILE G 97 -4.546-33.096-16‘so 100 30.05 O ATOM 7291 CG2ILEG 97 -L318-33.706-16.494 1.003309 n ATOM 7292 C ILEG 97 -0.825-36.488-17.393 1.00 33J0 O ATOM 7293 〇 ILEG 97 0325-36.310-17.806 1.00 33.81 〇 ATOM 7294 N CYSG 98 -1.140-37.373-16.447 1.00 32.21 ^ ATOM 7295 CA CYSG 900Io-S 100 31.88 C ATOM 7296 CB CYSG 98 丨0.898-39.283-14.934 1.00 3101 C ATOM 7297 SGnYSG 妄 —一 5g—3ggs_13.404 1.00 31.49 S
t0407u
191ATOM7298C CYSG 98 0.539-39.094-16.952 1.00 32.62 C
ATOM7299O CYSG 98 1.767 -39.218-16.9411.00 33.05 O
ATOM7300N ASPG 99-0.240-39.640-17.8901.00 33.14N
ATOM7301CA ASPG 99 0.281-40.437-18.999 1.00 33.06 C
ATOM7302CB ASPG 99-0.875 -40.888-19.942 1.00 34.31 C
ATOM7303CG ASPG 99-0.431 -41.926 -20.941 1.00 36.93 C
ATOM7304ODl ASP G 99-0.555-43.127-20.6321.00 41.28O
ATOM7305OD2ASPG 990.089-41.548 -22.0101.00 39.97O
ATOM7306C ASPG 991.351 -39.707-19.7731.0031.94C
ATOM7307O ASPG 992.370-40.283 -20.0871.00 32.76O
ATOM7308N GLYG1001.121 -38.441 -20.0901.0031.59N
ATOM7309CA GLY G100 2.090-37.656-20.848 1.0030.82 C
ATOM7310C GLYG1003.438-37.536-20.1391.00 30.82C
ATOM7311O GLYG1004.493 -37.795 -20.7261.00 30.54O
ATOM7312N ILE G1013.408 -37.135-18.8771.0030.27N
ATOM7313CA ILE G 1014.661 -36.940-18.0991.0029.72C
ATOM7314CB ILE G1014.443 -35.986-16.8861.0029.32C
ATOM7315CGl ILE G1015.732 -35.781 -16.0611.0028.45C
ATOM7316CDl ILE G1016.905 -35.237-16.8771.0024.48C
ATOM7317CG2ILEG1013.253-36.445-16.0301.0029.21C
ATOM7318C ILEG 1015.329-38.284-17.7031.0029.71C
ATOM7319O ILE G1016.556-38.384-17.7441.0029.17O
ATOM7320N LEU G1024.534 -39.309-17.3791.00 30.02N
ATOM7321CA LEU G102 5.076 -40.646-17.075 1.00 30.45 C
ATOM7322CB LEUG102 4.004-41.599-16.5111.0029.91C
ATOM7323CG LEU G102 3.535-41.363-15.070 1.00 29.35 C
ATOM7324CDl LEU G1024.696-41.421-14.0401.00 26.68C
ATOM7325CD2LEUG1022.421 -42.320 -14.7001.00 28.71C
ATOM7326C LEU G1025.784 -41.295-18.2741.0031.49C
ATOM7327O LEU G1026.819-41.951-18.1081.0031.59O
ATOM7328N LYS G1035.234 -41.088-19.4781.00 32.79N
ATOM7329CA LYS G1035.831-41.572-20.7321.00 33.39C
ATOM7330CB LYSG 1034.907 -41.315-21.9131.00 32.58C
ATOM7331CG LYS G1034.062-42.527-22.3351.00 36.19C
ATOM7332CD LYS G1032.888 -42.098 -23.2421.00 36.29C
ATOM7333CE LYS G1033.303 -41.030 -24.2961.00 41.25C
ATOM7334NZ LYSG1032.159 -40.493 -25.1341.0041.38N
ATOM7335C LYS G1037.132 -40.888-20.9991.00 32.27C
ATOM7336O LYS G1038.075-41.506-21.4501.00 32.81O
ATOM7337N LEUG1047.172 -39.597 -20.7391.0031.78N
ATOM7338CA LEUG 104 8.388 -38.831-20.937 1.0031.70 C
ATOM7339CB LEU G104 8.056 -37.342 -21.0251.0031.94 C
ATOM7340CG LEU G104 9.227 -36.405 -21.303 1.00 32.58 C
ATOM7341CDl LEUG1049.666 -36.539 -22.7371.0031.82C
[0408]ATOM7342CD2 LEU G 104 8.880 -34.943 -20.9761.00 32.33CATOM7343C LEUG104 9.460-39.099-19.8611.00 30.74C
ATOM7344O LEU G104 10.652 -39.066 -20.1571.0031.02O
ATOM7345N LEUG 105 9.042-39.351-18.6231.0029.44N
ATOM7346CA LEU G 105 9.980 -39.752-17.5601.0027.70C
ATOM7347CB LEU G105 9.257 -39.869-16.2031.0026.76C
ATOM7348CG LEU G105 8.784 -38.573-15.5471.00 24.21C
ATOM7349CDl LEU G105 9.917-37.843-14.7461.00 22.23C·
ATOM7350CD2 LEU G 105 7.532 -38.807 -14.6481.00 25.43C
ΛΓΟΜ7351C LEUG105 10.641 -41.081 -17.9521.00 28.96C
ATOM7352O LEU G105 11.861-41.238-17.8681.00 27.25O
ATOM7353N ASPG106 9.815-42.020-18.4271.0031.16N
ATOM7354CA ASPG106 10.287 -43.333 -18.8371.00 33.08C
ATOM7355CB ASP G106 9.124-44.292-19.0081.00 34.57C
ATOM7356CG ASPG106 8.666-44.875-17.6971.00 36.90C
ATOM7357ODl ASP G106 9.261-44.516-16.6521.00 41.38O
ATOM7358OD2ASPG106 7.720-45.692-17.7211.00 40.30O
ATOM7359C ASPG106 11.174-43.369-20.0671.00 33.58C
ATOM7360O ASPG106 12.103-44.158-20.1171.00 33.26O
ATOM7361N SERG107 10.899 -42.506 -21.0381.00 34.89N
ATOM7362CA SERG107 11.601 -42.507-22.3181.00 35.90C
ATOM7363CB SERG107 10.672 -42.058-23.4541.00 35.93C
ATOM7364OG SERG107 10.476-40.653-23.4351.00 34.92O
ATOM7365C SERG107 12.850 -41.635-22.2961.00 36.57C
ATOM7366O SERG107 13.879 -42.013-22.8621.00 37.82O
ATOM7367N HTS G108 12.773-40.478 -21.6511.00 36.38N
ATOM7368CA HIS G108 13.844-39.488 -21.7701.00 36.40C
ATOM7369CB HIS G108 13.324-38.172 -22.3901.00 36.94C
ATOM7370CG HIS G108 13.025 -38.247 -23.8601.00 39.56C
ATOM7371NDl HISG 108 11.920-38.902-24.3681.0041.16N
ATOM7372CEl HIS G108 11.911 -38.791 -25.6851.0041.30C
ATOM7373NE2HISG108 12.965 -38.083 -26.0521.00 40.99N
ATOM7374CD2 HIS G108 13.673 -37.722 -24.9291.00 41.32C
ATOM7375C HIS G108 14.510-39.162-20.4501.00 35.33C
ATOM7376O HISG108 15.729-39.269-20.3341.00 35.11O
ATOM7377N LEU G109 13.697 -38.762-19.4671.00 34.56N
ATOM7378CA LEU G109 14.181 -38.078-18.2451.0033.63C
ATOM7379CB LEU G109 13.062-37.237-17.6161.00 33.13C
ATOM7380CG LEU G109 12.494 -36.121 -18.5001.00 33.12C
ATOM7381CDl LEU G109 11.185 -35.589-17.9441.00 30.28C
ATOM7382CD2LEUG109 13.516-35.006-18.6761.0031.25C
ATOM7383C LEU G109 14.791 -38.985-17.1911.00 33.28C
ATOM7384 O LEU G109 15.854 -38.662-16.6331.00 33.08O
ATOM7385N VALG 110 14.132 -40.099-16.8801.00 32.73N
[0409]ATOM7386CAVALG11014.750 -41.051 -15.9271.00 33.55CATOM7387CBVALG11013.774-42.137-15.3891.0033.54C
ATOM7388CGl VALG11014.432 -42.941 -14.2911.00 34.47C
ATOM7389CG2 VALG 11012.514-41.506-148341.00 32.98C
ATOM7390CVALG11016.023 -41.655-16.5581.00 33.73C
ATOM7391OVALG11017.093 -41.519-15.9681.00 34.32O
ATOM7392NPRO G 11115.923 -42.275 -17.7751.00 33.61N ATOM7393CAPRO G 11117.109-42.871-18.4221.0033.42C
ATOM7394CBPRO G 11116.581 -43.302-19.7901.00 33.17C
ATOM7395CGPROGin15.135-43.596-19.5341.0033.48C
ATOM7396CDPRO G 11114.699-42.540-18.5781.0033.45C
ATOM7397CPRO G 11118.330-41.979-18.6241.00 33.32C
ATOM7398OPRO G 11119.460-42.476-18.5811.00 33.15O
ATOM7399NSERG 11218.111 -40.699-18.8921.00 32.78N
ATOM7400CASERG11219.208 -39.831 -19.2591.00 32.76C
ATOM7401CBSERG 11218.686 -38.739-20.1681.00 32.85C
ATOM7402OG SERG11217.558-38.122-19.5781.00 34.83O
ATOM7403CSERG11219.927-39.226-18.0401.00 32.40C
ATOM7404OSERG 11220.962-38.575-18.1711.00 33.41O
ATOM7405NSERG 11319.357-39.447-16.8631.0031.54N
ATOM7406CASERG11319.868 -38.897-15.6401.0030.77C
ATOM7407CBSERG11318.853 -39.098-14.5171.00 30.23C
ATOM7408OG SERG 11317.845 -38.129-14.6051.0031.19O
ATOM7409CSERG11321.201-39.525-15.2631.0029.85C
ATOM7410OSERG 11321.277-40.733-15.0971.0029.19O
ATOM7411NTHRG11422.237 -38.698-15.1231.00 29.72N
ATOM7412CATHRG11423.569-39.201 -14.7341.00 30.47C
ATOM7413CBTHRG11424.688-38.646-15.6571.00 30.26C
ATOM7414OGl THRG11424.516-37.233 -15.8171.00 33.64O
ATOM7415CG2THRG11424.656 -39.296-17.0571.00 33.24C
ATOM7416CTHRG 11423.940 -38.946-13.2691.00 29.77C
ATOM7417OTHRG11424.686 -39.692 -12.6731.0029.65O
ATOM7418NALAG11523.429 -37.860 -12.7041.00 30.09N
ATOM7419CAALAG 11523.810-37.424-11.3751.0029.32C
ATOM7420CBALAG11523.971 -35.923-11.3541.0029.53C
ATOM742〗CALAG 11522.719-37.850-10.4251.00 29.49C
ATOM7422OALAG11521.611-38.184-10.8621.00 29.22O
ATOM7423NALAG11623.028 -37.816 -9.1311.0028.78N
ATOM7424CAALAG11622.125 -38.279 -8.071 1.00 28.57C
ATOM7425CBALAG11622.893 -38.404 -6.739 1.0027.85C
ATOM7426CALAG11620.887 -37.390 -7.9001.0028.58C
ATOM7427OALAG11619.799 -37.869 -7.6161.0029.08O
ATOM7428NGLUG 11721.043 -36.093 -8.0661.0028.83N
ATOM7429CAGLUG117 19.909-35.198 -7.907 1.0030.18C
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ATOM7518C GLYG1275.024 -40.726 -7.711 1.0021.23C
ATOM7519O GLYG1273.907 -41.103 -7.307 1.00 21.95O
ATOM7520N ASPG1285.302-39.427 -7.889 1.0019.80N
ATOM7521CA ASPG1284.219-38.371 -7.737 1.00 18.29C
ATOM7522CB ASPG1284.725 -36.979 -8.033 1.00 17.27C
ATOM7523CG ASPG1285.679-36.423 -6.943 1.00 18.19C
ATOM7524ODl ASP G1285.690 -36.928 -5.810 1.00 18.42O
ATOM7525OD2 ASPG1286.417 -35.469 -7.221 1.00 18.86O
ATOM7526C ASPG 1283.023 -38.656 -8.699 1.0019.31C
ATOM7527O ASPG1281.911 -38.647 -8.276 1.00 19.55O
ATOM7528N TYRG1293.296-38.851 -9.983 1.00 19.33N
ATOM7529CA TYR G1292.266 -38.995-11.018 1.00 19.86C
ATOM7530CB TYRG1292.812-38.606-12.434 1.00 18.73C
ATOM7531CG TYRG1293.007-37.136-12.459 1.0017.65C
ATOM7532CDl TYRG1294.186 -36.534-11.906 1.0022.70C
ATOM7533CEl TYRG1294.315-35.145-11.831 1.0012.05C
ATOM7534CZ TYRG1293.270-34.370-12.250 1.0019.22C
ATOM7535OH TYRG129 3.333-33.007-12.226 1.00 18.28O
ATOM7536CE2 TYRG1292.102-34.950-12.779 1.0015.29C
ATOM7537CD2TYRG1291.976 -36.309-12.804 1.0016.70C
ATOM7538C TYRG1291.585 -40.345-10.902 1.0020.25C
ATOM7539O TYRG1290.397 -40.371 -10.963 1.0023.35O
ATOM7540N HISG 1302.293 -41.444-10.625 1.00 21.43N
ATOM7541CA HIS G1301.613-42.700-10.255 1.0021.86C
ATOM7542CB HIS G1302.567 -43.880 -9.985 1.00 23.82C
ATOM7543CG HIS G1303.224-44.428-11.204 1.0025.16C
ATOM7544NDl HIS G1302.535-45.138-12.167 1.00 29.30N
ATOM7545CEl HIS G 1303.373-45.488-13.129 1.00 28.92C
ATOM7546NE2HISG1304.578 -45.041-12.817 1.00 27.84N
ATOM7547CD2HISG1304.507 -44.374-11.619 1.00 27.11C
ATOM7548C HIS G1300.733-42.518 -9.057 1.0021.80C
ATOM7549O HIS G130-0.379 -43.098 -8.983 1.0022.40O
ATOM7550N ARGG1311.187 -41.694 -8.124 1.00 19.15N
ATOM7551CA ARGG1310.406 -41.357 -6.923 1.0017.98C
ATOM7552CB ARG G1311.280-40.601 -5.849 1.0016.19C
ATOM7553CG ARGG1310.408 -39.979 -4.745 1.0014.76 C
ATOM7554CD ARG G 1311.242-39.583 -3.441 1.0018.84 C
ATOM7555NE ARG G1312.273 -38.598 -3.769 1.0015.78N
ATOM7556CZ ARGG1312.109-37.275 -3.710 1.0022.76C
ATOM7557NHl ARG G1310.921 -36.765 -3.326 1.0019.16N
ATOM7558NH2 ARGG1313.180 -36.447 -3.965 1.0021.81N
ATOM7559C ARGG131-0.827 -40.520 -7.149 1.0017.22C
ATOM7560O ARGG131-1.794-40.678 -6.413 1.00 16.45O
ATOM7561N TYRG132-0.747 -39.540 -8.052 1.0017.43N
[0413]ATOM7562CA TYRG132 -1.936 -38.831 -8.489 1.0019.09CATOM7563CB TYRG132 -1.586 -37.588 -9.347 1.0018.29C
ATOM7564CG TYRG132 -0.546 -36.662 -8.728 1.0016.07C
ATOM7565CDl TYRG132 0.287 -35.908 -9.529 1.0016.22C
ATOM7566CEl TYRG132 1.275 -35.032 -8.958 1.0015.76C
ATOM7567CZ TYRG132 1.441 -34.953 -7.594 1.0014.65C ATOM7568OH TYRG132 2.423 -34.097 -7.082 1.00 14.35O
ATOM7569CE2TYRG132 0.645 -35.716 -6.769 1.0014.24C
ATOM7570CD2TYRG132 -0.369 -36.581 -7.339 1.0015.82C
ATOM7571C TYRG132 -2.937 -39.769 -9.216 1.0020.04C
ATOM7572O TYRG132 -4.136 -39.474 -9.272 1.0021.98O
ATOM7573N LEU G133 -2.467 -40.885 -9.766 1.0021.90N
ATOM7574CA LEU G133 -3.396 -41.894-10.372 1.00 22.63C
ATOM7575CB LEUG133 -2.647 -42.865-11.297 1.0021.69C
ATOM7576CO LEUG133 -2.160 -42.361 -12.666 1.0021.54C
ATOM7577CDl LEUG 133 -1.309 -43.398-13.443 1.0017.58C
ATOM7578CD2LEUG133 -3.332 -41.927-13.532 1.0023.59C
ATOM7579C LEU G133 -4.028 -42.661 -9.237 1.0024.31C
ATOM7580O LEU G133 -5.216-42.891 -9.225 1.00 25.86O
ATOM7581N ALAG134 -3.251-42.987 -8.204 1.00 25.62N
ATOM7582CA ALAG134 -3.814-43.755 -7.102 1.0026.34C
ATOM7583CB ALAG134 -2.668 -44.396 -6.219 1.00 25.55C
ATOM7584C ALAG134 -4.821 -42.946 -6.263 1.00 27.11C
ATOM7585O ALAG134 -5.567-43.509 -5.447 1.0027.02O
ATOM7586N GLU G135 -4.824-41.616 -6.444 1.0028.38N
ATOM7587CA GLUG135 -5.821 -40.749 -5.817 1.0028.54C
ATOM7588CB GLU G135 -5.468 -39.289 -5.996 1.0027.89C
ATOM7589CG GLUG 135 -4.486 -38.792 -4.987 1.0026.70C
ATOM7590CD GLUG 135 -4.002 -37.429 -5.336 1.0024.86C
ATOM7591OEl GLUG135 -3.075 -36.929 -4.646 1.0021.11O
ATOM7592OE2GLUG135 -4.583 -36.839 -6.288 1.00 21.90O
ATOM7593C GLUG135 -7.241 -40.964 -6.332 1.0029.68C
ATOM7594O GLU G135 -8.161 -40.942 -5.539 1.00 30.74O
ATOM7595N PHE G136 -7.423 -41.176 -7.632 1.00 30.72N
ATOM7596CA PHE G136 -8.773 -41.437 -8.190 1.0031.75C
ATOM7597CB PHEG136 -9.141 -40.416 -9.284 1.0031.33C
ATOM7598CG PHE G136 -8.304-40.514-10.530 1.0029.78C
ATOM7599CDl PHEG136 -7.031 -39.956-10.570 1.0025.27C
ATOM7600CEl PHE G136 -6.272-40.034-11.694 1.00 23.75C
ATOM7601CZ PHE G136 -6.756-40.684-12.818 1.0027.64C
ATOM7602CE2PHEG136 -8.024-41.246-12.802 1.00 25.88C
ATOM7603CD2 PHE G136 -8.792-41.143-11.663 1.0027.13C
ATOM7604C PHE G136 -8.979 -42.835 -8.736 1.00 33.74C
ATOM7605O PHE G136-10.129 -43.307 -8.835 1.00 34.09O
[0414]ATOM7606NLYS G137 -7.893 -43.513 -9.119 1.00 35.40NATOM7607CALYS G137 -8.051 -44.884 -9.599 1.00 36.85C
ATOM7608CBLYS G137 -6.755 -45.499-10.135 1.0035.80C
ATOM7609CGLYS G137 -6.192-44.834-11.375 1.0036.95C
ATOM7610CDLYS G137 -7.221 -44.747-12.518 1.00 37.51C ATOM7611CELYS G137 -6.535-44.380-13.814 1.00 37.75C
ATOM7612NZLYS G137 -7.439-44.526-14.986 1.00 38.81N
ATOM7613CLYS G137 -8.670 -45.755 -8.508 1.00 38.40C
ATOM7614OLYS G137 -8.605 -45.459 -7.298 1.0038.98O
ATOM7615NTHRG138 -9.259 -46.849 -8.960 1.00 39.82N
ATOM7616CATHRG138-10.041 -47.685 -8.119 1.00 40.81C
ATOM7617CBTHRG138-11.518-47.519 -8.520 1.00 41.26C
ATOM7618OGl THRG138 -12.260 -47.066 -7.390 1.0042.20O
ATOM7619CG2THRG 138-12.123 -48.792 -9.142 1.0040.00C
ATOM7620CTHRG138 -9.543-49.116 -8.295 1.00 41.97C
ATOM7621OTHRG138 -9.028 -49.482 -9.369 1.00 42.45O
ATOM7622NGLY G139 -9.663 -49.899 -7.218 1.00 42.79N
ATOM7623CAGLYG139 -9.488 -51.346 -7.265 1.00 43.29C
ATOM7624CGLYG139 -8.138-51.768 -7.779 1.0043.67C
ATOM7625OGLYG 139 -7.122 -51.497 -7.142 1.00 44.13O
ATOM7626NALAG140 -8.140 -52.407 -8.948 1.0043.93N
ATOM7627CAALAG140 -6.954-53.069 -9.486 1.00 43.94C
ATOM7628CBALAG140 -7.341 -54.179-10.455 1.00 44.25C
ATOM7629CALAG140 -5.940 -52.132-10.132 1.0043.76C
ATOM7630OALAG140 -4.736 -52.370 -9.993 1.0044.42O
ATOM7631NGLU G141 -6.379 -51.089-10.848 1.0042.65N
ATOM7632CAGLU G141 -5.367 -50.167-11.361 1.00 41.63C
ATOM7633CBGLUG141 -5.723 -49.530-12.710 1.0041.56C
ATOM7634CGGLUG 141 -6.839-48.570-12.752 1.00 42.08C
ATOM7635CDGLUG141 -7.219-48.210-14.196 1.00 42.09C
ATOM7636OEl GLU G141 -8.437-48.124-14.508 1.0044.75O
ATOM7637OE2GLUG141 -6.304-48.010-15.018 1.0041.60O
ATOM7638CGLU G141 -4.845 -49.176-10.318 1.0040.66C
ATOM7639OGLUG141 -3.791 -48.573 -10.515 1.0040.27O
ATOM7640NARG G142 -5.577 -49.064 -9.206 1.00 39.74N
ATOM7641CAARGG142 -5.200-48.273 -8.054 1.00 39.08C
ATOM7642CBARG G142 -6.416 -48.036 -7.171 1.00 39.28C
ATOM7643CGARGG142 -6.107-47.191 -5.959 1.00 40.91C
ATOM7644CDARG G142 -7.203 -47.246 -4.896 1.00 43.77C
ATOM7645NEARG G142 -6.553 -47.383 -3.601 1.0045.39N
ATOM7646CZARG G142 -6.035 -46.391 -2.881 1.0044.66C
ATOM7647NHl ARG G142 -5.432-46.666 -1.731 1.0043.23N
ATOM7648NH2ARGG142 -6.123 -45.141 -3.289 1.00 44.55N
ATOM7649CARG G142 -4.076 -48.927 -7.239 1.00 38.80C
[0415]ATOM 7650O ARG G 142-3.087 -48.259 -6.8681.00 38.98OATOM 7651N LYS G143-4.239 -50.224 -6.9551.00 37.56N
ATOM 7652CA LYS G143-3.208-51.048 -6.3211.00 36.57C
ATOM 7653CB LYS G 143-3.719-52.476 -6.1161.00 37.19C
ATOM 7654CG LYS G143-4.757 -52.635 -4.9951.00 39.41C
ATOM7655CD LYS G 143-4.545 -53.976 -4.2641.0042.37C
ATOM7656CE LYS G143-5.725 -54.337 -3.3911.00 43.14C
ATOM7657NZ LYS G143-5.310-55.401 -2.4331.00 43.52N
ATOM7658C LYS G143-1.932-51.088 -7.1671.00 35.17C
ATOM7659O LYS G143-0.819-51.151 -6.6551.00 34.86O
ATOM7660N GLU G144-2.127-51.047 -8.4671.00 33.19N
ATOM7661CA GLU G144 -1.068 -51.057 -9.4291.00 32.66C
ATOM7662CB GLU G144-1.688 -51.384-10.7811.00 32.78C
ATOM7663CG GLU G144 -0.711 -51.517-11.8901.00 37.27C
ATOM7664CD GLU G144 -1.382 -51.743 -13.2281.0042.57C
ATOM7665OEl GLUG144-1.037-50.963-14.1561.00 44.38O
ATOM7666OE2GLUG144-2.243 -52.674-13.3241.00 42.23O
ATOM7667C GLU G 144-0.311 -49.718 -9.4931.0031.21C
ATOM7668O GLUG 1440.908 -49.705 -9.6431.0031.77O
ATOM7669N ALAG 145-1.038-48.605 -9.4131.0029.58N
ATOM7670CA ALAG145-0.425 -47.282 -9.3021.0029.21C
ATOM7671CB ALAG145-1.424 -46.186 -9.5881.0027.50C
ATOM7672C ALAG1450.280 -47.069 -7.9301.00 28.46C
ATOM7673O ALAG1451.351 -46.493 -7.9111.0027.92O
ATOM7674N ALAG146-0.310-47.533 -6.8121.00 28.85N
ATOM7675CA ALA G1460.393 -47.514 -5.4781.00 30.12C
ATOM7676CB ALAG146-0.511-48.013 -4.3561.0029.70C
ATOM7677C ALAG1461.703 -48.316 -5.5071.00 30.55C
ATOM7678O ALAG1462.735 -47.910 -4.9401.00 30.99O
ATOM7679N GLU G1471.648 -49.432 -6.2211.0031.28N
ATOM7680CA GLUG1472.789 -50.292 -6.5171.00 33.34C
ATOM7681CB GLU G1472.327 -51.391 -7.4771.00 33.79C
ATOM7682CG GLU G1472.502 -52.834 -7.0171.00 37.73C
ATOM7683CD GLUG 1471.565 -53.813 -7.8021.00 37.86C
ATOM7684OEl GLUG1470.769-54.515 -7.1211.0042.81O
ATOM7685OE2 GLUG1471.610-53.850 -9.0781.0041.30O
ATOM7686C GLUG 1473.927-49.515 -7.1751.00 32.05C
ATOM7687O GLUG1475.063 -49.471 -6.6381.0031.22O
ATOM7688N SERG1483.631-48.916 -8.3411.00 30.79N
ATOM7689CA SERG1484.637 -48.178 -9.0891.0029.41C
ATOM7690CB SERG1484.097 -47.772-10.4441.00 30.63C
ATOM7691OG SERG1483.516-48.886-11.1571.00 29.94O
ATOM7692C SERG1485.197-46.968 -8.3081.00 29.26C
ATOM7693O SERG1486.349-46.582 -8.4951.00 27.60O
[0416]ATOM 7694N THRG1494.372 -46.387-7.4291.00 29.41NATOM 7695CA THRG 1494.743 -45.219-6.605 1.00 29.10C
ATOM 7696CB THRG1493.481 -44.676-5.8881.00 29.68C
ATOM 7697OGl THRG1492.450 -44.470-6.8531.00 29.12O
ATOM 7698CG2THRG1493.774 -43.416-5.1291.0028.43C
ATOM 7699C THR G1495.782 -45.571-5.5391.00 28.67C
ATOM 7700O THRG1496.809 -44.868-5.3701.00 29.91O
ATOM 7701N METG1505.456 -46.624-4.7871.00 27.80N ATOM7702CA METG1506.312-47.256-3.825 1.0027.21C
ATOM7703CB METG1505.613 -48.528-3.315 1.00 28.01C
ATOM 7704CG METG 1506.353 -49.340-2.248 1.0026.60C
ATOM 7705SD METG1506.815-48.341-0.796 1.0025.69S
ATOM 7706CE METG1505.470-48.733 0.310 1.00 21.14C
ATOM7707C METG1507.667 -47.560-4.4721.0027.47C
ATOM7708O METG1508.746 -47.106-3.9841.0024.87O
ATOM7709N THRG1517.616-48.291-5.5871.0026.23N
ATOM7710CA THRG1518.841 -48.607-6.3341.00 26.72C
ATOM7711CB THRG1518.579 -49.542-7.5231.00 26.71C
ATOM7712OGl THRG1518.224 -50.832-7.0131.00 29.69O
ATOM7713CG2 THRG1519.832 -49.707-8.3821.0027.21C
ATOM7714C THRG1519.656 -47.377-6.7391.00 26.32C
ATOM7715O THRG15110.857-47.331-6.4461.00 28.04O
ATOM7716N ALAG1529.030-46.375-7.3741.00 24.33N
ATOM7717CA ALAG1529.777 -45.192-7.7631.00 23.67C
ATOM7718CB ALAG1528.931 -44.320-8.6421.00 23.35C
ATOM7719C ALA G15210.360-44.399-6.5631.00 22.39C
ATOM7720O ALAG15211.506 -43.932-6.6001.00 21.73O
ATOM7721N TYRG1539.540 -44.209-5.5221.00 22.81N
ATOM7722CA TYRG1539.965 -43.485-4.2841.00 22.31C
ATOM7723CB TYRG1538.797 -43.267-3.3001.0021.84C
ATOM7724CG TYRG 1537.851 -42.123-3.6101.0020.02C
ATOM7725CDl TYRG1538.174-41.173-4.5541.0021.18C
ATOM7726CEl TYRG1537.274 -40.146-4.8491.0023.79C
ATOM7727CZ TYRG1536.092 -40.038-4.1351.0020.82C
ATOM7728OH TYRG1535.256-38.997-4.419 1.00 22.78O
ATOM7729CE2 TYRG1535.773 -40.942-3.1561.0016.54C
ATOM7730CD2TYRG1536.643-41.991-2.9201.00 19.84C
ATOM7731C TYRG15311.070-44.164-3.5011.0023.38C
ATOM 7732O TYRG15311.964-43.481-2.9281.00 22.90O
ATOM 7733N LYS G15410.956-45.491-3.4151.00 23.95N
ATOM 7734CA LYS G15411.958-46.375-2.8161.00 26.56C
ATOM 7735CB LYS G15411.504-47.832-2.9371.0027.09C
ATOM 7736CG LYS G15411.759-48.825-1.7631.00 30.43C
ATOM 7737CD LYS G15410.600 -49.944-1.7371.00 30.10C
[0417]ATOM7782N LEUG16119.696-41.146-0.1191.0023.23N
ATOM7783CA LEU G16120.350-41.5171.1041.0023.87C
ATOM7784CB LEU G16119.777-42.7991.6061.0023.22C
ATOM7785CG LEUG16119.816-43.0583.0721.0024.91C
ATOM7786CDl LEUG16120.756-42.0723.9381.0025.62C
ATOM7787CD2LEUG16120.281 -44.4853.0871.00 25.40C·ATOM7788C LEUG16121.811 -41.7440.8991.00 24.67C
ATOM7789O LEUG16122.606-41.2%1.7151.00 27.31O
ATOM7790N ALAG16222.181 -42.448-0.1611.00 24.54N
ATOM7791CA ALAG 16223.591 -42.714-0.4631.00 24.88C
ATOM7792CB ALAG16223.739 -43.693-1.5691.0024.37C
ATOM7793C ALAG16224.295 -41.444-0.8271.0025.96C
ATOM7794O ALAG16225.375-41.154-0.2771.0026.29O
ATOM7795N ASPG16323.676 -40.642-1.6961.0025.73N
ATOM7796CA ASPG16324.404 -39.523-2.2791.00 26.49C
ATOM7797CB ASPG16324.499-39.724-3.8081.0027.40C
ATOM7798CG ASPG16325.567-40.757-4.1971.00 29.23C
ATOM7799ODl ASPG16326.135-41.469-3.3291.00 32.84O
ATOM7800OD2ASPG16325.836 -40.864-5.3901.00 33.10O
ATOM7801C ASPG16324.077-38.053-1.9521.0025.86C
ATOM7802O ASPG16324.861 -37.186-2.3181.00 24.76O
ATOM7803N LEUG16422.935 -37.758-1.3251.00 24.83N
ATOM7804CA LEU G16422.533 -36.359-1.1621.00 24.82C
ATOM7805CB LEU G16421.113-36.070-1.7131.00 24.46C
ATOM7806CG LEU G16420.785 -36.179-3.1881.00 23.67C
ATOM7807CDI LEU G16419.348 -35.758-3.3681.0022.53C
ATOM7808CD2 LEU G16421.772 -35.385-4.1221.0016.57C
ATOM7809C LEUG16422.517-36.1220.3101.0025.11C
ATOM7810O LEU G16422.262 -37.0391.0491.0024.96O
ATOM7811N ALAG16522.813 -34.8930.7161.0026.12N
ATOM7812CA ALAG16522.829 -34.4902.1201.0025.91C
ATOM7813CB ALAG16523.403 -33.0602.2761.0026.45C
ATOM7814C ALAG16521.406 -34.5672.6451.0025.41C
ATOM7815O ALAG16520.444-34.5051.8501.0024.29O
ATOM7816N PRO G16621.279-34.7683.9641.0024.80N
ATOM7817CA PRO G16620.002-34.9194.6511.0024.58C
ATOM7818CB PRO G16620.412-35.3056.0801.0024.92C
ATOM7819CG PRO G16621.794-34.6516.2481.0025.10C
ATOM7820CD PRO G16622.429 -34.8804.8951.0025.11C
Α1ΌΜ7821C PROG 16619.182 -33.6344.5731.00 24.58C
ATOM7822O PROG 16617.951 -33.6714.6761.00 24.52O
ATOM7823N THRG 16719.881 -32.5284.2991.00 24.24N
ATOM7824CA THRG167 19.364-31.1834.226 1.0023.70C
ATOM7825CB THRG16720.467 -30.1664.6851.0024.51C
[0419]ATOM7870CDl LEU G17215.600 -30.820 3.3651.0018.76C
ATOM7871CD2LEUG17214.811 -33.020 4.3381.0011.97C
ATOM7872C LEU G17212.188 -33.578 0.9331.00 20.04C
ATOM7873O LEU G17211.205 -33.964 1.5741.0019.30O
ATOM7874N GLYG17312.092-33.141-0.3271.00 20.56N
ATOM7875CA GLYG17310.825 -33.174-1.1011.00 22.37 C
ATOM7876C GLYG17310.372-34.588-1.2451.00 20.99C ATOM7877O GLYG1739.231 -34.887-1.0011.00 25.35O
ATOM7878N LEU G17411.297 -35.462-1.6051.0021.22N
ATOM7879CA LEU G17411.088-36.916-1.6581.00 20.55 C
ATOM7880CB LEU G17412.376 -37.668-2.1271.00 20.37 C
ATOM7881CG LEU G17412.349-39.172 -2.4431.0020.32 C
ATOM7882CDl LEU G17412.558 -39.974-1.1851.0016.54C
ATOM7883CD2LEUG17410.955 -39.635-3.1601.00 19.21C
ATOM7884C LEU G17410.492-37.509-0.3881.00 20.21C
ATOM7885O LEU G1749.425 -38.228-0.4571.00 19.39O
ATOM7886N ALA G17511.157 -37.258 0.7411.0017.25N
ATOM7887CA ALAG 17510.631-37.676 2.0651.0017.14 C
ATOM7888CB ALAG17511.519-37.157 3.2151.0017.95 C
ATOM7889C ALAG1759.226 -37.1782.3471.0015.92C
ATOM7890O ALAG1758.468 -37.825 3.0131.0016.97O
ATOM7891N LEU G1768.934 -35.961 1.9411.00 15.73N
ATOM7892CA LEU G1767.673 -35.388 2.2181.00 16.69 C
ATOM7893CB LEU G1767.724 -33.897 1.8591.0016.10C
ATOM7894CG LEUG 1766.475 -33.017 1.9281.00 10.42 C
ATOM7895CDl LEU G1765.906 -32.814 3.2711.00 13.63C
ATOM7896CD2LEUG1766.697 -31.762 1.2301.00 8.33 C
ATOM7897C LEUG1766.572-36.124 1.3971.0018.42C
ATOM7898O LEU G1765.540 -36.500 1.9471.00 20.34O
ATOM7899N ASN G1776.829 -36.305 0.1181.0019.08N
ATOM7900CA ASNG1775.845 -36.871-0.8201.00 20.67 C
ATOM7901CB ASNG1776.266 -36.615-2.2891.00 18.76C
ATOM7902CG ASNG1775.854-35.243-2.7651.0018.32 C
ATOM7903ODl ASN G1775.326 -34.508-1.9971.0021.96O
ATOM7904ND2ASNG1776.083 -34.897-4.0441.00 20.37N
ATOM7905C ASN G1775.671 -38.316-0.4981.00 21.43C
ATOM7906O ASN G1774.567 -38.758-0.4061.00 24.61O
ATOM7907N PHE G1786.771 -39.044-0.3061.00 23.78N
ATOM7908CA PHEG1786.805 -40.416 0.2651.00 23.82 C
ATOM7909CB PHEG1788.269 -40.878 0.4861.00 25.12C
ATOM7910CG PHEG1788.502-42.365 0.2921.0025.06 C
ATOM7911CDl PHEG1787.440-43.2480.0181.00 28.61C
ATOM7912CEl PHE G1787.660 -44.617-0.1511.0027.58C
ATOM7913CZ PHE G1788.947-45.124-0.0261.00 27.02C
[0421]ATOM7914CE2PHEG17810.011 -44.2450.2891.00 22.52CATOM7915CD2 PHE G1789.765 -42.8870.4391.00 23.05C
ATOM7916C PHEG1785.989 -40.5731.5561.0024.61C
ATOM7917O PHEG 1785.119-41.4571.6281.00 24.70O
ATOM7918N SERG1796.212 -39.7252.5701.00 24.09N
ATOM7919CA SERG 1795.244-39.7193.7511.0024.34C ATOM7920CB SERG1795.608 -38.6774.7931.0024.40C
ATOM7921OG SERG 1795.486-37.3714.2631.0027.71O
ATOM7922C SERG1793.735 -39.5463.3921.00 24.00C
ATOM7923O SERG1792.868 -40.2403.9401.00 23.70O
ATOM7924N VALG 1803.455 -38.6082.4901.00 23.32N
ATOM7925CA VALG1802.113-38.2712.0441.0023.47C
ATOM7926CB VALG1802.123 -36.9421.1741.0024.29C
ATOM7927CGl VALG1800.855 -36.7630.3511.0021.87C
ATOM7928CG2VALG1802.385 -35.6802.0661.00 22.85C
ATOM7929C VALG1801.448 -39.4491.3511.0023.12C
ATOM7930O VALG1800.277 -39.6421.5391.0024.31O
ATOM7931N PHEG1812.211 -40.2110.5671.00 23.90N
ATOM7932CA PHEG1811.858-41.5330.0021.0024.37C
ATOM7933CB PHEG1813.057 -42.118-0.7881.00 23.54C
ATOM7934CG PHEG1812.812-43.509-1.3501.0024.84C
ATOM7935CDl PIIEG1811.746 -43.746-2.2321.00 23.90C
ATOM7936CEl PHEG1811.492 -45.032-2.7351.00 23.16C
ATOM7937CZ PHE G1812.300-46.079-2.3811.00 24.41C
ATOM7938CE2PHEG1813.382 -45.862-1.4991.0026.10C
ATOM7939CD2PHEG1813.632 -44.583-0.9991.0023.65C
ATOM7940C PHEG1811.356 -42.5471.0471.0025.55C
ATOM7941O PHEG1810.274-43.1880.8891.00 24.37O
ATOM7942N TYRG1822.134-42.6882.1141.00 25.46N
ATOM7943CA TYRG1821.772-43.5623.232 1.00 26.88C
ATOM7944CB TYRG1822.914 -43.6204.2731.00 26.90C
ATOM7945CG TYRG1823.975 -44.6473.905 1.0027.76C
ATOM7946CDl TYRG1823.714-46.0214.0201.0027.11C
ATOM7947CEl TYRG1824.666-46.9683.6701.00 24.60C
ATOM7948CZ TYR G1825.882 -46.5603.1881.0025.89C
ATOM7949OH TYRG1826.804-47.517 2.836 1.0026.58O
ATOM7950CE2TYRG1826.175 -45.2113.0561.0025.17C
ATOM7951CD2TYRG1825.224-44.2573.4141.0025.84C
ATOM7952C TYRG1820.478 -43.1253.9011.0027.54C
ATOM7953O TYRG182-0.419-43.9334.1381.00 27.68O
ATOM7954N TYRG1830.393 -41.8444.2031.00 29.14N
ATOM7955CA TYRG183-0.796 -41.2514.8121.00 30.79C
ATOM7956CB TYRG183-0.531-39.7805.2001.0031.39C
ATOM7957CG TYRG183-1.587 -39.2406.1521.0033.07C
[0422]ATOM7958CDl TYRG183 -1.479 -39.441 7.535 1.00 32.48CATOM7959CEl TYRG183 -2.477 -38.960 8.413 1.00 33.23C
ATOM7960CZ TYRG183 -3.590 -38.292 7.898 1.00 34.68C
ATOM7961OH TYRG183 -4.558 -37.814 8.761 1.00 36.85 O
ATOM7962CE2TYRG183 -3.738 -38.096 6.525 1.00 35.32C
ATOM7963CD2TYRG183 -2.736-38.576 5.661 1.00 36.19C·ATOM7964C TYRG183 -2.077-41.342 3.940 1.00 31.28C
ATOM7965O TYR G183 -3.086-41.934 4.375 1.00 30.19O
ATOM7966N GLUG184 -2.051 -40.749 2.740 1.0031.56N
ATOM7967CA GLU G184 -3.303 -40.692 1.983 1.00 32.53 C
ATOM7968CB GLU G184 -3.726 -39.273 1.511 1.00 33.27C
ATOM7969CG GLU G184 -3.019-38.546 0.352 1.00 34.67 C
ATOM7970CD GLU G184 -2.928 -37.006 0.603 1.00 34.57 C
ATOM7971OEl GLUG184 -3.072 -36.588 1.784 1.00 37.44O
ATOM7972OE2GLUG184 -2.695 -36.210 -0.354 1.00 35.47O
ATOM7973C GLU G184 -3.623-41.839 1.024 1.00 32.12C
ATOM7974O GLUG 184 -4.786-42.144 0.845 1.00 32.81O
ATOM7975N ILE G185 -2.614-42.496 0.464 1.0031.78N
ATOM7976CA ILEG 185 -2.829 -43.668 -0.384 1.0031.29C
ATOM7977CB ILE G185 -1.845 -43.704 -1.590 1.0031.29C
ATOM7978CGl ILE G 185 -1.867 -42.378 -2.374 1.00 28.62C
ATOM7979CDl ILE G185 -3.188 -41.994 -2.956 1.00 30.50C
ATOM7980CG2ILEG185 -2.113-Φ4.953 -2.494 1.00 30.64C
ATOM7981C ILE G185 -2.793 -45.022 0.377 1.0031.92C
ATOM7982O ILE G185 -3.651 -45.879 0.170 1.00 30.35O
ATOM7983N LEU G186 -1.808 -45.204 1.256 1.00 32.43N
ATOM7984CA LEU G186 -1.650-46.470 1.943 1.00 32.61C
ATOM7985CB LEU G186 -0.176 -46.758 2.231 1.00 32.58C
ATOM7986CG LEU G186 0.531 -47.770 1.305 1.00 33.43C
ATOM7987CDl LEU G186 0.025 -47.739 -0.133 1.00 30.86C
ATOM7988CD2LEUG186 2.028 -47.596 1.346 1.0031.18C
ATOM7989C LEU G186 -2.480 -46.526 3.203 1.0033.28C
ATOM7990O LEU G186 -2.735 -47.604 3.735 1.00 33.46O
ATOM7991N ASN G187 -2.917-45.365 3.666 1.0033.79N
ATOM7992CA ASNG187 -3.689 -45.269 4.906 1.00 35.10C
ATOM7993CB ASN G187 -5.011 -46.053 4.745 1.00 35.66C
ATOM7994CG ASNG187 -6.039 -45.745 5.828 1.00 39.77C
ATOM7995ODl ASN G187 -5.940 -44.739 6.538 1.0043.78O
ATOM7996ND2ASNG187 -7.041 -46.632 5.966 1.0042.58N
ATOM7997C ASNG 187 -2.883 -45.671 6.185 1.00 34.30C
ATOM7998O ASN G187 -3.443 -46.202 7.146 1.00 34.56O
ATOM7999N SERG 188 -1.572 -45.412 6.197 1.00 33.83N
ATOM8000CA SERG188 -0.752 -45.705 7.390 1.00 33.22C
ATOM8001CB SERG188 0.254-46.833 7.176 1.00 32.94C
[0423]ATOM8002OG SERG1880.819-46.7625.901 1.00 35.64OATOM8003C SERG188-0.074 -44.4837.953 1.00 32.40C
ATOM8004O SERG1881.035-44.1677.559 1.00 32.61O
ATOM8005N PRO G189-0.767 -43.7878.869 1.00 32.20N
ATOM8006CA PRO G189-0.325 -42.5499.481 1.00 32.03C
ATOM8007CB PRO G189-1.599-42.05710.196 1.00 32.12C
ATOM8008CG PRO G189-2.313-43.30310.560 1.0031.81C
ATOM8009CD PRO G189-2.115-44.1669.356 1.0031.91C
ATOM8010C PRO G1890.861 -42.70610.438 1.0031.92C
ATOM8011O PRO G1891.627 -41.75310.584 1.00 32.64O
ATOM8012N ASPG1901.044-43.88711.031 1.0031.55N
ATOM8013CA ASPG1902.208 -44.15111.876 1.00 32.88C
ATOM8014CB ASPG1902.103 -45.49112.621 1.00 33.30C
ATOM8015CG ASPG1901.124-45.45613.790 1.00 37.09C
ATOM8016ODl ASP G1900.937 -44.39214.431 1.00 41.31O
ATOM8017OD2ASPG1900.533 -46.52314.080 1.00 42.01O
ATOM8018C ASPG1903.492-44.15411.053 1.00 32.27C
ATOM8019O ASPG1904.514-43.53611.432 1.0031.10O
ATOM8020N ARGG1913.424-44.8819.941 1.0031.99N
ATOM8021CA ARGG1914.528 -44.9358.979 1.0031.50C
ATOM8022CB ARGG1914.370 -46.0967.981 1.0032.31C
ATOM8023CG ARGG1915.526 -46.1636.960 1.00 35.18C
ATOM8024CD ARGG1916.831 -46.5627.596 1.00 36.94C
ATOM8025NE ARGG1917.851 -46.8996.606 1.0040.98N
ATOM8026CZ ARGG1919.054 -46.3286.537 1.0045.59C
ATOM8027NHl ARGG1919.414-45.3777.419 1.0047.85N
ATOM8028NH2ARGG1919.915-46.7085.589 1.0048.04N
ATOM8029C ARGG1914.740 -43.5898.270 1.00 29.99C
ATOM8030O ARGG1915.883 -43.1048.217 1.0029.48O
ATOM8031N ALAG1923.666 -42.9687.771 1.00 27.88N
ATOM8032CA ALAG 1923.798 -41.5947.257 1.0027.82C
ATOM8033CB ALAG1922.460-41.0046.965 1.0026.39C
ATOM8034C ALAG1924.591 -40.6868.232 1.0027.91C
ATOM8035O ALAG1925.502 -39.9877.823 1.0028.66O
ATOM8036N CYS G1934.228 -40.7099.508 1.0028.41N
ATOM8037CA CYS G1934.850-39.86710.527 1.0028.89C
ATOM8038CB CYS G1934.071 -39.90811.844 1.0028.33C
ATOM8039SG CYS G1932.544-39.01911.923 1.0029.62S
ATOM8040C CYS G1936.273 -40.26910.823 1.00 28.92C
ATOM8041O CYS G1937.125 -39.39810.849 1.00 30.92O
ATOM8042N ASN G1946.529-41.55211.101 1.00 29.09N
ATOM8043CA ASN G1947.916 -42.08311.224 1.0029.99C
ATOM8044CB ASN G1947.933 -43.62111.279 1.00 30.76C
ATOM8045CG ASNG1947.273 -44.16512.528 1.00 34.47C
[0424]ATOM8046ODl ASN G1947.148 -45.38912.7021.00 38.70OATOM8047ND2ASNG1946.817 -43.26213.3991.00 37.02N
ATOM8048C ASNG1948.877-41.64510.1121.00 28.83C
ATOM8049O ASN G19410.004-41.19010.3861.00 28.27O
ATOM8050N LEUG 1958.411 -41.7718.8711.0026.22N
ATOM8051CA LEU G1959.214-41.4367.6731.00 25.39C
ATOM8052CB LEU G1958.452-41.8516.4041.00 24.55C
ATOM8053CG LEU G1959.198-42.2635.1431.0026.28C
ATOM8054CDl LEU G1958.160-42.9914.2351.00 24.67C
ATOM8055CD2LEUG1959.778 -41.0794.4691.00 22.11C
ATOM8056C LEU G1959.531-39.9577.5741.0023.79C
ATOM8057O LEU G19510.667 -39.5717.2721.0024.03O
ATOM8058N ALAG1968.505 -39.1317.7901.0022.77N
ATOM8059CA ALAG1968.681 -37.6867.786 1.0022.04C
ATOM8060CB ALAG1967.341 -36.9537.7831.0020.92C
ATOM8061C ALAG 1969.544-37.1738.9481.0020.93C
ATOM8062O ALA G19610.207 -36.2058.7811.0020.71O
ATOM8063N LYS G1979.452-37.79110.1131.0021.91N
ATOM8064CA LYS G19710.079 -37.29211.3571.00 23.00C
ATOM8065CB LYS G1979.355 -37.87712.6051.0023.21C
ATOM8066CG LYS G1979.991 -37.56114.0131.00 23.67C
ATOM8067CD LYS G19710.212 -36.06814.2671.00 24.11C
ATOM8068CE LYS G19710.727 -35.74915.7341.0024.18C
ATOM8069NZ LYS G19711.597 -36.80516.2681.0020.93N
ATOM8070C LYS G19711.566-37.64111.2981.0023.17C
ATOM8071O LYS G19712.446 -36.81111.6081.0022.45O
ATOM8072N GLN G19811.821 -38.87010.8541.0023.61N
ATOM8073CA GLNG19813.152 -39.304 10.479 1.0025.24C
ATOM8074CB GLN G19813.186 -40.7419.969 1.00 25.74C
ATOM8075CG GLNG19814.554-41.054 9.354 1.00 29.85C
ATOM8076CD GLNG19814.846-42.499 9.288 1.00 36.42C
ATOM8077ORI GLN G19814.254-43.29310.0191.0041.12O
ATOM8078NE2GLNG19815.759-42.8778.3981.00 39.28N
ATOM8079C GLNG19813.853 -38.4009.4871.0024.97C
ATOM8080O GLN G19814.991 -38.0339.7241.00 26.84O
ATOM8081N ALAG19913.208 -38.0338.3861.0024.99N
ATOM8082CA ALAG19913.832 -37.1477.403 1.0024.15C
ATOM8083CB ALAG19912.963 -36.9926.185 1.0024.43C
ATOM8084C ALAG19914.060 -35.7978.0471.00 24.52C
ATOM8085O ALAG 19915.118-35.1687.9041.0023.95O
ATOM8086N PHE G 20013.046 -35.3478.7761.0024.27N
ATOM8087CA PHE G 20013.168 -34.0979.4721.00 23.41C
ATOM8088CB PHE G 20011.839-33.80110.1301.00 23.33C
ATOM8089CG PHE G 20011.806 -32.48510.771 1.0022.17C
[0425]ATOM8090CDl PHE G 20011.417-31.36510.0411.0018.58CATOM8091CEl PHE G 20011.415-30.13510.6111.0021.09C
ATOM8092CZ PHE G 20011.801-29.99111.9581.0017.20C
ATOM8093CE2PHEG20012.193 -31.07712.6661.0016.90C
ATOM8094CD2PHEG20012.208 -32.33912.0841.0019.38C
ATOM8095C PHE G 20014.330-34.04210.4931.0022.75C
ATOM8096O PHE G 20015.114-33.09810.5021.0023.70O
ATOM8097N ASP G 20114.437 -35.05411.3481.0023.61N ATOM8098CA ASP G 20115.534 -35.18712.332 1.00 23.14C
ATOM8099CB ASP G 20115.299 -36.43913.192 1.0022.42C
ATOM8100CG ASP G 20114.317-36.22514.235 1.00 23.17C
ATOM8101ODl ASP G 20113.727-35.14714.2551.00 28.16O
ATOM8102OD2ASPG20114.129-37.11515.0891.0025.41O
ATOM8103C ASP G 20116.937 -35.31611.6921.00 23.03C
ATOM8104O ASP G 20117.937 -34.75912.2341.0021.89O
ATOM8105N GLU G 20217.039-36.11410.620 1.0021.33N
ATOM8106CA GLU G 20218.312-36.178 9.886 1.0023.27C
ATOM8107CB GLU G 20218.328 -37.172 8.714 1.0022.99C
ATOM8108CG GLU G 20218.430-38.600 9.068 1.0022.13C
ATOM8109CD GLU G 20217.788-39.480 8.006 1.0025.08C
ATOM8110OEl GLU G 20217.785 -40.7048.2061.0023.76O
ATOM8111OE2GLUG20217.319-38.9626.9481.00 24.10O
ATOM . 8112C GLU G 20218.753-34.8139.3551.0024.40C
ATOM8113O GLU G 20219.912 -34.4679.5061.00 26.35O
ATOM8114N ALAG 20317.855-34.0278.7511.0024.50N
ATOM8115CA ALA G 20318.235-32.6638.348 1.0023.71C
ATOM8116CB ALA G 20317.226 -32.0567.498 1.0023.67C
ATOM8117C ALAG 20318.556-31.7239.5161.00 24.84C
ATOM8118O ALAG 20319.402-30.8449.3451.00 23.74O
ATOM8119N ILE G 20417.847 -31.86710.6491.00 25.45N
ATOM8120CA ILE G 20418.073 -31.04111.8121.00 26.99C
ATOM8121CB ILE G 20417.034 -31.27612.9751.0026.90C
ATOM8122CGl ILE G 20415.692 -30.60312.7171.0024.28C
ATOM8123CDl ILE G 20415.750-29.10212.4991.00 20.88C
ATOM8124CG2ILE G 20417.578 -30.74214.2981.0026.86C
ATOM8125C ILE G 20419.522 -31.22012.3071.0027.98C
ATOM8126O ILE G 20420.191 -30.24212.5611.0029.86O
ATOM8127N SER G 20519.994 -32.46312.3941.0029.53N
ATOM8128CA SER G 20521.397 -32.77712.657 1.00 30.61C
ATOM8129 CB SER G 20521.683 -34.28512.604 1.0030.46C
ATOM8130 OG SER G 20521.797 -34.77311.261 1.0031.88O
ATOM8131C SER G 20522.407 -32.02311.7831.0031.17C
ATOM8132 O SER G 20523.541 -31.82012.2061.00 32.24O
ATOM8133N GLU G 20622.003 -31.56110.602 1.00 30.78N
[0426]ATOM8134CA GLU G 206 22.957 -30.9209.6891.0029.67CATOM8135CB GLU G 20623.179 -31.7558.4251.00 28.98C
ATOM8136CG GLU G 206 23.697 -33.1378.7041.0029.65C
ATOM8137CD GLU G 206 24.431 -33.7557.5211.0029.74C
ATOM8138OEl GLU G 20624.575 -33.0886.4621.00 30.32O
ATOM8139OE2 GLU G 20624.874-34.9107.6691.00 30.67O
ATOM8140C GLU G 20622.633 -29.4939.3111.0029.41C ATOM8141O GLU G 20623.459 -28.8658.6581.00 29.43O
ATOM8142N LEU G 20721.467-28.9759.7261.00 29.27N
ATOM8143CA LEU G 20721.003 -27.6439.2981.00 30.18C
ATOM8144CB LEU G 20719.638 -27.3679.8921.00 29.79C
ATOM8145CG LEU G 20718.769 -26.2499.3141.00 30.81C
ATOM8146CDl LEU G 20718.185 -26.6517.9261.00 30.09C
ATOM8147CD2LEUG20717.661 -25.94110.2971.00 28.76C
ATOM8148C LEU G 20721.976-26.4639.6161.0031.96C
ATOM8149O LEU G 20722.022 -25.4728.9021.00 32.48O
ATOM8150N ASP G 20822.754 -26.57510.6791.00 33.81N
ATOM8151CA ASP G 20823.624 -25.46011.1091.00 35.66C
ATOM8152CB ASP G 20823.741 -25.44712.6461.00 36.07C
ATOM8153CG ASP G 20824.267-26.75713.2211.00 39.84C
ATOM8154ODl ASP G 20823.797 -27.86412.8231.00 44.03O
ATOM8155OD2ASPG20825.142-26.68614.1141.0043.67O
ATOM8156C ASP G 20825.011 -25.43510.4451.00 35.96C
ATOM8157O ASP G 20825.863 -24.61010.7981.00 36.80O
ATOM8158N THR G 20925.236-26.3369.4911.00 36.43N
ATOM8159CA THR G 20926.503 -26.4228.7581.00 36.40C
ATOM8160CB THRG 20926.950 -27.9018.4811.00 36.47C
ATOM8161OGl THR G 20926.059 -28.5477.5451.00 37.67O
ATOM8162CG2THRG20927.038 -28.7149.7611.00 35.19C
ATOM8163C THR G 20926.431 -25.6427.4411.00 36.64C
ATOM8164O THR G 20927.447-25.3856.8021.00 37.04O
ATOM8165N LEU G 21025.213 -25.2577.0771.00 36.89N
ATOM8166CA LEU G 21024.853 -24.7195.7811.00 36.62C
ATOM8167CB LEU G 21023.359 -25.0155.5031.00 35.72C
ATOM8168CG LEU G 21022.840 -26.4375.3061.00 34.61C
ATOM8169CDl LEU G 21021.343 -26.4694.9121.00 28.27C
ATOM8170CD2LEUG21023.715-27.0934.2411.00 34.11C
ATOM8171C LEU G 21025.007 -23.2215.7941.00 37.43C
ATOM8172O LEU G 21024.705 -22.5956.8081.00 36.86O
ATOM8173N GLYG 21125.421 -22.6454.6571.00 38.32N
ATOM8174CA GLY G 21125.472-21.1894.4831.00 38.70C
AIOM8175C GLYG 21124.049 -20.6954.4021.00 39.90C
ATOM8176O GLY G 21123.119-21.5164.4091.00 39.53O
ATOM8177N GLU G 21223.858-19.3754.2991.00 40.32N [0427]ATOM8178CA GLU G 21222.526-18.794 4.544 1.0041.35C
ATOM8179CB GLU G 21222.597-17.2954.8721.0041.54C
ATOM8180CG GLU G 21221.906-16.959 6.208 1.00 44.70C
ATOM8181CD GLU G 21220.408 -16.682 6.092 1.0048.13C
ATOM8182OEl GLU G 21219.935-16.4344.9661.0051.02O
ATOM8183OE2GLUG21219.702-16.6837.1331.00 50.07O
ATOM8184C GLU G 21221.481-19.0523.4661.0040.96C
ATOM8185O GLU G 21220.294-19.1833.7791.0041.23O·
ATOM8186N GLU G 21321.905-19.0992.2091.0040.91N
ATOM8187CA GLU G 21320.971 -19.347 1.102 1.0041.95C
ATOM8188CB GLU G 21321.542-18.898-0.2421.00 42.00C
ATOM8189CG GLU G 21321.141-17.489-0.6571.00 43.48C
ATOM8190CD GLU G 21321.392-17.226-2.1611.0044.93C
ATOM8191OEl GLU G 21321.726-18.194-2.9161.0047.40O
ATOM8192OE2GLUG21321.263-16.041-2.5831.00 46.84O
ATOM8193C GLU G 21320.547-20.8041.0101.0040.90C
ATOM8194O GLU G 21319.386-21.0920.7061.0041.79O
ATOM8195N SERG 21421.479 -21.7221.2451.00 40.03N
ATOM8196CA SER G 21421.108 -23.1241.3201.00 39.29C
ATOM8197CB SER G 21422.312-24.0591.1541.00 39.50C
ATOM8198OG SER G 21422.964 -24.2922.3791.0041.54O
ATOM8199C SER G 21420.262 -23.4302.5831.00 38.07C
ATOM8200O SER G 21419.196 -24.0812.4601.00 36.92O
ATOM8201N TYRG 21520.692 -22.9453.7591.00 35.82N
ATOM8202CA TYR G 21519.828 -22.9964.9841.00 35.68C
ATOM8203CB TYR G 21520.376 -22.1366.1471.00 36.01C
ATOM8204CG TYR G 21519.304-21.6517.1031.00 35.45C
ATOM8205CDl TYR G 21518.765 -22.5028.0801.0036.50C
ATOM8206CE1TYRG21517.742-22.0698.9571.0035.99C
ATOM8207CZ TYR G 21517.266 -20.7658.8661.00 36.29C
ATOM8208OH TYR G 21516.271 -20.3139.7331.00 35.67O
ATOM8209CE2TYRG21517.800-19.8997.8991.0036.18C
ATOM8210CD2 TYRG 21518.814-20.3517.0241.0034.59C
ATOM8211C TYRG21518.353 -22.6544.7131.00 35.47C
ATOM8212O TYRG 21517.445-23.3875.1301.00 35.46O
ATOM8213N LYS G 21618.141 -21.5514.0051.0035.16N
ATOM8214CA LYS G 21616.825-21.0663.6631.00 35.51C
ATOM8215CB LYS G 21616.917-19.6663.0681.00 36.18C
ATOM8216CG LYS G 21617.139-18.5644.0851.00 36.85C
ATOM8217CD LYS G 21617.693-17.3183.4121.0041.41C
ATOM8218CE LYS G 21616.659-16.5692.5851.00 44.26C
ATOM8219NZ LYS G 21617.020-15.1282.5331.0046.25N
ATOM8220C LYS G 21616.111 -21.9622.6621.00 34.92C
ATOM8221O LYS G 21614.887 -21.9982.6501.00 35.11O
[0428]ATOM8222N ASP G 217 16.890 -22.6571.820 1.00 34.72NATOM8223CA ASP G 217 16.385 -23.5970.789 1.00 32.82C
ATOM8224CB ASP G 217 17.518-24.020-0.154 1.0032.90C
ATOM8225CG ASP G 217 17.797 -23.010-1.257 1.0034.38C
ATOM8226ODl ASP G 217 17.053-22.037-1.444 1.00 34.72O
ATOM8227OD2ASPG217 18.795 -23.205-1.963 1.00 38.55O ATOM8228C ASP G 217 15.838-24.8611.411 1.0031.45C
ATOM8229O ASPG217 14.790 -25.3781.016 1.0031.28O
ATOM8230N SERG 218 16.601 -25.3832.355 1.00 30.14N
ATOM8231CA SERG 218 16.235 -26.5573.113 1.0029.29C
ATOM8232CB SER G 218 17.405 -26.9993.990 1.0029.01C
ATOM8233OG SER G 218 18.544-27.3483.198 1.0031.47O
ATOM8234C SERG 218 15.028 -26.2313.966 1.00 28.65C
ATOM8235O SERG 218 14.081 -26.9944.006 1.0029.05O
ATOM8236N THR G 219 15.056-25.0794.626 1.0028.21N
ATOM8237CA THR G 219 14.030 -24.6765.603 1.0027.95C
ATOM8238CB THR G 219 14.421 -23.3346.261 1.00 28.10C
ATOM8239OGl THR G 219 15.399-23.6197.264 1.0029.39O
ATOM8240CG2THRG219 13.248-22.6546.941 1.0029.39C
ATOM8241C THRG 219 12.618-24.6925.035 1.0027.33C
ATOM8242O THR G 219 11.667-24.9435.725 1.0028.32O
ATOM8243N LEU G 220 12.503 -24.4853.753 1.0027.12N
ATOM8244CA LEU G 220 11.215-24.3333.116 1.0026.63C
ATOM8245CB LEU G 220 11.437-23.7091.721 1.0026.19C
ATOM8246CG LEU G 220 10.364-23.0050.907 1.00 29.13C
ATOM8247CDl LEU G 220 9.418-23.9830.277 1.00 32.36C
ATOM8248CD2LEUG220 9.576-22.0161.707 1.00 32.59C
ATOM8249C LEU G 220 10.513-25.6863.045 1.0025.29C
ATOM8250O LEU G 220 9.323 -25.7843.307 1.00 24.82O
ATOM8251N ILE G 221 11.267 -26.7292.713 1.00 24.75N
ATOM8252CA ILE G 221 10.714-28.0792.681 1.00 24.41C
ATOM8253CB ILE G 221 11.517-29.0641.747 1.0025.10C
ATOM8254CGl ILE G 221 11.806 -28.4820.327 1.0024.25C
ATOM8255CDl ILE G 221 10.700-27.623-0.309 1.00 21.02C
ATOM8256CG2ILEG221 10.794-30.3731.692 1.00 22.81C
ATOM8257C ILE G 221 10.558-28.6904.090 1.0023.98C
ATOM8258O ILE G 221 9.638 -29.4764.352 1.0020.56O
ATOM8259N MET G 222 11.462-28.2924.989 1.0023.40N
ATOM8260CA MET G 222 11.412-28.6866.365 1.00 23.49C
ATOM8261CB MET G 222 12.749 -28.3147.029 1.00 24.52C
ATOM8262CG MET G 222 13.905-29.2606.724 1.0019.89C
ATOM8263SD MET G 222 15.431 -28.4977.414 1.00 26.00S
ATOM8264CE MET G 222 15.350-29.3738.988 1.00 12.16C
ATOM8265C MET G 222 10.190-28.1217.141 1.0024.04C
[0429]V L6[οε^ο]
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N：VS'iZOO'l £S8'900&9Z- %ZL'6£32ONlO ML9Z%MOIV
ATOM8354C TRP G 232 -1.013-36.215 13.220 1.00 24.27C
ATOM8355O TRP G 232 -1.364-37.333 13.576 1.00 23.56O
ATOM8356N THR G 233 -0.474 -35.350 14.064 1.00 25.60N
ATOM8357CA THR G 233 -0.161 -35.660 15.433 1.0025.70C
ATOM8358CB THR G 233 1.338-35.220 15.644 1.0025.40C
ATOM8359OGl THR G 233 2.082 -36.243 16.289 1.0026.84O
ATOM8360CG2THRG233 1.431-33.980 16.365 1.00 25.91C
ATOM8361C THRG 233 -1.155-34.840 16.283 1.00 26.17C·
ATOM8362O THR G 233 -1.138-34.905 17.498 1.00 26.50O
ATOM8363N SER G 234 -2.037-34.076 15.626 1.0027.33N
ATOM8364CA SER G 234 -2.923 -33.100 16.290 1.00 28.83C
AIOM8365CB SER G 234 -3.420 -32.072 15.285 1.0028.10C
ATOM8366OG SER G 234 -4.321 -32.705 14.399 1.00 32.95O
ATOM8367C SER G 234 -4.119-33.662 17.062 1.00 30.04C
ATOM8368O SER G 234 -4.425 -34.852 16.959 1.00 30.97O
ATOM8369N ASP G 235 -4.783 -32.802 17.848 1.00 30.90N
ATOM8370CA ASPG 235 -5.902-33.229 18.677 1.0031.09C
ATOM8371CB ASP G 235 -6.108 -32.232 19.829 1.0031.44C
ATOM8372CG ASP G 235 -7.247 -32.634 20.803 1.00 30.29C
ATOM8373ODl ASP G 235 -8.130-31.803 20.986 1.00 32.14O
ATOM8374OD2ASPG235 -7.255 -33.730 21.395 1.0029.55O
ATOM8375C ASPG235 -7.198 -33.408 17.829 1.0031.15C
ATOM8376O ASP G 235 -7.968 -34.326 18.077 1.0031.65O
ATOM8377OXTASP G 235 -7.535 -32.654 16.899 1.00 30.57OTER
ATOM8378N ALAH187 -5.555 -28.203 9.910 1.00 52.90N
ATOM8379CA ALAH187 -5.107-27.734 8.568 1.00 52.13C
ATOM8380CB ALAH187 -3.619-28.031 8.357 1.0051.39C
ATOM8381C ALAH187 -5.962 -28.442 7.527 1.00 52.14C
ATOM8382O ALAH187 -7.004-27.905 7.103 1.00 52.20O
ATOM8383N ALAH188 -5.552 -29.680 7.218 1.00 52.02N
ATOM8384CA ALAH188 -5.890 -30.451 6.003 1.0051.72C
ATOM8385CB ALAH188 -7.411 -30.772 5.873 1.0051.59C
ATOM8386C ALAH188 -5.279 -29.740 4.774 1.0051.62C
ATOM8387O ALAH188 -5.399-30.179 3.610 1.00 52.23O
ATOM8388N ARGH189 -4.595 -28.637 5.078 1.00 50.35N
ATOM8389CA ARGH189 -3.443 -28.208 4.302 1.00 49.16C
ATOM8390CB ARGH189 -2.979 -26.806 4.772 1.00 49.33C
ATOM8391CG ARGH189 -1.500 -26.449 4.562 1.00 49.63C
ATOM8392CD ARGH189 -1.250 -24.951 4.755 1.0051.18C
ATOM8393NE ARGH189 0.143 -24.619 5.094 1.00 55.72N
ATOM8394CZ ARGH189 0.663 -24.658 6.330 1.00 57.77C
ATOM8395NHl ARGII189 -0.074-25.026 7.376 1.00 57.35N
ATOM8396NH2ARGH189 1.940 -24.336 6.525 1.00 58.69N
[0432]ATOM8397C ARG H189-2.381 -29.316 4.5021.00 47.18CATOM8398O ARGH189-1.256 -29.069 4.981 1.0046.88O
ATOM8399N VALH 190-2.775 -30.555 4.1781.0044.76N
ATOM8400CA VALH190-1.806 -31.651 3.971 1.0042.42C
ATOM8401CB VALH190-2.521 -33.000 3.686 1.0043.16C
ATOM8402CGl VALH190-2.786-33.181 2.1841.0043.85C
ATOM8403CG2VALH190-1.720-34.174 4.2401.0043.52C
ATOM8404C VALH190-0.872-31.245 2.8041.0039.57C
ATOM8405O VALH190-1.273 -31.271 1.6451.00 39.05O
ATOM8406N LEUH1910.355 -30.820 3.1291.00 36.08N
ATOM8407CA LEUH191 1.274 -30.286 2.127 1.00 32.47C
ATOM8408CB LEUH191 2.062 -29.054 2.648 1.00 33.45C
ATOM8409CG LEUH191 2.449 -28.570 4.078 1.00 33.40C
ATOM8410CDl LEUH1912.029-27.152 4.3891.00 30.87C
ATOM8411CD2LEUH 1912.045 -29.413 5.2081.0035.28C
ATOM8412C LEUH1912.199 -31.329 1.4691.0029.77C
ATOM8413O LEUH1912.671 -32.257 2.1241.0029.40O
ATOM8414N SEPH1922.427-31.184 0.1621.00 25.83N
ATOM8415CA SEPH 1923.401 -32.023 -0.5751.0022.64C
ATOM8416CB SEPH1922.715-32.907 -1.6891.0020.39C
ATOM8417OG SEPH 1922.201 -32.093 -2.7101.0017.35O
ATOM8418P SEPII1921.169 -32.856 -3.8671.0016.20P
ATOM8419OlP SEP H1920.564-31.663 -4.6811.00 15.63O
ATOM842002P SEPH1920.338-33.876 -3.0991.00 17.70O
ATOM842103P SEP H1922.264 -33.606 -4.7581.00 16.27O
ATOM8422C SEPH1924.365 -31.034 -1.1631.0021.75C
ATOM8423O SEPH1924.170 -29.878 -1.0361.0021.62O
ATOM8424N ALAH1935.385 -31.480 -1.8481.0024.55N
ATOM8425CA ALAH193 6.492 -30.598 -2.222 1.0026.29C
ATOM8426CB ALAH193 7.680 -31.432 -2.651 1.00 25.10C
ATOM8427C ALAH1936.090 -29.674 -3.3601.0028.84C
ATOM8428O ALAH1935.252 -30.061 -4.2171.0028.54O
ATOM8429N PROH1946.730 -28.475 -3.4211.00 30.60N
ATOM8430CA PRO H194 6.639 -27.749 -4.686 1.00 32.08C
ATOM8431CB PROH194 7.286 -26.399 -4.374 1.00 32.42C
ATOM8432CG PRO H194 8.255 -26.694 -3.198 1.0031.67C
ATOM8433CD PRO H194 7.613-27.814 -2.422 1.00 30.40C
ATOM8434C PROH1947.547 -28.623 -5.5351.00 33.32C
ATOM8435O PROH1948.204 -29.502 -4.9671.00 35.47O
ATOM8436N PHEH1957.596-28.504 -6.8461.00 33.64N
ATOM8437CA PHEH195 8.479 -29.447 -7.580 1.00 32.64C
ATOM8438CB PHEH1959.972 -29.067 -7.3541.0031.84C
ATOM8439CG PHEH19510.620 -29.751 -6.196 1.0029.83C
ATOM8440CDl PHEH19511.076 -31.061 -6.3111.00 27.35C
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ATOM8573N GLUI17-14.736-25.119-10.937 1.00 28.12N
ATOM8574CA GLUI17-14.039 -24.019-11.619 1.00 28.80 C
ATOM8575CB GLUI17-12.805 -23.544-10.832 1.00 27.90 C
ATOM8576CG GLUI17-13.108 -23.018 -9.444 1.00 27.05 C
ATOM8577CD GLUI17-11.890 -22.343 -8.832 1.00 29.52 C
ATOM8578OEl GLUI17-10.760 -22.698 -9.211 1.00 32.24O
ATOM8579OE2GLUI17-12.037-21.454 -7.985 1.00 32.13 O
ATOM8580C GLUI17-13.670 -24.351 -13.062 1.0029.12C
ATOM8581O GLUI17-12.617-23.940-13.581 1.0028.79O
ATOM8582N ARGI18-14.552-25.102-13.708 1.0029.74N
ATOM8583CA ARGI18-14.375 -25.448-15.102 1.00 30.39 C ATOM8584CB ARGI18-14.646 -26.949-15.291 1.0031.21 C
ATOM8585CG ARGI18-13.686-27.832-14.520 1.00 30.37 C
ATOM8586CD ARGI18-13.938-29.303-14.767 1.0029.32 C
ATOM8587NE ARGI18-12.629 -29.835-15.003 1.0031.62 N
ATOM8588CZ ARGI18-12.206-30.433-16.108 1.0031.30C
ATOM8589NHl ARGI18-10.932 -30.764-16.152 1.0032.29N
ATOM8590NH2ARGI18-13.012-30.719-17.133 1.0026.72N
ATOM8591C ARGI18-15.358-24.619-15.887 1.00 30.49C
ATOM8592O ARGI18-16.450 -25.083-16.241 1.0031.41O
ATOM8593N TYRI19-14.975 -23.389-16.165 1.00 30.11N
ATOM8594CA TYRI19-15.947 -22.385-16.572 1.00 30.77C
ATOM8595CB TYRI19-15.490-20.951 -16.239 1.00 30.06C
ATOM8596CG TYRI19-15.378 -20.695-14.757 1.00 30.17C
ATOM8597CDl TYRI19-16.515-20.601 -13.963 1.0031.21C
ATOM8598CEl TYRI19-16.425 -20.375-12.573 1.00 32.63C
ATOM8599CZ TYRI19-15.158-20.235-11.982 1.00 30.63C
ATOM8600OH TYRI19-15.066-19.998-10.630 1.00 30.74 O
ATOM8601CE2TYRI19-14.019-20.338-12.756 1.00 28.33C
ATOM8602CD2TYRI19-14.133 -20.573-14.147 1.0027.59C
ATOM8603C TYRI19-16.396-22.484-18.011 1.0031.05C
ATOM8604O TYRI19-17.504-22.043-18.328 1.00 30.34O
ATOM8605N GLUI20-15.545-23.033-18.872 1.0031.76N
ATOM8606CA GLUI20-15.920 -23.212-20.261 1.00 33.34 C
ATOM8607CB GLUI20-14.700-23.348 -21.210 1.00 34.10 C
ATOM8608CG GLUI20-13.440 -24.000 -20.672 1.00 36.66 C
ATOM8609CD GLUI20-12.559 -23.086-19.812 1.0040.99 C
ATOM8610OEl GLUI20-11.765 -22.284 -20.360 1.0040.56O
ATOM8611OE2GLUI20-12.640-23.200-18.572 1.00 43.58O
ATOM8612C GLUI20-17.002-24.302-20.426 1.0033.95C
ATOM8613O GLUI20-17.874-24.209 -21.284 1.00 34.17O
ATOM8614N GLUI21 -16.969 -25.302-19.555 1.0034.64N
ATOM8615CA GLUI21 -18.036 -26.289-19.463 1.00 35.19 C
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X 9ζε/〇3 < g寸寸ZSSI ZoATOM8748OE2GLUI37 -39.271-12.341-20.7051.00 66.69O
ATOM8749 C GLUI37 -36.051-17.222-19.1081.00 59.79C
ATOM8750 O GLUI37-36.721-17.953-18.3641.00 59.32O
ATOM8751N LEUI38-34.749-16.994-18.9461.00 56.84N
ATOM8752 CA LEUI38-33.987-17.565-17.8461.00 53.77C
ATOM8753CB LEUI38-32.501-17.246-18.0351.00 53.69C
ATOM8754CG LEUI38-31.839-17.544-19.3941.00 52.97C
ATOM8755CDl LEUI38-30.357-17.180-19.3881.00 49.95C
ATOM8756CD2LEUI38-32.033-19.002-19.8151.0051.47C
ATOM8757C LEUI38-34.491 -16.984-16.5281.0051.98C
ATOM8758O LEUI38-34.910-15.837-16.5071.0051.45O
ATOM8759N THRI39 -34.483-17.763-15.4441.0049.73N
ATOM8760CA THRI39-34.736-17.176-14.1211.00 48.31C
ATOM8761CB THRI39-34.965-18.219-12.9641.00 48.72C
ATOM8762OGl THRI39-34.772-17.573-11.6981.00 50.02O
ATOM8763CG2THRI39-34.020-19.394-13.0221.00 48.92C
ATOM8764C THRI39-33.635-16.172-13.7441.0046.81C
ATOM8765O THRI39-32.690-15.943-14.5081.0045.69O
ATOM8766N VALI40 -33.796-15.545-12.5881.0045.26N
ATOM8767CA VALI40 -32.758-14.706-12.0361.00 44.51C
ATOM8768CB VALI40 -33.254-13.954-10.7511.0044.66C
ATOM8769CGl VALI40 -32.081 -13.352 -9.9241.00 45.58C
ATOM8770CG2VALI40 -34.252-12.848-11.1331.0043.76C
ATOM8771C YALI40 -31.518-15.601 -11.8241.0044.15C
ATOM8772O VALI40 -30.448-15.320-12.3671.0043.45O
ATOM8773N GLUI41 -31.702-16.705-11.0931.00 43.23N
ATOM8774CA GLUI41-30.657-17.684-10.8481.0042.38C
ATOM8775CB GLUI41-31.245-18.908-10.1591.00 42.97C
ATOM8776CG GLUI41-30.207-19.881 -9.580 1.0045.02C
ATOM8777CD GLUI41 -30.791 -21.272 -9.351 1.0046.83C
ATOM8778OEl GLUI41 -30.629-21.814 -8.2311.0046.23O
ATOM8779OE2GLUI41 -31.426-21.810-10.3001.00 48.12O
ATOM8780C GLUI41 -29.933-18.099-12.1111.0041.45C
ATOM8781O GLUI41 -28.720-17.955-12.1891.0041.00O
ATOM8782N GLUI42-30.680-18.614-13.0931.0040.86N
ATOM8783CA GLUI42 -30.147-18.994-14.4131.00 39.97C
ATOM8784CB GLUI42 -31.261-19.503-15.3211.00 40.61C
ATOM8785CG GLUI42 -31.800-20.887-14.9591.00 42.05C
ATOM8786CD GLUI42-33.075 -21.186-15.6941.0045.72C
ATOM8787OEl GLUI42 -33.632 -20.241-16.2761.00 48.21O
ATOM8788OE2GLUI42 -33.533 -22.352-15.6991.00 47.19O
ATOM8789C GLUI42 -29.386-17.924-15.1901.00 39.27C
ATOM8790O GLUI42-28.347-18.231 -15.8031.00 39.49O
ATOM8791N ARGI43 -29.924-16.701 -15.2211.00 37.89N
[0441]ATOM8792CA ARGI 43 -29.308-15.577-15.933 1.00 37.02CATOM8793CB ARGI 43 -30.298-14.415-16.057 1.00 37.40C
ATOM8794CG ARGI 43 -29.698-12.994-16.203 1.00 38.13C
ATOM8795CD ARGI 43-29.710-12.249-14.852 1.00 36.34C
ATOM8796NE ARGI 43 -30.883-11.413-14.839 1.00 35.41N
ATOM8797CZ ARGI 43 -31.293-10.642-13.846 1.00 34.99C
ATOM8798NHl ARGI 43 -30.620-10.559-12.6971.00 34.64N
ATOM8799NH2ARGI 43 -32.405 -9.942 -14.037 1.00 32.17N
ATOM8800C ARGI 43-28.009-15.121-15.2521.00 36.42C
ATOM8801O ARGI 43 -27.073-14.752-15.9271.00 35.94O
ATOM8802N ASNI 44-27.975-15.153-13.9191.00 35.74N
ATOM8803CA ASNI 44-26.764-14.856-13.149 1.00 35.55C
ATOM8804CB ASNI 44-27.091-14.760-11.6571.00 35.29C
ATOM8805CG ASNI 44-27.832-13.467-11.2851.00 34.78C
ATOM8806ODl ASNI 44-27.828-12.487-12.0391.00 34.10O
ATOM8807ND2ASNI 44-28.443-13.456-10.0961.00 32.37N
ATOM8808C ASNI 44-25.695-15.924-13.3631.0035.63C
ATOM8809O ASNI 44 -24.517-15.621 -13.4311.00 36.08O
ATOM8810N LEUI 45 -26.120-17.179-13.4851.00 35.25N
ATOM8811CA LEUI 45 -25.206-18.304-13.6891.00 34.68C
ATOM8812CB LEUI 45 -25.978-19.627-13.6331.00 34.75C
ATOM8813CG LEUI 45 -25.821-20.663-12.5141.00 35.40C
ATOM8814CDl LEUI 45 -25.142 -20.100-11.2671.00 37.69C
ATOM8815CD2LEUI 45 -27.184 -21.324-12.1941.00 34.03C
ATOM8816C LEUI 45 -24.501 -18.185-15.0321.00 34.43C
ATOM8817O LEUI 45 -23.310-18.459-15.1621.00 34.29O
ATOM8818N LEUI 46 -25.271 -17.792-16.0321.00 33.60N
ATOM8819CA LEUI 46-24.770-17.573-17.3561.00 33.33C
ATOM8820CB LEUI 46-25.933-17.261-18.2901.00 33.50C
ATOM8821CG LEUI 46-25.437-16.692-19.6071.00 35.90C
ATOM8822CDl LEUI 46 -24.723 -17.792 -20.4271.00 36.99C
ATOM8823CD2 LEUI 46 -26.561 -15.952 -20.3921.00 37.08C
ATOM8824C LEUI 46 -23.737-16.436-17.4291.0032.80C
ATOM8825O LEUI 46-22.759-16.535-18.1771.0031.73O
ATOM8826N SERI 47-23.977-15.336-16.7241.0032.76N
ATOM8827CA SERI 47 -23.025-14.233-16.8371.00 33.61C
ATOM8828CB SERI 47 -23.649 -12.833 -16.5761.00 33.44C
ATOM8829OG SERI 47-23.496-12.335-15.2611.00 33.12O
ATOM8830C SERI 47-21.742-14.539-16.0431.00 33.16C
ATOM8831O SERI 47 -20.658-14.241 -16.5261.0033.61O
ATOM8832N VALI 48-21.885-15.171 -14.8701.00 33.06N
ATOM8833CA VALI 48 -20.750-15.744-14.1071.00 32.60C
ATOM8834CB VALI 48 -21.234-16.408-12.7751.00 32.69C
ATOM8835CGl VALI 48 -20.104-17.089-12.0241.00 33.93C
[0442]ATOM8836CG2VALI48-21.835-15.352-11.856 1.00 32.00CATOM8837C VALI48-19.887-16.706-14.955 1.00 32.48C
ATOM8838O VALI48-18.637-16.699-14.849 1.00 32.44O
ATOM8839N ALAI49 -20.543 -17.498-15.824 1.0031.47N
ATOM8840CA ALAI49-19.854-18.473-16.660 1.00 29.86C
ATOM8841CB ALAI49 -20.842-19.404-17.318 1.00 30.98C
ATOM8842C ALAI49-19.016-17.770-17.711 1.00 29.69C
ATOM8843O ALAI49-17.835-18.082-17.882 1.0029.12O·ATOM8844N TYRI50-19.624-16.813-18.417 1.0028.92N
ATOM8845CA TYRI50-18.916-16.059-19.430 1.00 29.13C
ATOM8846CB TYRI50-19.889-15.315-20.330 1.00 29.48C
ATOM8847CG TYRI50-20.203-16.082-21.574 1.00 30.77C
ATOM8848CDl TYRI50-19.275-16.168-22.603 1.0030.58C
ATOM8849CEl TYRI50-19.552-16.865 -23.739 1.00 31.81C
ATOM8850CZ TYRI50-20.777-17.506 -23.865 1.00 30.99C
ATOM8851OH TYRI50 -21.044-18.213-25.008 1.00 32.67O
ATOM8852CE2TYRI50-21.714-17.452 -22.860 1.00 30.83C
ATOM8853CD2TYRI50-21.417-16.745-21.711 1.00 30.50C
ATOM8854C TYRI50-17.879-15.090-18.857 1.0029.00C
ATOM8855O TYRI50-16.811 -14.923-19.419 1.00 27.09O
ATOM8856N LYSI51-18.226-14.461-17.742 1.00 30.06N
ATOM8857CA LYSI51 -17.337-13.507-17.051 1.0031.83C
ATOM8858CB LYSI51-17.994-13.084-15.731 1.0031.91C
ATOM8859CG LYSI51 -17.329-11.987-14.990 1.0036.58C
ATOM8860CD LYSI51 -17.889-11.914-13.545 1.0042.21C
ATOM8861CE LYSI51 -16.910-11.191 -12.584 1.0043.85C
ATOM8862NZ LYSI5 卜17.460-11.148-11.177 1.0042.78N
ATOM8863C LYSI51-15.995-14.146-16.797 1.0031.21C
ATOM8864O LYSI51-14.976-13.580-17.138 1.00 32.23O
ATOM8865N ASNI52-16.016-15.350-16.220 1.0031.85N
ATOM8866CA ASNI52-14.800-16.078-15.785 1.00 30.90C
ATOM8867CB ASNI52-15.167-17.181 -14.818 1.00 30.42C
ATOM8868CG ASNI52-15.504-16.664-13.457 1.00 29.39C
ATOM8869ODl ASNI52-16.666-16.554-13.102 1.0029.22O
ATOM8870ND2ASNI52-14.478-16.356-12.666 1.0028.11N
ATOM8871C ASNI52-13.966-16.657-16.919 1.00 30.93C
ATOM8872O ASNI52-12.743 -16.680-16.826 1.00 30.31O
ATOM8873N VALI53-14.639-17.109-17.976 1.00 30.38N
ATOM8874CA VALI53-14.000-17.510-19.222 1.0030.76C
ATOM8875CB YALI53-15.024-18.224-20.186 1.0031.38C
ATOM8876CGl VALI53-14.364-18.648 -21.499 1.0031.36C
ATOM8877CG2VALI53-15.615-19.429-19.504 1.00 28.79C
ATOM8878C VALI53-13.299-16.363-19.948 1.00 31.10C
ATOM8879O VALI53-12.128-16.506 -20.301 1.0031.57O
[0443]ATOM8968C VALI 641.683 -9.348 -23.155 1.00 42.54C
ATOM8969O VALI 642.834 -9.113-23.551 1.0042.67O
ATOM8970N SERI 650.654 -8.492 -23.285 1.00 43.53N
ATOM8971CA SERI 650.787 -7.148 -23.885 1.0044.88C
ATOM8972CB SERI 65-0.504 -6.350-23.736 1.0044.37C ATOM8973OG SERI 65-1.309 -6.512-24.872 1.0045.61O
ATOM8974C SERI 651.910 -6.368 -23.225 1.00 45.45C
ATOM8975O SERI 652.868 -5.977 -23.867 1.00 45.33O
ATOM8976N SERI 661.754 -6.177 -21.924 1.0046.80N
ATOM8977CA SERI 662.703 -5.519-21.056 1.0048.50C
ATOM8978CB SERI 662.199 -5.660-19.624 1.0047.71C
ATOM8979OG SERI 663.268 -5.647-18.713 1.0049.68O
ATOM8980C SERI 664.164 -6.015-21.185 1.0049.82C
ATOM8981O SERI 665.094 -5.219-21.059 1.00 50.70O
ATOM8982N ILEI 674.354 -7.318-21.415 1.0051.28N
ATOM8983CA ILEI 675.686 -7.906-21.570 1.0051.84C
ATOM8984CB ILEI 675.709 -9.458-21.318 1.0051.83C
ATOM8985CGl ILEI 675.094 -9.821 -19.963 1.00 51.19C
ATOM8986CDl ILEI 674.926-11.328-19.700 1.0051.05C
ATOM8987CG2ILEI 677.151 -10.010-21.440 1.0051.03C
ATOM8988C ILEI 676.167 -7.616-22.988 1.00 52.96C
ATOM8989O ILEI 677.347 -7.363 -23.206 1.00 52.56O
ATOM8990N GLUI 685.238 -7.661 -23.944 1.00 54.35N
ATOM8991CA GLUI 68 5.522 -7.361 -25.346 1.00 56.21C
ATOM8992CB GLUI 684.229 -7.379 -26.147 1.00 55.74C
ATOM8993CG GLUI 68 4.422 -7.489 -27.639 1.00 56.46C
ATOM8994CD GLUI 68 3.153 -7.913-28.371 1.00 56.97C
ATOM8995OEl GLUI 682.374 -8.734 -27.849 1.00 58.80O
ATOM8996OE2GLUI 682.933 -7.437 -29.495 1.00 58.26O
ATOM8997C GLUI 686.219 -6.010-25.514 1.00 57.79C
ATOM8998O GLUI 687.030 -5.833 -26.426 1.00 57.75O
ATOM8999N GLNI 695.903 -5.085 -24.604 1.00 59.67N
ATOM9000CA GLNI 69 6.363 -3.703 -24.639 1.00 61.44C
ATOM9001CB GLNI 69 5.174 -2.776 -24.423 1.0061.66C
ATOM9002CG GLNI 69 4.582 -2.914 -23.021 1.00 63.08C
ATOM9003CD GLNI 69 3.320 -2.089 -22.834 1.00 66.26C
ATOM9004OEl GLNI 693.140 -1.457-21.786 1.00 67.82O
ATOM9005NE2GLNI 692.425 -2.104 -23.837 1.00 66.21N
ATOM9006C GLNI 697.446 -3.413 -23.588 1.00 62.41C
ATOM9007O GLNI 697.932 -2.288 -23.480 1.0062.74O
ATOM9008N LYSI 707.799 -4.407-22.784 1.00 63.68N
ATOM9009CA LYSI 709.064 -4.352 -22.069 1.00 64.97C
ATOM9010CB LYSI 709.114 -5.394 -20.955 1.00 64.93C
ATOM9011CG LYSI 709.646 -4.853 -19.637 1.00 66.01C
[0446]ATOM9056CB ASNI 7615.563 -7.373 -28.313 1.00 69.47C
ATOM9057CG ASNI 7614.731 -7.540-27.052 1.00 69.51C
ATOM9058ODl ASNI 7613.683 -6.917-26.894 1.00 70.88O
ATOM9059ND2ASNI 7615.221 -8.373 -26.130 1.00 68.37N
ATOM9060C ASNI 7613.826 -7.503 -30.197 1.00 68.70C
ATOM9061O ASNI 7613.024 -8.213 -29.593 1.00 68.49O
ATOM9062N GLUI 7713.869 -7.356-31.519 1.00 68.08N
ATOM9063CA GLUI 7713.001 -8.023 -32.490 1.00 67.37 C ATOM9064CB GLUI 7713.702 -8.057 -33.866 1.00 67.65C
ATOM9065CG GLUI 7715.248 -8.254-33.774 1.00 69.42 C
ATOM9066CD GLUI 7716.083 -7.216-34.549 1.00 70.99 C
ATOM9067OEl GLUI 7717.277 -7.506 -34.817 1.0070.78O
ATOM9068OE2GLUI 7715.565 -6.114-34.881 1.00 71.80O
ATOM9069C GLUI 7712.571 -9.398 -31.991 1.0066.23C
ATOM9070O GLUI 7711.562 -9.495 -31.315 1.00 66.22O
ATOM9071N GLUI 7813.321 -10.445 -32.345 1.00 65.34N
ATOM9072CA GLUI 7813.332-11.758-31.651 1.00 64.14C
ATOM9073CB GLUI 7814.649-11.889 -30.852 1.0064.19C
ATOM9074CG GLUI 7815.000-10.614-30.041 1.0064.86C
ATOM9075CD GLUI 7816.066-10.815-28.974 1.00 65.14C
ATOM9076OEl GLUI 7817.053-10.039 -28.963 1.00 66.47O
ATOM9077OE2GLUI 7815.921 -11.738-28.148 1.00 65.71O
ATOM9078C GLUI 7812.117-12.071-30.736 1.00 62.51C
ATOM9079O GLUI 7811.185-12.773 -31.142 1.00 62.42O
ATOM9080N HISI 7912.160-11.537 -29.510 1.0060.69N
ATOM9081CA HISI 7911.146-11.738-28.477 1.00 58.69C
ATOM9082CB HISI 7911.606-11.138-27.148 1.00 58.69C
ATOM9083CG HISI 7912.717-11.902-26.493 1.00 58.04C
ATOM9084NDl HIS I 7913.455-11.393 -25.448 1.00 58.07N
ATOM9085CEl HIS I 7914.359-12.279 -25.072 1.00 57.42C
ATOM9086NE2 HIS I 7914.238 -13.345 -25.841 1.0057.83N
ATOM9087CD2HISI 7913.217-13.137 -26.737 1.00 57.64C
ATOM9088C HISI 799.796-11.178 -28.891 1.00 57.70C
ATOM9089O HISI 798.854-11.956 -29.089 1.00 57.42O
ATOM9090N VALI 809.724 -9.847 -29.060 1.00 56.27N
ATOM9091CA VALI 808.527 -9.128 -29.578 1.0054.72C
ATOM9092CB VALI 808.869 -7.741 -30.219 1.00 54.79C
ATOM9093CGl VALI 807.592 -6.923 -30.514 1.00 54.34C
ATOM9094CG2VALI 809.810 -6.959-29.367 1.00 53.68C
ATOM9095C VALI 807.826 -9.925 -30.661 1.00 53.86C
ATOM 9096O VALI 806.612-10.102 -30.624 1.00 53.70O
ATOM 9097N THRI 818.616-10.399-31.617 1.00 52.75N
ATOM 9098CA THRI 818.110-11.124-32.756 1.0051.86C
ATOM 9099CB THRI 819.257-11.479 -33.744 1.00 52.47C
[0448]ATOM9100OGl THRI 8110.315-10.501 -33.640 1.0051.13OATOM 9101CG2THRI 818.741 -11.522-35.185 1.0051.66C
ATOM 9102C THRI 817.321 -12.350-32.265 1.0051.38C
ATOM 9103O THRI 816.173-12.518-32.652 1.0051.26O
ATOM 9104N LEUI 827.919-13.146-31.365 1.00 50.46N
ATOM 9105CA LEUI 827.290-14.338-30.755 1.0048.85C
ATOM 9106CB LEUI 828.337-15.169 -29.992 1.0049.01C
ATOM 9107CG LEUI 829.321-16.106-30.701 1.0047.35C
ATOM9108CDl LEUI 8210.428-16.451 -29.723 1.0046.50C
ATOM 9109CD2LEUI 828.620-17.363 -31.252 1.0046.99C
ATOM9110C LEUI 826.117-14.047 -29.803 1.00 48.30C
ATOM9111O LEUI 825.109-14.773 -29.815 1.0047.47O
ATOM9112N ILEI 836.276-13.022 -28.962 1.00 47.41N
ATOM9113CA ILEI 835.205 -12.561 -28.076 1.0047.49C
ATOM9114CB ILEI 835.665-11.436-27.093 1.0047.38C
ATOM9115CGl ILEI 837.020-11.770 -26.473 1.0047.39C
ATOM9116CDliLEI 837.693-10.635-25.768 1.0047.04C
ATOM9117CG2ILEI 834.672-11.296-25.963 1.0047.84C
ATOM9118C ILEI 833.959-12.114-28.869 1.0047.58C
ATOM9119O ILEI 832.833-12.434 -28.481 1.0047.99O
ATOM9120N ARGI 844.161 -11.417-29.991 1.0047.14N
ATOM9121CA ARGI 843.055-10.826 -30.742 1.00 47.08C
ATOM9122CB ARGI 843.583 -9.950 -31.882 1.00 48.13C
ATOM9123CG ARGI 842.525 -9.095 -32.595 1.00 50.54C
ATOM9124CD ARGI 843.145 -7.817-33.162 1.00 55.91C
ATOM9125NE ARGI 843.435 -6.831 -32.117 1.00 58.75N
ATOM9126CZ ARGI 844.449 -5.957 -32.133 1.0061.46C
ATOM9127NHl ARGI 845.319 -5.931-33.147 1.00 60.98N
ATOM9128NH2ARGI 844.603 -5.106 -31.110 1.00 62.22N
ATOM9129C ARGI 842.160-11.902-31.297 1.00 45.98C
ATOM9130O ARGI 840.956-11.727 -31.417 1.0045.68O
ATOM9131N GLUI 852.770-13.029 -31.617 1.0044.93N
ATOM9132CA GLUI 852.080 -14.125 -32.248 1.00 44.43C
ATOM9133CB GLUI 853.076 -14.946 -33.090 1.00 44.96C
ATOM9134CG GLUI 854.498-14.270-33.295 1.0049.55C
ATOM 9135CD GLUI 854.597 -13.068 -34.322 1.00 54.45C
ATOM 9136OEl GLUI 853.668 -12.232 -34.432 1.00 57.29O
ATOM 9137OE2GLUI 855.650 -12.932 -35.006 1.00 55.66O
ATOM9138C GLUI 851.332-14.973 -31.198 1.0042.95C
ATOM 9139O GLUI 850.296-15.568 -31.512 1.0041.97O
ATOM 9140N TYRI 861.865-15.018-29.965 1.0041.35N
ATOM 9141CA TYRI 861.185-15.612 -28.787 1.00 40.21C
ATOM 9142CB TYRI 862.155-15.727 -27.592 1.00 39.44C
ATOM 9143CG TYRI 861.704-16.612 -26.415 1.00 38.57C
[0449]ATOM9188CDGLUI 91 -4.864 -9.305 -29.916 1.00 35.11C
ATOM9189OEl GLUI 91 -4.944 -9.372-31.152 1.0037.17O
ATOM9190OE2GLUI 91 -4.170 -8.434-29.346 1.00 36.78O
ATOM9191CGLUI 91 -8.057-13.267 -29.905 1.00 34.32C
ATOM9192OGLUI 91 -9.235-12.954-29.877 1.00 34.59O
ATOM9193NALAI 92 -7.631-14.317-30.607 1.00 34.92N ATOM9194CAALAI 92 -8.603-15.190-31.321 1.00 35.13C
ATOM9195CBALAI 92 -7.886-16.233 -32.200 1.0035.28C
ATOM9196CALAI 92 -9.572 -15.868 -30.360 1.00 35.20C
ATOM9197OALAI 92-10.767-16.082 -30.676 1.00 35.53O
ATOM9198NGLUI 93 -9.058-16.190-29.175 1.00 35.03N
ATOM9199CAGLUI 93 -9.842-16.840-28.150 1.00 35.24C
ATOM9200CBGLUI 93 -8.953-17.290 -27.001 1.00 34.96C
ATOM9201CGGLUI 93 -8.118-18.516-27.240 1.00 34.87C
ATOM9202CDGLUI 93 -7.736-19.212-25.922 1.00 35.11C
ATOM9203OEl GLUI 93 -6.932-20.166 -25.921 1.00 37.88O
ATOM9204OE2GLUI 93 -8.256-18.823 -24.869 1.00 34.64O
ATOM9205CGLUI 93-10.848-15.835-27.648 1.00 35.68C
ATOM9206OGLUI 93-12.045-16.146-27.496 1.00 36.22O
ATOM9207NLEUI 94-10.345-14.621-27.417 1.00 35.97N
ATOM9208CALEUI 94-11.131 -13.517-26.902 1.00 35.70C
ATOM9209CBLEUI 94-10.250-12.316-26.643 1.00 35.21C
ATOM9210CGLEUI 94 -9.458-12.279 -25.341 1.00 34.59C
ATOM9211CDl LEUI 94 -8.549-11.093 -25.366 1.00 30.89C
ATOM9212CD2LEUI 94-10.397-12.170-24.173 1.00 34.91C
ATOM9213CLEUI 94-12.243-13.153 -27.844 1.00 35.77C
ATOM9214OLEUI 94-13.357-12.968 -27.395 1.0036.53O
ATOM9215NSERI 95-11.946-13.084-29.144 1.0036.66N
ATOM9216CASERI 95-12.970-12.943 -30.198 1.00 36.98C
ATOM9217CBSERI 95-12.345-12.849-31.594 1.00 37.10C
ATOM9218OGSERI 95-11.212-11.993 -31.650 1.00 39.06O
ATOM9219CSERI 95-14.012-14.075 -30.198 1.00 37.41C
ATOM9220OSERI 95-15.201-13.811 -30.299 1.00 37.11O
ATOM9221NLYSI 96-13.568-15.324-30.094 1.0038.07N
ATOM9222CALYSI 96-14.497-16.462-30.137 1.00 38.92C
ATOM9223CBLYSI 96-13.735-17.795 -30.379 1.00 38.46C
ATOM9224CGLYSI 96-13.627-18.831-29.234 1.0040.58C
ATOM9225CDLYSI 96-12.266-19.666-29.248 1.0040.52C
ATOM9226CELYSI 96-11.641-19.843 -30.679 1.0043.64C
ATOM9227NZLYSI 96-10.111-19.647 -30.759 1.0040.41N
ATOM9228CLYSI 96-15.456-16.461 -28.918 1.00 38.69C
ATOM9229OLYSI 96-16.666-16.739 -29.058 1.0038.39O
ATOM9230NILEI 97-14.928-16.091-27.749 1.00 38.23N
ATOM9231CAILEI 97-15.735-16.059-26.520 1.00 38.26C
[0451]ATOM9232CB ILEI 97-14.862-15.939-25.214 1.00 37.99CATOM9233CGl ILEI 97-13.940-17.153-25.045 1.0037.49C
ATOM9234CDl ILEI 97-12.656-16.876 -24.218 1.0038.09C
ATOM9235CG2ILEI 97-15.750-15.750-23.973 1.00 36.78C
ATOM9236C ILEI 97-16.776-14.920-26.605 1.00 38.71C
ATOM9237O ILEI 97-17.972-15.132-26.332 1.0038.57O
ATOM9238N CYSI 98-16.309-13.730-26.995 1.00 39.00N
ΑΓΟΜ9239CA CYSI 98-17.178-12.574-27.157 1.00 39.25C·
ATOM9240CB CYSI 98-16.366-11.335-27.502 1.00 38.81C
ATOM9241SG CYSI 98-15.458-10.624 -26.097 1.00 37.31S
ATOM9242C CYSI 98-18.258-12.825 -28.208 1.00 40.37C
ATOM9243O CYSI 98-19.430-12.531-27.967 1.0041.06O
ATOM9244N ASPI 99-17.870-13.392-29.350 1.0041.06N
ATOM9245CA ASPI 99-18.801 -13.720-30.425 1.00 41.96C
ATOM9246CB ASPI 99-18.061-14.280 -31.640 1.00 42.99C
ATOM9247CG ASPI 99-18.928-14.313-32.900 1.00 46.92C
ATOM9248ODl ASPI 99-18.590-13.600-33.887 1.00 51.17O
ATOM9249OD2ASPI 99-19.938-15.054 -32.914 1.00 48.11O
ATOM9250C ASPI 99-19.811 -14.729 -29.958 1.0041.53C
ATOM9251O ASPI 99 -20.961-14.686 -30.376 1.0041.18O
ATOM9252N GLYI 100 -19.375 -15.630 -29.078 1.0041.37N
ATOM9253CA GLYI 100 -20.223 -16.711 -28.604 1.0040.33C
ATOM9254C GLYI 100 -21.418 -16.161 -27.875 1.0040.26C
ATOM9255O GLYI 100-22.565-16.559-28.154 1.0040.30O
ATOM9256N ILEI 101 -21.141 -15.244-26.939 1.00 39.26N
ATOM9257CA ILE1 101 -22.167 -14.690 -26.054 1.00 38.33C
ATOM9258CB ILE1 101 -21.586 -14.057 -24.746 1.00 37.60C
ATOM9259CGl ILE1 101 -22.678 -13.347 -23.946 1.00 36.13C
ATOM9260CDl ILEI 101 -23.584-14.253 -23.179 1.00 33.85C
ATOM9261CG2ILEI 101 -20.451 -13.095 -25.037 1.00 37.77C
ATOM9262C ILEI101 -23.002-13.657 -26.756 1.00 38.42C
ATOM9263O ILE1 101 -24.203 -13.544 -26.484 1.00 38.58O
ATOM9264N LEU1102 -22.365 -12.897 -27.637 1.00 38.54N
ATOM9265CA LEUI 102-23.046-11.822-28.333 1.00 39.43C
ATOM9266CB LEUI 102-22.058-10.850-28.998 1.00 39.40C
ATOM9267CG LEUI102-21.339 -9.925 -27.987 1.00 38.47C
ATOM9268CDl LEUI 102-22.298 -8.870 -27.433 1.00 36.17C
ATOM9269CD2 LEU1 102-20.060 -9.290 -28.543 1.00 37.91C
ATOM9270C LEU1102 -24.114 -12.385 -29.279 1.0040.45C
ATOM9271O LEUI102 -25.258 -11.939 -29.214 1.0041.36O
ATOM9272N LYS1103 -23.767 -13.384 -30.099 1.00 41.22N
ATOM9273CA LYS1 103 -24.772 -14.124 -30.903 1.0041.75C
ATOM9274CB LYS1 103-24.216-15.454-31.450 1.0041.85C
ATOM9275CG LYS1 103 -23.048 -15.398 -32.470 1.0042.93C
[0452]ATOM9276CD LYS1103 -23.436 -14.955 -33.925 1.0045.56CATOM9277CE LYS1103 -22.207 -14.952 -34.915 1.0044.75C
ATOM9278NZ LYS1103 -22.368 -14.046 -36.133 1.0042.89N
ATOM9279C LYS1 103 -25.991 -14.435 -30.031 1.0042.00C
ATOM9280O LYS1103 -27.130 -14.122 -30.386 1.0042.54O
ATOM9281N LEUI104-25.735 -15.024-28.868 1.0041.73N
ATOM9282CA LEUI 104-26.797-15.461 -27.968 1.0041.87C
ATOM9283CB LEU1 104 -26.203 -16.242 -26.789 1.0041.30C
ATOM9284CG LEUI 104-27.139-16.867-25.754 1.0041.84C
ATOM9285CDl LEU1104 -28.252 -17.732 -26.404 1.0041.72C
ATOM9286CD2 LEU1104 -26.325 -17.685 -24.764 1.0041.59C
ATOM9287C LEU1104 -27.669 -14.305 -27.475 1.0041.97C·
ATOM9288O LEU1104 -28.889 -14.460 -27.296 1.0042.35O
ATOM9289N LEUI105 -27.045 -13.148 -27.255 1.0041.76N
ATOM9290CA LEUI 105 -27.772 -11.971 -26.783 1.0041.03C
ATOM9291CB LEUI 105 -26.798 -10.887 -26.263 1.00 40.36C
ATOM9292CG LEUI 105 -26.102 -11.195 -24.929 1.00 38.09C
ATOM9293CDl LEU1105 -27.010 -10.937 -23.745 1.0035.26C
ATOM9294CD2 LEU1105 -24.800 -10.422 -24.778 1.0038.49C
ATOM9295C LEU1105 -28.692 -11.449 -27.897 1.0042.05C
ATOM9296O LEUI105 -29.893 -11.238 -27.695 1.0042.09O
ATOM9297N ASPT106 -28.109-11.275-29.077 1.00 43.33N
ATOM9298CA ASPI 106 -28.805 -10.724 -30.228 1.00 44.76C
ATOM9299CB ASP 1106 -27.802 -10.449 -31.367 1.0044.59C
ATOM9300CG ASPI106 -26.761 -9.340-30.993 1.0047.20C
ATOM9301ODl ASP 1 106 -26.937 -8.656 -29.950 1.00 48.16O
ATOM9302OD2 ASP Il 06-25.764 -9.148 -31.733 1.00 47.12O
ATOM9303C ASPI 106 -29.993 -11.610-30.677 1.00 45.59C
ATOM9304O ASPI 106 -31.038 -11.095 -31.073 1.0045.58O
ATOM9305N SERI 107 -29.848 -12.928 -30.559 1.0046.17N
ATOM9306CA SERI 107 -30.821 -13.862 -31.126 1.00 46.85C
ATOM9307CB SERI 107-30.102-15.044-31.794 1.00 46.49C
ATOM9308OG SERI 107-29.549-15.913-30.820 1.00 47.97O
ATOM9309C SERI 107 -31.871 -14.345 -30.113 1.0047.27C
ATOM9310O SERI 107 -33.040-14.559-30.476 1.00 47.93O
ATOM9311N fflS 1108 -31.461 -14.507 -28.858 1.0047.08N
ATOM9312CA HIS 1108 -32.326 -15.055 -27.821 1.00 47.22C
ATOM9313CB HIS 1108 -31.715 -16.343 -27.243 1.0047.66C
ATOM9314CG HIS 1108 -31.899 -17.555 -28.105 1.0047.71C
ATOM9315NDl HIS 1108 -31.183 -17.762 -29.268 1.0047.93N
ATOM9316CEl HIS 1 108 -31.551-18.908-29.810 1.0046.40C
ATOM9317NE2 HIS 1 108 -32.467 -19.458 -29.034 1.00 47.55N
ATOM9318CD2 HIS 1108 -32.698 -18.635 -27.958 1.00 47.17C
ATOM9319C IIIS1108 -32.577 -14.100 -26.653 1.00 47.25C
[0453]
[0455]ATOM9408CZ PHEI 121 -26.645-10.486-15.3541.00 33.16CATOM9409CE2PHEI 121-27.136 -9.449-14.5451.0031.30C
ATOM9410CD2PHEI 121 -28.106 -8.569-15.0531.00 33.35C
ATOM9411C PHEI121 -28.385 -7.018-18.9061.00 33.30C
ATOM9412O PHEI 121 -27.146 -6.935 -19.0261.00 33.09O
ATOM9413N TYRI 122 -29.194 -7.462-19.8561.0031.93N
ATOM9414CA TYRI 122 -28.690 -8.039-21.0791.00 30.06C
ATOM9415CB TYRI 122-29.817 -8.846 -21.7611.00 30.63C`
ATOM9416CG TYRI 122 -30.204-10.104-21.0001.00 28.61C
ATOM9417CDl TYRI 122 -29.230 -11.032 -20.5931.00 26.61C
ATOM9418CEl TYRI 122 -29.590 -12.204 -19.9001.0029.02C
ATOM9419CZ TYRI 122 -30.951 -12.448-19.6361.00 28.97C
ATOM9420OH TYRI 122-31.333 -13.571 -18.9621.0029.12O
ATOM9421CE2TYRI 122 -31.918-11.533 -20.0091.00 27.57C
ATOM9422CD2TYRI 122 -31.545 -10.376 -20.7031.0028.06C
ATOM9423C TYRI 122 -28.104 -7.000 -22.0181.00 29.16C
ATOM9424O TYRI 122-27.168 -7.280-22.7681.00 28.70O
ATOM9425N LEUI 123 -28.651 -5.797-21.9821.00 28.48N
ATOM9426CA LEUI 123 -28.129 -4.735 -22.8121.00 28.72C
ATOM9427CB LEUI 123 -29.111 -3.584 -22.9241.00 28.57C
ATOM9428CG LEUI 123 -30.231 -3.794-23.9511.0028.45C
ATOM9429CDl LEUI 123 -31.410 -2.914-23.5211.0025.92C
ATOM9430CD2 LEU1123-29.733 -3.508 -25.4051.0025.33C
ATOM9431C LEUI 123 -26.795 -4.237 -22.3051.0029.11C
ATOM9432O LEU1 123 -25.947 -3.921 -23.1221.0029.73O
ATOM9433N LYS1124-26.634 -4.152 -20.9801.0029.11N
ATOM9434CA LYS1 124 -25.303 -3.894-20.3441.00 30.84C
ATOM9435CB LYS1 124 -25.428 -3.859-18.8151.00 29.33C
ATOM9436CG LYS1 124-24.111 -3.761 -18.0831.00 30.67C
ATOM9437CD LYS1 124-24.318 -3.839-16.5831.0026.10C
ATOM9438CE LYS1 124-23.167 -4.578-15.8941.00 24.94C
ATOM9439NZ LYS1 124 -22.706 -5.746-16.6751.00 21.30N
ATOM9440C LYSI 124-24.358 -5.009 -20.7671.0031.71C
ATOM9441O LYS1124-23.221 -4.762-21.1631.00 32.60O
ATOM9442N METI 125 -24.873 -6.236-20.7521.00 32.71N
ATOM9443CA METI 125 -24.063 -7.410-21.0311.0034.18C
ATOM9444CB METI 125 -24.879 -8.690 -20.8041.00 33.91C
ATOM9445CG METI 125 -24.083 -9.925 -20.3641.00 35.32C
ATOM9446SD METI 125-25.109-11.438-20.3471.00 36.20S
ATOM9447CE METI 125 -23.868-12.609-19.8741.00 35.54C
ATOM9448C METI125-23.518 -7.319-22.4511.00 33.54C
ATOM9449O METI 125 -22.307 -7.503 -22.6801.00 33.82O
ATOM9450N LYSI 126-24.407 -6.966 -23.3771.0033.36N
ATOM9451CA LYS1 126 -24.062 -6.727-24.7821.00 32.70C
[0456]
[0457]ATOM9496CG ARGI131 -15.449 -2.226-22.5221.0027.69 CATOM9497CD ARGI131 -16.004 -1.373-21.3531.0025.92 C
ATOM9498NE ARGI131 -16.867 -2.117-20.4121.0024.96 N
ATOM9499CZ ARGI131-16.445 -2.903 -19.4231.0023.72 C
ATOM9500NHl ARGI 131 -15.148 -3.045 -19.1761.0025.88N
ATOM9501NH2ARGI 131-17.326 -3.523-18.6461.00 20.94N
ATOM9502C ARGI 131-14.908 -4.309 -24.7121.0028.32C
ATOM9503O ARGI 131-13.838 -3.883 -25.1301.00 30.11O
ATOM9504N TYRI 132-15.059 -5.560-24.2621.0028.02N
ATOM9505CA TYRI132-13.927 -6.503 -24.2231.0027.35 C
ATOM9506CB TYRI132-14.337 -7.858 -23.6471.0026.06 C
ATOM9507CG TYRI132-15.026 -7.723 -22.3271.0024.72 C
ATOM9508CDl TYRI 132-16.051 -8.582 -21.9721.0021.09C
ATOM9509CEl TYRI132-16.691 -8.454-20.7541.00 23.39C
ATOM9510CZ TYRI 132-16.311 -7.458-19.8671.0023.55C
ATOM9511OH TYRI132-16.973 -7.346-18.6581.0023.96 O
ATOM9512CE2 TYRI 132-15.300 -6.588 -20.1981.0021.37C
ATOM9513CD2 TYR1 132-14.669 -6.707 -21.4211.00 23.92C
ATOM9514C TYRI 132-13.209 -6.661 -25.5551.0028.14C
ATOM9515O TYRl 132-11.973 -6.758 -25.5911.0027.97O
ATOM9516N LEUI133-13.983 -6.669 -26.6451.00 29.26N
ATOM9517CA LEUI133-13.429 -6.606 -28.0081.00 30.05C
ATOM9518CB LEUI 133-14.545 -6.668 -29.0471.00 30.06C
ATOM9519CG LEUI 133-15.267 -7.987 -29.3231.00 30.71C
ATOM9520CDl LEUI 133-16.220 -7.787 -30.5191.00 32.35C
ATOM9521CD2 LEU1 133-14.252 -9.107-29.6081.0028.71C
ATOM9522C LEUI133-12.687 -5.312-28.2111.00 30.70C
ATOM9523O LEUI133-11.583 -5.309-28.7571.00 30.93O
ATOM9524N ALAI 134-13.302 -4.213 -27.7721.0031.52N
ATOM9525CA ALAI 134-12.742 -2.878 -27.9441.00 32.87C
ATOM9526CB ALAI 134-13.784 -1.820-27.5931.00 32.95C
ATOM9527C ALAI 134-11.433 -2.696-27.1371.00 33.21C
ATOM9528O ALAI 134-10.579 -1.891 -27.4981.00 34.15O
ATOM9529N GLUI 135-11.259 -3.495 -26.0901.00 33.44N
ATOM9530CA GLUI 135 -9.976 -3.596 -25.3811.00 34.05 C
ATOM9531CB GLUI135-10.133 A534-24.1981.00 32.84C
ATOM9532CG GLUI 135-10.845 -3.871 -23.0651.00 32.44 C
ATOM9533CD GLUI 135-10.992 -4.792-21.9091.0028.70 C
ATOM9534OEl GLUI 135-11.615 -4.430-20.9041.0027.00O
ATOM9535OE2 GLUI 135-10.456 -5.896-22.0091.0031.79O
ATOM9536C GLUI135 -8.757 -4.018 -26.2341.00 34.11C
ATOM9537O GLUI 135 -7.616 -3.651 -25.9351.00 33.42 O
ATOM9538N PHEI136 -8.981 -4.784 -27.2911.00 34.58N
ATOM9539CA PHEI 136 -7.827 -5.294 -28.0621.0035.70 C
[0458]
[0459]ATOM9584CAARGI 142-12.207 -1.363 -32.6691.00 44.02 CATOM9585CBARGI 142-10.844 -0.699 -32.4361.0043.41 C
ATOM9586CGARGI 142-10.769 0.046-31.146 1.00 43.15 C
ATOM9587CDARGI 142 -9.355 0.394 -30.756 1.0046.30 C
ATOM9588NEARGI 142 -9.321 1.530-29.826 1.0049.99 N
ATOM9589CZARGI 142 -9.557 1.475 -28.512 1.0051.53 C
ATOM9590NHl ARG1 142 -9.497 2.582 -27.782 1.00 51.56 N
ATOM9591NH2ARGI 142 -9.851 0.327-27.9111.00 53.51 N
ATOM9592CARGI 142-13.312 -0.301 -32.6941.0044.54C
ATOM9593OARGI 142-14.059 -0.123 -31.7041.00 43.91O
ATOM9594NLYSI143-13.415 0.365 -33.8541.0044.98N
ATOM9595CALYS1 143 -14.332 1.478 -34.0921.0045.84C
ATOM9596CBLYS1143-14.030 2.141 -35.4411.0046.38C
ATOM9597CGLYSI 143-13.682 3.645 -35.3621.0048.30C
ATOM9598CDLYS1 143-12.401 3.921 -34.5041.0049.97C
ATOM9599CELYS1143-11.644 5.215-34.9171.0049.07C
ATOM9600NZLYSI143-10.440 4.925 -35.7981.00 49.32N
ATOM9601CLYSI 143-15.775 1.024-34.0591.00 45.77C
ATOM9602OLYSI 143-16.636 1.734 -33.5411.0045.80O
ATOM9603NGLUI144-16.033 -0.156 -34.6111.0045.52N
ATOM9604CAGLUI 144-17.378 -0.717-34.5811.00 46.10C
ATOM9605CBGLUI 144-17.552 -1.714-35.7171.00 46.63C
ATOM9606CGGLUI 144-18.975 -2.168 -35.8671.0049.87C
ATOM9607CDGLUI 144-19.081 -3.674-35.9341.00 54.43C
ATOM9608OEl GLUI 144-18.592 -4.224 -36.9551.00 55.67O
ATOM9609OE2 GLU1144-19.649 -4.292 -34.9761.00 54.77O
ATOM9610CGLUI 144-17.742 -1.375 -33.2391.0045.24C
ATOM9611OGLUI 144-18.928 -1.529 -32.9091.0045.40O
ATOM9612NALAI 145-16.730 -1.774 -32.4701.0044.13N
ATOM9613CAALAI 145 -16.981 -2.334-31.1541.00 43.15C
ATOM9614CBALAI 145 -15.764 -3.119-30.6531.00 43.22C
ATOM9615CALAI 145-17.337 -1.189 -30.2171.0042.42C
ATOM9616OALAI 145-18.312 -1.265 -29.4641.0042.48O
ATOM9617NALAI 146-16.558 -0.114-30.2911.0042.25N
ATOM9618CAALAI 146-16.790 1.078 -29.4731.00 41.88C
ATOM9619CBALAI 146-15.686 2.120-29.7081.00 42.07C
ATOM9620CALAI 146-18.170 1.688-29.7271.0041.72C
ATOM9621OALAI 146-18.840 2.143 -28.7991.0041.19O
ATOM9622NGLUI147-18.578 1.695 -30.9921.0041.53N
ATOM9623CAGLUI 147-19.874 2.215-31.3871.0041.99 C
ATOM9624CBGLUI 147-19.951 2.359-32.9161.0041.71C
ATOM9625CGGLUI 147-19.058 3.497 -33.4391.00 44.54 C
ATOM9626CDGLUI 147-19.345 3.915-34.9071.0045.48 C
ATOM9627OEl GLUI 147-19.423 5.144-35.1651.0047.68O
[0460]ATOM9628OE2 GLUI147-19.4723.027 -35.7971.0049.56OATOM9629C GLUI147-21.0121.356-30.8341.00 40.48C
ATOM9630O GLUI 147 -22.0121.875 -30.3121.0041.02O
ATOM9631N SERI 148 -20.8550.041 -30.9261.00 39.03N
ATOM9632CA SERI 148 -21.896-0.872 -30.4831.00 36.84C
ATOM9633CB SERI 148 -21.638-2.271-31.0461.00 37.80C
ATOM9634OG SERI 148 -21.650-2.272-32.4711.00 37.28O
ATOM9635C SERI 148 -22.047-0.893 -28.9581.0035.72C
ATOM9636O SERI 148 -23.117-1.205 -28.4521.00 34.20O
ATOM9637N THRI149 -20.968-0.546 -28.2361.0034.92N
ATOM9638CA THRI 149-20.969-0.470 -26.7681.00 33.52C ATOM9639CB THRI 149-19.513-0.304-26.1601.00 32.91C
ATOM9640OGl THRI149-18.625-1.282-26.7021.00 33.80O
ATOM9641CG2 THRI 149-19.527-0.536 -24.7271.00 30.55C
ATOM9642C THRI149 -21.8290.708 -26.3191.00 33.55C
ATOM9643O THRI149 -22.7010.558 -25.4331.00 32.86O
ATOM9644N METI150 -21.5781.866-26.9471.00 33.61N
ATOM9645CA METI 150 -22.4153.074-26.8101.00 33.71C
ATOM9646CB METI 150 -21.9744.153 -27.8081.00 34.29C
ATOM9647CG MET I] 50-22.4635.568 -27.4451.00 36.13C
ATOM9648SD METI150-21.8636.137-25.8311.0040.42S
ATOM9649CE METI 150 -20.3096.878 -26.3381.00 36.72C
ATOM9650C METI150 -23.9142.794-26.9791.00 33.38C
ATOM9651O METI150-24.7022.987 -26.0311.00 33.11O
ATOM9652N THRI151 -24.2972.342-28.1801.00 32.40N
ATOM9653CA THRI 151 -25.6931.963 -28.4831.00 32.59C
ATOM9654CB THRI 151 -25.8081.225 -29.8431.00 32.49C
ATOM9655OGl THRI151-25.1461.987-30.8681.00 33.48O
ATOM9656CG2 THR Il 51 -27.2641.028 -30.2511.00 32.80C
ATOM9657C THRI151-26.3061.103 -27.3861.00 31.64C
ATOM9658O THRI151 -27.4011.367 -26.9231.0030.86O
ATOM9659N ALAI 152 -25.5550.098 -26.9581.00 32.58N
ATOM9660CA ALAI 152-26.027-0.889-25.9931.00 33.33C
ATOM9661CB ALAI 152 -25.095-2.093 -25.9821.00 33.44C
ATOM9662C ALAI 152 -26.156-0.300 -24.6071.00 33.81C
ATOM9663O ALAI 152 -27.180-0.512-23.9451.0033.51O
ATOM9664N TYRI153 -25.1310.470 -24.2071.0034:61N
ATOM9665CA TYRI153 -25.0781.165 -22.9181.00 35.18C
ATOM9666CB TYRI153 -23.6511.652-22.6151.00 35.26C
ATOM9667CG TYRI153 -22.6970.610-22.0541.00 34.75C
ATOM9668CDl TYRI153 -23.168-0.520-21.3631.00 34.24C
ATOM9669CEl TYRI153 -22.298-1.474-20.8371.00 32.48C
ATOM9670CZ TYRI153 -20.922-1.278 -20.9601.00 35.46C
ATOM9671OH TYRI 153 -20.035-2.194-20.4361.00 34.11O
[0461]ATOM9672CE2 TYR1153-20.424-0.155 -21.625 1.00 34.42CATOM9673CD2 TYRI153-21.314 0.789 -22.159 1.00 35.33C
ATOM9674C TYRI153 -26.0622.329 -22.767 1.00 35.95C
ATOM9675O TYRI153 -26.608 2.508 -21.675 1.00 36.20O ATOM9676N LYSI 154-26.2883.122-23.831 1.0037.02N
ATOM9677CA LYS1 154-27.380 4.128 -23.804 1.00 37.28C
ATOM9678CB LYSI154 -27.278 5.262 -24.855 1.00 37.55C
ATOM9679CG LYSI 154-26.743 4.930-26.209 1.0039.11C
ATOM9680CD LYS1154 -27.403 5.790 -27.299 1.0043.63C
ATOM9681CE LYSI ] 54-26.6045.788 -28.643 1.0044.66C
ATOM9682NZ LYS1154-27.415 5.293 -29.810 1.00 41.96N
ATOM9683C LYSI154 -28.7843.515 -23.769 1.00 37.51C
ATOM9684O LYSI 154-29.6203.961 -22.978 1.00 37.52O
ATOM9685N ALAI 155-29.0302.499 -24.601 1.00 37.40N
ATOM9686CA ALAI 155 -30.305 1.752-24.586 1.00 37.44C
ATOM9687CB ALAI 155-30.271 0.650-25.624 1.00 37.66C
ATOM9688C ALAI 155-30.6051.164-23.216 1.00 37.49C
ATOM9689O ALAI 155-31.706 1.291 -22.693 1.00 38.70O
ATOM9690N ALAI 156-29.6120.512-22.641 1.00 37.49N
ATOM9691CA ALAI 156-29.658 0.048 -21.262 1.00 37.46C
ATOM9692CB ALAI 156 -28.290-0.619 -20.887 1.00 36.77C
ATOM9693C ALAI 156 -29.9571.210-20.301 1.00 37.40C
ATOM9694O ALAI 156 -30.721 1.065-19.354 1.00 37.14O
ATOM9695N GLNI 157-29.303 2.347-20.550 1.00 38.40N
ATOM9696CA GLNI 157 -29.342 3.521 -19.664 1.00 38.49 C
ATOM9697CB GLNI 157 -28.289 4.542 -20.098 1.00 38.38C
ATOM9698CG GLNI 157 -27.981 5.586-19.057 1.00 39.29 C
ATOM9699CD GLNI 157-27.141 6.728-19.611 1.0040.08C
ATOM9700OEl GLNI157 -27.2637.094 -20.792 1.0041.09O
ATOM9701NE2 GLNI157-26.2967.298-18.764 1.00 38.04N
ATOM9702C GLNI157-30.7124.176-19.678 1.0037.98C
ATOM9703O GLNI157 -31.180 4.658-18.662 1.00 36.42O
ATOM9704N ASPI 158-31.3334.192 -20.858 1.00 39.03N
ATOM9705CA ASPI158-32.709 4.708 -21.011 1.00 39.53C
ATOM9706CB ASPI158-33.0984.822 -22.481 1.0039.90C
ATOM9707CG ASPI158-32.351 5.924-23.172 1.0040.49C
ATOM9708ODl ASPI158-32.2045.873 -24.402 1.0042.76O
ATOM9709OD2 ASP 1158-31.8636.833 -22.467 1.0043.32O
ATOM9710C ASPI158 -33.7113.904 -20.221 1.00 39.23C
ATOM9711O ASPI 158 -34.5374.472 -19.499 1.0040.01O
ATOM9712N ILEI 159 -33.6122.585 -20.308 1.0039.15N
ATOM9713CA ILEI 159-34.4661.740-19.491 1.0039.03C
ATOM9714CB ILEI159 -34.4600.267 -19.980 1.00 38.81C
ATOM9715CGl ILE1 159 -35.0550.174-21.391 1.00 38.64C
[0462]ATOM9716CDl ILEI 159 -34.460-0.904-22.2651.00 38.81CATOM9717CG2ILE1 159 -35.299-0.598-19.0691.00 38.95C
ATOM9718C ILEI159 -34.0751.913-18.0131.00 39.23C
ATOM9719O ILEI 159 -34.9402.037-17.1381.00 38.46O
ATOM9720N ALAI 160-32.7651.960-17.7581.00 39.59N
ATOM9721CA ALAI 160 -32.230 2.122-16.402 1.00 39.17C·
ATOiM9722CB ALAI 160 -30.695 2.245-16.436 1.00 39.60C
ATOM9723C ALAI 160 -32.8523.315-15.6991.0038.71C
ATOM9724O ALAI 160 -33.4803.175-14.6581.00 38.32O
ATOM9725N LEUI161 -32.6944.481 -16.3001.00 38.74N
ATOM9726CA LEUI161 -33.138 5.746-15.710 1.0040.09C
ATOM9727CB LEUI161-32.5856.900-16.5601.0040.39C
ATOM9728CG LEUI161-31.2937.664-16.187 1.0042.44C
ATOM9729CDl LEUI161 -30.5077.111-15.0101.0044.12C
ATOM9730CD2 LEU Π 61-30.3647.852-17.4171.00 43.47C
ATOM9731C LEUI161 -34.6645.889-15.4951.00 39.98C
ATOM9732O LEUI161-35.1226.408-14.4761.00 38.90O
ATOM9733N ALAI 162-35.4395.403 -16.4691.0041.13N
ATOM9734CA ALAI 162-36.8915.482-16.444 1.00 40.89C
ATOM9735CB ALAI 162-37.4555.376-17.8831.00 40.98C
ATOM9736C ALAI 162-37.5264.452-15.5081.0041.21C
ATOM9737O ALAI 162-38.4284.785-14.7361.0041.47O
ATOM9738N ASPI 163 -37.0463.211-15.5371.0041.41N
ATOM9739CA ASPI163 -37.7432.124-14.8231.0041.61C
ATOM9740CB ASPI163 -38.0740.992-15.8101.00 42.35C
ATOM9741CG ASPI163 -39.0081.458-16.9181.0043.90C
ATOM9742ODl ASPI163 -40.0831.991-16.5721.0045.92O
ATOM9743OD2 ASPI 163-38.6581.345-18.1151.0045.77O
ATOM9744C ASPI163 -37.1671.565-13.4971.0041.06C
ATOM9745O ASPI163 -37.9281.013-12.6771.0040.75O
ATOM9746N LEUI 164-35.8521.703-13.2871.00 39.73N
ATOM9747CA LEUI 164-35.1871.126-12.0921.00 38.02C
ATOM9748CB LEUI 164-33.9150.323 -12.4651.0037.53C
ATOM9749CG LEUI 164-33.872-0.760 -13.5671.0038.04C
ATOM9750CDl LEUI 164-32.488-1.438-13.6041.00 36.71C
ATOM9751CD2 LEU1164-34.925-1.822-13.4061.0034.83C
ATOM9752C LEUI 164-34.8432.225-11.0961.00 36.85C
ATOM9753O LEU1164-34.6423.366-11.4811.0035.23O
ATOM9754N ALAI 165 -34.7731.851 -9.8191.0036.49N
ATOM9755CA ALAI 165 -34.465 2.770 -8.734 1.0036.47 C
ATOM9756CB ALAI 165 -34.9232.150 -7.419 1.00 36.91 C
ATOM9757C ALAI 165 -32.9573.076 -8.7031.00 36.36C
ATOM9758O ALAI 165 -32.1662.248 -9.1081.00 36.45O
ATOM9759N PROI166 -32.5434.267 -8.2181.00 36.91N
[0463]ATOM 9760CA PROI 166-31.103 4.619 -8.342 ] .00 36.69CATOM 9761CB PRO Il 66 -31.040 6.057 -7.792 1.0037.17C
ATOM9762CG PROI166 -32.424 6.566 -7.983 1.00 37.21C
ATOM9763CD PROI166 -33.294 5.373 -7.601 1.00 36.14C
ATOM9764C PROI166 -30.182 3.693 -7.569 1.00 36.58C
ATOM 9765O PROI 166-29.008 3.573 -7.888 1.00 37.26O
ATOM 9766N THRI 167 -30.752 3.008 -6.592 1.00 36.60N ATOM 9767CA THRI167 -30.049 2.081 -5.718 1.0036.17 C
ATOM9768CB THRI167 -30.790 1.972 -4.383 1.00 36.87C
ATOM9769OGl THRU67 -32.186 1.705 -4.654 1.00 36.49O
ATOM9770CG2 THRI 167-30.607 3.274 -3.573 1.00 34.62C
ATOM9771C THRI 167-29.988 0.675 -6.285 1.00 35.93C
ATOM9772O THRI 167 -29.326 -0.190 -5.695 1.00 35.26O
ATOM9773N HIS 1168 -30.681 0.446 -7.410 1.00 34.91N
ATOM9774CA HIS 1 168-30.770 -0.898 -8.012 1.0034.44C
ATOM9775CB HIS 1 168-31.817 -0.935 -9.149 1.00 34.32C
ATOM9776CG HIS 1 168-32.224 -2.319 -9.544 1.00 36.14C
ATOM9777NDl HIS 1168 -31.362 -3.206-10.151 1.00 35.53N
ATOM9778CEl HIS 1 168-31.991 -4.346-10.374 1.00 38.87C
ATOM9779NE2 HIS 1168-33.230 -4.233 -9.928 1.0039.10N
ATOM9780CD2HISI168-33.405 -2.973 -9.413 1.00 37.86C
ATOM9781C HISI168-29.413 -1.350 -8.549 1.00 33.45C
ATOM9782O HISI168 -28.840 -0.684 -9.429 1.00 33.63O
ATOM9783N PROI 169-28.895 -2.482 -8.021 1.00 32.59N
ATOM9784CA PROI169 -27.605 -3.022 -8.400 1.0031.58C
ATOM9785CB PRO I] 69-27.581 -4.376 -7.684 1.0031.45C
ATOM9786CG PRO 1 169-28.322 -4.076 -6.408 1.00 32.57C
ATOM9787CD PROI169 -29.505 -3.298 -6.951 1.00 32.50C
ATOM9788C PROI 169 -27.384 -3.166 -9.901 1.0031.25C
ATOM9789O PRO 1 169 -26.276 -2.863 -10.389 1.00 30.05O
ATOM9790N ILEI 170-28.403 -3.617-10.640 1.00 30.27N
ATOM9791CA ILEI 170 -28.257 -3.642 -12.083 1.00 29.54C
ATOM9792CB ILEI170 -29.399 -4.383-12.816 1.00 29.62C
ATOM9793CGl ILEI 170-29.421 -5.846-12.356 1.0030.39C
ATOM9794CDl ILEI 170 -30.586 -6.725-12.855 1.0030.14C
ATOM9795CG2ILE1 170-29.199 -4.252-14.319 1.0027.78C
ATOM9796C ILEI 170-28.012 -2.241 -12.652 1.00 29.30C
ATOM9797O ILEI 170-27.083 -2.059-13.458 1.00 29.25O
ATOM9798N ARGI171 -28.813 -1.257-12.224 1.0028.99N
ATOM9799CA ARGI171 -28.657 0.156-12.657 1.00 28.47C
ATOM9800CB ARGI171 -29.816 1.023-12.105 1.0029.42C
ATOM9801CG ARGI171 -29.647 2.534-12.356 1.00 28.21C
ATOM9802CD ARGI171 -30.881 3.342-12.051 1.00 26.61C
ATOM9803NE ARGI 171 -30.601 4.755-12.284 1.00 25.09N[0464]ATOM9804CZ ARGI171 -31.3785.783-11.9051.00 29.94C
ATOM9805NH1ARGI171-32.5185.582-11.2751.0028.83N
ATOM9806NH2ARGI171 -31.0327.039-12.1881.00 30.90N
ATOM9807C ARGI 171 -27.3090.785 -12.2421.0028.92C
ATOM9808O ARGI171 -26.6911.534-13.0121.0027.80O
ATOM9809N LEUI172 -26.8870.507-11.0021.0029.75N
ATOM9810CA LEUI 172-25.5400.892-10.5091.0029.77C ATOM9811CB LEUI172 -25.4120.581 -9.0151.0029.55C
ATOM9812CG LEUI 172-26.2471.496 -8.092 1.0029.36C
ATOM9813CDl LEUI 172-26.1351.094 -6.6181.0027.51C
ATOM9814CD2 LEUI 172-25.8462.924 -8.2991.0027.02C
ATOM9815C LEUI 172-24.4030.230-11.2961.00 30.50C
ATOM9816O LEUI 172-23.3700.857-11.5291.0031.24O
ATOM9817N GLYI 173 -24.605-1.022-11.7261.00 30.83N
ATOM9818CA GLYI 173 -23.593-1.756-12.5001.0031.06C
ATOM9819C GLYI 173 -23.444-1.297-13.9411.0031.04C
ATOM9820O GLYI 173 -22.353-1.377-14.5111.0031.00O
ATOM9821N LEUI174-24.538-0.816-14.5271.00 30.29N
ATOM9822CA LEUI 174-24.475-0.126-15.8101.0029.92C
ATOM9823CB LEUI 174-25.8790.118-16.3591.0029.45C
ATOM9824CG LEUI 174-25.8511.001 -17.6111.0029.37C
ATOM9825CDl LEUI 174-25.5840.213-18.8551.0026.10C
ATOM9826CD2 LEUI174-27.1251.816-17.7381.00 31.19C
ATOM9827C LEUI 174 -23.7381.212-15.7531.0029.53C
ATOM9828O LEUI174-22.9771.564-16.6451.00 30.33O
ATOM9829N ALAI 175 -24.0221.998-14.7411.00 28.94N
ATOM9830CA ALAI 175 -23.3543.287-14.5911.0029.15C
ATOM9831CB ALAI 175 -23.9634.056-13.4201.00 29.34C
ATOM9832C ALAI 175 -21.8503.075-14.3941.00 28.28C
ATOM9833O ALAI 175 -21.0393.769-15.0021.00 29.14O
ATOM9834N LEUI 176-21.5022.085 -13.5771.0027.97N
ATOM9835CA LEUI 176-20.1001.670-13.3791.0028.22C
ATOM9836CB LEUI 176-19.9520.592-12.2841.0027.04C
ATOM9837CG LEUI 176-18.5620.099-11.8391.0027.42C
ATOM9838CDl LEUI 176-17.6581.222-11.3091.0025.91C
ATOM9839CD2 LEU1 176-18.622-1.011 -10.7851.0026.67C
ATOM9840C LEUI 176-19.4781.227-14.7031.00 28.21C
ATOM9841O LEUI 176-18.4151.706-15.0801.0028.70O
ATOM9842N ASNI 177-20.1380.328-15.4231.00 28.16N
ATOM9843CA ASNI177-19.542-0.158-16.6471.0027.58C
ATOM9844CB ASNI 177-20.230-1.420-17.1211.0028.12C
ATOM9845CG ASNI177-19.688-2.647 -16.4391.0027.68C
ATOM9846ODl ASNI 177-19.087-2.552-15.3731.00 24.05O
ATOM9847ND2 ASNI 177-19.931-3.820-17.0301.00 26.29N
[0465]
[0468]ATOM9980CA CYS1 193-16.49410.956-13.583 1.00 33.31CATOM9981CB CYS1193-15.43712.010-13.214 1.00 33.84C
ATOM9982SG CYSI193-13.84211.267-12.931 1.00 35.24S
ATOM9983C CYS1193-17.87911.568-13.459 1.0031.81C
ATOM9984O CYS1 193-18.52911.377-12.449 1.0031.45O
ATOM9985N ASNI194-18.31112.328-14.454 1.0031.29N
ATOM9986CA ASNI194-19.67512.884-14.438 1.00 32.29C
ATOM9987CB ASN1194-19.97513.786-15.662 1.00 32.32C
ATOM9988CG ASNI 194-19.04915.009-15.770 1.00 35.56C
ATOM9989ODl ASNI194-19.01615.664-16.824 1.0041.61O
ATOM9990ND2 ASNI 194-18.30315.334-14.693 1.00 36.83N
ATOM9991C ASNI 194-20.72211.769-14.347 1.00 31.50C
ATOM9992O ASNI 194-21.65711.837-13.546 1.0031.85O
ATOM9993N LEUI195 -20.53910.736-15.154 1.0031.32N
ATOM9994CA LEUI 195 -21.5069.637-15.239 1.00 30.46C
ATOM9995CB LEUI 195 -21.1678.703 -16.399 1.0029.93C
ATOM9996CG LEUI195 -22.3457.858 -16.956 1.0029.31C
ATOM9997CDl LEUI195 -22.1467.622-18.415 1.00 28.93C
ATOM9998CD2 LEU1 195-22.4926.554-16.252 1.0025.07C
ATOM9999C LEUI 195-21.5398.872 -13.924 1.0030.47C
ATOM10000O LEUI195 -22.6178.651 -13.360 1.00 30.24O
ATOM10001N ALAI 196 -20.3598.524-13.408 1.00 30.13N
ATOM10002CA ALAI 196 -20.2687.747-12.166 1.00 29.91C
ATOM10003CB ALAI 196-18.8437.205-11.975 1.0028.94C
ATOM10004C ALAI 196 -20.7088.552-10.931 1.00 30.08C
ATOM10005O ALAI 196 -21.3848.031 -10.013 1.00 28.89O
ATOM10006N LYSI 197-20.2949.817 -10.902 1.00 30.92N
ATOM10007CA LYSI197-20.62910.692 -9.773 1.00 31.51C
ATOM10008CB LYSI 197-19.87512.025 -9.832 1.00 31.11C
ATOM10009CG LYSI 197-20.17912.921 -8.636 1.00 30.26C
ATOM10010CD LYSI 197-19.58812.296 -7.337 1.00 32.62C
ATOM10011CE LYS1197 -20.04213.034 -6.095 1.0032.31C
ATOM10012NZ LYSI 197-20.18614.505 -6.333 1.00 32.43N
ATOM10013C LYSI 197-22.12610.948 -9.699 1.0031.40C
ATOM10014O LYS1197-22.70610.916 -8.633 1.0031.35O
ATOM10015N GLNI198 -22.74411.207-10.842 1.00 32.26N
ATOM10016CA GLNI198 -24.199 11.367-10.886 1.00 32.46C
ATOM10017CB GLN1 198-24.65111.767-12.268 1.00 32.93C
ATOM10018CG GLNI198 -24.606 13.234-12.487 1.00 35.19C
ATOM10019CD GLNI198-25.61813.660-13.524 1.00 39.07C
ATOM10020OEl GLNI198 -25.24114.008 -14.637 1.00 40.11O
ATOM10021NE2 GLN1198-26.91613.625-13.167 1.00 39.17N
ATOM10022C GLNI198 -24.97410.131-10.447 1.0032.14C
ATOM10023O GLNI198 -25.96410.246 -9.730 1.0031.90O
[0469]·ATOM10068C ILE1204-28.0968.892-1.484 1.00 37.32C
ATOM10069O ILE1204-28.3998.792-0.285 1.00 36.99O
ATOM10070N ALAI 205 -28.8779.489-2.396 1.00 39.23N
ATOM10071CA ALAI 205 -30.13110.146-2.053 1.00 40.64C
ATOM10072CB ALAI 205 -30.70210.908-3.253 1.00 39.86C
ATOM10073C ALA 1205 -31.1409.146-1.474 1.0041.66C
ATOM10074O ALA 1205 -31.9369.506-0.598 1.0042.23O
ATOM10075N GLU1206-31.0587.886-1.904 1.0042.20N
ATOM10076CA GLU1206 -32.0216.871-1.469 1.0042.47C
ATOM10077CB GLU1206 -32.6886.258-2.688 1.00 42.52C
ATOM10078CG GLU1206 -33.3737.269-3.568 1.0043.10C
ATOM10079CD GLU1206 -34.4066.612-4.486 L00 47.33C
ATOM10080OEl GLU1206-34.6855.396-4.319 1.0046.62O
ATOM10081OE2 GLU1206-34.9267.310-5.387 1.0048.57O
ATOM10082C GLU1206 -31.4875.759-0.554 1.00 42.70C
ATOM10083O GLU1206-32.2835.0470.067 1.0043.36O
ATOM10084N LEU1207 -30.1625.623-0.464 1.0042.42N
ATOM10085CA LEU1207 -29.4984.541 0.277 1.00 42.61C
ATOM10086CB LEU1207 -27.9744.787 0.317 1.0042.14C
ATOM10087CG LEU1207-26.9263.679 0.041 1.0041.45C
ATOM10088CDl LEU1207-27.4312.2660.250 1.00 37.46C
ATOM10089CD2 LEU1207-25.5683.9060.816 1.0041.94C
ATOM10090C LEU1207 -30.0194.2261.706 1.0043.35C
ATOM10091O LEU1207-30.1223.0562.097 1.0043.30O
ATOM10092N ASP 1208 -30.3505.2602.464 1.0044.31N
ATOM10093CA ASP 1208 -30.7395.1253.862 1.0045.85C
ATOM10094CB ASP 1208 -30.6466.4964.531 1.0045.93C
ATOM10095CG ASP 1208 -30.7906.4296.045 1.0048.04C
ATOM10096ODl ASPI208 -31.4767.3036.620 1.0049.25O
ATOM10097OD2 ASP 1208-30.2205.5056.665 1.00 50.84O
ATOM10098C ASP 1208 -32.1484.5214.074 1.0047.10C
ATOM10099O ASP 1208 -32.5414.2235.213 1.0047.43O
ATOM10100N THR1209 -32.8864.3272.974 1.0047.90N
ATOM10101CA THR1209 -34.2413.756 2.980 1.00 48.33C
ATOM10102CB THRI209-35.1634.524 1.993 1.0048.48C
ATOM10103OGl THR1209 -34.7974.1940.636 1.00 46.48O
ATOM10104CG2 THRI209-35.0846.0642.251 1.0047.01C
ATOM10105C THR1209-34.3252.2532.623 1.0049.22C
ATOM10106O THR1209 -35.4221.7042.512 1.0049.51O
ATOM10107N LEUI210-33.1831.5952.452 1.00 50.04N
ATOM10108CA LEU1210-33.1470.202 2.018 1.0050.99C
ATOM10109CB LEU1210-31.975-0.016 1.063 1.00 50.78C
ATOM10110CG LEUI210-31.8920.870-0.182 1.00 50.85C
ATOM10111CDl LEU1210-30.5910.584-0.869 1.00 49.72C
[0471]ATOM10112CD2 LEU1210-33.072 0.643-1.1401.00 50.84CATOM10113C LEU1210-33.125 -0.8603.1491.0052.15C
ATOM10114O LEU1210-33.937 -1.8083.1411.0051.77O
ATOM10115N GLYI211-32.190 -0.7254.0941.00 53.17N
ATOM10116CA GLYI211 -31.979 -1.7415.1631.00 54.49C
ATOM10117C GLY1211-32.057 -3.2204.7601.00 55.26C
ATOM10118O GLY1211-32.747 -3.5843.8031.00 54.60O
ATOM10119N GLU1212-31.370 -4.0605.5381.00 56.32N·
ATOM10120CA GLU1212-31.179 -5.5135.2931.00 57.31C
ATOM10121CB GLUI212-32.455 -6.3815.5521.00 57.70C
ATOM10122CG GLU1212-33.752 -6.0274.7861.0058.70C
ATOM10123CD GLUI212-34.016 -6.8853.5381.00 59.82C
ATOM10124OEl GLU1212-34.276 -8.1093.6901.00 59.00O
ATOM10125OE2 GLU1212-34.006 -6.3152.4101.00 59.60O
ATOM10126C GLU1212-30.462 -5.8753.9831.00 57.19C
ATOM10127O GLU1212-29.487 -5.2113.5981.00 56.86O
ATOM10128N GLU T 213-30.938 -6.9523.3531.00 57.01N
ATOM10129CA GLUI213-30.470 -7.4602.0581.00 56.86C
ATOM10130CB GLU1213-31.450 -8.5391.5511.00 56.63C
ATOM10131CG GLUI213-31.201 -9.0370.1361.00 56.74C
ATOM10132CD GLU1213-31.717-10.462-0.1081.00 57.14C
ATOM10133OEl GLU1213 -32.643 -10.9320.6021.00 56.03O
ATOM10134OE2 GLU1213-31.181-11.115-1.0291.00 57.33O
ATOM10135C GLUI213-30.266 -6.3780.9881.00 56.39C
ATOM10136O GLU1213-29.221 -6.3550.3341.00 56.84O
ATOM10137N SERI 214-31.243 -5.4850.8271.00 55.49N
ATOM10138CA SERI 214-31.235 -4.513-0.2711.00 54.84C
ATOM10139CB SERI 214-32.598 -3.843-0.3961.00 54.66C
ATOM10140OG SER1214-32.770 -3.339-1.7041.00 54.52O
ATOM10141C SERI 214-30.100 -3.473-0.1631.00 54.62C
ATOM10142O SERI 214-29.457 -3.125-1.1611.00 54.44O
ATOM10143N TYRI215-29.868 -2.9941.0561.00 54.07N
ATOM10144CA TYRI215-28.703 -2.1911.3671.00 53.85C
ATOM10145CB TYRI215-28.657 -1.8962.8671.00 53.38C
ATOM10146CG TYRI215-27.364 -1.2733.3261.00 52.18C
ATOM10147CDl TYRI215-27.046 0.0362.9801.0051.83C
ATOM10148CEl TYRI215-25.854 0.6173.3881.0051.55C
ATOM10149CZ TYRI215-24.971 -0.1024.1631.0051.55C
ATOM10150OH TYRI215-23.799 0.500 4.5541.0051.78O
ATOM10151CE2 TYRI215-25.261 -1.4034.5331.00 50.43C
ATOM10152CD2 TYR1215-26.460 -1.9854.1041.00 51.50C
ATOM10153C TYRI215-27.416 -2.9070.9481.00 54.43C
ATOM10154O TYRI215-26.580 -2.3380.2411.00 54.32O
ATOM10155N LYS1216 -27.272 -4.1591.3921.00 54.87N[0472]ATOM10156CA LYS1216-26.057-4.9401.168 1.00 54.92C
ATOM10157CB LYS1216-26.116-6.2911.908 1.00 55.83C
ATOM10158CG LYS1216-26.940-6.3433.226 1.00 57.41C
ATOM10159CD LYS1216-26.430-5.3964.356 1.00 61.18C
ATOM10160CE LYS1216-27.375-5.4205.600 1.00 60.13C
ATOM10161NZ LYS1216-27.603-4.0936.298 1.00 61.49N
ATOM10162C LYS1216-25.769-5.125-0.338 1.00 54.41C
ATOM10163O LYS1216-24.646-4.841-0.783 1.0053.54O ATOM10164N ASPI 217-26.785-5.555-1.111 1.00 53.58N
ATOM10165CA ASP 1217-26.633-5.768-2.561 1.00 53.30C
ATOM10166CB ASPI217-27.960-6.099-3.276 1.00 53.53C
ATOM10167CG ASPI217-28.767-7.199-2.603 1.00 53.83C
ATOM10168ODl ASPI217-28.182-8.136-2.012 1.00 54.80O
ATOM10169OD2ASPI217-30.016-7.128-2.694 1.0054.20O
ATOM10170C ASPI217-26.040-4.540-3.232 1.00 52.81C
ATOM10171O ASPI217-25.020-4.626-3.896 1.00 53.16O
ATOM10172N SERI218-26.677-3.389-3.048 1.0052.48N
ATOM10173CA SERI 218-26.285-2.175-3.783 1.0051.55C
ATOM10174CB SERI 218-27.471-1.222-3.907 1.0051.83C
ATOM10175OG SER1218-27.937-0.811-2.644 1.0051.23O
ATOM10176C SERI 218-25.059-1.420-3.259 1.00 50.50C
ATOM10177O SERI 218-24.463-0.660-4.010 1.00 50.03O
ATOM10178N THRI219-24.705-1.614-1.985 1.00 49.86N
ATOM10179CA THRI219-23.546 -0.942 -1.343 1.0049.24C
ATOM10180CB THRI219-23.463-1.239 0.188 1.0049.55C
ATOM10181OGl THRI219-24.717-0.9380.813 1.00 51.14O
ATOM10182CG2 THRI219-22.370-0.4100.865 1.00 50.31C
ATOM10183C THRI219-22.208-1.345-1.958 1.0048.29C
ATOM10184O THRI219-21.284-0.531-2.023 1.0048.46O
ATOM10185N LEUI 220-22.101-2.600-2.391 1.0046.94N
ATOM10186CA LEU1220 -20.862 -3.106 -2.954 1.0045.71C
ATOM10187CB LEU1220-20.884-4.631-3.090 1.0046.46C
ATOM10188CG LEU1220 -19.839 -5.272 -4.019 1.0047.45C
ATOM10189CDl LEU1220-20.249-6.697-4.351 1.0047.96C
ATOM10190CD2 LEU1220-18.373-5.176-3.488 1.00 50.09C
ATOM10191C LEU1220-20.521-2.436-4.278 1.0044.53C
ATOM10192O LEU1220-19.357-2.137-4.512 1.0044.78O
ATOM10193N ILE1221 -21.522-2.172-5.115 1.0042.39N
ATOM10194CA ILE1221 -21.295-1.495-6.406 1.0041.23C
ATOM10195CB ILEI221 -22.478-1.666-7.393 1.00 40.88C
ATOM10196CGl ILE1221 -22.809-3.156-7.551 1.0041.02C
ATOM10197CDl ILE1221-23.888-3.427-8.550 1.00 43.08C
ATOM10198CG2ILE1221 -22.133-1.019-8.740 1.00 38.74C
ATOM10199C ILE1221 -20.986-0.012-6.266 1.0040.75C
[0473]ATOM10200O ILE1221-20.3260.583 -7.1191.0040.38OATOM10201N MET 1222 -21.4710.579 -5.1861.00 40.27N
ATOM10202CA MET 1222 -21.2261.964 -4.9161.0040.57C
ATOM10203CB METI222-22.3002.463 -3.9831.0040.60C
ATOM10204CG MET 1222 -23.5522.906 -4.7081.0041.77C
ATOM10205SD MET 1222 -24.7763.180 -3.4381.00 46.95S
ATOM10206CE MET 1222 -24.0084.540 -2.5231.0045.46C ATOM10207C METI222-19.8412.212 -4.3261.00 38.26C
ATOM10208O MET 1222-19.2483.241 -4.5691.00 38.44O
ATOM10209N GLNI223-19.3481.272 -3.5451.00 36.43N
ATOM10210CA GLN1223-17.9511.249 -3.1341.0035.57C
ATOM10211CB GLN1223-17.691-0.019 -2.3711.00 35.47C
ATOM10212CG GLN1223-18.470-0.101 -1.1141.00 37.65C
ATOM10213CD GLNI223-18.107-1.325 -0.3381.0041.59C
ATOM10214OEl GLNI223-18.045-1.293 0.8901.00 44.73O
ATOM10215NE2 GLNI223-17.852-2.419 -1.0461.0042.36N
ATOM10216C GLNI223-16.9921.277 -4.3111.00 34.68C
ATOM10217O GLNI223-15.9001.872 -4.2471.00 34.50O
ATOM10218N LEU1224-17.4120.628 -5.3901.00 33.89N
ATOM10219CA LEU1224-16.5960.503 -6.5811.00 33.10C
ATOM10220CB LEU1224-16.987-0.741 -7.3971.00 33.12C
ATOM10221CG LEU1224-17.084-2.120 -6.7261.00 32.09C
ATOM10222CDl LEU1224-17.754-3.166 -7.6271.0028.99C
ATOM10223CD2 LEU1224-15.724-2.590 -6.3221.0032.33C
ATOM10224C LEUI224-16.7121.762 -7.4131.0032.61C
ATOM10225O LEU1224-15.7202.172 -8.0031.0033.01O
ATOM10226N LEUI225-17.9002.383 -7.4741.0032.32N
ATOM10227CA LEUI225-18.0073.727 -8.1021.00 32.06C
ATOM10228CB LEUI225-19.4354.250 -8.1621.0031.70C
ATOM10229CG LEU1225 -20.5103.584 -9.0561.0031.87C
ATOM10230CDl LEU1225-21.9033.824 -8.4651.0030.90C
ATOM10231CD2 LEU1225-20.4084.077 -10.5031.0027.75C
ATOM10232C LEUI225-17.1494.711 -7.2931.00 32.32C
ATOM10233O LEU1225-16.3745.491 -7.8461.0032.36O
ATOM10234N ARGI 226-17.3014.660 -5.9731.00 32.01N
ATOM10235CA ARG1226-16.5715.552 -5.0831.00 32.27C
ATOM10236CB ARG1226-16.9625.254 -3.6471.0031.49C
ATOM10237CG ARG1226-16.2506.091 -2.6401.00 32.40C
ATOM10238CD ARG1226-16.3345.445 -1.3021.00 30.77C
ATOM10239NE ARG1226-15.6634.165 -1.2911.00 30.42N
ATOM10240CZ ARGI226-15.7723.276 -0.3161.0031.50C
ATOM10241NHl ARG1226-16.5293.525 0.7381.00 33.58N
ATOM10242NH2ARGI226-15.1332.127 -0.4081.00 32.02N
ATOM10243C ARGI226-15.0545.448 -5.2801.00 32.42C
[0474]ATOM10244O ARG1226-14.3706.457 -5.455 1.00 32.48OATOM10245N ASPI227-14.5514.216 -5.294 1.00 33.41N
ATOM10246CA ASPI227-13.1113.947 -5.414 1.00 33.79C
ATOM10247CB ASPI227-12.7892.488 -5.108 1.00 34.40C
ATOM10248CG ASPI227-12.9522.154 -3.636 1.00 34.47C
ATOM10249ODl ASP 1227-13.2153.063 -2.815 1.00 34.58O
ATOM10250OD2ASPI227-12.8300.963 -3.320 1.00 37.06O·
ATOM10251C ASPI227-12.6214.265 -6.780 1.00 33.44C
ATOM10252O ASPI227-11.5404.787 -6.912 1.0033.33O
ATOM10253N ASNI228-13.4233.960 -7.802 1.00 33.50N
ATOM10254CA ASN1228-13.0954.402 -9.167 1.00 33.13 C
ATOM10255CB ASN1228-14.1313.953 -10.201 1.00 33.27C
ATOM10256CG ASNI228-13.8342.593-10.786 1.00 33.18C
ATOM10257ODl ASNI228-12.7742.029-10.562 1.0032.77O
ATOM10258ND2 ASNI228-14.7832.062-11.556 1.0029.40N
ATOM10259C ASNI228-12.9905.903 -9.238 1.00 32.94C
ATOM10260O ASNI228-12.0406.405 -9.841 1.00 32.41O
ATOM10261N LEUI 229-13.9836.598 -8.650 1.00 32.44N
ATOM10262CA LEU1229-14.0478.075 -8.671 1.00 32.79 C
ATOM10263CB LEU1229-15.3638.609 -8.095 1.00 32.74C
ATOM10264CG LEU1229-16.6168.670 -8.984 1.00 32.74 C
ATOM10265CDl LEU1229-17.8458.750 -8.097 1.00 33.59C
ATOM10266CD2 LEUI229-16.5909.836 -9.956 1.0031.10C
ATOM10267C LEU1229-12.9028.682 -7.879 1.0032.53C
ATOM10268O LEUI 229-12.3559.705 -8.257 1.00 32.36O
ATOM10269N THRI230-12.5848.063 -6.756 1.00 32.84N
ATOM10270CA THRI230-11.4268.468 -5.965 1.00 33.62 C
ATOM10271CB THRI230-11.3407.658 -4.678 1.0033.17C
ATOM10272OGl THRI 230-12.5377.878 -3.932 1.0031.05O
ATOM10273CG2 THR1230-10.1018.074 -3.818 1.00 33.42C
ATOM10274C THRI230-10.1428.319 -6.785 1.0034.56C
ATOM10275O THR1230 -9.3179.229 -6.829 1.00 35.18 O
ATOM10276N LEU1231-10.0027.184 -7.460 1.0035.76N
ATOM10277CA LEU1231 -8.8396.909 -8.283 1.0035.93 C
ATOM10278CB LEU1231 -8.9315.484 -8.828 1.00 35.94 C
ATOM10279CG LEU1231 -7.9395.138 -9.944 1.0036.65 C
ATOM10280CDl LEU1231 -6.5085.023 -9.326 1.00 33.95 C
ATOM10281CD2LEUI231 -8.3703.884-10.628 1.00 33.24C
ATOM10282C LEU1231 -8.7047.946 -9.403 1.00 36.81C
ATOM10283O LEU1231 -7.6478.570 -9.585 1.00 36.36 O
ATOM10284N TRP1232 -9.8018.149-10.120 1.0037.20N
ATOM10285CA TRP1232 -9.8429.024-11.269 1.00 38.04C
ATOM10286CB TRPI232-11.2038.875-11.982 1.00 37.47C
ATOM10287CG TRPI232-11.3537.527-12.650 1.00 36.55C
[0475]ATOM10288CDl TRPI232-10.3346.666-12.951 1.00 36.79CATOM10289NEl TRPI232-10.8185.550-13.577 1.0035.60N
ATOM10290CE2 TRPI232-12.1765.669-13.726 1.00 36.02C
ATOM10291CD2 TRPI232-12.5566.914-13.166 1.0036.15C
ATOM10292CE3 TRPI232-13.9177.274-13.178 1.0034.40C
ATOM10293CZ3 TRPI232-14.8466.385 -13.752 1.0036.17C
ATOM10294CH2 TRPI232-14.4295.162-14.316 1.00 35.55C
ATOM10295CZ2TRPI232-13.1044.785 -14.309 1.00 34.99C
ATOM10296C TRP1232 -9.53610.478-10.909 1.00 39.90C
ATOM10297O TRPI232 -9.04111.227-11.744 1.00 39.92O
ATOM10298N THR1233 -9.80210.860 -9.655 1.0041.92N
ATOM10299CA THRI233 -9.66512.246 -9.187 1.0043.36C
ATOM10300CB THRI233-10.97712.716 -8.489 1.0043.49C
ATOM10301OGl THR1233-12.06712.679 -9.425 1.0044.14O
ATOM10302CG2 THR1233-10.85114.150 -7.953 1.0044.94C
ATOM10303C THR1233 -8.45612.412 -8.237 1.0044.23C
ATOM10304O THR1233 -8.38613.370 -7.443 1.0043.41O
ATOM10305N SERI 234 -7.49911.492 -8.368 1.0045.49N
ATOM10306CA SER1234 -6.45711.275 -7.367 1.0046.57C
ATOM10307CB SER1234 -6.0889.783 -7.290 1.0046.35C
ATOM10308OG SER1234 -5.6539.310 -8.539 1.0045.26O
ATOM10309C SERI 234 -5.18512.126 -7.493 1.00 47.79C
ATOM10310O SERI 234 -4.36212.130 -6.572 1.0047.48O
ATOM10311N ASP 1235 -5.00712.812 -8.618 1.0048.70N
ATOM10312CA ASPI235 -3.96713.847 -8.740 1.00 50.30C
ATOM10313CB ASP 1235 -2.56613.412 -8.196 1.00 50.23C
ATOM10314CG ASP 1235 -2.24214.006 -6.771 1.0051.46C
ATOM10315ODl ASPI235 -1.40214.938 -6.649 1.00 50.68O
ATOM10316OD2 ASPI235 -2.82113.538 -5.763 1.00 49.79O
ATOM10317C ASP 1235 -3.90614.296-10.201 1.00 51.01C
ATOM10318O ASP 1235 -4.56315.278-10.581 1.0051.15O
ATOM10319OXTASPI235 -3.21613.677-11.034 1.00 52.07O TER
ATOM10320N ALAJ187 -6.9930.627 -6.042 1.0064.89N
ATOM10321CA ALAJ187 -6.5251.853 -6.739 1.00 64.92C
ATOM10322CB ALAJ187 -7.1523.102 -6.112 1.00 64.95C
ATOM10323C ALAJ187 -4.9931.891 -6.659 1.00 64.88C
ATOM10324O ALAJ187 -4.4532.028 -5.550 1.0065.27O
ATOM10325N ALAJ188 -4.2731.793 -7.790 1.00 63.98N
ATOM10326CA ALAJ188 -4.7741.980 -9.174 1.00 63.04C
ATOM10327CB ALAJ188 -3.5742.212-10.151 1.0063.09C
ATOM10328C ALAJ188 -5.7680.955 -9.774 1.00 62.21C
ATOM10329O ALAJ188 -5.9990.956-10.995 1.00 62.31O
ATOM10330N ARGJ189 -6.3620.102 -8.932 1.00 60.80N
[0476]
[0477]ATOM10375CD PRO J194-19.602 -5.988 -9.432 1.00 37.97 CATOM10376C PRO J 194-20.191 -8.573-11.494 1.00 39.72 C
ATOM10377O PRO J 194-20.454 -8.005 -12.543 1.0040.43 O
ATOM10378N PHE J195-20.901 -9.597-11.062 1.00 40.62 N
ATOM10379CA PHE J195 -22.059 -10.104 -11.839 1.0040.68 C
ATOM10380CB PHEJ195 -23.411 -9.549-11.350 1.0040.80 C
ATOM10381CG PHE J195-23.777 -8.142-11.838 1.0041.35 C
ATOM10382CDl PHE J 195-24.352 -7.948-13.102 1.00 40.93 C
ATOM10383CEl PHEJ195 -24.752 -6.680-13.521 1.0040.81 C
ATOM10384CZ PHEJ195 -24.601 -5.582 -12.663 1.00 40.25 C
ATOM10385CE2 PHE J195-24.051 -5.769-11.391 1.00 39.86 C
ATOM10386CD2PHE J195-23.670 -7.042 -10.978 1.00 39.73 C
ATOM10387C PHEJ195 -21.896 -10.115 -13.372 1.0040.92 C
ATOM10388O PHE J195-21.826 -9.094-14.079 1.0040.44 O
ATOM10389OXTPHE J 195 -21.777 -11.215 -13.923 1.0041.14 OTER
ATOM10390N GLYK 5 15.965 -9.369 34.303 1.00 54.53 N
ATOM10391CA GLYK 5 14.921 -9.324 35.377 1.00 55.77 C
ATOM10392C GLYK 5 13.763 -8.377 35.080 1.00 56.07 C
ATOM10393O GLYK 5 13.939 -7.398 34.344 1.00 56.68 O
ATOM10394N ARGK 6 12.582 -8.640 35.651 1.00 55.89 N
ATOM10395CA ARGK 6 11.416 -7.801 35.355 1.00 55.77 C
ATOM10396CB ARGK 6 11.052 -7.923 33.863 1.00 56.09 C
ATOM10397CG ARGK 6 10.661 -6.602 33.191 1.0057.74 C
ATOM10398CD ARGK 6 11.694 -6.147 32.145 1.0061.89 C
ATOM10399NE ARGK 6 11.174 -6.265 30.771 1.00 64.38 N
ATOM10400CZ ARGK 6 11.839 -5.960 29.647 1.00 65.79 C
ATOM10401NHl ARGK 6 13.108 -5.511 29.678 1.00 66.68 N
ATOM10402NH2ARGK 6 11.227 -6.114 28.473 1.00 64.59 N
ATOM10403C ARGK 6 10.129 -8.033 36.169 1.00 55.41 C
ATOM10404O ARGK 6 9.797 -9.165 36.561 1.00 56.23 O
ATOM10405N ALAK 7 9.446 -6.916 36.442 1.00 54.24 N
ATOM10406CA ALAK 7 7.976 -6.790 36.330 1.00 52.68 C
ATOM10407CB ALAK 7 7.415 -7.622 35.102 1.00 53.16 C
ATOM10408C ALAK 7 7.094 -6.979 37.547 1.0051.49 C
ATOM10409O ALAK 7 6.257 -6.122 37.833 1.0051.55 O
ATOM10410N ARGK 8 7.256 -8.106 38.240 1.0049.98 N
ATOM10411CA ARGK 8 6.260 -8.563 39.193 1.0047.55 C
ATOM10412CB ARGK 8 6.027 -7.471 40.267 1.0047.53 C
ATOM10413CG ARGK 8 5.195 -7.868 41.477 1.0047.32 C
ATOM10414CD ARGK 8 3.713 -7.570 41.269 1.0048.71 C
ATOM10415NE ARGK 8 3.172 -8.390 40.186 1.0047.57 N
ATOM10416CZ ARGK 8 1.987 -8.243 39.587 1.0048.43 C
ATOM10417NHl ARGK 8 1.658 -9.074 38.584 1.0045.68 N
[0478]ATOM10418NH2ARGK 81.141 -7.288 39.967 1.0048.48 NATOM10419C ARGK84.959 -8.986 38.404 1.0046.31 C
ATOM10420O ARGK83.910 -8.339 38.507 1.0046.92 O
ATOM10421N ASPK95.017-10.051 37.601 1.0043.52N
ATOM10422CA ASPK93.829-10.463 36.846 1.0040.13C
ATOM10423CB ASPK94.167-10.619 35.364 1.00 41.06C
ATOM10424CG ASPK95.267-11.595 35.114 1.0040.70C ATOM10425ODl ASP K95.070-12.804 35.348 1.00 39.89O
ATOM10426OD2ASPK96.327-11.141 34.642 1.00 44.79O
ATOM10427C ASPK93.118-11.703 37.418 1.00 37.89C
ATOM10428O ASPK93.415 -12.097 38.566 1.00 37.49O
ATOM10429N PROK102.148-12.304 36.651 1.0035.41N
ATOM10430CA PROK101.500-13.543 37.098 1.00 33.36 C
ATOM10431CB PROK100.729-14.031 35.860 1.00 33.69C
ATOM10432CG PROK100.516-12.844 35.035 1.00 34.96 C
ATOM10433CD PROK101.585-11.819 35.376 1.00 34.58C
ATOM10434C PROK102.451 -14.648 37.581 1.0032.18C
ATOM10435O PROK102.072 -15.392 38.475 1.00 32.53O
ATOM10436N LEUKU3.653-14.781 37.009 1.00 30.52N
ATOM10437CA LEUK114.620-15.771 37.518 1.0029.85C
ATOM10438CB LEUK115.803 -15.962 36.573 1.0028.97C
ATOM10439CG LEUK115.507-16.395 35.147 1.0028.76C
ATOM10440CDl LEU K116.775-16.675 34.452 1.00 24.49C
ATOM10441CD2LEUK114.526-17.614 35.073 1.00 27.64C
ATOM10442C LEUK115.134-15.451 38.942 1.00 30.02C
ATOM10443O LEUK115.357-16.378 39.718 1.00 29.41O
ATOM10444N VALK125.308-14.167 39.287 1.00 30.03N
ATOM10445CA VALK125.673 -13.813 40.694 1.0030.58C
ATOM10446CB VALK126.635 -12.558 40.851 1.0031.05C
ATOM10447CGl VALK126.914-11.903 39.560 1.0029.86C
ATOM10448CG2VALK126.143-11.551 41.928 1.0031.07C
ATOM10449C VALK124.456-13.765 41.642 1.00 30.88C
ATOM10450O VALK124.555-14.177 42.794 1.0031.02O
ATOM10451N VALK133.306-13.323 41.139 1.0031.12N
ATOM10452CA VALK132.052-13.464 41.884 1.0031.47C
ATOM10453CB VALK130.830 -12.942 41.074 1.00 32.02C
ATOM10454CGl VALK13-0.559-13.316 41.729 1.00 31.74C
ATOM10455CG2VALK130.953-11.424 40.819 1.0031.38C
ATOM10456C VALK131.910-14.954 42.231 1.0031.84C
ATOM10457O VALK131.618-15.313 43.397 1.0031.97O
ATOM10458N GLYK142.150-15.809 41.227 1.0031.05N
ATOM10459CA GLYK142.027-17.264 41.378 1.0029.33C
ATOM10460C GLYK143.170-17.866 42.165 1.0028.19C
ATOM10461O GLYK143.195-19.075 42.411 1.0026.49O
[0479]ATOM 10462N ARGK154.134-17.020 42.5531.00 28.61NATOM 10463CA ARGK155.306-17.448 43.348 1.00 28.40C
ATOM 10464CB ARGK154.902-17.945 44.745 1.0028.37C
ATOM 10465CG ARGK154.222-16.884 45.614 1.0031.09C
ATOM10466CD ARGK155.197-15.711 45.889 1.0041.49C
ATOM10467NE ARGK154.485 -14.438 46.079 1.0046.93N
ATOM 10468CZ ARGK155.017-13.223 45.929 1.0048.32C
ATOM10469NHl ARGK156.282-13.065 45.5581.0049.06N ATOM10470NH2ARGK154.264-12.153 46.1391.00 49.55N
ATOM10471C ARGK156.155-18.474 42.6031.0028.98C
ATOM10472O ARGK156.983-19.180 43.1751.00 30.35O
ATOM10473N VALK165.969-18.536 41.2931.00 29.90N
ATOM10474CA VALK166.803 -19.384 40.4691.00 29.55C
ATOM10475CB VALK166.234-19.535 39.0811.0029.46C
ATOM10476CGl VALK167.304-20.145 38.1521.0028.79C
ATOM10477CG2VALK164.949 -20.409 39.1381.00 29.19C
ATOM10478C VALK168.169-18.725 40.4131.0029.17C
ATOM10479O VALK169.170-19.374 40.6361.0029.42O
ATOM10480N VALK178.193 -17.438 40.0931.0029.79N
ATOM10481CA VALK179.404-16.616 40.2161.00 30.36C
ATOM10482CB VALK179.304-15.311 39.3631.00 30.24C
ATOM10483CGl VALK1710.403-14.322 39.7381.0028.71C
ATOM10484CG2VALK179.327-15.652 37.8471.0029.35C
ATOM10485C VALK179.502-16.314 41.7081.00 30.67C
ATOM10486O VALK178.796-15.446 42.2451.00 30.72O
ATOM10487N GLYK1810.333 -17.095 42.3781.00 31.10N
ATOM10488CA GLYK1810.416-17.066 43.842 1.0031.02C
ATOM10489C GLYK1810.790-18.442 44.3301.00 30.75C
ATOM10490O GLYK1811.893-18.644 44.8331.0031.38O
ATOM10491N ASPK199.901 -19.413 44.1271.00 29.71N
ATOM10492CA ASP K1910.169-20.794 44.5881.00 28.56C
ATOM10493CB ASPK198.846-21.555 44.8101.00 28.32C
ATOM10494CG ASPK197.899 -20.804 45.7081.0029.36C
ATOM10495ODl ASP K198.377-19.940 46.4941.00 26.71O
ATOM10496OD2ASPK196.673 -21.064 45.6291.00 27.92O
ATOM10497C ASPK1911.074-21.584 43.6501.0027.10C
ATOM10498O ASPK1911.715-22.563 44.0501.0027.34O
ATOM10499N VALK2011.133-21.160 42.3911.00 26.35N
ATOM10500CA VALK2011.774-21.986 41.3661.0023.88C
ATOM10501CB VALK2010.683 -22.624 40.4151.00 23.58C
ATOM10502CGl VALK2011.334-23.401 39.2931.0017.23C
ATOM10503CG2VALK209.748 -23.508 41.2021.0023.77C
ATOM10504C VALK2012.688-21.211 40.4601.00 23.63C
ATOM10505O VALK2013.707-21.741 40.0021.0023.62O
[0480]ATOM10506N LEUK 2112.266-19.997 40.130 1.00 24.63NATOM10507CA LEUK 2112.911 -19.186 39.089 1.0026.16C
ATOM10508CB LEUK 2111.946-18.947 37.914 1.0025.40C
ATOM10509CG LEUK 2111.439-20.160 37.103 1.0026.91C
ATOM10510CDl LEUK 2110.569-19.775 35.856 1.00 25.69C
ATOM10511CD2LEUK 2112.568 -21.156 36.707 1.0026.10C
ATOM10512C LEUK 2113.378 -17.847 39.676 1.0027.92C
ATOM10513O LEUK 2112.808-17.385 40.674 1.00 28.83O
ATOM10514N ASPK 2214.445 -17.263 39.112 1.00 29.46N
ATOM10515CA ASPK 2214.718-15.840 39.321 1.00 30.94C
ATOM10516CB ASPK 2216.203-15.489 39.166 1.0031.19C
ATOM10517CG ASPK 2217.054-16.051 40.278 1.00 32.84C
ATOM10518ODl ASPK 2218.148-16.586 39.999 1.00 34.44O
ATOM10519OD2ASPK 2216.609-15.972 41.437 1.0038.15O
ATOM10520C ASPK 2213.917-15.140 38.239 1.0031.50C
ATOM10521O ASPK 2213.398-15.799 37.344 1.00 31.91O
ATOM10522N ALAK 2313.783 -13.821 38.363 1.0031.44N
ATOM10523CA ALAK 2313.166-12.978 37.361 1.0031.55C
ATOM10524CB ALAK 2313.119-11.546 37.844 1.0031.28C
ATOM10525C ALAK 2313.935 -13.077 36.039 1.0031.73C
ATOM10526O ALAK 2315.160-13.214 36.040 1.0032.05O
ATOM10527N PHEK 2413.195-13.010 34.928 1.0031.30N
ATOM10528CA PHEK 2413.751-13.111 33.575 1.00 30.95C
ATOM10529CB PHFK 2413.803 -14.577 33.108 1.00 30.54C
ATOM10530CG PHEK 2412.435-15.217 32.945 1.0028.17C
ATOM10531CDl PHEK 2411.772-15.783 34.046 1.0028.64C
ATOM10532CEl PHEK 2410.500-16.381 33.897 1.0028.20C
ATOM10533CZ PHEK 249.898-16.413 32.625 1.0027.98C
ATOM10534CE2PHEK 2410.557-15.871 31.538 1.0025.87C
ATOM10535CD2PHEK 2411.827-15.270 31.702 1.0025.67C
ATOM10536C PHEK 2412.888-12.289 32.620 1.0031.05C
ATOM10537O PHEK 2411.825-11.808 33.001 1.0031.56O
ATOM10538N VALK 2513.349-12.111 31.381 1.00 30.92N
ATOM10539CA VALK 2512.554-11.410 30.384 1.00 30.39C
ATOM10540CB VALK 2513.330-10.242 29.695 1.00 30.88C
ATOM10541CGl VALK 2512.452 -9.574 28.645 1.00 30.07C
ATOM10542CG2VALK 2513.809 -9.172 30.734 1.0031.64C
ATOM10543C VALK 2512.033 -12.455 29.367 1.0029.55C
ATOM10544O VALK 2512.794-13.265 28.844 1.0029.76O
ATOM10545N ARGK 2610.739-12.465 29.110 1.0028.38N
ATOM10546CA ARGK 2610.198-13.493 28.188 1.0027.92C
ATOM10547CB ARGK 268.694-13.497 28.249 1.0026.72C
ATOM10548CG ARGK 268.087-14.098 29.490 1.0027.60C
ATOM10549CD ARGK 266.563 -13.809 29.426 1.0025.77C
[0481]
[0482]ATOM10594N VALK32 1.300-24.413 25.8861.0017.64NATOM10595CA VALK32 1.112-25.728 26.5081.0018.25C
ATOM10596CB VALK32 1.537 -25.694 27.9941.0017.90C
ATOM10597CGl VALK32 1.313-27.064 28.6141.0019.08C
ATOM10598CG2VALK32 3.033 -25.187 28.1821.0017.22C
ATOM10599C VALK32 -0.414-26.125 26.4171.0018.58C
ATOM10600O VALK32 -1.254-25.368 26.8481.0018.86O
ATOM10601N THRK33 -0.770 -27.272 25.8571.0018.59N
ATOM10602CA THRK 33 -2.234 -27.580 25.6291.0017.71C
ATOM10603CB THRK33 -2.683 -27.282 24.2031.0018.11C
ATOM10604OGl THRK33 -2.487 -25.896 23.8711.0018.08O
ATOM10605CG2THRK33 -4.231 -27.675 23.9141.00 17.56C
ATOM10606C THRK33 -2.516-29.061 25.9911.0018.15C
ATOM10607O THRK33 -1.862-29.976 25.4981.0018.82O
ATOM10608N TYRK34 -3.473 -29.280 26.8831.00 18.11N
ATOM10609CA TYRK34 -3.921 -30.614 27.1821.0019.20C
ATOM10610CB TYRK34 -4.153 -30.737 28.6841.0018.83C
ATOM10611CG TYRK34 -2.881 -30.925 29.4981.0020.29C
ATOM10612CDl TYRK34 -2.349-32.183 29.6981.0019.84C
ATOM10613CEl TYRK34 -1.218-32.359 30.4381.0019.86C
ATOM10614CZ TYRK34 -0.574-31.256 30.9841.0019.79C
ATOM10615OH TYRK 34 0.586-31.420 31.708 1.0019.82 O
ATOM10616CE2TYRK34 -1.067-29.999 30.7981.0020.15C
ATOM10617CD2TYRK34 -2.205 -29.827 30.0431.00 20.30C
ATOM10618C TYRK34 -5.243 -30.824 26.4091.00 18.09C
ATOM10619O TYRK34 -6.190-30.136 26.6431.00 18.14O
ATOM10620N GLYK35 -5.296-31.769 25.4861.00 20.06N
ATOM10621CA GLYK35 -6.490 -31.949 24.6011.0019.25C
ATOM10622C GLYK35 -6.688 -30.672 23.7961.0020.12C
ATOM10623O GLYK35 -5.949 -30.339 22.8811.00 18.43O
ATOM10624N SERK36 -7.689 -29.910 24.1821.0022.63N
ATOM10625CA SERK36 -7.972 -28.695 23.4541.0024.65C
ATOM10626CB SERK36 -9.327-28.812 22.7231.00 24.73C
ATOM10627OG SERK36-10.344-28.435 23.6201.00 25.45O
ATOM10628C SERK36 -7.996 -27.522 24.3821.0024.18C
ATOM10629O SERK36 -8.383 -26.442 23.9611.0024.98O
ATOM10630N LYSK37 -7.575 -27.738 25.6281.0024.31N
ATOM10631CA LYSK37 -7.495 -26.681 26.6201.00 24.84C
ATOM10632CB LYSK37 -8.016-27.180 27.9651.0025.61C
ATOM10633CG LYSK37 -9.444-27.775 27.9441.0029.79C
ATOM10634CD LYSK37 -10.447 -27.004 27.0561.00 31.63C
ATOM10635CE LYSK37-11.894-27.264 27.5511.00 33.52C
ATOM10636NZ LYSK37-12.934 -26.654 26.6581.00 34.84N
ATOM10637C LYSK37 -6.058 -26.112 26.8011.0023.61C
[0483]ATOM10638O LYSK 37-5.144-26.81127.2421.0022.98OATOM10639N THRK 38-5.895 -24.84126.4911.0022.80N
ATOM10640CA THRK 38-4.591 -24.22126.5631.0022.11C
ATOM10641CB THRK 38-4.365 -23.23025.3971.0021.66C
ATOM10642OGl THRK 38-4.170 -23.99324.2211.00 20.51O
ATOM10643CG2THRK 38-3.041 -22.33925.6011.00 20.83C
ATOM10644C THRK 38-4.305 -23.63527.9431.0020.46C
ATOM10645O THRK 38-4.934-22.71828.4231.00 20.68O
ATOM10646N VALK 39-3.377-24.24128.6201.0021.84N
ATOM10647CA VALK 39-2.825 -23.61529.8651.00 19.91C
ATOM10648CB VALK 39-1.525 -24.27430.2651.0020.85C ATOM10649CGl VALK 39-0.901 -23.61331.6011.0015.97C
ATOM10650CG2VALK 39-1.808 -25.77430.4501.0016.57C
ATOM10651C VALK 39-2.680-22.11929.8221.0019.24C
ATOM10652O VALK 39-2.248 -21.55128.8271.0018.10O
ATOM10653N SERK 40-3.106-21.47130.9231.0021.15N
ATOM10654CA SERK 40-2.798 -20.05631.2101.0019.89C
ATOM10655CB SERK 40-4.042-19.22730.9721.00 20.77C
ATOM10656OG SERK 40-3.750-17.86030.8611.00 15.54O
ATOM10657C SERK 40-2.405 -19.95432.6661.0020.73C
ATOM10658O SERK 40-3.028 -20.59833.5001.0020.83O
ATOM10659N ASNK 41-1.372-19.15832.9951.0020.14N
ATOM10660CA ASNK 41-0.904-19.14134.3701.0019.39C
ATOM10661CB ASNK 41-0.065 -17.88634.6801.0017.80C
ATOM10662CG ASNK 411.214-17.88733.9831.0010.41C
ATOM10663ODl ASNK 411.537-16.95233.3171.0016.42O
ATOM10664ND2ASNK 411.932-18.94234.0661.00 9.11N
ATOM10665C ASNK 41-2.029-19.21435.3751.0020.64C
ATOM10666O ASNK 41-2.880-18.35135.3971.0019.75O
ATOM10667N GLYK 42-2.004 -20.24136.2251.0022.20N
ATOM10668CA GLYK 42-2.902 -20.28337.3551.00 23.21C
ATOM10669C GLYK 42-4.238 -20.89437.0231.0024.72C
ATOM10670O GLYK 42-5.103 -20.97537.8961.0024.74O
ATOM10671N LEUK 43-4.442-21.29835.7701.0025.07N
ATOM10672CA LEUK 43-5.634 -22.06835.4601.00 27.00C
ATOM10673CB LEUK 43-5.812-22.21033.9451.00 27.29C
ATOM10674CG LEUK 43-7.041 -21.52833.3411.0028.90C
ATOM10675CDl LEUK 43-7.321 -20.13233.9001.0027.77C
ATOM10676CD2LEUK 43-6.939 -21.53931.7931.0029.15C
ATOM10677C LEUK 43-5.586-23.44036.1121.0026.48C
ATOM10678O LEUK 43-4.586-24.16936.0421.0026.79O
ATOM10679N GLUK 44-6.679 -23.78736.7601.0026.54N
ATOM10680CA GLUK 44-6.863-25.11937.2981.00 26.77C
ATOM10681CB GLUK 44-7.921 -25.10438.4081.0026.39C
[0484]ATOM10770CD ARGK55-0.969 -31.608 20.341 1.00 23.31 C
ATOM10771NE ARGK55-1.393 -32.894 19.820 1.0024.59N
ATOM10772CZ ARGK55-2.350-33.649 20.359 1.00 27.87C
ATOM10773NHl ARGK55-2.996-33.240 21.467 1.0028.85N
ATOM10774NH2ARGK55-2.691 -34.799 19.767 1.00 24.45N
ATOM10775C ARGK551.965 -29.320 23.617 1.0018.61C
ATOM10776O ARGK551.217-28.481 24.087 1.00 18.69O
ATOM10777N VALK563.278 -29.139 23.424 1.0019.32N·
ATOM10778CA VALK563.946 -27.928 23.875 1.0019.00C
ATOM10779CB VALK564.998 -28.199 24.981 1.0019.69C
ATOM10780CGl VALK565.575 -26.894 25.461 1.0020.31C
ATOM10781CG2VALK564.401 -28.933 26.133 1.0018.25C
ATOM10782C VALK564.647 -27.242 22.719 1.0019.21C
ATOM10783O VALK565.712 -27.660 22.287 1.0017.35O
ATOM10784N GLUK574.048 -26.150 22.254 1.0020.55N
ATOM10785CA GLUK574.567 -25.444 21.106 1.00 21.98 C
ATOM10786CB GLUK573.451 -24.742 20.359 1.0021.90C
ATOM10787CG GLUK572.317-25.648 19.851 1.00 24.07 C
ATOM10788CD GLUK571.453 -24.884 18.844 1.00 32.18 C
ATOM10789OEl GLU K571.863-23.741 18.521 1.00 33.48O
ATOM10790OE2GLUK570.378 -25.386 18.384 1.00 33.07O
ATOM10791C GLUK575.671 -24.457 21.517 1.00 22.43C
ATOM10792O GLUK575.540-23.730 22.503 1.00 19.69O
ATOM10793N VALK586.769 -24.473 20.768 1.0023.54N
ATOM10794CA VALK587.816-23.494 21.049 1.00 26.08C
ATOM10795CB VALK589.128 -24.117 21.555 1.00 25.19C
ATOM10796CGl VALK588.857 -25.449 22.260 1.0026.34C
ATOM10797CG2VALK5810.128 -24.266 20.468 1.0028.01C
ATOM10798C YALK587.996 -22.535 19.874 1.0027.08C
ATOM10799O VALK587.770 -22.901 18.694 1.0027.07O
ATOM10800N GLYK598.337-21.296 20.224 1.0027.53N
ATOM10801CA GLYK598.438 -20.223 19.278 1.0028.04C
ATOM10802C GLYK599.838-20.251 18.752 1.0029.18C
ATOM10803O GLYK5910.405 -21.324 18.545 1.0029.26O
ATOM10804N GLYK6010.400-19.063 18.581 1.00 30.96N
ATOM10805CA GLYK6011.659-18.879 17.841 1.00 32.66C
ATOM10806C GLYK6011.310-18.688 16.372 1.00 33.11C
ATOM10807O GLYK6010.164-18.915 15.976 1.00 33.27O
ATOM10808N ASNK6112.274-18.258 15.569 1.00 33.35N
ATOM10809CA ASNK6112.079-18.233 14.123 1.0034.44 C
ATOM10810CB ASNK6111.876-16.814 13.538 1.00 35.25 C
ATOM10811CG ASNK6110.398-16.541 13.164 1.00 38.83 C
ATOM10812ODl ASN K619.827-17.173 12.246 1.0043.23O
ATOM10813ND2ASNK619.774-15.618 13.880 1.0040.33N
[0487]ATOM10814C ASNK 61 13.070-19.073 13.3411.00 33.79CATOM10815O ASNK 61 13.061 -19.074 12.1161.00 33.48O
ATOM10816N ASPK 62 13.914-19.821 14.0341.00 34.28N
ATOM10817CA ASPK 62 14.595 -20.875 13.3161.00 33.93C
ATOM10818CB ASPK 62 15.812-20.366 12.5561.00 35.48C
ATOM10819CG ASPK 62 16.991 -20.242 13.4191.00 35.25C
ATOM10820ODl ASP K 62 16.783 -19.727 14.5171.00 38.97O
ATOM10821OD2ASPK 62 18.073 -20.679 13.0211.00 33.38O
ATOM10822C ASPK 62 14.916-22.164 14.0311.00 33.76C
ATOM10823O ASPK 62 15.255-22.209 15.2421.00 33.71O
ATOM10824N METK 63 14.869 -23.200 13.1941.00 32.06N
ATOM10825CA METK 63 14.994-24.569 13.589 1.0031.21C
ATOM10826CB METK 63 14.501 -25.461 12.4641.00 30.31C
ATOM10827CG METK 63 13.043-25.269 12.1431.0031.63C
ATOM10828SD METK 63 12.579 -26.202 10.6711.00 32.63S
ATOM10829CE METK 63 14.104-26.144 9.7451.0034.10C
ATOM10830C METK 63 16.382 -24.994 14.0291.0029.48C
ATOM10831O METK 63 16.533 -26.071 14.5891.0029.17O
ATOM10832N ARGK 64 17.382 -24.167 13.7491.0028.60N
ATOM10833CA ARGK 64 18.746-24.380 14.2411.0027.62C
ATOM10834CB ARGK 64 19.759-23.585 13.4061.0028.22C
ATOM10835CG ARGK 64 19.750-23.868 11.9021.0026.40C
ATOM10836CD ARGK 64 20.657-22.909 11.1631.00 25.28C
ATOM10837NE ARGK 64 20.198 -21.534 11.2711.00 22.89N
ATOM10838CZ ARGK 64 20.576 -20.529 10.4661.00 24.42C
ATOM10839NHl ARG K 64 21.419-20.731 9.4691.0024.01N
ATOM10840NH2ARGK 64 20.111 -19.301 10.6511.0023.25N
ATOM10841C ARGK 64 18.944-24.002 15.7241.0027.86C
ATOM10842O ARGK 64 19.974-24.321 16.3101.0029.59O
ATOM10843N THRK 65 18.011 -23.270 16.3161.0027.23N
ATOM10844CA THRK 65 18.082-22.968 17.7471.0026.82C
ATOM10845CB THRK 65 17.451-21.608 18.0851.0027.01C
ATOM10846OGl THRK 65 17.553 -20.747 16.9511.0028.04O
ATOM10847CG2THRK 65 18.131 -20.950 19.3071.0028.41C
ATOM10848C THRK 65 17.326 -24.062 18.4851.0026.42C
ATOM10849O THRK 65 16.166 -24.426 18.1051.0026.48O
ATOM10850N PHEK 66 17.978 -24.588 19.5141.0024.90N
ATOM10851CA PHEK 66 17.452 -25.670 20.3291.0024.75C
ATOM10852CB PHEK 66 18.493 -26.786 20.5131.0025.62C
ATOM10853CG PHEK 66 18.633-27.733 19.3361.00 27.31C
ATOM10854CDl PHEK 66 17.765 -27.692 18.2551.0032.37C
ATOM10855CEl PHEK 66 17.890 -28.584 17.1691.0031.73C
ATOM10856CZ PHEK 66 18.848 -29.578 17.1961.0032.22C
ATOM10857CE2PHEK 66 19.708 -29.672 18.2991.00 34.92C
[0488]ATOM10902O METK718.937 -30.93735.7271.00 17.21O
ATOM10903N VALK727.902-29.15636.4131.0017.19N
ATOM10904CA VALK728.162-29.52737.7681.0017.63C
ATOM10905CB VALK729.445 -28.73838.3001.0018.29C
ATOM10906CGl VALK7210.631-29.15737.5411.00 14.80C
ATOM10907CG2VALK729.197-27.26538.1511.0016.09C
ATOM10908C VALK727.051-29.15338.6721.0017.48C
ATOM10909O VALK726.318-28.23338.3911.0017.87O
ATOM10910N ASPK736.972 -29.87439.7751.0018.23N
ATOM10911CA ASPK736.027 -29.59240.8181.0021.17C
ATOM10912CB ASPK735.355 -30.89941.2251.0020.45C
ATOM10913CG ASPK734.217-30.70442.1591.00 24.05C
ATOM10914ODl ASPK733.939-29.54542.6201.00 24.58O
ATOM10915OD2ASPK733.548 -31.73642.3891.00 29.62O
ATOM10916C ASPK736.764-29.01542.0551.00 21.82C
ATOM10917O ASPK737.419 -29.75242.7621.0022.99O
ATOM10918N PROK746.651 -27.70042.2991.00 22.83N
ATOM10919CA PROK747.355 -27.13843.4451.0023.43C
ATOM10920CB PROK747.416-25.63843.1081.00 23.32C
ATOM10921CG PROK746.176 -25.40442.2631.00 23.65C
ATOM10922CD PROK745.894 -26.68541.5341.00 22.17C
ATOM10923C PROK746.599 -27.42044.7731.00 24.62C
ATOM10924O PROK747.084-27.06945.8561.00 23.06O
ATOM10925N ASPK755.438-28.09144.6661.00 24.58N
ATOM10926CA ASPK754.529-28.26745.7961.00 25.03C
ATOM10927CB ASPK753.133 -27.74645.4141.00 25.15C
ATOM10928CG ASPK753.113-26.30045.1551.00 24.30C
ATOM10929ODl ASP K753.647-25.53546.0001.00 26.04O
ATOM10930OD2ASPK752.588 -25.90944.0911.00 20.49O
ATOM10931C ASPK754.436 -29.72246.2601.00 25.07C
ATOM10932O ASPK753.421 -30.15646.8131.0027.13O
ATOM10933N ALAK765.461 -30.49645.9771.00 24.67N
ATOM10934CA ALAK 765.436-31.909 46.2461.0025.24C
ATOM10935CB ALAK766.210-32.650 45.1601.0025.01C
ATOM10936C ALAK766.021 -32.17947.6371.00 26.03C
ATOM10937O ALAK766.992-31.50748.0371.00 26.08O
ATOM10938N PROK775.392 -33.09148.4121.00 26.38N
ATOM10939CA PROK774.125 -33.826 48.1091.0027.12C
ATOM10940CB PROK774.239 -35.08748.9691.00 27.51C
ATOM10941CG PROK775.121 -34.609 50.2121.0026.59C
ATOM10942CD PROK775.961 -33.44549.7321.00 26.47C
ATOM10943C PROK772.880-33.03448.4951.0027.63C
ATOM10944O PROK771.761 -33.43348.1771.0028.30O
ATOM10945N SERK783.066-31.92349.2091.0027.42N[0490]ATOM10946CASERK78 1.967 -31.02149.5291.0025.99 C
ATOM10947CBSERK781.457 -31.29550.9441.0025.58C
ATOM10948OGSERK780.564 -30.28851.3641.0020.25 O
ATOM10949CSERK782.524 -29.62149.4531.00 27.54C
ATOM10950OSERK783.702 -29.42349.8031.0027.68O
ATOM10951NPROK791.695 -28.63549.0011.00 28.74N
ATOM10952CAPROK79 2.057 -27.22449.1101.0028.91 C
ATOM10953CBPROK790.825 -26.52748.5681.0028.13 C
ATOM10954CGPROK79-0.286 -27.52248.8371.0030.03 C
ATOM10955CDPROK79 0.365 -28.77148.3741.0028.31 C
ATOM10956CPROK792.323 -26.75250.5601.0029.81C
ATOM10957OPROK793.034 -25.76350.7601.00 29.68O
ATOM10958NSERK801.745-27.44951.5461.00 30.74N
ATOM10959CASERK80 1.851 -27.07452.9681.0031.47 C
ATOM10960CBSERK800.676 -27.64153.7701.00 30.46C
ATOM10961OGSERK80-0.514 -26.93953.4781.00 28.62O
ATOM10962CSERK803.179-27.50553.6001.00 32.24C
ATOM10963OSERK803.575 -26.97154.6301.00 34.09O
ATOM10964NASPK813.823 -28.48152.9731.00 32.39N
ATOM10965CAASPK815.095 -29.01953.3621.00 33.17C
ATOM10966CBASPK814.893 -30.13154.3861.00 33.30C
ATOM10967CGASPK816.200 -30.64754.9441.00 35.63C
ATOM10968ODl ASPK817.138-29.83355.1561.00 37.84O
ATOM10969OD2ASPK816.303 -31.87355.1691.00 38.77O
ATOM10970CASPK815.785 -29.60452.1271.00 33.41C
ATOM10971OASPK815.821 -30.83751.9871.00 33.77O
ATOM10972NPROK826.302 -28.72851.2161.00 33.85N
ATOM10973CAPROK82 6.905 -29.10249.9181.00 33.94 C
ATOM10974CBPROK82 7.053 -27.75349.2061.0033.57 C
ATOM10975CGPROK82 7.099-26.75550.2651.00 33.56 C
ATOM10976CDPROK82 6.274-27.25651.3781.00 33.53 C
ATOM10977CPROK828.276 -29.78149.9531.00 33.77C
ATOM10978OPROK829.165 -29.37949.2071.00 34.56O
ATOM10979NASNK838.438 -30.82850.7441.00 33.41N
ATOM10980CAASNK83 9.775 -31.40550.979 1.0032.96 C
ATOM10981CBASNK83 9.784-32.23352.280 1.0033.06 C
ATOM10982CGASNK83 9.038-33.51952.139 1.0030.20 C
ATOM10983ODl ASNK839.638 -34.57151.9521.00 32.09O
ATOM10984ND2ASNK837.727 -33.44952.1921.00 24.36N
ATOM10985CASNK8310.462-32.18549.8271.00 32.90C
ATOM10986OASNK8311.660-32.49649.9311.00 32.09O
ATOM10987NLEUK849.718 -32.50548.7531.00 32.22N
ATOM10988CALEUK8410.314-33.10647.543 1.0031.45 C
ATOM10989CBLEUK84 9.483 -34.27446.9801.0031.78 C
[0491]ATOM10990CG LEUK849.042 -35.39847.9031.00 33.63CATOM10991CDl LEU K848.123 -36.36347.1721.00 34.35C
ATOM10992CD2LEUK8410.259-36.12448.4901.00 35.92C
ATOM10993C LEUK8410.509-32.07646.4381.00 30.58C
ATOM10994O LEUK8410.778 -32.46945.3141.00 30.75O
ATOM10995N ARGK8510.351 -30.78446.7591.00 29.32N
ATOM10996CA ARGK 8510.547 -29.67645.8221.0028.40C
ATOM10997CB ARGK8510.259-28.35146.5291.0028.50C
ATOM10998CG ARGK 8510.655 -27.10445.7251.0028.05C
ATOM10999CD ARGK 8510.464 -25.84346.5131.0027.68C
ATOM11000NE ARGK85 9.047-25.61946.7391.0028.83N
ATOM11001CZ ARGK858.545 -24.57247.3721.00 27.63C
ATOM11002NHl ARG K859.345 -23.64147.8851.0021.99N
ATOM11003NH2ARGK857.225 -24.46747.4981.0026.40N
ATOM11004C ARGK8511.980 -29.63345.2591.00 28.34C
ATOM11005O ARGK8512.936 -29.51246.0391.0027.89O
ATOM11006N GLUK8612.143 -29.68443.9361.0027.01N
ATOM11007CA GLUK8611.032 -29.71442.9811.0027.69C
ATOM11008CB GLUK8611.310-28.80341.7671.0027.74C
ATOM11009CG GLUK8611.472-27.34742.0351.0029.19C
ATOM11010CD GLUK8612.521 -26.71841.1111.00 33.05C
ATOM11011OEl GLUK8612.655 -27.19039.9771.00 33.32O
ATOM11012OE2GLUK8613.215-25.75441.5101.0031.56O
ATOM11013C GLUK8610.870-31.12642.4841.00 26.19C
ATOM.11014O GLUK8611.852 -31.82242.3071.00 27.12O
ATOM11015N TYRK879.640-31.57542.2651.00 26.52N
ATOM11016CA TYRK879.456 -32.87341.6561.00 24.12C
ATOM11017CB TYRK878.172-33.53242.1311.00 26.13C
ATOM11018CG TYRK878.227 -34.99141.8361.00 26.48C
ATOM11019CDl TYRK878.950-35.86242.6671.00 26.99C
ATOM11020CEl TYRK879.033 -37.20442.3671.0029.04C
ATOM11021CZ TYRK878.400 -37.67141.2161.00 25.58C
ATOM11022OH TYRK87 8.497 -38.96440.8831.0028.88O
ATOM11023CE2TYRK877.737 -36.83640.3781.0024.19C
ATOM11024CD2TYRK877.652-35.49840.6861.00 24.98C
ATOM11025C TYRK879.422-32.67540.1531.00 23.63C
ATOM11026O TYRK878.651-31.85739.6611.0022.44O
ATOM11027N LEUK8810.270-33.42439.4401.0023.08N
ATOM11028CA LEUK8810.451 -33.32437.9861.0022.91C
ATOM11029CB LEUK8811.923 -33.69637.6221.00 21.86C
ATOM11030CG LEUK8812.409 -33.58836.1761.0020.87C
ATOM11031CDl LEUK8812.465 -32.16735.6511.0019.59C
ATOM11032CD2LEUK8813.734 -34.23635.9461.0021.44C
ATOM11033C LEUK889.439-34.21837.2171.00 23.63C
[0492]ATOM11034O LEUK 889.555 -35.434 37.241 1.0024.39OATOM11035N HISK 898.451 -33.623 36.548 1.00 23.39N
ATOM11036CA HISK 897.497-34.435 35.790 1.0023.53C
ATOM11037CB fflSK 896.100 -33.812 35.807 1.0023.48C
ATOM11038CG HISK 895.417-34.004 37.120 1.0025.07C
ATOM11039NDl HIS K 894.634 -35.100 37.384 1.00 26.84N
ATOM11040CEl HIS K 894.227 -35.058 38.640 1.00 27.80C
ATOM11041NE2 fflS K 894.756 -33.998 39.213 1.0021.90N
ATOM11042CD2HISK 895.519-33.328 38.287 1.0027.11C
ATOM11043C HISK 897.938 -34.848 34.399 1.00 22.94C
ATOM11044O HISK 897.528 -35.890 33.892 1.0025.15O ATOM11045N TRPK 908.783 -34.045 33.785 1.0022.54N
ATOM11046CA TRPK 909.101 -34.193 32.382 1.00 22.28C
ATOM11047CB TRPK 907.926-33.640 31.595 1.0021.19C
ATOM11048CG TRPK 907.821 -34.006 30.124 1.0023.04C
ATOM11049CDl TRP K 908.396 -35.071 29.466 1.0020.62C
ATOM11050NEl TRPK 907.995 -35.070 28.137 1.0020.58N
ATOM11051CE2TRPK 907.166 -33.994 27.921 1.0023.64C
ATOM11052CD2TRPK 906.999 -33.331 29.157 1.0021.72C
ATOM11053CE3TRPK 906.166 -32.201 29.210 1.00 22.93C
ATOM11054CZ3TRPK 905.522 -31.771 28.018 1.00 21.27C
ATOM11055CH2TRPK 905.690 -32.455 26.825 1.0020.22C
ATOM11056CZ2TRPK 906.496 -33.569 26.738 1.00 22.94C
ATOM11057C TRPK 9010.335-33.416 32.027 1.0021.91C
ATOM11058O TRPK 9010.468 -32.295 32.427 1.0021.26O
ATOM11059N LEUK 9111.218-33.995 31.213 1.0022.97N
ATOM11060CA LEUK 9112.357-33.224 30.689 1.0022.96C
ATOM11061CB LEUK 9113.623 -33.454 31.540 1.00 21.91C
ATOM11062CG LEUK 9114.922 -32.694 31.207 1.0022.79C
ATOM11063CDl LEUK 9114.786 -31.200 31.442 1.0020.69C
ATOM11064CD2LEUK 9115.994-33.203 32.104 1.00 24.83C
ATOM11065C LEUK 9112.614-33.518 29.214 1.0022.64C
ATOM11066O LEUK 9112.789 -34.672 28.839 1.0023.52O
ATOM11067N VALK 9212.612-32.462 28.391 1.0022.70N
ATOM11068CA VALK 9212.861 -32.557 26.962 1.00 22.32C
ATOM11069CB VALK 9211.520 -32.444 26.126 1.00 22.47C
ATOM11070CGl VALK 9211.736-32.704 24.625 1.00 22.87C
ATOM11071CG2VALK 9210.476-33.452 26.630 1.00 21.77C
ATOM11072C VALK 9213.890-31.520 26.526 1.0022.24C
ATOM11073O VALK 9213.777-30.363 26.854 1.0021.98O
ATOM11074N THRK 9314.902-31.968 25.781 1.0023.45N
ATOM11075CA THRK 9315.993 -31.116 25.259 1.0023.63C
ATOM11076CB THRK 9317.348 -31.617 25.846 1.00 23.86C
ATOM11077OGl THRK 9317.543 -32.999 25.509 1.0022.71O
[0493]ATOM11078CG2THRK 93 17.336-31.527 27.3711.00 24.60CATOM11079C THRK 93 16.042-31.111 23.7101.0023.95C
ATOM11080O THRK 93 15.401 -31.933 23.0811.00 23.53O
ATOM11081N ASPK 94 16.788 -30.187 23.1011.0024.06N
ATOM11082CA ASPK 94 17.050-30.242 21.6411.00 23.89C
ATOM11083CB ASPK 94 17.813-31.510 21.1971.0024.52C
ATOM11084CG ASPK 94 19.187 -31.714 21.8661.00 27.47C
ATOM11085ODl ASP K 94 19.626-32.898 21.9181.0029.65O·ATOM11086OD2ASPK 94 19.838-30.747 22.2931.0029.97O
ATOM11087C ASPK 94 15.736-30.195 20.8381.0023.42C
ATOM11088O ASPK 94 15.550-30.923 19.8601.0022.90O
ATOM11089N ILEK 95 14.840 -29.323 21.2821.0023.03N
ATOM11090CA ILEK 95 13.631 -28.962 20.6021.0020.90C
ATOM11091CB ILEK 95 12.619-28.386 21.5681.0020.62C
ATOM11092CGl ILE K 95 12.535 -29.275 22.8501.0019.29C
ATOM11093CDl ILE K 95 11.535-28.782 23.9271.0019.54C
ATOM11094CG2ILEK 95 11.286 -28.104 20.8031.00 19.27C
ATOM11095C ILEK 95 13.984 -27.857 19.6321.0021.80C
ATOM11096O ILEK 95 14.406 -26.764 20.0501.0022.27O
ATOM11097N PROK 96 13.856 -28.132 18.3201.00 21.53N
ATOM11098CA PROK 96 14.119-27.038 17.3791.00 20.94C
ATOM11099CB PROK 96 14.146-27.755 16.0161.0020.45C
ATOM11100CG PROK 96 14.320 -29.255 16.3421.0018.57C
ATOM11101CD PROK 96 13.552 -29.403 17.6191.0021.27C
ATOM11102C PROK 96 13.081 -25.913 17.4291.0021.31C
ATOM11103O PROK 96 11.866 -26.175 17.6101.0023.23O
ATOM11104N GLYK 97 13.537-24.683 17.2061.0020.01N
ATOM11105CA GLYK 97 12.670-23.523 17.0541.0021.11C
ATOM11106C GLYK 97 11.543 -23.753 16.0431.0023.05C
ATOM11107O GLYK 97 11.730-24.483 15.0721.0022.53O
ATOM11108N THRK 98 10.401 -23.110 16.2511.0022.44N
ATOM11109CA THRK 98 9.236 -23.236 15.3681.00 23.57C
ATOM11110CB THRK 98 9.559 -22.983 13.8191.00 24.64C
ATOM11111OGl THRK 98 10.011 -24.191 13.1851.00 25.16O
ATOM11112CG2THRK 98 10.593 -21.874 13.6281.0026.48C
ATOM11113C THRK 98 8.503 -24.547 15.5371.0021.82C
ATOM11114O THRK 98 7.457-24.748 14.9711.0021.63O
ATOM11115N THRK 99 9.032-25.425 16.3701.0021.64N
ATOM11116CA THRK 99 8.446 -26.760 16.5331.0020.06C
ATOM11117CB THRK 99 9.437 -27.922 16.1361.0020.36C
ATOM11118OGl THRK 99 10.295 -28.284 17.2101.00 23.59O
ATOM11119CG2THRK 99 10.231 -27.625 14.9231.00 19.18C
ATOM11120C THRK 99 7.686-27.011 17.8601.0018.61C
ATOM11121O THRK 99 6.834 -26.214 18.2541.0019.95O
[0494]ATOM11122N ALAK1007.981 -28.113 18.524 1.0017.49NATOM11123CA ALAK1007.259 -28.532 19.709 1.0018.06C
ATOM11124CB ALAK1005.845 -29.161 19.323 1.0016.46C
ATOM11125C ALAK1008.075 -29.561 20.440 1.00 17.81C
ATOM11126O ALAK1009.059 -30.076 19.915 1.0018.42O
ATOM11127N ALAK1017.627 -29.888 21.647 1.0019.27N
ATOM11128CA ALAK1018.265 -30.908 22.494 1.0018.75C
ATOM11129CB ALAK1017.637 -30.892 23.931 1.0019.21C
ATOM11130C ALAK1018.269 -32.291 21.903 1.00 19.05C
ATOM11131O ALAK1019.249 -33.015 22.098 1.0018.30O
ATOM11132N SERK1027.200 -32.683 21.144 1.0018.74N
ATOM11133CA SERK1027.216-33.949 20.408 1.0017.36C
ATOM11134CB SERK1025.849 -34.194 19.643 1.0017.40C
ATOM11135OG SERK1025.651 -33.183 18.639 1.0012.91O
ATOM11136C SERK1028.398 -34.096 19.435 1.0018.83C
ATOM11137O SERK1028.843 -35.189 19.144 1.0019.63O
ATOM11138N PHE K1038.897-32.993 18.901 1.00 22.13N
ATOM11139CA PHEK10310.087-32.990 18.012 1.0023.41C
ATOM11140CB PHEK10310.114-31.692 17.193 1.0022.95C
ATOM11141CG PHEK1039.031-31.580 16.143 1.0022.40C
ATOM11142CDl PHE K1037.735-31.264 16.486 1.00 24.18C
ATOM11143CEl PHEK1036.719-31.133 15.488 1.00 22.59C
ATOM11144CZ PHEK1037.069-31.284 14.132 1.0022.52C
ATOM11145CE2PHEK1038.359 -31.577 13.787 1.00 20.56C
ATOM11146CD2PHEK1039.347 -31.701 14.792 1.00 22.72C
ATOM11147C PHE K10311.468 -33.115 18.715 1.0024.47C
ATOM11148O PHE K10312.507 -33.332 18.037 1.00 25.53O
ATOM11149N GLY K10411.488 -32.968 20.043 1.0025.04N
ATOM11150CA GLYK10412.737-32.880 20.799 1.0024.82C
ATOM11151C GLYK10413.263 -34.183 21.347 1.0026.02C
ATOM11152O GLYK10412.850 -35.268 20.948 1.00 24.56O
ATOM11153N GLNK10514.206-34.092 22.281 1.0028.00N
ATOM11154CA GLNK10514.796-35.315 22.858 1.00 29.99 C
ATOM11155CB GLN K10516.327 -35.251 22.766 1.0030.89C
ATOM11156CG GLNK10517.050 -36.581 22.876 1.00 34.87 C
ATOM11157CD GLN K10516.678 -37.572 21.762 1.00 38.39 C
ATOM11158OEl GLNK10516.821 -37.279 20.558 1.00 38.87O
ATOM11159NE2GLNK10516.197 -38.758 22.173 1.00 39.03N
ATOM11160C GLNK10514.337 -35.584 24.294 1.0029.70C
ATOM11161O GLNK10514.798 -34.940 25.226 1.0029.32O
ATOM11162N GLUK10613.431 -36.540 24.476 1.0029.85N
ATOM11163CA GLUK10612.959 -36.884 25.831 1.00 29.64 C
ATOM11164CB GLU K10611.917-38.001 25.797 1.0029.93C
ATOM11165CG GLUK10611.167-38.169 27.083 1.00 28.24C
[0495]ATOM11254CG METK117 -1.566-34.384 51.445 1.0029.40C
ATOM11255SD METK117 -0.064-34.917 52.297 1.0028.25S
ATOM11256CE METK117 0.935 -35.440 50.909 1.0027.82C
ATOM11257C METK117 -2.828 -31.028 49.807 1.0027.16C
ATOM11258O METK117 -1.958-30.244 50.233 1.0024.83O
ATOM11259N GLYK 118 -3.802-30.647 48.973 1.00 24.76N
ATOM11260CA GLYK118 -3.870 -29.258 48.507 1.0023.38C
ATOM11261C GLYK118 -3.454-29.046 47.074 1.0022.78C·
ATOM11262O GLYK118 -2.993 -29.963 46.412 1.0024.70O
ATOM11263N ILEK119 -3.624 -27.827 46.596 1.00 23.08N
ATOM11264CA ILEK119 -3.397-27.446 45.202 1.0022.45C
ATOM11265CB ILEK119 -4.036 -26.071 44.861 1.0022.44C
ATOM11266CGl ILEK119 -5.484 -25.974 45.342 1.0023.36C
ATOM11267CDl ILEK119 -5.927 -24.530 45.527 1.0024.55C
ATOM11268CG2ILEK119 -4.063 -25.808 43.348 1.0021.07C
ATOM11269C ILE K119 -1.916-27.348 44.999 1.0022.62C
ATOM11270O ILEK119 -1.207 -26.666 45.776 1.0024.33O
ATOM11271N HIS K120 -1.449 -28.088 43.999 1.00 21.80N
ATOM11272CA HIS K120 -0.093-28.018 43.482 1.0019.78C
ATOM11273CB HIS K120 0.410-29.404 43.063 1.0018.67C
ATOM11274CG HIS K120 0.449-30.407 44.174 1.0013.15C
ATOM11275NDl HISK120 1.274-31.502 44.150 1.0010.52N
ATOM11276CEl HIS K120 1.092 -32.215 45.240 1.00 9.83C
ATOM11277NE2 HIS K120 0.174-31.616 45.971 1.00 9.27N
ATOM11278CD2 HIS K120 -0.259 -30.500 45.316 1.0010.23C
ATOM11279C HIS K120 -0.091 -27.191 42.229 1.0020.86C
ATOM11280O HIS K120 -1.029-27.328 41.349 1.0019.56O
ATOM11281N ARGK121 0.985 -26.408 42.106 1.0019.60N
ATOM11282CA ARGK121 1.399 -25.804 40.837 1.00 21.47C
ATOM11283CB ARGK121 2.248 -24.545 41.064 1.0020.79C
ATOM11284CG ARGK121 1.522 -23.385 41.718 1.00 21.54C
ATOM11285CD ARGK121 2.610-22.412 42.327 1.0021.87C
ATOM11286NE ARGK121 3.367 -23.039 43.406 1.0022.73N
ATOM11287CZ ARGK121 4.406 -22.469 44.047 1.0023.16C
ATOM11288NHl ARG K121 4.869 -21.264 43.707 1.0018.28N
ATOM11289NH2ARGK121 5.022-23.135 45.004 1.0023.32N
ATOM11290C ARGK121 2.208 -26.756 39.945 1.0022.21C
ATOM11291O ARGK121 3.061 -27.503 40.414 1.0022.38O
ATOM11292N LEUK122 1.985 -26.692 38.634 1.00 22.64N
ATOM11293CA LEU K122 2.776 -27.523 37.728 1.0023.16C
ATOM11294CB LEUK122 1.892-28.591 37.051 1.0023.84C
ATOM11295CG LEUK122 1.520-29.904 37.801 1.0023.95C
ATOM11296CDl LEUK122 2.725 -30.690 38.266 1.00 20.31C
ATOM11297CD2LEUK122 0.457 -29.799 38.974 1.00 21.94C[0498]ATOM11298C LEUK1223.397-26.55936.7341.0023.25C
ATOM11299O LEU K1222.717-25.89136.0051.0023.16O
ATOM11300N VALK1234.723 -26.43736.7951.0025.04N
ATOM11301CA VALK123 5.439 -25.30436.2251.00 23.10C
ATOM11302CB VALK123 6.493 -24.65137.2541.00 24.05C
ATOM11303CGl VALK1237.246 -23.50136.5941.0023.15C
ATOM11304CG2 VALK1235.817-24.10238.5421.0022.80C
ATOM11305C YALK1236.152 -25.85434.9981.00 22.30C·ATOM11306O VALK1236.786-26.89235.0811.0022.52O
ATOM11307N PHEK1246.035-25.13333.8841.0021.45N
ATOM11308CA PHEK124 6.765 -25.38532.6461.0020.91C
ATOM11309CB PHEK124 5.787 -25.37131.4671.0019.96C
ATOM11310CG PHE K124 4.829 -26.53331.4691.0021.63C
ATOM11311CDl PHEK1243.654-26.48332.2161.00 22.10C
ATOM11312CEl PHEK1242.747 -27.59532.2091.0018.88C
ATOM11313CZ PHE K124 3.059-28.72331.4771.0018.70C
ATOM11314CE2PHEK1244.237 -28.78430.7371.00 20.69C
ATOM11315CD2PHEK1245.129-27.70930.7501.0019.26C
ATOM11316C PHEK1247.779 -24.25832.4291.0019.92C
ATOM11317O PHEK1247.436-23.12332.5281.0019.04O
ATOM11318N VALK1259.017-24.59532.1051.0020.18N
ATOM11319CA VALK12510.042-23.59131.9171.00 19.40C
ATOM11320CB VALK12511.090 -23.61633.0901.0020.05C
ATOM11321CGl VALK12511.864-22.29133.1421.0018.72C
ATOM11322CG2 VALK12510.408 -23.81334.4391.0018.81C
ATOM11323C VALK12510.737-23.87730.6061.0020.00C
ATOM11324O VALK12511.293 -24.94930.4191.0019.86O
ATOM11325N LEUK12610.722 -22.91429.6941.0019.64N
ATOM11326CA LEUK12611.509-23.06728.4951.00 20.97C
ATOM11327CB LEUK12610.751 -22.44827.3391.0020.45C
ATOM11328CG LEU K12611.218-22.93625.9581.0022.58C
ATOM11329CDl LEU K12611.235-24.47925.9031.0016.53C
ATOM11330CD2LEUK12610.320-22.31124.8311.0020.41C
ATOM11331C LEUK12612.898 -22.37228.6251.0021.84C
ATOM11332O LEU K12612.964-21.24629.0701.0021.17O
ATOM11333N PHEK12713.969-23.04728.2091.0023.76N
ATOM11334CA PHE K12715.290-22.43828.0861.0025.47C
ATOM11335CB PHEK12716.303-23.19028.9551.0026.76C
ATOM11336CG PHE K12716.000-23.13830.4341.0026.36C
ATOM11337CDl PHEK12716.601 -22.19531.2411.0027.73C
ATOM11338CE! PHE K12716.353 -22.15332.6151.0026.71C
ATOM11339CZ PHE K12715.482 -23.06233.1891.0027.60C
ATOM11340CE2PI1EK12714.867-24.04032.3821.0029.54C
ATOM11341CD2PHEK12715.156-24.08131.0161.0028.45C
[0499]
[0500]ATOM11386CA GLNK133 25.156 -30.909 24.1631.00 50.08 CATOM11387CB GLN K133 25.257 -29.84025.2561.00 50.23 C
ATOM11388CG GLNK133 23.898-29.448 25.8391.0051.63 C
ATOM11389CD GLNK133 23.813 -27.99326.2471.00 53.98 C
ATOM11390OEl GLNK133 22.742 -27.38726.1861.00 53.35O
ATOM11391NE2 GLNK133 24.941 -27.42026.6711.00 54.28N
ATOM11392C GLN K133 24.473 -32.13924.7061.00 50.01C ATOM11393O GLNK133 23.358 -32.46624.3001.0049.98O
ATOM11394N THRK134 25.149 -32.82125.6211.00 50.32N
ATOM11395CA THRK134 24.554 -33.94926.3081.00 50.21 C
ATOM11396CB THRK134 25.566 -35.11826.5121.00 50.39C
ATOM11397OGl THRK134 26.547 -35.09425.4671.00 52.14O
ATOM11398CG2THRK134 24.854 -36.47026.4871.0048.96C
ATOM11399C THRK134 23.990 -33.45427.6421.0049.94C
ATOM11400O THRK134 24.686 -32.81028.4421.0049.27O
ATOM11401N VALK135 22.704 -33.72427.8321.0049.67N
ATOM11402CA VALK135 22.065 -33.60529.1251.00 49.71C
ATOM11403CB VALK135 20.780 -32.75229.0341.00 49.85C
ATOM11404CGl VALK135 20.029 -32.76230.3481.0048.53C
ATOM11405CG2VALK135 21.115-31.31328.5781.0049.48C
ATOM11406C VALK135 21.768 -35.02129.6381.0049.94C
ATOM11407O VALK135 21.087 -35.80728.9661.00 50.09O
ATOM11408N TYRK136 22.310-35.35930.8061.00 49.65N
ATOM11409CA TYRK136 21.992-36.63531.4451.0049.71C
ATOM11410CB TYRK136 23.172-37.18132.2611.00 50.93C
ATOM11411CG TYRK136 24.513-37.03031.5721.00 53.02C
ATOM11412CDl TYRK136 25.370 -35.96431.9001.00 54.26C
ATOM11413CEl TYRK136 26.608 -35.80631.2531.00 54.78C
ATOM11414CZ TYRK136 26.996 -36.72330.2781.00 54.44C
ATOM11415OH TYRK136 28.215-36.56529.6511.00 54.29 O
ATOM11416CE2 TYRK136 26.161-37.78929.9311.00 54.67C
ATOM11417CD2 TYRK136 24.924 -37.93530.5801.00 54.09C
ATOM11418C TYRK136 20.730 -36.51732.3111.00 48.68C
ATOM11419O TYRK136 20.507 -35.51233.0051.0048.88O
ATOM11420N ALAK137 19.881 -37.53332.2191.00 47.40N
ATOM11421CA ALAK137 18.673 -37.59333.0151.0045.97C
ATOM11422CB ALAK137 17.964-38.85132.7031.0045.76C
ATOM11423C ALAK137 19.117-37.58934.4721.00 45.06C
ATOM11424O ALAK137 20.016 -38.34734.8181.0045.64〇
ATOM11425N PROK138 18.536-36.71735.3291.0043.98N
ATOM11426CA PRO K138 18.771 -36.90136.7701.0042.25C
ATOM11427CB PRO K138 17.710-36.00237.4041.0041.49C
ATOM11428CG PROK138 17.578 -34.89136.4481.0041.80C
ATOM11429CD PROK138 17.683 -35.53335.0771.0043.89C
[0501]ATOM11430 C PRO K138 18.609 -38.365 37.2301.00 41.87CATOM11431O PRO K138 17.881 -39.171 36.5951.00 40.79O
ATOM11432 N GLYK139 19.302 -38.710 38.3181.0041.25N
ATOM11433CA GLYK139 19.257 -40.077 38.8401.00 40.12 C
ATOM11434 C GLYK139 17.921 -40.414 39.4861.00 39.03C
ATOM11435O GLYK139 17.616-41.597 39.7081.00 38.20O
ATOM11436 N TRPK140 17.161 -39.353 39.7921.0037.93N
ATOM11437 CA TRPK140 15.881 -39.380 40.5081.00 37.30C ATOM11438CB TRPK140 16.089 -39.510 42.0291.00 38.78C
ATOM11439 CG TRPK140 17.092-38.516 42.6191.0040.11C
ATOM11440 CDl TRPK140 16.846-37.243 43.0461.0041.23C
ATOM11441NEl TRPK140 18.005 -36.665 43.5191.0042.07N
ATOM11442CE2 TRPK140 19.025 -37.575 43.4091.00 42.31C
ATOM11443CD2TRPK140 18.491 -38.747 42.8371.0041.82C
ATOM11444CE3TRPK 140 19.343 -39.851 42.6221.0042.60C
ATOM11445CZ3 TRPK140 20.687-39.738 42.9581.0041.36C
ATOM11446CH2TRPK140 21.192-38.556 43.5211.0042.08C
ATOM11447CZ2TRPK140 20.378 -37.462 43.7521.00 43.31C
ATOM11448C TRPK140 15.140-38.077 40.2371.0035.39C
ATOM11449O TRPK140 15.777-37.064 39.9071.0035.27O
ATOM11450N ARGK141 13.814-38.088 40.4221.00 32.37N
ATOM11451CA ARGK141 12.974-36.917 40.114 1.00 30.00 C
ATOM11452CB ARGK141 11.607-37.337 39.5561.0029.19 C
ATOM11453CG ARGK141 11.668 -38.237 38.3581.0027.48 C
ATOM11454CD ARGK141 10.287-38.785 38.060 1.0026.14 C
ATOM11455NE ARGK141 10.266 -39.494 36.794 1.00 25.53 N
ATOM11456CZ ARGK141 9.917 -38.948 35.6321.00 27.39 C
ATOM11457NHl ARG K141 9.923 -39.688 34.5311.00 24.68N
ATOM11458NH2ARGK141 9.572 -37.661 35.5711.00 24.85N
ATOM11459C ARGK141 12.723 -35.931 41.2571.00 29.48C
ATOM11460O ARGK141 12.299 -34.812 40.9911.00 28.79O
ATOM11461N GLN K142 12.917 -36.342 42.5121.0028.64N
ATOM11462CA GLNK142 12.571 -35.460 43.626 1.0028.91 C
ATOM11463CB GLNK142 12.010-36.219 44.8411.00 29.57 C
ATOM11464 CG GLNK142 12.991 -37.090 45.656 1.00 33.05 C
ATOM11465CD GLNK142 13.362-38.406 44.9681.00 35.57 C
ATOM11466 OEl GLNK142 13.170 -38.574 43.7581.00 38.79O
ATOM11467 NE2GLNK142 13.922 -39.327 45.7291.00 34.91N
ATOM11468C GLNK142 13.787 -34.635 44.0061.00 27.92C
ATOM11469 O CiLNK 142 14.889 -35.068 43.7741.00 26.91O
ATOM11470 N ASN K143 13.549 -33.445 44.5331.0027.35N
ATOM11471CA ASNK143 14.599-32.529 45.0131.00 30.22 C
ATOM11472 CB ASNK143 15.357 -33.096 46.2371.0029.64 C
ATOM11473CG ASNK143 14.416-33.379 47.4191.00 30.91 C
[0502]ATOM11474ODl ASN K143 13.833-32.46547.9931.0035.26OATOM11475ND2ASNK 143 14.256 -34.64147.7641.00 32.28N
ATOM11476C ASNK143 15.487 -32.03443.8781.00 30.44C
ATOM11477O ASNK143 16.684-31.67644.0491.0031.47O
ATOM11478N PHEK144 14.840-31.97942.7211.00 30.64N
ATOM11479CA PHE K144 15.324-31.27241.5471.0030.59 C
ATOM11480CB PHEK144 14.403 -31.59740.3501.00 30.94C
ATOM11481CG PHE K144 14.909 -31.09139.0351.00 30.64 C
ATOM11482CDl PHE K144 16.004-31.69438.4131.00 30.74C
ATOM11483CEl PHE K144 16.469-31.22537.1791.0028.24C
ATOM11484CZ PHEK144 15.833-30.13536.5671.00 29.55C
ATOM11485CE2PHEK144 14.776-29.51937.1931.0031.26C
ATOM11486CD2PHEK144 14.304-30.00638.4201.0031.82C
ATOM11487C PHEK144 15.411 -29.76541.7541.00 30.00C
ATOM11488O PHE K144 14.599-29.13642.4261.00 30.11O
ATOM11489N ASNK145 16.416-29.16441.1571.0031.19N
ATOM11490CA ASN K145 16.519-27.719 41.2191.0031.67 C
ATOM11491CB ASNK145 17.715-27.30842.0981.0031.30 C
ATOM11492CG ASN K145 17.731-25.819 42.3961.0031.32 C
ATOM11493ODl ASN K145 18.030-24.99541.5331.00 29.47O '
ATOM11494ND2ASNK145 17.383 -25.46743.6281.00 34.58N
ATOM11495C ASNK145 16.647 -27.20139.8011.0031.81C
ATOM11496O ASNK145 17.508 -27.64939.0691.00 33.39O
ATOM11497N THRK146 15.788 -26.27239.4041.00 32.55N
ATOM11498CA THRK146 15.770-25.820 38.0111.0032.38 C
ATOM11499CB THRK146 14.384-25.25337.5841.00 32.22 C
ATOM11500OGl THRK146 13.458 -26.33037.4151.00 33.63O
ATOM11501CG2THRK146 14.478 -24.51736.2541.0031.65C
ATOM11502C THRK146 16.912-24.83237.7511.00 32.70C
ATOM11503O THRK146 17.488 -24.84936.6591.00 32.12O
ATOM11504N LYS K147 17.232-24.00538.7601.00 32.30N
ATOM11505CA LYS K147 18.393 -23.10638.7291.00 33.02C
ATOM11506CB LYS K147 18.463 -22.23839.9901.00 33.25C
ATOM11507CG LYS K147 18.089 -20.80539.7791.00 35.06C
ATOM11508CD LYS K147 16.940 -20.36840.6981.00 38.52C
ATOM11509CE LYSK147 17.409_19.72342.0181.0039.26C
ATOM11510NZ LYS K147 16.217-19.19942.8671.00 37.47N
ATOM11511C LYS K147 19.691 -23.85938.5781.00 32.91C
ATOM11512O LYS K147 20.441 -23.62937.6351.0034.36O
ATOM11513N ASPK148 19.975 -24.73539.5311.00 32.35N
ATOM11514CA ASPK148 21.142 -25.60339.4781.0030,49C
ATOM11515CB ASPK148 21.015-26.68940.5521.00 29.88C
ATOM11516CG ASPK148 21.286 -26.17241.9781.00 32.17C
ATOM11517ODl ASPK148 21.634 -24.98042.1731.0028.65O
[0503]ATOM11518OD2ASPK14821.161 -26.996 42.910 1.00 34.12OATOM11519C ASPK14821.293 -26.256 38.113 1.0029.98C
ATOM11520O ASPK14822.396 -26.301 37.544 1.00 30.22O
ATOM11521N PHE K14920.186 -26.816 37.616 1.00 29.30N
ATOM11522CA PHE K14920.151 -27.496 36.332 1.00 29.01C
ATOM11523CB PHEK14918.764-28.120 36.113 1.00 28.91C
ATOM11524CG PHE K14918.619-28.829 34.793 1.00 29.23C ATOM11525CDl PHE K14918.931 -30.163 34.679 1.00 29.09C
ATOM11526CEl PHEK14918.791 -30.845 33.442 1.00 33.36C
ATOM11527CZ PHEK14918.338-30.160 32.314 1.0031.28C
ATOM11528CE2PHEK14918.019-28.808 32.420 1.0032.38C
ATOM11529CD2PHEK14918.169 -28.141 33.656 1.0031.53C
ATOM11530C PHE K14920.496-26.550 35.173 1.0029.23C
ATOM11531O PHEK14921.230-26.920 34.268 1.0029.90O
ATOM11532N ALAK15019.924-25.353 35.185 1.00 30.04N
ATOM11533CA ALAK150 20.157-24.360 34.159 1.0031.53C
ATOM11534CB ALAK15019.233 -23.175 34.362 1.00 30.43C
ATOM11535C ALAK15021.625 -23.914 34.166 1.00 33.68C
ATOM11536O ALAK15022.188-23.598 33.108 1.00 33.10O
ATOM11537N GLUK15122.243 -23.886 35.349 1.00 35.77N
ATOM11538CA GLUK15123.654 -23.489 35.473 1.00 38.32C
ATOM11539CB GLUK15123.916-22.891 36.865 1.00 39.00C
ATOM11540CG GLUK15125.103 -23.431 37.638 1.0044.38C
ATOM11541CD GLUK15126.385 -22.647 37.389 1.00 50.60C
ATOM11542OEl GLUK15127.454 -23.289 37.216 1.00 53.06O
ATOM11543OE2 GLUK15126.317-21.395 37.362 1.00 52.01O
ATOM11544C GLUK15124.608 -24.637 35.070 1.00 38.73C
ATOM11545O GLUK15125.564 -24.408 34.320 1.00 39.32O
ATOM11546N LEUK15224.309 -25.870 35.500 1.00 38.68N
ATOM11547CA LEU K15225.105 -27.043 35.128 1.00 38.47C
ATOM11548CB LEUK15224.497 -28.320 35.732 1.00 38.00C
ATOM11549CG LEU K15225.204-29.667 35.516 1.00 38.84C
ATOM11550CDl LEUK15226.589-29.731 36.220 1.00 39.05C
ATOM11551CD2LEUK15224.341 -30.828 35.987 1.00 38.39C
ATOM11552C LEUK15225.252-27.181 33.594 1.00 38.66C
ATOM11553O LEU K15226.328 -27.460 33.067 1.00 38.41O
ATOM11554N TYRK15324.138-27.032 32.900 1.00 38.18N
ATOM11555CA TYRK15324.124 -26.991 31.464 1.00 38.16C
ATOM11556CB TYRK15322.919 -27.788 30.949 1.00 37.29C
ATOM11557CG TYRK153 22.995 -29.210 31.417 1.00 35.53C
ATOM11558CDl TYRK15323.933 -30.071 30.867 1.00 35.13C
ATOM11559CEl TYRK15324.056-31.372 31.307 1.00 35.15C
ATOM11560CZ TYRK15323.241 -31.832 32.328 1.00 35.59C
ATOM11561OH TYRK153 23.392-33.146 32.727 1.00 35.83O[0504]ATOM11562CE2TYRK15322.287 -30.99032.8991.00 32.52C
ATOM11563CD2TYRK15322.178 -29.68232.4451.00 32.60C
ATOM11564C TYRK15323.992-25.51631.2101.00 38.92C
ATOM11565O TYRK15323.422 -24.79432.0301.0040.46O
ATOM11566N ASN K15424.497-25.01030.1141.00 38.95N
ATOM11567CA ASNK154 24.532-23.55930.055 1.00 38.50C ATOM11568CB ASN K154 25.855 -23.08429.484 1.0039.27C
ATOM11569CG ASNK154 26.994-23.42630.411 1.0039.63C
ATOM11570ODl ASN K15427.184 -22.76631.4311.00 42.50O
ATOM11571ND2ASNK15427.704 -24.50830.1121.0040.10N
ATOM11572C ASNK15423.296 -22.96329.4311.00 37.86C
ATOM11573O ASN K15423.312-22.44428.3141.00 38.18O
ATOM11574N LEUK15522.218-23.04130.2141.00 36.91N
ATOM11575CA LEUK15520.854-22.75129.763 1.00 35.00C
ATOM11576CB LEUK155 19.895 -23.71130.4521.00 34.60C
ATOM11577CG LEUK155 19.421 -24.94229.659 1.00 34.70C
ATOM11578CDl LEUK15519.243-26.13930.5971.00 30.74C
ATOM11579CD2LEUK15520.277 -25.30928.4081.00 32.10C
ATOM11580C LEUK15520.462-21.30730.0061.00 34.46C
ATOM11581O LEUK15519.486-20.81529.4231.00 34.03O
ATOM11582N GLYK15621.239-20.61230.8541.00 32.90N
ATOM11583CA GLYK15620.989-19.19331.129 1.00 30.51C
ATOM11584C GLYK15619.748-18.99731.9941.0029.28C
ATOM11585O GLYK15619.490-19.78132.8921.00 27.72O
ATOM11586N SERK15719.015-17.92131.7191.00 28.87N
ATOM11587CA SERK15717.700-17.65132.2701.0029.67C
ATOM11588CB SERK15717.530-16.14332.4201.00 30.21C
ATOM11589OG SERK157 18.579-15.63833.2441.00 34.45O
ATOM11590C SERK15716.577-18.22131.3721.0028.75C
ATOM11591O SERK15716.802-18.48830.1721.0028.40O
ATOM11592N PROK15815.376-18.44831.9491.00 28.20N
ATOM11593CA PRO K158 14.267-18.90231.058 1.0027.37C
ATOM11594CB PROK158 13.079-19.10632.0151.0026.85C
ATOM11595CG PROK158 13.652-19.10633.415 1.0027.08C
ATOM11596CD PROK158 14.984-18.39233.375 1.00 27.14C
ATOM11597C PRO K15813.911 -17.84729.9901.00 26.83C
ATOM11598O PROK15814.073 -16.63530.1941.0027.81O
ATOM11599N VALK15913.471 -18.32228.8421.0025.75N
ATOM11600CA VALK159 12.950-17.46227.8051.00 24.51C
ATOM11601CB VALK15913.563 -17.84426.4061.0024.73C
ATOM11602CGl VALK15915.078 -17.66126.4241.0023.76C
ATOM11603CG2VALK15913.269-19.29426.0501.0024.69C
ATOM11604C VALK15911.411-17.50027.8851.0023.73C
ATOM11605O VALK15910.730-16.67127.3071.00 23.67O
[0505]ATOM11650ODl ASN K165 -3.250 -22.175 40.413 1.0022.82O
ATOM11651ND2ASNK165 -1.751 -23.641 41.059 1.0013.07N
ATOM11652 C ASNK165 -3.761 -26.773 39.093 1.0022.82C
ATOM11653O ASN K165 -4.673 -26.891 38.242 1.0023.06O
ATOM11654N SERK166 -3.451 -27.730 39.971 1.0023.83N
ATOM11655CA SERK166 -4.167 -29.022 40.038 1.00 25.50C
ATOM11656CB SERK166 -3.526-30.053 39.091 1.0025.46C
ATOM11657OG SERK166 -4.331 -31.199 3 8.924 1.00 24.52O
ATOM11658C SERK166 -4.282 -29.598 41.476 1.00 26.30C
ATOM11659O SERK166 -3.388 -29.396 42.329 1.0026.27O
ATOM11660N GLN K167 -5.414-30.251 41.747 1.0026.01N
ATOM11661CA GLNK167 -5.676 -30.849 43.029 1.0027.30C
ATOM11662CB GLNK167 -6.421 -29.892 43.982 1.0025.98C
ATOM11663CG GLNK167 -7.637 -29.233 43.411 1.0027.18C
ATOM11664CD GLN K167 -8.406 -28.432 44.423 1.0027.23C
ATOM11665OEl GLNK167 -8.452 -28.770 45.611 1.00 30.35O
ATOM11666NE2GLNK167 -9.012-27.355 43.970 1.0025.91N
ATOM11667C GLN K167 -6.453 -32.149 42.852 1.00 28.81C
ATOM11668O GLN K167 -7.097 -32.351 41.840 1.0028.75O
ATOM11669N ARGK168 -6.369 -33.010 43.862 1.00 30.35N
ATOM11670CA ARGK168 -7.145 -34.237 43.975 1.0032.80C
ATOM11671CB ARGK168 -7.103 -34.676 45.438 1.0031.63C
ATOM11672CG ARG K168 -7.827 -35.943 45.792 1.00 32.70C
ATOM11673CD ARGK168 -7.763 -36.245 47.350 1.00 33.38C
ATOM11674NE ARGK168 -8.314-35.173 48.199 1.0031.77N
ATOM11675CZ ARG K168 -9.605 -35.034 48.477 1.00 30.35C
ATOM11676NHl ARGK 168-10.495 -35.866 47.942 1.00 34.91N
ATOM11677NH2 ARG K168 -10.026 -34.051 49.240 1.0025.24N
ATOM11678C ARGK168 -8.589-34.054 43.498 1.00 34.41C
ATOM11679O ARGK168 -9.235 -33.067 43.823 1.00 34.37O
ATOM11680N GLU K169 -9.076 -35.035 42.748 1.00 37.29N
ATOM11681CA GLUK 169-10.437-35.071 42.154 1.00 40.62C
ATOM11682CB GLUK 169-10.317-35.735 40.805 1.0040.33C
ATOM11683CG GLUK169-10.465 -34.864 39.611 1.00 43.63C
ATOM11684CD GLUK169-10.090-35.648 38.389 1.00 44.26C
ATOM11685OEl GLUK169-11.010-36.195 37.733 1.0044.50O
ATOM11686OE2GLUK169 -8.868 -35.763 38.145 1.0042.55O
ATOM11687C GLUK 169-11.366 -35.995 42.908 1.0042.15C
ATOM11688O GLUK169-12.008 -36.855 42.287 1.0042.91O
ATOM11689N ALAK170 -11.445 -35.829 44.225 1.0044.01N
ATOM11690CA ALAK170-11.818-36.913 45.143 1.0045.83C
ATOM11691CB ALAK170-13.090 -37.704 44.655 1.0046.22C
ATOM11692C ALAK170-10.594-37.853 45.322 1.0046.65C
ATOM11693O ALAK170-10.219-38.266 46.436 1.0046.67O
[0507]ATOM11694OXT ALA K170 -9.911 -38.201 44.340 1.00 47.33OTERATOM11695N ALAL3 -9.599 19.066 28.350 1.00 70.84N
ATOM11696CA ALAL3 -10.291 17.969 29.189 1.0070.93C
ATOM11697CB ALAL3 -9.978 18.434 30.813 1.00 71.08 C
ATOM11698C ALAL3-11.804 17.958 28.927 1.00 70.70C
ATOM11699O ALAL3 -12.446 19.009 29.054 1.00 70.78O
ΑΓΟΜ11700N GLYL4-12.397 16.803 28.577 1.00 70.51N·ATOM11701CA GLYL4-11.744 15.478 28.468 1.00 69.81C
ATOM11702C GLYL4-11.099 15.226 27.106 1.00 69.13C
ATOM11703O GLYL4-11.786 14.986 26.105 1.00 69.13O
ATOM11704N HISL5 -9.766 15.172 27.129 1.00 68.24N
ATOM11705CA HISL5 -8.897 15.614 26.058 1.00 67.38C
ATOM11706CB HIS L5 -9.443 16.924 25.487 1.00 67.36C
ATOM11707CG HISL5 -9.332 17.072 24.002 1.00 66.50C
ATOM11708NDl HIS L5 -8.799 18.196 23.412 1.00 64.80N
ATOM11709CEl HIS L5 -8.861 18.078 22.100 1.0064.06C
ATOM11710NE2HISL5 -9.443 16.929 21.813 1.00 65.62N
ATOM11711CD2HISL5 -9.757 16.284 22.987 1.00 66.91C
ATOM11712C HISL5 -7.682 15.983 26.898 1.00 66.96C
ATOM11713O HISL5 -7.792 16.766 27.843 1.00 66.90O
ATOM11714N ARGL6 -6.531 15.407 26.601 1.00 66.20N
ATOM11715CA ARGL6 -5.343 15.714 27.385 1.00 65.50 C
ATOM11716CB ARGL6 -4.172 14.763 27.031 1.0065.89 C
ATOM11717CG ARGL6 -3.797 14.618 25.531 1.00 67.63 C
ATOM11718CD ARGL6 -4.912 14.001 24.624 1.00 69.79 C
ATOM11719NE ARGL6 -5.556 12.823 25.210 1.0071.76 N
ATOM11720CZ ARGL6 -5.341 11.559 24.835 1.0072.77C
ATOM11721NHl ARG L6 -4.494 11.271 23.845 1.00 72.26N
ATOM11722NH2ARGL6 -5.989 10.573 25.455 1.0072.46N
ATOM11723C ARGL6 -4.945 17.195 27.294 1.00 64.36C
ATOM11724O ARGL6 -5.141 17.840 26.269 1.00 63.99O
ATOM11725N ASPL7 -4.430 17.732 28.398 1.00 63.18N
ATOM11726CA ASPL7 -3.715 19.016 28.388 1.0061.95C
ATOM11727CB ASPL7 -3.241 19.400 29.803 1.00 62.50C
ATOM11728CG ASPL7 -2.861 18.178 30.675 1.00 64.75C
ATOM11729ODl ASPL7 -3.509 18.004 31.739 1.00 66.84O
ATOM11730OD2ASPL7 -1.929 17.402 30.318 1.00 64.93O
ATOM11731C ASPL7 -2.528 18.969 27.411 1.00 60.21C
ATOM11732O ASPL7 -2.034 20.011 26.942 1.00 59.80O
ATOM11733N ARGL8 -2.106 17.738 27.108 1.00 58.11N
ATOM11734CA ARGL8 -0.992 17.441 26.190 1.00 55.71 C
ATOM11735CB ARGL8 -0.330 16.124 26.593 1.0055.67 C
ATOM11736CG ARGL8 0.910 16.292 27.468 1.00 57.06 C
[0508]ATOM11737CD ARGL 8 0.896 15.302 28.6331.00 58.57 CATOM11738NE ARGL 8 0.207 14.062 28.2771.00 59.15N
ATOM11739CZ ARGL 8 0.172 12.972 29.0391.00 59.64C
ATOM11740NHl ARG L 8 -0.48311.892 28.6131.00 60.18N
ATOM11741NH2ARGL 8 0.797 12.957 30.2111.0057.74N
ATOM11742C ARGL8 -1.38317.378 24.7061.00 53.66C
ATOM11743O ARGL8 -0.50917.240 23.8441.00 53.28O
ATOM11744N ASPL9 -2.68017.479 24.4131.00 50.92N
ATOM11745CA ASPL9 -3.16617.326 23.0401.0048.22C
ATOM11746CB ASPL9 -4.69217.296 22.9951.0047.94C
ATOM11747CG ASPL9 -5.21716.538 21.8011.0047.34C
ATOM11748ODl ASPL9 -5.82115.467 22.0081.0048.60O
ATOM11749OD2ASPL9 -5.01916.994 20.6591.0044.22O
ATOM11750C ASPL9 -2.63418.434 22.1431.00 46.17C
ATOM11751O ASPL9 -2.61719.586 22.5521.0045.77O
ATOM11752N PROL10 -2.15618.077 20.9331.0044.73N
ATOM11753CA PROL10 -1.751 19.078 19.9421.00 43.70C
ATOM11754CB PROL10 -1.540 18.251 18.6781.0043.87C
ATOM11755CG PROL10 -1.166 16.894 19.1741.0044.18C
ATOM11756CD PROL10 -1.921 16.702 20.4501.0044.71C
ATOM11757C PROL10 -2.81020.157 19.7101.0042.40C
ATOM11758O PROL10 -2.46021.320 19.4931.0042.15O
ATOM11759N LEUL11 -4.08219.767 19.7691.0041.15N
ATOM11760CA LEUL11 -5.20320.681 19.5381.0040.35C
ATOM 11761CB LEUL11 -6.50819.907 19.3261.00 39.59C
ATOM11762CG LEUL11 -6.753 19.208 17.9891.00 38.87C
ATOM11763CDl LEUL11 -8.13718.551 17.9691.00 35.95C
ATOM11764CD2LEUL11 -6.56220.176 16.8091.0037.35C
ATOM11765C LEUL11 -5.40121.678 20.6691.0040.50C
ATOM11766O LEUL11 -5.81022.799 20.4301.0040.39O
ATOM11767N VALL12 -5.13421.267 21.9081.0041.11N
ATOM11768CA VALL12 -5.19822.208 23.0231.0041.66C
ATOM11769CB VALL12 -5.69421.572 24.3971.0041.90C
ATOM11770CGl VALL12 -6.54420.292 24.1741.0041.35C
ATOM11771CG2VALL12 -4.54821.323 25.3501.0042.93C
ATOM11772C VALL12 -3.88723.017 23.1351.0041.67C
ATOM11773O VALL12 -3.93124.210 23.4191.0041.80O
ATOM11774N VALL13 -2.74022.381 22.8741.0042.11N
ATOM11775CA VALL13 -1.44523.087 22.8371.0041.88C
ATOM11776CB VALL13 -0.25422.101 22.6301.0042.54C
ATOM11777CGl VALL13 1.06922.858 22.3301.0042.71C
ATOM11778CG2VALL13 -0.07221.191 23.8571.0042.20C
ATOM11779C VALL13 -1.44924.152 21.7371.0041.92C
ATOM11780O VALL13 -0.85325.224 21.8821.0041.46O
[0509]ATOM11781N GLYL 14 -2.135 23.852 20.629 1.0041.72NATOM11782CA GLYL 14 -2.244 24.795 19.514 1.0040.48C
ATOM11783C GLYL 14 -3.369 25.782 19.702 1.0040.20C
ATOM11784O GLYL 14 -3.612 26.607 18.828 1.00 40.42O
ATOM11785N ARGL 15 -4.062 25.674 20.840 1.00 39.78N
ATOM11786CA ARGL 15 -5.126 26.593 21.281 1.00 39.40C
ATOM11787CB ARGL 15 -4.614 28.044 21.463 1.0040.31C
ATOM11788CG ARGL 15 -3.355 28.228 22.365 1.00 41.45C ATOM11789CD ARGL 15 -2.042 28.385 21.525 1.00 45.48C
ATOM11790NE ARGL 15 -0.869 29.090 22.130 1.0046.03N
ATOM11791CZ ARGL 15 -0.362 28.943 23.370 1.00 48.38C
ATOM11792NHl ARG L 15 -0.891 28.110 24.267 1.0048.43N
ATOM11793NH2ARGL 15 0.717 29.649 23.726 1.0047.60N
ATOM11794C ARGL 15 -6.388 26.533 20.406 1.00 39.07C
ATOM11795O ARGL 15 -7.252 27.403 20.487 1.0038.75O
ATOM11796N VALL 16 -6.488 25.502 19.564 1.00 38.75N
ATOM11797CA VALL 16 -7.715 25.250 18.781 1.00 38.00C
ATOM11798CB VALL 16 -7.477 24.185 17.660 1.0037.88C
ATOM11799CGl VALL 16 -8.762 23.870 16.938 1.00 38.07C
ATOM11800CG2VALL 16 -6.410 24.668 16.655 1.00 37.72C
ATOM11801C VALL 16 -8.869 24.848 19.719 1.00 37.67C
ATOM11802O VALL 16 -9.967 25.418 19.647 1.00 38.06O
ATOM11803N VALL 17 -8.637 23.846 20.571 1.00 37.00N
ATOM11804CA VALL 17 -9.471 23.679 21.752 1.0037.14C
ATOM11805CB VALL 17 -9.364 22.264 22.389 1.00 37.26C
ATOM11806CGl VALL 17-10.124 22.188 23.712 1.00 36.42C
ATOM11807CG2YALL 17 -9.917 21.197 21.411 1.00 37.07C
ATOM11808C VALL 17 -9.040 24.829 22.672 1.00 37.84C
ATOM11809O VALL 17 -7.851 24.952 23.026 1.00 36.77O
ATOM11810N GLYL 18-10.018 25.692 22.988 1.00 38.15N
ATOM11811CA GLYL 18 -9.755 27.040 23.471 1.0038.04C
ATOM11812C GLYL 18-10.376 28.153 22.626 1.00 37.86C
ATOM11813O GLYL 18-11.338 28.763 23.047 1.00 38.08O
ATOM11814N ASPL 19 -9.818 28.440 21.450 1.00 37.70N
ATOM11815CA ASPL 19-10.255 29.593 20.642 1.00 37.58C
ATOM11816CB ASPL 19 -9.115 30.109 19.769 1.00 37.69C
ATOM11817CG ASPL 19 -7.902 30.535 20.580 1.00 37.38C
ATOM11818ODl ASPL 19 -8.029 30.700 21.805 1.00 35.12O
ATOM11819OD2ASPL 19 -6.818 30.691 19.984 1.0040.08O
ATOM11820C ASPL 19-11.425 29.285 19.733 1.00 37.88C
ATOM11821O ASPL 19-12.134 30.197 19.256 1.00 37.91O
ATOM11822N VALL 20-11.627 27.999 19.479 1.00 37.45N
ATOM11823CA VALL 20-12.554 27.596 18.434 1.00 36.86C
ATOM11824CB VALL 20-11.770 27.088 17.185 1.00 36.69C
[0510]ATOM11825CGl VALL20-12.73226.59816.0881.00 36.17CATOM11826CG2VALL20-10.80728.18316.6661.00 34.79C
ATOM11827C VALL20-13.49526.54818.9771.00 36.47C
ATOM11828O YALL20-14.68426.62518.7741.00 36.87O
ATOM11829N LEUL21 -12.93525.58119.6981.0036.58N
ATOM11830CA LEUL 21-13.64124.34820.0491.00 36.05 C
ATOM11831CB LEUL21 -13.03923.15019.2911.00 35.61 C
ATOM11832CG LEUL 21-13.01423.16217.769 1.00 32.98 C
ATOM11833CDl LEUL21 -12.10022.04117.3191.0029.66C
ATOM11834CD2LEUL21 -14.43722.97417.2261.0031.27C
ATOM11835C LEUL21 -13.50424.05221.5161.00 36.45C
ATOM11836O LEUL21 -12.52324.46222.1601.00 35.03O
ATOM11837N ASPL22-14.48123.30322.0221.00 36.73N
ATOM11838CA ASPL22-14.34522.65123.3281.00 37.32C
ATOM11839CB ASPL22-15.71822.52923.9991.00 37.06C
ATOM11840CG ASPL22 -16.32023.87924.3271.00 38.79C
ATOM11841ODl ASP L22-15.54924.78424.7411.0039.55O
ATOM11842OD2ASPL22-17.54824.04324.1731.00 38.82O
ATOM11843C ASPL22 -13.69821.27923.1171.0037.50C
ATOM11844O ASPL22-13.63820.79521.9911.00 37.66O
ATOM11845N ALAL23 -13.20220.66524.1931.00 37.82N
ATOM11846CA ALAL 23 -12.63619.32724.1391.00 37.19 C
ATOM11847CB ALAL23 -12.09818.94925.4791.00 37.34 C
ATOM11848C ALAL23 -13.68418.31423.6861.00 37.52C
ATOM11849O ALAL23 -14.87318.46823.9601.00 37.75O
ATOM11850N PHEL24-13.23017.28322.9801.00 37.28N
ATOM11851CA PHEL24-14.11516.29322.3881.00 37.33C
ATOM11852CB PHEL24-14.61716.77621.0071.00 37.81C
ATOM11853CG PHEL24-13.52716.88719.9591.00 36.82 C
ATOM11854CDl PHEL24-12.69517.99119.9151.0037.13C
ATOM11855CEl PHEL24-11.71618.09518.9601.0039.15C·ATOM11856CZ PHEL24-11.54317.08718.0331.00 38.08C
ATOM11857CE2PHEL24-12.37715.97918.0641.0038.50C
ATOM11858CD2PHEL24-13.35815.89519.0121.00 37.89C
ATOM11859C PHEL24-13.34414.99022.2351.0037.22C
ATOM11860O PHEL24-12.11014.96922.3101.0036.80O
ATOM11861N VALL25 -14.06013.89322.0021.0037.20N
ATOM11862CA VALL25 -13.36512.64521.7031.00 36.28 C
ATOM11863CB VALL25 -13.84711.42722.6031.00 36.26C
ATOM11864CGl VALL25-15.01311.81023.5081.0036.14C
ATOM11865CG2VALL25-14.13410.15821.8011.00 35.45C
ATOM11866C VALL25 -13.32912.39920.1901.0036.15C
ATOM11867O VALL25 -14.37512.35719.5191.00 36.30O
ATOM11868N ARGL26-12.11312.25919.6661.00 35.67N
[0511]ATOM11869CA ARGL 26-11.89811.863 18.279 1.00 35.14 CATOM11870CB ARGL 26 -10.40611.767 17.965 1.00 34.95C
ATOM11871CG ARGL 26 -9.604 13.047 18.227 1.00 33.70 C
ATOM11872CD ARGL 26 -8.236 12.888 17.629 1.00 34.24 C
ATOM11873NE ARGL 26 -7.378 14.083 17.634 1.00 34.28 N
ATOM11874CZ ARGL26 -6.818 14.627 18.713 1.00 34.87 C
ATOM11875NHl ARG L26 -7.07514.138 19.920 1.00 36.05 N
ATOM11876NH2ARGL26 -6.03215.690 18.596 1.00 32.58N ATOM11877C ARGL26-12.55110.506 18.051 1.00 35.64C
ATOM11878O ARGL26-12.140 9.505 18.638 1.00 35.98O
ATOM11879N SERL27-13.56910.475 17.201 1.00 35.21N
ATOM11880CA SERL27 -14.278 9.234 16.912 1.0035.31C
ATOM11881CB SERL27-15.6559.262 17.552 1.0034.64C
ATOM11882OG SERL27-16.39310.374 17.098 1.00 32.44O
ATOM11883C SERL27-14.3788.880 15.421 1.00 36.15C
ATOM11884O SERL27-14.8747.817 15.082 1.00 37.14O
ATOM11885N THRL28-13.9029.754 14.540 1.00 37.25N
ATOM11886CA THRL28-13.957 9.502 13.096 1.00 38.52C
ATOM11887CB THRL28-15.12410.274 12.404 1.00 38.39C
ATOM11888OGlTHR L28-16.3939.774 12.874 1.00 39.50O
ATOM11889CG2THRL28-15.08010.109 10.897 1.00 39.54C
ATOM11890C THRL28-12.6129.887 12.507 1.00 39.08C
ATOM11891O THRL28-12.06910.944 12.849 1.00 39.56O
ATOM11892N ASNL29-12.0649.003 11.669 1.00 39.34N
ATOM11893CA ASNL29-10.843 9.280 10.902 1.00 39.54C
ATOM11894CB ASNL29-10.403 8.042 10.102 1.0040.06C
ATOM11895CG ASNL29-10.109 6.827 10.987 1.0042.04C
ATOM11896ODl ASN L29-10.6815.736 10.782 1.0042.88O
ATOM11897ND2ASNL29 -9.204 6.999 11.953 1.0040.37N
ATOM11898C ASNL29-11.02210.453 9.932 1.00 38.45C
ATOM11899O ASNL29-12.02210.524 9.199 1.00 38.63O
ATOM11900N LEUL30-10.03311.340 9.940 1.00 36.56N
ATOM11901CA LEUL30 -9.987 12.515 9.098 1.00 34.88 C
ATOM11902CB LEUL30 -10.22913.780 9.940 1.0035.01C
ATOM11903CG LEUL30-10.07915.126 9.205 1.0031.06C
ATOM11904CDl LEUL30-11.25015.324 8.213 1.0025.17C
ATOM11905CD2LEUL30-10.00516.240 10.184 1.00 26.61C
ATOM11906C LEUL30 -8.60712.653 8.483 1.0034.44C
ATOM11907O LEUL30 -7.61312.711 9.218 1.00 34.35O
ATOM11908N LYSL31 -8.54812.768 7.154 1.00 33.17N
ATOM11909CA LYSL31 -7.27813.009 6.466 1.0032.53C
ATOM11910CB LYSL31 -6.80711.740 5.738 1.00 32.84C
ATOM11911CG LYSL31 -5.31911.679 5.455 1.00 32.79C
ATOM11912CD LYSL31 -4.97210.620 4.414 1.0032.62C
[0512]ATOM11957CD LYSL373.92819.3590.552 1.00 39.58C
ATOM11958CE LYSL374.73019.8831.747 1.0044.53C
ATOM11959NZ LYSL376.10519.2841.821 1.0046.86N
ATOM11960C LYSL370.22216.5492.556 1.0037.56C
ATOM11961O LYSL37-0.55317.5032.580 1.00 37.08O
ATOM11962N THRL380.08715.4533.307 1.00 37.72N
ATOM11963CA THRL38-0.90115.2624.346 1.00 37.57 C
ATOM11964CB THRL38-0.86113.7934.785 1.00 38.34C
ATOM11965OGl THRL38-1.12412.9523.645 1.0040.18O
ATOM11966CG2THRL38-1.88613.4855.897 1.00 38.25C
ATOM11967C THRL38-0.64316.2065.542 1.00 37.82C
ATOM11968O THRL380.50316.3416.021 1.0037.87O
ATOM11969N VALL39-1.70716.8716.004 1.0036.61N
ATOM11970CA VALL39-1.62617.8187.101 1.00 35.17C
ATOM11971CB VALL39-2.81818.8167.050 1.00 35.44C
ATOM11972CGl VALL39-3.04319.5318.363 1.00 33.66C
ATOM11973CG2VALL39-2.64319.8135.901 1.00 34.65C
ATOM11974C VALL39-1.52117.1158.463 1.00 35.34C
ATOM11975O VALL39-2.31716.2188.789 1.00 34.29O
ATOM11976N SERL40-0.50617.5049.237 1.00 34.33N
ATOM11977CA SERL40-0.44217.11710.638 1.0034.38C
ATOM11978CB SERL400.79716.25810.964 1.00 34.26C
ATOM11979OG SERL402.03416.92510.680 1.00 35.02 O
ATOM11980C SERL40-0.51018.37411.481 1.00 34.10C
ATOM11981O SERL40-0.03919.44511.056 1.00 33.87O
ATOM11982N ASNL41-1.12818.26512.653 1.00 33.68N
ATOM11983CA ASNL41-1.30719.41513.534 1.00 33.75 C
ATOM11984CB ASNL41-1.68318.95214.947 1.00 34.24 C
ATOM11985CG ASNL41-3.16518.71215.101 1.00 33.67 C
ATOM11986ODl ASN L41-3.58817.72915.723 1.00 35.65O
ATOM11987ND2ASNL41-3.96519.61414.559 1.0031.21N
ATOM11988C ASNL41-0.06220.26713.611 1.00 33.24C
ATOM11989O ASNL410.98419.78013.969 1.00 32.70O
ATOM11990N GLYL42-0.16121.53213.250 1.0033.56N
ATOM11991CA GLYL420.98722.40713.404 1.00 33.54 C
ATOM11992C GLYL421.90922.40612.218 1.0034.46C
ATOM11993O GLYL422.83223.21712.178 1.0035.03O
ATOM11994N LEUL431.66721.51911.244 1.0034.10N
ATOM11995CA LEUL432.50121.46310.029 1.00 35.33 C
ATOM11996CB LEUL432.05220.3709.033 1.0034.72C
ATOM11997CG LEUL432.77920.2567.691 1.00 33.48C
ATOM11998CDl LEU L434.26219.8957.863 1.00 34.43C
ATOM11999CD2LEUL432.11119.2276.863 1.0031.57C
ATOM12000C LEUL432.39222.7899.341 1.00 36.27C
[0514]ATOM12001OLEUL 431.293 23.2649.120 1.00 37.70OATOM12002NGLUL 443.516 23.3928.986 1.00 36.97N
ATOM12003CAGLUL 44 3.454 24.6468.255 1.0037.35C
ATOM12004CBGLUL 444.670 25.4788.558 1.0037.72C
ATOM12005CGGLUL 444.378 26.9278.731 1.0041.54C
ATOM12006CDGLUL 445.653 27.6788.895 1.0045.78C ATOM12007OEl GLUL 445.994 28.03710.050 1.0047.21O
ATOM12008OE2GLUL 446.341 27.8417.868 1.0047.10O
ATOM12009CGLUL 443.361 24.4136.763 1.00 36.88C
ATOM12010OGLUL 444.025 23.5336.204 1.00 36.27O
ATOM12011NLEUL 452.537 25.2136.109 1.00 36.45N
ATOM12012CALEUL 452.465 25.1554.660 1.00 36.22C
ATOM12013CBLEUL 451.158 24.4444.197 1.00 35.33C
ATOM12014CGLEUL 450.960 22.9824.630 1.00 32.63C
ATOM12015CDl LEUL 45-0.497 22.4644.374 1.00 30.71C
ATOM12016CD2LEUL 451.963 22.0643.929 1.0031.28C
ATOM12017CLEUL 452.585 26.5614.086 1.00 36.63C
ATOM12018OLEUL 452.065 27.5114.668 1.0036.55O
ATOM12019NLYSL 463.287 26.6822.957 1.00 36.97N
ATOM12020CALYSL 463.350 27.9322.186 1.0036.98C
ATOM12021CBLYSL 464.398 27.8491.064 1.00 37.53C
ATOM12022CGLYSL 465.852 27.5561.502 1.00 39.96C
ATOM12023CDLYSL 466.286 28.4362.674 1.0043.18C
ATOM12024CELYSL 467.265 27.6893.572 1.0044.42C
ATOM12025NZLYSL 468.525 27.3702.846 1.00 42.48N
ATOM12026CLYSL 461.983 28.1661.565 1.00 36.41C
ATOM12027OLYSL 461.297 27.1931.230 1.00 36.85O
ATOM12028NPROL 471.562 29.4481.447 1.00 35.87N
ATOM12029CAPROL 470.311 29.8070.795 1.00 35.13C
ATOM12030CBPROL 470.357 31.3440.762 1.00 35.70C
ATOM12031CGPRO L 471.160 31.6921.981 1.00 35.32C
ATOM12032CDPROL 472.240 30.6361.999 1.00 35.57C
ATOM12033CPROL 470.183 29.217-0.601 1.00 34.70C
ATOM12034OPROL 47-0.931 28.848-1.000 1.00 34.83O
ATOM12035NSERL 481.291 29.069-1.316 1.0033.18N
ATOM12036CASERL 481.242 28.488-2.655 1.00 33.44C
ATOM12037CBSERL 482.562 28.653-3.387 1.00 33.76C
ATOM12038OGSERL 483.560 27.935-2.694 1.00 35.05O
ATOM12039CSERL 480.858 27.019-2.692 1.00 33.08C
ATOM12040OSERL 480.390 26.562-3.721 1.0033.07O
ATOM12041NMETL 491.056 26.293-1.583 1.00 32.81N
ATOM12042CAMETL 490.727 24.873-1.492 1.00 33.17C
ATOM12043CBMETL 491.493 24.227-0.331 1.00 33.53C
ATOM12044CGMETL 493.029 24.061-0.535 1.00 33.42C
[0515]ATOM 12045SD METL 49 3.979 24.073 1.032 1.00 37.94 SATOM12046CE METL 49 5.642 24.330 0.369 1.00 33.38 C
ATOM 12047C METL 49 -0.774 24.630 -1.284 1.00 32.10C
ATOM 12048O METL 49 -1.264 23.534 -1.536 1.00 30.80O
ATOM12049N VALL 50 -1.462 25.680 -0.813 1.0031.58N
ATOM 12050CA VALL 50 -2.828 25.629 -0.267 1.00 30.73 C
ATOM12051CB VALL 50 -2.833 25.832 1.308 1.0030.92 C
ATOM12052CGl VALL 50 -1.894 24.824 1.973 1.00 29.91C
ATOM12053CG2VALL 50 -2.474 27.278 1.758 1.00 30.53C
ATOM12054C VALL 50 -3.838 26.544 -1.011 1.0030.44C
ATOM12055O VALL 50 -4.923 26.840 -0.508 1.00 30.20O
ATOM12056N THRL 51 -3.479 26.951 -2.227 1.0029.64N
ATOM12057CA THRL 51 -4.335 27.794 -3.046 1.0029.68 C
ATOM12058CB THRL 51 -3.572 28.439 -4.246 1.00 30.20 C
ATOM12059OGl THRL 51 -3.642 27.596 -5.376 1.0031.12O
ATOM12060CG2THRL 51 -2.104 28.692 -3.930 1.00 29.87C
ATOM12061C THRL 51 -5.634 27.095 -3.526 1.0029.73C
ATOM12062O THRL 51 -6.659 27.770 -3.718 1.0029.53O
ATOM12063N HISL 52 -5.597 25.771 -3.702 1.0029.09N
ATOM12064CA HISL 52 -6.816 24.979 -4.020 1.00 29.00C
ATOM12065CB HISL 52 -6.655 24.177 -5.328 1.0028.88C
ATOM12066CG HISL 52 -6.406 25.037 -6.519 1.00 32.44C
ATOM12067NDl HIS L 52 -7.429 25.560 -7.286 1.00 34.77N
ATOM12068CElfflSL 52 -6.908 26.306 -8.248 1.00 37.13C
ATOM12069NE2HISL 52 -5.590 26.296 -8.121 1.00 35.88N
ATOM12070CD2HISL 52 -5.252 25.513 -7.046 1.00 33.39C
ATOM12071C HISL 52 -7.214 24.038 -2.893 1.00 28.00C
ATOM12072O HISL 52 -6.400 23.687 -2.050 1.0026.84O
ATOM12073N GLNL 53 -8.461 23.578 -2.909 1.0027.91N
ATOM12074CA GLNL 53 -9.001 22.911 -1.725 1.0027.79 C
ATOM12075CB GLNL 53 -10.498 22.631 -1.880 1.00 28.02C
ATOM12076CG GLNL 53 -10.863 21.769 -3.076 1.00 28.62C
ATOM12077CD GLNL 53-12.315 21.807 -3.327 1.0031.32C
ATOM12078OEl GLNL 53 -12.844 22.832 -3.756 1.0031.76O
ATOM12079NE2GLNL 53 -12.997 20.698 -3.051 1.0033.29N
ATOM12080C GLNL 53 -8.218 21.636 -1.531 1.00 28.00C
ATOM12081O GLNL 53 -7.815 21.016 -2.517 1.00 28.77O
ATOM12082N PROL 54 -7.984 21.230 -0.270 1.0027.46N
ATOM12083CA PROL 54 -7.312 19.941 -0.125 1.0027.16 C
ATOM12084CB PROL 54 -6.960 19.907 1.358 1.0026.41 C
ATOM12085CG PROL 54 -8.061 20.691 1.988 1.0025.86 C
ATOM 12086CD PROL 54 -8.322 21.829 1.029 1.0026.11 C
ATOM 12087C PROL 54 -8.259 18.769 -0.443 1.00 27.71C
ATOM 12088O PROL 54 -9.482 18.960 -0.528 1.00 26.94O
[0516]ATOM12133CB ASNL61 -20.6093.10010.029 1.0043.98C
ATOM12134CG ASNL61 -20.4282.81711.494 1.0046.73C
ATOM12135ODl ASN L61 -21.2823.18112.318 1.00 48.81O
ATOM12136ND2ASNL61-19.3182.16411.841 1.0049.01N
ATOM12137C ASNL61 -19.5853.1017.803 1.00 42.49C
ATOM12138O ASNL61 -19.0482.2167.142 1.0042.87O
ATOM12139N ASPL62 -20.4893.9327.307 1.00 41.79N ATOM12140CA ASPL62 -21.0573.7085.988 1.0040.91C
ATOM12141CB ASPL62 -22.1612.6396.056 1.00 41.54C
ATOM12142CG ASPL62 -23.3333.0426.947 1.0041.86C
ATOM12143ODl ASPL62 -24.1503.8766.513 1.0042.31O
ATOM12144OD2ASPL62-23.4732.4808.056 1.0042.19O
ATOM12145C ASPL62-21.5724.9755.351 1.00 39.68C
ATOM12146O ASPL62 -21.5516.0375.964 1.00 39.24O
ATOM12147N METL63 -22.0784.8264.130 1.00 38.37N
ATOM12148CA METL63 -22.4415.9353.269 1.00 37.22C
ATOM12149CB METL63 -22.4535.4841.803 1.00 36.73C
ATOM12150CG METL63 -21.1794.7571.429 1.00 36.91C
ATOM12151SD METL63 -20.8604.462-0.310 1.00 39.04S
ATOM12152CE METL63 -20.0332.898-0.185 1.00 37.06C
ATOM12153C METL63 -23.7486.5883.666 1.0036.18C
ATOM12154O METL63 -24.0957.6603.152 1.00 35.91O
ATOM12155N ARGL64 -24.4645.9704.604 1.00 35.55N
ATOM12156CA ARGL64 -25.7286.5535.071 1.0035.22C
ATOM12157CB ARGL64 -26.7475.4595.437 1.00 35.50C
ATOM12158CG ARGL64 -26.7394.2974.467 1.00 35.45C
ATOM12159CD ARGL64 -27.3753.0915.043 1.00 35.06C
ATOM12160NE ARGL64 -26.5462.4576.049 1.00 35.43N
ATOM12161CZ ARGL64 -26.8931.3386.677 1.00 38.76C
ATOM12162NHl ARG L64-28.0510.7556.378 1.0040.05N
ATOM12163NffiARGL64-26.1050.7997.599 1.00 37.34N
ATOM12164C ARGL64 -25.5157.5366.222 1.00 34.98C
ATOM12165O ARGL64 -26.4618.1716.670 1.00 35.05O
ATOM12166N THRL65 -24.2637.6806.669 1.00 34.88N
ATOM12167CA THRL65 -23.8888.6947.675 1.00 34.34C
ATOM12168CB THRL65 -22.9438.1048.747 1.00 34.60C
ATOM12169OGl THRL65 -23.5346.9069.274 1.00 34.72O
ATOM12170CG2THRL65 -22.7119.0989.896 1.0034.11C
ATOM12171C THRL65 -23.2529.9076.996 1.00 33.66C
ATOM12172O THRL65 -22.3079.7636.204 1.00 34.30O
ATOM12173N PHEL66-23.80311.0897.280 1.00 32.66N
ATOM12174CA PHEL66 -23.32112.3476.708 1.00 32.01C
ATOM12175CB PHEL66 -24.48013.1486.129 1.00 32.42C
ATOM12176CG PHEL66-25.19912.4254.996 1.00 33.89C
[0518]ATOM 12177CDl PHEL66-26.476 11.9135.1761.00 35.34CATOM 12178CEl PHEL66 -27.123 11.2174.1501.0037.11C
ATOM 12179CZ PHEL66-26.475 11.0392.9201.00 36.48C
ATOM 12180CE2PHEL66 -25.187 11.5272.7371.00 35.30C
ATOM 12181CD2PHEL66 -24.557 12.2073.7811.00 34.57C
ATOM12182C PHEL66 -22.469 13.1587.7091.0031.49C
ATOM12183O PHEL66 -22.704 13.1018.9151.00 30.74O
ATOM12184N TYRL67 -21.474 13.8657.1681.0029.91N
ATOM12185CA TYRL67 -20.504 14.6787.9131.0029.65C
ATOM12186CB TYRL67-19.112 14.0387.9341.00 29.84C
ATOM12187CG TYRL67-19.129 12.6418.5021.0031.53C
ATOM12188CDlTYR L67 -19.590 11.5447.7321.00 30.71C
ATOM12189CEl TYRL67 -19.648 10.2718.2721.0031.69C
ATOM12190CZ TYRL67-19.242 10.0599.5931.00 32.71C
ATOM12191OH TYRL67-19.291 8.80410.1521.00 32.56O
ATOM12192CE2TYRL67-18.790 11.12010.3711.00 32.87C
ATOM12193CD2TYRL67-18.752 12.4119.8191.0031.30C
ATOM12194C TYRL67 -20.402 16.0587.2821.0029.31C
ATOM12195O TYRL67 -20.673 16.2486.0811.00 29.01O
ATOM12196N THRL68 -20.005 17.0058.1231.0027.72N
ATOM12197CA THRL68 -19.926 18.3837.7871.0026.64C
ATOM12198CB THRL68 -21.019 19.2048.5641.00 27.01C
ATOM12199OGl THRL68 -22.280 19.0987.8661.00 25.41O
ATOM12200CG2THRL68 -20.657 20.6398.6641.00 24.56C
ATOM12201C THRL68-18.511 18.8158.1271.00 26.63C
ATOM12202O THRL68-18.006 18.5599.2231.00 25.86O
ATOM12203N LEUL69-17.875 19.4357.1361.0025.94N
ATOM12204CA LEUL69-16.521 19.9097.2531.0024.80C
ATOM12205CB LEUL69-15.655 19.3616.1071.00 24.10C
ATOM12206CG LEUL69-14.167 19.7436.1641.0020.89C
ATOM12207CDl LEUL69-13.399 18.8907.2511.0014.63C
ATOM12208CD2LEUL69-13.567 19.5684.7541.0016.54C
ATOM12209C LEUL69 -16.575 21.4177.1851.0025.35C
ATOM12210O LEUL69-17.343 21.9656.3991.00 24.46O
ATOM12211N VALL70-15.736 22.0358.0181.0025.43N
ATOM12212CA VALL70-15.642 23.4458.2921.00 25.95C
ATOM12213CB VALL70-16.269 23.7849.7151.00 26.69C
ATOM12214CGl VALL70-15.913 25.18810.2221.00 24.91C
ATOM12215CG2VALL70-17.792 23.5869.7151.0026.32C
ATOM12216C VALL70-14.147 23.7278.3171.0026.40C
ATOM12217O VALL70-13.379 22.9668.8741.0026.58O
ATOM12218N METL71 -13.744 24.8037.6591.00 27.00N
ATOM12219CA METL71 -12.370 25.2187.6351.00 27.44C
ATOM12220CB METL71 -11.741 24.8926.2971.00 26.96C
[0519]ATOM12221CG METL 71 -10.376 25.466 6.1021.0025.05CATOM12222SD METL 71 -9.859 25.415 4.3631.0027.46S
ATOM12223CE METL 71 -8.301 26.358 4.6211.0024.08C
ATOM12224C METL 71 -12.367 26.715 7.9111.0028.05C
ATOM12225O METL 71 -13.023 27.506 7.2061.0028.07O
ATOM12226N VALL 72-11.685 27.079 8.9861.0027.79N
ATOM12227CA VALL 72-11.701 28.449 9.4691.0028.13C
ATOM12228CB VALL 72 -12.647 28.663 10.7261.0027.95C
ATOM12229CGl VALL 72-14.110 28.500 10.3241.00 27.62C
ATOM12230CG2VALL 72-12.295 27.692 11.8711.0026.61C
ATOM12231C VALL 72 -10.285 28.893 9.7821.0028.98C
ATOM12232O VALL 72 -9.396 28.068 9.9561.0027.92O
ATOM12233N ASPL 73-10.121 30.208 9.7981.0030.30N
ATOM12234CA ASPL 73 -8.904 30.882 10.1661.0032.73C
ATOM12235CB ASPL 73 -8.421 31.766 9.0131.00 32.70C
ATOM12236CG ASPL 73 -7.190 32.569 9.3801.00 32.49C
ATOM12237ODl ASPL 73 -6.816 32.579 10.5631.0033.27O
ATOM12238OD2ASPL 73 -6.582 33.161 8.4731.00 30.94O
ATOM12239C ASPL 73 -9.228 31.730 11.4071.00 33.53C
ATOM12240O ASPL 73 -9.895 32.762 11.3081.00 34.60O
ATOM12241N PROL 74 -8.807 31.259 12.5841.00 34.00N
ATOM12242CA PROL 74 -9.073 32.005 13.8111.00 34.90C
ATOM12243CB PROL 74 -8.790 30.982 14.9281.0034.79C
ATOM12244CG PROL 74 -7.973 29.900 14.2951.00 34.14C
ATOM12245CD PROL 74 -8.072 29.999 12.8151.0033.54C
ATOM12246C PROL 74 -8.159 33.230 13.9681.00 35.87C
ATOM12247O PROL 74 -8.391 34.053 14.8461.0036.67O
ATOM12248N ASPL 75 -7.144 33.353 13.1181.0036.18N
ATOM12249CA ASPL 75 -6.164 34.419 13.2701.00 36.42C
ATOM12250CB ASPL 75 -4.742 33.817 13.3231.00 35.47C
ATOM12251CG ASPL 75 -4.576 32.824 14.4551.00 32.85C
ATOM12252ODl ASPL 75 -5.038 33.103 15.5741.00 34.34O
ATOM12253OD2ASPL 75 -4.004 31.744 14.2381.0029.97O
ATOM12254C ASPL 75 -6.257 35.482 12.1891.0036.95C
ATOM12255O ASPL 75 -5.250 35.990 11.7531.00 37.28O
ATOM12256N ALAL 76 -7.470 35.817 11.7731.0038.22N
ATOM12257CA ALAL 76 -7.713 36.813 10.720 1.00 38.63C
ATOM12258CB ALAL 76 -8.747 36.262 9.7151.00 39.07C
ATOM12259C ALAL 76 -8.216 3 8.139 11.3011.00 3 8.93C
ATOM12260O ALAL 76 -9.139 38.127 12.1141.0038.24O
ATOM12261N PROL 77 -7.637 39.295 10.8751.0039.51N
ATOM12262CA PROL 77 -6.530 39.587 9.9261.0040.27C
ATOM12263CB PROL 77 -6.472 41.128 9.8991.0040.34C
ATOM12264CG PROL 77 -7.724 41.594 10.4881.0039.41C
[0520]ATOM12265CD PROL77 -8.189 40.537 11.4381.00 39.20CATOM12266C PROL77 -5.163 39.10610.3861.0040.58C
ATOM12267O PROL77 -4.287 38.887 9.5641.0041.25O
ATOM12268N SERL78 -5.001 38.91611.6861.0041.63N
ATOM12269CA SERL78 -3.692 38.783 12.2981.0042.80C
ATOM12270CB SERL78 -3.147 40.19712.5711.00 42.32C
ATOM12271OG SERL78 -1.986 40.185 13.3621.0044.69O
ATOM12272C SERL78 -3.844 37.96813.5841.00 43.54C·
ATOM12273O SERL78 -4.852 38.10014.2841.00 43.21O
ATOM12274N PROL79 -2.851 37.11213.9071.00 44.57N
ATOM12275CA PROL79 -2.963 36.344 15.1531.0044.81C
ATOM12276CB PROL79 -1.779 35.383 15.0861.00 45.00C
ATOM12277CG PROL79 -0.782 36.063 14.1831.0044.79C
ATOM12278CD PROL79 -1.604 36.811 13.1781.0044.50C
ATOM12279C PROL79 -2.851 37.23816.3811.0045.20C
ATOM12280O PROL79 -3.353 36.88117.4571.0045.42O
ATOM12281N SERL80 -2.215 38.39616.2241.0045.07N
ATOM12282CA SERL80 -2.100 39.33817.3351.00 45.22C
ATOM12283CB SERL80 -0.859 40.22517.1751.0044.99C
ATOM12284OG SERL80 -1.182 41.408 16.4621.0045.37O
ATOM12285C SERL80 -3.397 40.16717.5031.0045.07C
ATOM12286O SERL80 -3.842 40.40218.6211.00 45.33O
ATOM12287N ASPL81 -4.002 40.57316.3851.0044.58N
ATOM12288CA ASPL81 -5.278 41.29316.3741.00 43.68C
ATOM12289CB ASPL81 -5.061 42.67515.7501.00 43.78C
ATOM12290CG ASPL81 -6.307 43.54815.7921.0044.00C
ATOM12291ODl ASP L81 -7.114 43.42016.7391.0045.75O
ATOM12292OD2ASPL81 -6.477 44.37214.8671.0042.51O
ATOM12293C ASPL81 -6.349 40.50515.5911.0043.16C
ATOM12294O ASPL81 -6.768 40.91714.4831.0043.53O
ATOM12295N PROL82 -6.824 39.37316.1551.00 42.45N
ATOM12296CA PROL82 -7.716 38.492 15.3681.0041.53C
ATOM12297CB PROL82 -7.610 37.156 16.0931.0041.14C
ATOM12298CG PROL82 -7.395 37.543 17.5321.0042.33C
ATOM12299CD PROL82 -6.573 38.832 17.5081.0042.08C
ATOM12300C PROL82 -9.181 38.93615.3011.0041.40C
ATOM12301O PROL82 -10.091 38.13515.5791.0040.67O
ATOM12302N ASNL83 -9.408 40.17214.8671.00 40.93N
ATOM12303CA ASNL83 -10.743 40.78414.9541.0040.54C
ATOM12304CB ASNL83 -10.633 42.31114.8451.0040.14C
ATOM12305CG ASNL83-10.011 42.76213.5461.00 40.04C
ATOM12306ODl ASNL83 -10.634 42.67212.4901.0035.55O
ATOM12307ND2ASNL83 -8.765 43.27213.6191.00 35.83N
ATOM12308C ASNL83-11.840 40.24014.0101.0040.54C
[0521]ATOM12353CG LEUL 88 -16.723 29.405 6.684 1.0021.03C
ATOM12354 CDl LEU L88-16.384 28.3647.7971.0012.91C
ATOM12355CD2LEUL88-18.228 29.4756.3971.00 19.51C
ATOM12356C LEUL88 -14.008 30.7075.6971.00 22.98C
ATOM12357O LEUL88 -14.268 31.5094.7691.0024.24O
ATOM12358N HISL89-13.153 29.6945.5581.0022.80N
ATOM12359CA HISL89-12.507 29.4714.2951.00 23.22C
ATOM12360CB HISL89-11.058 29.0744.4841.00 22.89C
ATOM12361CG HISL89-10.147 30.2454.6921.0024.24C
ATOM12362NDl HIS L89 -9.574 30.9333.6501.00 26.21N
ATOM12363CElfflSL89 -8.830 31.9184.1211.0028.53C
ATOM12364NE2fflSL89 -8.921 31.9075.4351.00 30.61N
ATOM12365CD2HISL89 -9.749 30.8735.8161.00 26.85C
ATOM12366C HISL89-13.274 28.5043.4061.0023.20C
ATOM12367O HISL89-13.172 28.5872.1791.0022.76O
ATOM12368N TRPL90-14.068 27.6304.0311.0023.39N
ATOM12369CA TRPL90-14.701 26.5323.3191.00 23.60C
ATOM12370CB TRPL90-13.598 25.5402.8891.0024.49C
ATOM12371CG TRPL 90-13.935 24.478 1.8531.00 25.51C
ATOM12372CDl TRPL90-14.865 24.5570.8541.00 24.30C
ATOM12373NEl TRPL90 -14.845 23.4140.1061.0025.66N
ATOM12374CE2TRPL90-13.895 22.5600.5951.0024.87C
ATOM12375CD2TRPL90-13.293 23.1981.7031.0026.64C
ATOM12376CE3TRPL90 -12.250 22.5362.3881.0027.25C
ATOM12377CZ3TRPL90-11.858 21.2531.9381.0024.55C
ATOM12378CH2TRPL90 -12.503 20.6410.8581.00 25.47C
ATOM12379CZ2TRPL90-13.524 21.2750.1711.0023.54C
ATOM12380C TRPL90-15.664 25.8664.2711.0023.36C
ATOM12381O TRPL90-15.401 25.7815.4731.0022.99O
ATOM12382N LEUL91 -16.777 25.3753.7241.0022.20N
ATOM12383CA LEUL 91 -17.736 24.600 4.482 1.0021.87C
ATOM12384CB LEUL 91-18.751 25.540 5.181 1.0021.91C
ATOM12385CG LEUL 91 -20.043 25.055 5.876 1.0022.41C
ATOM12386CDl LEU L91 -19.825 23.9486.8251.0024.32C
ATOM12387CD2LEUL91 -20.776 26.1746.5961.0023.05C
ATOM12388C LEUL91 -18.445 23.6863.4781.00 22.71C
ATOM12389O LEUL91 -18.869 24.1322.4121.0020.14O
ATOM12390N VALL92-18.486 22.4023.8351.0023.62N
ATOM12391CA VALL 92-19.021 21.333 3.035 1.00 24.73C
ATOM12392CB VALL 92-17.912 20.430 2.4031.00 24.22C
ATOM12393CGl VALL92 -18.507 19.5181.3281.0023.65C
ATOM12394CG2VALL92-16.761 21.2541.8421.00 23.70C
ATOM12395C VALL92-19.849 20.4893.9991.0025.80C
ATOM12396O VALL92 -19.473 20.3095.1731.0024.51O
[0523]ATOM12485N GLUL106 -21.230 21.574-1.3211.00 32.06N
ATOM12486CA GLU L106-20.429 22.774 -0.9171.00 32.68 C
ATOM12487CB GLUL 106-19.266 23.107-1.8751.00 33.73 C
ATOM12488CG GLUL 106-19.564 24.083-3.0171.00 35.01 C
ATOM12489CD GLUL 106-18.336 24.870 -3.4721.00 35.23 C
ATOM12490OEl GLUL106-17.205 24.332-3.4501.00 37.81O
ATOM12491OE2 GLUL106-18.511 26.045-3.8721.00 39.74O
ATOM12492C GLUL106 -21.236 24.011-0.5471.0031.61C
ATOM12493O GLUL106-22.003 24.564-1.3381.0031.62O
ATOM12494N VALL 107-21.068 24.4170.7031.00 30.62N
ATOM12495CA VAL L107 -21.846 25.5091.2941.0028.36C
ATOM12496CB VALL107-22.258 25.1212.7401.0029.77C
ATOM12497CGl VALL 107-22.669 26.3203.5651.0029.70C
ATOM12498CG2 VALL 107-23.391 24.1012.6991.00 27.74C
ATOM12499C VAL L107 -21.194 26.9051.1601.0027.15C
ATOM12500O VALL 107-21.796 27.8370.6181.00 24.66O
ATOM12501N METL108-19.979 27.0381.6871.0026.60N
ATOM12502CA METL108-19.106 28.1461.4211.00 24.89 C
ATOM12503CB METL108-18.480 28.6342.7431.0024.65 C
ATOM12504CG METL108-17.670 29.9252.590 1.00 23.29 C
ATOM12505SD METL108-18.582 31.3761.9711.0026.33S
ATOM12506CE METL108-19.436 31.8363.5081.0022.33C
ATOM12507C METL108-18.008 27.6400.4681.00 24.94C
ATOM12508O METL108-17.306 26.6870.7781.0025.34O
ATOM12509N SERL 109-17.850 28.248-0.6961.0026.16N
ATOM12510CA SERL109-16.813 27.808-1.6191.0027.34C
ATOM12511CB SERL 109-16.916 28.524-2.9691.0027.98C
ATOM12512OG SERL109-16.575 29.903-2.8761.00 30.64O
ATOM12513C SERL109-15.444 28.078-1.0051.00 28.20C
ATOM12514O SERL 109-15.300 28.985-0.1711.0028.52O
ATOM12515N TYRL110-14.459 27.284-1.4271.0027.57N
ATOM12516CA TYRL HO-13.088 27.388-0.9521.0026.32C
ATOM12517CB TYRL110-12.285 26.157-1.3991.00 25.61C
ATOM12518CG TYRL110-10.884 26.088-0.8281.0024.66C
ATOM12519CDl TYRL110 -9.798 26.666-1.5001.0024.53C
ATOM12520CEl TYRL HO -8.535 26.592-0.9711.0025.81C
ATOM12521CZ TYRL110 -8.351 25.9410.2461.0023.65 C
ATOM12522OH TYRL110 -7.127 25.826 0.786 1.0023.28 O
ATOM12523CE2 TYRL110 -9.402 25.3620.9101.00 23.86C
ATOM12524CD2 TYRL110-10.646 25.4320.3751.00 22.40C
ATOM12525C TYRL110-12.341 28.643-1.4011.0026.57C
ATOM12526O TYRL 110-12.201 28.934-2.6151.0025.08O
ATOM12527N GLUL 111-11.788 29.337-0.4041.00 26.48N
ATOM12528CA GLUL 111-10.912 30.480-0.6551.0026.31C
[0526]ATOM12529CB GLUL 111-11.515 31.742-0.0391.0027.53CATOM 12530CG GLUL 111 -10.776 33.038-0.3391.00 23.22C
ATOM 12531CD GLUL 111-11.472 34.2010.2711.00 24.19C
ATOM 12532OEl GLUL 111-12.259 34.843-0.4221.0025.44O
ATOM12533OE2 GLUL 111-11.216 34.5101.4501.0029.20O
ATOM12534C GLUL 111 -9.498 30.279-0.1201.0026.90C
ATOM12535O GLUL 111 -9.307 29.9101.0201.0026.97O
ATOM12536N SERL112 -8.523 30.546-0.9741.0026.50N
ATOM12537CA SERL112 -7.120 30.310-0.7191.00 26.61C
ATOM12538CB SERL112 -6.302 30.768-1.9441.00 26.84C
ATOM12539OG SERL112 -6.775 30.224-3.1861.0028.83O
ATOM12540C SERL112 -6.666 31.0890.5321.0026.09C
ATOM12541O SERL112 -6.855 32.2980.6101.0025.55O
ATOM12542N PROL113 -6.128 30.3951.5351.0026.13N
ATOM12543CA PROL113 -5.476 31.1802.6181.0027.19C
ATOM12544CB PROL113 -4.758 30.0973.4241.0026.18C
ATOM12545CG PROL113 -5.716 28.9013.3141.0025.81C
ATOM12546CD PROL113 -6.134 28.9451.8291.00 25.65C
ATOM12547C PRO L113 -4.491 32.2462.0841.0028.29C
ATOM12548O PRO L113 -3.617 31.9201.3041.0028.85O
ATOM12549N ARGL114 -4.678 33.5152.4241.00 30.46N
ATOM12550CA ARGL114 -3.646 34.5272.1091.00 33.53C
ATOM12551CB ARGL114 -4.111 35.5561.0601.00 33.20C
ATOM12552CG ARG L114 -4.606 34.938-0.3061.00 34.96C
ATOM12553CD ARGL114 -3.469 34.510-1.2431.00 37.32C
ATOM12554NE ARGL114 -2.597 35.647-1.5521.0041.00N
ATOM12555CZ ARGL114 -2.832 36.525-2.5311.0042.55C
ATOM12556NHl ARG L114 -3.894 36.394-3.3401.0041.44N
ATOM12557NH2ARGL114 -1.998 37.538-2.7121.0043.04N
ATOM12558C ARGL114 -3.156 35.1673.4261.00 34.78C
ATOM12559O ARGL114 -3.409 36.3353.7121.00 35.14O
ATOM12560N PROL115 -2.486 34.3694.2671.00 36.24N
ATOM12561CA PROL115 -2.086 34.9385.5511.00 37.71C
ATOM12562CB PROL115 -1.363 33.7856.2421.00 37.24C
ATOM12563CG PROL115 -0.988 32.8495.1501.00 36.64C
ATOM12564CD PROL115 -2.047 32.9734.1161.00 36.19C
ATOM12565C PRO L115 -1.123 36.0605.2681.0038.92C
ATOM12566O PROL115 -0.224 35.8794.4561.00 39.58O
ATOM12567N THRL116 -1.344 37.2395.8231.00 40.88N
ATOM12568CA THRL116 -0.257 38.1995.7681.00 43.33C
ATOM12569CB THRL116 -0.683 39.6945.7341.00 43.52C
ATOM12570OGl THRL116 -1.220 40.0174.4511.0043.71O
ATOM12571CG2 THRL116 0.551 40.5985.9361.0045.83C
ATOM12572C THRL116 0.580 37.8356.9901.00 44.27C
[0527]ATOM 12573O THRL116 1.339 36.818 6.983 1.0043.91OATOM 12574N METL117 0.409 38.609 8.059 1.0045.15N
ATOM 12575CA METL117 1.400 38.532 9.123 1.0046.42C
ATOM 12576CB METL117 2.606 39.391 8.764 1.0046.80C
ATOM 12577CG METL117 3.446 38.879 7.610 1.0046.07C
ATOM12578SD METL117 4.416 40.297 7.146 1.0049.61S
ATOM12579CE METL117 3.152 41.543 6.783 1.00 50.18C
ATOM12580C METL117 0.859 38.901 10.485 1.0045.43C
ATOM12581O METL117 0.276 39.979 10.641 1.0045.89O
ATOM12582N GLYL118 1.082 38.024 11.471 1.0044.75N
ATOM12583CA GLYL118 1.980 36.839 11.351 1.0042.57C
ATOM12584C GLYL118 1.436 35.472 10.933 1.0041.26C
ATOM12585O GLYL118 0.817 35.341 9.892 1.0041.86O
ATOM12586N ILEL119 1.695 34.446 11.741 1.0040.18N
ATOM12587CA ILE L119 1.374 33.029 11.415 1.00 39.10C
ATOM12588CB ILEL119 2.301 32.036 12.199 1.00 38.16C
ATOM12589CGl ILEL119 3.764 32.472 12.161 1.00 38.54C
ATOM12590CDl ILEL119 4.714 31.533 12.986 1.00 39.13C
ATOM12591CG2ILEL119 2.184 30.644 11.672 1.0038.43C
ATOM12592C ILEL119 -0.114 32.640 11.655 1.00 38.22C
ATOM12593O ILEL119 -0.576 32.610 12.793 1.00 39.28O
ATOM12594N HIS L120 -0.855 32.322 10.600 1.0036.48N
ATOM12595CA HIS L120 -2.284 31.990 10.756 1.00 34.79C
ATOM12596CB HIS L120 -3.092 32.449 9.538 1.00 34.77C
ATOM12597CG HIS L120 -3.216 33.938 9.359 1.00 33.68C
ATOM12598NDl HIS L120 -4.380 34.527 8.909 1.0032.18N
ATOM12599CEl HIS L120 -4.200 35.831 8.793 1.0033.74C
ATOM12600NE2HISL120 -2.961 36.114 9.160 1.0033.46N
ATOM12601CD2HISL120 -2.319 34.944 9.500 1.0033.92C
ATOM12602C HIS L120 -2.436 30.472 10.870 1.00 33.95C
ATOM12603O fflS L120 -1.888 29.741 10.045 1.00 33.99O
ATOM12604N ARGL121 -3.141 29.992 11.887 1.00 32.80N
ATOM12605CA ARG L121 -3.598 28.591 11.918 1.00 32.97C
ATOM12606CB ARGL121 -4.096 28.229 13.323 1.00 32.84C
ATOM12607CG ARGL121 -3.051 28.381 14.429 1.0031.74C
ATOM12608CD ARG L121 -3.690 28.299 15.826 1.00 32.27C
ATOM12609NE ARG L121 -4.523 29.472 16.094 1.00 30.79N
ATOM12610CZ ARGL121 -5.391 29.595 17.100 1.00 32.42C
ATOM12611NHl ARG L121 -5.556 28.615 17.982 1.00 31.28N
ATOM12612NH2ARGL121 -6.109 30.712 17.223 1.0031.85N
ATOM12613C ARGL121 -4.747 28.374 10.906 1.00 32.75C
ATOM12614O ARGL121 -5.628 29.209 10.821 1.00 33.82O
ATOM12615N LEUL122 -4.764 27.273 10.152 1.0032.47N
ATOM12616CA LEUL122 -5.974 26.948 9.358 1.0031.95C
[0528]ATOM12617CB LEU L122 -5.704 26.915 7.840 1.0031.72CATOM12618CG LEU L122 -5.605 28.239 7.039 1.00 32.00C
ATOM12619CDl LEU L122 -6.86729.099 7.1291.00 30.69C
ATOM12620CD2LEUL122 -4.34529.088 7.3661.00 32.89C
ATOM12621C LEU L122 -6.64825.671 9.8331.0031.06C
ATOM12622O LEUL122 -6.15324.579 9.6211.0031.52O
ATOM12623N VALL123 -7.81525.826 10.4321.00 30.62N ATOM12624CA VALL123 -8.437 24.768 11.207 1.0029.21C
ATOM12625CB VALL123 -8.974 25.343 12.536 1.0029.44C
ATOM12626CGl VALL123 -9.41424.212 13.4671.0028.82C
ATOM12627CG2 VALL123 -7.90326.257 13.2141.0028.59C
ATOM12628C VALL123 -9.56524.023 10.4531.0028.74C
ATOM12629O VALL123-10.52624.633 9.9801.0028.63O
ATOM12630N PHE L124 -9.41722.700 10.3641.0028.11N
ATOM12631CA PHEL124-10.44821.788 9.8311.00 27.58C
ATOM12632CB PHEL124 -9.82720.744 8.8811.0026.62C
ATOM12633CG PHE L124 -9.099 21.349 7.7301.0025.51C
ATOM12634CDl PHEL124 -7.82621.957 7.9231.00 20.71C
ATOM12635CEl PHEL124 -7.17122.549 6.8671.00 19.30C
ATOM12636CZ PHEL124 -7.74122.542 5.5701.0022.97C
ATOM12637CE2PHEL124 -8.99321.951 5.3641.0020.64C
ATOM12638CD2PHEL124 -9.67721.363 6.4621.0020.36C
ATOM12639C PHEL 124-11.15221.066 10.9631.0027.23C
ATOM12640O PHEL124-10.50420.421 11.7901.00 25.93O
ATOM12641N VALL125-12.48321.176 10.9601.00 27.40N
ATOM12642CA VALL125-13.33820.570 11.9551.00 27.41C
ATOM12643CB VALL125-14.01221.638 12.8861.0028.00C
ATOM12644CGl VALL125-14.74420.958 14.0301.0026.18C
ATOM12645CG2 VALL125-12.97022.663 13.4481.0026.61C
ATOM12646C VALL125-14.39119.680 11.2831.00 28.12C
ATOM12647O VALL125-15.14020.106 10.3991.0027.88O
ATOM12648N LEUL126-14.42518.423 11.7171.0028.71N
ATOM12649CA LEUL 126-15.40117.463 11.2211.0028.92C
ATOM12650CB LEUL126-14.72016.170 10.7601.0028.55C
ATOM12651CG LEUL 126-15.57215.333 9.7881.0026.84C
ATOM12652CDl LEUL 126-15.51215.923 8.3661.0024.38C
ATOM12653CD2 LEUL126-15.13213.880 9.8051.00 24.92C
ATOM12654C LEUL126-16.43417.158 12.2831.0029.65C
ATOM12655O LEUL 126-16.07116.900 13.4561.00 30.14O
ATOM12656N PHEL127-17.69617.219 11.8531.0029.76N
ATOM12657CA PHEL127-18.88716.874 12.6411.0031.35C
ATOM12658CB PHEL 127-19.85018.073 12.7731.00 30.83C
ATOM12659CG PHEL 127-19.25619.250 13.4801.0030.93C
ATOM12660CDl PHEL127-19.37119.376 14.8561.00 30.76C
[0529]
[0530]ATOM12705ΝΉ2 ARGL132-28.011 13.0920.270 1.00 53.31NATOM12706C ARGL132-30.103 16.1736.205 1.0048.61C
ATOM12707O ARG L132 -31.292 15.9476.433 1.0048.52O
ATOM12708N GLNL133 -29.547 17.3676.400 1.0049.01N
ATOM12709CA GLNL133 -30.394 18.5206.678 1.0049.20C
ATOM12710CB GLNL133 -30.510 18.7808.187 1.0049.65C
ATOM12711CG GLNL133 -29.572 19.8228.767 1.0050.69C·ATOM12712CD GLNL133-28.217 19.2739.037 1.00 52.12C
ATOM12713OEl GLNL133-27.293 19.4558.239 1.00 54.32O
ATOM12714NE2 GLNL133-28.069 18.59210.168 1.00 53.09N
ATOM12715C GLNL133-29.986 19.7645.886 1.0048.90C
ATOM12716O GLNL133-28.908 19.7995.288 1.0049.21O
ATOM12717N THRL 134-30.862 20.7685.874 1.0048.17N
ATOM12718CA THRL134 -30.603 22.0235.182 1.0047.50C
ATOM12719CB THRL134 -31.922 22.7214.815 1.0047.86C
ATOM12720OGl THRL134 -32.727 21.8314.014 1.0048.58O
ATOM12721CG2THRL 134-31.649 24.0034.044 1.0047.98C
ATOM12722C THRL134-29.685 22.9685.981 1.00 46.92C
ATOM12723O THRL 134-29.920 23.2627.164 1.00 46.34O
ATOM12724N VALL135-28.627 23.4275.309 1.0046.33N
ATOM12725CA VALL135-27.651 24.3525.877 1.0045.17C
ATOM12726CB VALL135-26.255 23.6916.005 1.0044.77C
ATOM12727CGl VALL135-25.223 24.6816.525 1.0045.51C
ATOM12728CG2 VALL135-26.315 22.4606.896 1.0044.34C
ATOM12729C VALL135-27.561 25.5314.932 1.0044.88C
ATOM12730O VALL135-27.348 25.3423.733 1.0044.40O
ATOM12731N TYRL136 -27.747 26.7375.463 1.0044.76N
ATOM12732CA TYRL136-27.455 27.9494.722 1.0044.78C
ATOM12733CB TYRL 136-28.476 29.0415.009 1.00 45.08C
ATOM12734CG TYRL136-29.870 28.6214.647 1.0045.67C
ATOM12735CDl TYRL136 -30.875 28.6025.612 1.0045.96C
ATOM12736CEl TYRL136-32.171 28.1825.294 1.0046.13C
ATOM12737CZ TYRL136-32.464 27.7804.004 1.0045.44C
ATOM12738OH TYRL136 -33.740 27.3693.716 1.0045.42O
ATOM12739CE2 TYRL 136-31.475 27.7793.012 1.0046.33C
ATOM12740CD2 TYR L136-30.180 28.1933.343 1.0045.29C
ATOM12741C TYRL136 -26.025 28.4354.983 1.0045.28C
ATOM12742O TYRL 136-25.443 28.1866.045 1.0045.04O
ATOM12743N ALAL137 -25.506 29.1603.993 1.00 45.69N
ATOM12744CA ALAL 137-24.091 29.4373.800 1.0046.21C
ATOM12745CB ALAL 137-23.757 29.1852.332 1.0046.48C
ATOM12746C ALAL137 -23.695 30.8724.154 1.0046.55C
ATOM12747O ALAL137 -23.528 31.7043.220 1.00 47.36O
ATOM12748N PRO L138 -23.426 31.1505.457 1.00 45.63N
[0531]ATOM12749CA PROL138-23.380 32.493 6.056 1.0044.91CATOM 12750CB PRO L138 -22.321 32.341 7.166 1.0044.77C
ATOM12751CG PROL 138-21.904 30.876 7.135 1.0044.76C
ATOM12752CD PROL138-22.979 30.147 6.432 1.0045.20C ATOM12753C PROL138-22.996 33.5995.062 1.0044.13C
ATOM12754O PROL 138-22.052 33.4144.284 1.00 44.29O
ATOM12755N GLYL 139-23.716 34.7305.104 1.0043.10N
ATOM12756CA GLYL139-23.621 35.802 4.093 1.0041.70C
ATOM12757C GLYL139-22.328 36.6154.031 1.0040.90C
ATOM12758O GLYL 139-22.110 37.3923.078 1.0040.64O
ATOM12759N TRPL140 -21.483 36.4665.050 1.0040.13N
ATOM12760CA TRPL140-20.096 36.9584.991 1.00 39.03C
ATOM12761CB TRPL 140-19.933 38.2445.798 1.0040.27C
ATOM12762CG TRPL140-20.480 38.0697.144 1.00 40.66C
ATOM12763CDl TRPL 140-19.808 37.6638.241 1.0040.94C
ATOM12764NEl TRPL140 -20.668 37.5559.308 1.00 43.80N
ATOM12765CE2 TRPL 140-21.933 37.8918.897 1.0044.04C
ATOM12766CD2 TRP L140-21.851 38.2117.525 1.00 42.33C
ATOM12767CE3 TRPL140-23.022 38.5856.839 1.0043.87C
ATOM12768CZ3 TRPL140-24.246 38.6217.548 1.00 43.10C
ATOM12769CH2 TRP L 140-24.292 38.2908.920 1.0043.08C
ATOM12770CZ2 TRP L140-23.149 37.9249.613 1.00 44.08C
ATOM12771C TRPL140-19.210 35.8325.525 1.00 37.92C
ATOM12772O TRPL140-19.723 34.8746.117 1.00 37.69O
ATOM12773N ARGL141-17.901 35.9285.293 1.00 36.20N
ATOM12774CA ARG L141 -16.942 34.930 5.764 1.00 34.44C
ATOM12775CB ARGL141 -15.799 34.768 4.755 1.0034.30C
ATOM12776CG ARGL141 -16.158 33.947 3.514 1.00 32.33C
ATOM12777CD ARGL141-14.919 33.742 2.665 1.0031.60C
ATOM12778NE ARG L141 -15.214 33.353 1.290 1.0028.07N
ATOM12779CZ ARGL141-15.078 32.122 0.802 1.0028.75C
ATOM12780NHl ARGL141-14.666 31.142 1.584 1.0026.88N
ATOM12781NH2 ARGL141-15.361 31.868-0.486 1.0027.15N
ATOM12782C ARGL141-16.375 35.2317.151 1.00 33.83C
ATOM12783O ARGL141-16.189 34.3267.952 1.00 33.85O
ATOM12784N GLNL142-16.116 36.5027.436 1.00 33.30N
ATOM12785CA GLNL142-15.658 36.947 8.774 1.00 32.95C
ATOM12786CB GLNL142-15.225 38.422 8.732 1.00 33.22C
ATOM12787CG GLNL142-16.378 39.395 8.799 1.0033.54C
ATOM12788CD GLNL142-16.832 39.869 7.443 1.00 34.37C
ATOM12789OEl GLNL 142-16.889 39.0966.468 1.0038.40O
ATOM12790NE2 GLNL142-17.180 41.1467.366 1.0032.24N
ATOM12791C GLNL 142-16.657 36.7409.945 1.00 32.73C
ATOM12792O GLNL142-17.873 36.6639.754 1.00 30.88O
[0532]ATOM12793N ASNL143-16.09136.66711.1531.0031.91NATOM12794CA ASNL143-16.82136.53712.4191.0031.97 C
ATOM12795CB ASNL143-17.42137.87012.8841.0031.31C
ATOM12796CG ASNL143-16.426 38.98112.8501.00 34.71 C
ATOM12797ODl ASNL143-16.51939.86011.9981.00 38.96O
ATOM12798ND2 ASNL143-15.43238.94313.7551.00 33.36N
ATOM12799C ASNL143-17.84135.39912.4601.0031.79C
ATOM12800O ASNL143-18.89435.50113.1131.0031.02O
ATOM12801N PHEL 144-17.48334.32911.7371.0031.36N
ATOM12802CA PHEL144-18.02333.00511.9041.0029.37C
ATOM12803CB PHEL 144-17.42132.05610.8561.0028.98C
ATOM12804CG PHEL144-18.18330.74510.6801.0024.45C
ATOM12805CDl PHEL 144-17.66429.56811.1411.0019.22C
ATOM12806CEl PHEL144-18.35828.33610.9561.0023.97C
ATOM12807CZ PHEL144-19.59328.30210.3291.0022.16C
ATOM12808CE2 PHE L144-20.15829.4979.8741.0020.46C·
ATOM12809CD2 PHE L 144-19.43330.71910.0531.0025.81C
ATOM12810C PHEL144-17.69332.49413.2951.00 30.16C
ATOM12811O PHEL 144-16.68032.86113.9231.0029.90O
ATOM12812N ASNL145-18.56631.62113.7581.00 30.48N
ATOM12813CA ASNL145-18.390 30.93015.0121.00 31.08C
ATOM12814CB ASNL145-19.20631.61716.0781.00 30.94C
ATOM12815CG ASNL145-18.92731.08517.4091.00 30.72C
ATOM12816ODl ASNL145-19.52030.08817.8111.0031.89O
ATOM12817ND2 ASNL145-18.01831.74418.1361.00 27.18N
ATOM12818C ASNL145-18.85329.50514.8381.0031.58C
ATOM12819O ASNL145 -20.04329.24014.6021.00 32.41O
ATOM12820N THRL 146-17.89328.59314.9221.00 32.30N
ATOM12821CA THRL146-18.13727.16814.7381.00 32.65C
ATOM12822CB THRL146-16.79226.44314.5251.0032.17C
ATOM12823OGl THRL146-16.22826.91813.2941.0031.44O
ATOM12824CG2 THRL 146-16.95624.93314.4701.00 32.88C
ATOM12825C THRL146-19.00226.56315.8501.00 33.20C
ATOM12826O THRL 146-19.92425.76115.5861.0032.54O
ATOM12827N LYSL 147-18.69726.95417.0841.00 34.21N
ATOM12828CA LYS L147-19.51826.60318.2521.00 35.36C
ATOM12829CB LYS L 147-19.07027.41019.4711.00 35.35C
ATOM12830CG LYSL 147-17.57727.94519.4281.00 38.23C
ATOM12831CD LYSL 147-17.45629.44419.9111.00 36.43C
ATOM12832CE LYS L147-16.01929.87820.2601.00 35.34C
ATOM12833NZ LYS L147-15.41229.04421.3631.00 35.06N
ATOM12834C LYS L147-21.03126.81317.9881.00 35.21C
ATOM12835O LYS L147 -21.82825.89318.1371.00 34.15O
ATOM12836N ASPL148 -21.39228.03217.5841.00 36.40N
[0533]ATOM12837CA ASPL148-22.771 28.43517.327 1.00 37.19CATOM12838CB ASPL148 -22.855 29.96417.214 1.00 37.87C
ATOM12839CG ASPL148 -22.536 30.68018.527 1.0040.69C
ATOM12840ODl ASP L148 -22.811 30.12019.621 1.0042.01O
ATOM12841OD2 ASPL148-22.010 31.81918.460 1.0043.07O
ATOM12842C ASPL148 -23.369 27.77916.070 1.00 37.47C
ATOM12843O ASPL148 -24.558 27.46416.035 1.00 37.57O
ATOM12844N PHEL149-22.540 27.59715.037 1.00 37.45N·ATOM12845CA PHEL149 -22.930 26.87513.825 1.00 37.04C
ATOM12846CB PHE L149 -21.792 26.95612.787 1.00 36.73C
ATOM12847CG PHE L149 -22.053 26.16411.524 1.00 36.98C
ATOM12848CDl PHE L149 -22.886 26.67010.518 1.00 36.35C
ATOM12849CEl PHEL149-23.123 25.9319.345 1.00 35.81C
ATOM12850CZ PHEL149-22.542 24.6789.179 1.00 33.87C
ATOM12851CE2 PHEL 149-21.713 24.17310.156 1.0035.81C
ATOM12852CD2 PHE L 149-21.468 24.91411.336 1.0036.62C
ATOM12853C PHE L149 -23.314 25.40514.132 1.0037.31C
ATOM12854O PHEL149 -24.371 24.90213.685 1.0037.21O
ATOM12855N ALAL150 -22.448 24.73714.892 1.0036.95N
ATOM12856CA ALAL150 -22.649 23.36015.322 1.00 37.33C
ATOM12857CB ALAL150-21.450 22.89416.138 1.00 36.99C
ATOM12858C ALAL150-23.904 23.24016.164 1.0037.56C
ATOM12859O ALAL150 -24.595 22.23416.121 1.00 38.03O
ATOM12860N GLUL151 -24.168 24.27616.948 1.0037.74N
ATOM12861CA GLUL151 -25.332 24.34317.807 1.00 37.73C
ATOM12862CB GLUL151-25.110 25.41518.856 1.00 37.87C
ATOM12863CG GLUL151 -26.299 25.83319.687 1.0042.62C
ATOM12864CD GLUL151 -25.874 26.930 20.660 1.0049.21C
ATOM12865OEl GLUL151 -25.007 26.63321.513 1.00 52.01O
ATOM12866OE2 GLUL151 -26.366 28.08620.564 1.00 50.99O
ATOM12867C GLUL151 -26.590 24.58916.985 1.00 36.95C
ATOM12868O GLUL151 -27.563 23.85917.152 1.0036.92O
ATOM12869N LEUL152 -26.566 25.58716.092 1.00 35.68N
ATOM12870CA LEUL152 -27.713 25.87115.222 1.00 35.10C
ATOM12871CB LEUL152-27.408 27.06414.305 1.0035.36C
ATOM12872CG LEUL152 -28.317 27.38013.097 1.00 35.41C
ATOM12873CDl LEUL152 -29.751 27.68413.516 1.0035.49C
ATOM12874CD2 LEU L 152-27.771 28.54512.288 1.00 33.92C
ATOM12875C LEUL152 -28.147 24.63914.384 1.00 35.16C
ATOM12876O LEUL152 -29.336 24.42914.100 1.0035.39O
ATOM12877N TYRL153 -27.165 23.84113.996 1.0034.23N
ATOM12878CA TYRL153 -27.387 22.74213.109 1.00 34.11C
ATOM12879CB TYRL153 -26.436 22.84511.911 1.0032.37C
ATOM12880CG TYRL153 -26.857 23.95410.988 1.00 31.10C
[0534]ATOM12881CDl TYRL153 -28.01923.83910.2241.0027.61CATOM12882CEl TYRL153 -28.43424.8619.4081.0027.80C
ATOM12883CZ TYRL153 -27.70326.0129.3141.0027.66C
ATOM12884OH TYRL153-28.15027.013 8.4881.0028.54 O
ATOM12885CE2 TYRL153-26.54526.16410.0541.0027.37C
ATOM12886CD2 TYRL153-26.12825.12910.8931.0027.71C
ATOM12887C TYRL153 -27.30221.39113.8031.00 35.26C
ATOM12888O TYRL153 -27.24620.37313.1171.00 35.58O
ATOM12889N ASNL154-27.28721.37415.1481.0035.81N
ATOM12890CA ASNL154-27.33120.10915.8981.0036.83C
ATOM12891CB ASNL154-28.70019.42315.7021.00 37.30C
ATOM12892CG ASNL154 -29.85220.28716.1761.00 39.35C
ATOM12893ODl ASNL 154-30.14720.34017.3781.0041.86O
ATOM12894ND2ASN L 154-30.50620.97015.2411.00 38.82N
ATOM12895C ASNL154 -26.25619.12215.4701.0036.29C
ATOM12896O ASNL154-26.54217.93815.2491.00 36.41O
ATOM12897N LEUL155-25.03019.61215.3281.0035.66N
ATOM12898CA LEUL155-23.95218.79114.7871.00 35.00C
ATOM12899CB LEUL155-23.00119.61913.9271.00 34.68C
ATOM12900CG LEUL155-23.58620.24812.6761.0033.11C
ATOM12901CDl LEUL155-22.54321.14412.0701.0031.98C
ATOM12902CD2 LEU L155-24.07019.16611.6901.00 33.30C
ATOM12903C LEUL155 -23.23118.13115.9381.0034.68C
ATOM12904O LEUL155-22.44217.21615.7451.0034.63O
ATOM12905N GLYL156 -23.56618.59917.1311.0034.34N
ATOM12906CA GLYL156-23.06118.07818.3801.00 34.33C
ATOM12907C GLYL156 -21.66318.58518.5821.00 33.93C
ATOM12908O GLYL156 -21.35019.74818.3001.0033.68O
ATOM12909N SERL 157-20.81217.67719.0311.00 33.75N
ATOM12910CA SERL 157-19.40117.95919.1671.0033.94C
ATOM12911CB SERL157-18.87917.28220.4361.00 33.97C
ATOM12912OG SERL157-19.71617.64321.4961.00 34.65O
ATOM12913C SERL 157-18.59317.50417.9361.00 33.80C
ATOM12914O SERL 157-19.04516.64117.1321.00 33.44O
ATOM12915N PROL158-17.39018.07417.7811.0033.58N
ATOM12916CA PROL158-16.57217.57616.6891.00 33.66C
ATOM12917CB PRO L158-15.31018.45616.7471.0034.35C
ATOM12918CG PROL158-15.61919.56817.6721.00 33.33C
ATOM12919CD PRO L158-16.71919.12918.5631.00 33.36C
ATOM12920C PROL158-16.23016.09016.8881.00 33.41C
ATOM12921O PROL158-16.24115.56918.0191.0034.23O
ATOM12922N VALL 159-15.95315.41015.7881.00 32.12N
ATOM12923CA VALL 159-15.60514.00315.8281.0031.10C
ATOM12924CB VALL 159-16.54613.12614.9041.0030.22C
[0535]ATOM12925CGl VALL159-17.908 13.06915.470 1.0029.91CATOM12926CG2 VALL159-16.621 13.66913.525 1.0028.84C
ATOM12927C YALL159-14.158 13.90015.398 1.00 30.96C
ATOM12928O VALL159-13.503 12.89915.625 1.00 30.93O
ATOM12929N ALAL160-13.684 14.96414.763 1.0031.81N
ATOM12930CA ALAL160-12.306 15.11014.305 1.00 32.04C
ATOM12931CB ALAL160 -12.066 14.26113.039 1.00 32.64C
ATOM12932C ALAL160-11.936 16.57814.041 1.0031.98C ATOM12933O ALAL160-12.786 17.41713.743 1.0031.18O
ATOM12934N ALAL161-10.641 16.86514.130 1.00 32.43N
ATOM12935CA ALAL161 -10.124 18.20213.891 1.00 32.50C
ATOM12936CB ALAL161 -10.526 19.13715.029 1.00 32.27C
ATOM12937C ALAL161 -8.592 18.17313.682 1.0032.55C
ATOM12938O ALAL161 -7.908 17.32314.242 1.00 32.20O
ATOM12939N VALL162 -8.089 19.09512.849 1.00 33.14N
ATOM12940CA VALL162 -6.662 19.18812.442 1.00 32.39C
ATOM12941CB VALL162 -6.254 18.01211.436 1.00 32.42C
ATOM12942CGl VALL162 -6.740 18.25710.005 1.0031.59C
ATOM12943CG2 VALL162 -4.753 17.70911.473 1.00 30.76C
ATOM12944C VALL162 -6.398 20.61011.888 1.00 32.53C
ATOM12945O VALL162 -7.285 21.21911.281 1.0032.43O
ATOM12946N TYRL163 -5.212 21.16812.150 1.00 32.05N
ATOM12947CA TYRL163 -4.879 22.49711.660 1.00 30.91C
ATOM12948CB TYRL163 -4.962 23.54212.774 1.0031.05C
ATOM12949CG TYRL163 -3.803 23.53513.778 1.00 30.00C
ATOM12950CDl TYRL163 -2.792 24.49313.719 1.0031.18C
ATOM12951CEl TYRL163 -1.719 24.50114.669 1.0029.88C
ATOM12952CZ TYRL163 -1.697 23.53515.662 1.0031.08C
ATOM12953OH TYRL163 -0.692 23.49116.588 1.00 32.55 O
ATOM12954CE2 TYRL163 -2.712 22.58615.747 1.00 32.06C
ATOM12955CD2TYRL163 -3.753 22.59214.803 1.0030.07C
ATOM12956C TYRL163 -3.495 22.48411.056 1.0031.22C
ATOM12957O TYRL163 -2.694 21.62611.395 1.00 32.19O
ATOM12958N PHEL164 -3.217 23.41510.148 1.0031.09N
ATOM12959CA PHE L164 -1.856 23.6609.730 1.0031.43C
ATOM12960CB PHEL164 -1.605 23.2288.255 1.0031.76C
ATOM12961CG PHE L164 -2.322 24.0777.207 1.00 32.44C
ATOM12962CDl PHEL164 -3.555 23.6716.686 1.00 32.80C
ATOM12963CEl PHE L164 -4.211 24.4405.713 1.00 30.59C
ATOM12964CZ PHEL164 -3.646 25.6065.273 1.0029.63C
ATOM12965CE2PHEL164 -2.417 26.0255.775 1.00 30.03C
ATOM12966CD2 PHEL164 -1.754 25.2636.724 1.0030.65C
ATOM12967C PHE L164 -1.485 25.11710.037 1.00 31.64C
ATOM12968O PHEL164 -2.350 25.94910.286 1.0031.40O
[0536]ATOM12969N ASN L165-0.19225.41510.087 1.00 32.07NATOM12970CA ASNL1650.24926.79810.213 1.00 32.28C
ATOM12971CB ASNL1651.39426.91111.240 1.00 32.70C
ATOM12972CG ASNL1650.89026.89412.673 1.0034.01C
ATOM12973ODl ASN L1651.40026.16313.509 1.00 37.38O
ATOM12974ND2ASNL165-0.12227.69412.958 1.00 33.11N
ATOM12975C ASN L1650.62327.4058.857 1.0031.97C
ATOM12976O ASN L1651.07526.7177.968 1.00 30.94O·ATOM12977N SERL1660.41028.6938.674 1.0033.48N
ATOM12978CA SERL1660.82329.2817.411 1.00 35.07C
ATOM12979CB SERL166-0.22629.0376.313 1.0035.10C
ATOM12980OG SER L1660.26429.4285.030 1.00 33.79O
ATOM12981C SERL1661.09430.7647.544 1.0036.59C
ATOM12982O SERL1660.45431.4408.323 1.0036.95O
ATOM12983N GLNL1672.02031.2796.743 1.00 38.83N
ATOM12984CA GLNL1672.30532.7126.766 1.0041.03C
ATOM12985CB GLNL1673.40033.0377.795 1.0040.49C
ATOM12986CG GLNL1674.76332.4677.469 1.0041.59C
ATOM12987CD GLNL1675.74432.6788.614 1.0041.70C
ATOM12988OEl GLNL1675.70733.7059.297 1.0042.37O
ATOM12989NE2 GLNL1676.60631.6998.839 1.00 42.05N
ATOM12990C GLN L1672.70033.2065.397 1.00 42.11C
ATOM12991O GLN L1672.94032.4164.507 1.0041.16O
ATOM12992N ARGL1682.76334.5265.245 1.0045.20N
ATOM12993CA ARGL1683.06735.1323.954 1.00 47.85C
ATOM12994CB ARGL1683.09336.6464.054 1.0047.85C
ATOM12995CG ARG L1682.39237.3182.896 1.0048.86C
ATOM12996CD ARG L1683.32838.2732.194 1.0051.87C
ATOM12997NE ARGL1684.36538.7593.092 1.00 53.92N
ATOM12998CZ ARGL1684.28639.8903.780 1.00 57.31C
ATOM12999NHl ARG L1683.20240.6703.674 1.00 57.52N
ATOM13000NH2ARGL1685.29740.2404.576 1.00 57.87N
ATOM13001C ARGL1684.40734.6183.509 1.0049.55C
ATOM13002O ARGL1685.36734.6704.274 1.0049.56O
ATOM13003N GLUL1694.47234.0772.299 1.00 52.00N
ATOM13004CA GLUL1695.69033.3801.905 1.00 55.34C
ATOM13005CB GLUL1695.42632.1041.084 1.00 55.31C
ATOM13006CG GLUL1694.62432.271-0.195 1.00 56.73C
ATOM13007CD GLUL1694.51230.967-0.959 1.00 57.10C
ATOM13008OEl GLUL1695.51330.554-1.600 1.0060.49O
ATOM13009OE2GLUL1693.42630.355-0.920 1.0057.77O
ATOM13010C GLUL1696.73634.2721.254 1.00 56.55C
ATOM13011O GLU L1697.94434.1271.547 1.00 57.60O
ATOM13012N ALAL1706.27935.1920.399 1.00 57.55N
[0537]ATOM13013CAALAL1707.175 36.062 -0.354 1.00 57.99CATOM13014 CBALAL1706.410 37.265 -0.929 1.00 58.61C
ATOM13015CALAL1708.351 36.508 0.523 1.00 58.33C
ATOM13016 OALAL1708.176 36.968 1.660 1.00 58.14O
ATOM13017 OXTALAL1709.508 36.368 0.126 1.00 58.26O TER
ATOM13018OHOHMI19.982 6.426 -5.674 1.00 14.89O
ATOM13019OHOHM221.945 7.860 -4.637 1.0014.81O
ATOM13020OHOHM326.198 7.575 -5.259 1.0023.47O·
ATOM13021OHOHM428.047 11.060-10.555 1.0033.93O
ATOM13022OHOHM524.595 13.351 -9.777 1.00 34.27 O
ATOM13023OHOHM630.053 14.909-15.973 1.00 33.81O
ATOM13024OHOHM715.933 8.565 -23.665 1.0029.25O
ATOM13025OHOHM817.634 21.409-22.467 1.00 31.38O
ATOM13026OHOHM916.160 20.961 -25.719 1.0023.85O
ATOM13027OHOHM1017.563 23.215 -9.910 1.00 60.30 O
ATOM13028OHOHM1125.463 22.002 -5.863 1.0015.86 O
ATOM13029OHOHM1222.452 29.474-10.559 1.0020.78O
ATOM13030OHOHM13-10.013 34.430-15.686 1.0018.23O
ATOM13031OHOHM14 -30.885 26.980-18.029 1.0028.13O
ATOM13032OHOHM1524.237 -33.076 -1.100 1.00 29.21O
ATOM13033OHOHM16 4.295 -34.345 16.744 1.0022.61O
ATOM13034OHOHM17 4.882 -31.245 22.208 1.0017.48O
ATOM13035OHOHM18-4.751 -32.423 46.119 1.0023.86O
ATOM13036OHOHM1916.372 -32.658 18.289 1.0045.82O
ATOM13037OHOHM2026.330-12.310 19.935 1.0031.75O
ATOM13038OHOHM2115.305 -3.634-18.408 1.00 44.23O
ATOM13039OHOHM2222.020 -37.315 14.654 1.00 38.07O
ATOM13040OHOHM23-1.510-33.857 -0.976 1.00 33.06O
ATOM13041OHOHM24 5.443 -7.670 17.600 1.0031.27O
ATOM13042OHOHM2519.514-47.774 1.300 1.00 30.89O
ATOM13043OHOHM2620.466 -23.573 20.350 1.0026.63O
ATOM13044OHOHM27-3.012-33.494 24.736 1.00 33.38O
ATOM13045OHOHM28-7.952 34.151 6.829 1.0031.53O
ATOM13046OHOHM2929.747 18.644 -1.965 1.0029.33 O
ATOM13047OHOHM30 4.991 37.024-29.118 1.00 34.21O
ATOM13048OHOHM31 -32.446 -9.360 -9.575 1.00 33.69O
ATOM13049OHOHM32 9.437 -12.408 35.901 1.0022.96O
ATOM13050OHOHM3343.878 17.519 16.269 1.0042.25 O
ATOM13051OHOHM34-0.440-20.100 25.350 1.00 32.81O
ATOM13052OHOHM35-0.140-15.022 32.771 1.00 39.42O
ATOM13053OHOHM3612.555-41.565 31.780 1.0031.20O
ATOM13054OHOHM37 7.019-53.029 -4.412 1.0041.29O
ATOM13055OHOHM38-21.770 51.113-11.766 1.0036.20O
[0538]ATOM13056OHOHM39 -8.718 32.426 -31.736 1.0044.42OATOM13057OHOHM40-25.320 -2.346 -29.687 1.0023.18O
ATOM13058OHOHM41 4.801 -42.825 14.862 1.0038.28O
ATOM13059OHOHM42 21.325 21.012 -4.856 1.0025.08O
ATOM13060OIIOHM43 7.869-11.597 6.658 1.0045.02O
ATOM13061OHOHM44 20.346 4.958 2.451 1.00 36.30O
ATOM13062OHOHM45 -3.146 -23.094-21.681 1.0029.55O
ATOM13063OHOHM46 15.556 9.404-19.010 1.0034.62O
ATOM13064OHOHM47 10.623 19.720-42.385 1.0027.42O
ATOM13065OHOHM48 -2.996 17.145 -36.980 1.0037.76O
ATOM13066OHOHM49 -8.895 41.329 -2.536 1.0029.60O
ATOM13067OHOHM50 22.381 43.780 -2.013 1.00 30.27O
ATOM13068OHOHM51 -9.800 -31.257 25.839 1.0023.70O
ATOM13069OHOHM52 -3.158 41.558 -9.619 1.00 34.44O
ATOM13070OHOHM53 -4.449 29.694-35.211 1.0042.04O
ATOM13071OHOHM54 -23.578 26.793 -7.349 1.00 22.46O
ATOM13072OHOHM55 -4.910-36.543 20.887 1.00 36.53O
ATOM13073OHOHM56 1.428-48.922-12.964 1.0021.61O
ATOM13074OHOHM57 11.107 29.978 -9.352 1.0044.26O
ATOM13075OHOHM58 21.608 -42.793-17.050 1.0031.68O
ATOM13076OHOHM59-17.400 44.503 -25.970 1.00 33.25O
ATOM13077OHOHM60 -24.530 9.419-19.978 1.0045.36O
ATOM13078OHOHM61 23.323 -18.407 8.102 1.00 33.38O
ATOM13079OHOHM62-13.446 -26.326-18.405 1.00 35.93O
ATOM13080OHOHM63 -8.401 14.568 -19.708 1.0046.64O
ATOM13081OHOHM64-15.830 21.997 -26.662 1.00 27.79O
ATOM13082OHOHM65 17.308 -0.479 25.821 1.0047.21O
ATOM13083OHOHM66 16.863 -16.085 14.484 1.0027.71O
ATOM13084OHOHM67-14.178 20.087-13.053 1.00 35.49O
ATOM13085OHOHM68 17.729-19.670 28.133 1.0023.07O
ATOM13086OHOHM69 -21.397 14.744 19.995 1.0040.60O
ATOM13087OHOHM70 -1.120 42.699 9.679 1.0031.77O
ATOM13088OHOHM71-11.636 18.111 -1.915 1.00 24.17O
ATOM13089OHOHM72 16.776 12.131 -14.076 1.00 58.51O
ATOM13090OHOHM73 5.534 18.463 -36.715 1.00 36.96O
ATOM13091OHOHM74 13.125 -22.700-13.217 1.0040.48O
ATOM13092OHOHM75 2.528 35.935 -34.773 1.00 36.00O
ATOM13093OHOHM76 26.877 -43.833 -3.430 1.0024.69O
ATOM13094OHOHM77 -38.025 41.066-15.902 1.0044.13O
ATOM13095OHOHM78 9.691 -9.751 19.345 1.0043.97O
ATOM13096OHOHM79 30.878 37.399-14.450 1.0044.74O
ATOM13097OHOHM80-12.178 44.350 -9.552 1.0040.00O
ATOM13098OHOHM81 2.834 -39.270 28.041 1.0022.92O
ATOM13099OHOHM82 -29.696-29.530 5.879 1.0049.86O
[0539]ATOM13100OHOHM 83-17.118 14.381 21.906 1.0028.12OATOM〗310]OHOHM 84 -9.129 32.466 -3.527 1.00 30.04O
ATOM13102OHOHM 85 18.607 -30.608 40.036 1.00 27.89O
ATOM13103OHOHM 86 -9.263 40.091 -9.988 1.00 33.42O
ATOM13104 OHOHM 87-30.551 36.712 -25.683 1.0024.80O
ATOM13105OHOHM 88 -9.763 -47.489 -12.026 1.00 39.63O
ATOM13106OHOHM 89-23.440 51.408 -7.328 1.0031.15O
ATOM13107OHOHM 90 -0.174-25.611 15.167 1.00 33.82O· ATOM13108OHOHM 91 -13.026 0.562 15.097 1.00 50.88O
ATOM13109OHOHM 92 22.527 -2.511 7.539 1.00 27.39O
ATOM13110OHOHM 93 14.588 23.227-19.575 1.0015.20O
ATOM13111OHOHM 94-11.177 -22.485 32.237 1.0031.74O
ATOM13112OHOHM 95 23.864-20.331 32.408 1.00 26.40O
ATOM13113OHOHM 96 0.093 -47.129 10.592 1.00 41.09O
ATOM13114OHOHM 97 7.780 28.518-32.871 1.0026.26O
ATOM13115OHOHM 98-12.146-14.991 39.064 1.0041.06O
ATOM13116OHOHM 99-16.787 37.510 3.148 1.00 29.82O
ATOM13117OHOHM100-16.159 19.209-16.949 1.0040.68O
ATOM13118OHOHM101 -3.215 14.505 30.107 1.0046.70O
ATOM13119OHOH M102 6.765 -39.317 28.017 1.00 17.64O
ATOM13120OHOHM103-18.853 -26.771 21.206 1.0021.99O
ATOM13121OHOHM104 -5.677 -32.027 2.262 1.00 55.69O
ATOM13122OHOHM105 5.329 32.229 -28.947 1.0024.05O
ATOM13123OHOH M106 19.011 -9.831 21.422 1.00 38.41O
ATOM13124OHOHM107 -4.356-16.858 33.433 1.0024.72O
ATOM13125OHOHM108 -25.427-29.192 -0.166 1.0062.91O
ATOM13126OHOHM109 4.631 -32.545 -5.119 1.0026.22O
ATOM13127OHOHM HO 36.338 -6.979 0.533 1.00 34.54O
ATOM13128OHOHM 111 23.881 31.874-30.013 1.0029.21O
ATOM13129OHOHM 112-13.157 7.871 -1.044 1.00 37.88O
ATOM13130OHOHM113 -9.502-31.899 40.681 1.0026.40O
ATOM13131OHOHM114-24.053 -27.881 -6.853 1.00 35.84O
ATOM13132OHOHM115-10.074-43.372 -4.811 1.0040.93O
ATOM13133OHOHM116-32.644 32.902-19.031 1.0017.63O
ATOM13134OHOHM117 17.207 -4.536 24.143 1.00 34.71O
ATOM13135OHOHM118 15.283 -40.099 5.656 1.00 27.60O
ATOM13136OHOHM119-34.180 36.049-17.168 1.0031.50O
ATOM13137OHOHM120 9.796 33.363 -38.429 1.0039.18O
ATOM13138OHOHM121 12.608 -49.722 -5.853 1.0027.35O
ATOM13139OHOHM122 37.702 1.810 13.418 1.00 30.86O
ATOM13140OHOHM123 -5.931 29.067 -30.053 1.00 34.57O
ATOM13141OHOH M124 23.571 -31.909-17.327 1.00 38.24O
ATOM13142OHOHM125 26.394 15.843 -1.606 1.00 32.56O
ATOM13143OHOH M126 13.518-32.912 15.710 1.0023.37O
[0540]ATOM13144OHOHM127 11.275 9.712 34.512 1.0055.46OATOM13145OHOHM 128 19.235-16.113 29.057 1.00 34.75O
ATOM13146OHOHM129 28.777 34.521 -20.831 1.0029.07O
ATOM13147OHOHM130 -34.401 21.670-16.128 1.0035.05O
ATOM13148OHOHM131 1.389 20.452 -1.581 1.0040.94O
ATOM13149OHOHM132-15.324 35.807 -0.461 1.0021.23O
ATOM13150OHOHM133-16.708 46.931 -20.901 1.0028.00O
ATOM13151OHOHM 134 -4.632 15.189 7.996 1.00 25.63O
ATOM13152OHOHM 135 25.008 -42.397-15.753 1.00 52.74O
ATOM13153OHOHM136 -6.612-12.117 1.592 1.0040.23O
ATOM13154OHOHM137 17.901 -12.716 22.239 1.00 35.21O
ATOM13155OHOHM 138 2.369 15.938-30.135 1.0031.69O
ATOM13156OHOHM139 -24.304 14.588 -0.642 1.0031.62O
ATOM13157OHOHM140 0.140 -1.311 14.362 1.00 48.00O
ATOM13158OHOHM 141 -8.314 11.595 12.034 1.0027.05O
ATOM13159OHOHM142-28.373-15.288 -8.235 1.00 39.77O
ATOM13160OHOHM 143 2.073 -35.489 41.483 1.0019.34O
ATOM13161OHOHM144-12.989 49.991 -15.134 1.0043.51O
ATOM13162OHOHM145 18.708 -28.889 -8.217 1.0036.95O
ATOM13163OHOHM 146 2.099 28.442-11.369 1.0042.83O
ATOM13164OHOHM147-14.326 17.419-21.335 1.00 33.86O
ATOM13165OHOHM148-13.454 31.345 17.794 1.00 30.55O
ATOM13166OHOHM 149 -27.295 44.411 3.169 1.0040.36O
ATOM13167OHOHM 150 3.939-16.495 31.742 1.00 35.69O
ATOM13168OHOHM 151 -2.294-24.869 18.423 1.0025.67O
ATOM13169OHOHM153-14.430-16.423 33.843 1.0022.95O
ATOM13170OHOH M 154 -27.169 -17.896 -10.130 1.00 34.04O
ATOM13171OHOHM155 16.719-40.426 1.744 1.0019.70O
ATOM13172OHOHM156-19.066 51.118-15.755 1.00 32.16O
ATOM13173OHOHM 157-11.185 -6.588 11.687 1.0021.09O
ATOM13174OHOHM158 31.903 35.620 -5.772 1.0045.73O
ATOM13175OHOHM159-10.987 7.381 15.855 1.0029.33O
ATOM13176OHOHM 160 0.160-36.965 25.070 1.0034.72O
ATOM13177OHOHM161 -8.262 39.975 -12.501 1.0042.90O
ATOM13178OHOHM162-10.990 4.714 38.482 1.00 53.33O
ATOM13179OHOHM 163-16.423-12.182 34.631 1.00 28.91O
ATOM13180OHOHM164 4.116-36.505 18.300 1.0028.59O
ATOM13181OHOHM165 30.701 11.903-36.536 1.0044.96O
ATOM13182OHOHM166 5.664 42.903 7.518 1.00 48.03O
ATOM13183OHOHM167 -5.450-24.201 22.063 1.0025.64O
ATOM13184OHOHM 168 0.929-35.336 46.647 1.0021.88O
ATOM13185OHOHM169 -30.922 -3.353 -3.331 1.00 37.40O
ATOM13186OHOHM 170 35.319 -1.024-10.819 1.0039.42O
ATOM13187OHOHM171 11.844 23.466-14.144 1.00 32.56O
[0541]ATOM13188OHOHM172 10.365 -6.676-15.976 1.0055.88OATOM 13189OHOHM173 -3.165 -30.802 23.005 1.0023.33O
ATOM13190OHOHM174 13.206 9.170-24.601 1.0036.98O
ATOM13191OHOHM175 24.747-21.105 0.991 1.0033.01O
ATOM13192OHOHM176-19.466 29.802 -27.739 1.0049.30O
ATOM13193OHOHM 177-21.326 23.802 19.937 1.0031.59O
ATOM13194OHOH M178 -0.376 35.767 1.993 1.00 29.90O
ATOM13195OHOHM179 5.208 -23.235 17.045 1.0043.78O
ATOM13196OHOHM180-12.616 5.782 14.848 1.00 39.05O
ATOM13197OHOHM181 7.189-41.518 33.298 1.0037.42O
ATOM13198OHOH M182 -3.991 33.895-12.740 1.0027.49O
ATOM13199OHOHM183 -11.858 -21.143 -17.346 1.00 50.09O
ATOM13200OHOHM 184-25.570 19.832 -8.777 1.00 36.85O
ATOM13201OHOH M185 -14.894 -27.443 -22.405 1.0051.87O
ATOM13202OHOHM186 -12.725 -30.892 26.404 1.00 34.30O
ATOM13203OHOHM187 35.920 8.428 26.392 1.0040.38O
ATOM13204OHOIIM188 0.230-28.651 7.273 1.00 39.88O
ATOM13205OHOH M189 34.705 -1.778 17.616 1.0028.78O
ATOM13206OHOH M190 16.004 31.084-16.307 1.0026.90O
ATOM13207OHOHM191 19.441 18.999 -43.563 1.0030.31O
ATOM13208OHOH M192-26.006-22.545 14.515 1.0043.20O
ATOM13209OHOH M193 19.017-34.276 19.681 1.00 35.14O
ATOM13210OHOHM194 -5.269 35.917-14.308 1.0015.12O
ATOM13211OHOHM195 8.612-16.634 19.714 1.00 28.82O
ATOM13212OHOH M196 12.030-38.382 22.118 1.0040.98O
ATOM13213OHOH M197 -8.139 -25.410 21.852 1.00 30.74O
ATOM13214OHOHM198 4.408 -17.508 -30.332 1.00 44.59O
ATOM13215OHOHM199 -7.681 34.143 -1.585 1.0025.98O
ATOM13216OHOH M 200 22.827 30.353 -31.947 1.0028.75O
ATOM13217OHOH M 201 19.157 3.872 5.863 1.00 29.51O
ATOM13218OHOH M 202 -4.546-36.653 42.658 1.0026.52O
ATOM13219OHOH M 203 -5.188 18.908-19.179 1.0042.79O
ATOM13220OHOH M 204 35.517 29.922 17.198 1.0049.52O
ATOM13221OHOH M 205 28.322 34.608 -25.017 1.0024.84O
ATOM13222OHOH M 206 24.361 37.648 -4.360 1.00 40.87O
ATOM13223OHOH M 207 -35.999 7.837 -7.307 1.0031.89O
ATOM13224OHOH M 208 -4.475 -28.948 -6.469 1.0048.89O
ATOM13225OHOH M 209 8.360 31.068 0.914 1.00 50.93O
ATOM13226OHOHM 210 -1.091 -8.311 17.416 1.0026.38O
ATOM13227OHOH M 211 2.838 34.495 14.678 1.00 35.37O
ATOM13228OHOH M 212 -4.636 -6.757 11.662 1.0027.71O
ATOM13229OHOH M 213 -3.773 -29.914 18.492 1.0018.07O
ATOM13230OHOH M 214 -2.471 -47.419-12.556 1.0033.13O
ATOM13231OHOHM 215-36.906 -7.219 -24.880 1.0033.20O
[0542]ATOM13232OHOH M 216 -7.933 -23.687 29.135 1.00 20.04OATOM13233OHOH M 217 1.346-11.828 21.183 1.00 33.20O
ATOM13234OHOH M 218 20.961 22.134 10.918 1.00 38.23O
ATOM13235OHOH M 219 10.375 16. 070 22.777 1.00 42.63O
ATOM13236OHOH M 220 18.464-32.434-12.485 1.00 36.90O
ATOM13237OHOH M 221 15.301-19.170-23.211 1.00 55.98O
ATOM13238OHOH M 222-16.643 4.282-12.167 1.0031.83O
ATOM13239OHOH M 223 -20.689 15.494 15.420 1.0024.07O
ATOM13240OHOH M 224 -27.890 5.622-11.859 1.00 35.72O
ATOM13241OHOH M 225 -11.297 -16.243 -33.136 1.00 29.79O
ATOM13242OHOH M 226 -12.147 -26.688 24.071 1.00 37.52O
ATOM13243OHOH M 227-19.499 34.440 9.257 1.00 30.99O
ATOM13244OHOH M 228 -20.798 37.357 12.134 1.0042.79O
ATOM13245OHOH M 229 18.363 -34.595 14.839 1.0027.71O
ATOM13246OHOH M 230 -0.607-30.444 -8.285 1.0029.06O
ATOM13247OHOHM 231-15.501 -21.548 23.163 1.00 34.93O
ATOM13248OHOH M 232 20.061 -26.806 0.948 1.00 27.11O
ATOM13249OHOH M 233 19.103 34.406-34.461 1.00 32.26O
ATOM13250OHOH M 234 4.294 -34.097 41.950 1.0020.18O
ATOM13251OHOH M 235 2.658 26.593 -30.373 1.0027.33O
ATOM13252OHOH M 236-18.009 53.105-14.789 1.00 43.56O
ATOM13253OHOH M 237 -1.537 -22.989 43.534 1.00 30.96O
ATOM13254OHOH M 238 -3.693 -35.763 29.365 1.00 39.10O
ATOM13255OHOH M 239 -1.310-38.915 49.490 1.00 32.42O
ATOM13256OHOH M 240 -4.342-21.359-15.281 1.0044.54O
ATOM13257OHOHM 241 -3.636 38.565 6.922 1.0027.22O
ATOM13258OHOH M 242 -8.356-31.060 28.952 1.00 30.87O
ATOM13259OHOHM 243-28.158 40.874-30.175 1.0034.17O
ATOM13260OHOH M 244-12.264 46.576 -3.057 1.00 39.83O
ATOM13261OHOH M 245 -9.670-29.363 5.936 1.0043.77O
ATOM13262OHOH M 246 32.107 -4.696 23.454 1.0032.57O
ATOM13263OHOH M 247 28.535 28.560 -27.332 1.00 39.85O
ATOM13264OHOH M 248 33.634 -9.817 17.706 1.0049.76O
ATOM13265OHOH M 249 21.225 -8.066 22.968 1.0045.61O
ATOM13266OHOH M 250 -8.944-12.960 -33.925 1.00 36.74O
ATOM13267OHOH M 251 -2.274-24.084 -27.602 1.0063.84O
ATOM13268OHOH M 252 -22.299 -23.624 -7.943 1.0043.86O
ATOM13269OHOH M 253 21.912-38.002-20.584 1.00 55.49O
ATOM13270OHOH M 254 36.941 33.925 1.562 1.00 36.31O
ATOM13271OHOH M 255 10.703 -39.729 44.458 1.0041.59O
ATOM13272OHOH M 256 -4.094-16.457 5.396 1.0043.36O
ATOM13273OHOHM 257-18.366-15.470 5.338 1.0038.31O
ATOM13274OHOHM 258 -13.959 -27.769 22.255 1.0036.48O
ATOM13275OHOH M 259 -7.096-18.867 -30.737 1.00 52.25O
[0543]ATOM13276OHOH M 260 -26.165 47.520 -24.572 1.00 36.28OATOM13277OHOH M 261 17.138-40.547 29.668 1.0045.24 O
ATOM13278OHOH M 262 13.614 18.862 26.977 1.00 44.80 O
ATOM13279OHOH M 263 23.108 0.262 -24.746 1.0043.22 O
ATOM13280OHOH M 264 4.533 13.122 1.837 1.00 70.79 O
ATOM13281OHOH M 265 22.415 41.692-19.135 1.0047.75 O
ATOM13282OHOHM 266-17.838 15.071 -11.991 1.0051.49O
ATOM13283OHOHM 267 -19.659 -12.446 5.410 1.0046.70O·ATOM13284OHOH M 268 5.836 -1.553 -32.151 1.00 54.67O
ATOM13285OHOH M 269 38.822 8.397 27.561 1.00 50.95 O
ATOM13286OHOH M 270-17.278 52.311 -11.693 1.0044.41O
ATOM13287OHOHM 271 28.418-13.776-11.621 1.00 50.59O
ATOM13288OHOH M 272-11.154 13.909 -2.560 1.00 24.82O
ATOM13289OHOHM 273-28.157 49.174 -5.068 1.0025.32O
ATOM13290OHOH M 274-22.432 45.686 -1.871 1.00 35.18〇
ATOM13291OHOH M 275 -30.255 22.863 -22.893 1.00 58.13O
ATOM13292OHOH M 276-20.927 -3.182 27.106 1.00 32.56O
ATOM13293OHOHM 277 -10.632 -34.495 31.549 1.0042.07O
ATOM13294OHOH M 278 38.562 28.809 16.343 1.00 39.80 O
ATOM13295OHOH M 279-26.205 25.924 1.415 1.00 35.17 O
ATOM13296OHOH M 280 27.807-29.304 5.666 1.0046.01 O
ATOM13297OHOH M 281 23.984-13.770 15.739 1.00 32.57 O
ATOM13298OHOH M 282 0.436 -26.306 22.603 1.0015.35 O
ATOM13299OHOH M 283 -1.116-12.714 23.824 1.0025.06O
ATOM13300OHOH M 284 6.347 22.473 10.415 1.0034.68 O
ATOM13301OHOHM 285 -28.648 -16.664 23.074 1.0039.65O
ATOM13302OHOH M 286 16.744 14.251 -41.450 1.00 33.35 O
ATOM13303OHOH M 287 -2.147-28.149 15.108 1.0031.76O
ATOM13304OHOH M 288-16.062 5.669 22.260 1.0028.03 O
ATOM13305OHOH M 289 -4.397 10.734-11.735 1.0041.49O
ATOM13306OHOH M 290 20.018 29.932 -10.520 1.00 36.39 O
ATOM13307OHOHM 291 16.419-34.669 40.896 1.00 37.31 O
ATOM13308OHOH M 292 4.815 -2.598 25.117 1.00 32.37 O
ATOM13309OHOH M 293 13.962-36.179 49.667 1.0026.80 O
ATOM13310OHOH M 294 2.561 -13.255 48.125 1.0043.86 O
ATOM13311OHOHM295-12.178 7.775 3.706 1.00 30.97O
ATOM13312OHOH M 296 17.880 23.234 1.340 1.0037.03 O
ATOM13313OHOH M 297 32.839-13.055 4.802 1.00 45.34 O
ATOM13314OHOH M 298 18.225-14.352 43.750 1.0049.85 O
ATOM13315OHOH M 299 15.156 7.420 -32.788 1.00 39.55 O
ATOM13316OHOH M 300 4.120 25.608 -3.863 1.00 36.96 O
ATOM13317OHOH M 301 -38.368 -7.399-10.566 1.0041.62O
ATOM13318OHOHM 302 21.921 -20.810 27.201 1.00 35.46 O
ATOM13319OHOH M 303 26.990-33.001 7.939 1.00 33.28 O
[0544]ATOM13320OHOH M 304 6.189-17.486 29.098 1.0025.64OATOM13321OHOH M 305 14.870 3.265 34.194 1.0045.71O
ATOM13322OHOH M 306 22.270 13.916 13.616 1.0035.74O
ATOM13323O HOH M 307 21.615 39.699-29.384 1.0044.02O
ATOM13324OHOHM 308-32.653 31.121 -29.066 1.0035.34O
ATOM13325OHOH M 309 -1.428 13.428 9.970 1.0042.25O
ATOM13326OHOHM 310-37.749 33.574 -2.670 1.0044.50O
ATOM13327OHOHM 311 4.080 28.979 5.794 1.00 32.28O
ATOM13328OHOHM 312-35.311 33.027-19.588 1.00 37.18O
ATOM13329OHOHM 313-18.808 -3.112 28.733 1.0043.33O
ATOM13330OHOH M 314 29.978-10.358 14.623 1.00 30.80O
ATOM13331OHOHM 315 -25.081 -13.788 -37.448 1.0045.37O
ATOM13332OHOH M 316 -20.051 -11.038 -36.806 1.00 53.44O
ATOM13333OHOH M 317-10.353 -25.190 44.251 1.00 35.92O
ATOM13334OHOHM318 16.810 14.824-32.683 1.00 32.61O
ATOM13335OHOHM 319 -2.999 -38.547 12.153 1.0027.18O
ATOM13336OHOH M 320 -25.116 8.516-14.436 1.00 38.03O
ATOM13337OHOHM 321 -5.505-16.117-16.848 1.00 35.93O
ATOM13338OHOH M 322 -25.664 49.549 -22.495 1.0027.59O
ATOM13339OHOH M 323 6.673 -50.143 3.803 1.0033.59O
ATOM13340OHOH M 324 23.158 7.056 5.402 1.00 25.16O
ATOM13341OHOH M 325 12.683 -40.778 5.932 1.0033.50O
ATOM13342OHOH M 326 18.279 2.511 -3.492 1.00 30.81O
ATOM13343OHOH M 327 34.240 22.385 2.488 1.00 36.49O
ATOM13344OHOH M 328 25.483 -9.033 -21.812 1.0066.62O
ATOM13345OHOH M 329 -6.506 30.049 -25.354 1.0028.19O
ATOM13346OHOH M 330 -29.282 50.317-10.865 1.0027.88O
ATOM13347OHOH M 331 25.359 9.207 14.433 1.00 35.29O
ATOM13348OHOH M 332-19.854 16.345 -4.676 1.0030.02O
ATOM13349OHOH M 333 4.663 12.399 28.163 1.00 41.34O
ATOM13350OHOH M 334 21.265 5.297 11.516 1.0025.12O
ATOM13351OHOHM335-13.161 42.979 -20.251 1.0027.47O
ATOM13352OHOH M 336-30.455 39.370 -3.915 1.00 36.86O
ATOM13353OHOH M 337 20.656 -31.127 24.858 1.00 31.31O
ATOM13354OHOH M 338 18.646 -34.082 44.149 1.0046.72O
ATOM13355OHOH M 339 10.433 -33.933 -8.230 1.0024.20O
ATOM13356OHOH M 340 24.210 -5.604 1.709 1.00 31.98O
ATOM13357OHOH M 341-17.693 24.796 -9.113 1.0021.88O
ATOM13358OHOH M 342-31.999 40.837 -5.087 1.0023.84O
ATOM13359OHOH M 343 -19.101 22.126 19.035 1.0034.06O
ATOM13360OHOH M 344 -16.542 -29.481 36.520 1.00 34.60O
ATOM13361OHOH M 345 -4.627 32.940-10.429 1.0043.83O
ATOM13362OHOH M 346-28.136 10.376-20.267 1.00 38.49O
ATOM13363OHOHM 347-21.749 52.463 -5.452 1.0028.28O
[0545]ATOM13364OHOH M 348 40.746 7.082 5.608 1.0041.72OATOM13365OHOH M 349-19.464 4.895 23.980 1.0032.90O
ATOM13366OHOH M 350 -3.051 -9.350-16.049 1.0033.06O
ATOM13367OHOHM351 2.745 -10.283 47.106 1.00 38.32O
ATOM13368OHOH M 352 25.352 7.896 16.677 1.0021.23O
ATOM13369OHOH M 353 8.093 -47.322-10.537 1.00 34.59O
ATOM13370OHOH M 354-10.797 32.295 -9.464 1.0023.52O ATOM13371OHOH M 355-12.986-35.110 -2.411 1.0043.98O
ATOM13372OHOH M 356-17.553-16.847 36.190 1.0031.73O
ATOM13373OHOH M 357 -1.550 43.973 16.763 1.00 50.36O
ATOM13374OHOH M 358 23.498 20.062 -40.865 1.00 40,48O
ATOM13375OHOH M 359 22.828 14.680 -33.199 1.00 45.75O
ATOM13376OHOH M 360 -25.904 36.483 -30.350 1.00 35.33O
ATOM13377OHOHM 361 -16.561 -21.822 10.088 1.00 41.38O
ATOM13378OHOH M 362 -2.803 -37.098 35.972 1.00 29.37O
ATOM13379OHOHM 363 -1.052 4.698 -26.398 1.0046.36O
ATOM13380OHOH M 364 3.355 1.628 8.061 1.0045.07O
ATOM13381OHOH M 365 -23.413 21.984 -25.989 1.00 32.83O
ATOM13382OHOH M 366 -7.696 6.791 -1.200 1.0044.84O
ATOM13383OHOH M 367 9.622 7.338 13.062 1.00 32.33O
ATOM13384OHOH M 368-14.230-27.653 16.319 1.00 30.33O
ATOM13385OHOH M 369 -4.007 -34.905 -2.158 1.00 37.36O
ATOM13386OHOH M 370 8.301 -21.206-11.943 1.00 36.42O
ATOM13387OHOH M 371 -39.331 -24.021 -24.078 1.00 46.13O
ATOM13388OHOH M 372 -6.594-17.439 7.896 1.0051.13O
ATOM13389OHOH M 373 18.988-17.502 26.657 1.0031.43O
ATOM13390OIIOHM 374 -0.210-14.164 14.666 1.0045.45O
ATOM13391OHOH M 375 11.407 13.803 -31.464 1.00 44.09O
ATOM13392OHOHM 376 0.275 36.103 -4.465 1.0041.06O
ATOM13393OHOH M 377 -36.144 24.173-13.260 1.00 36.40O
ATOM13394OHOH M 378 -7.041 -2.357-23.362 1.00 34.92O
ATOM13395OHOH M 379 23.347 42.133 -13.121 1.0042.64O
ATOM13396OHOHM 380 34.528 8.588-19.374 1.0045.96O
ATOM13397OHOHM 381-31.338 27.129 -23.070 1.00 34.49O
ATOM13398OHOHM 382 -29.835 24.419-29.158 1.00 50.24O
ATOM13399OHOHM 383 8.993 34.637 4.403 1.0044.64O
ATOM13400OHOH M 384 27.288 15.028 23.100 1.00 37.27O
ATOM13401OHOH M 3 85 -29.681 -28.349 2.822 1.0049.59O
ATOM13402OHOHM 386 -2.803 0.545 14.427 1.0055.15O
ATOM13403OHOH M 387 14.244-14.956 42.725 1.0046.85O
ATOM13404OHOHM 388-21.842 48.113 -1.177 1.00 30.83O
ATOM13405OHOHM 389 14.814-23.816 41.020 1.0025.98O
ATOM13406OHOHM 390-18.439 -6.203-15.449 1.0028.34O
ATOM13407OHOH M 391 9.800 -47.096 3.051 1.00 32.98O
[0546]ATOM13408OHOH M 392 7.889-19.584 15.396 1.00 26.42OATOM13409 OHOH M 393 4.045 -8.178 24.081 1.0026.05O
ATOM13410OHOH M 394 5.129-31.826-11.174 1.0025.03O
ATOM13411OHOH M 395 23.339 16.566-10.079 1.00 33.18O
ATOM13412OHOH M 396 -29.092 3.540 -28.161 1.00 32.01O
ATOM13413OHOH M 397 -24.235 -20.854 -7.482 1.0043.52O
ATOM13414OHOH M 398 -10.236 -29.087 -13.722 1.00 20.58O
ATOM13415OHOH M 399 -0.231 -38.959 44.632 1.00 33.97O·ATOM13416OHOH M 400-13.391 27.658 -4.491 1.0021.60O
ATOM13417OHOH M 401 6.703 -33.490 -9.036 1.0040.23O
ATOM13418OHOH M 402 -34.363 -31.850 -22.853 1.00 39.76O
ATOM13419OHOH M 403 -36.006 -0.762 -8.673 1.00 38.58O
ATOM13420OHOH M 404 -9.658 15.181-30.821 1.0029.68O
ATOM13421OHOH M 405 17.979 21.914-14.217 1.00 37.16O
ATOM13422OHOH M 406 0.886 -7.952 15.885 1.0029.86O
ATOM13423OHOH M 407 -21.486 24.316-28.588 1.0040.18O
ATOM13424OHOH M 408-10.655 8.882 20.579 1.0031.09O
ATOM13425OHOH M 409 -9.272 42.279-14.038 1.0042.23O
ATOM13426OHOH M 410-15.943-24.689 9.422 1.00 38.16O
ATOM13427OHOH M 411 30.328 19.356 -7.080 1.00 39.63O
ATOM13428OHOH M 412 -20.625 -11.293 -39.858 1.00 49.98O
ATOM13429OHOH M 413 -7.605 11.356-28.403 1.0031.76O
ATOM13430OHOH M 414 3.463-21.085-11.961 1.0052.99O
ATOM13431OHOH M 415 -0.920 40.374 -4.627 1.00 48.52O
ATOM13432OHOH M 416 21.509-19.766 21.686 1.0045.33O
ATOM13433OHOH M 417 26.007 21.105 23.832 1.00 50.21O
ATOM13434OHOH M 418 23.992-30.675 5.115 1.00 34.10O
ATOM13435OHOH M 419 26.515-17.879 4.748 1.00 30.06O
ATOM13436OHOH M 420-30.848 1.781 -29.555 1.0031.01O
ATOM13437OHOH M 421 -2.121 -10.920 35.156 1.0045.50O
ATOM13438OHOH M 422 28.822 43.188 0.805 1.0048.91O
ATOM13439OHOH M 423 31.632 31.366-17.749 1.00 56.89O
ATOM13440OHOH M 424 12.509-45.841 -18.522 1.00 39.54O
ATOM13441OHOH M 425 39.190 11.073 29.145 1.00 46.78O
ATOM13442OHOH M 426 -15.724 -25.042 -24.809 1.00 35.19O
ATOM13443OHOH M 427 -3.459 23.668 -3.695 1.00 36.17O
ATOM13444OHOH M 428 11.143 30.751 1.065 1.0043.30O
ATOM13445OHOH M 429 20.475 18.000 6.144 1.0043.54O
ATOM13446OHOH M 430 -9.017-23.525 16.022 1.0028.22O
ATOM13447OHOH M 431 36.177 5.022 -6.098 1.0049.43O
ATOM13448OHOH M 432 12.409 -21.463 10.721 1.0046.96O
ATOM13449OHOH M 433 29.105 36.037-10.391 1.00 50.72O
ATOM13450OHOH M 434 18.830-12.625 -6.947 1.00 42.95O
ATOM13451OHOHM 435-16.700 22.658 20.214 1.0029.24O
[0547]ATOM13452OHOH M 436-18.132 29.129 -8.085 1.00 30.93OATOM13453OHOH M 437 32.115 1.696-17.913 1.00 35.82O
ATOM13454OHOH M 438 15.979 29.553 -12.373 1.0041.74O
ATOM13455OHOH M 439 13.959 24.981 -12.749 1.00 24.27O
AlOM13456OHOH M 440-12.913 22.257 26.877 1.00 32.73O
ATOM13457OHOH M 441-25.401 8.770 -22.636 1.0040.79O
ATOM13458OHOH M 442 33.985 22.535 -7.073 1.0040.10 O
ATOM13459OHOHM 443 3.076 8.867 20.769 1.0038.92 O·ATOM13460OHOH M 444 -5.378 38.169-15.611 1.00 39.27O
ATOM13461OHOH M 445 -9.847 -23.952 46.764 1.0041.65O
ATOM13462OHOH M 446 15.815 38.915 11.109 1.00 54.64 O
ATOM13463OHOH M 447 -1.040 6.906-25.006 1.00 53.36O
ATOM13464OHOH M 448 -24.874 -23.575 -5.879 1.0062.38O
ATOM13465OHOH M 449-12.794 -5.358 7.891 1.0043.27O
ATOM13466OHOH M 450 14.007 -22.336 -1.910 1.00 34.15O
ATOM13467OHOH M 451 -1.214-16.342-33.546 1.0051.90O
ATOM13468OHOH M 452 -7.112 29.869 -7.509 1.0026.49O
ATOM13469OHOH M 453 -7.656-40.488-20.700 1.0031.03O
ATOM13470OHOH M 454 21.552 -35.287 25.812 1.00 55.53O
ATOM13471OHOH M 455 10.280 21.483-11.969 1.00 54.25O
ATOM13472OHOH M 456 -1.045 -29.189-23.668 1.00 35.88O
ATOM13473OHOH M 457 27.831 -23.865 40.054 1.00 66.39O
ATOM13474OHOH M 458-28.607 42.039 -24.887 1.00 30.81O
ATOM13475OHOH M 459 -8.425 50.666-15.558 1.00 36.24O
ATOM13476OHOH M 460 13.057-17.226 20.410 1.0042.16O
ATOM13477OHOH M 461 -13.597 6.468 11.215 1.0030.11O
ATOM13478OHOH M 462-30.466 1.116 4.571 1.00 37.15O
ATOM13479OHOH M 463-17.259 16.772 -6.357 1.00 35.44O
ATOM13480OHOH M 464 -1.706-19.361 41.485 1.00 28.18O
ATOM13481OHOH M 465 12.738 7.922 30.967 1.0042.39 O
ATOM13482OIIOIIM 466-21.100 11.579-18.807 1.00 36.86O
ATOM13483OHOH M 467-21.158 0.407 26.052 1.00 40.82O
ATOM13484OHOH M 468 -8.917 14.242 14.940 1.0026.72 O
ATOM13485OHOH M 469 4.454 -25.955 16.274 1.00 33.39O
ATOM13486OHOH M 470 13.716-31.700 51.713 1.00 33.59O
ATOM13487OHOH M 471 -28.030 49.145 -22.613 1.0034.52O
ATOM13488OHOH M 472 -5.327 -37.085 -8.885 1.0031.37O
ATOM13489OHOH M 473 -6.004 3.221 35.029 1.0043.23 O
ATOM13490OHOH M 474 -9.568 -42.507 -17.242 1.00 35.06O
ATOM13491OHOH M 475 -28.158 48.692 -12.523 1.0039.19O
ATOM13492OHOH M 476 2.772 -38.737 40.031 1.0041.07O
ATOM13493OHOH M 477 26.650 -39.604 -10.753 1.0032.81O
ATOM13494OHOH M 478 -4.281 15.525 -2.353 1.00 48.24O
ATOM13495OHOH M 479 4.522 40.607 10.014 1.0051.17 O
[0548]ATOM13496OHOH M 480 24.381 -34.898 -7.627 1.0042.71OATOM13497OHOH M 481 -8.016 28.943 -27.365 1.0026.89O
ATOM13498OHOH M 482 -3.401 30.251 -0.999 1.0025.41O
ATOM13499OHOH M 483 -14.696 -34.007 35.701 1.0045.28O
ATOM13500OHOH M 484 10.080 31.155 -39.497 1.00 25.56O
ATOM13501OHOH M 485 18.704-33.201 40.928 1.00 30.81O
ATOM13502OHOH M 486 -0.243 -24.262 45.698 1.00 30.24O
ATOM13503OHOH M 487-14.198 41.547 16.222 1.00 43.84O·ATOM13504OHOH M 488-24.128 55.841 -3.147 1.00 34.77O
ATOM13505OHOH M 489-23.137 16.224-10.020 1.0042.19O
ATOM13506OHOH M 490 5.484 -12.469 49.817 1.0047.43O
ATOM13507OHOH M 491 3.580 -40.467 30.353 1.0031.03O
ATOM13508OHOH M 492-30.625 24.461 16.481 1.0047.86O
ATOM13509OHOH M 493 3.608 17.096-35.106 1.0041.76O
ATOM13510OHOH M 494-29.914 40.085 -26.431 1.0031.90O
ATOM13511OHOH M 495 10.690 -20.478 4.212 1.00 44.49O
ATOM13512OHOH M 496 22.499-14.726 -4.147 1.00 33.78O
ATOM13513OHOH M 497-24.969 15.529 15.088 1.00 38.58O
ATOM13514OHOH M 498 -21.766 33.171 14.681 1.0042.64O
ATOM13515OHOH M 499 17.116 26.213 -4.424 1.0043.31O
ATOM13516OHOH M 500-18.290 9.298 15.788 1.0026.37O
ATOM13517OHOH M 501 17.862 5.172 -5.184 1.00 27.73O
ATOM13518OHOH M 502 -26.495 7.296 1.764 1.00 33.22O
ATOM13519OHOH M 503 -20.806-12.051-18.015 1.0040.96O
ATOM13520OHOH M 504 3.525 -12.782 19.181 1.0039.18O
ATOM13521OHOH M 505 34.485 15.286 2.111 1.0031.43O
ATOM13522OHOH M 506 16.344 -45.444-15.875 1.0031.85O
ATOM13523OHOH M 507 2.263 17.868 -32.515 1.0041.25O
ATOM13524OHOH M 508 33.180 30.622 -12.865 1.00 35.88O
ATOM13525OHOH M 509 -6.156 8.523 -30.799 1.0042.86O
ATOM13526OHOHM 510 3.949 4.775 27.220 1.0047.25O
ATOM13527OHOHM 511-10.301 6.016 3.094 1.00 57.97O
ATOM13528OHOH M 512 -2.025 -16.335 24.013 1.00 28.77O
ATOM13529OHOHM 513-38.993 33.931 -19.398 1.0042.90O
ATOM13530OHOH M 514 4.598 46.817-21.786 1.0040.06O
ATOM13531OHOHM 515 35.411 30.903 -4.829 1.0042.65O
ATOM13532OHOHM 516 7.146-23.869 3.578 1.00 36.40O
ATOM13533OHOH M 517-20.473 52.889-18.292 1.0051.35O
ATOM13534OHOHM 518-41.025 -21.021 -30.544 1.00 50.23O
ATOM13535OHOHM 519 -7.842 7.223 -20.782 1.0045.88O
ATOM13536OHOH M 520 15.643 -41.317 46.631 1.00 59.01O
ATOM13537OHOH M 521 -1.781 7.420 -29.675 1.0041.78O
ATOM13538OHOH M 522 27.325 -25.976 37.587 1.00 38.59O
ATOM13539OHOH M 523 8.277 6.079 11.629 1.00 44.35O
[0549]ATOM 13540OHOH M 524 13.350-47.497 4.486 1.00 50.91OATOM 13541OHOH M 525 10.163 33.506-35.624 LOO 34.51O
ATOM 13542OHOH M 526 28.109-26.975 4.139 1.0041.68O
ATOM 13543OHOH M 527-15.012-29.826 34.418 1.0041.85O
ATOM13544OHOH M 528 1.374 7.619-24.608 1.00 50.37O
ATOM13545OHOH M 529 0.976 25.321 16.191 LOO 39.40O
ATOM13546OHOH M 530 32.856 11.641 -21.493 1.00 36.59O ATOM13547OHOHM531 21.866 24.321 7.724 1.0040.20O
ATOM13548OHOH M 532 13.611 -37.652-28.607 1.00 50.82O
ATOM13549OHOH M 533 4.602 -30.353 -26.808 1.00 46.44O
ATOM13550OHOH M 534 -22.080 1.592 3.272 1.00 48.15O
ATOM13551OHOH M 535 11.851 -28.861 -30.950 1.00 46.66O
ATOM13552OHOH M 536 -10.625 -21084 -13.790 1.0029.96O
ATOM13553OHOH M 537 37.855 15.165 27.089 1.0035.29O
ATOM13554OHOHM 538-13.746 22.108 -30.541 1.0043.97O
ATOM13555OHOH M 539 -9.603 -26.287 -10.270 1.00 32.37O
ATOM13556OHOH M 540 -24.517 -18.408 16.626 1.00 52.68O
ATOM13557OHOH M 541 -8.252-38.172 39.096 1.0032.94O
ATOM13558OHOH M 542-11.949 22.958-29.405 1.00 52.11O
ATOM13559OHOH M 543 28.054 24.821 18.971 1.0037.65O
ATOM13560OHOH M 545 23.210 9.878 32.640 1.0052.28O
ATOM13561OHOH M 546-15.557 15.666-14.561 1.00 52.40O
ATOM13562OHOH M 547 -18.996 -20.248 -25.762 1.00 58.19O
ATOM13563OHOH M 548 5.672 1.771 34.139 1.0044.86O
ATOM13564OHOH M 549 1.359 1.944 13.718 1.0045.70O
ATOM13565OHOH M 550 -25.466 -30.677 -5.119 1.00 45.00O
ATOM13566OHOH M 551 5.701 -23.252 13.462 1.00 39.08O
ATOM13567OHOH M 552 -5.619-28.700 20.825 1.0048.98O
ATOM13568OHOH M 553 20.561 -20.920 36.646 1.00 35.35O
ATOM13569OHOH M 554 -16.103 -11.587 -32.386 1.00 54.48O
ATOM13570OHOH M 555 -4.378 19,013 -3.316 1.00 56.69O
ATOM13571OHOH M 556 -0.046 16.844 -6.836 1.00 48.43O
ATOM13572OHOH M 557 -1.996 -6.622 33.219 1.0035.61O
ATOM13573OHOH M 558-18.572 19.122-25.413 1.00 38.26O
ATOM13574OHOH M 559 3.154 3.658 -23.995 1.0037.86O
ATOM13575OHOH M 560 4.670 -27.156 14.097 1.0043.69O
ATOM13576OHOH M 561-38.697 33.527-22.363 1.0042.41O
ATOM13577OHOH M 562 -28.514 -14.388 20.149 1.00 39.85O
ATOM13578OHOH M 563 -33.164-25.861 -11.667 1.0044.57O
ATOM13579OHOH M 564 22.421 -13.679 -7.184 1.0045.72O
ATOM13580OHOH M 565 40.169 23.863 22.030 1.0048.89O
ATOM13581OHOH M 566 -4.781 34.872 -8.323 1.0030.23O
ATOM13582OHOH M 567-32.908 16.288 3.321 1.0045.29O
ATOM13583OHOH M 568 -23.692 58.394 2.897 1.0043.13O[0550]ATOM13584OHOHM 569-22.435 51.742-19.983 1.0042.91O
ATOM13585OHOH M 570 38.231 30.717 3.925 1.00 53.39O
ATOM13586OHOHM 571 10.392 -2.724 4.013 1.0056.25O
ATOM13587OHOH M 572 -4.560 7.355-21.383 1.0064.99O
ATOM13588OHOHM 573 -29.076 -12.627 -0.820 1.00 53.14O
ATOM13589OHOH M 574 32.118 26.972 -24.887 1.0036.12O
ATOM13590OHOH M 575 -22.684 27.830 21.718 1.00 37.40O
ATOM13591OHOH M 576 26.302 9.337 10.399 1.0028.29O
ATOM13592OHOH M 577 11.225 -36.548 19.228 1.00 39.11O
ATOM13593OHOHM 578 14.106-39.427 1.687 1.0026.84O
ATOM13594OHOH M 579 20.191 -0.198 23.979 1.0045.65O
ATOM13595OHOH M 580 9.874-41.129 41.575 1.0043.25O
ATOM13596OHOHM 581-21.420 29.238 23.802 1.0042.60O
ATOM13597OHOH M 582 8.950 15.231 -29.389 1.00 35.73O
ATOM13598OHOHM 583-12.633 14.426-21.022 1.0042.33O
ATOM13599OHOHM 584 12.769-19.812-13.805 1.0051.50O
ATOM13600OHOH M 585 1.567 19.621 -6.354 1.00 48.07O
ATOM13601OHOHM 586 31.193 31.490-20.190 1.00 57.77O
ATOM13602OHOH M 587 18.299 0.936 6.720 1.00 55.43O
ATOM13603OHOH M 588 38.006 26.239 19.380 1.0044.49O
ATOM13604OHOH M 589 -1.576-29.651 17.057 1.00 36.21O
ATOM13605OHOH M 590 8.027 28.475 -30.408 1.0024.19O
ATOM13606OHOH M 591 12.061 30.786 -40.987 1.00 30.52O
ATOM13607OHOH M 592 28.051 31.075 -29.188 1.00 32.27O
ATOM13608OHOH M 593 -3.489-38.860 51.100 1.0029.94O
ATOM13609OHOH M 594 0.857-41.471 30.953 1.00 42.25O
ATOM13610OHOH M 595 -7.086-21.456-28.644 1.00 36.17O
ATOM13611OHOH M 596 -2.115 20.307 -4.694 1.00 38.92O
ATOM13612OHOH M 597 -6.526 13.439 12.840 1.00 36.66O
ATOM13613OHOHM598 12.255 -39.175 19.490 1.0035.15O
ATOM13614OHOH M 599 -8.034 40.497-16.879 1.00 31.62O
ATOM13615OHOH M 600 5.113-36.057 43.183 1.00 27.34O
ATOM13616OHOH M 601 -4.633 37.443-18.200 1.0018.43O
ATOM13617OHOH M 602-29.152 27.120 0.439 1.00 29.98O
ATOM13618OHOH M 603 -30.577 39.574 -1.177 1.0033.09O
ATOM13619OHOH M 604-21.556 31.391 12.956 1.0040.15O
ATOM13620OIIOH M 605 7.891 30.362-41.029 1.00 23.56O
ATOM13621OHOH M 606 27.273 -34.979 -9.149 1.0032.52O
ATOM13622OHOH M 607 1.069-10.457 23.983 1.0047.28O
ATOM13623OHOH M 608 -21.459 4.499 26.016 1.0041.44O
ATOM13624OHOH M 609 -4.622 4.376 36.892 1.0044.31O
ATOM13625OHOH M 610-11.206 16.473 -28.704 1.0042.81O
ATOM13626OIIOH M 611 -36.457 -29.040 -20.467 1.00 37.34O
ATOM13627OHOH M 612 10.405 7.100 9.084 1.0028.65O
[0551]ATOM 13628 O HOH M 613 -3.252 33.086 -6.701 1.00 36.36 O ATOM 13629 O HOH M 614 -3.914-21.870 44.370 1.0025.21 O ATOM 13630 O HOH M 615-26.149-13.214 -2.386 1.00 35.43 O ATOM 13631 O HOHM 616-14.100 16.709 -30.707 1.0043.32 O ATOM 13632 O HOHM 617-15.161 17.701 -26.013 1.0046.89 O ATOM 13633 O HOHM 618 35.704 15.576 -0.606 1.0045.26 O ATOM 13634 O HOH M 619-19.495 23.512-10.476 1.0023.09 O ATOM 13635 O HOH M 620 0.830 42.199 -6.104 1.0037.53 O ATOM 13636 O HOHM 621-24.172 14.195 16.747 1.00 37.35 O ATOM 13637 O HOHM 622-17.516-34.191 35.744 1.0045.95 O ATOM 13638 O HOH M 623 -6.296 -3.506 -20.655 1.00 35.68 O ATOM 13639 O HOH M 624-34.272 14.186 2.507 1.00 39.98 O ATOM 13640 O HOH M 625 -3.584 -3.695 -20.723 1.0051.05 O ATOM 13641 O HOH M 626 13.891 29.038 -14.019 1.0031.96 O ATOM 13642 O HOHM 627 6.778 -24.366 -0.286 1.00 33.35 O ATOM 13643 O HOH M 628 -3.603 40.085 -14.385 1.00 30.51 O ATOM 13644 O HOH M 629 -21.354 54.006 -20.629 1.0043.02 O ATOM 13645 O HOH M 630 7.783 -12.669 47.715 1.0041.94 O ATOM 13646 O HOH M 631 -32.806 41.776 -0.960 1.0043.24 O ATOM 13647 O HOH M 632 -3.130 19.092 -6.520 1.00 44.65 O ATOM 13648 O HOH M 633 28.075 30.321 -31.779 1.0048.84 O ATOM 13649 O HOH M 634 8.761 -44.098 40.392 1.0042.48 O ATOM 13650 O HOH M 635-15.035 14.269 -26.900 1.00 40.24 O ATOM 13651 O HOHM 636 7.009 -23.028 -2.471 1.0045.42 O ATOM 13652 O HOH M 637 9.448 -24.238 -4.160 1.0029.54 O ATOM 13653 O HOH M 638 10.287 25.493 -44.115 1.00 13.97 O ATOM 13654 O HOH M 639 10.215 16.174-26.531 1.00 26.51 O ATOM 13655 O HOH M 640 11.920 14.145 -27.301 1.00 33.06 O ATOM 13656 O HOH M 641 7.389 44.026-20.468 1.00 27.92 O TER END
[0552](实施例4)成花素的晶体的制备
[0553](I)表达载体的制备
[0554]对插入了编码序列编号I所示全长Hd3a (I〜179残基）中的6〜170残基的cDNA的质粒进行限制酶处理，使限制酶处理后的片段与编码GST的多核苷酸融合并导入到载体中，并且将该载体导入到大肠杆菌中。在大肠杆菌中表达GST融合Hd3a蛋白质。在对大肠杆菌进行了培养之后，对大肠杆菌进行离心并回收，从而从溶解溶液中提纯Hd3a蛋白质。之后，利用SDS-聚丙烯酰胺电泳法（SDS-PAGE)进行了分析，结果得知Hd3a蛋白质的纯度为95%以上。
[0555]利用含有20mM NaCl的IOmM Tris缓冲液（pH为7. 5)对提纯后的Hd3a蛋白质进行透析，并浓缩至浓度成为5mg/ml。晶化是I μ I将蛋白质溶液和I μ I沉淀剂溶液（O. IM卡可基酸（pH为6. 5)、0· 2M酒石酸铵、30% PEG8000)加以混合，并使用坐滴法在4°C下进行。在约I天后得到了 O. ImmXO. I画的单晶体。[0556]得到的晶体为以下2种。
[0557]〔成花素I〕晶体的空间群为P63,晶格常数为a=65.9A、b=65.9 A、c=59.8 A、α=90°、β = 90°、γ = 120°，分辨率为 1.3 A的晶体。
[0558]〔成花素2〕晶体的空间群为P6522，晶格常数为a=66.0A、b=66.0A、c=60.2 Α、α = 90°、β = 90°、Y = 120°，分辨率为 1.4A的晶体。
[0559](实施例5)关于成花素晶体的X射线结构分析
[0560]对于得到的结晶，在放射光科学研究设施Photon Factor的BL5A光束线中使用CCD检测器对其X射线衍射像进行了测量。根据得到的衍射像而得到了成花素的原子坐标。
[0561]收集X射线衍射数据，并进行了各个衍射斑点的指数标定和衍射强度的计算。利用分子置换法从得到的衍射强度和搜索模型确定了相位角。使用这些衍射斑点的衍射强度
和相位角，并通过傅里叶逆变换而导出了电子密度图。根据得到的电子密度图构建了原子坐标。
[0562]具体而言，使用HKL2000对得到的数据进行处理，并利用SCALEPACK进行了缩放。作为搜索模型，利用分子置换法确定了成花素的晶体结构。使用CNS和REFMAC以1.3 A和
1.4 A对得到的模型进行了精密化。在各精密化之后，使用COOT并根据作为电子密度图的
2Fo-Fc map对得到的模型进行了补正。
[0563]将从上述成花素I的晶体得到的原子坐标表示于后述的表2中。
[0564](表2)成花素的原子坐标
[0565]ATOM I N GLYA 5 8.706 4.683 11.752 1.00 46.29 N ATOM 2 CA GLYA 5 9.393 3.368 11.940 1.00 46.24 C ATOM 3 C GLYA 5 10.574 3.541 12.876 1.0046.01 C ATOM 4 O GLYA 5 10.375 3.941 14.027 1.0046.10 O ATOM 5 N ARGA 6 11.804 3.261 12.435 1.0045.65 N ATOM 6 CA ARGA 6 12.210 2.730 11.112 1.00 45.26 C ATOM 7 CB ARGA 6 11.465 3.383 9.940 1.00 45.27 C ATOM 8 CG ARGA 6 11.788 2.843 8.535 1.0045.56 C ATOM 9 CD ARGA 6 11.793 1.306 8.431 1.00 44.76 C ATOM 10 NE ARGA 6 10.455 0.711 8.470 1.0044.76 N ATOM 11 CZ ARGA 6 10.174 -0.544 8.112 1.0044.36 C ATOM 12 NHl ARGA 6 11.133 -1.355 7.673 1.0043.31 N ATOM 13 NH2ARGA 6 8.926 -0.989 8.181 1.00 42.93 N ATOM 14 C ARGA 6 13.715 2.991 11.021 1.0044.86 C ATOM 15 O ARGA 6 14.443 2.270 10.333 1.0044.69 O ATOM 16 N ALAA 7 14.138 4.063 11.699 1.0044.40 N ATOM 17 CA ALAA 7 15.500 4.266 12.224 1.0043.74 C ATOM 18 CB ALAA 7 15.950 3.064 13.070 1.0043.95 C ATOM 19 C ALAA 7 16.621 4.709 11.283 1.00 43.16 C ATOM 20 O ALAA 7 17.202 3.903 10.552 1.0043.44 O ATOM 21 N ARGA 8 16.913 6.009 11.342 1.0042.15 N ATOM 22 CA ARGA 8 18.164 6.599 10.848 1.00 40.76 C
[0566]ATOM23CB ARGA819.3755.87411.4721.00 40.84CATOM24CG ARGA820.3776.76912.2121.00 40.73C
ATOM25CD ARGA821.1577.70611.2921.0041.25C
ATOM26NE ARGA821.4847.09310.0031.0041.84N
ATOM27CZ ARGA822.6676.576 9.6821.0043.45C
ATOM28NHl ARGA822.8496.045 8.4781.0043.18N
ATOM29NH2ARGA823.6716.58210.5541.00 43.26N
ATOM30C ARGA818.3106.7409.3141.0040.13C·ATOM31O ARGA819.3196.3208.7421.0040.05O
ATOM32N ASPA917.3237.3568.6521.00 39.15N
ATOM33CA ASPA917.4567.6947.2301.0037.79C
ATOM34CB ASPA916.1258.1716.6261.00 38.31C
ATOM35CG ASPA914.9307.3847.1101.00 39.78C
ATOM36ODl ASPA913.9628.0337.5681.0041.40O
ATOM37OD2ASPA914.9436.1357.0151.0041.38〇
ATOM38C ASPA918.4758.8237.0611.00 36.45C
ATOM39O ASPA918.9679.3718.0451.00 36.65O
ATOM40N PROA1018.7999.1845.8091.00 34.65N
ATOM41CA PROA1019.43310.483 5.6411.00 33.25C
ATOM42CB PROA1019.72910.528 4.1421.00 32.98C
ATOM43CG PROA1019.7799.089 3.7301.00 34.18C
ATOM44CD PROA1018.6928.465 4.5281.00 34.61C
ATOM45C PROA1018.50011.6366.0651.0031.38C
ATOM46O PROA1018.94712.7756.1551.0031.77O
ATOM47N LEUA1117.22511.3366.3161.0029.48N
ATOM48CA LEUA1116.27412.345 6.8131.00 27.68C
ATOM49CB LEUA1114.81611.916 6.5881,0026.63C
ATOM50CG LEUA1114.22311.864 5.1681.00 25.43C
ATOM51CDl LEUA1112.77011.4605.2291.0023.05C
ATOM52CD2LEUA1114.34613.1914.4241.0023.76C
ATOM53C LEUA1116.50012.6728.2881.0027.42C
ATOM54O LEUA1116.22613.7948.7301.0025.74O
ATOM55N VALA1216.97611.6959.0591.0027.11N
ATOM56CA VALA1217.27611.95510.4681.0027.10C
ATOM57CB VALA1217.00010.74211.4101.0027.47C
ATOM58CGl VALA1216.0299.76410.7811.0027.69C
ATOM59CG2 VALA1218.28710.04911.8201.0028.05C
ATOM60C VALA1218.69712.47410.6051.0027.02C
ATOM61O VALA1218.94313.37811.3991.0026.52O
ATOM62N VALA1319.61911.9209.8131.0026.34N
ATOM63CA VALA1320.97412.455 9.6881.0026.40C
ATOM64CB VALA1321.83211.636 8.6721.0026.94C
ATOM65CGl VALA1323.01612.4468.1541.0027.65C
ATOM66CG2VALA1322.31410.3499.2951.00 27.69C
[0567]ATOM67C VALA 1320.891 13.9179.2391.0025.34CATOM68O VALA 1321.604 14.7829.7581.0025.67O
ATOM69N GLYA 1420.002 14.1868.2791.00 24.50N
ATOM70CA GLYA 14 19.808 15.539 7.7631.0022.95C
ATOM71C GLYA 1418.975 16.4408.6561.0021.25C
ATOM72O GLYA 1418.804 17.6198.3431.0021.51O
ATOM73N ARGA 1518.471 15.8909.7631.0020.71N
ATOM74CA ARGA 15 17.691 16.62410.770 1.0019.32C·ATOM75CB ARGA 15 18.516 17.75711.4191.0019.74C
ATOM76CG ARGA 15 19.854 17.33712.057 1.00 22.06C
ATOM77CD ARGA 15 19.672 16.14912.9711.0027.33C
ATOM78NE ARGA 15 20.898 15.78813.6771.0031.03N
ATOM79CZ ARGA 1521.086 14.63814.3261.00 32.99C
ATOM80NHl ARGA 1520.134 13.70814.3571.0033.51N
ATOM81NH2ARGA 1522.236 14.41314.9401.00 34.74N
ATOM82C ARGA 1516.344 17.15810.2561.0018.54C
ATOM83O ARGA 1515.694 17.97710.9151.0016.85O
ATOM84N VALA 1615.926 16.6769.0881.0017.20N
ATOM85CA VALA 1614.594 16.981 8.5541.0016.42C
ATOM86CB VALA 1614.452 16.4977.1111.0016.16C
ATOM87CGl VALA 1613.025 16.6786.6181.0015.31C
ATOM88CG2VALA 1615.429 17.2286.1981.0016.22C
ATOM89C VALA 1613.529 16.3399.4381.00 16.42C
ATOM90O VALA 1612.586 17.0079.8611.0014.92O
ATOM91N VALA 1713.699 15.0429.7411.0017.05N
ATOM92CA VALA 1712.971 14.42910.8361.0018.33C
ATOM93CB VALA 1712.979 12.88010.7761.0018.85C
ATOM94CGl VALA 1712.460 12.29712.0901.00 20.27C
ATOM95CG2VALA 1712.130 12.3989.5921.0019.66C
ATOM96C VALA 1713.664 14.95812.0961.00 18.52C
ATOM97O VALA 1714.863 14.72512.2921.0019.61O
ATOM98N GLYA 1812.908 15.69912.9021.0018.19N
ATOM99CA GLYA 1813.460 16.49613.9841.0018.34C
ATOM100C GLYA 1813.054 17.95013.8141.0017.75C
ATOM101O GLYA 1812.180 18.44114.5311.0019.12O
ATOM102N ASPA 1913.671 18.63612.8541.0016.90N
ATOM103CA ASPA 1913.386 20.05712.6541.0015.56C
ATOM104CB ASPA 1914.466 20.72511.8101.0015.27C
ATOM105CG ASPA 1915.803 20.82512.5211.0015.22C
ATOM106ODl ASPA 1915.879 20.65013.7631.00 18.15O
ATOM107OD2ASPA 1916.786 21.09011.8141.0014.86O
ATOM108C ASPA 1912.040 20.30911.9911.0014.92C
ATOM109O ASPA 1911.388 21.29812.2921.0016.18O
ATOM110N VALA 2011.630 19.41811.0931.0013.95N
[0568]ATOM111CA VALA 2010.42219.67610.3061.0013.45CATOM112CB VALA 2010.76119.793 8.8041.0012.68C
ATOM113CGl VALA 209.49020.0287.9911.0011.79C
ATOM114CG2VALA 2011.78920.9078.5501.0014.23C
ATOM115C VALA 209.38218.58310.4891.0013.69C
ATOM116O VALA 208.18418.86410.6071.00 13.87O
ATOM117N LEUA 219.86517.34210.5401.0014.73N
ATOM118CA LEUA 218.98716.19010.5561.0015.26C
ATOM119CB LEUA 219.16615.364 9.2771.0014.80C
ATOM120CG LEUA 218.94116.094 7.9451.0012.27C
ATOM121CDl LEUA 219.25115.1766.7941.0012.76C
ATOM122CD2LEUA 217.55416.6797.8231.0012.86C
ATOM123C LEUA 219.25315.30811.7521.0016.68C
ATOM124O LEUA 2110.35315.30312.3061.0016.92O
ATOM125N ASPA 228.21914.56312.1111.0017.80N
ATOM126CA ASPA 228.34613.44813.0391.00 19.01C
ATOM127CB ASPA 227.08313.33313.8821.0019.32C
ATOM128CG ASPA 226.98514.44014.9261.0020.48C
ATOM129ODl ASPA 228.03314.98615.3171.0024.05O
ATOM130OD2ASPA 225.86814.78215.3301.0023.30O
ATOM131C ASPA 228.60812.18612.2391.0020.19C
ATOM132O ASPA 228.46912.17311.0011.0020.87O
ATOM133N ALAA 239.00811.13012.9411.0020.00N
ATOM134CA ALAA 239.2539.82912.3381.0020.49C
ATOM135CB ALAA 239.5388.79513.4191.0020.19C
ATOM136C ALAA 238.0599.39511.5251.0019.62C
ATOM137O ALAA 236.9159.58411.9401.0020.07O
ATOM138N PHEA 248.3478.82710.3541.0020.67N
ATOM139CA PHEA 247.3108.2789.4751.00 21.24C
ATOM140CB PHEA 246.6919.3828.5731.0021.46C
ATOM141CG PHEA 247.5999.8787.4811.00 20.91C
ATOM142CDl PHEA 248.47510.9337.7141.0021.48C
ATOM143CEl PHEA 249.31811.3966.7041.0020.22C
ATOM144CZ PHEA 249.27310.8145.4431.00 20.95C
ATOM145CE2PHEA 248.3989.7725.1901.0020.11C
ATOM146CD2PHEA 247.5649.3086.2041.0020.15C
ATOM147C PHEA 247.8347.1048.6361.0021.22C
ATOM148O PHEA 249.0456.9338.4491.0022.17O
ATOM149N VALA 256.9176.3068.1081.0022.54N
ATOM150CA VALA 257.2915.2287.1861.00 23.16C
ATOM151CB VALA 256.7363.8317.6371.0023.86C
ATOM152CGl VALA 255.2853.9238.0931.0025.21C
ATOM153CG2VALA 256.9152.7826.5481.0024.61C
ATOM154C VALA 256.8975.6045.7491.00 22.57C
[0569]ATOM199CG LYSA 3111.93210.899 -9.662 1.00 15.89C
ATOM200CD LYSA 3111.8199.944-10.8381.00 19.52C
ATOM201CE LYSA 3112.92110.178-11.8441.00 22.81C
ATOM202NZ LYSA 3112.7899.222-12.9871.0027.06N
ATOM203C LYSA 3110.85413.156 -7.9351.0013.16C
ATOM204O LYSA 319.96613.601 -8.6581.0013.34O
ATOM205N VALA 3211.86013.882 -7.4581.0012.62N ATOM206CA VALA 3211.99815.309 -7.722 1.0011.96C
ATOM207CB VALA 3212.26416.078 -6.395 1.0011.66C
ATOM208CGl VALA 3212.47517.570 -6.6631.0011.11C
ATOM209CG2VALA 3211.13715.844 -5.4031.0011.90C
ATOM210C VALA 3213.19115.509 -8.6581.00 12.56C
ATOM211O VALA 3214.32615.142 -8.3141.0013.46O
ATOM212N THRA 3312.95616.076 -9.839 1.0011.70N
ATOM213CA THRA 3313.98816.182-10.858 1.0012.55C
ATOM214CB THRA 3313.74815.161-12.0191.0012.70C
ATOM215OGl THRA 3313.54213.854-11.4711.0013.48O
ATOM216CG2THRA 3314.91815.097-12.9781.0014.67C
ATOM217C THRA 3314.11617.599-11.3991.0011.41C
ATOM218O THRA 3313.14218.205-11.8541.0011.41O
ATOM219N TYRA 3415.33718.119-11.3431.0011.75N
ATOM220CA TYRA 3415.69819.371-11.9591.0012.44C
ATOM221CB TYRA 3416.52020.211-10.9951.00 12.68C
ATOM222CG TYRA 3415.75620.795 -9.820 1.0010.94C
ATOM223CDl TYRA 3415.05721.978 -9.959 1.0011.31C
ATOM224CEl TYRA 3414.37822.546 -8.8801.00 9.98C
ATOM225CZ TYRA 3414.43221.943 -7.660 1.0011.59C
ATOM226OH TYRA 3413.78722.548 -6.589 1.0010.34O
ATOM227CE2TYRA 3415.13820.768 -7.4791.0011.29C
ATOM228CD2TYRA 3415.80620.193 -8.5701.0011.35C
ATOM229C TYRA 3416.55119.057-13.1781.0013.57C
ATOM230O TYRA 3417.66418.553-13.0291.0013.66O
ATOM231N GLYA 3516.03319.344-14.3741.0013.84N
ATOM232CA GLYA 3516.73218.958-15.6161.00 15.18C
ATOM233C GLYA 3516.80017.440-15.7051.0016.38C
ATOM234O GLYA 3515.77516.761 -15.7851.0016.96O
ATOM235N SERA 3618.01016.896-15.6621.0017.77N
ATOM236CA SERA 3618.15015.438-15.6031.0018.97C
ATOM237CB SERA 3619.09014.942-16.6961.00 19.64C
ATOM238OG SERA 3620.38515.464-16.5061.0021.57O
ATOM239C SERA 3618.63714.949-14.2381.0019.73C
ATOM240O SERA 3618.90313.764-14.0471.0020.43O
ATOM241N LYSA 3718.72815.869-13.2811.0019.10N
ATOM242CA LYSA 3719.24115.559-11.9501.0020.22C
[0571]ATOM243CB LYSA3720.02316.752-11.3821.0019.94CATOM244CG LYSA3721.14717.305 -12.2411.0023.65C
ATOM245CD LYSA3721.71818.564-11.5841.0023.68C
ATOM246CE LYSA3722.72919.279-12.4711.00 28.46C
ATOM247NZ LYSA3723.99118.497-12.6351.0029.30N
ATOM248C LYSA3718.10015.234-10.9991.0019.27C
ATOM249O LYSA3717.36716.135-10.5801.0017.57O
ATOM250N THRA3817.95813.963-10.6401.0018.79N·ATOM251CA THRA38 17.002 13.549 -9.619 1.00 18.53C
ATOM252CB THRA3816.510 12.088 -9.837 1.0019.21C
ATOM253OGl THRA3815.76612.018-11.0641.0019.55O
ATOM254CG2THRA3815.62011.605 -8.6781.0019.05C
ATOM255C THRA3817.58913.750 -8.2201.0018.54C
ATOM256O THRA3818.71613.357 -7.9421.0019.06O
ATOM257N YALA3916.82314.387 -7.3421.0016.92N
ATOM258CA VALA3917.25614.629 -5.9641.0017.12C
ATOM259CB VALA3916.29615.651 -5.2831.0016.75C
ATOM260CGl VALA3916.60115.836 -3.7891.0017.52C
ATOM261CG2VALA3916.35016.980 -6.0171.0015.54C
ATOM262C VALA3917.31513.338 -5.1481.0017.46C
ATOM263O VALA3916.39012.541 -5.1641.0017.06O
ATOM264N SERA4018.42413.136 -4.4351.0017.68N
ATOM265CA SERA4018.44112.193 -3.3151.0018.58C
ATOM266CB SERA4019.39711.027 -3.5521.0019.00C
ATOM267OG SERA4020.69211.505 -3.7971.0021.47O
ATOM268C SERA4018.84312.987 -2.0751.0017.60C
ATOM269O SERA4019.44814.046 -2.2091.0018.01O
ATOM270N ASNA4118.49612.470 -0.9011.0018.90N
ATOM271CA ASNA4]18.746 13.150 0.374 1.0018.58C
ATOM272CB ASNA4118.37012.236 1.538 1.00 18.85C
ATOM273CG ASNA4116.874 12.043 1.670 1.00 18.46C
ATOM274ODl ASNA4116.38110.933 1.8251.0021.16O
ATOM275ND2ASNA4116.13713.139 1.6141.0015.79N
ATOM276C ASNA4120.17713.638 0.5351.0019.52C
ATOM277O ASNA4121.11712.846 0.4321.0020.11O
ATOM278N GLYA4220.34214.941 0.7631.0019.59N
ATOM279CA GLYA4221.66315.520 1.022 1.0020.73C
ATOM280C GLYA4222.41415.963 -0.2181.0021.31C
ATOM281O GLYA4223.46016.626 -0.1211.0022.32O
ATOM282N LEUA4321.88715.603 -1.3881.0021.41N
ATOM283CA LEUA4322.44216.031 -2.6611.0021.73C
ATOM284CB LEUA4321.51715.623 -3.8101.00 22.13C
ATOM285CG LEUA4321.984 15.984 -5.2231.0022.38C
ATOM286CDl LEUA4323.23815.189 -5.6091.0021.96C[0572]ATOM287CD2LEUA 43 20.87115.734 -6.233 1.0022.92C
ATOM288C LEUA 43 22.64617.538 -2.690 1.0021.61C
ATOM289O LEUA 43 21.73318.301 -2.371 1.0020.99O
ATOM290N GLUA 44 23.84417.978 -3.044 1.0021.67N
ATOM291CA GLUA 44 24.07119.398 -3.182 1.0021.58C
ATOM292CB GLUA 44 25.510 19.795 -2.838 1.0022.31C
ATOM293CG GLUA 44 25.767 21.264 -3.143 1.0023.85C
ATOM294CD GLUA 44 26.898 21.869 -2.338 1.0026.59C
ATOM295OEl GLUA 44 27.68921.117 -1.717 1.00 28.58O
ATOM296OE2GLUA 44 26.98923.108 -2.334 1.00 27.92O
ATOM297C GLUA 44 23.70919.854 -4.577 1.0021.63C
ATOM298O GLUA 44 24.17319.290 -5.574 1.0021.73O
ATOM299N LEUA 45 22.85620.871 -4.648 1.0021.04N
ATOM300CA LEUA 45 22.52821.507 -5.914 1.0020.48C
ATOM301CB LEUA 45 21.04921.313 -6.277 1.0020.50C
ATOM302CG LEUA 45 20.59319.903 -6.656 1.0019.35C
ATOM303CDl LEUA 45 19.07119.851 -6.802 1.00 18.58C
ATOM304CD2LEUA 45 21.26919.409 -7.938 1.0021.10C
ATOM305C LEUA 45 22.85322.981 -5.857 1.00 20.71C
ATOM306O LEUA 45 22.69423.618 -4.808 1.0021.18O
ATOM307N LYSA 46 23.34323.520 -6.970 1.0020.32N
ATOM308CA LYSA 46 23.61624.949 -7.055 1.00 20.19C
ATOM309CB LYSA 46 24.57125.284 -8.209 1.0021.02C
ATOM310CG LYSA 46 25.89524.535 -8.156 1.00 23.71C
ATOM311CD LYSA 46 26.97925.263 -8.955 1.0028.47C
ATOM312CE LYSA 46 26.48625.721 -10.324 1.00 30.79C
ATOM313NZ LYSA 46 27.44226.682-10.955 1.00 32.21N
ATOM314C LYSA 46 22.30925.705 -7.222 1.0019.43C
ATOM315O LYSA 46 21.38525.207 -7.870 1.00 18.78O
ATOM316N PROA 47 22.21926.915 -6.648 1.0019.03N
ATOM317CA PROA 47 21.03627.749 -6.838 1.0019.24C
ATOM318CB PROA 47 21.46829.098 -6.242 1.0019.42C
ATOM319CG PROA 47 22.42928.721 -5.192 1.0019.39C
ATOM320CD PROA 47 23.20127.563 -5.759 1.0019.56C
ATOM321C PROA 47 20.60227.882 -8.311 1.0018.88C
ATOM322O PROA 47 19.40327.843 -8.608 1.0018.80O
ATOM323N SERA 48 21.55328.041 -9.235 1.0019.58N
ATOM324CA SERA 48 21.21128.192-10.651 1.0019.51C
ATOM325CB SERA 48 22.46828.474-11.486 1.0020.07C
ATOM326OG SERA 48 23.32027.347-11.455 1.0022.63O
ATOM327C SERA 48 20.47326.977-11.226 1.0019.17C
ATOM328O SERA 48 19.76727.096 -12.216 1.0019.62O
ATOM329N META 49 20.65325.812-10.617 1.0018.45N
ATOM330CA META 49 19.988 24.603-11.080 1.00 18.55C
[0573]ATOM331CB ΜΕΤΑ 49 20.745 23.363 -10.589 1.0018.68CATOM332CG ΜΕΤΑ 49 22.172 23.209-11.148 1.00 20.25C
ATOM333SD ΜΕΤΑ 49 23.138 22.099-10.126 1.0023.81S
ATOM334CE ΜΕΤΑ 49 24.770 22.202-10.862 1.0022.41C
ATOM335C ΜΕΤΑ 49 18.523 24.533 -10.645 1.0017.01C
ATOM336O ΜΕΤΑ 49 17.742 23.780-11.216 1.0016.05O
ATOM337N VALA 50 18.156 25.331 -9.644 1.0014.99N
ATOM338CA VALA 50 16.839 25.205 -8.993 1.00 13.94C
ATOM339CB YALA 50 16.974 24.654 -7.542 1.0012.87C
ATOM340CGl VALA 50 17.667 23.304 -7.565 1.0013.50C
ATOM341CG2VALA 50 17.724 25.622 -6.631 1.0014.15C
ATOM342C VALA 50 15.977 26.468 -9.071 1.0012.86C
ATOM343O VALA 50 15.020 26.634 -8.300 1.0012.24O
ATOM344N THRA 51 16.289 27.345-10.018 1.00 13.48N
ATOM345CA THRA 51 15.551 28.596-10.204 1.0013.59C
ATOM346CB THRA 51 16.220 29.446-11.302 1.0014.31C
ATOM347OGl THRA 51 16.404 28.628-12.463 1.0016.31O
ATOM348CG2THRA 51 17.574 29.940 -10.845 1.0014.50C
ATOM349C THRA 51 14.060 28.386-10.544 1.0013.98C
ATOM350O THRA 51 13.204 29.184-10.159 1.0014.64O
ATOM351N HISA 52 13.754 27.313-11.276 1.0013.33N
ATOM352CA HISA 52 12.386 26.982-11.647 1.00 13.04C
ATOM353CB HTSA 52 12.282 26.832-13.151 1.00 13.68C
ATOM354CG HISA 52 12.477 28.114-13.884 1.0014.46C
ATOM355NDl HISA 52 13.708 28.721 -14.014 1.00 16.14N
ATOM356CEl HISA 52 13.565 29.843 -14.699 1.0016.08C
ATOM357NE2HISA 52 12.291 29.983-15.011 1.0018.18N
ATOM358CD2HISA 52 11.588 28.920-14.500 1.0015.40C
ATOM359C fflSA 52 11.971 25.678-10.991 1.0011.09C
ATOM360O HISA 52 12.821 24.887 -10.577 1.0011.88O
ATOM361N GLNA 53 10.662 25.453 -10.916 1.0011.62N
ATOM362CA GLNA 53 10.182 24.293-10.182 1.0011.19C
ATOM363CB GLNA 53 8.651 24.285 -10.044 1.0010.34C
ATOM364CG GLNA 53 7.900 24.105-11.336 1.0011.51C
ATOM365CD GLNA 53 6.494 24.537-11.186 1.0015.07C
ATOM366OEl GLNA 53 6.220 25.739-11.055 1.0015.59O
ATOM367NE2GLNA 53 5.583 23.584-11.193 1.0014.39N
ATOM368C GLNA 53 10.667 22.995-10.820 1.0010.53C
ATOM369O GLNA 53 10.759 22.893 -12.064 1.0011.42O
ATOM370N PROA 54 10.977 21.992 -9.983 1.0010.57N
ATOM371CA PROA 54 11.353 20.695-10.519 1.0010.47C
ATOM372CB PROA 54 11.933 19.974 -9.312 1.0010.85C
ATOM373CG PROA 54 11.188 20.546 -8.128 1.0010.74C
ATOM374CD PROA 54 10.947 22.001 -8.499 1.00 9.97C
[0574]ATOM375C PROA 5410.12819.932-10.9891.00 11.10CATOM376O PROA 548.97720.289-10.6641.0011.18O
ATOM377N ARGA 5510.36218.893-11.7791.00 11.44N
ATOM378CA ARGA 55 9.30517.929-12.0421.0012.31C
ATOM379CB ARGA 55 9.64817.104-13.2671.0013.37C
ATOM380CG ARGA 55 9.55317.863 -14.5551.0016.91C
ATOM381CD ARGA 55 9.59116.900-15.7321.0019.52C
ATOM382NE ARGA 5510.78816.061 -15.6781.00 21.39N· ATOM383CZ ARGA 5512.02116.508-15.8831.00 20.16C
ATOM384NHl ARGA 5512.23817.792-16.1571.00 22.79N
ATOM385NH2ARGA 5513.04915.669-15.8061.0021.29N
ATOM386C ARGA 559.19117.027-10.8411.0012.50C
ATOM387O ARGA 5510.20116.551 -10.3281.0012.92O
ATOM388N VALA 567.97816.792-10.3661.0011.65N
ATOM389CA VALA 567.79815.967 -9.1781.0011.93C
ATOM390CB VALA 567.37116.797 -7.9521.00 12.02C
ATOM391CGl VALA 567.20915.940 -6.7231.00 12.50C
ATOM392CG2VALA 568.39317.899 -7.6781.0011.26C
ATOM393C VALA 566.79714.888 -9.4871.0013.55C
ATOM394O VALA 565.59515.142 -9.5101.0013.06O
ATOM395N GLUA 577.31913.690 -9.7341.0013.98N
ATOM396CA GLUA 57 6.48912.547-10.0351.0015.76C
ATOM397CB GLUA 57 7.23111.563-10.9461.0015.61C
ATOM398CG GLUA 57 7.44912.137-12.3261.00 16.98C
ATOM399CD GLUA 57 8.19211.204-13.2911.0019.08C
ATOM400OEl GLUA 578.3599.998 -12.9901.0024.85O
ATOM401OE2GLUA 578.58911.703-14.3701.0025.69O
ATOM402C GLUA 576.07911.914 -8.7371.0015.53C
ATOM403O GLUA 576.87211.803 -7.7951.00 15.86O
ATOM404N VALA 584.80411.548 -8.6661.0015.80N
ATOM405CA VALA 584.28710.872 -7.4881.0017.11C
ATOM406CB VALA 583.14411.638 -6.7671.0017.67C
ATOM407CGl VALA 583.57713.081 -6.4511.0016.49C
ATOM408CG2VALA 581.84311.613 -7.5631.0019.47C
ATOM409C VALA 583.8469.466 -7.8631.0017.01C
ATOM410O VALA 583.2209.241 -8.9231.0017.90O
ATOM411N GLYA 594.1828.529 -6.9941.0016.97N
ATOM412CA GLYA 593.7877.144 -7.1791.0017.19C
ATOM413C GLYA 592.3766.870 -6.6951.0017.33C
ATOM414O GLYA 591.4387.647 -6.9321.00 16.56O
ATOM415N GLYA 602.2245.744 -6.0081.0018.31N
ATOM416CA GLYA 600.9095.284 -5.5861.0019.22C
ATOM417C GLYA 600.2594.294 -6.5571.0020.17C
ATOM418O GLYA 600.8853.886 -7.5461.0020.71O [0575]ATOM419N ASNA61 -0.9933.931 -6.264 1.00 20.95N
ATOM420CA ASNA61 -1.7252.864 -6.968 1.0022.07C
ATOM421CB ASNA61 -2.7852.245 -6.045 1.0022.28C ATOM422CG ASNA61 -2.2441.112 -5.205 1.00 25.63C
ATOM423ODl ASNA61 -1.5240.248 -5.695 1.0028.95O
ATOM424ND2ASNA61 -2.6121.096 -3.935 1.0028.97N
ATOM425C ASNA61 -2.4353.335 -8.218 1.0021.66C
ATOM426O ASNA61 -2.4802.617 -9.221 1.00 22.35O
ATOM427N ASPA62 -3.0444.515 -8.137 1.0021.12N
ATOM428CA ASPA62 -3.8455.041 -9.237 1.0021.14C
ATOM429CB ASPA62 -5.1134.184 -9.483 1.0021.61C
ATOM430CG ASPA62 -6.0474.134 -8.274 1.0022.61C
ATOM431ODl ASPA62 -6.5805.188 -7.876 1.0024.91O
ATOM432OD2ASPA62 -6.2873.023 -7.746 1.0024.60O
ATOM433C ASPA62 -4.1986.506 -9.049 1.0020.60C
ATOM434O ASPA62 -3.8907.115 -8.023 1.0019.85O
ATOM435N META63 -4.8627.052-10.061 1.0019.74N
ATOM436CA META 63 -5.1558.482-10.132 1.0019.71C
ATOM437CB META63 -5.4628.876-11.578 1.0019.87C
ATOM438CG META 63 -4.2528.824-12.474 1.0019.72C
ATOM439SD META63 -4.6419.187-14.196 1.0023.34S
ATOM440CE META63 -5.23910.851 -14.073 1.0023.23C
ATOM441C META63 -6.2798.949 -9.219 1.0018.85C
ATOM442O META63 -6.58310.142 -9.183 1.00 18.07O
ATOM443N ARGA64 -6.9088.023 -8.496 1.00 18.97N
ATOM444CA ARGA 64 -8.0168.387 -7.616 1.0018.87C
ATOM445CB ARGA64 -9.1807.387 -7.736 1.0019.18C
ATOM446CG ARGA 64 -9.8367.376 -9.104 1.0021.09C
ATOM447CD ARGA 64-11.0636.463 -9.113 1.0021.95C
ATOM448NE ARGA64-12.2687.086 -8.552 1.00 26.78N
ATOM449CZ ARGA64-12.8276.756 -7.387 1.0028.44C
ATOM450NHl ARGA64 -12.3005.797 -6.628 1.0029.72N
ATOM451NH2ARGA64-13.9307.383 -6.977 1.00 30.04N
ATOM452C ARGA64 -7.5668.560 -6.164 1.00 18.10C
ATOM453O ARGA64 -8.3798.828 -5.282 1.0017.60O
ATOM454N THRA65 -6.2658.402 -5.928 1.0016.62N
ATOM455CA THRA65 -5.6548.824 -4.671 1.0016.22C
ATOM456CB THRA65 -4.6077.817 -4.152 1.0016.94C
ATOM457OGl THRA65 -5.2466.567 -3.857 1.0019.49O
ATOM458CG2THRA65 -3.9558.323 -2.872 1.0018.53C
ATOM459C THRA65 -4.98510.164 -4.948 1.0014.81C
ATOM460O THRA65 -4.32910.331 -5.994 1.00 15.24O
ATOM461N PHEA66 -5.15711.106 -4.021 1.0013.11N
ATOM462CA PHEA66 -4.63012.459 -4.197 1.0012.59C
[0576]ATOM463CB PHEA 66-5.76813.486-4.2081.0013.15CATOM464 CG PHEA 66-6.74013.272-5.3181.0014.50C
ATOM465CDl PHEA 66-6.50713.820-6.5731.0014.94C
ATOM466CEl PHEA 66-7.39813.585-7.6351.0017.78C
ATOM467 CZ PHEA 66-8.52712.785-7.4241.00 17.85C
ATOM468CE2PHEA 66-8.76012.220-6.1741.0018.68C
ATOM469CD2PHEA 66-7.85512.454-5.1261.0016.22C
ATOM470C PHEA 66-3.59912.811-3.1431.0012.46C·ATOM471O PHEA 66-3.70712.405-1.9871.0012.11O
ATOM472N TYRA 67-2.62613.621-3.5641.0011.47N
ATOM473CA TYRA 67-1.48613.976-2.7401.0010.69C
ATOM474CB TYRA 67-0.23113.287-3.2831.00 11.54C
ATOM475CG TYRA 67-0.29911.783-3.2581.0012.17C
ATOM476CDl TYRA 67-0.78911.084-4.3561.0012.88C
ATOM477CEl TYRA 67-0.8639.696-4.3441.0015.49C
ATOM478CZ TYRA 67-0.4679.007-3.2291.0014.40C
ATOM479OH TYRA 67-0.5447.623-3.2521.00 16.14O
ATOM480CE2TYRA 670.0309.669-2.1081.0013.73C
ATOM481CD2TYRA 670.09611.058-2.1271.0012.45C
ATOM482C TYRA 67-1.25915.485-2.6451.0010.61C
ATOM483O TYRA 67-1.55716.247-3.5781.0010.82O
ATOM484N THRA 68-0.70415.890-1.5051.0010.52N
ATOM485CA THRA 68-0.26317.277-1.2821.0010.36C
ATOM486CB THRA 68-0.90817.865-0.0221.0010.43C
ATOM487OGl THRA 68-2.26718.195-0.3291.0010.77O
ATOM488CG2THRA 68-0.18719.1430.4441.0011.32C
ATOM489C THRA 681.25317.302-1.1661.00 9.84C
ATOM490O THRA 681.84216.490-0.4631.0010.24O
ATOM491N LEUA 691.86518.253-1.8771.00 9.28N
ATOM492CA LEUA 693.30418.502-1.8701.00 8.99 C
ATOM493CB LEUA 693.86218.468-3.2941.00 9.04 C
ATOM494CG LEUA 695.35818.743-3.4191.0010.30C
ATOM495CDl LEUA 696.15917.556-2.9451.0011.75C
ATOM496CD2LEUA 695.68319.017-4.8701.0010.37C
ATOM497C LEUA 693.60519.862-1.2441.00 8.91C
ATOM498O LEUA 693.05320.894-1.6501.00 9.05O
ATOM499N VALA 704.49219.828-0.2541.00 8.68N
ATOM500CA YALA 704.98220.9940.4721.00 8.66 C
ATOM501CB VALA 704.81120.7861.9821.00 8.76 C
ATOM502CGl VALA 705.42821.9672.7651.0011.73C
ATOM503CG2VALA 703.34520.5832.3201.0011.81C
ATOM504C VALA 706.46421.1170.2071.00 7.88C
ATOM505O VALA 707.18820.1350.3141.00 8.44O
ATOM506N META 716.93522.326-0.0791.00 8.16 N
[0577]ATOM507CA ΜΕΤΑ 718.375 22.575-0.1621.00 7.63 CATOM508CB ΜΕΤΑ 718.801 22.859-1.6051.00 7.87 C
ATOM509CG ΜΕΤΑ 7110.298 23.096-1.7631.00 8.73 C
ATOM510SD ΜΕΤΑ 7110.624 23. 912-3.3391.00 8.90 S
ATOM511CE ΜΕΤΑ 7112.412 24.075-3.2721.0010.72C
ATOM512C ΜΕΤΑ 718.737 23.7190.7611.00 6.96C
ATOM513O ΜΕΤΑ 718.220 24.8330.6061.00 7.60 O
ATOM514N VALA 729.636 23.4411.7141.00 7.01N
ATOM515CA VALA 7210.044 24.4472.7111.00 7.91 C
ATOM516CB VALA 729.396 24.1784.1051.00 7.93 C
ATOM517CGl VALA 727.883 24.3464.0401.0010.28C
ATOM518CG2VALA 729.742 22.7694.6251.00 9.84C
ATOM519C VALA 7211.557 24.5522.8841.00 8.26C
ATOM520O VALA 7212.276 23.5862.6281.00 8.13O
ATOM521N ASPA 7312.011 25.7433.2981.00 8.24N
ATOM522CA ASPA 7313.401 25.9743.7371.00 8.48 C
ATOM523CB ASPA 7314.015 27.1753.0291.00 9.04C
ATOM524CG ASPA 7315.486 27.3913.3791.0010.14C
ATOM525ODl ASPA 7316.011 26.7214.2801.00 9.98O
ATOM526OD2ASPA 7316.088 28.2752.7471.0012.13O
ATOM527C ASPA 7313.346 26.2115.2471.00 8.65C
ATOM528O ASPA 7312.906 27.2525.7031.00 9.12O
ATOM529N PROA 7413.782 25.2266.0331.00 9.39N
ATOM530CA PROA 7413.805 25.4097.4891.00 9.78 C
ATOM531CB PROA 7413.891 23.9787.9991.0010.36C
ATOM532CG PROA 7414.702 23.2806.9611.00 9.48 C
ATOM533CD PROA 7414.228 23.8695.6421.00 9.67 C
ATOM534C PROA 7415.026 26.2037.9611.00 10.88C
ATOM535O PROA 7415.128 26.5139.1551.0011.53O
ATOM536N ASPA 7515.911 26.5507.0241.0011.03N
ATOM537CA ASPA 7517.165 27.2607.3111.0011.09C
ATOM538CB ASPA 7518.338 26.5116.6591.0011.39C
ATOM539CG ASPA 7518.491 25.1197.1951.0011.34C
ATOM540ODl ASPA 7518.436 24.9728.4201.0013.96O
ATOM541OD2ASPA 7518.635 24.1296.4301.0013.93O
ATOM542C ASPA 7517.140 28.7036.8301.0011.19C
ATOM543O ASPA 7518.185 29.2426.4821.0012.38O
ATOM544N ALAA 7615.955 29.3166.7931.00 11.30N
ATOM545CA ALAA 7615.777 30.6696.2741.0012.10C
ATOM546CB ALAA 7614.511 30.7405.4051.0012.47C
ATOM547C ALAA 7615.685 31.6907.4121.0012.33C
ATOM548O ALAA 7614.973 31.4648.3891.00 12.27O
ATOM549N PROA 7716.405 32.8217.3001.00 13.41N
ATOM550CA PROA 7717.378 33.2016.2641.0013.79C
[0578]ATOM551CBPROA77 17.55634.7186.5001.0014.09CATOM552CGPROA 77 16.41735.1307.4231.0015.20C
ATOM553CDPROA 77 16.20233.9108.2711.0013.53C
ATOM554CPROA77 18.73932.4806.3231.0014.46C
ATOM555OPROA77 19.44932.4455.3181.00 14.37O
ATOM556NSERA78 19.10031.9177.4741.00 14.30N
ATOM557CASERA78 20.38131.2267.6461.0015.55C ATOM558CBSERA78 21.39432.1668.3071.0016.01C
ATOM559OGSERA78 22.59131.4968.6661.0020.32O
ATOM560CSERA78 20.21430.0128.5321.0014.81C
ATOM561OSERA78 19.42830.0509.4771.0013.88O
ATOM562NPROA79 20.98128.9318.2771.0015.25N
ATOM563CAPROA79 20.89227.8179.2191.0015.73C
ATOM564CBPROA79 21.82126.7538.6201.0015.83C
ATOM565CGPROA79 22.71827.4907.6831.0015.98C
ATOM566CDPROA79 21.91128.6487.1661.0015.07C
ATOM567CPROA79 21.31228.19610.6461.00 15.88C
ATOM568OPROA79 20.82627.60811.6011.0016.58O
ATOM569NSERA80 22.17529.19710.7911.0016.07N
ATOM570CASERA80 22.58529.63112.1401.0016.19C
ATOM571CBSERA80 24.03530.10512.1161.0017.04C
ATOM572OGSERA80 24.13231.28811.3701.0017.95O
ATOM573CSERA80 21.67630.71312.7461.0016.20C
ATOM574OSERA80 21.84831.10713.9001.0015.71O
ATOM575NASPA81 20.69131.17011.9781.0015.78N
ATOM576CAASPA81 19.70332.13712.4451.00 15.53C
ATOM577CBASPA81 20.24533.56212.2781.0017.12C
ATOM578CGASPA81 19.26534.64612.7251.00 19.91C
ATOM579ODl ASPA81 18.21134.36313.3381.0020.54O
ATOM580OD2ASPA81 19.57535.82012.4441.00 26.03O
ATOM581CASPA81 18.40931.91111.6331.0014.33C
ATOM582OASPA81 18.04832.71010.7751.0014.61O
ATOM583NPROA82 17.72530.79111.8931.0013.32N
ATOM584CAPROA82 16.58030.41411.0551.0012.43C
ATOM585CBPROA82 16.51328.89511.2471.0012.84C
ATOM586CGPROA82 16.98928.68712.6701.0012.18C
ATOM587CDPROA82 18.02129.77112.9221.0013.84C
ATOM588CPROA82 15.27331.07211.4901.0012.14C
ATOM589OPROA82 14.2713039311.7281.0011.56O
ATOM590NASNA83 15.27232.40111.5711.00 11.82N
ATOM591CAASNA83 14.12833.10812.156 1.0012.00C
ATOM592CBASNA83 14.50834.54412.5601.0012.64C
ATOM593CGASNA 83 14.97135.37511.3981.0013.45C
ATOM594ODl ASNA83 14.17735.74910.5301.00 15.06O
[0579]ATOM595ND2ASNA8316.27335.68611.3651.0014.12NATOM 596C ASNA8312.84433.10111.3221.0012.24C
ATOM 597O ASNA8311.77233.44511.8311.0012.21O
ATOM 598N LEUA8412.96332.68810.0621.0011.14N
ATOM599CA LEUA8411.78532.5389.1991.0010.21C
ATOM600CB LEUA8412.02533.1587.8231.0011.50C
ATOM601CG LEUA8412.37334.6577.770 1.0011.33C ATOM602CDl LEUA8412.58935.0636.3271.00 15.59C
ATOM603CD2LEUA8411.29735.4978.4661.0012.96C
ATOM604C LEUA8411.34431.0839.0531.0010.32C
ATOM605O LEUA8410.45430.7928.2371.00 9.88O
ATOM606N ARGA8511.95230.1779.8151.0010.23N
ATOM607CA ARGA 85 11.59328.7619.745 1.00 9.62 C
ATOM608CB ARGA 85 12.31227.96310.847 1.0010.21C
ATOM609CG ARGA 85 11.84426.50810.923 1.0010.25C
ATOM610CD ARGA 85 12.64425.72911.960 1.0012.94C
ATOM611NE ARGA8514.02925.57711.550 1.0012.84N
ATOM612CZ ARGA8514.94924.92112.249 1.0016.33C
ATOM613NHl ARGA8514.63224.36513.4201.00 18.08N
ATOM614NH2ARGA8516.18424.83611.7651.0016.17N
ATOM615C ARGA8510.10728.5629.9711.00 8.80C
ATOM616O ARGA85 9.59129.07710.9491.0010.26O
ATOM617N GLUA86 9.40927.7929.1291.00 8.68N
ATOM618CA GLUA86 9.85227.2897.8221.00 8.00C
ATOM619CB GLUA86 9.14625.9547.5211.00 8.19C
ATOM620CG GLUA86 9.42824.8618.5591.00 9.10C
ATOM621CD GLUA86 8.34223.7948.6741.00 9.77C
ATOM622OEl GLUA86 7.51023.6437.7621.00 11.38O
ATOM623OE2GLUA86 8.32023.1049.7251.0012.78O
ATOM624C GLUA86 9.43728.2746.7421.00 7.90C
ATOM625O GLUA86 8.31928.7666.7861.00 8.50O
ATOM626N TYRA8710.29228.5395.7541.00 7.01N
ATOM627CA TYRA87 9.86929.4274.6721.00 7.34C
ATOM628CB TYRA8711.01130.3354.1561.00 7.65C
ATOM629CG TYRA8710.51531.3643.1741.00 7.73C
ATOM630CDl TYRA8710.06132.6023.6241.00 8.89C
ATOM631CEl TYRA879.54333.5482.7271.00 9.48C
ATOM632CZ TYRA87 9.52533.2511.3701.00 9.35C
ATOM633OH TYRA87 9.04734.1700.4751.00 11.45O
ATOM634CE2TYRA879.99232.0120.9101.00 8.08C
ATOM635CD2TYRA8710.46931.0851.8081.00 8.96C
ATOM636C TYRA879.23728.5853.5561.00 6.85C
ATOM637O TYRA87 9.87127.6793.0141.00 7.21O
ATOM638N LEUA887.98928.8733.2221.00 7.27N[0580]ATOM639CA LEUA 887.232 28.0622.268 1.00 7.42C
ATOM640CB LEUA 885.731 28.2062.569 1.00 7.51C
ATOM641CG LEUA 884.811 27.4081.644 1.00 6.76C
ATOM642CDl LEUA 885.041 25.8891.840 1.00 8.93C
ATOM643CD2LEUA 883.353 27.7781.883 1.00 8.72C
ATOM644C LEUA 887.555 28.4580.8321.00 7.42C
ATOM645O LEUA 887.187 29.5570.384 1.00 7.91O
ATOM646N HISA 898.248 27.5660.1171.00 6.48N
ATOM647CA HISA 898.633 27.804-1.2761.00 7.32C
ATOM648CB HISA 899.973 27.151-1.5941.00 7.14C
ATOM649CG HISA 8911.147 27.951-1.1171.00 7.90C
ATOM650NDl HISA 8911.797 28.857-1.9261.00 9.32N
ATOM651CEl HISA 8912.759 29.446-1.2311.00 9.87C
ATOM652NE2 fflSA 8912.744 28.968-0.0031.00 9.07N
ATOM653CD2HISA 8911.732 28.0380.1021.00 9.94C
ATOM654C fflSA 897.615 27.386-2.3281.00 7.51C
ATOM655O HISA 897.616 27.948-3.4211.00 9.17O
ATOM656N TRPA 906.740 26.429-2.0071.00 8.06N
ATOM657CA TRPA 905.845 25.845-3.0121.00 7.76C
ATOM658CB TRPA 906.687 24.975-3.9541.00 7.32C
ATOM659CG TRPA 906.069 24.527-5.2411.00 8.01C
ATOM660CDl TRPA 905.055 25.112-5.9671.00 8.69C
ATOM661NEl TRPA 904.816 24.372-7.1131.00 9.57N
ATOM662CE2TRPA 905.704 23.322-7.1551.00 8.74C
ATOM663CD2TRPA 906.507 23.396-6.0001.00 7.96C
ATOM664CE3 TRPA 907.505 22.419-5.8041.00 7.84C
ATOM665CZ3TRPA 907.661 21.426-6.7601.00 8.94C
ATOM666CH2TRPA 906.847 21.381-7.8991.00 9.47C
ATOM667CZ2TRPA 905.864 22.311-8.1131.00 8.43C
ATOM668C TRPA 904.819 24.995-2.2991.00 7.64C
ATOM669O TRPA 905.151 24.325-1.3191.00 7.71O
ATOM670N LEUA 913.585 25.000-2.8001.00 8.34N
ATOM671CA LEUA 912.521 24.186-2.228 1.00 8.60C
ATOM672CB LEUA 911.800 24.991-1.160 1.00 8.11C
ATOM673CG LEUA 910.763 24.226-0.324 1.00 9.82C
ATOM674CDl LEUA 911.370 23.0230.4171.0012.77C
ATOM675CD2LEUA 910.066 25.1880.6301.0012.11C
ATOM676C LEUA 911.562 23.779-3.3421.00 9.49C
ATOM677O LEUA 911.033 24.646-4.0351.00 9.62O
ATOM678N VALA 921.359 22.470-3.5011.00 9.41N
ATOM679CA VALA 920.487 21.941-4.538 1.0010.23C
ATOM680CB VALA 921.298 21.302-5.677 1.00 9.84C
ATOM681CGl VALA 920.403 20.846-6.8311.0010.65C
ATOM682CG2VALA 922.385 22.268-6.2091.0010.59C
[0581]ATOM683C VALA 92 -0.385 20.864 -3.907 1.00 10.75CATOM684O VALA 92 0.100 20.023 -3.132 1.00 11.18O
ATOM685N THRA 93 -1.667 20.857 -4.251 1.0010.91N
ATOM686CA THRA 93 -2.595 19.882 -3.655 1.0011.96 C
ATOM687CB THRA 93 -3.603 20.559 -2.727 1.0012.12 C
ATOM688OGl THRA 93 -4.412 21.493 -3.482 1.00 14.35O
ATOM689CG2THRA 93 -2.862 21.282 -1.592 1.00 14.25C
ATOM690C THRA 93 -3.338 19.117 -4.742 1.00 11.26C·ATOM691O THRA 93 -3.227 19.450 -5.904 1.0011.58O
ATOM692N ASPA 94 -4.101 18.099 -4.338 1.0011.43N
ATOM693CA ASPA 94 -4.919 17.313 -5.280 1.0011.92C
ATOM694CB ASPA 94 -6.093 18.151 -5.837 1.0012.03C
ATOM695CG ASPA 94 -7.249 18.318 -4.857 1.0013.96C
ATOM696ODl ASPA 94 -7.226 17.802 -3.717 1.0012.99O
ATOM697OD2ASPA 94 -8.202 19.019 -5.264 1.0019.42O
ATOM698C ASPA 94 -4.078 16.789 -6.442 1.0011.54C
ATOM699O ASPA 94 -4.545 16.758 -7.599 1.0012.67O
ATOM700N ILEA 95 -2.847 16.350 -6.158 1.0011.13N
ATOM701CA ILEA 95 -2.035 15.704 -7.184 1.0010.88C
ATOM702CB ILEA 95 -0.543 15.699 -6.806 1.0010.33C
ATOM703CGl ILEA 95 -0.030 17.136 -6.564 1.00 10.03C
ATOM704CDl ILEA 95 1.299 17.205 -5.814 1.0010.35C
ATOM705CG2ILEA 95 0.257 14.960 -7.877 1.0011.90C
ATOM706C ILEA 95 -2.483 14.249 -7.369 1.00 10.78C
ATOM707O ILEA 95 -2.428 13.475 -6.415 1.0011.23O
ATOM708N PROA 96 -2.936 13.878 -8.586 1.0011.11N
ATOM709CA PROA 96 -3.361 12.480 -8.740 1.00 11.36C
ATOM710CB PROA 96 -3.968 12.456-10.147 1.0011.86C
ATOM711CG PROA 96 -4.285 13.873 -10.467 1.0011.17C
ATOM712CD PROA 96 -3.130 14.631 -9.832 1.00 10.94C
ATOM713C PROA 96 -2.208 11.495 -8.667 1.0011.30C
ATOM714O PROA 96 -1.126 11.722 -9.242 1.0011.03O
ATOM715N GLYA 97 -2.456 10.375 -7.996 1.0011.13N
ATOM716CA GLYA 97 -1.457 9.323 -7.898 1.00 12.00C
ATOM717C GLYA 97 -1.037 8.875 -9.279 1.0011.98C
ATOM718O GLYA 97 -1.829 8.921 -10.232 1.00 11.74O
ATOM719N THRA 98 0.220 8.452 -9.374 1.0013.09N
ATOM720CA THRA 98 0.869 8.009-10.626 1.0013.70C
ATOM721CB THRA 98 0.148 6.814-11.366 1.0013.74C
ATOM722OGl THRA 98 -1.010 7.283 -12.081 1.0015.52O
ATOM723CG2THRA 98 -0.243 5.728 -10.394 1.0014.60C
ATOM724C THRA 98 1.139 9.149-11.604 1.0014.27C
ATOM725O THRA 98 1.608 8.908 -12.708 1.0015.60O
ATOM726N THRA 99 0.832 10.389-11.217 1.0013.18N
[0582]ATOM727CA THRA 99 1.107 11.527-12.102 1.0012.89 CATOM728CB THRA 99 -0.176 12.335-12.512 1.00 13.67 C
ATOM729 OGl THRA 99 -0.656 13.144-11.429 1.0012.87 O
ATOM730CG2THRA 99 -1.284 11.407-13.040 1.0014.02C
ATOM731C THRA 992.249 12.425-11.582 1.0012.99C
ATOM732O THRA 99 3.327 11.931 -11.280 1.0013.12 O
ATOM733N ALAA1002.033 13.734-11.529 1.0012.68N
ATOM734CA ALAA1003.090 14.657-11.117 1.0011.77C
ATOM735CB ALAA1004.032 14.965 -12.298 1.0012.20C
ATOM736C ALAA1002.481 15.936-10.575 1.0011.63C
ATOM737O ALAA1001.296 16.215-10.811 1.00 10.64O
ATOM738N ALAA1013.294 16.743 -9.889 1.0011.30N
ATOM739CA ALAA1012.793 17.975 -9.291 1.00 11.18 C
ATOM740CB ALAA1013.906 18.698 -8.518 1.0010.54 C
ATOM741C ALAA1012.143 18.922-10.312 1.0012.00C
ATOM742O ALAA1011.199 19.644 -9.981 1.0012.35O
ATOM743N SERA 1022.627 18.884-11.557 1.0013.14N
ATOM744CA SERA 1022.049 19.712-12.629 1.0014.55C
ATOM745CB SERA 1022.923 19.651 -13.887 1.0015.27C
ATOM746OG SERA 1023.029 18.337-14.373 1.0017.69O
ATOM747C SERA 1020.581 19.383 -12.956 1.0014.98C
ATOM748O SERA 102-0.114 20.176-13.603 1.0014.30O
ATOM749N PHEA1030.106 18.229-12.488 1.0014.28N
ATOM750CA PHEA103-1.297 17.822-12.675 1.00 13.69C
ATOM751CB PHEA103-1.379 16.327-13.009 1.0014.54C
ATOM752CG PHEA103-0.736 15.968-14.313 1.00 15.30C
ATOM753CDl PHEA1030.587 15.568-14.366 1.0017.34C
ATOM754CEl PHEA1031.177 15.218-15.581 1.0019.81C
ATOM755CZ PHEA1030.435 15.284-16.763 1.0019.20C
ATOM756CE2PHEA103-0.885 15.708-16.724 1.0021.07C
ATOM757CD2 PHEA103-1.469 16.031 -15.498 1.0019.05C
ATOM758C PHEA103-2.197 18.144-11.473 1.0013.77C
ATOM759O PHEA103-3.398 17.874-11.487 1.0014.00O
ATOM760N GLYA104-1.603 18.716-10.428 1.0012.89N
ATOM761CA GLYA104-2.345 19.118 -9.239 1.0013.71C
ATOM762C GLYA104-2.793 20.576 -9.280 1.00 13.46C
ATOM763O GLYA104-2.705 21.253-10.309 1.0014.84O
ATOM764N GLNA105-3.278 21.045 -8.140 1.0013.60N
ATOM765CA GLN A105-3.740 22.417 -7.952 1.0013.67 C
ATOM766CB GLNA105-5.004 22.420 -7.067 1.0015.08 C
ATOM767CG GLNA105-5.539 23.801 -6.654 1.0018.75 C
ATOM768CD GLNA105-6.079 24.610 -7.822 1.0024.42 C
ATOM769OEl GLNA105-6.881 24.113 -8.613 1.0025.27O
ATOM770NE2 GLNA105-5.640 25.861 -7.935 1.00 24.80N
[0583]ATOM 771C GLNA105 -2.636 23.226-7.2851.0013.40CATOM 772O GLNA105 -2.291 22.951-6.1401.0013.14O
ATOM 773N GLUA106 -2.086 24.208-7.9941.0013.06N
ATOM 774CA GLUA106 -1.093 25.088 -7.403 1.00 12.71 C
ATOM775CB GLU A106 -0.409 25.936-8.474 1.0012.64 C
ATOM776CG GLU A106 0.675 26.837 -7.918 1.0014.18 C
ATOM777CD GLUA106 1.356 27.621 -9.005 1.00 14.34 C ATOM778OEl GLUA106 2.180 27.034-9.7311.0015.78O
ATOM779OE2 GLUA106 1.051 28.831-9.1451.0017.06O
ATOM780C GLU A106 -1.762 25.959-6.3561.00 12.69C
ATOM781O GLUA106 -2.740 26.650-6.6421.0013.76O
ATOM782N VALA107 -1.274 25.876-5.1271.0011.35N
ATOM783CA VALA107 -1.785 26.718-4.0351.0011.75C
ATOM784CB VALA107 -2.046 25.870-2.7831.0011.64C
ATOM785CGl VALA107 -2.493 26.751-1.6061.00 12.09C
ATOM786CG2 VALA107 -3.099 24.796-3.0901.00 13.27C
ATOM787C VALA107 -0.845 27.901-3.7721.00 11.57C
ATOM788O VALA107 -1.287 29.035-3.5741.0012.74O
ATOM789N META 108 0.460 27.635-3.7711.0010.59N
ATOM790CA META 108 1.477 28.679 -3.647 1.0010.72 C
ATOM791CB META 108 2.168 28.601-2.283 1.0010.85 C
ATOM792CG META 108 1.242 28.882 -1.122 1.0011.87 C
ATOM793SD META 108 0.513 30.546-1.1291.0014.91 S
ATOM794CE META 108 1.796 31.455-0.2771.0015.90 C
ATOM795C META 108 2.492 28.419-4.7401.00 10.62C
ATOM796O META 108 3.038 27.321-4.8161.0010.42O
ATOM797N SER A109 2.737 29.400-5.5981.00 10.17N
ATOM798CA SERA 109 3.697 29.261-6.6961.0010.51C
ATOM799CB SERA 109 3.684 30.517-7.5671.0010.85C
ATOM800OG SERA 109 4.113 31.646-6.8181.0013.34O
ATOM801C SERA 109 5.113 29.005-6.1821.0010.03C
ATOM802O SERA 109 5.473 29.392-5.0721.00 9.10O
ATOM803N TYRA110 5.930 28.358-7.0001.00 9.66N
ATOM804CA TYRA110 7.311 28.074-6.6681.00 9.56 C
ATOM805CB TYRA110 7.888 27.131-7.7171.00 9.06 C
ATOM806CG TYRA110 9.304 26.656-7.4881.00 8.90 C
ATOM807CDl TYRA110 10.387 27.334-8.0501.00 9.27 C
ATOM808CEl TYRA110 11.692 26.870-7.8631.00 8.98C
ATOM809CZ TYRA110 11.938 25.739-7.1061.00 8.80 C
ATOM810OH TYRA110 13.212 25.238 -6.923 1.00 9.40 O
ATOM811CE2TYRA110 10.869 25.058-6.5321.00 9.65C
ATOM812CD2TYRA110 9.567 25.515-6.7381.00 8.74 C
ATOM813C TYRA110 8.144 29.345-6.6241.0010.02C
ATOM814O TYRA110 8.211 30.087-7.6291.00 11.20O
[0584]ATOM815N GLUA 1118.79029.562 -5.4821.0010.05NATOM816CA GLUA 1119.75730.652 -5.3231.0010.15C
ATOM817CB GLUA 1119.55631.362 -3.9791.0010.04C
ATOM818CG GLUA 11110.54632.507 -3.7201.0012.39C
ATOM819CD GLUA 11110.30033.234 -2.4111.0012.58C
ATOM820OEl GLUA1119.12933.313 -1.9611.0014.03O
ATOM821OE2 GLUA 11111.30233.717 -1.8501.0014.81O·
ATOM822C GLUA 11111.16830.071 -5.3801.0010.67C·ATOM823O GLUA 11111.47229.109 -4.6761.0010.99O
ATOM824N SERA 11212.05130.664 -6.1991.00 11.47N
ATOM825CA SERA 11213.43430.181 -6.3281.0012.27C
ATOM826CB SERA 11214.21631.078 -7.293LOO 12.98C
ATOM827OG SERA 11213.54331.240 -8.5181.0014.60O
ATOM828C SERA 11214.20830.149 -5.0111.0012.28C
ATOM829O SERA 11214.29331.172 -4.3261.00 13.14O
ATOM830N PROA 11314.80729.005 -4.6401.0012.08N
ATOM831CA PROA 11315.74729.046 -3.5151.0012.12C
ATOM832CB PROA 11316.19427.587 -3.3691.0012.00C
ATOM833CG PROA 11315.05626.791 -3.9671.0011.86C
ATOM834CD PROA 11314.59727.623 -5.1211.0011.81C
ATOM835C PROA 11316.96029.931 -3.7981.0013.02C
ATOM836O PROA 11317.62429.776 -4.8351.0012.77O
ATOM837N ARGA11417.26430.832 -2.8641.0012.67N
ATOM838CA ARGA11418.44231.712 -2.9691.0014.34C
ATOM839CB ARGA11417.99933.128 -3.3181.0015.11C
ATOM840CG ARGA11417.26033.237 -4.6561.0018.32C
ATOM841CD ARGA11416.89334.673 -4.9691.0026.56C
ATOM842NE ARGA11416.15235.293 -3.8781.0031.69N
ATOM843CZ ARGA11414.82935.258 -3.7441.00 33.27C
ATOM844NHl ARGA11414.07234.625 -4.6341.00 35.42N
ATOM845NH2 ARGA11414.26235.855 -2.7101.00 34.90N
ATOM846C ARGA11419.23331.670 -1.6511.0013.74C
ATOM847O ARGA11419.26932.650 -0.9041.0014.22O
ATOM848N PRO A11519.86630.526 -1.3441.0013.88N
ATOM849CA PROA 11520.50730.380 -0.0331.0013.86C
ATOM850CB PROA 11520.97428.917 -0.0351.0014.45C
ATOM851CG PROA 11521.14628.598 -1.4891.0014.04C
ATOM852CD PROA 11520.03429.326 -2.1751.0013.73C
ATOM853C PROA 11521.71831.300 0.1261.0014.67C
ATOM854O PROA 11522.48631.487 -0.8221.0015.81O
ATOM855N THRA11621.84631.890 1.3061.0014.57N
ATOM856CA THRA11623.07532.568 1.7271.0015.62C
ATOM857CB THRA11622.99234.107 1.6131.0015.85C
ATOM858OGl THRA11622.15934.617 2.6591.0016.51O
[0585]ATOM903N LEUA12216.54422.321 1.3491.0011.10N
ATOM904CA LEUA12215.26622.541 0.657 1.0010.59C
ATOM905CB LEUA12215.49123.018-0.7731.0011.01C
ATOM906CG LEU A12215.93324.482 -0.935 1.00 9.29 C
ATOM907CDl LEUA12214.97725.433-0.1761.0011.83C
ATOM908CD2LEUA12217.41124.736-0.5251.00 12.76C
ATOM909C LEUA12214.51421.226 0.6921.0010.81C
ATOM910O LEUA12214.96320.224 0.1241.0010.75O·ATOM911N VALA12313.40021.223 1.4081.00 9.83N
ATOM912CA VALA12312.73720.010 1.845 1.00 9.54 C
ATOM913CB VALA12312.49420.036 3.3951.00 9.97 C
ATOM914CGl VALA12311.77618.785 3.8691.0011.17C
ATOM915CG2VALA12313.81520.228 4.1821.0010.12C
ATOM916C VALA12311.40019.859 1.1311.00 9.63C
ATOM917O VALA12310.57320.765 1.1801.00 9.57O
ATOM918N PHEA12411.19718.705 0.4921.00 9.73N
ATOM919CA PHEA1249.91818.347-0.1451.00 9.69C
ATOM920CB PHEA12410.14117.764-1.5361.00 9.63C
ATOM921CG PHEA12410.84718.685-2.4621.00 7.46C
ATOM922CDl PHEA12412.24218.839-2.4161.00 8.40C
ATOM923CEl PHEA12412.86219.728-3.2921.0010.48C
ATOM924CZ PHEA12412.10220.466-4.1861.00 8.85C
ATOM925CE2 PHEA12410.74120.321-4.2201.00 8.33C
ATOM926CD2PHEA12410.11619.455-3.3621.00 8.77C
ATOM927C PHEA1249.23617.3120.7041.0010.45C
ATOM928O PHEA1249.88716.331 1.0861.0011.33O
ATOM929N VALA1257.95617.5091.0071.00 9.83N
ATOM930CA VALA1257.19116.596 1.8631.0010.12C
ATOM931CB VALA1256.82817.207 3.2421.0010.33C
ATOM932CGl VALA1256.26416.1234.1811.00 10.69C
ATOM933CG2VALA1258.03317.9123.8911.00 11.21C
ATOM934C VALA1255.90916.2451.1191.0011.31C
ATOM935O VALA1255.20017.1380.6291.0010.47O
ATOM936N LEUA1265.62214.946 1.0171.0011.31N
ATOM937CA LEUA1264.42914.477 0.3171.0013.02C
ATOM938CB LEUA1264.81113.458-0.7601.0013.12C
ATOM939CG LEUA1263.73413.135-1.7971.0013.99C
ATOM940CDl LEUA1263.46214.325-2.7251.0011.96C
ATOM941CD2 LEUA1264.12411.908-2.6181.00 13.59C
ATOM942C LEUA1263.47513.863 1.3151.0012.82C
ATOM943O LEUA1263.89313.0332.1281.0012.99O
ATOM944N PHEA1272.22014.2891.2741.0012.69N
ATOM945CA PHEA1271.15313.702 2.0891.0013.21C
ATOM946CB PHEA1270.47814.770 2.9431.00 13.79C
[0587]ATOM947 CG PHEA127 1.395 15.4213.934 1.0014.67CATOM948CDl PHEA127 1.573 14.8635.1971.0016.53C
ATOM949CEl PHEA127 2.420 15.4526.1321.0015.30C
ATOM950CZ PHEA127 3.109 16.6215.8001.0014.76C
ATOM951CE2 PHEA127 2.933 17.1904.5331.0015.46C
ATOM952CD2 PHE A127 2.074 16.5953.6101.00 14.89C
ATOM953C PHEA127 0.115 13.0791.1911.0013.58C
ATOM954O PHEA127 -0.165 13.5710.0981.0012.54O
ATOM955N GLNA128 -0.475 11.9981.6771.0014.07N
ATOM956CA GLNA128 -1.628 11.4011.039 1.0015.00C
ATOM957CB GLNA128 -1.593 9.8921.263 1.0014.40C
ATOM958CG GLNA128 -2.647 9.1190.498 1.0017.88C
ATOM959CD GLNA128 -2.471 7.6200.655 1.0019.02C
ATOM960OEl GLNA128 -1.358 7.0990.5561.0023.21O
ATOM961NE2 GLNA128 -3.568 6.9170.8961.00 22.83N
ATOM962C GLNA128 -2.898 11.9841.6471.0014.63C
ATOM963O GLNA128 -3.084 11.9612.8681.00 16.63O
ATOM964N GLNA129 -3.763 12.5250.7971.00 15.09N
ATOM965CA GLNA129 -5.054 13.0671.206 1.0014.67C
ATOM966CB GLNA129 -5.546 14.0500.154 1.0015.37C
ATOM967CG GLNA129 -4.582 15.224-0.057 1.0013.79C
ATOM968CD GLN A129 -4.934 16.116-1.2471.00 13.40C
ATOM969OEl GLNA129 -4.049 16.816-1.7691.0013.01O
ATOM970NE2 GLNA129 -6.204 16.101-1.6981.0011.64N
ATOM971C GLNA129 -6.083 11.9441.3701.0016.55C
ATOM972O GLNA129 -5.941 10.8730.7661.00 16.37O
ATOM973N LEUA130 -7.109 12.1892.1831.0018.50N
ATOM974CA LEUA130 -8.207 11.2072.2871.0019.97C
ATOM975CB LEUA130 -9.097 11.4633.5171.0019.90C
ATOM976CG LEUA130 -8.622 10.8834.8581.00 22.65C
ATOM977CDl LEUA130 -9.673 11.0885.9471.0023.26C
ATOM978CD2 LEUA130 -8.245 9.4004.7771.0024.56C
ATOM979C LEUA130 -9.055 11.1821.0221.00 20.25C
ATOM980O LEUA130 -9.735 10.1960.7491.0020.92O
ATOM981N GLYA131 -9.024 12.2840.2771.0020.14N
ATOM982CA GLYA131 -9.701 12.458-1.0151.0019.37C
ATOM983C GLYA131 -9.372 13.880-1.4831.0019.58C
ATOM984O GLYA131 -8.575 14.563-0.8411.0018.85O
ATOM985N ARGA132 -9.980 14.334-2.5801.0019.45N
ATOM986CA ARGA132 -9.835 15.728 -3.012 1.0020.28C
ATOM987CB ARGA132-10.724 16.049-4.2141.0020.91C
ATOM988CG ARGA132-10.174 15.577-5.5431.0023.26C
ATOM989CD ARGA132-10.734 16.402-6.6881.0027.64C
ATOM990NE ARGA132-10.051 16.107-7.9461.00 30.86N
[0588]ATOM1035O ALAA137 -3.762 30.9482.148 1.0012.38O
ATOM1036N PROA 138 -1.873 29.7342.294 1.0012.25N
ATOM1037CA PROA 138 -1.389 30.4793.445 1.0012.45 C
ATOM1038CB PROA 138 0.023 29.9053.642 1.0012.65 C
ATOM1039CG PROA 138 -0.158 28.4753. 235 1.0012.72 C
ATOM1040CD PROA 138 -0.994 28.5821.993 1.0012.44 C
Α1ΌΜ1041C PROA 138 -1.331 31.9643.132 1.00 12.13C
ATOM1042O PROA 138 -1.088 32.3351.981 1.0013.03O
ATOM1043N GLYA139 -1.599 32.7964.136 1.0012.36N
ATOM1044CA GLYA139 -1.580 34.2413.947 1.0012.46 C
ATOM1045C GLYA139 -0.193 34.8403.792 1.0012.60C
ATOM1046O GLYA139 -0.050 35.9873.403 1.0013.35O
ATOM1047N TRPA140 0.839 34.0534.104 1.0012.05N
ATOM1048CA TRPA140 2.243 34.4824.004 1.0011.38C
ATOM1049CB TRPA140 2.613 35.4365.159 1.00 11.60C
ATOM1050CG TRPA140 2.293 34.8566.509 1.0012.07C
ATOM1051CDl TRPA140 3.077 34.0027.246 1.0011.39C
ATOM1052NEl TRPA140 2.441 33.6508.402 1.0012.72N
ATOM1053CE2 TRPA140 1.213 34.2568.446 1.0011.61C
ATOM1054CD2 TRPA140 1.077 35.0157.255 1.0010.56C
ATOM1055CE3 TRPA140 -0.099 35.7537.054 1.0012.34C
ATOM1056CZ3 TRPA140 -1.090 35.7048.021 1.0012.25C
ATOM1057CH2 TRPA140 -0.932 34.9299.196 1.0012.88C
ATOM1058CZ2 TRPA140 0.214 34.2079.429 1.0012.38C
ATOM1059C TRPA140 3.102 33.2224.023 1.0010.15C
ATOM1060O TRPA140 2.653 32.1604.460 1.0010.45O
ATOM1061N ARGA141 4.327 33.3473.542 1.00 9.66 N
ATOM1062CA ARGA141 5.212 32.198 3.400 1.00 8.72 C
ATOM1063CB ARGA141 6.017 32.3352.110 1.00 8.68 C
ATOM1064CG ARGA141 5.188 32.246 0.838 1.00 9.36 C
ATOM1065CD ARGA141 6.057 32.535-0.355 1.0011.08 C
ATOM1066NE ARGA141 5.326 32.504-1.622 1.0010.70 N
ATOM1067CZ ARGA141 5.378 31.523-2.526 1.00 9.22 C
ATOM1068NHl ARGA141 6.131 30.443-2.325 1.00 9.69 N
ATOM1069NH2ARGA141 4.687 31.634-3.650 1.0010.33N
ATOM1070C ARGA141 6.144 31.9564.586 1.00 8.52 C
ATOM1071O ARGA141 6.623 30.8304.794 1.00 8.51 O
ATOM1072N GLNA142 6.446 32.9875.352 1.00 8.87 N
ATOM1073CA GLNA142 7.421 32.8236.422 1.00 9.56 C
ATOM1074CB GLNA142 8.093 34.1526.782 1.0011.20 C
ATOM1075CG GLNA142 7.277 35.053 7.669 1.0013.08 C
ATOM1076CD GLNA142 6.243 35.866 6.947 1.0012.46 C
ATOM1077OEl GLNA142 6.078 35.7945.716 1.0013.85O
ATOM1078NE2 GLNA142 5.531 36.6807.724 1.0016.54N
[0590]ATOM1079C GLNA1426.800 32.1597.6501.00 9.75CATOM1080O GLNA1425.578 32.2427.8751.00 9.56O
ATOM1081N ASNA1437.634 31.4898.4391.00 9.63N
ATOM1082CA ASNA143 7.174 30.8759.6891.00 9.86 C
ATOM1083CB ASNA1436.876 31.96410.7491.0010.64C
ATOM1084CG ASNA143 8.100 32.79611.0861.0011.63C
ATOM1085ODl ASNA1438.095 34.00210.9101.00 15.35O
ATOM1086ND2ASNA1439.169 32.14311.5371.0012.42N
ATOM1087C ASNA1435.983 29.9369.4761.0010.55C
ATOM1088O ASNA1435.035 29.88110.2761.00 11.27O
ATOM1089N PHEA1446.034 29.2318.3481.00 9.68N
ATOM1090CA PHEA1445.137 28.1038.0761.00 8.73C
ATOM1091CB PHEA1445.272 27.7136.5951.00 9.14C
ATOM1092CG PHEA1444.309 26.6486.1141.00 8.97C
ATOM1093CDl PHEA1443.004 26.9735.7701.00 8.19C
ATOM1094CEl PHEA1442.126 25.9745.2961.00 9.14C
ATOM1095CZ PHEA1442.587 24.6785.1391.00 9.36C
ATOM1096CE2 PHEA1443.900 24.3595.4721.00 8.56C
ATOM1097CD2 PHEA1444.737 25.3305.9641.00 9.09C
ATOM1098C PHEA1445.506 26.9328.9941.00 9.05C
ATOM1099O PHEA1446.645 26.8239.4741.00 9.38O
ATOM1100N ASNA1454.535 26.0599.2471.00 9.65N
ATOM1101CA ASNA1454.789 24.88310.0641.00 10.23C
ATOM1102CB ASNA1454.346 25.09611.5151.00 10.90C
ATOM1103CG ASNA1454.847 24.01212.4091.0012.57C
ATOM1104ODl ASNA1454.290 22.91512.4401.0012.21O
ATOM1105ND2ASNA1455.936 24.28413.1151.0014.68N
ATOM1106C ASNA1454.102 23.6859.4591.0010.44C
ATOM1107O ASNA1452.880 23.5669.5161.0010.47O
ATOM1108N THRA1464.905 22.7978.8811.00 9.97N
ATOM1109CA THRA1464.387 21.6428.1481.00 10.67C
ATOM1110CB THRA1465.530 20.8717.4811.0010.45C
ATOM1111OGl THRA1466.124 21.7166.4931.00 10.30O
ATOM1112CG2 THRA1465.028 19.6266.7611.0010.92C
ATOM1113C THRA1463.551 20.7379.0431.0011.55C
ATOM1114O THRA1462.496 20.2498.6111.0012.15O
ATOM1115N LYSA1473.993 20.56010.2881.0012.41N
ATOM1116CA LYSA1473.218 19.75211.2541.0013.55C
ATOM1117CB LYSA1473.987 19.57512.5501.0014.23C
ATOM1118CG LYSA1475.138 18.61612.4731.0017.93C
ATOM1119CD LYSA1475.862 18.59013.8101.0021.51C
ATOM1120CE LYSA1477.079 17.70713.7601.0023.93C
ATOM1121NZ LYSA1477.807 17.73915.0661.0026.40N
ATOM1122C LYSA1471.860 20.38611.5341.0013.72C[0591]ATOM1123O LYSA1470.83219.70511.5121.0014.53O
ATOM1124N ASPA1481.82321.68711.7861.0013.45N
ATOM1125CA ASPA1480.54722.36912.0301.0013.94C
ATOM1126CB ASPA1480.76323.83212.4061.00 14.55C
ATOM1127CG ASPA1481.46924.00013.7481.0015.94C
ATOM1128ODl ASPA1481.53923.01414.5271.0018.07O
ATOM1129OD2ASPA1481.96425.12913.9821.0019.43O
ATOM1130C ASPA148-0.35622.29810.8001.0014.52C
ATOM1131O ASPA148-1.56922.12410.9201.0015.55O
ATOM1132N PHEA1490.23922.4559.6151.0013.72N
ATOM1133CA PHEA149-0.48422.4278.3501.0013.57C
ATOM1134CB PHEA1490.49922.7517.2171.0012.47C
ATOM1135CG PHEA149-0.05522.5615.8321.0011.03C
ATOM1136CDl PHE A149-0.87123.5195.2781.0011.99C
ATOM1137CEl PHEA149-1.37423.3613.9861.0011.02C
ATOM1138CZ PHEA149-1.05822.2213.2581.00 11.51C
ATOM1139CE2 PHEA149-0.24421.2663.8021.0012.90C
ATOM1140CD2PHEA1490.26121.4315.0861.0012.02C
ATOM1141C PHEA149-1.14921.0648.1381.0014.01C
ATOM1142O PHEA149-2.32220.9987.7791.0013.74O
ATOM1143N ALAA150-0.39719.9908.3591.0015.01N
ATOM1144CA ALAA150 -0.91918.6298.1731.0015.77C
ATOM1145CB ALAA1500.17317.6098.2851.00 15.18C
ATOM1146C ALAA150-2.04018.3439.1651.0016.79C
ATOM1147O ALAA150-3.00417.6428.8351.0017.16O
ATOM1148N GLUA151-1.91918.89710.3671.0017.48N
ATOM1149CA GLUA151 -2.934 18.77811.4001.0018.12C
ATOM1150CB GLUA151-2.41719.37212.7141.0018.66C
ATOM1151CG GLUA151-3.394 19.30013.882 1.0019.71C
ATOM1152CD GLUA151 -3.72317.87614.291 1.00 22.61C
ATOM1153OEl GLUA151-2.79317.05614.4251.0025.66O
ATOM1154OE2 GLUA151-4.92317.58814.4791.00 23.68O
ATOM1155C GLUA151-4.21619.45810.9511.0018.07C
ATOM1156O GLUA151-5.28018.82910.9831.00 18.28O
ATOM1157N LEUA152-4.11220.71610.5061.0017.59N
ATOM1158CA LEU A152-5.23821.50810.0081.0017.94C
ATOM1159CB LEU A152-4.76622.8879.5081.0017.76C
ATOM1160CG LEUA152-5.80723.9779.1921.0018.37C
ATOM1161CDl LEUA152-6.68524.30810.4201.0021.33C
ATOM1162CD2 LEUA152-5.14625.2378.6671.0018.72C
ATOM1163C LEUA152-6.01420.7618.9221.0017.06C
ATOM1164O LEUA152-7.25120.6918.9721.0018.52O
ATOM1165N TYRA153-5.29420.1497.9851.0016.96N
ATOM1166CA TYRA153-5.92419.5496.8091.0016.72C
[0592]ATOM1167CB TYRA153-5.21020.0345.5481.0016.28CATOM1168CG TYRA153-5.46321.496 5.309 1.0014.51C
ATOM1169CDl TYRA153-6.72221.9424.9061.0013.96C
ATOM1170CEl TYR A153-6.98823.2924.6921.0014.15C
ATOM1171CZ TYRA153-5.98724.2384.8871.0014.55C
ATOM1172OH TYRA153 -6.263 25.579 4.657 1.0015.55O
ATOM1173CE2 TYRA153-4.72223.8235.2991.0014.25C ATOM1174CD2 TYRA153-4.46322.4515.5091.00 13.74C
ATOM1175C TYRA153-6.05418.0196.8361.00 17.52C
ATOM1176O TYRA153-6.39817.4025.8231.00 17.05O
ATOM1177N ASNA154-5.79317.4208.0011.00 18.63N
ATOM1178CA ASNA154-5.82415.953 8.1671.00 18.72C
ATOM1179CB ASN A154-7.27015.4368.2781.0019.28C
ATOM1180CG ASNA154-7.34113.994 8.7421.0021.31C
ATOM1181ODl ASNA154-6.43513.4969.4121.00 21.09O
ATOM1182ND2ASNA154-8.41613.3078.3671.00 23.10N
ATOM1183C ASN A154-5.05015.2017.0811.0019.12C
ATOM1184O ASNA154-5.57414.3076.4041.0019.41O
ATOM1185N LEUA155-3.79015.5706.9261.0018.73N
ATOM1186CA LEUA155-2.93314.9495.9391.0019.64C
ATOM1187CB LEUA155-1.99016.0015.3551.00 19.37C
ATOM1188CG LEUA155-2.72017.1144.5981.00 19.63C
ATOM1189CDl LEUA155-1.73518.1554.1511.0017.67C
ATOM1190CD2 LEUA155-3.47016.5503.3981.0019.42C
ATOM1191C LEUA155-2.15513.7776.5171.0019.88C
ATOM1192O LEUA155-1.41413.1115.7911.0020.91O
ATOM1193N GLYA156-2.32513.5417.8201.0020.53N
ATOM1194CA GLYA156-1.63712.4588.5321.0020.50C
ATOM1195C GLYA156-0.14112.6718.6031.0020.23C
ATOM1196O GLYA1560.31813.8128.6971.0021.15O
ATOM1197N SERA 1570.62311.5818.5601.0019.83N
ATOM1198CA SERA 1572.08311.6498.5071.0019.53C
ATOM1199CB SERA 1572.71010.5109.3251.0019.37C
ATOM1200OG SERA 1572.1709.2528.9501.0021.33O
ATOM1201C SERA 1572.56411.5827.0601.0018.45C
ATOM1202O SERA 1571.86611.0306.1961.00 18.67O
ATOM1203N PROA 1583.75212.1436.7701.0017.29N
ATOM1204CA PROA 1584.26812.102 5.3981.0016.75C
ATOM1205CB PROA 1585.69912.6105.5461.0016.44C
ATOM1206CG PROA 1585.66513.478 6.758 1.0016.01C
ATOM1207CD PROA 1584.64712.8857.6801.00 17.00C
ATOM1208C PROA 1584.28910.6864.8111.0016.87C
ATOM1209O PROA 1584.5339.7035.5371.0017.66O
ATOM1210N VALA1594.00710.5743.5211.0016.32N
[0593]ATOM1211CA VALA1594.2199.3172.812 1.0015.92CATOM1212CB VALA1593.0979.0191.808 1.0016.62C
ATOM1213CGl VALA1591.7908.8232.538 1.0016.77C
ATOM1214CG2VALA1592.99610.1170.717 1.0014.85C
ATOM1215C VALA1595.5899.2662.144 1.0015.38C
ATOM1216O VALA1596.0688.1971.762 1.0015.63O
ATOM1217N ALAA1606.22910.4352.016 1.00 13.87N
ATOM1218CA ALAA1607.54310.5471.428 1.0013.29C
ATOM1219CB ALAA1607.47910.356-0.079 1.0014.31C
ATOM1220C ALAA1608.12911.9131.746 1.00 13.11C
ATOM1221O ALAA1607.39612.8731.971 1.00 13.88O
ATOM1222N ALAA1619.44711.9821.737 1.0013.56N
ATOM1223CA ALAA16110.127 13.2681.794 1.0014.00C
ATOM1224CB ALAA16110.12013.8543.224 1.0013.91C
ATOM1225C ALAA16111.53813.1521.266 1.0014.79C
ATOM1226O ALAA16112.14512.0781.330 1.0015.53O
ATOM1227N VAL A16212.07214.2470.749 1.0014.96N
ATOM1228CA VALA16213.43314.2730.254 1.0014.10C
ATOM1229CB VALA16213.53313.713-1.190 1.0014.46C
ATOM1230CGl VALA16213.04114.726-2.200 1.0013.96C
ATOM1231CG2 VALA16214.94713.206-1.535 1.0014.31C
ATOM1232C VALA16213.91615.6990.392 1.0014.11C
ATOM1233O VALA16213.11416.6380.417 1.0012.90O
ATOM1234N TYRA16315.21115.8860.541 1.0014.12N
ATOM1235CA TYRA16315.73117.2310.567 1.0014.32C
ATOM1236CB TYRA16315.93417.7272.009 1.0014.45C
ATOM1237CG TYRA16317.15217.1442.711 1.0014.76C
ATOM1238CDl TYRA16318.32617.8692.817 1.0015.77C
ATOM1239CEl TYRA16319.46017.3123.456 1.0014.86C
ATOM1240CZ TYRA16319.37916.0473.987 1.0015.49C
ATOM1241OH TYRA16320.477 15.4774.620 1.0017.60O
ATOM1242CE2 TYRA16318.21815.3193.892 1.0015.78C
ATOM1243CD2 TYRA16317.11315.8653.259 1.0015.86C
ATOM1244C TYRA16317.02817.310-0.192 1.0014.67C
ATOM1245O TYRA16317.75616.317-0.287 1.0015.31O
ATOM1246N PHEA16417.31918.481-0.720 1.0014.09N
ATOM1247CA PHEA16418.65118.772-1.196 1.0013.71C
ATOM1248CB PHEA16418.67519.063-2.703 1.0013.88C
ATOM1249CG PHEA16417.96620.310-3.124 1.0013.15C
ATOM1250CDl PHEA16416.63720.267-3.521 1.0012.93C
ATOM1251CEl PHEA16415.99521.427-3.968 1.0010.81C
ATOM1252CZ PHEA16416.68622.628-4.039 1.0012.04C
ATOM1253CE2 PHEA16418.02922.674-3.634 1.0012.05C
ATOM1254CD2PHEA16418.65321.518-3.211 1.0012.96C
[0594]ATOM1255C PHEA16419.289 19.863-0.3581.0014.36CATOM1256O PHEA16418.598 20.6130.3461.0013.83O
ATOM1257N ASNA16520.612 19.920-0.3951.0015.33N
ATOM1258CA ASNA16521.339 21.024 0.1931.0016.05C
ATOM1259CB ASNA16522.604 20.5060.8791.0016.27C
ATOM1260CG ASNA16522.324 19.7342.154 1.0016.91C
ATOM1261ODl ASNA16522.900 18.6532.3811.0020.15O
ATOM1262ND2ASNA16521.451 20.2673.0061.0016.17N
ATOM1263C ASNA16521.719 22.024-0.8871.0016.67C
ATOM1264O ASNA16522.028 21.642-2.0271.0016.92O
ATOM1265N SERA 16621.719 23.306-0.5411.0016.19N
ATOM1266CA SERA 16622.118 24.361-1.4531.0016.96C
ATOM1267CB SERA 16620.909 24.890-2.2551.0016.85C
ATOM1268OG SERA 16621.302 25.638-3.3981.0016.80O
ATOM1269C SERA 16622.779 25.489-0.6651.0017.69C
ATOM1270O SERA 16622.361 25.8160.4531.0016.27O
ATOM1271N GLNA16723.815 26.070-1.2501.0018.62N
ATOM1272CA GLN A16724.455 27.255-0.6881.0020.82C
ATOM1273CB GLNA16725.731 26.8750.0771.0020.52C
ATOM1274CG GLNA16726.788 26.159-0.7491.0021.67C
ATOM1275CD GLNA16727.973 25.7530.0831.0022.50C
ATOM1276OEl GLNA16728.563 26.5760.7761.0026.39O
ATOM1277NE2 GLNA16728.326 24.4710.0351.00 24.55N
ATOM1278C GLNA16724.738 28.248-1.8101.00 21.81C
ATOM1279O GLNA16724.673 27.888-2.9941.00 21.58O
ATOM1280N ARGA16825.034 29.494-1.4431.00 23.44N
ATOM1281CA ARGA16825.360 30.530-2.4121.0025.87C
ATOM1282CB ARGA16825.821 31.796-1.6861.0025.72C
ATOM1283CG ARGA16825.798 33.042-2.5551.0028.37C
ATOM1284CD ARGA16826.821 34.067-2.0921.00 32.14C
ATOM1285NE ARGA16826.464 34.700-0.8281.00 34.57N
ATOM1286CZ ARGA16825.763 35.827-0.7221.0035.59C
ATOM1287NHl ARGA16825.318 36.448-1.8081.00 36.78N
ATOM1288NH2ARGA16825.492 36.3220.4761.00 36.00N
ATOM1289C ARGA16826.462 30.062-3.3691.00 27.24C
ATOM1290O ARGA16827.385 29.359-2.9591.0027.83O
ATOM1291N GLUA16926.349 30.452-4.6331.00 29.12N
ATOM1292CA GLUA16927.375 30.149-5.6271.0031.26C
ATOM1293CB GLU A16926.796 30.192-7.0421.0031.49C
ATOM1294CG GLU A16926.098 28.916-7.4521.00 33.07C
ATOM1295CD GLU A16925.369 29.052-8.7741.00 34.47C
ATOM1296OEl GLU A16926.041 29.085-9.8321.00 36.26O
ATOM1297OE2 GLUA16924.121 29.115-8.7551.0031.69O
ATOM1298C GLUA16928.532 31.125-5.5011.0031.98C
[0595]ATOM1343OHOHC3910.03823.514 11.625 1.0019.35O
ATOM1344OHOHC401.58927.268 12.084 1.0025.47O
ATOM1345OHOHC4118.76425.989 10.989 1.0022.75O
ATOM1346OHOHC423.13931.954 10.647 1.0019.30O
ATOM1347OHOHC43-0.69823.830-11.690 1.0027.71O
ATOM1348OHOHC447.32434.542 -3.438 1.00 19.70O
ATOM1349OHOHC4515.39325.076-12.431 1.0018.83O
ATOM1350OHOHC46-2.95224.923 -10.653 1.0020.01O·
ATOM1351OHOHC478.52627.347-11.572 1.0014.42O
ATOM1352OHOHC4825.00329.995 1.360 1.0018.25O
ATOM1353OHOHC498.8514.740 -0.804 1.0044.60O
ATOM1354OHOHC502.15015.238 10.244 1.0023.34O
ATOM1355OHOHC5123.24831.543 -8.292 1.00 38.43O
ATOM1356OHOHC5211.92537.161 11.540 1.0021.41O
ATOM1357OHOHC537.50626.580 12.158 1.0017.84O
ATOM1358OHOHC5422.40320.582 5.479 1.00 22.66O
ATOM1359OHOHC552.9204.070 -8.880 1.00 27.70O
ATOM1360OHOHC5613.36520.446 -14.539 1.0031.29O
ATOM1361OHOHC573.2056.214 5.047 1.0028.77O
ATOM1362OHOHC5811.30634.224 14.484 1.00 29.77O
ATOM1363OHOHC5913.96810.048 1.479 1.0018.69O
ATOM1364OHOHC6025.94927.531 9.261 1.0031.24O
ATOM1365OHOHC6117.40329.407 -7.478 1.0016.15O
ATOM1366OHOHC624.9884.691 -5.306 1.00 17.42O
ATOM1367OHOHC630.88522.565 -9.915 1.00 21.01O
ATOM1368OHOHC6413.47222.874-13.065 1.00 18.40O
ATOM1369OHOHC657.72821.661 13.603 1.00 23.40O
ATOM1370OHOHC660.82617.054 11.904 1.0020.26O
ATOM1371OHOHC6722.08214.632 -14.560 1.0028.15O
ATOM1372OHOHC68-8.01111.229-10.833 1.0028.48O
ATOM1373OHOHC6919.86921.156-14.466 1.0028.81O
ATOM1374OHOHC708.50529.865 -10.308 1.0018.39O
ATOM1375OHOHC719.72224.355 -14.345 1.0022.96O
ATOM1376OHOHC72-9.3839.208 -12.697 1.00 37.48O
ATOM1377OHOHC7313.68312.690 -5.641 1.0016.03O
ATOM1378OHOHC7422.70316.963 4.759 1.00 25.06O
ATOM1379OHOHC75-4.66112.064 5.165 1.00 23.98O
ATOM1380OHOHC76-0.11611.262 4.335 1.0015.82O
ATOM1381OHOHC7710.96433.126 -7.385 1.0022.22O
ATOM1382OHOHC7812.74111.275 -3.598 1.0026.61O
ATOM1383OHOHC7917.1249.812 -1.247 1.00 24.04O
ATOM1384OHOHC8010.50729.065 14.092 1.0042.45O
ATOM1385OHOHC811.93230.283-11.189 1.0026.71O
ATOM1386OHOHC826.51532.337 -7.631 1.00 23.56O
[0597]ATOM1387OHOHC 83 5.835 14.658 10.607 1.00 26.21 OATOM1388OHOHC 8416.286 9.808 -5.465 1.00 32.46 O
ATOM1389OHOHC 8517.982 26.013 -14.610 1.0041.22 O
ATOM1390OHOHC 86 6.757 25.556-14.889 1.0032.09 O
ATOM1391OHOHC 8712.168 23.328 14.403 1.00 32.02 O
ATOM1392OHOHC 8825.612 18.037 0.846 1.00 3 7.22 O
ATOM1393OHOHC 89-11.612 11.941 -3.966 1.00 35.20O
ATOM1394OHOIIC 9016.837 22.905 14.860 1.0045.41 O
ATOM1395OHOHC 91 4.324 6.909 8.884 1.00 35.98 O
ATOM1396OHOHC 92-0.508 30.459 -7.690 1.0031.56 O
ATOM1397OHOHC 9323.798 25.345 -12.973 1.00 40.97 O
ATOM1398OHOHC 94-1.156 31.732 -3.874 1.0022.96 O
ATOM1399OHOHC 9524.773 23.540 7.683 1.0031.69 O
ATOM1400OHOHC 9613.370 28.961 14.118 1.0025.13 O
ATOM1401OHOHC 9711.176 32.694-14.976 1.0045.55 O
ATOM1402OHOHC 98 3.247 33.923 -4.564 1.0023.20 O
ATOM1403OHOHC 99 0.655 1.887 -9.968 1.00 33.74 O
ATOM1404OHOHC 100-1.605 27.211 6.238 1.0025.07O
ATOM1405OHOHC 10127.031 15.167 -5.294 1.0041.18 O
ATOM1406OHOHC 10212.701 37.927 -2.640 1.00 24.98 O
ATOM1407OHOHC 10311.242 17.624 16.856 1.0028.15 O
ATOM1408OHOHC 104-0.714 21.375 15.259 1.00 26.94 O
ATOM1409OHOHC 10511.116 20.520-15.920 1.00 32.85O
ATOM1410OHOHC 10626.599 26.380 -4.765 1.0027.41 O
ATOM1411OHOHC 107-3.531 30.025 -4.711 1.0031.33O
ATOM1412OHOHC 108-10.386 14.344 6.766 1.00 28.46O
ATOM1413OHOHC 109-0.920 7.733 -14.875 1.0034.53O
ATOM1414OHOHC 1103.075 25.899-13.882 1.0043.70O
ATOM1415OHOHC 1113.494 13.321 11.851 1.0041.80O
ATOM1416OHOHC 11225.115 15.319-15.164 1.0051.77O
ATOM1417OHOHC 113-10.814 3.486 -8.023 1.00 53.15O
ATOM1418OHOHC114-7.002 14.595 3.801 1.0022.94O
ATOM1419OHOHC11522.295 23.908 11.184 1.0037.30 O
ATOM1420OHOHC 11610.413 13.556-14.122 1.0031.05O
ATOM1421OHOHC 11718.144 8.726 1.052 1.0025.56O
ATOM1422OHOHC 1188.111 12.858 17.399 1.0026.70 O
ATOM1423OHOHC119-1.900 6.427 -5.476 1.00 37.96O
ATOM1424OHOHC 12026.236 17.529 -6.312 1.0042.03 O
ATOM1425OHOHC 12114.867 33.188-10.053 1.0029.76O
ATOM1426OHOHC 12218.107 30.034-14.340 1.0029.39O
ATOM1427OHOHC 12326.086 20.699 0.543 1.00 39.98 O
ATOM1428OHOH C12421.347 13.146 4.294 1.00 42.70 O
ATOM1429OHOH C125-5.395 27.500 -5.225 1.00 32.34O
ATOM1430OHOH C12619.591 11.720-11.515 1.0026.26O
[0598]ATOM1431OHOH C 127-6.1328.228 1.3601.00 31.16OATOM 1432OHOH C1285.35923.142-15.1181.0029.53O
ATOM 1433OHOH C 12928.70829.233 -0.6961.00 46.73O
ATOM1434OHOHC 13010.6135.449 6.2511.0028.10O
ATOM1435OHOHC 131-0.0076.005 -1.2971.0032.11O
ATOM1436OHOH C 13223.36815.050 11.6731.00 37.46O
ATOM1437OHOH C 13325.04619.722 -8.1201.00 33.05O
ATOM1438OHOHC 1349.42425.141 13.5651.00 33.26O ATOM1439OHOH C 13525.84714.252 11.2881.00 34.74O
ATOM1440OHOH C 13624.81729.704 8.8991.00 32.97O
ATOM1441OHOHC 13724.29633.831 12.4841.00 33.85O
ATOM1442OHOHC 1388.70027.899-14.1931.0028.62O
ATOM1443OHOHC 13923.15811.855 -6.7611.0044.27O
ATOM1444OHOHC 1405.53411.801 10.8781.00 29.38O
ATOM1445OHOHC 141-5.64531.000 -3.6511.00 30.23O
ATOM1446OHOHC 14215.88418.585 15.4411.00 38.52O
ATOM1447OHOHC1431.85616.886 14.5841.0031.21O
ATOM1448OHOHC14429.24525.474 -4.6941.0042.40O
ATOM1449OHOHC 145-8.45820.496 -7.5551.00 33.58O
ATOM1450OHOHC 146-0.83329.488 7.4181.00 24.32O
ATOM1451OHOHC 1475.24730.037-11.1751.00 35.52O
ATOM1452OHOHC 1489.48321.937-14.1761.00 30.20O
ATOM1453OHOHC 14915.29520.153 18.0891.0048.34O
ATOM1454OHOHC1500.54230.543 10.7771.00 38.34O
ATOM1455OHOHC 1519.3872.527 3.5651.00 30.25O
ATOM1456OHOHC15218.28319.624 14.9351.0031.09O
ATOM1457OHOHC1532.23132.712 -10.4631.00 37.34O
ATOM1458OHOHC1543.49426.236 15.9761.00 35.76O
ATOM1459OHOHC1550.0000.000 -3.1400.33 36.16O
ATOM1460OHOHC15629.59926.684 4.1371.00 49.58O
ATOM1461OHOHC15720.26530.811 -13.3551.00 32.27O
ATOM1462OHOHC1584.11821.799 15.1151.0043.85O
ATOM1463OHOHC 159-1.28215.362 11.9291.00 38.31O
ATOM1464OHOH C1607.00032.634 14.7851.00 58.41O
ATOM1465OHOHC161 -11.66218.007-11.3871.00 37.98O
ATOM1466OHOHC1628.62038.125 12.7421.0041.89O
ATOM1467OHOHC1630.7556.442 8.5641.0037.57O
ATOM1468OHOHC1649.65719.932 14.0771.00 33.41O
ATOM1469OHOHC16520.64832.613 -5.6841.00 34.32O
ATOM1470OHOH C166-2.8914.747 -3.8451.0036.48O
ATOM1471OHOHC1670.5998.421 11.1451.0051.34O
ATOM1472OHOHC16824.2558.505 6.3681.00 58.21O
ATOM1473OHOHC1694.5987.586 11.5191.00 51.50O
ATOM1474OHOHC1706.27712.729-15.2601.00 36.41O
[0599]ATOM1475OHOHC 1712.24233.629 -6.9051.00 36.85OATOM1476OHOH C 172-4.82629.572 5.9291.00 25.80O
ATOM1477OHOH C 1732.21534.911 0.5351.0031.20O
ATOM1478OHOH C 17418.90631.815 -7.9661.00 26.96O
ATOM 1479OHOH C 1755.85936.246 -1.6081.0019.07O
ATOM1480OHOHC 17627.50612.770 9.1181.00 36.92O
ATOM1481OHOH C177-2.2315.718 7.8071.0031.70O
ATOM1482OHOHC 178-9.59314.887 4.3721.00 32.26O
ATOM1483OHOH C 17924.42926.258 11.6041.00 36.78O
ATOM1484OHOHC 18026.27610.158 6.9891.0040.95O
ATOM1485OHOHC 18115.65931.633-14.9271.00 33.21O
ATOM1486OHOHC 1826.4395.851 12.0561.0040.31O
ATOM1487OHOH C18323.33820.398 14.2961.0046.16 O
ATOM1488OHOHC184-7.59015.805-11.1581.00 30.12O
ATOM1489OHOHC 18525.22336.478 -5.8431.0051.46O
ATOM1490OHOHC 18614.49432.637-12.6941.00 38.92O
ATOM1491OHOHC 187-1.68832.074 11.5901.0043.26O
ATOM1492OHOHC 1889.14535.161 -11.0701.0042.52O
ATOM1493OHOHC 18925.40616.009 8.6141.00 54.32O
ATOM1494OHOHC 19023.10817.782 14.3981.00 49.04O
ATOM1495OHOHC1914.79735.701 2.1131.0013.86O
ATOM1496OHOHC 19211.3138.379 9.7321.00 14.54O
ATOM1497OHOHC 19325.138 8.254 9.5041.00 40.56O
ATOM1498OHOHC 194-5.24831.572 4.3591.0016.20O
ATOM1499OHOHC 1953.55234.777 -1.8361.0016.79O
ATOM1500OHOHC 19615.84331.625 -0.6581.0014.25O
ATOM1501OHOHC 19718.26037.087 9.6501.00 29.40O
ATOM1502OHOHC1986.01616.515 17.3661.00 32.02O
ATOM1503OHOHC 19918.17332.351 1.6621.00 16.19O
ATOM1504OHOH C 200-6.3391.106 -9.3541.00 30.70O
ATOM1505OHOH C 2019.3562.408 -1.6351.0041.48O
ATOM1506OHOH C 202-2.95729.499 -7.4721.00 39.78O
ATOM1507OHOH C 20316.71837.857 -3.8571.00 53.51O
ATOM1508OHOH C 20424.45017.663 -9.9321.0043.97O
ATOM1509OHOH C 20520.77123.401 9.0911.0021.18O
ATOM1510OHOH C 20617.99114.996 15.3341.00 34.03O
ATOM1511OHOH C 20714.78513.418 15.0351.0023.11O
ATOM1512OHOH C 20821.36410.070 0.9381.00 43.98O
ATOM1513OHOH C 20917.44632.692 15.0441.00 32.28O
ATOM1514OHOH C 210-4.097-0.566 -2.5251.00 43.94O
ATOM1515OHOH C 211-7.60116.797-13.6421.00 30.53O
ATOM1516OHOH C 212-6.40217.493 -9.4171.0032.47O
ATOM1517OHOH C 21320.47912.017 -6.3681.00 41.20O
ATOM1518OHOH C 21426.23315.387 -8.7631.00 61.51O
[0600]ATOM1519OHOH C 2158.17130.282 14.2731.0047.43 OATOM1520OHOH C 216-4.8602.481 -3.3651.00 36.97O
ATOM1521OHOH C 2177.25313.009-17.7781.00 34.50O
ATOM1522OHOH C 21831.88926.105 0.328 1.0048.69 O
ATOM1523OHOH C 21923.80131.899 -5.2891.0037.45 O
ATOM1524OHOH C 2208.04920.377 15.946 1.0046.50 O
ATOM1525OHOH C 2211.12835.425 -1.0611.00 32.18 O
ATOM1526OHOH C 2220.7363.120-12.9591.00 49.39O
ATOM1527OHOH C 2235.71434.194 -5.5981.0045.92 O
ATOM1528OHOH C 22432.46223.398 -0.6041.0052.94 O
ATOM1529OHOH C 22522.92012.668 -2.3961.0042.31 O
ATOM1530OHOH C 226-10.46820.039 -4.5051.0031.70O
ATOM1531OHOH C 227-9.57120.524 7.6911.00 33.23O
ATOM1532OHOH C 228-5.51224.361-11.4211.0041.21O
ATOM1533OHOH C 22929.13019.154 -2.1281.0044.72 O
ATOM1534OHOH C 23026.07916.595-13.1261.0040.17O
ATOM1535OHOH C 2318.24933.990 -6.3441.00 37.22O
ATOM1536OHOH C 232-6.36923.852 -2.5421.00 30.86O
ATOM1537OHOH C 23328.02513.978-14.5971.0041.20O
ATOM1538OHOH C 2344.52627.966-13.9751.00 57.38O
ATOM1539OHOH C 23519.66219.264 17.2531.0045.54 O
ATOM1540OHOH C 2366.20728.046 13.9131.0039.03 O
ATOM1541OHOH C 23721.46921.107 19.172 1.0036.45 O
ATOM1542OHOH C 23820.2413.932 14.0471.00 24.86 O
ATOM1543OHOH C 23923.00312.985 -9.5931.0041.28 O
ATOM1544OHOH C 24020.82020.952 10.196 1.0026.99 O
ATOM1545OHOH C 241 -13.04310.647 -0.9571.00 44.71O
ATOM1546OHOH C 242 -12.46323.019 9.4341.00 35.64O
ATOM1547OHOH C 24316.93713.054 16.827 1.0028.17 O
ATOM1548OHOH C 24410.81636.185 -5.8801.00 34.97 O
ATOM1549OHOH C 24529.50738.709 0.8971.00 30.98 O
ATOM1550OHOH C 246-6.98419.997 -9.4971.00 36.75O
ATOM1551OHOH C 24723.2278.607 1.9271.00 36.74 O
ATOM1552OHOH C 2487.4311.768-12.5831.00 34.07O
ATOM1553OHOH C 249-1.14535.666 -3.7301.00 32.73O
ATOM1554OHOH C 250 -10.30318.635 9.4131.0027.27O
ATOM1555OHOH C 25124.49711.680-11.7611.00 43.83O
ATOM1556OHOH C 25222.035-1.582 4.3571.0031.60O
ATOM1557OHOH C 25312.85934.955 -6.8651.0046.12 O
ATOM1558OHOH C 254-0.41519.213 17.1441.00 33.59 O
ATOM1559OHOH C 255-7.392-0.762-13.4461.0038.50O
ATOM1560OHOH C 25622.35724.323 19.9211.00 39.95 O
ATOM1561OHOH C 25725.10817.891 18.040 1.0046.55 O
ATOM1562OHOH C 258-10.54416.883 7.5341.00 42.60O
[0601]ATOM1563OHOH C 259-1.8239.27010.4401.00 42.68OATOM1564OHOH C 2600.03832.968-8.2631.00 49.96O
ATOM1565OHOH C 261-2.95737.760-3.6491.00 45.46O
ATOM1566OHOH C 26216.070 16.43019.6601.0046.71O
ATOM1567OHOH C 263-7.82921.465-12.3801.00 37.90O
ATOM1568OHOH C 264-5.38110.77510.9121.00 54.26O
ATOM1569OHOH C 26531.41119.412-9.9991.00 57.72O ATOM1570OHOH C 26617.650-0.22011.4421.00 25.86O
ATOM1571OHOH C 26722.7036.0182.2671.00 31.89O
ATOM1572OHOH C 26824.287-0.9282.4761.00 56.27O
ATOM1573OHOH C 2690.0000.0005.9170.33 41.08O ATOM1574OHOH C 2704.3151.035-18.1331.0046.45O
ATOM1575OHOH C 27125.9628.4752.4481.0031.32O
ATOM1576OHOH C 27222.17126.49518.4471.00 33.86O
ATOM1577OHOH C 27336.94019.863-1.2221.00 38.39O
ATOM1578OHOH C 27437.58019.5291.6761.00 40.36O
ATOM1579OHOH C 275-1.79734.546-7.3511.00 42.77O
ATOM1580OHOH C 276-13.66315.4137.3931.00 33.48O
ATOM1581OHOH C 27715.69823.45020.9731.0042.32O
ATOM1582OHOH C 278-3.88533.689-6.0051.00 52.43O
ATOM1583OHOH C 27928.33740.5917.8981.00 40.16O
ATOM1584OHOH C 28033.93023.410-9.4681.0044.18O
ATOM1585OHOH C 2812.8069.01212.9591.0047.36O
ATOM1586OHOH C 28210.31539.45714.7141.0040.30O
ATOM1587OHOH C 283-0.00338.067-8.7930.33 46.57O
ATOM1588OHOH C 284-0.8279.2066.9581.00 24.57O
ATOM1589OHOH C 28510.5578.220-2.7951.00 29.67O
ATOM1590OHOH C 28610.6719.3900.7801.00 18.38O
ATOM1591OHOH C 2872.51137.0771.3031.0027.43O
ATOM1592OHOH C 28810.6715.91310.4081.0028.27O
ATOM1593OHOH C 28912.1799.861-1.4401.00 34.08O
ATOM1594OHOH C 2909.0487.318-0.2711.00 25.03O
ATOM1595OHOH C 291-0.00138.0722.4370.33 9.24O
[0602](实施例6)各种变异型蛋白质的结合能的确认
[0603]除了使用了变异型Hd3a和变异型GF14c以外，通过实施例I所记载的方法对相互作用进行了确认。变异型 Hd3a(R55A、M63A、R64A、P96L、F103A、R132A、R168A)和变异型 GF14c(F200A、I204A、E212A、Y215A、R226A)是使用 Quickchange 定点突变试剂盒(Stratagene公司）并根据试剂盒的说明书进行制备。需要说明的是，所谓的“R55A”是指在Hd3a中将第55位的精氨酸（R)取代为丙氨酸（A)后的变异型Hd3a蛋白质。
[0604]结果如图5 所示。在变异型 Hd3a 中，M63A、R64A、P96L、F103A、R132A 的与 GF14c 的结合能降低。特别是F103A的结合能显著降低（图5a)。在变异型GF14c中，F200A、I204A、E212A、Y215A的与Hd3a的结合能降低，特别是F200A、I204A的结合能显著降低（图5b)。
[0605](实施例7)成花素激活复合物与C-boxDNA的凝胶迁移实验[0606]C-boxDNA使用了源自鼠耳芥API启动子的序列（22碱基对：5' -CTTCACGAGACGTCGATAATCA-3'(序列编号5))。实验中所使用的C_box DNA通过化学合成进行制备。成花素激活复合物的调制中使用了含有O. 2mM EDTA(乙二胺四乙酸）、1.5mMMgCl2、5%甘油的IOOmM Tris-borate缓冲液。成花素激活复合物（FDl-GF14_Hd3a)(有时也称为“FAC”）与 C-box DNA 的结合体，是通过将 30pmolC-box DNA、40pmol 0sFDl、40pmolGF14c以及80pmol Hd3a混合，在4°C下培养30分钟并使其反应而生成的。对于生成的结合体，通过使用10%丙烯酰胺凝胶进行电泳并进行溴化乙锭染色而进行了检测。
[0607]结果如图6所示。可知成花素激活复合物与C-boxDNA结合且在DNA上形成了稳定的复合物（泳道4)。可以认为Hd3a是在启动子上形成成花素激活复合物，并进行成花所需的基因的转录激活的物质。
[0608](实施例8)成花素与14-3-3蛋白同种型的相互作用的确认
[0609]使用酵母双杂交实验对各蛋白质的相互作用进行了确认。
[0610]首先，如下那样进行了质粒的构建。对于0sGF14a(0s08g0480800)、0sGF14b(0s04g0462500)、0sGF14c(0s08g0430500)、0sGF14d(Osllg0546900)、0sGF14e(0s02g0580300)、0sGF14f(0s03g0710800)、0sGF14g(0s01g0209200)、OsGF14h (0sllg0609600)、OsFDl (0s09g0540800)，通过 RT-PCR 对全长的 cDNA 进行了克隆。根据水稻DNA数据库中的基因信息设计了正向引物和反向引物。将编码区域全长进行PCR扩增，并导入到pENTR/D-TOPO克隆载体（Invitrogen)中，由此得到了入门克隆。
[0611]利用非专利文献2中记载的方法进行了 Hd3a的相互作用因子的筛选。通过使用从野生型的叶片中提取的总RNA制备了酵母双杂交文库。在利用cDNA合成试剂盒(Stratagene)合成了 cDNA 之后，将 cDNA 插入到 pVP16 载体（Hollenberg et al. , 1995)中，并导入到酵母L40株中。作为诱饵（bait)，将Hd3a ORF的全长克隆至pBTM116载体(Bartel et al.，1993)中。利用不含组氨酸而含有2. 5mM 3-氨基三唑(3-AT)的SC培养基进行了筛选。
[0612]为了相互作用实验，使用Gateway载体转化系统（Gateway vector conversionsystem) (Invitrogen)并按照制造商的操作指南而将pBTM116和pVP16转换成pBTM116_GW和PVP16-GW。使用在SC培养基（不含尿嘧啶、色氨酸、亮氨酸、组氨酸）中添加了组氨酸或ImM〜IOmM 3-氨基三唑的培养基（+His或+3-AT)使酵母在30°C下生长了 5天。3-AT的浓度根据诱饵与猎物（bait-prey)的组合而决定。
[0613]结果如图7所示。可知显示GF14b、C、e、f (0sGF14b、C、e、f)与Hd3a相互作用。以下的实施例中使用了 GF14b。
[0614](实施例9)有助于三种蛋白质的相互作用的部位的确认
[0615]通过如下那样构建质粒而制备了各种变异型蛋白质。向0sGF14、0sFDl、Hd3a的氨基酸的取代或缺失的导入通过PCR并利用KOD FX DNA聚合酶（Τ0Υ0Β0)来进行。将PCR扩增片段克隆到PENTR/D-T0P0克隆载体（Invitrogen)中，由此得到了入门克隆。在得到的入门克隆中表达的变异型蛋白质，对于OsFDl而言为S192A、S192E，对于OsGFHb而言为R64A/R68A、I277A/L230A、F206A、I210A、E212A、E218A、Y221A、R232A、D233A,对于 Hd3a 而言为 R64G、R64A、R64K、T68I、P96L、F103A、R132A、R132K、R64G/R132A、R64K/R132K。与实施例8同样，使用这些入门克隆对相互作用进行了确认。[0616]需要说明的是，变异型蛋白质中使用“/”表示的变异型蛋白质为多重变异型，例如，Hd3a的“R64G/R132A”是指第64位的精氨酸（R)向甘氨酸（G)的取代和第132位的精氨酸（R)向丙氨酸（A)的取代的双重变异型Hd3a蛋白质。[ 0617]结果如图8a〜d所示。
[0618]可知在OsFDl与0sGF14b的相互作用中，OsFDl的第192位的丝氨酸的磷酸化很重要（图8a)。
[0619]OsGF14b 的变异型蛋白质中的将 F206、I210、E212、E218、Y221、R232、D233 取代后的变异型蛋白质与Hd3a的结合能降低，但是，其与OsFDl的结合能未受影响（图Sc)。
[0620]財3&的变异型蛋白质中的将1?64、了68、？96、？103、1?132取代后的变异型蛋白质与OsGF14b的结合能显著降低（图8d)。在Hd3a的变异型蛋白质中的P77L、R121H的情况下，其与OsGFHb的结合能未受影响，因此，这暗示这些部位对于与14-3-3蛋白的结合而言不重要。
[0621](实施例10)水稻茎顶端的相互作用的确认
[0622]使用体内pull-down实验对水稻植物的莖顶端的相互作用进行了确认。
[0623](I)所使用的植物材料
[0624]将水稻（Oryzasativa L. subsp. Japonica) variety Norin 8 作为野生型进行使用。按照 Tamaki et al. , Science316,1033 (2007), Okano et al. , Plant J. 53,65 (2008)的记载而制备了转化水稻(pHd3a: :Hd3a: :GFP、p35S: :GFP、prolC: :Hd3a: :GFP)。转化水稻是按照Hiei et al. Plant J. 6，271 (1994).的记载且通过使用土壤杆菌转导至水稻愈伤组织来进行制备，由此从被转化转导的愈伤组织制备了潮霉素抗性植物。从制备的植物中提取基因组DNA，并对潮霉素磷酸转移酶（HPT)基因进行PCR扩增，由此对转基因的整合进行了确认。
[0625]需要说明的是，所谓的“pHd3a: :Hd3a: :GFP”是指导入了使Hd3a的启动子区、Hd3a的编码区全长以及GFP的编码区连结后的基因的转化水稻，以下有时也简称为“HHG”。所谓的“p35S: :GFP”是指导入了使CaMV 35S启动子与GFP的编码区连结后的基因的转化水稻，以下有时也简称为“35S GFP”。所谓的“prolC: :Hd3a: :GFP”是指导入了使rolC的启动子区、Hd3a的编码区全长以及GFP的编码区连结后的基因的转化水稻。
[0626](3)体内 pull-down 实验
[0627]在显微镜下从HHG转化水稻和35S GFP转化水稻将茎顶端部位的试样切除并回收。在将上述试样磨碎后，将各试样的粉末分别溶解于100 μ I提取缓冲液（150mM NaCl,50mM Tris、0. 1% 吐温 _20、10% 甘油、ImM DTTUmM Pefabloc SC [Roche]、Ix 的 Complete 蛋白酶抑制剂混合物[Roche]、Ix的Halt磷酸酶抑制剂混合物[Pierce])中并加以混合。在离心分离后（15min、4°C、15000rcf)，将上清液转移至试管中，并通过考马斯亮蓝染色实验对蛋白质量进行了测量。对于与从HHG转化水稻和35SGFP转化水稻提取的全蛋白质量等量的物质，利用50μ1 anti-GFP MicroBeads (Mi ltenyi Biotec),除追加以下的变更以外,按照制造商的操作指南进行了培养：回收流通（flow-through)并用于进一步的分析中。
[0628]利用200 μ I 提取缓冲液（150mM NaCl、50mM Tris、0. I % 吐温-20、10 %甘油、ImMDTT>ImM PefablocSC[Roche]、Ix 的 Complete 蛋白酶抑制剂混合物[Roche] >Ix 的 Halt磷酸酶抑制剂混合物[Pierce])将层析柱刷洗了 4次。之后，利用100 μ I的低离子缓冲液（20mM TrisHCl、pH为7· 5)清洗了 I次。之后，将层析柱从磁場（magnetic field)中除去，并利用50 μ I的裂解缓冲液对剩余的蛋白质进行了提取。利用12. 5%的SDS-PAGE对洗脱液进行了分离，并使用一级抗体（多克隆兔抗GFP抗体（Abcam))和抗14_3_3抗体(从Dr. Yohsuke Takahashi (广岛大学，日本）获赠）进行了免疫印迹。在利用TBST清洗之后，利用辣根过氧化物酶结合抗兔IgG(GE Healthcare)将膜培养了 I小时。使用增强化学发光法(ECL)蛋白凝胶印迹检测试剂(protein gel blot detection reagents) (GEHealthcare)进行了检测，并使用 LAS-4000 mini Imager (Fujifilm)进行了可视化。
[0629]结果如图9所示。图9的左侧（上样）表示：从使GFP或者Hd3a_GFP融合蛋白质表达了的转化水稻（35S GFP转化水稻或HHG转化水稻）的茎顶端的细胞中提取蛋白质，并使用抗GFP抗体（α-GFP)和抗14_3_3抗体（a-14-3-3)进行了免疫印迹的结果。图9的右侧（IP-GFP)表示：对于从茎顶端的细胞提取了蛋白质的提取液，在利用抗GFP抗体(a-GFP)进行了免疫沉淀（IP)后，同样地进行了免疫印迹的结果。在使Hd3a_GFP融合蛋白质表达了的情况下（HHG的提取液），在利用抗GFP抗体进行的共沈淀中观察到了 14-3-3蛋白，但是，在仅使GFP表达了的情况下（35S GFP的提取液），在共沈淀中未观察到14_3_3蛋白。由此可知，Hd3a与14-3-3蛋白在水稻的茎顶端相互作用。·
[0630](实施例11)三种蛋白质及它们的复合物的细胞内定位
[0631]细胞内定位和双分子突光互补法（Bimolecular FluorescenceComplementation :BiFC 法）如下那样进行。
[0632]首先，将Hd3a、GF14b、OsFDl以及β _葡萄糖醛酸酶（GUS)的编码区克隆至荧光蛋白表达载体或BiFC载体上,并使用Purelink质粒中量提取试剂盒（Invitrogen)进行了提纯。对Hd3a、GF14b、OsFDl以及它们的变异型蛋白质，使用了编码区全长。作为荧光蛋白表达载体而使用了表达GFP、CFP或者mCherry的载体。作为BiFC载体而使用了表达Vn或Vc标记的载体。Vn或Vc在靠近存在时会发出作为Venus (mVenus)的荧光。
[0633](I)利用 Kyozuka and Shimamoto 1991, Plant J. 6, 271 (1994)、非专利文献 I 等中记载的方法进行了水稻Oc原生质体的转化。利用PEG法（PEG-mediated method)将导入了各种蛋白质后的突光蛋白表达载体导入到原生质体悬浮液（2X 107protoplasts/ml)。在30°C下培养了 24小时后，得到转化后的原生质体，并用于显微镜下的观察。
[0634]在同时表达2种蛋白质的系统中，将Iyg的GFP-GF 14b表达质粒或Hd3a-mCherry 表达质粒、和 10 μ g 的 NLS-CFP、CFP-OsFDI 或 CFP-OsFDl S192A 表达质粒同时转化成原生质体。所谓的“NLS”是指核定位信号肽。
[0635]结果如图10所示。Hd3a_mCherry的荧光在细胞质和细胞核的两者中被检测到，GFP-GFHb在细胞质中被检测到，CFP-OsFDI在细胞核内被检测到。
[0636](2)与（I)的方法同样地，在BiFC法中，对5μ g的Vn融合蛋白表达载体和Vc融合蛋白表达载体同时进行了转化。
[0637]将mCherry表达质粒作为转化効率的标记而同时导入。
[0638]为了将蛋白质-蛋白质相互作用定量化，对于导入了 BiFC分析用表达质粒（Vn融合蛋白表达载体、Vc融合蛋白表达载体、mCherry表达质粒）的各种原生质体约20个细胞，在同样的显微镜条件下测量了 mCherry和Venus的突光强度,并算出了 Venus/mCherry值。将下述细胞作为BiFC信号可信赖的细胞，即，在本实验条件下，对于Hd3a与GF14b的相互作用而言Venus/mCherry > O. 33，并且对于GF14b与OsFDl的相互作用和Hd3a与OsFDl的相互作用而言Venus/mCherry > O. 4的细胞。因此,在显示比上述值更高的值时对细胞的数量进行了计数。
[0639]结果如图11所示。
[0640]使Vn或Vc与Hd3a和GF14b的N末端和C末端结合，并在水稻原生质体中进行了表达，结果是BiFC信号在细胞质内发现了 Hd3a与GF14b的相互作用，这取决于Hd3a的R64和R132的变异（图Ila)。在BiFC法中，GF14b的R58和R62的变异未对Hd3a与GF14b的相互作用产生影响。
[0641]接着，对GF14b与OsFDl的相互作用进行了确认，结果未在细胞质内观察到两者的相互作用。GF14b与OsFDl的相互作用主要在细胞核内被检测到，而在细胞质中仅确认到GF14b的定位（图Ilb)。可知OsFDl的S192的变异阻碍OsFDl与GF14b的相互作用。另夕卜，在BiFC法中，GF14b的R58和R132的变异未对GF14b与OsFDl的相互作用产生影响。
[0642]对Hd3a与OsFDl的相互作用进行了确认后得知，Hd3a与OsFDl的复合物存在于细胞核内（图lie)。Hd3a与OsFDl的相互作用被Hd3a的R64和R132的变异或者OsFDl的S192的变异阻碍。
[0643](3)与（I)的方法同样地，在确认Hd3a与GF14b的相互作用的BiFC系统中，制备了同时表达OsFDl的细胞，并对BiFC信号在细胞核内的累积量进行了研究。为了在BiFC法中同时表达NLS-CFP和CFP-OsFDI，使用了 10 μ g的NLS-CFP表达质粒和CFP-OsFDI表达质粒。
[0644]对细胞核内的累积量的计算方法进行了确定。首先，对转化细胞的细胞核内的Venus和mCherry的荧光强度进行了测量。之后，算出了（细胞核内Veuns/细胞核内mCherry) / (细胞整体的Venus/细胞整体的mCherry)的值。这表示Venus和mCherry在细胞核内的累积量的比率。对上述值与从各细胞得到的对应的共聚焦图像进行比较，并且与mCherry的分布进行比较，当为大于I. 2的值时定位于细胞核内，当为O. 8〜I. 2的值时定位于细胞核和细胞质的两者中，当小于O. 8时定位于细胞质内。 [0645]结果如图12所示。
[0646]在同时表达了 GFP-GFHb和NLS-CFP时，在细胞质内发现了 GFP的荧光。在瞬时同时表达GFP-GFHb和CFP-OsFDI时，在细胞核内发现了 CFP的荧光，并且在细胞核内也观察到GFP的荧光，这与同时表达了 NLS-CFP时显著不同。另一方面，在同时表达了 OsFDl的变异型蛋白质S192A与GFP-GFHb时，未观察到GFP的荧光向细胞核内的移动（图12a)。这暗示GF14b的定位由于OsFDl的存在而从细胞核内转移至细胞质内。
[0647]在同时表达了 Hd3a_mCherry和CFP-OsFD I时，与仅与CFP同时表达时相比较，mCherry在细胞核内的累积量增大。在同时表达了 OsFDl的变异型蛋白质S192A和Hd3a-mCherry时，未发现细胞核内的累积量的增大（图12b)。这些结果暗示Hd3a和GF14b从细胞质移动至细胞核中并与OsFDl形成复合物。
[0648]为了确认OsFDl对Hd3a与GF14b的复合物的定位的影响而同时表达了 BiFC法和CFP-OsFDI。在未表达OsFDl的情况下，得知Hd3a与GF14b的复合物（BiFC信号)存在于细胞质内。进而，当将CFP-OsFDl同时表达时，观察到Hd3a与GF14b的复合物明显集中在细胞核内（图12c)。因为OsFDl同时表达而引起的Hd3a与GF14b的复合物的移动通过向GF14b中导入R58A/R62A的变异而减少。这暗示水稻细胞内的各蛋白质的定位情况如下，即，首先在细胞质内形成Hd3a与GF14b的复合物，通过GF14b与OsFDl的相互作用，而使该Hd3a和GF14b的复合物与OsFDl在细胞核内相互作用。
[0649](实施例12)OsFDl、GF14b以及Hd3a的相互作用对0sMADS15转录控制的影响
[0650]使用利用了原生质体的瞬时表达实验，对OsFDl、GF14b以及Hd3a的相互作用对OsMADS15转录控制的影响进行了确认。
[0651]通过Kyozuka and Shimamoto 1991, Plant J. 6, 271 (1994)、非专利文献 I 等中记载的方法进行了水稻Oc原生质体的转化。利用PEG法（PEG-mediated method)将8 μ gHd3a表达载体和16 μ g OsFDl表达载体导入到500 μ I的原生质体悬浮液（2 X 107protoplasts/ ml)中。在30°C下培养了 24小时后，对原生质体悬浮液进行离心，并在-80°C下使细胞颗粒冻结以便进行RNA提取。
[0652]与源自玉米的泛素启动子、NOS终止区（Miki and Shimamoto, Plant CellPhysiol. 45，490 (2004))、以及T7标签区或HA标签区一起将attR重组区（Nakagawa etal. ,2007)插入到 pGreen II 载体(Hellens et al. ,Plant Mol. Biol. 42，819 (2000))中，由此制备了 pGII pUbq GW-T7 和 pGII pUbq HA-Gff0
[0653]利用基于Gateway BP clonase II (Invitrogen)的 Gateway 重组法，将插入到pENTRD-TOPO载体中的Hd3a基因、OsFDl基因或者它们的变异型基因转化成pGII pUbqGW-T7 和 pGII pUbq HA-Gff (pGIIpUbqHd3a-T7, pGIIpUbqHA-OsFDU pGIIpUbqHA-OsFDUpGIIpUbqHd3a-T7)。将各种Hd3a表达载体、OsFDl表达载体导入到原生质体中而将各种蛋白质加以表达，从而对OsMADS 15的RNA表达量进行了确认。需要说明的是，由于0sGF14通常在所有细胞中均恒定表达，因此，认为即使导入了 0sGF14也不能发现効果。
[0654](2)如下那样进行了 RNA提取和实时PCR分析。
[0655]回收了野生型和转基因植物的叶片。使用TRizol试剂（Invitrogen)并按照制造商的说明提取了总RNA。使用寡聚dT引物（21-mer)由I μ g的RNA或2 μ g的RNA合成了cDNA,并利用Superscript II逆转录酶(Invitrogen)进行了逆转录。对于I μ I的cDNA,使用基因特异性引物并利用SYBR Green PCR master mix (Applied Biosystems)进行了定量基因表达分析。使用ABI PRISM 7000序列检测系统并按照其指南手册得到了数据。泛素(Ubquitin)和 OsMADS 15 用的引物依照于Komiya et al. ,Development 135,767(2008)·。GF14b和GF14e用的引物如下。
[0656]GF14b-realF GCGGAAGAGATCAGGGAAG (序列编号 4)
[0657]GF14brealR CGACAACAATCACAGCCACA (序列编号 5)
[0658]GF14erealF CAAGGGCGAATCAGGAGA (序列编号 6)
[0659]GF14e realR TGAAACGATAACCCACAGCA (序列编号 7)
[0660]结果如图13所示。
[0661]通过将Hd3a和OsFDl同时转导，0sMADS15的RNA量经时性地增加。在仅转导Hd3a或OsFDl时，OsMADS15的RNA表达量没有增大。在转化4小时后发现0sMADS15激活开始进行，这暗示出Hd3a和OsFDl的快速响应性(图13a)。
[0662]将各种变异型Hd3a与OsFD I同时表达的结果如图13b所示。变异型Hd3a Y87H并未促进0sMADS15转录。变异型Hd3a R64G、R132A稍微减少了 0sMADS15的表达。变异型Hd3a R64K、R64K/R132K显著减少了 OsMADS15的表达。这些结果暗示出，Hd3a与0sGF14的相互作用是OsMADS15的表达所必需的，并且，疏水性而并非精氨酸的正电荷对Hd3a与0sGF14的相互作用很重要。
[0663]将各种变异型OsFDl与Hd3a同时表达的结果如图13c所示。可知当OsFDl中缺失了 SAP基序时（图13c的“1-191”是由1-191残基构成的片段，其后的氨基酸缺失）或者SAP基序中的丝氨酸取代为丙氨酸时（S192A)，0sMADS15的RNA累积量显著降低。在SAP基序中的丝氨酸被取代为作为模拟磷酸化突变的谷氨酸时（S192E)，未发现0sMADS15的RNA累积量降低。上述情况暗示由14-3-3蛋白来识别OsFDl的SAP基序的磷酸化丝氨酸对于成花素激活复合物的形成很重要。
[0664](实施例13-1)转化水稻中的成花时期的确认
[0665]与实施例10同样地制备了表3中记载的转化水稻，并对成花时期进行了确认。 [0666]使植物在湿度70 %下在短日照（SD)条件（30°C、10小时的光照期和25 V、14小时的黑暗期的周期）的室内、或者长日照（LD)条件（14小时的光照期和10小时的黑暗期的周期）的室内生长。在光照期中，使用白色荧光管（400nm〜700ηπι、100μπιΟ1 .HT2^s-1)进行了光照射。按照Kyozuka and Shimamoto, 1991的记载对水稻悬浮培养细胞进行了维持。使植物在湿度80%下在短日照（SD)条件的室内生长。将直至开花为止的时间作为将Ttl转基因植物转移到SD条件后至抽穗（heading stage)为止的天数而进行了测定。
[0667]结果如图14和表3所示。源自导入了 prolC: :Hd3a: :GFP的转化水稻的Hd3a-GFP蛋白质从茎顶端移动，从而在转化水稻中有力地促进了成花。将prolC: :Hd3a(R64G) : :GFP(rolC的启动子区、R64G变异型Hd3a的编码区以及GFP的编码区连结后的基因)、和 prolC: :Hd3a(R64G/R132A) : :GFP(rolC 的启动子区、R64G/R132A 双重变异型Hd3a的编码区以及GFP的编码区连结后的基因）导入到水稻中，并对成花时期进行了确认。与导入了 prolC: :Hd3a: :GFP的转化水稻（19. 6± 12. 3days)相比较，导入7 prolC: :Hd3a(R64G) : :GFP 的转化水稻(44. 2±7· 8days)和导入了 prolC: :Hd3a(R64G/R132A) : :GFP的转化水稻（58. 8 ±9. 3days)的成花促进显著减少，后者几乎与野生型植物没有区别。上述情况暗示出由于Hd3a和14-3-3的亲和力降低而使成花促进能力丧失。
[0668]接着，对导入了 OsFDl RNAi的水稻与OsFDl表达转化水稻、导入了变异型OsFDl的转化水稻进行了分析。导入了 OsFDl RNAi的水稻与野生型相比成花延迟。OsFDl表达转化水稻(pUbq: :OsFDl)和导入了变异型 OsFDl S192A 的转化水稻(pUbq: :OsFDl (S192A))的成花未受影响，导入了变异型OsFDl S192E的转化水稻（pUbq: : OsFDl (S192E) (S192模拟磷酸化））与野生型相比促进了成花。
[0669][表3]
[0670]_基因型直至开花为止的时间（天） η
野生型__54. 9±9. 7__8
prolC: :Hd3a: :GFP~Ϊ9·6±12·313 '
prolC: : Hd3a (R64G) : : GFP~4. 2 + 7.86 '
prolC: :Hd3a(R64G/R132A) : :GFP58.8 + 9.321~
野生型 *— 69·5±6·(Τ4* "
OsFDlRNAi*~?4.6±4.8*7* '
pUbq: :OsFDl58.0±6. I3
[0671](实施例13-2)转化水稻的成花时期的确认
[0672]与实施例13-1同样地制备了转化水稻，并对成花时期进行了确认。
[0673]利用与实施例13-1同样的方法使植物（转化水稻）生长，并将直至开花为止的时间作为将Ttl转基因植物转移到SD条件后至抽穗（heading stage)为止的天数而进行了测定。
[0674]结果如图16和表4所示。与实施例13-1同样，在prolC::Hd3a::GFP转化水稻中，Hd3a-GFP蛋白质从茎顶端移动，从而在转化水稻中有力地促进了成花。与导入了prolC: :Hd3a: :GFP 的转化水稻相比较，导入了 prolC: :Hd3a(R64G/R132K) : :GFP 的转化水稻和导入了 prolC:Hd3a(F103A) : :GFP (rolC的启动子区、F103A变异型Hd3a的编码区以及GFP的编码区连结后的基因)的转化水稻的成花未被促进。
[0675][表 4]
[0676]
[0677]产业上的利用可能性
[0678]本发明的晶体能够带来对于植物的成花控制机制的阐明重要的成花素激活复合物的立体结构信息，并且，能够作为用于进一步研究成花调节机制的材料而使用。另外，根据得到的立体结构信息、特别是成花素激活复合物中的结合部位的信息，能够人为地且有效地调节植物的成花。根据通过本发明得到的立体结构信息，能够得到在农业生产物的收量增加或育种的効率化等中能够广泛利用的转基因植物。另外，利用本发明的立体结构信息能够对调节植物的成花的物质进行筛选，该物质能够在各种环境下调节植物的生长，从而认为在农业上是有益的。
